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Tobacco Products Liability Project

Outline of Deposition of Clarence Cook Little Taken on Behalf of Plaintiffs on November 3, 1959

Date: 03 Nov 1959
Length: 4 pages
ATMXPRIV00013038-ATMXPRIV00013041
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Abstract

Outlines direct examination, cross-examination, and redirect examination of Clarence Cook Litte, taken on behalf of plaintiffs, and includes the page numbers where complete responses can be found in the deposition transcript. Includes brief summaries of Little's responses to questions regarding his role on the Scientific Advisory Board (SAB) of the Tobacco Industry Research Committee (TIRC). Includes summary responses to questions regarding Little's awareness of the existence of various animal and human studies which have linked smoking and cancer and his assessment of the conclusions to which these studies arrived. Notes Little's statement that none of the statistical studies done have demonstrated a causational relationship between smoking and cancer. Mentions Hill & Knowlton's relationship to TIRC.

Fields

Named Organization
American Cancer Society
American Tobacco Company
Hill & Knowlton Inc. (Tobacco industry PR firm, 1953-68)
Public relations firm for the tobacco industry from 1953 through 1968.
Liggett & Myers Inc. (Pioneer in the generic cigarette business)
Cigarette manufacturer; Pioneer in the generic cigarette business; L&M is the manufacturer of Chesterfield, Decade, Dorado, Duke of Durham in 1958, Eagle, Eve, L&M, Lark, Pyramid and Stride cigarettes
*Scientific Advisory Board (SAB) (Only use SAB with name of specific org.)
Tobacco Industry Research Committee (TIRC) (Renamed Council for Tobacco Research-USA (CTR))
Organized in 1954 as the Tobacco Industry Research Committee (TIRC), and renamed the Council for Tobacco Research-USA (CTR) in 1964.
Named Person
Blatnik, John A. (Representative (D - Minnesota), subcommittee chairman)
Hammond, Edward Cuyler, Sc.D. (Epidemiologist, ACS (1950s), Plaintiff's Expert)
PMI
Hanmer, Hiram R., Ph.D. (ATC director (1896-1976))
Developed standards of measuring cigarette smoke in machines
Horn, Daniel, Ph.D. (Dir., U.S. Nat'l Clearinghouse for Smoking & Health, c. 1968)
Born: 28 May 1916, d. October 7, 1992 Frenchtown, NJ
Little, Clarence Cook, Sc.D. (CTR Scientific Director, 1954-1971)
Lumbard, Dr.
Snegireff, Dr.
Type
legal - deposition outline
Date Loaded
08 Jan 2003

