Jump to:

RJ Reynolds

Ss Nicotine.

Date: 19850717; 19860908
Length: 368 pages
513086859-513087226
Jump To Images
spider_rjr 513086859_7226

Fields

Type
RAW DATA
Characteristic
Marginalia
Site
Record Center
01-16-03-08
Box
Rjr4865
Date Loaded
19 Apr 2001
Named Person
Carter, K.
Cornelius, L.
Simmons, S.
F Lynn
F Karen
Ftc
I Dlr
I Bji
Eudy, L.
Request
Mitchell
Int27
1rfp079
1rfp080
1rfp115
1rfp116
1rfp117
Brand
Camel
UCSF Legacy ID
nbi31d00

Document Images

Text Control

Highlight Text:

OCR Text Alignment:

Image Control

Image Rotation:

Image Size:

Page 1: nbi31d00
~ gO~ 2. 2S3 e•.8Zy 2•obs G g61-D 2.2- R$ o•8'Sa 2.i-27 °-.g7a J,./ Lf I . Fil a.-77U- . 89j- 2. zc~! I - , x y4 s G o.Z~2 7- 2 2 -gs-- g "7Z2f~-Q.._SS ~lleeu, v,at vuhU4 3..cgo o-oZq S • y6 3.iSY s.s~u 3665 D:o3s- ,,,a,Als5, g3 3,/6G l. D.o~3 5 3~- 3.2 30 ,04(o S,a37
Page 2: nbi31d00
7-3r-xs B- i-,I s 'tv Cl m5 Ss 7?4 K- 2• 37? 2-F (f9 (• ~yo 2-tgo 2-7oS Z- / yy 2- 73--> r il I•k3Y z•2$7 2.s1s zI /-`!70 2. f`f3 2 ~c-rv S•n(0 01,291, ~ • 3 1 `)tl 7Xg 0• o3Y v • d 31? G.d3y o-~'f6
Page 3: nbi31d00
fAII ~ I M5 -- 1._43X . /•$7g ss ~2._1-oy 3• 2.9'/ I. sso 3 1?9 q7g 2.$07 o• o./.3s. -_-_$ 5!/ 0• c~. 2 y.? S. 0 3 e•03U' 4y.3a:.& 3, 1$_a _ _s--0. 31 _ r3L S•1zZ 1 S• tZ ~ (L~D _ 9. 3 S6 4 • 3G .70 ~ a • lQc S•o 3- Y' 3 Z = O•63~c < 0.6y ~ -• -.. m co ~u7~ .i5 C~o~s t oLnD .40 ~ 0•b{ _. Q 4,:,-~ ~r Y 3 Z aLo (i-Tr% i,lou. 0 ~ ~
Page 4: nbi31d00
= Z _sq n 12 - I-8c~ z.7as a-ov7 y 6 g _-Tr?- 2-79L p.032 5/. S I "~- I r 9a a- 3~a ~ aas d~ IB ~( S 9 -3_ r. iyl 12 rrs a~ 0(0 O oag ~f •~L --- -r---=~-"--~~ 6S
Page 5: nbi31d00
r ,Ir', -4_r ( . i [I : i r ^ aa.;, .. P. a
Page 6: nbi31d00
a q IC`T "I - (s•`) '!`i" i Q2 7~t ~'tu u~e 5i '7 `1 Wk"f-kl R"- , Q909- l,r~c~ r
Page 7: nbi31d00
7- 23-85 I-s 2 _ .. _ -- ~ T*'1_~. ~._a30 _0,0ab . . _.4~..8loq .J• 518 _a_aqo a_~51 a .b, o14 -`f. 'T7/ 1.5p7 1~ 305 /. 76, e O.Q13 ~, -() 8(f, aL99a 9179 Q 613 5s.1$3 d. 3Sr l 7v 4' 0.611 ~l_111 2.0$r 3Z`1'6 o•v3~ S,_y/3 2.blS' ~ 2Sc o.oZZ ~/•_P~3 (- 3S9 ~2 •o6 ? 2-as(. 0- vrs- 4y. /60 Z . C~ga 2-03c-- o -o33 Y./y3 1•~{z2 2' 33q ( -~6Ss- 0•oZo ~. Zcl S i~fl= ~r96
Page 8: nbi31d00
S I 1'llC~~t r~. IR3 . 4 ciif I rep~ wy,~ ~ T2A_ ~ ~ I•518 a•a4o a, slz Ll~' 1507 a.3o5 I I&•b' ~ I l, y 20 a. L9ya a-q7F .U k d. 3Sr l'7v 4' l . c{ o q 2-o$s' 2- 296 Sl~ r- 3-7Z 2.blS 2-25'c t-s 2 y 2•08? 2-os(. ?16 T~l~s M ~. Trl 4. 0~3 ~ Db~(r c~ e, 13 5, l83 U, 01 ~l. l 11 a.c~3Z S.ql3 ooZ2 yg~i3 G•vlS- I/. /6C) 2 .O'go 2.03~ c9 -033 y / ~/3 2- 33LI ra3 il ~~ = ~s 96 f -~ss-- ~-oZo ~zcil s 4- O.Ic38 ~Ig.b7e} 1~31-$S cl co co i~
Page 9: nbi31d00
7_ 23-X5 M ~ 7QA 6 T~.! 55 . ..1.q(p,F __a._a3o ODO 4 1. 518 a.aµo ~. '7'71 1.6611 a. 305 Y U8~ l, 170 a,Lqya a. Y7Y c~ 61,5 S: I'8,3 /, 515 c-2. 351 I-7w9 U.ID ri 4.111 1~t5 =~ O.o~6 ¢8b3L 4.75i- e (I E,7 x
Page 10: nbi31d00
----- S~- cA Al. U s~o U4•Su~9 . r ac~9 e s• gs . o o ~~ ss f 4 , „ 7 - __ - - ~- --- 9-~-~@~----- ------- - ------ i Q A'15 in5 - b~. QS~~f 1. p- I 1 aQ - ---~5 --- - PU.~LC1~Sd']~-------- ---- TrGn~--- -- .~ - ---~~-Q~ ----- ----------- ------------ -- -~ --~~~-------------- - - -- ~ ---- ---- -------- - - - --- L^ --- - - - F~ w m - co al -------- 00 -13 N
Page 11: nbi31d00
! 0 0 ( r ( CUMULATIVE DELIVERIES --- MGS, PER CIGARETTE SAMPLE I.D. 2A1 # PUFFS PER CIG, = B * CIG PER PAD = 40.0 PUFF # WTPM H20 NIC TAR 1 2.330 .330 .0210 1.980 2 6.650 .810 ,0630 5.780 3 11,780 1.430 .1100 10,240 4 17.050 2.150 .1590 14.740 5 22.980 3.030 .2130 19.740 6 29.140 4.080 .2690 24,790 7 35.540 5,280 .3270 29.930 8 41.480 6,520 ,3820 34.570
Page 12: nbi31d00
~-?M~z076 "S -...-~---- - ------ - _---~---- I l - --- ----------- ----- -- tr B uxn222 jl~ pu,ff__ c~ou•,! _.~. - - - ~~ -~ -- - ~ U - -----.. --- ---._..__a-----~a- -- - _-- - _ - - 3---1 ~----------------------_ _. --- _-1n -- ---~----~D-------- ZrJ~ ---- ---- rv f~ .
Page 13: nbi31d00
1 RyFF ~ tyicc hne &Pad (p4. 7I28 -Uri 1L4_ ~2oZ .1~~_ _ z fk4F ms (f")S .50 9-707 51. 02i4 05r)7 tFS,5 --- j A, T I 24f Tq~ - - -- ~1~{( (Wr } - - . TI~'9F r~c 2 ID o46 3 1~ nv.1.{.d - ----- --QO vJTPM - ~- SS (,4. ?19y _ ~i~' ! R4 F S o - ms 50 .97ti 1 ^____6 LO Z91 ~05 o TI_ P-4 F 65 JZf~9F f+twA M: l(-gr- - ---- c ~ 1 i0 rnA --- Ln aA/5 3 ` 10 pu~{s ---- ~ - w - - `{- ~ ~{{> --- --- - W -- ,nPM {`=i~----__----~~,~--~------ - -- - _- - ----~5 -----~ y ~-~-----~-y~s l ~~ i~_7_---------~--! ~~ F _ !~~ s --- ~S 50. q753 51 ( ) uJ{_ -Lc&,Od._ III ! ~4 F~r~l~ ~--- ILf !K`{flb `. c) .1 --------_1(i_fajjs_---- --- - ~
Page 14: nbi31d00
( t i 0 f c CUMULATIVE DELIVERIES --- MGS, PER CIGARETTE SAMPLE I.D. 1R4F 4PUFFS PER CIG. = 8 # CIG PER PAD = 40,0 PUFF t WTPM H20 MIC TAR 1 .770 .100 .0410 .630 2 2.220 .260 .1330 1,830 3 3.960 .450 .2560 3.260 4 5.850 .650 .3900 4.820 5 7,910 .880 .5340 6.510 6 10.140 1.160 .6890 8.310 7 12.790 1.680 .8490 10.280 8 15,360 2.290 1.0200 12.070
Page 15: nbi31d00
C~c seto,e~av~, ~i ~(,Nl ) -7 -~q 5 3 ~ 0,16Q (3z7~ -J-22 g.2g ± 0,53 (io 7~ 1-a3 ? a# /+,0f 0.W (isgx) cwd ~ , -7z5 Sc~C~ ~te, av& swofu.~e I
Page 16: nbi31d00
7-28-85 }: -~ 10 n~~~ ~ L` --~ e ID 4. 80 a r~S 509'7to~a 51 ~8a~1 IaSR '' SS ~ „ 4 !I ---- ~ 4 10 0 ,r.~. P J ~£~--~t~i 3~~L _ SS c~ 471,55 ~, 58a~2_~ rns 5'1• paoO fb~~ °« ss fuFf T~.p A A ni.~f f ,N ~ T ~ _q ~6~ -.0A i, l kJecla, -_ n~q(r -- 41__W Idt Wt l b ----f2L, a-wuaa---- _~ 1 y-uqs --~---~ ~ --------- _
Page 17: nbi31d00
SS fy(c,ohnk, m t] ,- ___- ~9S 50 - 8'r ' 9 2 0$ I R ' 4 u 5 s T(A 7v f) _-_ rID - ------ ~ r~ ---~iQ__ -~ ~ - rnod. Wn t ------ m5 50. 855~ 50 qu YS:- 1090 nrQ3 m 55 - TrA ------ --- ---2---JU _---- ---- --- --- ~ - 10 ---- --- ~ -- --- - co --- - 4 J~ w - -- - V W - -----(~-~-~----~.~ . -°~- --- -- v~~_--- --~ iD ----- ~`' 5---- - --- ~! ~~-"~-- -----~-_------ ,~. --- -- { ----- ----_ -------- ---- -- ----~---_ _ --r ~- ~d~i1c --T---- _--- _ _-- ---------- Tr /4 -_ . _-~~ - -- -- - 1 - ---- - - _- ~ ----- 4
Page 18: nbi31d00
T-v rr ~ssp js.si, m MV6 Tcfivmk C~- at- (QQ ec, put %bcuwt- c • SAMPLE I.D. 2A1 # PUFFS PER CIG. = 8 # CIG PER PAD = 40.0 ORIGINAL DATA ENTERED FOR 40.0 PUFFS PER PAD ( PUFF-#-.... WTPM H20 NIC 1 93.3 13.1 ,84 2 . 172.8 19.2 1.66 3 205.0 24.6 1.89 4. . 210.9 28.9 1.95 5 237.3 35.2 2.15 6. 246,2 41,9 2.25 7 255.8 48.1 2,32 8 237.7 49.4 2.20 ( ( ( ALL VALUES ARE IN MGS, CALCULATED DELIVERIES --- NGS, PER CIGARETTE SAMPLE I,D. _~ pUFF9,PE_R CIG, _' 8 # CIG PER TAD = 40A PUFF # WTPM H20 NIC TAR 1 2.330 .330 .0210 1.980 2 . . 4.320 .480 .0420 3,800 3 5,130 .620 .0470 4.460 4 . 5.270 .720 .0490 4.500 5 5.93D .880 .0540 5.000 6 6,160 1.050 .0560 5.050 7 6.400 1.200 .0580 5.140 8 5.940 1.240 .0550 4.640
Page 19: nbi31d00
7-/9-$.S' f iH i Xv O-M~A i,go~r~~--a, ~43 MS 18`I x~ s ~2z G= ~ q7`1 T~ l rwp /3 7;F,~SS 3-291~ o. 0 13 s 5'!/ 3. ~ 2~/ o. 0 2y3 S• 03 2. g 07 0• 0 31s y. 34:.. ? •_a.q9__ -? • 3 !y o- a_z77s- s'•vy 2. J `t r s t~~ ( 5k-..t z2.l~ cf' o•4~ps' o•Y93 p f - 1• a-oo .3. / tS' o. a 30o S~•y/ 3. I8a~ .031 5 3,;z S. fZ o-Yg g•3(O 70 5.3~2 ~ 0.1(09 (3z%0 ov1/~it y~ y u~ &"V~ ~ - QflaC, ~= dlw= C•~) h.~, So3-q'3z 5 Hy-Lr--, .- = D•63 F < O-6 f 0 63y b~~5 Q o t9 r (~'~ ~N1 i^. ~o2v 0 r w m co
Page 20: nbi31d00
~p z A S n' - 6- -5 ~w, w7Pm - -.8-4,& / D - 150, q9icq 6I- o94a o 9_7 __ puF( cr unf T - -~~~-lp --- -- r -~~ - ---- - - 3 (o ----?--~Q-- --- ------ ~--2 -- - 51, OGg3 -------- ----Puff-~o!.`-n~-- ~--~ - ---_-__------- --------- ---------------- -___ ____~_~ ----- -- T - v - ---- - ----- - - - __- ~ ~- - ~o 9 - 10 - _ -- _ ---_~- -- ----- --lr1_~~41___ -_ 44-~857- --- --~ i ~~~s ~J. UU7A -----_ -- - --{~i ~~_C~w~i~___ .. _ ---. __ ---------- ------- ----- - I~ --~---- sv~.1_: J~ - ? iv 3 10 N ~ - W 0 I: .
Page 21: nbi31d00
Interoffice Memorandum To: Dr. Charles Green 8 August, 1985 From: Larry Eudy and David Eaker Subject: Sidestream Nicotine Comparison of Reference Cigarettes Total sidestream nicotine was determined for four reference cigarettes:1R1,1R4F, 1R3, and PD000207 (control for environmental chamber work). Smoking was performed using the "hood" method un- der standard smoking conditions. Sidestream smoke was trapped by a Cambridge filter followed by two isopropyl alcohol traps connected in series. Nicotine analysis was done by GC-NPD. Four cigarettes were smoked during each experiment and a total of five experiments were performed for each reference cigarette. Total sidestream nicotine was calcu- lated as the sum of the three traps analyses. SS nicotine collec- tion efficiency was estimated as: approx. 40% Cambridge pad, 60% Trap A, and <1% Trap B. A summary oy the results are listed below: Cigarette Total SS(mg/cig.) Std. Dev. %RSD PD000207 4.69 0.12 2.58 1R1 5.32 0.17 3.17 1R4F 5.49 0.21 3.86 1R3 5.06 0.22 4.31 O/OaLa~ry Eudy David Eaker
Page 22: nbi31d00
SS C d41r~~ F 112 , 7-22- $y- Ln-!25~ m5 ss T e ` . l --A - T? B_ Toj"Q ss 4•8~7 2. 2S3 3._ r go 0-oLq S • y6 ~ 2.o6S 2•0-7f o- a3S G $~D 2•Zg$ q. 3,o ~ 0•-V,iO. 6.63 • J-1L „ o •8Sa 2.127 366s p:O3S- 5-g3 v o•g7a 3. /b G d• 5. 3 ~C W 8, 1 ~ . 1 a 7 7,2- l.yc~a ~a& vA 6•6214- o. oz7 ~ 0,8Q jl CG[*,bU 7-24-e5 5.213 I s.2g ! o.9q ((l, g 7 ) avVA 1L1LQ S,2Z ~ 0, b'l ^~ NO ~oDd - 5•?$± 0 •5'3 (,o%) 0) co V b
Page 23: nbi31d00
R • F r CUMULATIVE DELIVERIES --- MGS. PER CIGARETTE SAMPLE I,D. 3A1 * PUFFS PER CIG. = 8 # CIG PER PAD = 40.0 PUFF # WTPM N20 NIC TAR 1 1.700 .170 .0100 1,520 2 4,980 .520 .0590 4.400 3 8.800 .950 .1180 7.730 4 12.970 1.450 .1550 11.360 5 17.240 2.010 .1840 15.040 6 21,850 2.710 .2150 18.920 7 26.950 3.630 .2480 23.070 8 31.720 4.630 .2790 26.810
Page 24: nbi31d00
193 wS a7.4'r_•t'. CI SS o'~• l ~0 3 -I r 5{f' ~wr x I. Ic~ r Fi r~ C! a5 : 2 q . 5_5 ~ t °5~ lz~W 1 °;U. 9 4 4.= . 7 4 1 D n ...v_b l .. 50. 9b{I;' 1 " Z
Page 25: nbi31d00
( SAMPLE I.D. IR4F ~ # PUFFS PER CIG. = 8 4 CIG PER PAD = 40.0 ~ ORIGINAL DATA ENTERED FOR 40.0 PUFFS PER PAD .PUFF.#.. WTPM H20 NIC 1 30.7 4.1 1.64 E 2_ . .57..9. 6.2 3.68 3 69.5 7.7 4.91 4 75.5 8.1 5.35 ( 5 82.4 9.0 5.77 6 89.4 11.3 6.18 7 105,8 20.6 6.38 8 102.6 24,2 6.83 ALL VALUES ARE IN MGS. CALCULATED DELIVERIES --- MGS. PER CIGARETTE SAMPLE I.D, iR4F -`_VPUFFS PER CIG: = 8 # CIG PER PAD ='40:0 PUFF # WTPM H20 NIC TAR 1 .770 .100 .0410 .630 2__ 1...450 .160 .0920 1.200 3 1.740 .190 .1230 1.430 4. 1.890 200 .1340 1.560 5 2.060 .230 .1440 1.690 6. .2 . 230 .280 .1550 1.800 7 2.650 .520 .1600 1.970 8 2.570 .610 .1710 1.790
Page 26: nbi31d00
Physicat Data CRW gmJ cig RTD cm of H20 Static Burning sec/40mn Length mm/ cig Circ. mm/ cig Paper Porosity sec150cc Paper Additive Type % 1R1 1.120 7.4 552 85.0 25.11 47.6 Phosphate 0.16 2R1 1.184 8.9 660 85.5 25.0 47.6 Phosphate 0.16 2R1F 1.094 13.7 642 84.9 25.1 47.9 Phosphate 0.16 1R3 1.152 5.9 414 85.0 24.8 21.0 Citrate .50 1R3F 1.066 13.0 438 85.0 24.8 18.2 Citrate .50 lAll 1.066 7.6 450 85.0 25.07 47.6 Phosphate 0.16 2A1 1.150 7.4 582 85.4 24.9 46.1 Phosphate 0.16 3A1 1.183 5.8 564 85.0 25.0 34.6 Phosphate 0.18 lA2 1.174 8.1 468 85.0 25.12 4.7.6 Phosphate 0.16 1A3 1.168 9.3 492 85.0 25.03 47.6 Phosphate 0.16 1A4 1.158 8.6 522 85.0 25.07 47.6 Phosphate 0.16 1R4F 1.072 13.8 552 84.0 25.0 22.0 Citrate 0.80 lstock is depleted Abbreviations: CRW - cigarette rod weight RTD - resistance to draw Circ - circumference 6
Page 27: nbi31d00
-3 J_~4_.F_ -. ---------_ _---------------- 7~~~`----- w ., .-. C)5D5 YIIR4f _m~_- - - -- S'S- (p4 640 (Ly &;~? -_ 15(c "7 " ` 65 - -puff-LAMt - - --------- ---- - -11_ Purls ----- - - _..----------- y- --- ---lL-IgUYs - --- - -- -- - - ----- -- -- 7_a cD -LC URP,M P . ..-J v_. ~ ----- --- _ - -- --- _ --------- - t' m 00 o+ Ln
Page 28: nbi31d00
FJD CY-O~) z°-7 sff ~~ h ~- ~S s 7)? 14- `772 13 '25 s's _ - A~-- 76 S b•_°_~---~-~ g- --rTTl•975- 2• 79Z p•o3~_-~ 8 I ~- -~ a. id- S_- 6 " ~?--_1_? I - -~ --- --
Page 29: nbi31d00
( SAMPLE I.D. 3A1 4' # PUFFS PER CIG, = 8 # CIG PER PAD = 40.0 _ ~ ORIGINAL DATA ENTERED FOR 40.0 PUFFS PER PAD PLLFF. # . . .. WTPH. H20 NIC 1 68,1 6.7 .38 ( 2 131,3 13.8 1.96 3 152.9 17.1 2.35 4 . . 166.7_ 20,0 1.46 ( 3 170.7 22,2 1.16 6 184,2 27.9 1.25 7 204.1 36.8 1.32 8 190,9 40.0 1.25 ALL VALUES ARE IN MGS, CALCULATED DELIVERIES --- MGS, PER CIGARETTE ( SAMPLE I.D. 3A1 # PUFFS PER CIG. = 8 # CIG PER PAD = 40.0 PUFF # WTPM H20 NIC TAR 1 1,700 ,170 .0100 1.520 2_ . ._.3.280 .,350 .0490 2.880 3 3.820 .430 .0590 3.330 4 . 4,170 ,500 10370 3.630 5 4,270 .560 .0290 3.680 6 .4.610 .700 .0310 3.880 7 5.100 .920 ,0330 4,150 8 4.770 1.000 ,0310 3.740
Page 30: nbi31d00
Qwn.~i PaA L ,1 ------ - WTprf) ~ ~ 1-- saun~. - p {,~ - - _ __ ------ - - --- -- --- - _-_-- ~ - - - ---~ - -- -~~- ~---- ---- - --- ------- ~ 10~ - - - - - - -~ 307,2 -~1 M~ - - ~-1~ I (115 27~ -~~- e I SS -- - - s9P or~s'7 17 -11~L7 _-~-s ~-- -- ------ - _~1(Z ~ ~ ~ ~ ~`~- -- - - - --- - - -- --~ -----1~__~~~ - ~ - tu-e- -- - -- IL --- - -- --- ~- {~"~-- --1~ - - --- ------- ~ Y 9 W ~ W N
Page 31: nbi31d00
Smoke Analyses FTC Method TPM m_g J~cig _ FTC Tar m~q/ci~Nicotine m/cig ~ 2 mml ~0 mm ~ 3~ mm 23 mm 0 mm IR1 40.6 35.4 34.3 30.1 2.16 1.98 2R1 44.6 38.8 36.8 32.9 2.45 2.19 2R1F -- 28.6 - 23.4 -- 1.74 1R3 27.1 23.6 22.8 20.3 1.46 1.23 1R3F -- 18.1 -- 15.0 -- 1.16 1A12 30.9 27.0 27.5 24.5 0.30 0.24 2A1 41.3 35.0 36.4 31.8 0.48 0.42 3A1 33.3 28.80 31.1 26.8 0.27 0.24 1A2 39.5 34.0 34.0 29.5 2.08 1.75 1A3 34.8 29.4 29.0 25.8 1.28 1.14 1A4 42.5 35.3 35.5 29.8 2.61 2.20 1R4F3 -- 10.8 -- 9.2 -- 0.80 Ibutt length 2stock is depleted 335 mm butt length 7
Page 32: nbi31d00
~ J ~ r7-19 45 1 V rv- vl~ , - ---------- -- ---- __~S - - -- -- -------~ --- _ __ -- - --~0,$3~18 ----- ~- cs~.= - ----- ~- c:~ - --- -- ----~'~, 2l_n98 • -- - iD - a d ~ wrvm - p S - - S P IS 5D. ~ 9 rl1 r Kr- ,~a ~ z rI ~ m - - 00 - - 4 AL OD ~ f715 0 . I ! 7 !- ~_ _ (0, (Dq.a io I 1- 2 -- -3 h , --- -------- ---- WTP ~ 54rtt w I -
Page 33: nbi31d00
1R4~~ c~ ~t n~ - . fr 'cc'kv.e ------------- --------- ~JrP C~S 50. 91.5z 50 96 -7a p5ao ~ 1e-4G 55 OuJ4 Cr_y_~ntf ~~l 12qr- Trcp A _ --- ~----~U-- ~ q - ~~-----_ _------ ---. __------ --- 1~ l 2AG Trun PA5 -- ---- ----3 ___lO ~wf~s - ------ ~ - - , - ----- -------- "~~------- ~= - _----------------------- e4F'T~A-- - V~ ..(. - I ~44.21. .______-_____-_- ~ VI -~ 1~ -- - - 00 _ __ -- -_- _ - --- -----___----- -- -- m co -------------- ~ -- ~ - _I R i U.I. ~2QC ( ~`~S 1 }I 1 k 6 . . . _ .. - ......- _.'-?. ....... /.I__/~4:p~JJ~ ... ......... .. ._-_.. .._.... . . . .. _. ._.
