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Tobacco Products Liability Project

Topic: Causation Issue

Date: 14 Mar 1985
Length: 147 pages
282005050-282005196
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Abstract

Compiles an outline of excerpts from annual reports, depositions (from Green, 1959 and from Zagurski, 1967), congressional hearings, press releases, and statements regarding the relationship between cigarettes and lung cancer. Focuses on defending the idea that there is no scientific evidence to prove that smoking causes lung cancer. Points out problems with research that claims to prove a correlation and details research that finds contradictions. Contends that the health concerns regarding smoking are greatly exaggerated.

Fields

Indexer Comment
Attachments mentioned in this document are not included.
Named Organization
AT
United States Public Health Service
U.S. Surgeon General
American Cancer Society
American Heart Association
National Cancer Institute
Sloan-Kettering Institute for Cancer Research
New York World-Telegram and Sun
Washington Evening Star
Medical Research Council
Tobacco Industry Research Committee (TIRC)
Central Council for Health Education of the Tavistock House
The American Tobacco Company
Institute of Statistics, University of North Carolina
Nature
University of Texas
Industrial Medicine and Surgery
New York University
American Medical Association (AMA)
AMA Education and Research Foundation
Medical College of Virginia
Royal College of Surgeons
Johns Hopkins University
National Institutes of Health
The Lancet
Southern Medical Association
U.S. Department of Health, Education and Welfare
University of North Carolina
Nebraska State Medical Journal
Fortune Magazine
Life Magazine
Mayo Clinic
British Empire Cancer Campaign
Yale University School of Medicine
New Zealand National Health Institute
Environmental Cancer Section, National Cancer Institute
Cambridge University
British Medical Journal
Journal of the American Medical Association
Surgeon General's Advisory Committee on Smoking and Health
The Council for Tobacco Research U.S.A. (CTR-USA)
Yale Medical School
Leeds University
Tobacco Tax Branch, Internal Revenue Service
Time
Legal Medical Institute
Mercy Hospital
National Interagency Council on Smoking and Health
New York Times
Philadelphia Inquirer
Cleveland Plain Dealer
Baltimore Sun
N.Y. Herald Tribune
Commission of Interstate & Foreign Commerce
Senate
Congress
Mosby Co.
New York State Department of Health
Newsweek
Ford Foundation
CBS
Senate Committee on Commerce
Congressional Record
H.E.W.
London Times
Medical World News
New Scientist
Journal of the Society of Occupatinal Medicine
World Health Organization
FTC
National Institute on Drug Abuse
Named Person
Heimann, Robert K.
Green
Burney, Leroy
Hammond, E. Cuyler
Wynder, Ernest
Hanmer, Hiram R.
Crowe, John Alexander
Harlow, Edward S.
Haag, Harvey B.
Horn, Daniel
Doll
Hill
Dorn, Harold F.
Hastings
Dyer
Bock
Graham
Roffo
Case, R.A.M.
Baum, William S.
Little, Clarence C.
Lumbard
Rigdon, R.H.
Cohen, Jacob
Finkner
Horvitz
Foradori
Fleischer
Monroe
Hahn, Paul M.
Walker, Robert B.
King James I
Rush, Benjamin
Tidswell, Herbert H.
Pearl, Raymond
Berkson
Hahn, Paul M.
Eastcott
Dean
Case
Cornfield
Hetsko
Magnuson
Neuberger
Haenszel
Shimkin
Levitt
Little, C.C.
Laric
Seltzer, Carl C.
Jones
Fisher, Ronald
Stamp, Josiah
Harlan, William R.
Bowden, Alfred F.
Ochsner, Alton
Heller, John
Hockett, Robert C.
Gray, Bowman
Glenn
Allen, George V.
Zagurski
Hager, Virgil
Cullman, Joseph P., III
Pearson
Sommers, Sheldon C.
Anderson, W.A.D.
Millard, Max
Moss
Kotin, Paul
Stewart, William
Moore, George E.
Judge, Curtis H.
Kornegay, Horace R.
Burch
Hart
Horrigan, Edward A., Jr.
Hatch
Sommers
Adler
Shields
Warren
Rosenblatt
Dannemeyer
Witt
Mine, A.
Type
draft
outline
compilation
press release
deposition
statement
Date Loaded
08 Jan 2003