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Page 1: ATMXPRIV00013038
pp, 189 192 192 Outline of Deposition of oaken on behalf of pleintiffe on ~ovenber $, 1959 not a medical doctor Scientific Director of Scientific ~ob formerly Cha/n~an of Scientific Advieory Board purpose of TZ~C to advise tobacco industry on vorthy research pro~ects, to try to fled out more about causcs of lung cancer, heart disease and other ailments supposedly related to use tobacco ?;RC includes ell tobacco co~penAes except Liggett s ~yers has vcrked on cancer in mice for $2 years but has not published original research some people cle£= • stettst~cal lationsh/p be~een smoking and l~ng cancer facte s~ov that in ~ out ~f ~0 people a~ age ~0 and i~ out of 50 the:e As no rela~ionship because they don~t have cancer when they smoke none of etatist~cal s~udtes shov causation "every stetisticel paper sho~ed ebsonce of relationsh~p in ~he r~a~orlty o~ people included An the study" Some people claim an increase An lung cancer among s:okera but no one knove boy .uch As real. Het~o~ o~ greatly improved Not true that percentage of people getting cancer la higher among emokers ~han non- s~okere according ~o preaent ATIklXPRIVO01303g Subject to Claims of Privilege and Confidentiality: Produced Pursuant to Court Orders in State oflViinnesota, et al. v. Philip Morris, et al.
Page 2: ATMXPRIV00013038
200-201 201 2O2 203 204 207 hSgher percentage o! e~okers getting cancer in so~e age groups - qualifies his answer in Ble~nik hearings ~lliSr w~Ch studies Of Ha~ond end born; he has no training in statistics He~'~ond end florn ltltiltiCl purport to higher risk he h~s of ~eveloplng lun~ cancer but H~r~nd and Horn have never p~lished thelr prt~ data Drs. Lu~ard and Sneglref~ in Boston do no~ believe ~ere £s s steady p~- g~ess ~n E~sk -- ~n can smoke affec~ing statistics at all up to certain ~int and then something hap- pens Lu~ard's original study Ilyl age of greates~ ~nc~dence of lung cancer fr~ 40 or S0 to ~5 Does no~ recall ~he~her L~ard higher incidcnce of lung cancer L~a=d d~d so ~nd ~or middle age group Dorn's s~dy shows higher incidence ~o~ "lung cance~ a~e" group a~ng smokers association between smoking a~d cancer in people in the lung cancer age thinks constitutional predisposition the ~portant factor ~n dcte~ining whet~er a shaker vii1 get lung cancer in early stages o~ X-ray, skin cancer ~n doctors who used It without the~clves e~ect between short w~ve an~ m~ny people have been s~Jecte~ to X-rays X-raM lpeciaZist has higher chance Of deveZop~ng Zeuke~la than person ~ho no~ In X-ray ~ork kn~s of no greater Incidence o~ leukemia ~ng radiologists th~n a~ng g~ne:al p~l£c -2- ATMXPRI\'O013039 Subject to Claims of Privilege and Confidentiality: Produced Pursuant to Court Orders in State of Minnesota, et al. v. Philip Morris, et al.
Page 3: ATMXPRIV00013038
Direc._____t 207°20| 208-209 210-212 212-213 225-226 216 228-229 219-220 220 222 222 was • study ehowAn9 higher incidence of cancer of scrotum among £nglish chimney sweeps than a~ong general lower incidence of cancer of the penie a~ong ~evs than among Gentiles: car- cumcision ~a¥ be a ~ewish yemen have Zess cancer of the uterus than noa-~evAsh wo~en Does not know whether those with 9renter contact vAth tuberculosis have higher incidence of At than those not connected with At exposure to tuberculosis or influenza does not create the susceptibility to the disease. Whether person who is exo posed to At gets the disease depends on his own su~ceptlble ~eople ~aM pack up a disease earlier.than they o~herwise would have by intense exposure to it can't get tuberculosis without being exposed to At but everybody who ls ex- posed to i~ does not get It~ At depends on whether the person As susceptible An ~944 as managin9 ~irector of AC$ he advised people not to inhale naterAaZ which was irrltatAng to their lungs, cludin9 s~oke, exhaust, cold air his IS44 statement was not ln~ended to show any cause and effect relatlonshAp of any de£inable nature 1~44 statement said At would be to fill lungs with fine particles in tobacco smoke 1944 statement was wrong because experi- ments of cause and effect relationship don't believe the smoke partlcles to which he referred have anything to do ~Ath cancer he has defAnltely stated that he does not thank smoking is the cause of lung cancer. Xf lc contributes anything, At As a manor factor fact that 9 out o~ 10 smokers don't get At shows that smoking As not the cause -3- ATMXPRIVO013040 Subject to Claims of Privilege and Confidentialit),: Produced Pursuant to Court Orders in State of I~4innesota, et al. v. Philip I~4orris, et al.
Page 4: ATMXPRIV00013038
Direct 223-224 224-225 226 226-227 229 23O 231 233 23,5 Dr. Hsm~ond's' opinion dlf[ers from his ~a~ond first implicated smoking and lung cancer end later £mpl~cetes smoking with a general debility because he found h~ believed to be • valid statistical cancer, cancer of prostate, cancer stomach, duodenal ulcers and cirrhosis of liver wan~s lung cancer study to continue has not made suggestions to A~o reducing ~,ounts of tar and nicotine or abou~ usln9 filters has not told Henmer eb~ut research oh relationship of smok£nq tO cancer and heart d~sease or tried to influence any of the tobacco ¢~mpsnlos' research benzpyrene Is carcinc~enic to animals but has never been found In • cancer in scientists on one of TZ~C qrsnts claimed n~co~ne affected cardiovascular system o! rabbits animal tests Indicate a line of work to be ~olloved with humans b~t results are not alveys transferable doesn't recall any york on lowering temperature of co:~ust£on in cigarettes ~or TI~C TIRC has been absolutely free from in- dustry opinion and prsssura Little's previous training and experience included 50 years of research on cause and nature of cancer in animals in his work he examined tissues but also had a ~ull-time trained pathologist tO do it -4- ATMXPRIV0013041 Subject to Claims of Privilege and Confidentiality: Produced Pursuant to Court Orders in State of Minnesota, et al. v. Philip Morris, et al.

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