Page 34: nbi31d00
04 Smoke Analyses (continued) FTC Method Water m/ci _ Puff count/cic~ ~CO m_g~/cig N_~O~ _m,g~/cig 2 mm 30 mm ~~ 23 mm- 30 mm 23 mm 30 mm 1R1 4.10 3.30 10.8 10.2 2R1 5.36 3.70 12.7 11.2 2R1F -- 3.52 - 11.1 1R3 2.86 2.09 9.0 7.7 IR3F -- 1.88 -- 8.6 1A12 3.10 2.30 9.2 8.0 2A1 4.38 2.85 10.6 9.2 3A1 1.85 1.63 9.9 9.1 •1A2 3.30 2.80 11.1 9.7 lA3 4.50 2.40 10.3 9.1 1A4 4.40 3.30 11.0 9.7 1R4F3 0.90 -- 9.2 11.6 -- 0.34 lbutt length 2stock is depleted 335 mm butt length 8
Page 35: nbi31d00
I_93-_._1~~~- - -_ ~ - 7 31-8 ~,. ~---°~ --- -------- _------ _ ------ ~~~-~ ---------- . -~---~~--n~~b-- ---- --- -----..__._.~----!4---- -------- - p- 1~- --- ~u^'J~ -----{~~~~---- <S.S - --- ---__- ---~-'~-~ -- ~ -~~ - - ~ --- - - - - -----~4_ S 3~------~Q g3 --- - --- ~~~ ~ ------ _--54.~ - ---- - -~~ Ctr-,~=41------ .__----- - -~--- ---- ---- ~ - ----._. _ Z --- -----~---- 9 4 --~3) - - -- --- - -- -----. .---- . . __ -- ---- - -- -- ~wJ _9~zg ?-- ---- P1S ~ - _~K-~ _c.~c~,Li__--------- ._------- __ _ .-- ----------__ _ __ - - -------. ti ___ __ w -- 2- 10 ~ Ln __- -_ q ~
Page 36: nbi31d00
llal, L`_= ~ 41
Page 37: nbi31d00
136a'C£ 9!.iT'0 1b0' 0T b'30'LZ 0000'1: 99'ST ,3;)}:d Sw.JN.C'10Pl.I:fll`J Lf3'6'i: l.,i:5'a 0002'T LG'b'f R:Jo T£0'0 :JNI..LO::I:I:N 1y(ar, ap{ 0041 iJN 1.aN I:! 9W OWON :.;l3bT/£r/L 0'6WIST Qlll SMT IA 1Sb 04tW kar,'G'0 X tdWS/f>uaf3 0 0 T.r,rA 0 T.u4a tib v•,o:I: 3s:,b P'la•!d 5L•36T/£c:/L e:0TQIST g Q (110 'SH4 LA Gb531 1 aTT:.1 !sv,'•,hMt) na.eti
Page 38: nbi31d00
1.43c9, 1.~/71 Qn~c~ .va ; O•b1 S•o3-Y ?Z D•.it9_S` ._6- - s -) n,7.. = 0.(O3'f O..tf Q 3 C• S' ) O-G3~ < O.6y V -7-iy-gS s5 T~x lry l3 !'orF.YSS a.1 Oy 3.26(31 0.0/35- 1• 880 3. 129' o. C) .2y3 S •03 I-y7$ 2.$c» c o3,s y.3 2•0 7 7 . 7.- 3 / y. _.___.p-d_Z_7-S __S^•yy W . _• ! --/. _ . . . .. r m OD m OD kD 0 ~ 3./ts- 0-.030o S'•yl S. r z 4 36 ~o
Page 39: nbi31d00
2 A CFtI_.S 3. : FlN,L..C944,45, *r' FM(.;R L::RR - 0E) ON METHOD FILE GC004S 24 CAI.,.S i : FaN,LE944,45i,45 *R PARAM RANC,E: ERR 24 (:;RL.S 3 : AN,I.-E;944,45i TITL.F::: E3TN]) b!'1', "'iMPL WT; Area Analysis Fi.lrttl..E.944 n) `-) VI iRi OLD f.3ti&f39 7/23/3.9E35 Mthd: 451 Inst 45 Chnl 0 Vial # 0 Stnd/£iMpl X 0.i25 Mthd: A5i VI iRi OLD 09ti9ti8 7/24/i9f:i5 P oak t/NaMe 001 RR'I" SG?.7 Peak HCV MG 0.01 Area 3.&6i3 002 12, 0 VCV 0.02 4.369 003 1219 VCV 0.0i 1.950 004 1.3.1 VCV 0.0i i.AE)S 005i 13.2 VCV 0.02 4,783 006 13.3 VCb 0101 'c?.94O 007 i.3.7 BCH 0.01 3,416 00F:1 1.4, 1 F+CF.+ 0. 03 7.5i7 009 14.4 ACV 0.01 t'..349 0i0 1.4,S Vf.:E; 0101 3.059 NICCI'F'INE f.4 . H BCA 1.89 434.189 03.1 3.5.0 HCV 0.00 3.. i2S 012 i5.0 VCH 0. i3. 3i.48t7 03.3 i5.3 BCB 0.01 :3.32i QIJINCIL.INE:-IB i5.7 ItCEc 0. 13 34.399 014 i , . 9 BCV 0.00 1.274 2.20 54i..333
Page 40: nbi31d00
ss oatt ^ i e3 .ss 2-~ef9 2-7o5 2•23c;~ 1 f q3'r' 1- `t Jo 2•28? 2. ( Y3 2. s 1s 2.-) c-~v 'N S G,o3y 0-0 ~, 6 -r&*X ~~ ( NI ~-) m ~ m w
Page 41: nbi31d00
% i i I If f l , . ~: i, t ~~s l i
Page 42: nbi31d00
s ss a io a ~ q 55 " 2 i, 10 a. 10 .10-Iz 3. /o ,1?34 ID I 3, ia ~ ,_ Nqt 4 1D
Page 43: nbi31d00
>~ I'l~CV~1nJz ) C3 - - - ----- l~ a ~ ca ta __0 n1S _ .50. 60 .~? I~k(~ - ~IR3 M5 _ _ -! i ,~---__ _ --------_ _ 55------ f ~------ - -- v _ - _ l - ------ _ ~S r`"j~ -cuur-a -------- ?__ 1~ 3- JU T(A ss _ _ ... TrA __ _ ~ N w m CD O1 ~ m V - --------- __ _ _------- _ :~ ~ Tr tq
Page 44: nbi31d00
#W affuaw NAet e,ti . eva 6umjma~, ?aol mftwa.~ -6wo ~u~fiLt~ C(00 r+tiQ tse~ewar,ut~( u1 C6M- kaPng , a{.a~ It .~,~~ew-, t~.~Lwa'E~~¢a.+M.. :{u,~~. , e1 _ WWUA,, ptt- YwG„ 4 &6~ ~_met,,' ~OCssc~~- , Suit- w/ I K I ~ 4~ w~ .9~t 0
Page 45: nbi31d00
Aren Anu;ly~•is f'i].i tL.Sr;O S 1.f23 NJ:. i7i02t46 7/23/1985 M-thci : A,~a Tns.t 45 £:hn'i 0 Viu1 # 0 4;Tnd/Snpl X 0,125 M'tiiia t 451 I iR3 i•i£i M 22 :52 7/<.'.3/198r:i Nome MG t'k RRT RRF Areu Height 001. 0.01.1 I+CV 12,74 1.0000 2.852 0.902. 00'i' 0.0i2 VCV 1.2.78 1.0000 3.120 0.893 003 0.004 VCV 12.95 1.0000 1.068 0,20S 004 0.0i5 VCV 1.3.19 1.0000 3.954 0,f370 00S 0.007 VL:B 13.33 1.0000 1,908 0.653 007• 0,006 DCEt 13.66 1.0000 1.690 0,511. 007 0.025 IiCE< 14.10 1.,0000 6.57Q 2.592 000 0,009 I{C1I 14, Ci0 1.0000 2,371 0.591. NICOTINE 1..464 HCkt 14.76 1.2000 320.75S 145.098 00CI 0,0135 BCB 1.5.03 i.0000 22.248 9.727 QLJINI]LINE-!I£; EiCB i5.66 1.0000 32.865 i4,1.53 0i0 0.004 D£:V 15,91 1.0000 1.064 0,336 1..767 400.472
Page 46: nbi31d00
S~ I'llCp{111C, 1 l3 Ij i, ~~ m~j -~ ~- a.a3o ~ a.a4o 1~.1 1.5p7 ~. 305 ~ Y d- 35i lu k r•~fo~f I-S ;6 = o.~? s3)-- : q p) 3 D -7. 23' 05 2-oS6 0 - CDI57 ~(. /6d c~-O33 y. ~y3 C9-oLo 4 / Z`K /c 2-03~ W. Sk-r,(
Page 47: nbi31d00
-X a Ar•ra FttrcrAy •ls f'ia.i. ~l.l"9h6 VI .'rR1 OL.T) 54127;u4 7/23/1985 t+thc; ; 4M. J:i st 45 Chrr7. 0 Vi.ra1 # 0 Strtd/5M(,I % 0. 125 Mthd: 4ri. V7: IRI C1L.D 14;47:4:1 7/23/198':3 Nur.ws MG Pk RRT RRF Ar•en Wei.ciht (i01 0.01.7 VCV 12,1.6 1.0() 00 4.368 1..20f: 0l)S:, 0,010 VCV 1.2.25i 1 0000 1 .'.397 0.844 003 0.(111. VCV 12,34 1..0000 F:!.798 0.768 004 0.014 VCV 12.42 1.0000 1,.5£li3 1.392 (10"; 0.0r;0 VCV i2.S3 1.0000 12.546 3.856 0(1f.. 0.02(1 VCV 1.29 a9 1..0000 5. 071. 1.749 (10'7 0.033 VCV 12.72 1.0000 8.i'l8 2.278 004, 0.049 VCV 12.77 1,0000 12.180 4,874 009 0.022 VCV 12.84 1.0000 5.493 1. ,95'7 ()1.0 0.01.2 VCV 12.94 1,0000 2.964 0.710 011. 0,087 V(:V 13. 08 1.10000 21.626 7.787 01~~ (1.077 VCV 13.19 1.0000 19.145 5.489 0i3 0. 005 VCIV 13.35 1.0000 1.277 0.41.0 0i4 0,011 VCV i.i.43 1.0000 2.812 0.862 015 0.09.2 VCV 13.49 110000 3.074 0.8Ca7 011, 0.1114 VCV 13.66 1,0000 3.390 0,604 t117 0.004 VCF+ 13.75 1.0000 1.108 0.525 OS.O 0.014 krCV 13.99 1.0000 3.5SiY 1.qir5 03.9 0.044 VCV 14.10 i.0000 1i.111 3.61.7 020 0.0i8 VCV 14.~.'4 1.0000 4. 508 l..22;i OR'i 11,01.4 VCV 14.37 1.0000 3.0.2 0.931:' 02l' 0.0131. VCV 14.49 1.0000 5.190 1.923 023 0.031 VCV 1.4.54 1.0000 7.771. 3 .417a () G'4 0.007 VCV 1.4.63 1.0t100 1.784 0.525 N]:C(:177.NC• 3.18C.'. VCV 14,76 1.2000 662.428 290.912 02c: 01081 VCV 15 . 0':X~ 1.0000 20.348 4.477 026 0.022 VL"V 15.11. 1.0000 5.422 1..031. 01?.% 0,032 VCV 15,22 1.0000 7.966 3.500 0128 0,01.7 VCV i5,34 1.0000 4.161 0.689 0i:?9 0.026 VCD 15,48 1.0000 6.502 2.761 Qt.l]:NQL.:I:NE1-•IS E+CB i5.66i 1.0000 31.231 14.102 030 0.016 BCV 15.91 1.0000 3.96(l 1..112 4.098 891.371.
Page 48: nbi31d00
rtat Ur1deI',~TQ6C1 30 [aal..fp fI t C:NI) CA[..5 SS i A Po l nu .!. rea ys I ' 1. .l, (' 1 L.L.ri'4 C', V:f iRi GL.1) 13:52:07 7/23/19135 rl •fhU 1 1 !'1j Inst 4~3 Chn:[ 0 Vial 1 0 f>tnci/5ropa. Y 0,iL'S 14flid: 451. VI iRi pL.I) f.4ti2rl.4 7/23/i9f3'::> Nurte 00s. N(:. 0.006 PI< I:;(::10 RR7 RRF 12.52 i. 0000 Area Height 1.700 01292 0(3P 0.062 I3CP 1,2,77 1.0000 19.233 7.2H5 003 0,01'7 F.{CEr 13,16 i,0000 5.200 1,.346 004 0,009 I3Cli 13.67 1.0000 2,830 0.636 0 fi':f; 0, 019 £;CEr 14. 10 1.0000 6.003 2.>96 00(, 0.00"ur Lt[:V 14.3E 1.00O0 1.024 0.300 007 0.008 VCV l.4.6iS f.,0000 2.331 0.496 NI(::(iTIN[` 2.103 VCB 14.76 1.200(1 ,40.6':x6 23k'3.7S.i3 00[i 0.13f. I:;CV 15,03 5.. 0000 40.466 16.231 009 0, 005 VCV is.23 1. 0000 1,506 0.7f.7 os.0 0.0f.Ii VCV 15.3'a 1.0000 4.692 1.360 01s 0.033 VC.Ir 15.4(3 1,0000 M030 4.301. 0 1./1N0L.INC-l:c3 1F1CV is.66 1. .0000 3E1.566 il>.367 OS.;' 0.0f.i VCV 15.92 1.0000 3.277 0.865 2.547 677.574
Page 49: nbi31d00
P-/9b'5 l~ ~S N`~cuEine___ B~ _J D_ __ W TPni -A* C,x",,t - 64 I___ _'. _JJ--p cA ~ d - __ 11, p4e ._ _ - - - Pj.,n L2 - Par1l uA 55 [Y15 fb__._I _t R1-_NS-__._ 21z ~0 0. 3a39__ -L)59.y _1300 ___~ _LR! "f!cyA_. 1.1- lpu-_rms_____ 9 zI _. rKr-_Tr~pa_ -JL ~ L w 1~ ~ w * .P _._/CQ -PbLliv. - Il pl* --- m OD m OD W J a . ... ... ..-(JU.ft .lA(` . /?1s ss _ __-- ~`'.~~ z . ._ ._,I P,44'_ -1 - _I 21.- 7rty & _- Wtorn ,. SCYJLJ~.?- ..!_3'7Y ~II__tkt r~s -, 1U-_31 - -a _..1kI ,~
Page 50: nbi31d00
Ar•er,A Fttrulysis f..i.O i LL::'i'4f; STD':; X NG i5;38;30 7/G3/1905 MOc;; 4Si :Lnui 45 (:hnl 0 Vi.al 4 0 Jind/.'irepl X 0,500 14Od ; 451 STDS .5 MC i5;55;55 7/23l19£i.i Nar;e> NG; Pk RRT RRF Area Heiyht N]:COT]:NL: 0,457 BCB 14.76 1,2000 20,693 9.171. QIiINOL..INE:-Tf; BCB i5.66 1,0000 27,i65 12,167 0.957 47,858
Page 51: nbi31d00
7- 19 -w ~2 f ~o , 9 v wn, pud ~~-- >~ ------ 55.---- _-~ {?~~~au cu~~~.__ ______..-----------------------_.__-------- ----~--1~21~"y~A_ ? _ 11 Vu4rall - ~ I . . _c..9 _- - _ _---- ---- - qy:>ti__ I l ~,A~' _ _ _ _« ~ Ll-ql~l ._ _ - 54r o+q 5-1 _ --- -- -------- ._-~ _~1_T~-~l. - ~ __1IZ 11ru~ ~ Ln - r w m 00 m OD 00
Page 52: nbi31d00
f4r'Pf! AttICA7.y5.d.S. f...i.a.i :I. L::M I iR3 TRU 1(3: 49:09 7/?3/19L35 Mrhd; 45:;1 In:•,t 4S Chnl 0 Vinl t 0Stnd/fironl "/. 4,135 Mehd; 4551 I 1R;.3 TRIi 5.9;09;1"i 7/23/190S P•k.,r« t1G Pk RRT RRF Area Height NICOTINE 0,020 BCB 14,77 1.2000 3,503 1,40E1 QU:INC11...:CNM:C5 B(:D 15,bfa 1.0000 26.326 1.1,90u; 0 .145i 29 - WO
Page 53: nbi31d00
P. Hreu (ruulysi.!. F 'i1e: ;L[:5'S4 :[1 iR3 M : 19i r'.'.4t 3':; 7/23/1985 MOc; ; 4G.1 1nst 4S CPinl 0 Vial i 0 atnd/5np1 % 0,125 t9rlid; 45.i. 11 1R3 MS f.9;44;42 7/23/19t3:i Nurle MG Pk RRT RRF Ar•ea He.ight 0ti5. 0,004 VCB 12.04 1.0000 1,216 0.420 002 0.010 T4CV 12.73 1.0000 2,8E18 0,856 00:.~'i 0,01c'. VCV 12.70 1.0000 3.326 0.884 004 0.004 VCV 12,94 1,0000 1,147 0,205 00~i 0.012 VCV 13,19 1,0000 3.445 0.731. 001. 0,004 VCIi 13.33 1.0000 1.223 0.454 007 0.008 BCD 13,67 a.,0000 2102 0.695 00E"I 0,024 BCD 14,10 1.0000 6,7E4 2.9fa5 009 0.003 }sCV 14,38 1.0000 0,826 0.292 010 0,00f3 VCB 14,50 1,0000 2,357 0.745 NICOTINE 1.51E3 PCV 14.76 1.2000 352,302 155,781 01.5 0,102 VCB 15,03 1,0000 2£1,339 11,276 01.2 0,006 BCD 15,34 1.0000 1,731 0.298 QUai40L.1N1:'::=:[f3 BCD 15,66 1,0000 34.816 i5,474 1.842 442.582
Page 54: nbi31d00
1>3 - _ 6 1 ~ ° 00 4'35~_ 12 ~~. - - - --- ~~04 ---?.---- - ------ _ _.._.---------- A `~~'`~ ~'T~-'~n _ -- ---~ _ --- r})~ ? to ___------.------- y ----
Page 55: nbi31d00
I Ei:), ( CL~:fi,{a<u.ua, ) ___ ( l~~i.., Il -.L"_31" ?j- ~~~~~~u r Z?~(~? W7~'~ C ~y 1 [G p!-cas- _ _ . ' lb PIO .fU , __- r~,~S ti~~ ~ _y- po~t, Ct,u,i,{_ _ --d--D-q DA - _ _ .~ V ~~~SS,,..../ .... ... S._"_ ..._._.. 2 (Q ._ __.
Page 56: nbi31d00
Area Finaly<..-1s ('.i.li: : LL::'i57 11 1R3 TRTi 21;S07Sr6' 7/23/A9i3S M06 ; 4M InO 45 Chnl 0 Vial # 0£ind/Sropl Y. 0,125 Mthd; 451 11: f.R3 TRfi 2f.;31;05 7/23/19Fa'3 Name hiC~ Pk RRT RRF Area Height NICOTINE 0,019 DCFt 14.70 1.2000 3,2l.3 0,960 QLIINUL.INU=Iia BCb 15,66 5,0000 25,225' 11.223 0.144 2 8,4M12
Page 57: nbi31d00
Area Ana].ytds F .i.1.r::: l..k:99; 3. :I: iR3 S]i 17t38l12 7/23/198ei Mtlici o 451 :Ci wt 45 Chnl 0 Vial # 0;1rid/Srop1 % 0.125 Mthcit 451 T iR3 aS 17; 58ti9 7/23/1985 Namw MC i`k RRT RRF Area bieight 003. 0.008 DCV 12.54 1.0000 2.671 0.553 00" ' 0.065 VCTi 12.77 1.0000 21.890 8.b05 003 0.024 FsCV i3.i5 1.0000 8.112 ".',051 004 0.007 VCV 13.44 1.0000 2.191 0.41f) 00S 0.005 VCV 13.50 1.0000 1.715 0.399 00i.• 0.014 VCV 13,67 1,0000 4.F.154 1.251 007 0.007 VCB 1.3.76 1.0000 2.392 0.487 000 0.01:'3 BCF:r 14.10 1.0000 7.751 3.25b 009 0.003 }3CV 14.38 1.0000 i.008 0.i?92 0i0 0,007 VCV 14.55 i.0000 2.482 0.5i4 0i3. 0,002 VCV 14.63 1.0000 0.770 0.280 NIC-OT:CNC:: 2,230 VCB 14,76 1.2000 625.635 272,660 012 0.007 BCV 14,98 1.0000 2.458 0.919 0i':, (),123 VCV 15,03 1.0000 41.409 18.023 014 0.004 VCV 15.14 1.0000 1.292 0.39i 01'_; 0,004 VCV 15.i'3 1.0000 1,446 0,695 01b 0.0f.8 VCV 15.35 i,0000 6.001 i.7i8 017 0.048 VCV 15.47 i.0000 ib.26b 6.595 QUlNC1LTNE-1:!a VC:V 15.fifa 1.0000 42.090 17,316 O1E: 0.0(1G VCV 1.5,78 1.0000 2,069 0.679 019 0.014 VCV 15.92 1.0000 4.863 5..1.27 2.746 799.362
Page 58: nbi31d00
90£'T£ 8£T'0 M'2T Lb8'f3G 0000'T 44'5T i33a SI=::1NI'IONI:fIP] £66' 0 656' Z 000I?' T F1L' bT 338 £TO' 0 ANT.•L(:):]IN *WaH Si36T/£w/L oa,ey TSYSI£2 A21N 1.J21 Id OW U2lL £21T :L I I awoN TSb i P4•tW !.auT'0 X LdW5/Pus5 0 1k LryTA 0 Lu4:7 Sb 1suI T5b ; ny.1.W 586T/£M 9WcV£u U`J•L f•JT II I T'J6::111,1:T.:1 M{tnu11 naAy
Page 59: nbi31d00
9£b' 808 £'TS' b 8c'81 0 902.1 2 O000 1 I I6'51 001.1 9T0'0 0 c30 l.01.' TI Ib8'Sc; 0000' T 99'ST d;7£I :i1~:f"1(7Pl:CfICI iL8'r.: LUT'6 00U0'I 8b'ST f:I3A bb0'(1 /.,i°i) £~N ' 0 f:ak:.8'£ 0000 1 T f34'.'ST Aan f,TO' 0 9dQ i:16T'c' BLSi''ii 0000'T .^c.i:'ST n:]n L'c";0'U '], i:',U £:T6' 0 () b£' b 0000 "t :T' ST nan Sc:O' 0 0 696'k: 8£5'8T 0000'T b0'SG A;:)n 060 0 0 () L2T''.iL"r.' 0ZS'2c',9 Q002'T 9L'bI A;]i,{ bI9'E :1N:I:1.(:):)):il 9SG'2 £69'b U0U0'I bS 'bT 1:1::1A £~.:0'0 () 99i?'T L8E'£ 0000'T 6b'bT nan 910 0 0 T,;O L09'Q S00 ". 0000'T L£'bl' AJA 0I0'0 02,U 866'0 26b'£ 0000'T bu'bT nan LTO'U 5S0 8ET'E 600'0T 0000'I 0T'bT naA obQ'0 010 GIO'T E80'E 0000'T 66'£T Aa13 STO'0 GT(1 LSb'0 u'bb'T U000'I SL'£T aaA LQ0'0 '?TQ 669'0 IbS'£ 0000'I 99'ET AaA LI0'0 !;IU IBfi'0 T9L'T 0000'I 6b'£T AaA 600'U V!Q 905'0 £L£'T 0000'T bb'£T Aakl L00'0 £IO £TF_'b 00T'9I 0000'I 6T'£T qan 8L0'0 'TO 66u'9 LT9'LT 00Q0'I 80'£I nan se0'0 TTQ EEb'0 b96'T U000'I b6'£T nan OTO'0 US0 98£'I LbS'E 0000'T b8'PT naA LTO'0 600 6TS'b 860'TT 0000'T LL'iiT A;JA bS0'0 i30Q OS0'Z 06T'L 0000'T e'.L "cT Aan SE0'0 400 L£E'T 000'b 0000'T 09'r'L naA 6T.U'0 900 2£6'F. TTZ'OT 0000'I £S'cT 030 6b0'0 ':iQO Z:£6' 0 L8S'c 0000' T £b'c!T n::)n £T0' Q bQ0 40410 i'.82''. 0000' T b£'c'.T 030 TT0' 0 E00 299'0 68b'T 8000'T S'u''OI AaA L00'0 ;00 6L1.'0 b6S'Z 0000'T 9T'EI 039 ET0'0 IUO byhTaN ua,tV daa .La?l >Id :)!+! <asartN !~:,86T/E2/l. 6b1 EEtBT U?J.L Ei1T I TS b : p4.t W Sc~T'0 X LdWS/Pu18 0 ~ LnTA 0 I.ti4a St+ "IlI I':i t4' y.}41 S86T/EE'./L UbI£T:BI d81 £?lI I irSikf,3'1~ ''CT.J sr',6'[nury r,a,iH
Page 60: nbi31d00
Areu 6inaly!,is If i:Le eL.L::S'SEi III SR3 MS R it46: 25 7/23/1.9©5 t9thcl; 451 Trr:.t 45 Chn1 0 Via]. t 0 Stnd/EMpX X 0.125 1'f'l•hr.l; 4SSf. III SR3 MS 2c^.10Ero32 7/23/i9l35 NurIe MG C'k RRT RRF Area Height 00i 0.0ii HCV 12,74 1.0000 2,99? 0.919 00? 0.012 VCV 12,78 1.0000 3,230 0,913 003 0.004 VCV 12,94 1.0000 1,0E3? 0.2i0 004 0,OS5 VCV 13.19 1.0000 4.077 0.El74 005 0.007 VCD 13.33 1.0000 1.979 0.637 006 0,006 BCB 13,b6 i.0000 1.701 0,493 007 0.021 FrCb 14,10 i.000tl 5.708 2.539 00C 0,002 DCV 14.39 i,0000 0.S74 0,290 00? 0,007 VCB 14.50 i.0000 1.870 0.506 NTCOTTNL:, 1.507 BCB 14.76 1.2000 344.000 i5f3,30£3 010 0,092 IOCEt i5.03 i.0000 2";.253 10.273 OtS. 0,006 LrCTr 15,3S i.0000 1.696 0,397 (;aUINCri..7:Nf::w-]:S BCB i5,bb 1.0000 34.240 14.932 1.015 42Ci.41S
Page 61: nbi31d00
Fu•ea Wtrr.rlysi. Fi1c.:WL::974 V iR3 TRU 07tM 3f 7/34/ii'E35 P1th6; 45i Inat 4S Chnl 0 Vial # 0 Stnd/SMpI Y. 0.12S Mt•hd ; 45]. V iR3 TR1, 07:33:37 7/24/1985 Name MC; Pk RRT RRF Area Height NICOTINE 0.011 EtCB W7f3 1.2000 1,842 0.6% G1L1ItJOL,INE'=IS BCIt Mbfa 1.0000 :5.34f3 11,366 0036 27390
Page 62: nbi31d00