Page count mismatch (files 147, split 153)

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Page 1: 282005050
2S~005050 Subject to Claims of Privilege and Confidentiality: Produced Pursuant to Court Orders In State ofMinnesota~ et al. v. Philip Morris, et al.
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[Draft of 3/14/85! TOP.IC: CAUSATION ISSUE Deposition of Robert K. Helmann in Green v. A__T (11/2/59) at 73-77, 81, 98-100, 102-103, 106, Have you ever heard that the surgeon general, Leroy Burney, of the United States Public Health Service, has commented on the question as to evidence or lack of evid- ence with ~espect to the relationship between smoklng and lung cancer? A Yes. I have heard of such comments. Q What has been your position with respect to his comments? & Well, the Surgeon General has made comments at various times. And he has pointed out that there are many fac- tors suspected of being implicated in lung cancer. One of them that he went out of his way to comment about is air. pollution, as being a suspected factor. The general impression T get, trusting to memory, is that he has made a number of statements, a number of possible factors. Q Has it ever been your understanding that his posi- tion is that the weight of the evidence was increasingly pointing In one direction, and that is that excessive smoking is one of the causative -- and I would underline the word "causative" -- factors in lung cancer? A I really don't remember whether he stated it as possibility or in some other fashion. Q I see. Has there ever been brought to your atten- tlon the fact that there was a study group on smoking and health composed of scientists of the American Cancer 2~2005051. Subject to Claims of Privilege and Confidentiality: Produced Pursuant to Court Orders in State ofMinnesota~ et aL v. Philip Morri% et al.
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Society, the American Heart Association, the National Cancer Institute and the National Heart Institute, which their concluslon was -- Q -- in which their conclusion was: "The sum total of solentlfic evl~ence established beyond a reasonable doubt that cigarette smoking is a causative factor in the incidence of human epider~oid carcinoma of the lung"? Has that ever been brought to you~ attention? A Yes. It has been brought to my attention. Q And what was your position with ~espect-~o that contention? A My personal position? Q Yes, with respect to that contention. A I believe their statement is based on fallacious evidence. 0 With respect to the British government, has It ever been brought to your attention that they have dis- tr~buted posters based upon a report o~ their Medical Research Council, * * .* -- stating that the relation- ship between cigarettes and lung cancer is "one of direct cause and effect"? A I have read reports of various kin~s of action f~o~ Britain, some ~Isputlng the theory that you speak of and some espouslng it. O I am speaking about it being the Brltlsh-govern- ment's view, their Public Health Service. Have you ever heard o~ their position with ~espect to it? A I can't be certain whether what I read -- whether what ~ read was from the British government or from some private a~en=y. 2S200S052 Subject to Claims of Privilege and Confidentiality: Produced Pursuant to Court Orders in State ofMinnesota~ et aL v. Philip Morris~ et al.
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~) Let me put it another way: Are you aware that the British government has taken a position, that is, their Public Health Service has actually taken a position with respect to this claim of cigarette s~oking an~ lung cancer, one way or the other? A Well, my answer would be the same as before: that I don't know whether it's the government or some other agency that has taken the position. Q An~ you don't know which way the British govern- merit has gone, either for it or against it? A No; I don't. Q Has the work of Dr. Hammond in the work of Hammond and Horn on statistics for the American Cancer Society and their study on some 187,000 men and their conclusions with respect to smokln9 and canoer ever been brought to your attention? -~ A Yes. Q A~d what is your view of that? A~ I have studied that very carefully, and it is my personal opinion that that is fallaclous, that that study is fallacious ana its conclusion is fallacious. Q The work of Dr. Wynder at the Sloan-Kettering Institute For Cancer Research, with respect to experl mental animals and the production of cancers in them through the use of tobacco tar, have you ever heard of that? A I have heard of Dr. Wynder, and I have read reports of some of his work. And what is your opinion of his reports, Mr. Helmann? A His reports have not been confirmed by others doing simllar work, but in any event it's my opinion t_~hat what he has done and published along the lines you described is not relevant to the theory that we 3 282005053 Sub|ect to Claims of Privilege and Confidentiality: Produced Pursuant to Court Orders in State ofMinnesota~ et aL v. Philip Morris, et aL