Area Anr,ilys..i!* f .i.Ii: : L_f:'.9a5 II iR3 ,'',s 20:00:03 7/23/1985 Mthc1 ; 4f.iI. Inc-t 4S Chnl 0 Vial # 0 Stnd/SMpI % 0. i.''.5 Mthd ; 451 lI iR3 SS 20 :20 iif. 7/23/1985 Nar•.e M(a Pk RRT RRF Area Height D(li 0.002 VCD 12,02 1.10000 1.076 0.427 00i' 0.003 BCV 12,3a 1.0000 1.624 0.541 003 0.012 VCV 12.54 3.,0000 6.151 0.869 004 0.067 VCV iP,77 1.0000 34.111 12.346 005 0.003 VCV 12.93 1.0000 1.467 0.270 0 0l• 0.009 VCV i3.10 1.0000 4.527 1.387 007 0.022 VCV i3.15 1. 0000 11.031 ;.r,. 665. D O £:, 0.003 VCV 13.31 1.0000 1.678 0,296 009 0.003 VCV 13.44 1.9000 1.407 0.489 05.(1 0.003 VCV 3.3,49 i,0000 1,669 0.46•4 Of.i 0.012 VCV 13,66 1.0000 6.085 a.,675 0.003 VCI3 13.76 1.0000 1.64c) 0.71fS 0t3 0.00i FICV 13.97 5.,0000 0.693 0.226 054 0,023 VCB 14.10 1 .0000 11 .9112 5, 103 0 ]. Si 0.000 E{CV f.4,38 1.0000 3.912 0.612 011, 11.007 VCV 14.49 1.0000 3,363 1.106 01.7 0,001I VCV l.4.55 1.10000 3.915 1.449 0 10 0,0115 VCV 1,4,62 1.0000 2.401 0.667 01 `;' 0.012 VCV 14,70 1.0000 5.9i3 2.375 Na:C:OTINr:: 2.240 V[:V f.4.77 1.2000 946.935 415.704 020 () ,05.5 VCV 14,97 1.0000 7.457 2,0iEi D~S 0,115 VCV 7.5.(l:.i i,00(10 56.237 23,799 022 ll. 0ill VCV i5. f.4 1.0000 4.809 1..14w~ Di : 0.01f. VCV 15.23 i.0000 5,639 1.747 024 0.024 VCV 15.35 5.,0000 12.344 2.816 D 2~. 0. Dt96 VCV 15. 47 1.0000 28,405. 1.1.093 WUINf1l.:I:NE:=~l:fi VCV i5,66 5.0000 63.416 22.3E?i (1 2 E• 0.020 VCV lS.92 1.0000 10.038 2,1.66 2,>;i2f. 1241.930
Page 63: nbi31d00
8bb'pE Ec".bW 266'L8 S£T'0 0000'T 99'ST 301 8U.:iNi`lONL110 9S6'0 95b'2 000C'T BL'bT Rai3 £TO'0 ]NIlf]JT.N 14br, aH na,ad Jaa lilM Nd `1Sd awnN ril36T/bZ/L Sf: I bT 00 }INl £NT (lI Tsb : P4I ~! ScT' 0 X t'IW5/pulS 0 0 IOTA 0 Lu4J !°ib T,"f T'iV ; l7y.1.4! SE36T/b2/L M45M SJl E4T AI ;9;:71"LT.:1 ,rI6Touij riaJd ,r
Page 64: nbi31d00
Areu Ftnuly..is F'i1F;LC::,6~.? IV 1R3 PSS 00; 08 112 7/24/1985 MthJ ; 411 In<;t 45 Chri1 0 Vial € 0 5tnd/Sropl `/. 0. 125 Mthd; 45a. IV 11't3 M3 00i28;1.9 7/24/1905 Nur•.e MG Pk RRT RRF Area Height 001 0,020 VCB 12.03 1.0000 4.970 0,402 002 0,008 BCV 12.74 1.0000 2.140 0.71S 003 0.009 VCB 12.78 1.0000 2.173 0.711 004 0.009 BCV 13,20 1,0000 2.210 0.686 005 0.007 VCR 13.33 1.0000 1.720 0,628 006 0.006 8CH 1.3,67 1.0000 S.S52 0.493 007 0.022 BCR 14.10 1.0000 5.531 2.440 000. 0,003 BCV 14.38 1.0000 0.835 0.296 009 0.008 VCB 14,~a0 1.0000 1.944 0.478 N:I:C:OTIN[: 1.470 BCH l,4.7b 1.2000 309,056 135.61.1 03.0 0.097 BCB iS.03 1.0000 24,421 9.714 QI.IINOI..INE::==Ifa HCIi iS.b& 1.0000 31.54;3 14.077 1.783 388.097
Page 65: nbi31d00
Areu Fsrlcrlya•is t.9 ':;9 :f:C:[ iR3 E:;;;', 22:u1:53 7/23/i905 1rlicl: n,i. :fn<Wt 4S Chn1 0 Vi,al 4 0 5trrd/Srop1 X 0,125 F'iI hd ; 453. :CT:f. ifr3 ::i;i 2."•':4c^:00 7/%'3/198"•i Nr.1me DoS. MC., 0.003 P k VCB RRr 12,03 RRF 1.0000 Flreu 1.2f.0 He.fc,9ht 0,460 OO"r1 0.005 HCV 12.34 1.0000 2,357 0.364 003 0.013 VCV 12.54 1.0000 5.511 0,790 004 0.064 VCV M 77 1.0000 28.255 9,983 0 05 0.003 VCV 12.93 1,0000 f..M 0.226 OD6 01009 VCV 13.10 1.0000 3.819 1,201. 007 0.022 VCE+ 13. 15 J.10000 9.81.9 3,386 00E: 0.003 BCV 13.50 1.0000 f..126 0.398 U0;' 0.01]. VCV 13.67 f..0000 4.630 3..197 010 0.00';3 VC:H 13.76 1.0000 1,508 0.721 0J.1. 0.023 F<C6 14.10 1.0000 10.186 4.493 01.°c' 0,009 BCV 1.4,3F./ i,0000 3.765 0,600 0].;.T 0.013 VCV i4.55 1..0000 5.729 1.104 N7:C,QTTNC 2.305 VCV 14.77 1.2000 641.794 357.199 0 14 0,016 VCV 14.97 i, D000 7,090 !. , 877. 0J.'.., 0,13.2 VCV iS.03 1.0000 48,897 20.010 0 16) 0.010 VCV 15.i5 f..0000 4.370 1.102 01'I' 0,0i0 VCV 15.23 1.0000 4.389 1.401 0 .f l3 0,025 VCV 15.35 i.0000 11.054 2.354 01.4 0.056 VCV 15,48 1.0000 24.458 9.339 IaUl:NGl...:l',N1::::-7:1:1 VCV 15.66 1,0000 54,780 19.8i5 0?0 0.020 VCV iS,92 1.0000 0.71,6 1.830 2, t159 1084 . 657
Page 66: nbi31d00
Area Allaly!.i.t, ("ili;;LE'i'7.'4 V SR3 ti .7 05t27;fi 7/24/f.985 Hthi; ; 4C;i Inst 45 Chn1 0 Vial 4 0 Strid/Smpl Y 0.12':" i4thd t 451 V 1R3 MS 05147; 18 7/24/19Br.; NcArse N(y Pk RRT RRF Area Height 001 0.005 VCB 12.03 1.0000 1.401 0.411 00? 0.050 DCV 12.74 1.0000 2.890 0.902 003 0.010 VCE; 12.78 i.0000 21.670 0.900 004 0.002 I~CV 13.l.0 1.0000 0.583 0.272 00'a 0.0i0 VCV i3.i`'I 1.0000 2.780 0.706 00f. 0,007 VCIt 13.33 1.0000 1.871 0.66(, 007 0.010 BCV 13.68 1.0000 2.B39 0.598 000, 0.031 VCS 14.10 1.0000 8,496 2.923 009 0.004 BCV 14.38 1.0000 1.206 0.360 010 0.010 VCTI 14.50 1.0000 2.862 0,696 N:LCCIUNG. f.,5f.5 BCD 14.76 i.2000 348.943 S5b.3S5 0i3 0.097 EtCH 15.03 1.0000 26,732 11.359 QUI:NQL.]:N&-I:3 BC}:I 15.66 i.0000 34.539 15.462 1.837 437.813
Page 67: nbi31d00
Ar, c>a A malyi:is F.i7.iF tLF::956 II iR3 TRA 20fY.i:31 7/23/1985 Ptth6: 45i. Irist 4F Chni 0 Vial # U Strrd/Smpl X 0.125 Mt'I'td; 451 11: iR3 TRA 20:S5;39 7/23/19f3a NarN e M(7 Pk RRT RRF" Area Height 005. 0.014 BCV 12,16 1.0000 2.946 0.830 00<' 0,008 VCV 12.25 i.0000 1.625 0.668 003 0.0i0 VCV 12.35 1.0000 2,16''7 0.656 004 0.013 VCV 12,42 1.0000 2.620 0.983 005 0.045 VCV 12.53 1.0000 9.437 2,786 006 0.019 VCV 12.59 1.0000 3.885 1.384 007 0,031 VCV 12.72 1,0000 6.434 1.896 001, 0.045 VCV 12,78 1.0000 9,468 3,601 009 0.017 VCV 12.84 1.0000 3.465 i..37i 01.0 0.009 VCV 12.94 1.0000 i,851 0,421 0ii 0.082 VCV 13.08 1.0000 16.972 6,237 01c.' 0.061 VCb 13.19 1.0000 12.661 3.722 013 0.009 E;CV 13.43 i,0000 1.782 0.702 0i4 0,010 VCV 13,48 1.0000 2,064 0.693 0i5 0.013 VCV 13.67 1.0000 2.753 0.535 05.t. 0.008 VCB 13,75 1.0000 1.714 0.343 01.7 0,012 LrCV 13.99 1.0000 2.584 0.917 Oii: 0.039 VCV 14.10 1,0000 8,142 2,387 019 0,019 VCV 14.24 i.0000 3.999 0.837 0J0 0.011 VCV 14,37 1.0000 2.297 0.583 021 0.017 VCV 14.49 1.0000 3.460 1.378 022 0.022 VCL< 14.54 1,0000 4.581 2.035 NICC1TINf ;,512 BCV 14.76 f..2000 435.854 193.094 023 0.067 VCV 15,03 1.0000 13.885 2.883 024 0.0i6 VCV ira.i3 5.,0000 3.250 0.732 0i.:S1 0.020 VCV 15,?.3 1.0000 4.197 1.906 026 0.010 VCV 15.38 1,0000 2.0f.9 0.437 027 0.023 VCfr 15,48 1.0000 4.763 2,036 WU7:NC1L IN[_=IS BCB 15,66 1,0000 26.028 11.393 02F:~ 0.013 BCV 1S.92 1.0000 2.646 0.808 3.298 599,561
Page 68: nbi31d00
`7-2,3-X5 t . 4~ 1 1 tiI CC,ur~i ~ ~ i ~ li~_ puffs -- UL ~ ~ ~ ~~~5------------- -------- 4 r:> > fA~j rtL~__------- .51--U-&2-q-- --- 1C PLJJ,,.),__ I I - Tky ,'. I I )s _ Wrnu 12VI ) ~ • U U C' ~ 1 b - -S5 _---- ~~ p 4 __.Ir~a I
Page 69: nbi31d00
Area lanr.,lye..Ct, F.i.le ; L C:97' V 9R3 ,SS 0602M 7/24/1985 Hthc; ; 451 Ii;ist 45 Chn1 0 Vial # 0;tnd/C,ropl Y. 0.125 1•fthd: 451 V 1R3 63 06t22745 7/24/198i Nur.e MG Pk RRT RRF Area Height 005. 0.007 VCP 12.03 1.0000 2.787 0.A85 002 0.002 DG"V iR .34 1.0000 0.773 0.242 003 0.009 VCEc 12,49 110000 3.302 0.471 004 0.063 BCIk 12.77 1.0000 23.570 9.116 00S 0.009 BCV 13.i0 1.0000 3.319 1.1.00 OOk. 0.023 VCV 13.1.~`, 1.0000 8.447 2.677 007 0.005 VCV 13.44 1.0000 1.925 0.306 000 0.002 VC:H 13.50 1.0000 0.802 0.24Q 009 0.006 BCV 13.67 9..0000 2,047 0.670 010 0.002 VCB 13.75 1.0000 0.858 0.347 0i3. 0.023 BCB 14.10 1.0000 8.548 3.632 07.c' 0.008 BCV 14.38 1.0000 2.923 0.587 05.3 0.016 VCV 14.55 1.0000 5.892 1.106 NICOTINE 2.351 VCV 14.76 1.2000 728.202 320,256 014 0.13'7 VCV 15. 03 i. 0000 50 .964 18.499 09.~, 0.012 VCV 15.15 1.0000 4.275 0.928 016 0.01f. VCV 15.23 1.0000 4,193 1.464 Qii 0,026 VCV 15.35 1.0000 9.671 i.957 01.8 0.058 VCV 15.48 1.0000 21.552 8.203 QU7NCIL.IND-IS) VCV i5.66 1.0000 46.461 15.990 019 0.022 VCV 15.92 1.0000 8.311 1.516 2.918 938.824
Page 70: nbi31d00
('7iE:U (iflc4.1y'.:.i!:> ;.!:'.L0 I':fT iKI3 1I;F 22 i 57i 1.9 7/2:3/1.985 u, i. A a C:Itua 0 Virla. 0 0',:;•lnti/fi;rtKi7. % (1 . 12S litl : 4'::;.i l:I: I: S.T2;; 1 ' 2;'•1 2 3 : 9.7;:2ii9 7/i?3/191ii':i i..f .tr,c Mf:•; 1'k RRT R I:Ir' Ar•crci I{e..i.g1rT 00: 0,0f.q f.tCV 1.2..f.6 1. 0I)00 3.6h, :i. 1.,0'79 0,0(lf, V(::V 1;',33cS :f..0O00 1..'::;F?4 0,66C. 00''. 0,007 VCV 1.2.34 1,I1000 1.790 0,470 0012 0, 0? 4 VCV 1.i'. . 9;' 3.. 0000 '.41. 5..3,T,(, 005 0.057 VCV 12, 133 1.0000 14.269 :.5, J.68 00rl 0,0;30 VCV 12 ,72 s.,0000 7.636 2 ,066 007 0.034 VCV 12,7f:1 1.0000 F3,541 3.2".:'i6 0001 0.019 VCV 12.84 1.0000 4.696 1.,59"J' (10''r' 01008 VCV 12.94 1. 0000 1.956 0,613 09.0 0.083 VCV i3.0O 1.0000 20.821 7.178 0if. 0.0S0 VCV 13.19 5.0000 12.564 3.675 01? 0,012 VCV 13.44 i.0000 2.933 0.766 013 0.009 VCV 13.48 1.0000 2.363 0.751 014 0.007 VCB 13.61 1.0000 1.696 (1.280 015 0.010 EtCV 13.99 1.0000 2.507 0.843 0i6 0.033 VCV 14.111 1.0000 8.201 2.108 017 0.0119 VCV 14.24 1.0000 2.346 0.892_ 03.E: 0.009 VCV 14.37 1.0000 2.172 0.663 01.5' 0.0SS VCV 14.49 1.0000 3.778 1.432 02(1 0.023 VCV 54.54 i.0000 5.679 2.463 NIC[1T']:N[: 1.768 VCV 14.76 1.2000 371.i82 163.996 0{:!S 0,052 VCV i5. 03 1.0000 i3. i37 2,606 0?2 0.013 VCV 15.12 1.0000 3.204 (1.749 02:.Y. 0.022 V(::V i5.22 i.0000 5.493 2.359 024 0.0i0 VCV 15.39 110000 2.551 0.645 02~. 0.09.3 VCEI 15.49 1.0000 3.367 l..2i3 GIUINC)L.]:NF::-Ir1 BCIi 15.66 1.0000 31.494 13.986 026 0.011 EtCV iS.92 1.0000 2.785 0.814 2.461 545.747
Page 71: nbi31d00
.4 Area Analyais F'i]etLk:S':.'.8 II Mfi SR4f S9t23115 7/22/1985 Mthct; 451 Inst 45 Chnl 0 Vial i 0 stna/Enpl x 0.125 MT h d; 45i II MS iR4F 19143121 7/22/i9fQ5 Norse MG Pk RRT RRF Area Height NICOTINE 0,824 BCB 14.76 1.2000 168,107 75.Q50 001 0.042 RC8 15.03 1.0000 10.242 4.421 QI.IINQLINE~;IB BCB 15.66 i.0000 30.584 13,024 002 0.005 BCV 15,87 1.0000 1.102 0,363 0.996 21Q,036
Page 72: nbi31d00
c Area Anulyf.is F"i le : LC.927 I TRB iR4F M47 i46 7/22/i98S tlthc~; 4c;i Inst 4S Chnl 0 Viol 4 0.',tnd/Enp1 X O.i25 Mthd: 4Si I TRB SR4F 19t07iS3 7/22/i9BS Name MG Pk RRT RRF Area Height NICOTINE 0.029 bCD 14.77 1,2000 S.308 2,087 QUINOLINC'-31,', BCB iS.66 i.0000 27.401 l2.2i3 0.iS4 32.707
Page 73: nbi31d00
L0£'£OOT 50£',"r.: OOb'T L94'L 0000'T T6'ST A8A T8O'0 120 064'ST 9061£b 0000'T 99'ST ADA SI=.:3NI"IUNi(1C) 56£'8 b56'W 0000' T l.b'''iT ADA E90' 0 0c'.0 8b0'Z £b0'6 0000'T b£'ST ADA 9c'.0'0 bT0 b6T'T 058'£ 0000'T £Z'ST ADA TT0'0 8T0 T56'0 ST6'£ 000011 ST'ST ADA TTO' 0 GTO £60'9T YEb'6£ 0000'T £0'5T ADA cTT'0 9T0 5L5'T 90c'.'9 0000'T LPi'bT AJA 8T0'O 'iTU '2bT'0S£ L88'L8L 0002'T 9L'bT ADA G69'r. ::1NI1.f.1aIN SbL' T c;8£' b 0000'T 0L'bT AJA c'.T0'0 vT0 5£5'0 888'T 0000'T £9'bT ADA S00'0 £TO 2T0'T £u8'b 0000'T bS'bT ADA bT0'0 ,•:ti0 805'0 8£T'Z 0000'T 8£'bT A8H 900'0 TT0 E60'b 99910T 0000'T OT'bT IIJlI 0£0'0 OT0 9TL'0 T85'T 0000'T 5L'£T }I8n soo'0 600 bs£'T LLO'5 0000'T L9'£T n3n bT0'0 t300 5Tb'0 9ST'b oo00'T OS'ZT ADA iTO'0 100 £OL'£ 992'11 00001 T 5T'£T ADA 220'0 '300 986'0 68T'£ 0000'T 0T'£T A83 600'0 SQO £Te1 8 8951 0c 0000'T !.L'2T F3:19 6''i0'0 000 L8b'0 S05'£ 0000'T 8b'2T 8aA 0T0'0 £00 TSb'0 8Tu'T 000011 S£' 8T n89 £00' 0 ,?00 9E8'0 202'S 0000'T c.0'c'.T 9;]A ST0'0 T00 >•45TM naiv j8N 1d`J NJ `]N zmnN S86T/bu/L 9bf £O: TO u5 £NT AI TSb 1:)4a•w 58T'0 % IdW5/Pu4S 0 4 tnTA 0 I~48 !'.ib ).=uI TSb P'aLb! 586T/b2/l. 6£t£bl00 i::a £`JT AI £96:::1-1:'T?J qp,Alxnuy na,2y
Page 74: nbi31d00
Areu Anuays:.is P-iac;l_I=;64 IV iR3 TRA 0i;i9;05 7/24/1985 Mtht.i; M.;i Inrit 45 Chnl 0 V.ial # 0 Stnd/Snp1 % 0.i.25 M-rhd; 45i TV iR3 TRA Oit39ti3 7/24/i9f35 Nr.ime M(:, pk RR7 RRF' Area Height 001. 0,007 VCV 12.04 1.0000 1.788 0.595 00;' 0.02';4 VCV 12,15 i.0000 6.323 i.505 003 0,0i0 VCV i2.2a i.0000 2.831 0,914 0ll^ 0,0i3 VCV 12,34 1.0000 3.619 1.007 005 0,014 VCV 12.42 5.,0000 3.692 1..456 OOF, 0,044 VCV i2.a3 2.0000 12.i57 3.476 01i'7 0.021 VCV 1.:'..59 1..0000 5,724 3..846 00(i 0,03:.i VCV i2,72 i,0000 8,942 2.564 00C: 0,038 VCV 12,77 1.0000 10.344 4.i91. 01.0 0.01.8 VCV i2,84 1.0000 4.966 1.725 011. 0.007 VCV 12,93 1,0000 1.798 0.557 01~' 0,079 VCV 53.08 1.,0000 21.532 7.72S 013 0,06T.'. VCp i3.i9 1.0000 1.6.806 4.984 01.4 0,006 TJCV i3,43 i.0000 i.757 0.70C.; 01.5 0.008 VCV 13.49 1..0000 2.281. 0.745 016 0.015 VCV 13.67 i.0000 4.07r; 0.728 01.7 0,007 VL'V i3.7!:i i..0000 i.94Ei 0.5>6 01.E: 0.006 VCV 13.83 i.0000 i.C.;83 0.373 019 0,017 VCV 13,99 i.0000 4.614 1..296 020 0,042 VCV 14,10 1.0000 11.590 3.358 021 0,01'7 VCV 14.24 1.0000 4,708 1.04 02;? 0,012 VCV i4.37 1.0000 3,409 0191s 023 0.020 VCV i4.49 i.0000 5.358 1,977 024 0.026 VCV 14.54 1.0000 7.226 3.115 NICOTINE 2.478 VCV 14.76 1.2000 1564, 111 248.728 025 0.065 VCV i5.03 1,0000 i7.623 3.242 026 0.020 VCV 1.5.ii i.0000 S.578 1.036 02'7 0.022 VCV i5.23 i.0000 5.990 2.587 028 0.013 VCV i5.39 i.0000 3,682 0.804 025' 0.022 VCB i5.48 1,0000 S.90i 2.349 WL.IIN[)L..7:NE:=Ia BCB iS.66 i,0000 34,149 iri.372 030 0.013 BCV i5.92 i.0000 3,627 i.07S 3.304 789,734
Page 75: nbi31d00
zrZ '~ ~ %h•s -~c Lp.~'S 1 O)h 0' O~C'£ 1 I -C0' nh '/ IllZ •r ~~ o 0 q9'/'1 ~ ~t l 'C -s £ o:O s99'<E LZ~•C ,8 Z 4'0 • 0 ~ Bb Z•,f ~ ao s~ 8 ~ fi s90 Z qh S b~ o- o 8 i ' a21 •2 ESZ •2 SS ~-4QL S -d-LL v XL ss _C$ J Z Z -G 24W z°68 ' 1& ' I f X qL$ •O -1C- Qn$• e2 ~z8 • m Loa•0 ~ Sw
Page 76: nbi31d00
s a Area Analysis F'iIe::LE:924 I MS iR4F i7t0i12i 7/22/i985 hfthc;, 45i in at 45 Chnl 0 Vial 4 0 Stnd/SMpl % 0.i25 Mthd; 45i I MS iR41T 17s2it27 7/22/1985 Naroe MG Pk RRT RRF Area Height NICOTINE 0,807 bCb 14.76 5.2000 164.803 - 73,755 ^ 005 0.045 BCB 15,04 1.0000 10.943 4.197 qUIN(lLINE;=IS FCII i5.66 1.0000 30.635- i3,5i0 r 002 0.006 BCV i5.87 1.0000 11502 0.381 0.983 207.883
Page 77: nbi31d00
Area Analysis FiIeiLE925 I W., iR4F 17i36i49 7/22/1985 Mthd; 451 Inst 45 Chnl 0 Vial # 0 Stnd/Snpl X 0.i2S Mthd: 4Si I S3 iR4F i7iS6i56 7/22/i985 Nar;e M6 Pk RRT RRF Area Height 001 0.004 BCB 12.54 1.0000 1,137 0.252 002 0.052 FsC6 12.77 1.0000 i3.598 5.680 003 0.022 BCB 13.16 i.0000 5.765 i.345 004 0.006 BCV 13,42 i.0000 1.446 011211 005 0.010 VCV i3.65 i,0000 2.625 0.679 006 0.003 VCB 0.76 i.0000 0.843 0.226 007 0,025 FsCEs i4.i0 1.0000 6.437 2.457 00C 0.002 BCB 54.55 1.0000 0.473 0.236 NICOTI:NE 2.253 BCB 14.76 1.2000 488.939 214,306 00S 0,132 BCV i5.03 1.0000 34.309 i3.678 0i0 0,005 VCV i5.i5 1.0000 1.264 0.375 0i5 0.006 VCV i5.23 1.0000 1.688 0.656 0t4 0.016 VCV 15.35 1.0000 4.283 9..318 0iry 0.043 VCB t5.48 1.0000 11.160 4.791 WUINOLINE=I3 BC$ i5.66 i.0000 32.553 13.850 014 0.009 BCV i5.92 1.0000 2.408 0.614 2.714 608.928
Page 78: nbi31d00
Area Analys.l.s Fi1ec;LE929 II S8 iR4E' i9;58;43 7/22/1985 11th0; 453, Inst 45 Chnl 0 Vial • 0 Sthd/,r,ropl % Q.i25 M•chd; 45i II 88 1R41" 20;iBs50 7/22/i9t35 Nua.e MG Pk RRT RRF Area Height OOi 0.005 HCH 12.54 1.0000 1.598 0.440 002 0.050 BCB 12.77 1.0000 14.997 5.961 003 0.019 HCb 13.16 1.0000 5.684 1.404 004 0.008 BCV 13.65 1.0000 2.362 0.649 005 0.003 VCB 13.76 1.0000 0.911 0.208 QOE. U.0i9 BCB 14.10 1.0000 5.780 2.286 007 0.008 BCV 14.33 i.0000 2.335 0.335 001, 0.009 VCV 14.S5 1.0000 2.684 0.544 NICOTINE 2.065 VCV 14.76 1.2000 513.405 225.980 009 0,02 VCB 15.03 1.0000 39.500 14.924 010 0.004 BCV 15.23 1.0000 1.343 0.674 OiS. 0.014 VCV 15.35 1.0000 4.036 1.357 012 0.038 VCB i5.48 1.0000 11.329 4.804 QUINOLINE::=IS BCV i5.66 1.0000 37.299 16.379 03.3 0.003 VCV 15.79 5.0000 0.889 0.391 0i4 0.012 VCV 15.92 1.0000 3.455 0.721 2,514 647.606
Page 79: nbi31d00
r Area Analye,is F'ile;LG`S'32 III MS iR4F 21t45tOB 7/22/i9B5 Mthd: 4Si Inst 4S Chnl 0 Vial • 0 5tnd/Srtpl % 0.i25 M h 4 1 111 MS iR4F 22 OS i4 7/22/i985 t d; 5 i ; Name MC Pk RRT RRF Area Height NICOTINE 0.800 BCB 14.76 1.2000 164.121 72.640 001 0.038 BCB iS.04 i.0000 9.35b 4.004 QUINCILINE=I3 BCB iS.hb 5.0000 30.790 13.923 002 0.005 BCV i5.87 1.0000 1.132 0.395 0.967 205.399
Page 80: nbi31d00
Area Analys.is Fi.lt:t.[:9E.9 AGAIN VI iR4F TRB 04t16t19 7/24/l.985 ilthO : 451 Int:>t 4S Chnl 0 Vial 4 0 Stnd/Snpl K 0.125 Nthd: 451 AGAIN VI SR4F TRB 04t36:25 7/24/i9t35 Nar•.e MG Pk RRT RRF Area Height N1:COTIN[: 0.021 8C8 14.78 1.2000 3.993 1.219 QUINCIIINE'=IS BCTi 15.66 1.0000 20.702 12.997 0.146 32.775
Page 81: nbi31d00
Area Analys~is Fi.1c:IL_l:5'3i II TRB iR4F 2i109139 7/22/1985 Mthc;; 45]. :[rist 45 Chnl 0 Vial 4 0.citnd/Snpl Z 0.125 M1'hd I 455. II TRF3 1R4F 21129146 7/22/19E3S Nnr•,e MG Pk RRT RRF Area Height NICOTINE 0.035 BCH i4,77 1.2000 r,946 2.10S QUIN4I..INE'=18 BC£t 15.66 i.0000 25.566 ii,i23 0.160 31.51?
Page 82: nbi31d00
Area Analys.i.s F'ile;l..'L'973 V iR3 TRA 06;38;04 7/24/1985 ?ith<J; 451 lrist 45 Chr11 0 Vial * 0 Stnd/Snpl X 0.i25 Mthd; 45f. V iR3 TRA 06;58;12 7/24/i985 Nane 0Oi MG 0.014 Pk VCV RRT 12.16 RRF 1.0000 Area 3.068 Height 0.753 00~:' 0.007 VCV 12.26 1.0000 1.449 0.563 003 0.007 VCV 12.34 1.0000 1.534 0.354 00A, (1.012 VCV 12.42 1.0000 2.693 1.098 005 0.039 VCV i2.Ci3 1.0000 8.495 2.604 00r:, 0.016 VCV 12.59 5.0000 3.394 1.204 007 0.029 VCV 12.73 i..0000 6.261 l..657 00t; 0.037 VCV 12.78 1.0000 7.887 3.139 007 0.016 VCV 12.84 1.0000 3.474 9..203 09.0 0.005 VCV i2.93 1.0000 1.125 0.338 Oif. 0.077 VCV 13.08 1.0000 16.618 G'i.988 01 C' 0.040 VCB 13.14 1.0000 8.634 2.547 013 0.013 PCP 13.43 1.0000 2.701 0.453 0in 0.012 11CV 1.3.99 1.0000 2.609 0.858 015 0.032 VCV 14.10 1.0000 7.008 1.725 01 6 0.009 VCV 14.24 i.0000 1.886 0.756 017 0.007 VCV 14.37 1.0000 1.440 0.492 0 1 Ec 0.013 VCV 14.50 1.0000 2.818 1.00U 0 S. 9 0.021 VCV 14.54 i.0000 4.456 f..924 0 %'. 0 0.002 VCV 14.63 1.0000 0.480 0.233 NIC(]TINE: 3.,749 VCD 14.76 1.2000 314.826 140.946 021 0.040 1+CB 15.04 1l0000 8.709 2.133 0 PP. 0.017 BCV i5.23 1.0000 3.644 1,,717 0 2;. 0,007 VCV 15.38 1.0000 i.53f. 0.374 0'2 4 0.0f.1. VC}:c i5.49 1.0000 2.326 1..002 6l1.)INGLINE >• IS HCT) 15.66 1.0000 26.999 ii..844 02S 0.012 F.ICV 15.92 i.0000 2.578 0.792 2.369 448,653
Page 83: nbi31d00
Area Annlysis F'ile;L.F:935 III TRE iR4F" 23e3is31 7/22/i9F35 t4thci; 451 Inst 45 Chnl 0 Vial 4k 0 Stnd/Smpl % 0.i25 Mthd: 45i III TRB iR41' 2315ii37 7/22/i9EF5 Narse MG Pk RRT RRF Area Height NICOTINE 0.028 BCH 14,77 1,2000 5.i52 2.263 Ql.1INDl_ING..-IW BCB 15.bb 1.0000 27,545 12.321 001 0.006 BCV iS.87 1.0000 1.386 0.377 0,i59 34,083
Page 84: nbi31d00
.4 0 Area Arralyai>a f`i7.~: ;L.E967 AGAIN VI iR4F wE 03:05t25 7/24/i985 Mthc; : 451 inst 45 Chnl 0 Vial i4 0 Stnd/Sap2 % 0,125 Mthd; 45i AGAIN VI iR41T S3 03125c32 7/24/1985 Name 11G Pk RRT RRF Area Height 001 0.0ii VCB 12.02 1.0000 3.570 0.416 00c^ 0.004 BCV 12.34 1.0000 1.218 0.3i6 003 0.0i6 VCV 12.49 i,0000 5.150 0.592 004 0,060 VCD iti,77 1.0000 19,0713 6.605 005 0.009 BCV 13.10 1.0000 3.010 0.955 006 0.027 VCEr 13,15 1.0000 8.498 2.956 007 0.008 BCV 13.67 1,0000 2,456 0.681 OOE: 0.004 VCB 13.76 i.0000 1.401 0.656 009 0.023 FiC2# 14.10 i.0000 7.276 3.282 05.0 0.012 k'rCV 14.50 i.0000 3.765 0.770 OS.i 0,00B VCV 14.55 1.0000 2.653 0.782 0f.i' 0.005 VCV 14.63 1.0000 1.569 0,516 NIC01INE 2,772 VCV 14.76 1.2000 732.972 321.671 013 0.016 VCV 14.97 1.0000 5,17B 1.342 014 0.114 VCV 15.03 1.0000 36,285 14.770 05.5 0.011 VCV i5.i4 1.0000 3.419 0.756 016 0.012 VCV i5.23 i.0000 3,885 i.i43 017 0.028 VCV 15.35 1.0000 8.780 i.730 0i8 0.051 VCV 15.48 1.0000 16,325 6.004 QUINOL.INE--IS VCV 15.66 i.0000 39,659 14.127 0l.7 0.020 VCV 15.9i i.0000 6.424 1.287 3.338 912.572
Page 85: nbi31d00
I 0 .0 Areu Analyx.is Fi:Ie ;LE:9bb AGAIN VI SR4F MS 02;29r58 7/24/i985 tlthu; 451 Inst 45 Chnl 0 Vial # 0 Stnd/Sropl Y. 0.125 Mthdr 45f. AGAIN VI iR4F MS 02r50105 7/24/19E15 NarsF MG Pk RRT RRF Area Height NICOTINE 0.811 BCB 14.71a 1.2000 149,483 b&.f.32 OOf 0.039 BCB 15.04 1.0000 8.712 3.813 WIJINl7l.]:NF-I3 BCB 15,66 1.0000 27.660 12.253 0.975 i85.855 I
Page 86: nbi31d00
Area Analys.is F.i1etLE930 11 TRA iR4F 20t341i2 7/22/i985 Hthc; ; 45i Inst 45 Chnl 0 Vial # 0 Stnd/Srop1 X 0.i25 Mthd; 45i II TRA iR4r 20i54119 7/22/1985 Nrarse i1G Pk RRT RRF Area Height 001 0,016 BCV 12,17 i,0000 3.476 0.941 D0:'.' 0.000 VCV 12,25 1.0000 1.641 0.535 003 0.021 VCV 12.42 1.0000 4.475 1.267 004 0.060 VCV 12.53 1,0000 12.913 3.121 005 0.026 VCV 12,72 i.0000 5.55i 1.476 006 0.024 VCV 12,78 i.0000 5,239 2.034 007 0.019 VCV 12.84 i.0000 3.960 1.398 00fl 0.007 VCV 12.94 i.0000 1.404 0,429 009 0.083 VCV 13.08 1.0000 17,862 6.604 0i0 0.051 VCB 010 1.0000 10.826 3.416 01i 0.0i0 BCV 13.44 1.0000 2.078 0.497 012 0.005 VCB 13.61 1.0000 1.069 0.212 013 0.012 BCV 13.99 1.0000 2.662 0.974 03.~ 0.027 VCV 14.1i 1,0000 5.870 1.714 0f.5 0.019 VCV 14.24 1.0000 3.974 0.854 SiL 0.007 VCV 14.36 1.0000 1.604 0.368 03.7 0,016 VCV 14.49 1.0000 3.393 l..309 0S.F 0,021 VCB 14.54 1.0000 4,438 2,074 NICOTINE 2.071 BCB 14.76 1.2000 369.189 167.324 019 0.045 BCV 15.03 1.0000 9.632 2.003 020 0,01f. VCV 15.i2 1.0000 2,278 0.551 021 0.024 VCV 15.23 i.0000 5.i76 2.238 022 0,008 VCV iS.38 1.0000 1.624 0.416 023 0.009 VCB 15.49 i.0000 1.860 0.761 Gtl1INDL.INE-IS BCB i5.66 1.0000 26.741 11.964 024 0.0i5 BCV 15,90 1.0000 3.110 0.623 2,739 512.046
Page 87: nbi31d00
Areu Analyt.is 1='iIe:LE926 I TRA iR4F 18:12:1B 7/22/i985 Mthcl: 455. Inst 45 Chnl 0 Vial # 0 Etnd/5np1 Z 0.525 Mthd; 4S1 I TRA iR41"' 18:32:26 7/22/i985 Nr,iN. 2 MG Pk RRT RRF Area Height 001 0.017 VCV 12.16 1.0000 3.950 i.015 002 0.011 VCV 12.25 1.0000 2.495 0.857 003 0.011 VCV 12.36 1,0000 2.546 0.650 004 0.017 VCV 12.42 1.0000 3.814 1.430 005 0.068 VCV 12,53 1.0000 15.694 3.634 0 06 0.028 VCV 12.73 1.0000 6.328 1.798 007 0.044 VCV 12.77 1,0000 10.060 4.110 00f: 0.019 VCV 12.84 1.0000 4.420 1.684 009 0.006 VCV 12.93 1.0000 1.402 0.4i9 010 0, 085 VCV 13.08 1.0000 19.530 7.329 Oii 0.069 VCB 13,19 1,0000 15.84i 4.384 0i2 0.007 BCV 13.43 1.0000 1.664 0.586 013 0.009 VCV 13.49 1.0000 2.037 0,674 014 0.016 VCV 13,64 1.0000 3,630 0.868 0l.5 0.011 VCB 13.75 1.0000 2.643 0.435 01.f.. 0.012 BCV 13.99 1.0000 2.866 1.054 017 0.045 VCV 14.10 1.0000 10.250 2.773 0S.£i 0.010 VCV i4.c^.4 1.0000 2,365 0.935 05.9 0.009 VCV 14.38 1.0000 2.072 0.559 020 0.015 VCV 14.49 1.0000 3.368 1.356 021 0.021 VCB 14.54 1.0000 4.793 2.281 NICOTINE 3,180 BCB 14.76 1.2000 609.363 269.335 022 0.070 BCV 15.04 1.0000 16.144 3.765 023 0,014 VCV 15,13 1.0000 3.259 0.784 024 0.026 VCV 15.23 1.0000 6.009 2.778 02~; 0.012 VCV 15.39 i.0000 2.727 0.665 026 0.030 VCB 15.48 1.0000 6.893 2.958 QU:f NLIL.INE-Iu BCV i5,66 1.0000 28.744 12.718 027 0.022 VCV 15.92 1.0000 5.143 1.114 4.009 800.049
Page 88: nbi31d00
01 Area Analyti•is Fiae;L.E933 Mthd; 45i Mthd 45i III SS iR4F Inst 45 Chnl 0 III 85 iR4F Vial t 22;20s36 0£tnd/£iropl % 22 40 43 7/22/i9BS 0.i25 7/22/198S ; Naroe MG Pk RRT RRF s t Area Height 00i. 0.007 BC13 i2.53 1.0000 2.047 0,460 () 0'i' 0.053 BCB 12.77 1.0000 16.471 6.319 003 0.026 llCb 13.i6 1.0000 8.123 2.237 004 0.004 PCB 13.44 1.0000 1.124 0.296 0D5 0.0i0 BCV 0.65 1.0000 3.159 0.869 0Db 0.008 VCB 13.76 1.0000 2.340 0.441 007 0.022 FsCH 14.10 1.0000 6.700 2.589 0() el 0.002 BCit 14.54 1.0000 0.509 0.237 NICOTINE 2.298 BCB 14.76 1.2000 591,432 262.053 005' 0.i20 BCV i5.03 i.0000 37.0iS 14.948 010 0.005 VCV 15.14 1.0000 1.392 0.366 0 11 0.006 VCV iS.23 1.0000 1.731 0.638 01.2 0.017 VCV i5.3S i.0000 5.370 1.604 01.3 0.061 VCV iS.48 i.0000 i8.86i 7.354 WUINC)1..7NE:=a3 VCV 15.66 1.0000 38.598 i4i.645 014 0.008 VCV iS.78 1.0000 2.555 0.712 Oi.5 0.01.7 VCV i5.9i 1.0000 5.i08 01931 2.788 742.538
Page 89: nbi31d00
, 2 _J~~_..----------~~..~_.~~r~-- -------- ~ -~ ~ i?---.. -SS_ (A 7ir79 rs4.Ri5J pqlg ~ JpaF ms --~~ J0. RJ6Z 50. 90a n5a _, r~4J% s ~- -_.~~~ ~LAS _ --- -------~----~ , n ! !z LP4F AS f UF 55 - - , . ~ ~ 2StF 'T"~A _41 Jb ~1,a,n , 7 l2A F TrAnB 4 10 ~~ !R1 ---=__P.~_1e 53 ccC 72oQ zol IO6a ~1 lQ~ Ms MS - 5b. 4(oD7 .51 N%W05jg _ OqI I 'V'f, fk)! SS es;u.RL- 'I I 21 Trai3R_ ~ II J I l a~, J a:g ~A! Trc~ g- 2--- 11 a~J ~I~oi~
Page 90: nbi31d00
Areu Ar:alyu.is 1-i].r:;L.L":5'68 AGA1N VI iR4F TRA 03:40:52 7/24/i985 11thd; 45i ln>t 45 Chnl 0 Vial # 0 Stnd/8Mp1 % 0,i25 Mthd: 451 AGAIN VI iR4(' TRA 04:0it0i 7/24/i985 Naroe MG Pk RRT RRF Area Height 00i 0,010 DCV 12,16 1.0000 2.405 0.585 00P 0.005 VCV i2.25 1.0000 1,141 0.413 003 0.016 VCV 12.42 1.0000 3.672 0.936 004 0.046 VCV i2.S3 1.0000 10.869 2.3i5 005 0.024 VCV 12.72 1,0000 5.550 i.570 006 0.025 VCV 12.78 i.0000 5.843 2.257 007 0.017 VCV 12.84 110000 4.095 1.411 00E1 0.009 VCV 52.94 i.0000 2.i68 0.472 009 0.070 VCV 13.08 i.0000 16.405 5.682 09.0 0.038 VCV 13.19 110000 8.879 2.565 Oil 0.027 VCB 13.48 1.0000 6,282 0.604 0ic' 0.010 BCV 13,99 1.0000 2.3i5 0,700 013 0.021 VCV i4,ii 1.0000 4.960 i.488 014 0.014 VCV 5.4,24 1.0000 3.i9B 0.830 0i5 0.006 VCV 14,36 f„0000 i.510 0.387 016 0.0i5 VCV 14.49 1.0000 3,523 1.277 01.7 0.022 VCB 14.54 i.0000 5,i35 1.849 NICOTINE 1.462 BCV i4.76 1.2000 285.330 129.208 Oi8 0.038 VCS i5.03 1.0000 8.934 i.655 015' 0.0i5 BCB i5.23 1.0000 3.427 1.642 020 0.005 FICV 15,49 1,0000 1,189 0.5i4 QU7NOLTNE==15 VCB i5.66 1.0000 29,279 i2.431 021 0,0i0 E{CV i5.90 1.0000 2.427 0.570 2,030 418.537
Page 91: nbi31d00
I iZzf -F - -- =a3.-&- : _ ~1S ~o A~c~3 L r~G~i 44 l46tA0 Lo4 $R7 -- -- -- -- - 2 1~ufFs puFPs ~ . ,L)OLN-._I CA-_.- ~~/L 1 A {a~~ . o50~, T~iR~ m 15L7 " " s5 r /1 7i y ~r1C aa-" -1AJ -a ra"f;:- - S" ---_~ 55 ---- e~ ~ ~~ - cz-.__.ro - -__ --.~.---~ ; 9 ' OD
Page 92: nbi31d00
14 `7- 77. ~' ~snn c~~v ly kz f ~J ~KL ~} D.. l'Mr _--- T-I-KA-r" _ i ~<,, ;1 ~~~ ~ ~ 11 ~u(1~ .. - .. ,_.... . ...l51._ .tC ~3_ - ~'~~UV~---------------- a~ f~~~= ~ - _ ~ _- _ ___---- - v~ t F Y1 ~ IOl ~' s' ~ ~ ~ -. -_ - - _ _ ----- - _. --__ _ --- ----_ --- ---- ---- - -- ------ l C _ L_Q F Irt~ f~_ tn --- w ; }(, ~~~x{45 ~ _ ---- W S =i _ } U c LO {I 6`I ` '''5 S 5U_ ----- - 1la I ~`~F ~r'~r~_ _ _ -_- I vf I,< eLri~u{ ~, - ~ - 1D `~~~~_ - - _ __ - -- ------- - ---- -------- ------ -- --- _- 5 I ~; p,,~~:Y------ -----------------__ ~ U ' - - _ --- ---
Page 93: nbi31d00
Area Analye.is Fi.Ie;I.E:S'34 mthd t 4a1 III TRA iR4F Inst 45 Chnl 0 Va.a1 4 22:56:04 7/22/1985 0 Stnd/BMpl % 0.125 MrP:d: 451 Namr> III TRA iR4f' Mr Pk RRT RRF 23:16:12 Area 7/22/i985 Height 001 0.0i5 VCV 12.16 1.0000 4.086 1.228 002 0,009 VCV 12.25 1.0000 2.509 1,053 003 0.014 VCV 12.34 110000 3.723 i..084 004 0.0i5 VCV 12.42 1.0000 3.991 1.714 005 0.052 VCV 12.53 1.,0000 13.95i6 4.196 00f, 0,021 VCV 12.59 1.0000 5.602 i.923 00'7 0,031 VCV 12.72 1.0000 8.349 2.604 O0E:f 0,057 VCV 12.77 1.0000 15.449 6.338 009 0.019 VCV 12.84 1.0000 5.005 3..926 0s.0 0.007 VCV 12.94 1.0000 1.803 0.687 01.1 0.094 VCV i3.08 1,0000 25.252 9.748 01:.'. 0.046 VCV 13,15 1.0000 12.279 5.418 0i.3 0.042 VCV i3.i9 1.0000 11.255 S.S04 014 0.006 VCV i3.35 1.0000 i.6i5 0,518 Ois 0.012 VCV 13.43 1.0000 3.i35 1.051 016 0.012 VCV 13.48 1.0000 3.293 1.041 017 0.0i8 VCV i3.65 1.0000 4.983 1.143 0 10 0.007 VCB 13.75 1.0000 1.925 0.975 019 0,014 BCV i3,99 1.0000 3.770 i..i83 020 0.050 VCV 14.10 1.0000 13.473 4.226 0~.'.i 0.0i9 VCV 14.24 i.0000 5.156 1.375 022 0.017 VCV 14.37 1.0000 4.620 0.9i0 023 0.022 VCV 14.49 i.0000 5,869 2.181 024 0.030 VCV 14.54 i.0000 8.058 3.S14 0?5 0.008 VCV 14.62 1.0000 2.110 0.569 NICOTINE 4.304 VCV 14.77 1.2000 967.018 425.074 026 0.102 VCV 15.03 1.0000 27.624 6.776 027 0,022 VCV i.S,12 1.0000 5.963 1.293 028 0.034 VCV 15,22 1.0000 9.062 4.069 029 0,020 VCV 15.34 1.0000 5.466 0.979 030 0.046 VCB 15,48 1.0000 12.518 5.355 QUINOLINE"=Iti3 BCV 15.66 1.0000 33,704 i5.i34 031 0.002 VCV 15.78 1.0000 0.585 0.237 0:.3u' 0.023 VCV SS,91 1.0000 6.277 1.416 S.314 1239.487
Page 94: nbi31d00
-t Area hrwlyta m 1"i.].c:;LE2Si 1 P207 bi;; 17s09107 7/25/i9B5 Mthd; 4S1 InSt 45 Chnl 0 Vial # 0 Stnd/8rop1 X 0.i25 Mthci; 451 I P207 M.i M29ti4 7/25/1985 Nr,me MG Pk RRT RRF Area Heiqht 00i 0.005 BCB 12.74 1.0000 1.278 0.306 00? 0,004 BCB 14.ii i.0000 1.047 0.445 NICOTINE i.i23 BCB 14.76 1.2000 241.Bi3 107.285 003 0.056 BCB i5.03 1.0000 14.557 6.374 QUINLtt.INEv=I8 BCB i5.66 1.0000 32.310 14.ii7 5.313 291.006
Page 95: nbi31d00
T59'0 005'0 06210 15910 0000' T 99' 5T HaH taz-ANFIutrT.nm 000$'T LL'bT TINIl(]OIN 140TaH oa•jv .lMi! 1bN Hd JW at4nry S06T/5?/L SbI £519T `Id3 U18 T5b 'pilaW 005' 0 % tdWS/pu15 0 # LpTA 0Vi'd3 ab "''I TSb : nya.y! 5i35T/5"4'lL 6E12£19T '1VO (I15 0 au:71+ aTT.:1 'iTs/StAll6i fSa.1l)
Page 96: nbi31d00
r; Area Analyt.is f`.iI«: :LE:252 I P207 SS 17344;35 7/25/1985 Nthd: 451 Inst 45 Chnl 0 Vial * 0 Stnd/Srtpl X 0.125 Nthd: 451 I P207 S3 l8:04:42 7/25/1985 Name MG Pk RRT RRF Area Height 001 0.006 VCB 12.03 1.0000 2.330 0.408 002 0.004 BCV 12.36 1.0000 1.609 0.405 003 0.010 VCV 12.53 i.0000 3.566 0.671 004, 0.053 VCB 12.77 1.0000 19.242 7.769 005 0.030 BCV 13.15 1.0000 10.780 2,817 006 0.014 VCV 13.68 5.0000 5.028 0.911 007 0.003 VCB 13.76 1.0000 1.200 0.425 00E: 0.021 BCB 14.10 1.0000 7.591 3.185 009 0.004 DCV 14.38 1.0000 1.297 0.286 0i0 0.007 VCV 14.55 1.0000 2.444 0.508 NICOTINE 1.991 VCB 14.76 1.2000 597.630 261.460 0ii 0.105 BCV l5.03 1.0000 37.968 i5.252 012 0.003 VCV i5.i4 1.0000 1.247 0.301 0i' 0.006 VCV 15.23 1.0000 2.167 0.878 014 0.019 VCV 15.35 1.0000 6.9i3 1.829 0i5 0.068 VCV i5.47 1.0000 24.494 10.071 4UINOLINE-IIS; VCV 15.66 1.0000 45.034 .17.567 OiC. 0.014 VCV 15.92 1.0000 4.934 1.13E1 2.484 775.476
Page 97: nbi31d00
Areu Anulys•is Filc-i1.E:2S4 I P207 TRP i8I55133 7/25/i9BS MthW : 451 Inst 45 Chnl 0 Vinl # 0 Etnd/8Mp1 X 0,i25 Mthd; 451 I P207 TRB 19ti5t39 7/25/19D5 Nnme MG Pk RRT RRF Ar•eo Height NICOTINE 0.037 8CH i4,77 1.2000 6.662 2.902 QUINOLIPlE=IS BC$ 15,66 1.0000 27,117 12,353 0,162 33,779
Page 98: nbi31d00
TDJD oZrb z°-7 -:;) - ~Z41=3w s4-s,n f/J /,~S 5 S "D2 `4- "ryL r3 Td4r,-~ w, c S'S' 2•76S a.oy7 y 6 B ~ 1, Z°`f 1•9 S- 2-79Z o-039 ~ S I _ ~ I• i 9 a. 3~a ~ aas d~ ;?llS a LO& O Oa9 ---- Ln r W m __. OD ( a,.. a .. Q-e....
Page 99: nbi31d00
Areu AnalyLia, 1-i1e oLC.25S II P207 PiS i9t3i101 7/2S/i9B5 Mthc;; 45i lnst 45 Chnl 0 Vial * 0 Stnd/Saspl % 0.i2S Nthd; 4Si II P207 MS i9t5i:08 7/25/i9BS Nar,e MG Pk RRT RRF Area Height 00i 0.012 BCB 12.79 1.0000 2,82S 0.336 002 0.002 BCEi 13,68 1,0000 0.521 0.206 003 0.004 I3CH 14,ii 1.0000 1.080 0.469 NICOTINE 1.174 BCB 14.76 1.2000 235,B92 105.i09 004 0.060 BCB 15.03 1.0000 14.411 (a.387 qUINQLINFwIS HCP i5.66 1,0000 30.i3?.. 13.430 1.377 284.862
Page 100: nbi31d00
Area Ariulyb.ib F i I r• ; L E260 Hthu; 451 171 P207 SS 7nst 45 Chnl 0 Viul * 22)28123 7/25/1985 0 Stnd/Srop1 X 0.i2S M thd; 451 III P207 55 22048i30 7/25/i985 Nurle KG Pk RRT RRF Area Height 001 0.009 VCB 12.03 1.0000 3.332 0.417 002 0.003 BCV 12.35 1.0000 1.215 0.376 003 0.008 VCt+ 52.50 i.0000 2.866 0.480 004 0.049 HCb 12.77 1.0000 17.607 6.981 005 0.007 BCV 13.11 1.0000 2.543 0.880 006 0.024 VCV 13.i5 i.0000 8.606 2.940 007 0.018 VCV 13.68 1.0000 6.344 0.963 OOEt 0.004 VCB 13.76 i.0000 i.550 0.457 009 0.019 SCH 14.10 1.0000 6.842 2.933 010 0.004 BCV 14.38 i.0000 1.5i3 0.357 01i 0.009 VCV 14.55 1.0000 3.058 0.579 NICOTINE 1.975 VCV 14.76 i.2000 589.568 259.490 012 0.013 VCV 14.98 1..0000 4.611 l..252 0J.3 0.iQ6 VCV i5.03 f..0000 37.882 15.741 014 0.008 VCV 15.14 1.0000 2.996 0.686 0 S. S, 0.009 VCV i5.23 i.0000 3.109 0.977 016 0.023 VCV i5.35 1.0000 8.402 1.733 0f.7 0.069 VCV i5.48 1.0000 24.748 9.637 WUINOL.]:NE==IB VCV i5.66 1.0000 44.788 15.757 010 0.018 VCV 15.92 1.0000 6.312 1.291 2. i00 777.894
Page 101: nbi31d00
Ar•ea Analysit. Fi1e-A.EM I Mthd; 451 P207 TRA Imat 45 Chnl 0 Vial • M2003 7/25/1985 0 8tnd/£ropl X 0.125 Nthd: 451 :C Nur,e P207 TRA MG Pk RRT RRF i8t40:1i Area 7/25/1985 Height 001 0.006 VCV 12.03 1.0000 1.749 0,467 00? 0.018 VCV 12.i6 i.0000 5.065 1.224 003 0.008 VCV 12.25 1.0000 2,316 0.761 004 0.014 VCV 12.33 1.0000 3.970 i.i42 005 0,012 VCV 12.42 1.0000 3.451 1.396 006 0.046 VCV 12.53 1.0000 13.354 3.882 007 0.016 VCV 12.59 1.0000 4,680 1.582 008 0.028 VCV 12.72 1.0000 7,955 2.285 009 0,044 VCV 12.77 1.0000 12.750 4.993 0i0 0.017 VCV 12.84 1.0000 4.927 1.872 01i 0.006 VCV 12.94 1,0000 1.871 0.552 012 0.083 VCV 13.08 1.0000 23.832 B.548 03.3 0.071 VCV l3.19 1.0000 20.491 5.394 014 0.0i6 VCV 13.43 1.0000 4.653 1.018 0i5 0.013 VCV 13.48 1.0000 3.855 0.053 OiE. 0.010 VCV 13,60 1.0000 5.069 0.839 017 0.010 VCV 13,75 1.0000 2,744 0.854 0113 0.007 VCV 13.84 1.0000 2.040 0.460 019 0.016 VCV 13,99 1.0000 4.681 1.448 020 0.039 VCV 14.10 1.0000 11.283 3.521 021 0.015 VCV 14,24 1.0000 4.421 f..183 022 0.009 VCV 14.37 1.0000 2,730 0.799 021 0,013 VCV 14.49 1.0000 3.884 1.580 024 0.019 VCB 14.54 1.0000 5.542 2.740 N7:CClTINC 2.519 BCV 14.76 1.2000 604,422 268.679 0G!7, 0.070 VCV 15.03 i,0000 20,045 4,409 026 0.017 VCV 15.11 1.0000 5.000 0.984 027 0.025 VCV 15.22 1.0000 7.160 2.974 028 0.017 VCV 15.39 1.0000 5.024 0.938 029 0.039 VCV 15.48 1.0000 11.250 4.515 QUINOLINE:==IFS VCV 15.66 1.0000 35.985 14.372 030 0,019 VCV i5.91 i.0000 5.48i 1.344 3.378 85i.684
Page 102: nbi31d00
bTS'S82 80b'i ST2'£T 59S'62 0000'i 99'ST 03a 3T='3WIlOMLf1C] 829'9 4'u2'ST 0000'T £0'ST 1338 b90'0 voo 00T'50T T9Z'L£2 0002'T 9L'bT H3S b02'T :7WI10:]IN S2b'0 82T'T 0000'T TT'bT 039 500'0 £oo 502'0 500'T 0000'T 09'£T H30 b00'0 aoo 00£'0 Lu£'T 0000'T hL'ET d3H 900'0 TOO ly®iaH uaitl A19s lbi! U 8W asdory S86T/52/L T0I£TI 22 SW L02d III T5b : pi.l.tW 52i'0 X tdWB/pui8 0 # inin 0 LU43 Sb Isul: T':a6 ip4.4W S86T/52/L .''oSt2SIi2 84d L02d III 65731 1?L TJ 3T•aAinuij naJp _0 1
Page 103: nbi31d00
L Area Analyti.is 1`i1(r:LF:2f)2 III P207 TRB 23t39ti9 7/25/i985 Mthd; 451 Ins.t 45 Chnl 0 Vial Ik 0 Stnd/Sropl X 0.i25 Mthds 451 III P207 TRB 23s59125 7/25/i985 Nuarr: MG Pk RRT RRF Area Height NICOTINE 0.039 BCB i4.7b 1.2000 7.151 3.04 QUINOLINE=IS BCB 15.b6 1.0000 27.331 i2.i8b 0,164 34.482
Page 104: nbi31d00
t Area Arwlymis filL.C2r,E II P207 TR£c 2i1i7s26 7/25/i905 Mthu; 45i Inst 4S Chni 0 Via1 • 0 Etnd/Sropl x 0.i25 Mthd: 45i II P207 TRF1 21t37i33 7/25/i985 Nume MG Pk RRT RRF Area Heipht• NICOTINE 0.043 BCDt 14.77 5.2000 7.999 3.i67 QU1NOLl:NE`=IS BCfi IS.66 1.0000 27.771 12.490 0.168 35.771
Page 105: nbi31d00
+w ' ~ lls)~C> A 5 S N'tc~}ine 7- 2~~ 8~ c~mF~LP 1 D ~ i~ u, I ~a,d wt befn~ ~ r :t~fd SS -- ~~ faRi3 Cn~~~ '` ll$~I' - Z' YDbD7,oZi2 Ms - --- ~ R~f e + T -- 3 10 m5 ........... -- ~ - -2 - Ln ~ OD Q ~ Ln W - -P~~-- t - ~-~ ld4lLo~`7 ~~l ?$c57 /lie~ L"~U--'DL~o2c~t ?' ~~------------ L._ r~ 6 ID - ~ -- ~
Page 106: nbi31d00