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O Has it come to your attention that nicotin~ has been credited with or claimed to have been credited with having an effect on the cardiovascular system or the heart or the blood pressure? A I have read arguments pro and con o . O With respect to the New York World-Telegram and Sun's quotation from an editorial wherein it is quoted: "A relationshlp obvlously has been drawn between cigarette smoking and the incidence of lung cancer, but we have yet to hear anyone offer evidence that moderate cigarette smoking per se is a cause of lung cancer0" Do you have any quarrel with that? A The anwser is, do I quarrel with this? Q Yes. A The answer turns on how you can construe this word "relationship," which has been much abused, that is, if you said that somebody had compiled some statistics in such a manner that a relationship had been drawn, well, then, you could say that a relationshlp had obvi- ously been drawn. On the other hand, the interpretation of that supe'rflclal-"~'elatlcnshlp is completely -- is a completely different question. So there wouldn't be a tendency to quarrel with one word in an editorial which makes a point not related to the point you described. Q Sir, let ~e see if this is a fair unders~andlng of your position -- and I am now quoting again from Volume I, No. i, from the Washington Evening Star article in t~hat: 2S200~0,~4 Sub|ect to Cla~m~ of Privilege and Confidentiality: Produced Pursuant to Court Orders in State ofMinnesota~ et aL v. Philip Morris, et al.
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"Nevertheless, regardless o~ all such reservations, the general picture looks disturbing enough if not alarming enough to warrant the most comDlete ty.De of contlnuln~ study. This is a ch&11enge not only to the tobacco industry but ~o every government agency charged with the safeguarding of the nation's health." First Of all, do you feel that it is a fair statement that there is a challenge to the tobacco industry and also to every government agency w~th respect to, shall we say, the allegations or claims of the zelatlonship between cancer and smoking or excessive smok Ing? A I would say there is a defln~te challenge to improve the quality of the research and the methods being b~ought to bear on this subject. _= 0 Has it been brought to your attention that the claim is that it is the tobacco tar which is the carclno- genlo substance? A.. Well, the word "tar" is a misnomer. ~f you are talking about smoke solids, that is I think what is generaly understood by "tar," although, as I understand it, no precise definition of tar has b~en agreed upon. Of course, tar as such is not specific to clga retie smoke or any other kind of smoke. But ~ have read a great deal about it. Yes. I have read a great deal about so-called tar. Q All right. Zn other words, ~t has been brought to your attention that the so-called tobacco tar is the incrlm~natlnq substance, the allege~ ~ncrlminatlng sub- stance or clalmed to be the incriminating substance? A People have ma~e -~ • .-- Q Has it ~een brought to your arrant(on that there is some claim that the carn[nogenlc substance is in the tobacco tar? Subject to Claims of Privilege and Confidentiality: Produced Pursuant to Court Orders in State of Minnesot,% et aL v. Philip Morris, et al.
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A I have noted such claims. Q Has any attempt been made by you -- and by "you" I am speaking of you as an executive in the Ameclcan Tobacco Company -- to reduce the amount of tobacco tar? * * * We are talking about Lucky Strikes. A Well, the mere fact of certain alleged character- iStlcs of so-called tar is one thing. Now, our position Is that the smoke solids and cigarette smoke are the elements that contribute to the pleasure and enjoyment of smoking. To my knowledge, no one has established what are the carclno~ens that cause lung cancer, nor, to my knowledge, has anybody established that such things are present in cigarette smoke. Q Have you had any conferences with ME. Hanmer with respect to any research he may hay8 done o~any feelings he may have on this particular question o~ smok- Ing and lung cancer or smokln~ and cardiovascular disease? A Yes. ~ How often have you ha~ discussions with him? A Well, my contacts with Mr. Hanme~ are not on a regular basis. He~s in Richmond and I'm in New York. O I mean, does he come up perlodIca11¥ to discuss, shall we say -- A .No. Not for that purpose. Q Have you ever had any meeting where it has been confined to, shall we say, the discussion of clalms of smoking and lung cancer and smoking and cardiovascular disease? A Well, ~ don~t believe we ever confined ourselves to that one subject. It has ~een discussed alon~with a number of other business matters that we have occasionally discussed from time to time. * ZSZ005056 Subject to Clslms of Privilege and Confidentiality: Produced Pursuant to Court Orders iu State ofMinnesota~ et aL v. Philip Morris, et aL