Areu Fmuly!-.iz C"i1l.C:257 II P207 TRA 20;41t57 7/2r:,/1985 t4•tly4; ; 4s1 Iw xt 45 Chnl 0 Vial # 0 5tnd/Enp1 X 0.12S ii-thti; 451. II P207 TRA 21102;06 7/25/i98S Narse t1C C'k RRT RRF Area Height G07 0,009 VCV 12,03 1.0000 2.307 0.607 0011' 0.021. VCV i2.i6 i,0000 5.315 i,ii0 003 0.010 VCV 12,25 i,0000 2.444 0.924 004 0.015 VCV 12.33 1.0000 3.767 0.935 0D5 0.012 VCV 12.42 1,0000 3.174 i.,355 006 0,048 VCV 12.53 1.0000 12.i93 3.570 007 0.018 VCV 12.59 1.0000 4.700 1..49'7 DOt: 0.032 VCV 12.73 1.0000 8,146 2,168 009 0.048 VCV 12.77 5.0000 12.148 4,970 0l0 0.019 VCV 12.84 1.0000 4.882 1.774 0ii 0.007 VCV 12.94 1.0000 1.853 0.639 0i2 0,086 VCV 13,08 i,0000 22,103 7.698 0i;i 0.080 VCV 53.18 1.0000 20.552 5.707 01.4 0,017 VCV 13.44 1.0000 4,221 0.933 0i5 0.015 VCV 13.48 1.0000 3.782 0.935 Dif. 0.0i0 VCV 13.61 1.0000 2.512 0,704 017 0.012 VCV 0.68 1,0000 3.086 0.965 01.E~ 0.010 VCV i3.75 1.0000 2.536 0,779 019 0.022 VCV 13.99 1,0000 S.670 5..089 020 0.044 VCV 14.50 1.0000 11.229 3,525 021 0.016 VCV 14,24 1.0000 4.178 l..148 022 0.009 VCV 14.37 1.0000 2.252 0,571 023 0.0i5 VCV 14.49 1.0000 3.720 1.553 024 0.022 VCB 14,54 1.0000 5,549 2,627 NICOTINE 2.769 BCV 14.76 1.2000 590.i58 263.163 04'r. 0.079 VCV i5.03 1.0000 20.204 4.544 026 0.019 VCV 15.ii 110000 4.848 0.951 02'7 0.024 VCV i5.23 1.0000 6.062 2,590 028 0.017 VCV i5.39 1.0000 4.259 0.794 029 0.044 VCV 15, 48 1.0000 ii, i'.i5 4.65i WUINQL_INC-]:S VCB 15,66 1.0000 31.967 13.384 030 0.014 I{CV i5.92 1.0000 3.662. 1.119 3.686 824.636
Page 107: nbi31d00
Area Ariulysii:. f°i1r;LC26G IV P207 TRB M0it05 7/26/i9B5 tlthcz, 45i Inst 4S Chnl 0 Via1 i 0 Etnd/Enpl X 0.i25 Mthd; 451 IV P207 TRB 02r2itii 7/26/i9Ha Nar.e MG Pk RRT RRF Area Height NICOTINE 0.018 HCB 14.77 1.2000 4.173 i.695 OUINOLINE=IS BCB 15.66 1.0000 33.848 i5.423 0.143 38.020
Page 108: nbi31d00
- - - ~ ~ m - ~ ~ ~ -- -- ZfI-- b , -~-r- ~ ------__ ----_ _ ~ ~2 - --- -- Q --~ ---~- - ---- -------- - -~ ~ - --1- g-~ -- -__ _ _ ~unoJ ;J -~- S~______ --- - -- swt~~-- 6 L,ooT~s 8Co 1~ -_-~, - ~-- ~------- _ _~ ------ _---- 8;~ y ----- ss - --~~~-- ' ; _ - ~y-----~------ --- _ _ ~ ----- --- .~~.. 6 S~_~_ . --- -------- - -- ttL~~~0C ___ ._ 1c1 NYlL 1
Page 109: nbi31d00
•J Area Analyt•ism F'ile;C.E263 IV P207 1•SS 00ti4r44 7/26/i985 Mthrr, 451 Inrnt 45 Chnl 0 Vial # 0 Etnd/SMpI % 0.i25 Mthd: 451 IV P207 MS 00i34t5i 7/26/1985 Nar.e MG Pk RRT RRF Area Height 001 0.010 6C8 12.74 1.0000 2.764 0.405 002 0.003 BCB 13,68 1.0000 0.858 0.285 003 0.005 FiCN 14.11 1,0000 1.516 0.577 NICOTINE i,192 BCB 14.76 1,2000 275.536 124.788 004 0.062 BCB i5.03 1,0000 17.066 7.610 QUIPlOLINF'mI8 BCB i5.66 1.0000 34,661 i5.283 1.398 332.401
Page 110: nbi31d00
l Areu Analyh•ia Fi14:o1F4S6 11 P207 SS 20;06128 7/25/1985 T1thc; ; 451 Iw~t 45 L'hn1 0 Vial # 0 Etnd/Eropl X 0.12S t7thd; 451 II P207 83 20sM3S 7/25/i985 Naase MG Pk RRT RRF Area Height 001 0.008 VCB 12.04 1.0000 2,343 0.403 002 0,003 BCB 12.50 1.0000 0.979 0.230 003 0.049 BCB 12.77 1.0000 15.268 6.404 004 0.024 BCV 13.i6 1.0000 7.413 1.782 005 0.016 VCV 13.68 1.0000 4.971 0.901 006 0.004 VCB 13.76 1.0000 1.220 0.424 007 0.021 BCB 14.10 1.0000 6.562 2.659 00E 0.010 BCV 14.5S i.0000 3,244 0.434 NICOTINE i.865 VCB i4.76 1.2000 481.031 213.927 009 0.419 BCV i5.03 1.0000 36.968 15,093 010 0.002 VCV i5.14 1.0000 0.744 0.222 015. 0.002 VCV i5.23 1.0000 0.618 0,253 05.2 0,016 VCV 15.35 1.0000 4.798 1.406 013 0.056 VCV i5.47 1.0000 17,441 7.530 QU]:NOLINE=I5 VCV 15,66 1.0000 38.688 15.246 014 0.010 VCV 15.92 l,0000 3.036 0.760 21331 625 . 325
Page 111: nbi31d00
i Area Anulyt•is f"ilc:LE:26t III P207 TRA 23t03t50 7/25/i985 Ntho': 4c;i Irist 45 Chnl 0 Vial 4 0 Stnd/Sropl X 0.125 Mthdt 451 111 P207 TR A M23I59 7/25/1985 Nume MG Pk RRT RRF Area Height 001 0.008 VCV 12.04 1.0000 1.850 0,580 002 0.021 VCV 12.16 1.0000 4.960 1.107 003 0.008 VCV 12.26 1.0000 1.936 0,726 004 0.014 VCV 12.34 i.0000 3,315 0.967 005 0.013 VCV 12.42 1.0000 3.049 1.222 00E. O.Of;1 VCV 12,53 1,0000 11.880 3.488 007 0.017 VCV 12.59 1,0000 3.973 1.457 008 0,029 VCV 12.73 i.0000 6,684 1.904 009 0,050 VCV 12.77 1.0000 1i.465 4.553 09.0 0.017 VCV 12.84 1.0000 3.879 1,505 Oii 0.004 VCV 12.93 1.0000 0.879 0.279 ei2 0.092 VCV 13,08 1.0000 21.285 7,835 013 0,075 VCB 13.18 1.0000 17.237 5.094 014 0.009 BCV 13.44 1.0000 2.022 0.719 015 0.011 VCV 13.48 1.0000 2.489 0,759 OiF.. 0.018 VCV 13.68 1.0000 4.069 0.736 0l.7 0.009 VCV 13.75 1.0000 2.010 0.577 01f: 0,007 VCV 13,83 1.0000 1.704 0.380 019 0.019 VCV 13.99 1.0000 4.408 1.395 020 0,046 VCV 14,10 1.0000 l0.582 3.109 021 0.017 VCV 14.24 1.0000 4.035 1.084 02."•' 0.012 VCV 14,37 l.0000 2,741 0,692 023 0.019 VCV 14,49 1.0000 4.406 f..514 024 0.030 VCV 14.54 1.0000 7.010 3.002 NICOTINE 2.792 VCV 14.76 1.2000 537.17i 237.194 02. 0.081 VCV i5.03 i.0000 18.765 4.098 026 0.019 VCV i5.ii 1.0000 4.444 0.879 027 0,028 VCV 15.22 1.0000 6.560 2.897 028 0.015 VCV 15.38 1.0000 3.356 0.645 0212 0.038 VCB 15.48 1.0000 8.757 3.782 WUINOL.INE=I3 BCB i5.66 1.0000 28.856 12.628 030 (1.015 BCV 15,92 1,0000 3.558 1.093 3.711 749.336
Page 112: nbi31d00
Areu Analyf•la f'il(;1..E2b7 V P207 t•i,°, 02:36t32 7/26/i985 Mthu; 45i :[tmt 45 Chnl 0 Vial # 0 8tnd/£npl % 0.125 M thds 451 V P207 M5 02t56t38 7/26/i985 Nume MG Pk RRT RRF Area Height 001 0.003 BCB 12.79 1.0000 0.941 0.372 00? 0.002 5CH 43.69 1.0000 0.577 0,272 003 0,007 BCB i4,ii i,0000 i.950 0,583 NICOTINE 1.141 PCP 14.76 1.2000 256,243 114.359 004 0.059 FCb i5.03 i.0000 iS.89f. 6.839 4UINOhT.NE"=I5 ErCB i5,66 1,0000 33.694 M439 1.338 309,296
Page 113: nbi31d00
Arec, Fsnulyt.i> Filr: ;l.C".270 V P207 TRL< 04:22t57 7/2b/i98+ MthW t 451 lnat 45 Chn'1 0 Vial # 0 5tnd/EMpl X 0.125 Mthcl; 451 V P207 TRC+ 04t43t03 7/2b/19EZ5 Nr.ime MG Pk RRT RRF Area Height NICOTINE 0.029 BCB 14.77 1.2000 5.970 2,677 WUINOLINF=IS NCB 5.5.66 i.0000 30.559 13.699 0.i54 3b.S2B
Page 114: nbi31d00
pp6oZcj 4- ~J+ 4-,Yf - ,Gc,oq. 1,ozcDi I. ~`' I - cJ~15$ s~d d~ - ,
Page 115: nbi31d00
E4TeR: 1=rUIT 3=BTOR Lti'CER ID 'i0 BE LIETE'J, 0.9 '(-;LL' FOR A LISTING OF ALL ID'S PRE6ENT W ii
Page 116: nbi31d00
Ar•ea Hrialyt.is f!'i l(: . LE264 IV P207 uS 00150111 7/26/i985 MthL;; 45i Inst 45 Chnl 0 Vial # 0 Stnd/Snpl X 0.i25 Mthd r 451 Nar.e- IV P207 SS MG Pk RRT RRF 01110 1 iB Area 7/26/i9fi5 Height DDi 0.007 VCB 12.03 1,0000 2.599 0.559 002 0.004 FlCV 12.33 i.0000 i,530 0.360 003 0.013 VCV 12.40 1.0000 4.966 0.637 004 0.060 VCB 12,77 1.0000 22.400 8.250 D05 0.0i0 BCV 13,i0 i,0000 3.821 1.338 006 0.032 VCV 13.i5 i.0000 1i.801 3.902 007 0.004 VCV 13,30 i.0000 1.543 0.304 OOf, 0.002 VCV 13.43 1.0000 0.752 0.258 009 0.002 VCV 13.5i 1.0000 0.754 0.229 Di0 0.012 VCV 13.68 5.0000 4.493 1.358 Dii 0.005 VCH i3.76 1.0060 1.804 0.672 Oic^ 0.023 $CB i4.i0 i,0000 8,544 3.701 05.3 0.007 BCV 14,38 1.0000 2.503 0,519 03.4 0.007 VCV i4,50 i,0000 2.616 0.773 015 0.007 VCV 14.55 1,0000 2.627 l..050 01.b 0.004 VCV i4.63 i.0000 i,675 0.52i NICOTINE 2.342 VCV 14.76 1.2000 727.B53 321.102 0i7 0.017 VCV 14.97 1.0000 6.261 i,582 Di8 0,108 VCV i5.03 1.0000 40.439 16.481 0i9 0.0i2 VCV i5,i5 1.0000 4.305 1.034 020 D.0i0 VCV i5.23 1.0000 31022 1,172 025 0.027 VCV i5.35 i.o0o0 io.038 2,042 022 0,075 VCV i5.47 i.0000 27.954 10.958 G1U1NOLINE"=iS VCV i5.66 i.0000 46.625 i5.92i 023 0,020 VCV i5,92 1.0000 7,390 1.537 2.935 949.115
Page 117: nbi31d00
Ar•eu Anuly.,is I`i1e;LE265 IV P207 TRA 0iiM38 7/26/i985 Mthd: 45S Inst 45 Chnl 0 Vial i 0 Stnd/SMp1 % 0.125 Mthd: 451 IV P207 TRA 0it45i46 7/26/1985 Nur•.e Mt> Pk RRT RRP Area Height 00i 0.013 VCV 12.03 1.0000 3.466 0.567 00? 0.020 VCV 12.16 1.0000 5,124 1.304 003 0.0ii VCV 12,26 1.0000 2.737 0.911 004 0.016 VCV 12.34 1.0000 4.084 1.092 005 0.016 VCV 12.42 1.0000 4.075 1.393 006 0.045 VCV 12.53 1.0000 11.806 3,422 007 0,020 VCV 12.59 1.0000 S,i44 1.597 OOEi 0,030 VCV 12.73 1.0000 7.714 2.127 009 0.037 VCV 12.78 1.0000 9.710 3.745 010 0.019 VCV 12.84 1.0000 5.033 1.782 01i 0.007 VCV 12.94 1.0000 1.821 O.S90 0ir' 0.086 VCV 13.08 1.0000 22.320 7,906 013 0,065 VCB 13.19 1.0000 16.798 4,589 014 0.007 HCV 13.44 i.0000 1.889 0.720 0i5 0.008 VCV i3.48 1.0000 2.190 0.763 01b 0.008 VCV 13.61 i.0000 2.006 0,524 0i7 0.009 VCV 13,69 1.0000 2.270 0,784 0 f. E; 0.006 VCV i3,75 1.0000 1.687 0,567 019 0.006 VCV i3,84 1.0000 1.431 0.383 020 0.017 VCV 13.99 i.0000 4.311 1.337 02i 0.036 VCV 14.11 1,0000 9,437 2.741 022 0.019 VCV 14.24 1.0000 5,057 1.171 023 0.013 VCV 14,37 1.0000 3,302 0.901 024 0.020 VCV 14.49 1.0000 5,125 1.752 025 0.025 VCV 14,54 1.0000 6.494 2.827 NICOTINE: 2.225 VCV 14.76 1.2000 481.843 212.094 026 0.060 VCV i5.03 1,0000 15.519 3,080 027 0.018 VCV 15.11 i,0000 4.554 0.914 028 0.021 VCV 15.23 1.0000 S.377 2,341 029 0.0i1 VCV 15.39 1.0000 2.885 0.624 030 0.028 VCB i5.48 1.0000 7.350 3.173 fdU1NOLINE= IS HCE SS.66 i.0000 32.477 i4,436 031 0,Oi2 BCV 15.91 1.0000 3.192 0.887 3.058 698.229
Page 118: nbi31d00
Area Auulya*ii. f"i1.~. ;1E26S V P207 TRA 03:47128 7/26/1985 Hthd; 451 Inst 45 Chnl 0 Vial # 0S1nd/Enpl Z 0.i25 Mthd: 451 V P207 TRA 04t07s37 7/26/1985 Nurse U01 MG 0.0i5 Pk VCV RRT 12.04 RRF 1.0000 Ar•ea 4.096 He iqht 0.Bi6 U 0 ':' 0.05.8 VCV 12,16 1.0000 4.882 1.346 003 0.011 VCV 12.26 1.0000 2.94S 0.958 004 0.016 VCV 12.33 i.0000 4.409 1.187 0 0'.:: 0.014 VCV f.2.42 1.0000 3.663. 1.435 OOE, 0.049 VCV i2.53 1.0000 13.082 3.665 007 0.0f.9 VCV 12.59 1.0000 5.02S 1.661 OOS1 0,030 VCV 12.72 1.0000 8.121 2,279 Q09 0.044 VCV 12,77 f..0000 11.847 4.722 (?S.0 0.019 VCV 12.B4 i.0000 5.120 1. 830 0.007 UCV 12.94 1.0000 1.788 0.614 01;:' 0.087 VCV 13,08 1.0000 23.132 8.412 05.3 0,072 VCV 13.18 1.0000 19.331 S.305 0 i. 4 0,01.^•. VCV 13,44 1.0000 3.111 0.926 0 7. 5 0.0i0 VCV 13.48 1.0000 2.609 0.670 01f., 0.011 VCV 13.68 1.0000 3.068 0.573 05.7 0.006 VCB 13.75 1.0000 1.595. 0.498 01Et 0.013 BCV 13.99 1.0000 3.349 1.149 019 0,043 VCV 14,10 l.0000 11.619 3.f.75 020 0.009 VCV 14,24 1.0000 2.5i5 1.000 0 2 3. 0,008 VCV 14.37 1.11000 2,137 0.633 022 0.Oi5 VCV 14,49 1.0000 3,994 1.499 023 0.021 VCB i4.54 1.0000 5.520 ~.'. . 788 NIC't]TINC:: 2.666 BL:V 14.76 1.2000 593.942 260,944 024 0.072 VCV iS.03 1.0000 19.230 4.093 US 0.021 VCV 15.12 i.0000 5.665 1.188 026 0,027 VCV 15.23 1.0000 7.102 3, 007 027 0.019 VCV 15.39 1.0000 4.992 0.864 028 0.042 VCV 15.48 1.0000 11,273 4.542 QU7 NOLINE'=7:',a VCB 15.66 1.0000 33.413 13,135 029 0,01.7 BCV iS.92 1.0000 4.672 1.245 3,539 827.243
Page 119: nbi31d00
1.1qj4 - I.I9u co i
Page 120: nbi31d00
~-fj-95 i Q2 ~ ~ L'c,ru~t 55 74 L~9ci~t ~nc}• I1474- l.l I~~ /, /s"s -~e r. mos-I. Ima /, /-7 2/ 1 23 ~ U3-,,Y i- 0 9 65- L I l~ 3 ~ 1R~~ - 134- 14-8 ( lfi s~d - i~c= 13,5 1, o`7 q ~Jau~r t I.uhJ-3 I. p9~~ t lJUYS
Page 121: nbi31d00
~r~~~- ro3~3o3977 rnEP f/~,~L~V~rCJIV`
Page 122: nbi31d00
Areu Hnalyt.ls Fi.lf..; LE26fi P9 t h c.l : 451 V P207 .r,$ Inst 45 Chnl 0 Vial # 03:11:59 7/26/1985 0 Stnd/6rtpl % 0.125 t4thd: 451 V Nnme P207 35 i1G Pk RRT RRF 03:32:06 Area 7/26/19875 Height 00i 0.008 VCB 12.04 1.0000 2.768 0.409 004 0.004 BCV 12.35 1.0000 1.461 0.394 003 0.011 VCB 12.40 1.0000 3.607 0.412 004 0.055 bCD 12.77 1.0000 i8.496 7.183 00S 0.033 BCV i3.i5 1.0000 11.072 2,880 00r.. 0.017 VCV 13.68 1.0000 5.769 0.956 007 0,004 VCB 13.76 1.0000 1.223 0.424 00E; 0.020 DCB 14.10 1.0000 6.613 2,797 009 0.004 BCV 14.38 1.0000 1.435 0.369 010 0.009 VCV 14,55 1,0000 3.010 0.610 01i 0.014 VCV 14.70 110000 4.668 1.467 N:CCCITTNE; 2.ii5 VCV 14,76 1.2000 595.014 263,895 012 0.122 VCV 15.03 1,0000 41.309 14.994 013 0.010 VCV i5.15 1.0000 3.277 0.777 014 0.008 VCV 15.23 1,0000 2.685 0.781 01!:; 0.024 VCV 15.35 1.0000 8.154 1,731 016 0.074 VCV i5.47 1,0000 24,836 10.177 QIJINOLINE=IB VCV l5.66 1,0000 42.192 15.223 00 0.017 VCV 15.92 i,0000 5.868 1.227 2.674 783.458
Page 123: nbi31d00
% QO-3, -,-Bol~- I 'I 1 °)Z°Cl'l iFor'r 9obo ~ ~~ ~^~ O-11Jb T~l t
Page 124: nbi31d00
V~kV 6cma~~ All - li~17+ ~. f a 009: + 1M54 1 1r`:~8l H(':+ 1....`f9 ? .Ji :+ 1. . ';5 9 A)+ i._0Li ? i :'C!1;+ 1. :'4' ? {li!i'_:+ 1.2152 8 . ~ 0_!::+ 1.!:++11 9 r!0A;+ 1. _.F4.1 ..a7" _.....H g ;R:+ I.~;rtr Q fi93;+ ..1:"IZE3>.9,. 0l.4:+ 1rrii~e~ e ili.s~f:} i.. ~`~~5(. 'd Ci1~:+ 1. '±56 Q ~ ~0'I i : + . i . Ms . 9 ..,8`+ 1....'°_•O _:3:+ i...'ti3 _'2U:+ 1._03 __:1:+ 1. . -45 ,.'.i:+ 1 .550 _'2i:+ 1...':Lll ,8:+ 1.=1f= 9 7: + 1 . :;G[1 9 A:+ 1...`_rr 9 034: + 1.3896 9 C::i5: + 1.413 9 9 ; 0331+ .1.1010 9 ~~. ±,6 a45 _5:9:+ 1...0a 9 3-tCs:+ 1.. 39 9 .9 _21: T 1.771 02:+ 1.... r3 9 A4:+ 1.M2 9 _44:+ 1. c'c 9 _e,:i ,~. __ ? _ ._ ~o~a : _'r,: I . : . 54 9 -.-?;+ I...:~C+~; e ..:.., ij: 'f' 1 . .. .7L ? ,_,... cl : + 1. .. , 0°} s °~U.+ 1 :=`.'~ Q 5}~'i~~... j y 1.1721 t
Page 125: nbi31d00
4R;3 . DWF vae~qh+ :- ~ 6ood 1~rah- N:iI;+ 002: + 003: + 03;4:+ 0051f n06: + 0'.! i : + r.+ il:i .609: + J:.0 :+ !i.I:+ :% 1 G: + ,0131 +,. r 0141 P 001 + . 14 :. 017,+ 0i8b+ {:1i:+ ;i,'_'[I;+ _ :1:+ i; 22; + _ ... i: + -:4:+ f_t.'' Ci : + -"a•:+ : + `1 . 1 '9: + L : + F:+ L. : + A:+ - ``A7+ 15; + ; ~~i6':+ ( \'2/ : + _ wtJ: + 0491 -+ .. - 2: + + .-'4:+ --75: + - A 6+ . ' / : + M:'F' 'i:.:; -J~r: + _,,.:~,~: + =1: o
Page 126: nbi31d00
C..LL_LT NEW DATA 2~wDIT/i_IST EX:SI-I1vG DATA .i=END PilOGI:AM VOUR :7TLE NAME 13 DRrT69 ------ 1 ENTER SAMPLE ID (8 CHAR MAX)1R1 _,4T:=R NUMBER OF CIGARETTES IN SAMPLE(129 MAX):5G =:4-~ ER *iDDE: 1.=DILUTED MODE 2=NON-DILUTED MODE READ STANDARD.TO CHECK DRAFT MACHINE .1~ READING 1:53 REAi)IN; 2:74 ~EADING 3:1 `" _N"Eil: 1=COLLECT-NEW DATA 2=EDIT/LIST EXISTING DATA 3=END PROGRAM :-,AVE ;.C DATA F'iL':9 SAVED. 'S- +.I1_- AT -cAG" OONE 7G G E~,~_ A\Ew GVE. :~:, FiLE't 1:3c aAV4J: i)it1=Tt:2 .D RF703 Dl1FT+)4. D:.FTC75 DR.` T:f;j i:'TV7 tiA:'!E YOU WaNT TO KILL _-.,-.Eij A 'J'"iD STUP THE PROGRAM T R AN 'W' TO KILL ALL FILES :=Ci)LLECT NEW DATA 2-r:D.','i/LIST E)tISTING DATA a='=ND PRDGRAm FILE NAi"lE IS DRFTOO :=R SAMPLE ID (8 CHAR MAX)IR1 ._.._ _': 5A ?LF_fl?• MAX).5'?
Page 127: nbi31d00
:,~ E kUIlvG READING READING RE.^DING READING ;'i~ADING READ.NG :rEADING READING ftEADiNu READING READING READING READING cEADING READING READING READING READING READING 31:0077 32:0080 33:0UG5 34:0078 35:0072 3G:0001 37:0064 38:0063 39:0071 40:0062 41:0071 42:0080 43:0061 44:0075 45:0066 46:0071 47:0071 48:0070 45:0076 50:0075 £NTER:'1=CONTINUE WITH ANOTHER 2=9TGP ENTER: 1=EDIT 2=LIST =:c".::!< ID TD BE LISTED, OR 'ALL' FOR A LISTING OF ALL ID'S PRESENT MODE: 2 ~1 READ: 50 DATE ENTERED: 7-1G-E'a ;cEADiNG # READING # READING
Page 128: nbi31d00
.-- y~ .~ •,P r0 -.J .7, _rs .r-. qa Pa ~. .n t0 ri i-.J rt, r_n Js r J t'O r» .~ •yi .,0 i r• ., n.r_ r a Pa rys -.J :r, r_n .P r_p f'P pj -_J rY, r_n ..F r_J T~l + i t -h -h t t t + t t t t t t t t . -4 •f- -F ,1 'F -t •F'ia -h + -h t ah -t -h •h -t t ~t +'t t t t ,^F 'h t tr,t -_,~.7rnrn.t.. rf,.pr- rq..i!rpr_irn.--.r_.I:D ..-.-.JPJrn.t:_ Fry r.} r0 ' _ .i' •.D ~i . !'J `-n ._n -'d Pi. -d •~A ._J •b at (w7 1`J-C. S-l••• .- I f~.. •tl •11 .n yj •p.~qJ ll~ .p'.JY •L •p C . . -.. .-. .~•, ~f., r0 .C. .r. ..1:_ Q, - A '''J '-. , ~ . W
Page 129: nbi31d00
01.170 READ ING 4G:0061 READIiV G 47:0078 X E A D I N G - 46:UD69 READING 49:0076 z A ING 50:00G7 caV"_R: 1=CONTINUE 3dITH ANOTHER ID 2=ST'0P ~:vTER: 1=EDIT 2=LIST 3=STOP ENT=R ID TO BE LISTED. OR 'AL,L' FOR A LISTING OF ALL ID'S PRESENT . . . . :R';~
Page 130: nbi31d00
2=NON-DILUTED MODE fiEAD STANDARD TO CHECK DRAFT MACHINE 1.<< . R=ADING 1:074 READING 2:0G3 READING 3:0G5 :T__ADI:VG 4:065 R---- AD':NLi 5:079 FlE'r3DIN3 G:064 READING 7:080 aEADING 8:070 READING S:OOGB READING 10:0080 READING BYE 11:1 DRAFT ENTER: 1=COLLECT NEW DATA 2=EDIT/LYST EXI,STI.NG.AAT,q;` 3=END PROGRAM 1 YQUR FILE NAME IS DRFTO1 Ei`v T Ei? SAMPLE ID (S CHAR MAX ) iR1 ENTER NUM$Ei2 OF CIGARETTES IN SAMPL4(128 MAX):50 SiV''ER MODE: 1=DI-lUTED MODE 2=NDN-DILUTED MODE -cAD STANDARD ~D CHECK DRAFT MACHINE .:1'r _^DI VG ec:lD:ivC, G :\ _AD'A N '_i READING READING 2~ADsNG _ADIU, .tiE-A N IG 7.:0013 "(0077 3:0077 4.00o^J 5.0064. G:0083 7:00S7 8:0072 9:0071 10:0078 c:...':tiG _Z':OC7i 13:00u7 ~~:?Di!vG ;4:G;J78 ;<~ADI:VG .t5:0075 ;EAL`IiNG 18:0070 READING 17:0085 '.2EADINLi 8:0078 4=ADINL; t==~Di!VG 18:0076 20:0053 ~ r 9 a AD:iV:i Z;:0073 OD S 4 :ADI;VG 23:0078 ~0 R~.-^.UING 24:0073 %o r READING 25:008B READING c^8:0083 <:_A"JZ:tia ^c7:0081 i
Page 131: nbi31d00
TI _ : 1R2 lhODE: 2 ~t READTN, # READING ------- ---- ------- ( 13 57. ( 44) 71. ( 2) 61. ( 45) 70. ( s) 67. ( 46) 81. ( 4) G4. ( 47) 79. ( 5) G6. ( 48) G9. ( G) 66. ( 49) 76. ( 7) 56. .( 50) 67. ( 8) 58. i 9) 75. ( 10) 69. ( 11) 63. ( 12) 61. c 13) 56. ( ( 14) 15) 73 . 65. ( 16). 65. ( 17) 53. ( 18) G9. ( 19) G2. ( 2 C~) 62. ; 21) 61. ( 22) GO. : 23 ) 61. 24) 58. : 25) 71. 2G) 5s. ': 7 ) ;~ 4 . # READ: 50 DATE ENTERED: # READING --- ------- AVIi = 6G.90 STD. DEV, = 7.462 RANGE: 59.44 TO 74.38 .3:[GIVATu!'2_ 7-16-85
Page 132: nbi31d00
!-CUi_L::;:;f P;=a DATA Z=EilFTi;..iS; 4.XIST0G L'A'I A 3:' EAil ?;tGi:,R'? Y ti T:(_cE ;:AMci W DRF;0S WI:. SAMPLE 10 (8 CI-:AR hiAk)1RAF ENTER NirME,i-R Clf' CI,iAfiI:T7ES IN ,iAMPLE(129 MAX):50 : N7:::2 MODE: 1-D1'LU1'ED MODE 2-PdDN-DILUTED MODE i{:=fi!f STANDARD TO CHECK DRAFT 1<< READING 1:0147 READING 2:h1B4 <EAilIiv G 3: 0148 ( tCAD 1NL" 4:;r118 :i`_'.A:j1NU 5:0130 E,>.D I:u: G:01 67 7:41a7 ,._!l:.W 8:0171 : WNu 8:01:34 :<EAD':N(; 10:0174• :2EAD1NC7 11:0131 iYLAi)INij 12:01GFS ._->DIN~. ?3:0148 .i_::`i::itiG 14:0184. n_ -`.D.W WLNS n ...;;J:NT QqV.`v..i ::a:0:iV dL'i:,:.o7 ;7:ti:i4j :11:01E3:3 RER:,:13 10:0135 R_:ADI".G 20:0175 i:c:RDInG 21:0134 :"tEADi4t' 22:0.S8 i:_ADiND 23:0132 2c:=:]ING :4:ti:76 0".:. : v_! 25:0:3) .-3;(,11,j6. ...:`.:i:N,: .._.-..r 0:=, 2 7:Ci:iJ 2L:p iJ4 G0:i142 1S:'.; : NCi 30:0175 J_r.ii .!1':.i 31:013:3 __AD1N: 32:0171 i0=;u I:'V:.i 33:0146 V.:.A. ;N :. .... A:.;Yc 3 4:01.8v J-_1: :Q. ,.......,_.Yw Jii, U1W ( E F;Dd l\"T :i7:013i VEnD_i1G 38:0174 R-_AD?;v., 39:014G WDlN[; 40: 0183 ':EA•'.:ING 41:0142 VQDTVG 42: 0177 . 0! MACHI NE-
Page 133: nbi31d00
OPEN USD :.47. 184, 7.4'i. 178. ( ~] ) 1:;U. 137. ( '1) 137, 171. . 5) 13.', 174. ( ;;) 131. i. 8 Ei . . 7) 14S. 184. ( 147. 187. ( °) 145. 183. 1") 13c+, : ' 75. ( 11; 134. 168. ( ..') 132. 176. ( 13) 130. 164. ( 14) 155. 194. ( ls~. 142. 178. ( 1G) 13G, 171. ( 27) 146. 180. 143. 184. , s\ 132. 174. 143. 703. \ + \ 1!_ / 142. 177. 130 . 17 1 . ) ~T~/ 1, (~ 1G1 • D 13':• 7tt• 13u. 1/:. . ~.~ I 3E i9fJ1:i_. I # READ: 50 DATE ZiVTt;REU: 7-•13-r5 DELP # OPEN t.L.S;:) ,B;.L.F # OPEN t;LSE) llaL° ---- ---- ---- -- 37. ( 44) 13J, 161. 23. 31. ( 45) 151. 185. 35. 37. ( 46) 14G. 184. 38. 34. ( 47) 143. 178. 35. 42. ( 48) 147. 180. 33. 37. C 48) 131. 171. 40. 35. ( 50) 141. 174, 33. 40. 38. 40. 34. 44. 34. 39. 34. 35. 34. 41. 2. 37• 35. 4;., 01, i, !. 130. . 7: . .i_i. :.4:-. ].7E;, :i ~, . . _, , 17c• ,.,.n, 11. 14F'. 33. 1=r:, 34. 14°\, 183. .jE;. 7.G1>. 30. aY. _7I. o_, ..70. .').. . .. ~i:.1 . .. i.• ., s .. • . . 1 .~.. .. , . ..1•C . .. v~ _\ . 1.~.... i. ~: . ). 4" 1 B3. HOLES OPEN: AVG .. 141.32 s°D. UEV, = 7.z8r.: I'rAN":=: 134.05 ": 0 148,60 N iJLEL; KOSE:.D: AVG = 177.70 STL'. I)i:W. = .X7 M W m W (i'AM:.. 170.43 TO 185.13 )EL.': A P: AVG = 36.4G STD. :7EV. - .418 m m m o, RAttiGE: 32.^4 z-0 40.80 sQNP rU:z~_
Page 134: nbi31d00
i.I~C'ti':_.:{_ A ^Pi,::.. N r w m 00 -4 ..: 1.~ :`.=lX 7 :6'~ m m m
Page 135: nbi31d00
y , ~~ ~e6oud- f _.1 + '.. ?S = __.4.+ _ _ V C. ~ _ 04: + i . .. ..~.j~: i _ . Ah: 9 _. ! 4. _ .'9: + ..i0:+ ~ .,I ':;i_I .. ~ j .1 ~+ .. I .., . a 0120.+: ~ . . i ~. .. ~. 03 ~Ln j +~.. . .I. . .'L2 q. . ~ 0k~'.: # 1 . 1`~ i ~9 .. ~€!A~T'S. kk 1:~44L5tsa ~ # J. h atr . r, ~ . ' '~ ~ , J~ l-.._~. g * '8y 0181,;+ 1.1 m 9 . {Ij..q:+ i iS- 25 s 0f[:0: f 1.340 a _:1:+ i. ...'rJi 9 _i:L:+ 1. . l~C: q -_-.3: +:+ 3. ::l~C: 74 ? _24:+ 1.-.=.' 9 0::rJ: + 1.308 a .2L+:+ i . i:j g n _ ? i4~.+ i... ~9: " "9:+ 1.. . %9 ? . ^~. + 1 . . 61 g : + L~y . -. ~ _ . . . . ..~:+ _....41 9 _33:+ ! .:.r_C 9 ti:=4e+ 1 . ='7 ? rr'z.+:+ 1... i 7f q M:.+':; 1r ! ;rjp Q (!pi+ 1.--53 ? Q ^s3:+ 1.1484 0<:~+. •+ i., 79 9 _ 5IQ:+ 1.. 1 + 1.. iP 9 7i2:+ 1. `;Q 9 _i4 ti:+ i.~:. f_i'.`.,t}:+ ... 08 ? 45D+ .... 175 ? -'+c,C+ . :1 ? 27 ~ . ^'i :+ . . . . F+ _T9:+ s OD T X ; f.15~4 ~ 54ddRs . u'ysq ~ I, 1308,AV 1.1900
Page 136: nbi31d00
TIT LE: 1R3 # READING , 1) 71. ( 2) 62. : 3) 61. ( 4• ) 62. ( 5) G7. : G) 72. ( 7) 74. t 8) 74. ( 9) 75. ; 10) 70. ( 11) 58. ( 12) 72. ( 13); (33. ( 14) 75. ( 15) B1. ( iG) 73. ( 17) 72. : 18) 73. ( 19) 63. ~i)) 67. ; 21) 74. ( 22) "l3. ( 23) 8G. ( 2'4) G3. ! 25) 78. :'7) 73 . L;,) 7?. 73. • f 1 / , 7S. . -2) 8'.a J 3 ) 02. ::4) (3e. c 35) 62. ~S) 76. : 37) 86. 3E) 73. J 53. c'0) L-"5. 41J 80. , « 77. ; 43) 74'. MpDE: 2 # READ: 50 DATE ENTERED: 7-16-85 # READING # READING ( 44) 69. ( 45) 75. ( 45) 66. ( 47) 73. ( 48) 59. f 43) 68. ( 50) 74. AVG = 70.76 6TD. DEV. = 7.350 RANGE: 63.41 TU 78.11 SIGNATURE
Page 137: nbi31d00
d015=E i8I"1=Z lIQ3=t ZU'GL 01 +rG'v9 :30Nd?J BEA'L = 'A3II 'Q1S 8G' IL = Diiti zo / E:' ''t/.~,i IL 'ZL 'BL 'SQ 'A8 'LL 'GL 'L8 'IB 'E8 'BS 'EL. 'GL 'b9 'EL 'ES '8L 'GL 'S9 'AL 'SL '8L 49 '8L 'SL '8L (AS ) (G3 ) 'iL ~L LS 'E8 '9L (8b 3 '~i~J 'IL 'IL '-CLti ) (9b )
Page 138: nbi31d00
SI3e8 ~r LJ T [ in
Page 139: nbi31d00
.__° iR4F M(]DE: # REAi?IN;^: # ( 1) 150. ( 44) ( 2) 146. ( 45) l 3) 149. ( 46) ( 4) 179. ( 47) ( 5) 151. ( 48) l 6) 153. ( 491 ( 7) 162. ( 50) l 8) 133. ( 9) 133. ( 1?) 143. ( 11) 148. ( 12) 136. ( 13) 175: ( 14) 147. ( 15) 166. ( i6). 139. ( 17) 167. ( 18) 197. ;3) 152. 20) 171. •' ' , 139 . c ..z) 142. ( 2`') . l 24J 148. ( 25) 143. c 2S ) 136. 178 . ::.7. .,~--. )aj. 2 # READ: 50 DATE ENTERED: 7-16-85 rEADING # READING 143. 125. 175. 137. 148. 138. 162. 1.i5. 13g. i. 4 6 . 147. 145'. 131. 148. AVG = 151.16 STD. DEV. = 16.603 RANGE: ).34.56 TO 167.76 S:[GNATLRE ----------------------- : --------
Page 140: nbi31d00
z_aUIN; 39:0053 REAUING 46:0065 :~77ADING - 41 :A06a .'YEADIU, 42:0077 tcAD3VG 43:0072 t=F? IRG 4k:00G9 _:~. C: .. -`u ^I'~In 45:0075 d A^_'IVG 46:0066 =A DIVG 47:0073 i'Eh`DIN?i 46':0059 ,?_AD~ iiVG 49:00G8 f< :ADING 50:0074 Ev7ER: 1=CGNTINUE WITH ANOTHER ID 2=STQ° ::iv71=EDIT 2=LIST 3=5TOP ~ ~i, ENTER ID TO BE LISTED, OR 'ALL' F0UA LISTIKG`'OF ALL ID'S PRESENT .,- st<3
Page 141: nbi31d00
32r -. 1i ] 1 ,tAD'.iN ;? 33:0140 :iEADING 34:0179 R=fi9:N, 35:.0135 ADING 3u:0135 7 ,^-,DivU J7:ii14G =. a 3a:0247 = 1^_' 39:0128 =AD;~Ci 40:0141 =rJlti, 41:0148 ~ ADINO 42:0131 Y=RDING 43:0148 READING 44:0143 :rEADING 45:0125 aH ADING 46:0175 'r~ADIN3 47:0137 i EADI,VG 48:0148 iSADINC 4S:0139 _rEADIVG 50:0162 ENTER: 1=CONTINUE WITH ANQTHER.ID 2=STOP ENTER:,I=EDIT Z=LIST 3=STOP Ti; SE LISTED: OR 'ALL' FOR A LISTING OF ALL ID'S PRESENT
Page 142: nbi31d00
::?^FT cNT_R: i=CQLLECT NEW DATA 2=EDIT/LIST EXISTING DATA 3=E'VD PROGRAM Yi)UR FILE NAME IS DRF'i'02 ENTER SAMPLE ID (8 CHAR MAX)IR2 ENTER NUMBER ClF CIGARETTES IN SAMPLE(129 MAX):50 =VTER MODE: 1=DILUTED MODE , 2=NON-DILUTED MODE READ STANDARD TO CHECK DRAFT MAChINE , 0114 , READING 1:0057r' READINC 2:0061 .^,EADINCi. 3:0067 READING 4:0064 READINC 5:0066 READING G:00G6 rEA2; iVC? 7:0056 !t3=;JIivL, 8:0056 R'EADING 9:0075 RE?DING 10:006J .<r=DlNG 11:0063 f3EADING 12:0061 R ~~ADaNG 13:0058 r=ADiMG 14:0073 =Dz5:0035 -tJ:N f~ lop,J065 ] \4c Ia: cs~ :~E ~- D INc <_:aDz`N:~ i,:ooG2 20:0062 :.EADSNG 21:0061 7 d?D":1VCi 22:0050 3Ep:.I\G 23:0051 J I N i; '<'4 : 0058 ,. . ~ , i:_-... '_'. 25. l>07i ~...ti' . 2, 3 : c_-05S i_'=Di vG 3V:007S -E~D1 iVG 31:0053 i-~^DIN: 32:0071 L" r+ _Af)IiVG 33:0061 w B ~ A;SNG 35:0079 m -.•".DiNu 36:fi069 ko a~AD G 37:007::7 A :?EADi.NG 38:0078 rEADivG 39:0069 ,<EADING 40:0068 ?=ADileG 41:0061 4::0075 i
Page 143: nbi31d00
r;' F;D::VG 45:014E3 I'tER:)INti 46:018a ;i'r;AD"tN;i 47:0134 =tEAI1_tVCi 48?0:78 VG 49:0136 .*t::AllIN i 50:017C 2~RL- iGG 51:0136 5z:01G5 ;-^~..:~~ 53:0138 =A'_;LN <: 54:0171 5ti:0140 R' ~DI;v S 5G:017G READIiVCi 57:0133 {lEADING 58:0178 R Ne 59:0148 AD LV 60 : 0176 iicAI,~TNG 61:0154 :1EAC7,NC 82:0187 RERDi1vG 83:0150 READING 64:0189 READING G5:0148 READING 6G:0181 READING G7:0142 READING GB:0176 READING 88:0145 - ,-Er'S MAKE A DEAL. YOU PRODUCE ONLY LOGICAL INPUT AND ! WIL)_ PRODUCE ONLY ABSOLUTELY CORRECT CALCULATIONS. THANK YOU SOCRATES RE A;) ::vCl Go :0145 RERDIN6 70:0183 A D IiY~t 71 :0132 li".5 72:O1G.r] =^.DIiV , 73:0139 74:01'77 ....a~ .... IC:.:~..:J. G c.AU...v i30:018. <_!aL:IVG Es:.::155. 6.^_:01:1'.'• 83:`?138 UI7:i 3 ac:,,:~J iy7..!3k. :',....: E~1S'a . .^~; N::i E13: o 1 i~.3 :'4:017F 8 :0147 96:0180 A,ilI~~:', 87:0131 :EniIING J8:0171 E .'-1:.) T .N Ce 99 : 0141 EP.DIN:a 100:0174 ~rUNT'INUE Y.I tH AN2Tt7..~.,1 1J
Page 144: nbi31d00
1=E D I T 2=LIST 3=ST0' nftAFT ENTER: 1=COLLECT NEW DATA 2=EDIT/LIST EXISTING DATA 3=END PROGRAM `.':7i.1f2 "LE NAME IS DRFT04 ENTER SAMPLE ID (8 CHAR MAX)iR4F ENTER NUMBER OF CIGARETTES IN.SAMPLE(128 MAX):S0 ENTER MODE: 1=DILUTED MODE 2=NON-DILUTED MODE READ STANDARD TO CHECK DRAFT MACHINE .<'EADItv , 1:0150 .REAilINi, 2:014G :7=ADING 3:0149 ir~ADING 4:0179 READING 5:0151 .,_.^-.:::N; G.053 MAKE A DEAL. Y,-~U PRODUCE ONLY LOGICAL INPUT AND ~ P:'tOD U':E ONLY AESOLL'TELY CORRECT CALyULATIONS. Tt?ANS. YOu St,CRA T ES <=^J ;ui; 7:O;G2 '~=^DING 8:0133 :2E~ IN 9:0133 zE ADIN G 10:0 143 AIi:iM1G ':::0:48 _N'_, _2 ::,, ?33 ti' 3:0175 47 i : uG i5:;.):l'ib i::C13:1 17:?1c37 =:=:DING 18:0197 ~: R:::iNG iJ:0152 3 E^J :V5 2L`:0171 En r'En~:.v~ 2.:0135 N _:0142 W m 23:D:58 00 :Y:=:-`,D;.`Ci 2 4:'.: 48 v w: vG 25:0143 m 3LAD-V3 Y.AD'N, 2G:013G 27:0178 m -d_ADI~N; 28:0137
Page 145: nbi31d00
:.VT:.R: I=EDIT 2=l.IST :3=STOP .=NTER: 1=CCLLECT NEW DATA ?=EDIT/LIST EXISTING DATA 3=END PROGRAM _ "9 U:; FILE NAME IS DRFT03 ENTER SAMPLE ID (8 CHAR MAY)1R3 ENTER NUMBER OF CIGARETTES IN SAMPLE(129!MAX):50 ENTER MODE: 1=DILUTED MODE 2=NGN-DILUTED MODE r "iE- AD STAN, D A R D TO CHECK DRAFT MACHINE _..,~ fEADING ~~=ADING ,iEADING R_ADING READ ItvG =Ai)LVG . :VL' dc'`;} I NU 1:0071 2:0062 3:0061 4:0062 5:0067 Cz : 0072 7: 0::74 d:0J74 0 :0" 75 F t: : C Ci 71J ;.; :::00 E3 12:C072 ~=:AD:N i =::0063 7cA DIN G 14:0075 fcADli~ , 15:0081 1^-u:0073 ,~„ r_. VG. 17:0072 - - :B:OC73 ~ 8: '< _ : ... . :4 ~_. o,-• . ! JI . r. L V. 6i ,. , 21 : 0074 ~ 22:0073 F~. m READIfv^, 23:0066 00 :1c.ADING 24:0063 REaDING 25:0078 ,{EADI:NG 26:0072 a J 4ING 27:0075 .:_AD . Nc, 28: r..062 DIN 3 28: 007i :NG 30:0073 ?=~;DING 31:0076 ?EAD I NG 32:0081 icADING 33:0082 :=An :aG 34:0088 =,uG 35:0062
Page 146: nbi31d00
r ~IC6~tF, ~S . S~c~ $/(l ~g~ i
Page 147: nbi31d00
~ w~, ° e~- 'A ^w' V'_. Z- f" f W,./ "'m N4 1 2R QZtGarv 30 , 3I h~,~{tia~ S~w ~
Page 148: nbi31d00
... I L . . ' I _4~i~tEADINO ~ f 1) "128.~ 1 2J•~131. i < 31~:136.) f -4/~•.128. I f 3) -125. ; f 6);id138. f -71s;~1,,Z8) f 81~~128. f ~~81r`.,~138. ' f 10)-}.M5. _ f 111rry133. .(Y2)• 133..". ~ ~ 128: '.l"141. 13S.kc. ~Stt) 127:'° `' (..18/ ,13~. ~ (..1"l;iyy137.'• ~ f 18);~{138:~ ( 18)'S$147. ' / 201. .,'.128. I 21)._:443... , f 22).~127. f 23) 131. ' ( 24) ~128. < 25) 132. / 281 . 128. ! 27)'133. - f 28)Vid30. l 2q1 ~'l128. i 1 30;+ 127.. < 317_ 143.- ( 321 , 133. ( 33)~. 131.--( 34137. . f 35)tS133. 1 38),,:.130.,. f 37) .;12D..f 3B); 123.f 3BY•..133. , f 40);`y140. • I 41)`i130. ( -42 ) 130. ( 43) ~41130. ENTER: 1•EDIT 2•LIST '3•STOP MOOE: .•2 M READ: S0t„ DATE /~READING -/- READING _ ' f 44) 136. f 451 133. f 461 114. ( 47) 125. ( 46) 127. ( 49) 134. ( 30) 131). ~ A'hkaa' ENTERED: 7-1'l-85 AVG • 132.18 STD.-DE6. _ •3.841 RANGE: 126.34 TO 138.02 ____ _________________________ u yM ® b J ~ w
Page 149: nbi31d00
~)4 - /3D 3 - ~ 6Jf
Page 150: nbi31d00
Q0. 125. 125. 133.. 140. 130. 130. 130. Ew'.-E''": i=?URiE ID 2=DELETE READING 3=N0 CHANGE ..N7ER: V._DIT 2=LIST 3=STDP -3 DRAFT ENTER: 1=CGLLECT NEW DATA 2=EDIT%LIST EXISTING DATA 3=END PROGRAM YOUR FILE NAME IS DRFTOS T_i SA ?~E :D (S CHAR MA}()EUDY _...:Z:; INUMSER OF CIGARETTES IN SAMPLE(,.9 MAX):5G _ X' "c:2 "ICCE: 1=DILUTED MUDE. 2=NCN-DILUTED MODE ._CK DRA=- "=;C4I NE .;U1.'.0' 2.o:3i 3=38 `.:' T NG 0: 012 G EA.a.tP:u 5.Olc'5 OA..iv: u:0136 ;=.,:)yN., 7:012s .>_A..`d3 i3:U129 2. _,IiV_ 0013E3 .:.014;.i _:0's33 2:01.35 :i 13:0128 `DItV3 14:0135 ::aAD::;VG 15:0227 V_:AD:::N'" ?. G:013n. :ro^,:`,1\G 17:0137 ..=-":i:)i.xi:, 18:0135 Kr '.J:014g PRODUCE C.~I-f , :I \ ~_.. _ ft^L 'VPLiT r: /~ Va
Page 151: nbi31d00
vuk-v~-rwf ubw~kVO'~,. ~ ~~ ~ w~ ~0 . ~~ l T" Zy. re i. Z 2 3 ~ ~ ~ G 7 ~ a LO < 2 hca~es o~ '~~ K , : eF4~ J~ , ~%e 1 1'21 3 -7l 0 Cu~ulti~l ~eC. awko " weC Coww ~df- w~u Prc ~j IV~Y~IG'~AO~ u
Page 152: nbi31d00
1:012a ~~:0131 3:D1~Q. 4:01'2G 5:0123 G:013G 7:012J 8:0129 J:013:] 20:0145 11:0133 1<^:0`<35 13:0128 14:0135 15:0127 1G:0134 17:0137 18:013G VWDIiuC 18:0145 :7ERDING 20:0129 READING 21:0143 READING 22:0127 slEADING 23:0131 READING fcr AD I NC? READING KRD1'NG MA/lI7V; ~-„„, :T~G~.u aX3 REAuin S._~''~~..~ . 1I.1/Vs ,._UM iMIh':i ^ A ,1 24:0128 25:0132 2a:0128 27:0133 28::J130 :.`3. V12° V 30.0127 31:0143 32:0133 33:0131 :?4 : 013'7 3,5:C133 36:l:_3c, :17:''v125 a~s: ;i2ci ... .`;J 1 v. 3.5 Mw i J :. .4l l J..,,I r. 0.30 s` D M ..:y'G 2:0:.'30 _ MM5 400130 4. 0. 0130 _.^....4o Lr']i :lY.D:3 {.!:')::4 %: ;':_2C "WL7N'':,tiUE W:':N ANWHER ID -.°5rCP ID T17 BE LISTED. OR 'ALL' FOR A LISTING OF ALL ID'S PREBG;+T
Page 153: nbi31d00
N 66,A~ 09 . -44. O.Pe m0r- 36 cL ~ ~ Zs~ d~v~c.c. w, cat- ej,Ue OS L w1. wIr -Wlu,ier _ ~~~~,,~~~~~~~ Wv~. ~11/~p1A61.& ~~ n . ~i~c.Wt __Q);cu+6k9. . v raaatxy li.elds dwiw j . ~ . I Ti,upwau,,- vu~ou~sue~ J~ w~. W;AL dlia9~., ca4u-19e,,/ ~ m m ~
Page 154: nbi31d00
O~F'I.-OFP I~mw'- or0acts -G pcu~ sl~¢ol wo~ _, N 5 wJl G~CQz gjo~~ -ao WVV4~w avio- V"W, ra%~46 VA4V~l co r~ ~~c~
Page 155: nbi31d00
6,16 ~8lP Cw 3. Uood.s ~ stt of gm~. 4, om VVI l 2s o•zl N ~ko ~ ~ `fmlro . 3•6,mlrR r&-h Ytw Sw
Page 156: nbi31d00
~ it UAA-~ NjAti/ I M. EP -a WY)oW cu~ lFomjt~ --"A- & pcf •u u
Page 157: nbi31d00
8'-12-8G lft'e w;6. ~w `D , UOoadS `PW~ VT (M) 30 - 35 Ce ~~CS => 25(.03 Z6z.?0 zss.a-r z6?0;s~ 71 i.~ 40 e77b~ $-a VI/0#, zko,q3-4- z,40 Czax) 1100, $1 ym/f& N i~ , e~brads _. a.ud~ , uw+efa, . o~ 3 bvt~.~ds GSV . c~ IJLS ~ d~~- oF' _ s~uola~ vu~,o~v~e; .TNS - 7* 1~ x~xac~ - tag* G~) Ln ~ ~ s~oeQ w~bo ~ st~s ~~rat~ad w1v OD C~5 w~' ~ Sha~w S lNr, m. ~ C07,
Page 158: nbi31d00
t Gik ~~ °:.ti3e~p I~QJ~r (ZT ruAA.S ., ~o~ voi~a i,ukw,uk~r, ~~p O` c~~ "[U G~I {,~ r ~1'CY ~fl . . `_4 kPr'P ~2 V' `AT `- . _.. _. ~.1.1"'"..... r %44A4-,(
Page 159: nbi31d00
qq~,, 2 4a4A p4 , . so w4 6rrAtl c u.) ~ pll~c, VOdf Co)d) I s4 vU~ 't u ~~ . a At ~ euQ, V Vl~~ ~ J~ •^^ ~eKve~ ( I 1 Z stQ& ?W~ ' ~ 6 pWir, voh u rt 4R( Il 4 Ok'd& F u t~ t• 4\ L" ( l, USRiAN'i.. . ~ - C .C
Page 160: nbi31d00
a~ -rk 1~gWA. t(/RrPW.~Z .. .. 19.VS . . . m Al 6.3g (0.45 91jal"7.a1 u m 6.?iF _ ... _. _ ~.61f htevel6t . S., 4a 4 „ 4,91 7,53 w _ oFF, pad RD 0.03 t~P o ~v ow, +4 0,013. 0 J A r . A '
Page 161: nbi31d00
~~ • S~OW~ 'FTC~ cgz~~i~,g 35 Zs2C. v4gq, ~ i Z5°F , foo 7o% , T~p~ ~ C~~ ~'ad~ o y w~*le,,,,
Page 162: nbi31d00
~064 ~~L", r ~~-- ~ ~~ ~ ~ ZS ,~Q ~~ 0 qP' ~~ 4 ~ 0~ ~5 3 3 Z7-: a a Z~ lab , zg 0 LYI r 5 ~ S - -X9---. 9 w a S . 3 a,5 --- OD ~ 5 • zy - -~. ~ b 6 . Q , Z -3-e -.. m ~ " r ~ ~ ~ ~.zy jJ Z 5 30 rA lo° 3f 8'- a 3 L ~ 9 l~ io I2 2 /3 3 20 ( R I ,--,, f,^.- to,., 4 S.T~-
Page 163: nbi31d00
fl~AMA~ ^?h'3C? J IMInSt.uia.t_ S'1 dfi , V ob•i,u,y.e,, 94.1 a O"k - z K kwv4t X ~--1AO,,ca,~,~ `~ G~eCeCs~aA~et^ e- Z ~. -s ~k
Page 164: nbi31d00
44.30 1 66.00 2 85.10 1 120.10 1 45.50 1 67.10 2 86.10 1 131.10 1 50.10 16 68.00 4 87.00 1 143.20 1 51.10 25 69.10 1 88.00 1 145.10 55 52.10 7 71.10 1 89.10 4 146.10 64 53.00 2 72.00 1 90.10 5 147.10 7 54.10 1 72.50 1
Page 165: nbi31d00
g'1g~8~ ~~ &&A ~~N i u81dr - (0 pu(& 0, 08 aX o. oK 803g± 0 2 '' . 0,01 0_,035"_. 0,0035 0.000Z4 3 " 0,68 O'K ~ ~-lo 0.0-7 o3s O 0.003T , . ooft± o S " 0, 0-7 4,035 . 0.0035 0.0017. (o O.o55 0.0055 ~ fl~{,~ol - t9 O.O~k o;0y . e.ooa 8 « 0.03 O.o~ . o.aorr z 0,0015 ( 0.oaoiq R & M .0,03 o,ot~ C1z OOOtS I} , 10 30 ~S 0.2A 0.1p 0,0033 ( 0.0030 I I a 04 Q,0$ _ 0;602? 13 ~30 20 _"a"`"" 0, 0,0033. (0.0056 " O ZZ ~ O,II 0 0031 . II~ I~w~el - 36 0 ,13 . . 6,065 0,0027, 0 001q , „ a.o9 0,046 0015 0 . ESP of'F - ~ pA 6 2c~ ~ 0. 0 ue4k 'I~` v VW i, ~ ?~ livedw - ~ G") '' I'S "ol - lQ
Page 166: nbi31d00
iaowi FuOK ,nfto elb puf -~ - PR UeAIue, - . Use, yt`"a" ~- 7~ . Z ~u~uds C4o) ~ "~ ot _ po~ds TUAX ~ T* 2 Il Put~ ~ ~ ~u~ 2 2 2 ~2 ?- 3 3 13 3 s s If i5 5 ~ G . . IL_ ~6 ? ? n .? 8 8 . B R q ca. a '~rm IF. G~oOks (`DM) . ..- ..__t.- _ (IS~, nWE~, l'DItiu~Vc~ .~i ^ W143~ ta1&"~ d'4'1' st ~ ~ ~ ~o -80 Tr~ ) w ( Vc~oQ~(-(~.r*
Page 167: nbi31d00
9-(Z-k fkv., E*ae,r6 oW" -4m N(00 ual ri~,r -tv WtV4 ., 1 sa&Q(c.. . V"svbt ~V~ 5o ,IJ- 'uo"Aa., d'w 11Jg 23~ - z 3 hta,u#"t ~ WAA w - " ,z KO-L Wv~ to:,( r*-~ .. 6w"&4&~ "J- otel
Page 168: nbi31d00
AM- w~Vlk~a;EiM reuku,w.d.. (mt(,rme, do.uolyd d,ts~vi bc~cov~ ~ ev- QuAbmt, D~nw - mutawd "~ n... ,Ccwad t ry_ _,~ ? ~CI~ ~ ~ d.~~1aUc~W' 1/S , a~ ~~1'w+tcu681ti l~c~n ~ecu~r~t~ ~ d~c+d(tv~2 ev~ircu2~ Vewr~ _ q1 ~ ~. tl~oooGs - ~ _ Ckd- Wl R1z , tm-Z 4er' C4 , I
Page 169: nbi31d00
Data file: DATA:EAKEA01A.0 File type: GC / MS DATA FILE Name Info: REGULAR Misc Info: #10 Operator : JNS Date : 20 Aug 86 2:00 pm Instrment: MS_5970 Inlet : GC Sequence index : I Als bottle num : 1 Replicate num . 1 Tf r IY C P1 FT R. - qk! RIA t R• P1 4.6EE'1 3. 0E6 I 2.DE67 GRAPHICSCO [MS2] TIC of DATA:EAKEA0IA.D MOPC-- 4® TI me ...Ijo..~ 96 100 T: TIC of DATA:SCHUAIIA.D Z: TIC of DRTR:SCHURIfA.D Y: TIC of DATR:ERKER8IA.D 1(: TIC of DATA:ERKEA0IA.D REGULAR Peak.# Ret Time Type Width Area Start Time End Time 1 21.907 BV 0.166 54873063 21.688 22.197 2 24.029 BV 0.142 12559049 23.853 24.230 3 29.458 VV 0.177 99786655 29.220 29.826 4 30.749 PV 0.166 20969956 30.544 31.043 5 31.872 B8 0.136 51512608 31.682 32.090 6 52.418 BB 0.114 176630531 52.170 52.619 7 56.852 BB 0.194 362534197 56.597 57.300 8 66.254 BU 0.117 59535068 66.072 66.361 9 66.454 VV 0.113 51231644 66.361 66.635 10 66.866 UB 0.154 58335329 66.635 67.189 11 71.641 BV 0.123 49742334 71.455 71.779 12 76.898 BV 0.176 77516208 76.628 77.204 13 82.702 VV 0.276 873699536 81.822 82.715 14 82.848 VU 0.142 455975B84 82.715 83.157
Page 170: nbi31d00
TOTAL AREA=3.8187E+87 NUL FACTOR=1.8888E+88 RUN # 1184 AUG 14, 1986 16:61:18 START ~ ;~. ,., ~~~~~ 9./22 13.897 STOP - 3.945 - 5.487 -18.641 - 11.825 Error storins sisnal to M:SIGHALy:. RAY ATTEIIPTEO YRITE PAST END OF Fl Stvrins Processed aeaks to M :Q3 DIRECTORY FULL RUN# 1184 AUG 14. AREA% i RT AREA TYPE MIDTH AREAk .546 853 4963 BV .488 5.18495 .958 725 8429 VH .348. 4.48947 1.180 6427 3312 SHH .978 39.,84578 1.913 18 0362 TBY .143 .18957 2.465 23 3798 TVY .169 .14283 2.628 18 7378 TVV .896 .11383 2.795 46 2788 TYV .185 .28189 3.271 41 8919 TYP .284 .25449 3.618 11 4177 TPY .871 .86936 3.722 15 1517 TVB .878 .89265 3.945 4505 2192 SHH .449 27.36982 4.238 4 3722 TBV .849 .82656 4.370 73 6415 TW .213 .44737 4.648 42 7659 TW .143 ,25988 5.487 1819 4192 iSHB .273 11:85298 7.475 13 2839 ; BV j!y.886 .88821 7.688 88 1828 I YP , :177 .53578 iWiEtiWO '4* f 1986 16:81:% SAMPLE# 3
Page 171: nbi31d00
oct Iey3/N Fr .283 .96644 ,R54 389536 VP .441 .23664 .*41 4586592 . PB .134 2.78634 'S 4126018 PB .136 2.58654 ~.y7 2595181 PP .164 1.57651 792635 _:: . PY :..'82 : . 492.:; ' :,48152 , .. e65 1647686:. -VV , -.599 1 00096 6 625 1111589..'YV .279 .67529 431 1968329 VV .421 1.19575 T:-AL AREA=1.6461E+88 MllL FACTOR=1.8888E+98 RUN 1 1185', AUG 14. 1986 16:24:36 START 1 I STOP Error storing sisnal to MsSIGHAL RAY ATTE1lPTED YRITE PAST END OF FILE Storins aracessed Peaks to M:Q31A8DCS.PRO DIRECTORY FULL RUHt 1105 AUG 14. 1986 16:24:36 SAMPLEI 4 AREAX RT AREA TYPE YIDTH AREAB .448 ._.617677 8P .178 7.78129 3.811 ,77429 PY .289 .96540 5.872 67882 PV .183 .84636 6.832 632200 W .188 7.88236 18.663 1723833 PB .147 21149388 11.585 649878 ,BV .128 8,09270 11.845 . 326979 1VP .139 4.07682 13.145 279837 PP .398 3.'47988 13.928 3646333 PY .247 45.46299 TOTAL AREA=8928438 MUL FACTOR=1.9888E+88 ABORTED e
Page 172: nbi31d00
s~~ ~ sv C~) tA~ aA 13 bctl~-l,3 -dael ~o,tzs ~ ~rvm~ T-r M~~ D0,v'L --2,3`Ghev&c, o d¢e.auaA aA4 Z?.f5 ~rro~ -2- e~rl~e saI uu~ mbwNa. ffvowvwm -2, 0 113 ~ tn ~ " m OD Ivy) . . , . , V . m N X ke"A41 "6WOK4, x S-W4•oV~e. Nsl3 N'o ~~ ~ KV-1 .