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Deposition of John Alexan~ec Crowe in Green v. A__T (ii/2/59) at 4, 9-12, 15, 19-20, 31: Q Hr. Crowe, in the past ten years or so, le~ us say, have you heard about the claims that there has been some relationship, that is, a claimed relatlon- ship between smoking and cancer? A Yes. 0 Did you know, sir, of a study group compose~ of representatives, that is, scientists from the American -Heart Association, the American Cancer Society, the National Heart Institute, an~ the National Cancer Insti- tute, who studied all of the foundations and the litera- ture and observations with respect to this question of smoking and cancer, an~] then came out with a statement to the effect that -- -~ O (Continuing} The quotation is : "The sum total of scientific evidence estab- lishes beyond a reasonable doubt that cigarette smoking is a causative factor in the rapidly increas- ing incidence in human epidermoid carcinoma of the lung." -Did that statement ever come to your attention? A This is the first time, ever. Q ~Sir, did it ever come to your attention that the British Goverr~ent had, after a re.port was issued by the Medical Research Council of the British Government, sta~ed publicly ~hat the relationship between cigarettes and lung cancer is one of direct cause and effect? A No~ I haven't. -- Q Let me ask you, sir, whether the statement oE the Surgeon General, Dr. Burney, as follows, ever came to your attention; 7 ZS2005057 Subject to Claims of Privilege and Confidentiality: Produced Pursuant to Court Orders In State ofMinnesota~ et aL v. Philip Morris, et aL
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"The Publlc Health Service feels the weight of the evidence is Increasingly pointing in one dlrec- t~on: that excessive s~okln9 is one of the causa- tive factors in lung cancer." has not been bcou~ht to ~ attention. Q Do you know if they [TIPS] are attempting to inquire as to the validity or non-val~dity of a claimed connection between smoking and cancer? A Z .imagine they are, certainly. Q ~n that respect, are they doing any research themselves? A I don't know. O Have you personally ever seen any of the publi- cat~on~ with respect to this question of smoking and cancer that were put out by the A~erican Cancer Society? The papers themselves? Yes. The pa..Ders themselves. A No~ Z haven'to Q Sir, was the followi~ ever called to your atten- tlo~: A statement by the medical officer of health of the Central Council for Health Education of the Tavlstock House in Tavlstock Square, in London, England: "Smoking and Health. "It is my dut7 to warn all cigarette smokers that there ~ now conclusive evidence that they are runni~9 a greater risk of co~tracting oance~ than non-smokers. The risk mounts with the number of cigarettes smoked. Givln~ up smoking reduces the risk." 28 005058 Subject to Claims of Privilege ud Coufideutiality: Produced Pursuant to Court Orders in State ofMinuesot~ et sL v. Philip Morris, et al.
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Underneath that £s: "The Central Council for Health Education, Tavlstock House, Tavistock Square, London." Has that statement eve~ come to your attentlon? A No. Q (Continuing) Has there ever been brought to your attention the accusation that nicotine has an adverse effect with respect to the heart or the cardiovascular system? A Not brought to my attention. O Do you have any personal feeling that it has any effect on the heart or cardiovascular system? A I don't think so. 0 Has there ever been brought to your att~ntlo~ any accusation ~ha~ nicotine has an adverse effect or at least has some contributory effect with respect to cancer of the lug? ~, No o Q Do you have any opinion that it has or has not? A I don't th~n~ so. Q Has there ever been brought to your attention the fact that nlcoti~e causes addiction £n a person, that is to say, that after being exposed to the effects of n£cotine, then they find that they are unable to ~Ive it up? A Z haven't had that expe~ience. Deposition of Edward S. Harlow in Gree...__~n v. AT (10/31/59) at-132, 134-36, 137-38: -= Q Has any specific Investigation been made as a result of the claims that there is a relationship between smoking an~ cancer? A Not specific, no, Subject to Clalm~ of Privilege and Confidentiality: Produced Pursuant to Court Orders in State ofMinnesota~ et aL v. Philip Morris, et al.

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