Page 173: nbi31d00
43.10 4 67.20 1 98.10 100 146.20 1 44.10 2 68.10 6 99.10 6 147.10 8 45.10 1 69.10 7 104.10 4 148.10 2 50.10 8 70.10 6 105.10 3 161.10 1 51.10 17 71.10 1 106.10 3 175.10 10 52.10 8 74.10 1 116.10 1 176.10 33 53.10 2 75.00 1 117.10 6 177.10 4 54.10 2 76.10 2 118.10 14
Page 174: nbi31d00
LIBRARY SEARCH RESULTS Scan 1752 (29.453 Nin) of DATA:EAKEA01A.0 REGULAR Library file: OATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: PARA-CYMENE 0 2: BENZ.ONITRILE,4-HYDROXY- 0 3: PYRIDINE,2-METHYL-S-VINYL- 0 4: PYRAZINE,ieo-PROPENYL- 0 5: PYRIOINE,S-METHYL-2-VINYL- (SBB 2510) 0 6: BENZOXAZOLE 0 7: ACETOPHENONE, 4- METHYL- 0 8: PYRIDINE,3-ISOPROPENYL- 0 9: 5H-CYCLOPENTAPYRAZINE,6,7-OIHYDRO-S-Me- 0 10: CYCLOPENTAPYRIZINE-SH,6,7-DIHYDRD- 0 c 3 100 50 0 GRAPHICSCA IMS21 can 1752 (29.459 m1n) 77 83 226 7800 1596 7778 537 7504 1118 7479 539 7096 92 6617 1688 6611 52? 6605 589 6461 1105 6332 oF ORTR!ERKER01R.0 1 147 ti.. k226 PRP.R-CYHENE 91 ~ 134 161 20~45 100 I. :~ k1596 BENYONITRItLE,4-HYpROXY- R9 E4 91 I, ~ a, ~ 1I S s ik537 PYRIOINE,2-HETHYL-5-VINYL- 51 91 ~ s I 1'19 { l. J l ll +--i~-~---r- 40 60 B0 100 120 140 160 160 200 Mars/Charge L00 100 50 T: nu1l. Z: Scan 1327 (24.029 min) of Y: T1C of DATA:EAKEADIA.D X: Set of 4 MS Scan 1752 (29.453 min) of DATA:EAKEA0IA,D ,N/- C c D 'Faue REGULAR m/z abund. m/z abund. N/z abund. ro/ z abund. 28.1 0 9 67.00 10 93.10 36 122. 10 3 29.1 0 13 68.10 3 94.10 S 128. 20 3 32.1 0 2 69.10 19 95.10 4 131. 10 3 39.1 0 19 70.10 5 103.10 3 133. 10 7 41.1 0 49 71.10 4 105.10 31 134. 10 5 42.1 0 6 77.00 24 106.10 6 135. 20 3 43.1 0 12 78.10 5 107.20 6 136. 10 7 51.1 0 6 79.10 15 108.10 5 147. 20 10 52.1 0 3 80.10 4 109.20 6 148. 20 6 53.1 0 16 $1.10 9 115.10 5 161. 10 21
Page 175: nbi31d00
43.10 3 67.10 1 94.10 1 145.10 1 44.20 2 68.10 6 98.10 100 146.20 2 45.10 1 69.10 7 99.10 5 147.10 8 50.10 8 70.10 7 103.20 1 148.10 2 51.10 17 71.10 1 104.10 3 161.00 1 52.10 7 73.10 1 105.10 3 175.10 9 53.00 2 74.00 1 106.10 3 176.10 31 54.10 2 75.00 1 116.20 1 177.10 4
Page 176: nbi31d00
55.10 55 82.10 6 117.10 56.10 14 83.10 7 119.10 57.10 15 91.10 59 120.20 65.00 25 92.10 27 121.10 66.20 6 93.10 50 LIBRARY SEARCH RESULTS Scan 2902 (52.411 min) of DATA:EAKEA0IA.D REGULAR 11 148.20 6 100 161.10 11 20 189.10 10 49 204.20 22 t~y q/ /oS 9y 123 /00 Fr9 >z sy J'2 Library file; DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: TRIACETIN 0 235 9986 2: 2(3H)-FURANONE,2-ACETOXY-4,5-DIHYDRO- 0 674 9860 3: ACETOL 0 192 9852 4: ACETIC ACID,2-OXOPROPYL ESTER 0 727 9852 5: GLYCERIN,mono-acetate 0 728 9847 6: ACETIC ACID,2-FORMYLOXY-3-HOPROP ESTER 0 717 9844 7: MII-Vc 0 43 9839 8: PYRUVALDEHYDE 0 799 9805 9: ACETIC ANHYDRIDE 0 1386 9793 10: ACETIC ANHYDRIDE 0 1731 9783 Scan 2902 (52.411 min) of ORTRcERKER01R.0 10~~ 29 ..L. 93... . ~ ID~` 1,f6 14~1r100 LII---p66i 0235 TRIRCETIN ~ IWD1I [" 74 101~ 116 14_ 100 4 3 C N a 0674 2i3H)-PIJRRNONE,2-RCETOXY-4,5-DIHYORO- ~ 360 ~ r106 ~n 43 72 f F i6192 RCETOL 102 3 ~ Fk100 50~ I 43 74 6 --* 0 20 40 60 66 101a 120 140 Maea/Charge GRRPH]CSCD [MS2] Scan 2902 (52.411 min) of DATA:EAKEA01A.D REGULAR m/z abund. m/z abund. 28.10 1 29.10 2 31.10 1 39.10 1 41.20 1 T: null. Z: Scan 1940 (31.866 min) of Y: TIC of DATA:ERKER0IA.D X: Set of 4 MS m/z abund. m/z abund. 43.10 100 57.00 44.10 3 61.00 45.10 1 73.00 55.10 1 74.00 56.00 1 86,00 1 103,10 11 1 115.10 3 1 116.10 4 1 145.10 9 1 146.10 1
Page 177: nbi31d00
LIBRARY SEARCH RESULTS Scan 1327 (24.029 min) of DATA:EAKEA0IA.D REGULAR Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS 1: OCTADECANOL 2: UNDECANOL 3: GERANIOL, TETRAHYDRO- 4: GERANIOL, TETRAHYDRO- 5: NONYL ALCOHOL 6: CYCLOHEXANONE, 4-HYDROXY-2,2,6-TRIMETHYL : PYRAN-2-ONE(3H),4-ISOPROYL-6-ME-5,6-HYDR HEPTANOL-1 9: OCTANDL-1 10: FURANONE-2(3H), 4- ISOPROPYL- CAS # Library Index # Match Quality 0 1818 9755 0 1765 9675 0 1795 9444 0 1781 9315 0 1771 9264 0 1717 8735 0 1671 8162 0 1548 8149 0 1546 8142 0 1787 8123 Scan 13E7 (24.029 min) nf ORTR:ERKER0IR.0 i00 ~ 69 63 97 11l I 100 29 lil l'41 iT1 T~ li~~l i~l ~I ~J ' 0 100 IP1B1B OCTRO ECRNOL 5 100 i m u ~ ,0 13 ~~~ ~P ~3 `~ I ~ `0 C 0j M 100 N176S IJNOE CRNOL r100 83 97 tl S 41 61795 GERRNIOL. TETRRHYORO - 100 100 ~~ 84 57^ 50 I 3 110 / ~ \ 0 0 ~r T 1 ~ 1 I I --~- `0 30 40 50 60 70 80 90 100 110 Muss/Charge GRRPH]CSCO [MS27 T: null. Z: Scan 1161 (21.906 min) of Y: TIC of DRTR:ERKERDIR.D X: Set of 4 MS Scan 1327 (24.029 min) of DATA:EAKEA0IA.D .p REGULAR m/z abund. m/z a bun d. m/z abund. m/ z abund. 28.20 28 42.10 21 57.10 48 82. 20 13 y 29 10 46 43 10 61 67.10 17 83. 10 38 co . 32.00 14 . 53.00 13 68.00 10 84. 10 15 m 4b 39.10 32 54.20 19 69.10 37 97. 10 24 40.20 16 55.00 68 70.10 35 111. 20 14 m w 41.10 100 56.10 44 71.10 19 w
Page 178: nbi31d00
LIBRARY SEARCH RESULTS Scan 3248 (56.848 min) of DATA:EAKEA0IA.D REGULAR Library file: DATA:TDBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Index # 1: MYOSMINE 0 10 2: COUMARIN 0 1861 3: PYRROLE[I,2a7PYRAZINE,3,6-DIMETHYL- 0 1371 4: BENZONITRILE,2-AMINO- 0 1488 5: BENZIMIDAZOLE 0 95 6: IMIDAZOE1,2aIPYRIDINE 0 968 7: TETRALONE-1 0 834 8: BENZIMIDAZOLE 0 614 9: PYRIDINE,2-(1-PROPENYL)- (S8B 236D) 0 543 10: PYRIDINE,3-CYANO-4-METHYL- (SWW 100D) 0 275 5can 324B (56.B46 mtn) of ORTR:ERKERBIR.O 3 9 5 1 7 6 10 5 11312 `++. / 'Lq! I. . ald~~.. di.......~~u~..~....~.d.. .....~n~.~.il. . 18 146 .I N10 MYOSMINE 51 78 1PJ~5~ d f-' 116 146 II k1B61 COLIMRRIN 63 _ 64 69 ~ : II _-, 11 "1116 146 Ip1371 PYRROLEC1.ZaJPYRRZINE.3.6-OIMETHYL- / 1Gi© 39 1134 118 / 1~m 5© ~ ` 51 _. / 146 ~50 6 I I I ~ ~ € 0 213 413 6m 80 100 120 140 MacriChargs T: null. Z: Scan 2902 (52.411 min) of GRRPHICSCO Y: TIC of DRTA:ERKER0IR.D [MS23 X: Set of 4 MS Match Quality 9865 7502 7331 7257 7072 6941 6913 6896 6837 6548 Scan 3248 (56.848 min) of DATA:EAKEAOIA.0 REGULAR m/z abund. m/z abund. m/z abund. m/z abund. 28.10 17 56.10 2 72.90 1 91. 10 11 29.10 1 56.10 1 74.10 2 92. 10 3 32.00 1 57.10 2 75.00 3 93. 10 1 37.10 4 58.60 2 76.00 7 103. 10 2 38.10 10 60.10 1 77.10 10 104. 10 8 39.10 25 61.10 3 78.00 24 105. 10 19 40.10 9 62.00 7 79.00 2 106. 10 2 41.10 24 63.00 16 80.10 1 116. 20 2 42.10 15 64.00 10 83.10 1 118. 10 100 43.f0 4 65.00 15 84.00 1 119. 10 9
Page 179: nbi31d00
LIBRARY SEARCH RESULTS Scan 1940 (31.866 min) of DATA:EAKEA0IA.D REGULAR Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: BETA-IONOL 0 58 6495 2: PARA-CYMENE 0 226 5617 3: BENZONITRILE,4-HYDROXY- 0 1596 5585 4: PYRIDINE,2-METHYL-5-VINYL- 0 537 5475 5: ACETOPHENONE, 4- METHYL- 0 1688 5295 6: PYRIDINE,5-METHYL-2-VINYL- (SBB 251D) 0 539 5261 7: BENZALDEHYOE,4-ISOPROPYL- 0 1408 5220 8: Kd 0 17 9184 9: BENZOXAZOLE 0 92 5063 10: PYRAZINE,iso-PROPENYL- 0 1118 5027 Scan 1940 C^s1.B66 mIn) of DRTReERKER01R.0 ~ ,~ 111111 5~,1,1 I,ia. 133 058 BETR-IONOL /b226 PRRR-CYMENE 91 ~ 134 I 01596 BENZDNITRILE.4-HYOROXY- 100 CF160 50~ 39 E4 91 119 f.'SB R33 T I a. 1 J I I 1 I rrr~~~f0 40 60 B0 11313 120 1413 162 1B0 200 Mass/Charpe ._.__ GRAPHICSCO CMS2I T: null. Z: Scan 1853 (30.748 min) of Y: TIC of DRTA:ERKEADIA.D X: Set of 4 MS Scan 1940 (31.866 min) of DATA:EAKEA0IA.D /SaF+r''of oF .l~ C ~' q.PC°4' d REGULAR m/z abund. m/z abund. m/z abund. m/ z abund. 28.20 21 67.00 21 94.10 21 122. 20 14 29.10 43 68.10 7 95.10 20 123. 10 57 39.10 42 69.10 35 103.10 9 124. 20 7 40.20 13 70.20 7 105.10 72 128. 10 7 41.10 89 71.10 10 106.10 18 129. 20 6 42.20 14 77.00 39 107.10 36 131. 10 7 43.10 32 78.10 11 108.10 10 133. 10 38 51.10 13 79.10 44 109.10 21 134. 20 10 52.10 6 80.10 15 111.10 22 135. 20 6 53. f 0 3 f 81.f0 31 115.10 16 147. 20 14
Page 180: nbi31d00
LIBRARY SEARCH RESULTS Scan 3978 (66.259 min) of DATA:EAKEA0IA.D REGULAR Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: BENZOPHENONE 0 1798 9939 2: BENZOIC ACID, METYL ESTER 0 1544 8775 3: PROPIOPHENONE 0 176 8733 4: BENZIL 0 802 8714 5: BENZOIC ACID, ETHYL ESTER 0 1543 8597 6: ACETOPHENONE 0 440 8526 7: PHTHALIDE 0 1841 8345 8: PHTHALIDE 0 54 8202 9: BENZYALDEHYDE 0 57 7898 10: BENZAMIDE 0 181 7735 Scan 3976 (66.^c59 10015~+ ~ .,,., "5l. 0 100~ J0 In) of ORTR:ERKER01R.p sm5 / I6r? I k1796 BENZOPHENONE 50 _ 11 ~ ~"`~~ 5 1 7 7 1111 5 i 01544 BENZOIC 50_ 51 ~~ 11 1 ~1 77 152 RCIO. METYL ESTER IP0 5 136 j 100 162 ~I "0i #17E PROPIOPHENONE 00 1003 50 51 77 124 L5 50~~i-''~ i 05 \ 0 0 -r-. ^-~-.-.-.---r--- ~ `^-r----r t 40 60 60 100 120 142 160 160 Hass/Char6e T: null. Z: Scan 3248 (56.848 min) of GP,APHIC:SCD Y: TIC of DATA:ERKEADIA.D [MS2] X: Set of 4 MS Scan 3978 (66.259 rain) of DATA:EAKEA0IA.D UK REGULAR m/z abund. m/z abund. m/z abund, m/ z abund. 28.1 0 3 51.10 51 71.10 3 105. 10 100 29.2 0 3 52.10 4 73.10 2 106. 10 9 ~ 32 0 0 1 53 00 1 74 00 6 151 10 2 4i . 38.1 0 2 . 55.10 4 . 75.00 . 5 152. 10 6 m 00 39.1 0 6 56.10 2 77.00 82 153. 20 3 .1 ~ ~ 41.1 0 4 57.10 5 78.00 6 154. 10 3 0 42.2 0 2 62.00 2 83.10 2 181. 10 12 43.1 0 5 63.00 4 97.10 2 182. 10 61 50.1 0 19 69.10 3 98.10 1 183. 10 8
Page 181: nbi31d00
55.10 21 82.10 3 117.10 56.00 10 83.10 3 119.10 57.00 5 91.10 31 120.10 65.00 10 92.10 14 121.10 66.00 3 LIBRARY SEARCH RESULTS Scan 1853 (30.748 min) of DATA:EAKEA0IA.D REGULAR Library file: OATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CRS # 1: NONA-2,4-DIENAL 0 2: PENTEN-4-AL,2-METHYL- 0 3: OCTEN-6-AL,3,7-DIMETHYL- 0 4: PENTENAMIDE-3, 4-METHYL- 0 5: GERANIOL 0 6: NEROLIDOL 0 7: NONA-2,6-DIEN-1-OL 0 8: NEROL 0 9: PYRIDINE,3-(4-METHYL-3-PENTENYL)- 0 10: FARNESOL 0 Soan 1853 (30.74B min) of ORTR:ERKER01R.0 160 ~ 28 ~ 0 II 10m 1 2 c 10R, 3 I ~ , rd leo3 50~ 0 Library Index # 1447 1460 1453 1343 1554 1612 1773 1774 272 1827 91 133 1013 X 2@4 ~ ~ J~il ~r~ill ~d I a I iI6 J~pi k1447 NONR-2,4-DIENAL rlpp 1 1 'lf ~I PENTEN-4-AL.2-METHYL- 69 I 1 / #1453 OCTEN-6-RL.3.7-OIHETHYL- ~ 100 50 50 100 15B 200 Mass/Charye T: null. Z: Scan 1752 (29.453 min) of GRAPHICSCO Y: T1C of DATA:EAKEAOfA.D [MS2] X: Set of 4 MS Scan 1853 (30.748 min) of DATA:EAKEA0IA.D 4 4 18 4 Match Quality 7364 7132 6876 6756 6692 6612 6600 6599 6596 6271 . ~ . ~a y w REGULAR m/z abund. m/z abund. m/z abund. m/z aqGnd. ut ~ 28.10 28 53.10 34 71.10 20 105.10 29 w 29.20 24 55.00 49 77.00 34 119.10 20 ~ 00 32.10 17 56.10 21 79.10 32 120.10 21 39.10 39 57.10 30 81.10 26 121.10 ~ 13 m 40.20 15 65.10 14 91.10 41 133.10 31 w 41.10 100 67.00 28 92.10 22 161.10 m 62 43.10 29 69.10 46 93.10 39 204.20 21 51.20 13 .70.10 14 / 4 9 l 9 ?~,P/ / ~e a y6 6 2 y/ -'7 6 162.10 100 189.10 15 204.20 15 205.10
Page 182: nbi31d00
57.10 100 84.10 10 125.20 LIBRARY SEARCH RESULTS Scan 4396 (71.640 min) of DATA:EAKEA0IA.D REGULAR Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS (SR 1840 ) CAS # Library Match Index # Quality 2: 3: 4: 5: 7: 9: 10: GERANIOL, TETRAHYDRO- GERANIOL, TETRAHYDRO- ACETAMIDE,N-ALLYL- NONYL ALCOHOL BUTANONE-2, 3,3-DIMETHYL-4-HYDROXY- UNDECANDL HEXANAL OCTADECANOL. SUGAR DIANHYDRIDE ACETAMIDE,N-(2-PROPENYL)- IBmJ 0 6 1781 8586 1795 8454 747 8427 1771 8332 1721 8313 1765 8233 1438 8211 1818 8093 869 8033 1321 7917 :can 439E (71.E40 m1n) of oRTR:ERKER01R.0 /~ ,`~ IE9 169 241 _ 340 r1R0 4 3i1. /k17B1 GERRNIOL, TETRRHYORO- Ik179S GERRNIOL. TETRRHYORO- 100 50 GRRPHICSCO [MS2] ,,,,{{ 4 1 l6 I I ~ ~ k747 RCETRHIDE. N-RLLYL- J I I \ 99 49 I 57 / 1m0 E00 30m MasciCharme T: null. Z: Scan 4025 (66.867 min) of Y: TIC of DRTR:ERKEAOIR.D X: Set of 4 MS Scan 4396 (71.640 min) of DATA:EAKEA0IA.D REGULAR m/z abLind . m/z abund. m/z abund. m/ z abund. vt ~ 28.20 1 5 57.10 86 85.10 17 117. 20 7 m 29.20 4 6 58.10 5 87.00 7 125. 20 10 ao 31.10 4 60.00 21 95.10 7 129. 10 20 ~ 32.10 4 61.00 14 96.10 8 139. 20 7 ~ 39.10 1 0 67.10 13 97.10 27 171. 10 6 w 41.10 8 8 68.10 8 98.10 10 185. 20 16 42.20 2 5 69.10 35 99.10 6 227. 25 5 43.10 10 0 70.10 17 101.00 9 241. 35 12 44.10 5 71.10 26 109.20 4 267. 35 24 45.10 6 73.00 26 110.20 5 284. 45 11
Page 183: nbi31d00
44.10 2 74.10 3 111.10 10 203.10 16 45.10 5 75.00 3 115.10 30 204.10 2 50.10 6 76.00 3 116.10 2 213.15 2 51.10 7 77.00 4 LIBRARY SEARCH RESULTS Scan 4025 (66.867 min) of DATA:EAKEA0IA.D REGULAR Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: HYDROCARBON 0 32 9361 2: TETRADECANE 0 1846 9258 3: 3-HEXANONE 0 469 9090 4: TRIDECANAL 0 1478 8359 5: PYRROLIDIN-2-CARBOXALDEHYOE 0 1474 8129 6: PYRAN-2-ONE,3,4,5,6-TETRAHYDRO-4-OH- 0 709 8011 7: 1,3-DIOXOLAN-2-ONE,4-METHYL- 0 730 8004 8: FURANONE-2(3H), 4,5-HYORO-3,3-DIME-4-HO- 0 1647 7755 9: PENTADECANAL 0 1454 7732 10: SUGAR DIANHYDRIOE (SR 1770) 0 867 7672 100JI ,111 Scar, 4025 [6B.BE7 rnI n) oP ARTRtERKER0IR.C) r ~ {I ~ 99 155 1B3 Ii".t~00100 7 111 Ik32 100 ~ 99 0] ~7 I i11 k1B46 10~JI ~s 1! ~1 I 0 CRRPH)CSCD [MS2I 250 T: null. Z: Scan 3993 (66.453 min) of Y: TIC of DRTA:EAKEADIA.D X: Set of 4 MS Scan 4025 (66.867 min) of DATA:EAKEA0IA.D C,~V P~.P,T REGULAR m/z abund. m/z abund. m/z abund. m/ z abund. 28.1 0 9 58.10 6 85.10 41 126. 30 5 29.1 0 23 67.10 7 86.10 4 127. 20 10 39.1 0 5 68.10 6 96.10 4 141. 20 7 N 41 1 0 52 69 10 20 97 10 12 154 20 3 P . 42.2 0 18 . 70.10 IS . 98.10 . 5 155. 10 7 w m 00 43.1 0 99 71.10 65 99 10 16 168 20 3 ~ 44.2 0 4 72.10 4 . 110.20 . 3 169. 20 5 m ~ 53.1 0 3 81.10 4 111.20 7 183. 20 5 N 55.1 0 42 82.20 4 112.20 5 197. 20 3 56.f 0 22 83.10 13 113.20 12 267. 35 3 HYDROCRRBON TETRRDECRNE IF469 9-HEXRNONE 71 100 ^ i 1 1 T 50 1013 150 200 HissiCharpe
Page 184: nbi31d00
17 66.979 BV 0.103 60243591 66.810 67.171 18 71.258 VV 0.139 67606938 71.060 71.411 19 76.490 VV 0.233 100058067 76.167 76.869 20 82.383 BV 0.356 1175475188 81.414 82.540 21 93.457 PV 0.173 36482051 93.082 93.470 22 93.565 VV 0.083 24696781 93.470 93.583 23 93.599 VB 0.213 S0311755 93.583 94.080
Page 185: nbi31d00
~~ (U~ vuUtrC'iMQ. W~ 4~ Nd W`0 ~P 2} ~ evko vs pnolt -mEva¢t wcd~ fU¢* (6'r C#LCty) Q4 iSB~YO~~ - "$ - -VU{;, ) nS CNL&o 3) 9~'K'bltlr fsrOUf - "AM AW ktC..? ~ (W"tyeot) .+) ~'f uf-~ -'Pvk uaco~ ..,(Wa4W) Eirl~a~2d ~O ~1~s o~_ .eaQG~- oP~ ~ -(~c8 . ~ ^'Z~ r~l IUe.O(~ rD1"1 40 N 59 wkQ , a& 00 wW-: r ~a a~~ie,na~ ~0 utA.w~ ~ s«lb- 4D AW'5 ~s --~ 4D ~W4, -biplMOIX ruA ~ 2M@. oF 3 " e~ - to - f 0nt ,tiw,&.~u. ~ X e~aw*4 , ~w pad.., 0 hAlceqr. ew~ p4 Lw w~a lQea~uol I . auvA -jo Tw ? u ", ? so pu~`c~qt es~buu~uR dwW stt (Stt ~ Z 2b3, V~> oN ~ 2 ~ ~3P Off . . . . J m N LTI
Page 186: nbi31d00
44.70 1 64.00 10 86.00 1 131.10 2 45.30 1 65.00 14 87.00 1 143.30 1 45.60 1 66.10 2 88.10 1 145.20 57 49.20 2 67.10 2 89.10 5 146.10 63 50.10 16 68.10 3 90.10 5 147.10 6
Page 187: nbi31d00
LIBRARY SEARCH RESULTS Scan 5266 (82.849 min) of DATA:EAKEA0IA.D REGULAR Library fi1e: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CRS S Library Match Index II Quality 1: COTININE 0 12 9763 2: N-METHYL ANABASINE (SWW 2D) 0 237 9215 3: PIPERIDINE,1-ETHYL- 0 1136 8800 4: 1,5-DIMETHYL-2-PYRROLIOINONE 0 40 8716 5: NORNICOTINE,N-ETHYL- (SL 390) 0 878 8211 6: PYRROLIDIN-2-ONE,1,5-OIMETHYL- 0 1378 8108 7: PYRIDINE,3-(1-ET-2-PYRROLIDINYL)- 0 999 7877 8: PIPERIDINE,1-METHYL- 1 1143 7345 9: PIPERIDINE,2,3-DIMETHYL- 1 1139 6791 10: 2-PIPERIDONE,6-METHYL- 0 787 8770 Scan 5266 C62.B49 m1n) of ORTR:ERKER0IR.D 42 51 ~"' 119 147 178 ~'10p I,,. .a.d,. ~,..., .,... i. as .. I . n .. ... .I. 144~ ,~ 012 COTININE 100 42 ~ 116 147 176 {r100 ~.+..~ ~ pJ I 9B I d~i ~ i~L~p c m a 6237 N-METHYL RNRBRSINE (SHN 20) ~ IppJ 42 70 I, 119 ('100 C ~ i 9Bi ~I 01136 PIPERIOINE.1-ETHYL- 100~ I [[''100 42 66 { S 50 1 6 ~50 I 3SSS 0 ' I FFe 0 20 40 60 B0 100 120 140 160 _ MassiCharpa T: null. - 2: Scan 5255 (82.702 min) of GP.RPH]CSCD Y: TIC of DRTA:EAKERSIA.D [MS2I K: Set of 4 MS Scan 5266 (82.849 min) of DATA:EAKEA01A.0 REGULAR m/z abund. m/z abund. m/z abund. m/ z abund. 28.1 0 18 55.00 4 76.00 2 117. 10 6 vt ~' 29.1 0 3 56.00 3 77.10 4 118. 10 14 m 30.1 0 3 67.10 1 78.10 10 119. 10 16 0° 31.1 0 1 58.00 1 79.00 5 120. 10 4 ~ 37.1 0 1 61.00 1 80.10 4 121. 10 7 a 38.10 4 62.00 3 89.10 2 122. 20 1 J 39.10 13 63.00 8 90.10 2 123. 00 1 40.20 3 64.10 4 91.10 6 131. 10 1 41.10 16 65.10 8 92.10 4 132.1 0 1 42.(0 30 66.00 2 93.10 2 133. 10 2
Page 188: nbi31d00
LIBRARY SEARCH RESULTS Scan 5255 (82.702 min) of DATA:EAKEA0IA.D REGULAR Library file; OATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS 1: COTININE 2: N-METHYL ANABASINE (SWW 2D) 3: PIPERIDINE,1-ETHYL- 4: 1,5-DIMETHYL-2-PYRROLIDINONE 5: NORNICOTINE,N-ETHYL- (SL 39D) 6: PYRROLIDIN-2-ONE,1,5-DIMETHYL- 7: PYRIDINE,3-(1-ET-2-PYRROLIDINYL)- 8: PIPERIDINE,1-METHYL- 9: PIPERIDINE,2,3-DIMETHYL- 10: 2-PIPERIDONE,6-METHYL- Scan 5255 (62.702 mtn) of 42 51 ~ . / g ~... CAS # Library Match Index # Quality 0 12 9741 0 237 9157 0 1136 8747 0 40 8676 0 878 8170 0 1378 8073 0 999 7840 1 1143 7340 1 1.139 6818 0 787 6797 ORTReERKERB1R.0 119 147 176 r10m .u.,. .... .,. . i~ © "\ 012 COTININE 42 116 147 I / 9B tll. ~ R237 N-METHYL RNRBR/SINE (SWW 20) 42 713 / 119 ~i 9Bi II 01136 PIPERICIINE.1-ETHYL- 1®0 / 10B 50 4% 96 ~ 112 50 0 0 20 40 66 66 100 120 140 160 Mass/Char6e T: null. Z: Scan 4805 (76.897 min) of GRAPHICSCO Y: TIC of DATR:EAftERD1A.D [M52] X: Set of 4 MS Scan 5255 REGULAR (82.702 min) of DATA:EAKE A0IA.D m/z ebund. m/z abu nd. m/z abund, m/ z abund. 28.10 18 55.00 5 77.10 4 119. 10 15 29.10 3 56.00 2 78.00 11 120. 10 3 30.10 3 57.10 1 79.10 6 121. 10 8 31.10 1 58.00 1 80.00 4 122. 10 1 37.10 1 61.00 1 89.10 2 123. 10 1 38.10 4 62.00 3 90.10 2 131. 10 1 39.10 13 63.00 8 91.10 7 132. 10 1 40.20 3 64.10 3 92.10 5 133. 10 2 41.20 17 65.10 9 93.00 1 134. 20 1 42.10 33 66.10 3 94.10 1 145. 20 1
Page 189: nbi31d00
LIBRARY SEARCH RESULTS Scan 1154 (21.833 min) of DATA:EAKEA03A.0 LIGHTS (CONC.) Library file: DATA:TOBACCO.L Library name: T08ACCO AND SMOKE COMPONENTS I : TETRADECANE 2: 3-HEXANONE 3: PENTADECANAL 4: TRIDECANAL S: PYRAN-2-ONE,3,4,5,6-TETRAHYDRO-4-OH- 6: HYDROCARBON 7: NONANAL 8: FURANONE-2(3H), 4,5-HYDRO-3,3-DIME-4-HO- 9: PYRROLIDIN-2-CARBOXALDEHYDE 10: CYCLOHEXANONE-1,2-DIOL, 4-METHYL- 57 , I Scan 1154 (21.833 min) of DRTA!EAKER133R.G 85 113 1 Ise 1130 4 Q ia OIB48 TLTRROECANE B5 11313 loci 50 la 3 0469 3-HEXANONE #1454 PENTADECANRL 82 57 1 / 1846 9964 469 6827 1454 8764 1478 8760 709 8391 32 8354 1434 8214 1647 8151 1474 8100 1660 8074 0 4 0 Go 80 1130 1213 14 la I E 13 IBM Masi/Charys GRAPHICSCO IMS21 T; null, Z: TIC of DRTA:EAKER03F.D Y: TIC of DATA:ERKEA03A.D X: Set of 4 MS Scan 1154 (21.833 min) of DATA:EAKEA03A.D LIGHTS (CONC.) m/z abu nd. m/z abund. m/z abund, m/z abund. 28.20 10 53.00 S 70.10 12 112.20 3 29.10 39 55.10 29 71.10 55 113.10 4 32.10 3 56.10 21 72.10 3 126.20 2 39.10 is 57.10 100 83.10 S 127.10 3 41 .10 67 58.00 4 84.20 6 140.20 3 42.20 19 67.00 3 8S.10 28 141.20 2 43.10 87 68.20 3 98.10 S 198.30 4 44.10 3 69.10 99.10 6 CAS # Library Match Index # Quality
Page 190: nbi31d00
LIBRARY SEARCH RESULTS Scan 1161 (21.906 min) of DATA:EAKEA0IA.D REGULAR Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS 1: TETRADECANE 2: 3-HEXANONE 3: PENTADECANAL 4: TRIDECANAL 5: PYRAN-2-ONE,3,4,5,6-TETRAHYDRO-4-OH- 6: HYDROCARBON 7: NONANAL 8: FURANDNE-2(3H), 4,5-HYDRO-3,3-DIME-4-HO- 9: PYRROLIDIN-2-CARBOXALDEHYDE 10: CYCLOHEXANONE-1,2-DIOL, 4-METHYL- CAS ik Library Match Index # Quality 0 1846 9989 0 469 8861 0 1454 8797 0 1478 8709 0 709 8374 0 32 8262 0 1434 8251 0 1647 8130 0 1474 8063 0 1660 7979 Scan 1161 (21.906 mtn) of ORTR:ERKER01R.0 100' 100 6 S 9 9 1 2 6 „Ii . 7 I Jil 41 i I~ , 43 I ,~ 1 k1646 TETRROECRNE 10~, I 41 Y143 III 57 if 71 ~ Y r'00 u c ¢ 0469 9-HEXRNONE 41 ~ ~„~ 71 43 I 57 I. I k1454 PENTRDECRNRL 1 ' ~i I` ^...,,,. 6 E 50~ 41 ' 43 ~ 57 o - --L ! , 1 1 1 - , 1 40 60 60 100 120 _ Mass/Char~n T: null. Z: TIC of DRTR:ERKERDIR.D GRRPHICSCD Y: TIC of DRTAaERKERDIR,D [MS27 X: Set of 4 MS Scan 1161 (21.906 min) of DATA:EAKEAOIA.D c,p p /t'. T, REGULAR m/z abund. m/z abund. m/z abund. m/ z abund. 28.10 15 53.10 5 69.10 8 97. 10 5 2.9.10 42 54.20 5 70.10 15 98. 10 6 32.00 4 55.10 28 71.10 ~6 99. 10 8 39.10 19 56.10 24 82.20 4 112. 20 4 41.10 71 57.10 99 83.10 5 113. 20 5 42,20 22 58.10 5 84.10 7 126. 20 6 43.10 100 67.10 4 85.10 _42 127. 20 4 44.20 5
Page 191: nbi31d00
Data file: DATA:EAKEA03A.D File type: GC / MS DATA FILE Name Info: LIGHTS (CONC.) Misc Info: 3ML M+OFF 32-36,42-46 Operator : JNS Date : 21 Aug 86 2:04 pm Instrment: MS_5970 Inlet : GC Sequence index : Als bottle num : Replicate num TIC of ORTR:EAKER03R.0 4.BE6 3.BE6 I.BE6 0 GRAPH)CSCD [MS21 TIC of DATA:EAKEA03A.D T: Scan 6089 (93.484 min) of Z: TIC of DATA:EAKERD2A.D Y: TIC of DATA:ERKERD3A.D X: TIC of DATA:ERKERD3A.D LIGHTS Peak# (CONC.) Ret Time Type Width Area Start Time End Time 1 21.838 BU 0.160 76764743 21.576 22.145 2 23.864 BB 0.126 21281654 23.676 24.168 3 41.973 BB 0.063 3693221 41.744 42.046 4 50.072 BU 0.128 11921931 49.570 50.167 5 56.496 PU 0.222 395732190 56.145 56.970 6 57.604 BV 0.178 63366742 57.256 57.772 7 57.904 UV 0.076 18780440 57.772 57.914 8 57.949 VV 0.118 25468656 57.914 58.094 9 58.242 VU 0.142 45641475 58.094 58.458 10 59.807 BV 0.123 39123567 59.574 60.009 11 60.952 VV 0.177 105937969 60.765 61.325 12 63.171 BV 0.132 44230954 62.974 63.377 13 64.644 VV 0.189 113915680 64.335 64.879 14 64.997 UV 0.093 20088077 64.879 65.152 15 65.859 8V 0.130 69410764 65.678 66.026 IF F6.452 VU 0.134 39780866 66.255 66_RFq
Page 192: nbi31d00
LIBRARY SEARCH RESULTS Scan 3993 (66.453 min) of DATA:EAKEA0IA.D REGULAR Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: QUINOLINE,2,4-DIMETHYL- 0 1040 8988 2: QUINOLINE,C2-ALKYL- 0 1039 8609 3: QUINOLINE,2,6-DIMETHYL- (SBB 257D) 0 558 8603 4: QUINDLINE,DIMETHYL (SBB 1730) 0 559 8589 5: QUINOLINE,4-ETHYL- 0 564 8434 6: QUINOLINE,5,6-DIMETHYL- (SBB 2310) 0 662 8159 7: QUINOLINE,2,8-DIMETHYL- (SBB 2300) 0 561 8066 8: 1-NAPHTHALENOL-TETROHYDRO-TRIMETHYL 0 33 7071 9: QUINOXALINE,DIMETHYL- (SBB 174) 0 609 6491 10: QUINOLINE,2-ETHYL- (SBB 242D) 0 563 6379 ¢ 10@ 50 0 5can 3993 (66.4 29 43 B7 115 13@ ~~, 203f'00 _ I`000~ 51040 QLIINOLINE.2.4-DIt4ETHYL- 42 79 115 128 ` 157 k1039 QUINOLINE.C2-RLKYL- 7 115 142 I I li 15 k558 QIJINOLINE.2.6-OIMETHYL- 63 115 (SBB 2570) 142 2 II 1 9 7 T: null. Z: Scan 3978 (66.259 min) of 50 100 150 MassiCharOe GRRPH]CSC-0 Y: T]C of DRTA:ERKERDIB.D [MS2] X: Set of 4 MS /S7 leo ~~ 3u Scan 3993 (66.453 min) of DATA:EAKEA0IA.D REGUL.AR m/z abund, m/z abund. m/z abund. n/ z abund. 28.20 10 52.10 4 78.00 5 128. 20 4 29.10 38 55.10 5 79.10 3 129. 10 9 30.10 2 56.00 5 83.10 2 130. 10 9 31.10 4 57.10 6 84.00 4 139. 10 4 38.10 2 60.00 4 85.10 2 155. 10 15 39.10 4 61.00 3 87.00 8 156. 10 26 40.10 2 63.00 2 88.10 4 157. 00 100 41.20 5 69.00 8 102.10 2 158. 00 9 42.10 12 70.10 3 104.20 3 159. 00 2 43.10 Z6 71.10 3 105.10 3 185. 10 2 5S mtn) of DRTR:ERKER0IR.D 7
Page 193: nbi31d00
53.20 6 81.10 13 111.10 54.10 12 82.20 9 112.20 55.10 75 83.10 31 115.10 56.10 98 84.10 10 116.10 LIBRARY SEARCH RESULTS Scan 4805 (76.897 min) of OATA:EAKEA0IA.D REGULAR Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS 1: 2: 3: 4: 5: 6: 7: 8: 9: 10: NICOTINAMIDE,N-METHYL (SWW27D) PYRIDINE,3-PROPIONYL- PYRIDINE,4-PROPIONYL- 3-ACETYLPYRIDINE PYRIDINE,3-BUTYRYL NICOTINAMIDE PYRIDINE,4-ACETYL- BENZOXAZDLE,2,4-DIMETHYL- 3-PYRIDINECARBOXALDEHYDE (NICOTINALDEHYD KETONE,CYCLOPROPYL-3-PYRIDYL (SWW 116D) 100 0 CAS # Scan 4605 (76.897 m1n) cf ORTReERKER01R.0 I, 6,~~.~.~ TII 71 107 ~. ~., .i . . " .~i ~76 ~` j!. 106 ~ 1351 I u250 NICOTINRMIOE,N-METHYL S5WWZ70) 51 ~ --..... / li J 76 I 106 195 II 18 285.35 49 4 266.35 10 6 340.45 15 12 341.45 5 Library Match Index # Quality 250 9369 476 8900 1613 8239 38 7561 306 7094 759 7063 475 6970 1185 6637 173 6561 297 6459 /F476 PYRIOINE.3-PROPIONYL- 40 N ~ 135 ('00 IL~~ ,I1 I 78 106 I &1619 PYRIqINE.4-PROPIONYL- 100 28 51 78 ~ 195 100 50:U.,f~ II I. ' 106 ~ E5 0 40 60 80 100 120 Mass/Cherpe GRRPHICSCO CMS2I T: null. Z: Scan 4396 (71.640 min) of Y: TIC of DRTA:ERKERDIA.D X: Set of 4 MS Scan 4805 (76.897 min) of DATA:EAKEA0IA.D REGULAR m/z abund. m/z abu nd. m/z abund. m/ z abund. 28.10 25 44.10 3 58.00 11 80. 00 2 29.10 7 45.10 6 67.10 2 105. 10 19 30.10 4 49.10 7 69.00 2 106. 10 63 37.10 5 50.10 41 71.10 2 107. 10 7 38.10 7 51.10 66 75.00 5 123. 10 22 39.10 8 52.10 21 76.10 6 124. 10 3 40.10 3 53.00 10 77.10 18 135. 10 61 41.10 4 54.10 2 78.00 100 136. 10 26 42.10 2 55.10 3 79.00 12 137. 00 3 43.2O 4 57.r0 4
Page 194: nbi31d00
LIBRARY SEARCH RESULTS Scan 3306 (57.604 min) of DATA:EAKEA03A.D LIGHTS (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMDKE COMPONENTS CA5 # Library Match Index # Quality 1: OCTRDECANOL 0 1818 9782 2: UNDECANOL 0 1765 9360 3: GERANIOL, TETRAHYDRO- 0 1795 8878 4: NONYL ALCOHOL 0 1771 8719 5: GERANIOL, TETRAHYDRO- 0 1781 8631 6: CYCLOHEXANONE, 4-HYDROXY-2,2,6-TRIMETHYL 0 1717 8309 7: OLEIC ACID, METHYL ESTER 0 1736 8022 8: CYCLOHEXANONE,2,3-EPOXY-3,5,5-TRIMETHYL- 0 1526 7874 9: HEPTANONE-2, 5-ISOPROPYL-7,4-OXIDE-(8V-2 0 1748 7836 10: TRIDECANAL 0 1478 7834 Scan 3306 (57.604 m1n) of DRTR:ERKER09R.0 100 I sE ~4 i l i 1 5 9 41616 OCTRDECRNOL, ` 3 ~, 111 I 1 i9 ~ ~ r100 10 1000, 11 ~ I II9 I M1765 UNDECRNOI. k1795 GERRNIOL. TETRRHYDRO- GRRPHICSCO EMS2] T: null. Z: Scan 3222 (56.500 min) of Y: TIC of DRTR:EAKEA03R.D X: Set of 4 MS Scan 3306 (57.604 min) of DATA:EAKEA03A.D LIGHTS (C m/z ONC.) abund. m/z abund. m/z abund. m/ z abund. 28.10 16 57.10 61 82.10 19 110. 20 7 29.10 39 65.00 6 83.10 47 111. 20 27 39.10 16 67.10 24 84.10 16 112. 20 7 41.10 84 68.10 14 85.10 19 124. 20 6 42.20 20 69.10 51 95.10 7 125. 20 15 43.10 82 70.10 30 96.10 11 126. 20 8 51.10 8 71.10 28 97.10 46 139. 20 8 53.10 10 78.00 S 98.10 11 153. 30 5 54.10 29 79.00 7 99.20 5 159. 10 12 55.10 100 81.10 10 105.10 6 308. 45 11 100 ^^--. I 7 6 j0 50 AAA1 II 4 1 , e 50 100 150 2021 250 900 HassiChark®.._____
Page 195: nbi31d00
LIBRARY SEARCH RESULTS Scan 2410 (41.974 min) of DATA:EAKEA03A.D LIGHTS (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: TETRADECANE 2: 3-HEXANONE 3: HYDROCARBON 4: TRIDECANAL 5: PENTADECANAL 6: PYRROLIDIN-2-CARBOXALDEHYDE 7: FURANONE-2(3H), 4,5-HYDRO-3,3-DIME-4-HO- 8: PYRAN-2-ONE,3,4,5,6-TETRAHYDRO-4-OH- 9: CYCLOHEXANONE-1,2-DIOL, 4-METHYL- 10: 1,3-DIOXOLAN-2-ONE,4-METHYL- Scan 2410 (41.974 GRAPHICSCD [MS2] 43 ~ gr m1n) of ORTReERKER08R.D 6 5 99 113 141 ~ 43 II J 57 11 01646 7ETRR13EC I BS RNE r100 6469 3-HEXRNO NE 43 I F~ 111 i S7 ( 71 / k32 HYOROCRRB 100 / ON r100 ~ tl~ 127 9 9 100 4 I 9 7 ~ 11 71 1 I f i l I 1/ 3 -~------ ` 0 r 0 40 60 80 100 120 14 MassiCharke 0 T: null. Z: Scan 1313 (23.868 min) of Y: TIC of DATA:EAKEAD3A.D X: Set of 4 MS Scan 2410 (41.974 min) of DATA:EAKEA03A.D ~' 7• C.Pyu ~ C b' /9 C LIGHTS (CONC.) m/z abun d. m/z abund, m/z abund. m/z abund. 28.10 12 54.00 6 10 69 14 85 10 37 u N w 29.10 34 55.00 30 . 70.10 14 . 99.10 13 m w 39.10 13 56.10 20 71.10 60 112.20 6 ~ 41.10 63 57.10 100 72.10 5 113.20 9 m 42.20 21 58.10 6 83.10 7 127.20 5 (/l w 43.10 92 67.10 5 84.10 8 141.20 6 44.20 5 1846 9815 469 8948 32 8812 1478 8662 1454 8611 1474 8Z76 1647 8098 709 8071 1660 7961 730 7875
Page 196: nbi31d00
LIBRARY SEARCH RESULTS Scan 3854 (64.648 min) of DATA:EAKEA03A.D LIGHTS (CONC.) Library file: DATA:TOBACCO,L Library name: TOBACCO AND SMOKE COMPONENTS CAS 4 Library Match Index >< Quality 1: GERANIOL, TETRAHYORO- 0 1781 8306 2: BUTANONE-2, 3,3-DIMETHYL-4-HYDROXY- 0 1721 8298 3: NONYL ALCOHOL 0 1771 8253 4: GERANIOL, TETRAHYDRO- 0 1795 8222 5: HEXANAL 0 1438 8194 6: PYRAN-2-ONE(2H),6,6-OIME-4-ISOPRYL-TETRA 0 1753 8013 7: UNDECANOL 0 1765 7987 8: ACETAMIDE,N-ALLYL- 0 747 7892 9: PYRAN-2-ONE(3H), 5,6-DIHYDRO-4-ISOPROPYL 0 1672 7792 10: OCTADECANOL 0 1818 7695 Scan 3854 C64.64B 100"( ~' II ~ fi9 129 dil. di. I . m1n) Df DRTR:ERKER08R.0 16` 213 a57 , . I , ~ . I. 9~ . 817B1 GERRNIOL, k1771 NONYL k1721 BUTRNONE-2, 3,3-OIHETHYL-4-HYOROXY- 100 1 71 r100 ~JII i~l~ B II000~ 100 ~0 501 0 ,_ 50 100 TETRRHYOR0- RLCOHDL 150 200 HassiCharpe 50 250 300 T: nul). Z: Scan 3739 (63.169 min) of GRAPH)CSCO Y: T1C of DRTA:EAKEAD3A.D [MS2] X: Set of 4 MS Scan 3854 (64.648 min) of DATA:EAKEA03A.D LIGHTS (CONC.) m/z abu nd. m/z abund. m/z abund. m/ z abund. 28.10 14 60.00 21 87.10 8 139. 20 3 29.10 46 61.00 I5 95.10 8 157. 10 5 31.10 3 67.10 10 97.10 13 171. 10 6 39.10 14 68.10 6 98.10 6 185. 10 11 41.10 87 69.10 25 99.10 3 199. 20 3 42.20 17 70.10 11 101.00 10 213. 25 10 43.10 83 71.10 21 109.10 3 227. 25 5 44.10 4 73.10 24 111.20 10 239. 35 25 45.20 4 74.00 5 112.20 3 240. 35 5 53.10 6 81.10 7 115.10 6 256. 45 14
Page 197: nbi31d00
LIBRARY SEARCH RESULTS Scan 3329 (57.902 min) of DATA:EAKEA03A.D LIGHTS (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS 1: OCTADECANOL 2: UNDECANDL 3: GERANIOL, TETRAHYDRO- 4: GERANIOL, TETRAHYDRO- 5: CYCLOHEXANONE, 4-HYDROXY-2,2,6-TRIMETHYL 6: NONYL ALCOHOL 7: FURANONE-2-(3H)-,3-HYDROXYMe-5-METHYL- 8: OLEIC ACID, METHYL ESTER 9: FURANONE-2(3H), 4- ISOPROPYL- 10: CYCLOHEXANE-1,4-DIOL, 2,2,6-TRIMETHYL- Scan 9329 C57.902 mfn) 100 _ I11 159 o. I~) YI, la !, , i [ of ORTRc CAS II Library Match Index II Quality 0 1818 9474 0 1765 9286 0 1795 8833 0 1781 8612 0 1717 8590 0 1771 8375 0 716 8116 0 1736 7862 0 1787 7835 0 1710 7574 ERKER08R.0 8(d8 ~ 100 '.0 0181E OCTROECRNOL ~ 100~1 113 1I I f9 ~ ~ i r100 m ~ M1765 UNOECRNGL ~ 100~ r r100 `0a a ~ ~B I 100 50 a 01795 GERANIOL. TETRRHYDRO- ..~^-.. 6 70 50 100 Fk100 E50 150 Z00 250 80 k0 Mass/CharBe GRRPHICSCO [62] T: null. Z: Scan 3306 (57.604 min) of Y: TIC of DRTA:EAKEA03R.D X: Set of 4 MS Scan 3329 (57,902 min) of DATA:EAKEA03A.D 1131D LIGHTS (CONC m/z .) ab und. m/z abund. m/z abund. m/ z abund. 28.10 26 55.10 100 79.00 7 98. 10 11 29.10 35 56.10 35 80.10 9 105. 20 8 32.10 8 57.10 61 81.10 16 110. 20 7 39.10 18 67.10 20 82.10 18 111. 20 27 41.10 89 68.10 14 83.10 42 112. 20 8 42.20 25 69.10 54 84.10 15 125. 20 18 43.20 88 70.10 67 85.10 16 139. 20 8 51.10 7 71.10 41 96.10 11 159. 10 19 53.00 16 78.00 6 97.10 42 308. 45 10 54.10 32
Page 198: nbi31d00
LIBRARY SEARCH RESULTS Scan 2721 (50.077 min) of DATA:EAKEA03A.D LIGHTS (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS II 1: OCTADECANOL 0 2: UNDECANOL 0 3: OCTEN-2-AL,2-PROPYL- 0 4: OLEIC ACID, METHYL ESTER 0 5: CYCL.OHEXANONE, 4-HYDROXY-2,2,6-TRIMETHYL 0 6: GERANIOL, TETRAHYDRO- 0 7: CYCLOHEXANONE,2,3-EPOXY-3,5,5-TRIMETHYL- 0 8: NONYL ALCOHOL 0 9: OCT-3-EN-2-ONE 0 10: GERANIOL, TETRAHYDRO- 0 Scan 2721 (50.077 29 III ~ Ji ~6 ~7 1 m1n) of ORTR:ERKER0SR.0 125 280 OCTROECRNOL Library Match Index II Quality 1818 9422 1765 8781 1452 8483 1736 8277 1717 8213 1795 7953 1526 7918 1771 7840 1569 7799 1781 7637 1Flp, \ r101a y~ a 0 13 II 193 I r. m a k1785 UNDECRNOL ; 1©e rl ~~ 83 n s I ~ 11 61 81452 OCTEN-2-RL.2-PROPYL- 100 100 I ' ~ ~ - 50 ?~ 9 I I 5 L I 125 I3 I 50 0 l ~ ' i -r r r r r ~ 0 50 100 150 200 25 0 _ MassiCharp® T: nu11. Z: Scan 241D (41.974 min) of GRAPHICSCO Y: TIC of DATA:EAKER03A.D [MS2] X: Set of 4 MS Scan 2721 (50.077 min) of DATA:EAKEA03A.D LIGHTS (CONC m/z .) abund . m/z abund. m/z abund. m/ z abund. 28.10 2 1 55.10 100 82.10 17 110. 20 9 07 29.10 3 9 56.10 32 83.10 50 111. 20 37 r 29 80 7 57 10 46 84 20 20 112 20 12 w . 39.10 1 9 . 67.10 18 . 85.10 . 20 125. 20 20 m C0 41.10 9 7 68.10 14 95.10 7 139. 20 8 -1 42.20 2 9 69.10 49 96.10 13 159. 10 14 m un 19~ 43.10 8 1 70.10 31 97.10 53 160. 00 9 53.10 1 2 71.10 25 98.10 14 280. 35 18 54.10 2 9 81.10 13
Page 199: nbi31d00
LIBRARY SEARCH RESULTS Scan 3333 (57.955 min) of DATA:EAKER03A.D LIGHTS (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CA9 # Library Match 1: OCTADECANOL 2: UNDECANOL 3: CYCLOHEXANONE, 4-HYDROXY-2,2,6-TRIMETHYL 4: GERANIOL, TETRAHYDRO- 5: GERANIOL, TETRAHYDRO- G: FURANONE-2-(3H)-,3-HYDROXYMe-5-METHYL- Index # Quality 0 1818 9152 0 1765 9036 0 1717 8688 0 1781 8584 0 179S 8560 0 716 8185 7: NONYL ALCOHOL 0 1771 8154 g: CYCLOHEXANE-1,2-DIOL,I,3,3-TRIMETHYL- 0 1629 7711 9: FURANONE-2(3H), 4- ISOPROPYL- 0 1787 7650 10: HEPTANAL 0 1433 7621 Scan 3333 (57.955 mtn) of DRTR:ERKERID3R.0 r106 159 30B ~ 13 ~' 1R 3 k181B OCTRDECRNOL I/ I ~ ~9 F10B ~yJ 1 u I 1 `0 C N '6 k1765 IJNOECRNOL ¢ r106 * 17 17 CYCLOHEXRNPNE. 4-HYOROXY-2,E.E-TRIMETHYL RI ~' 1R O ~J • ~ pI 1 3 ~ F EEE1 L 111 1 r i 50 1m0 15p 200 250 300 Mass/Charpe T: null. Z: Scan 3329 (57.902 min) of GP,RPHICSCD Y: TIC of DRTR:ERKERD3R.D [MS21 X: Set of 4 MS Scan 3333 (57.955 min) of DATA:EAKEA03A.D LIGHTS (CONC m/z .) abun d. m/z abund. m/z abund. m/ z 28.10 19 54.10 25 79.10 8 99. 10 29.10 38 55.10 100 81.10 13 106. 10 39.10 20 56.10 30 82.10 18 110. 20 41.10 91 57.10 53 83.10 47 111. 20 42.20 23 67.10 22 84.10 19 125. 20 43.10 85 68.10 12 85.10 17 139. 20 44.20 7 69.10 50 95.10 8 153. 20 51.10 10 70.10 74 96.10 11 159. 10 52.10 7 71.10 47 97.10 40 308. 45 53.10 13 78.10 8 98.20 12 abund. 7 7 7 26 16 8 8 19 8
Page 200: nbi31d00
LIBRARY SEARCH RESULTS Scan 3355 (58.239 min) of DATA:EAKEA03A.D LIGHTS (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS t Library Index 7t Match Quality 1: OCTADECANOL 0 1818 9579 2: UNDECANOL 0 1765 8823 3: CYCLOHEXANONE, 4-HYDROXY-2,2,6-TRIMETHYL 0 1717 8471 4: GERANIOL, TETRAHYDRO- 0 1795 8196 5: OCTEN-2-AL,2-PROPYL- 0 1452 8048 6: HEPT-3-EN-2-ONE,S-ISOPROPYL- (SR131C) 0 1528 8020 7: TRIDECANAL 0 1478 7985 8: HEPTANONE-2, 5-ISOPROPYL-7,4-OXIDE-(BU-2 0 1748 7956 9: GERANIOL, TETRAHYORO- 0 1781 7946 10: OLEIC ACID, METHYL ESTER 0 1736 7849 5can 3355 (5B,239 mtn) o£ 0RTR:ERKER09R.0 SRO 97 11 1 123 159 ~1013 ~ 43 ~ I IIBg ~~.,~ilu .~~,. . ,1, , .1 m 61B16 OCTRGECRNOL IO 1 97 111 r1®0 ~ c RJ 431 1 4 I, 69 I I I a '~ k1765 IJNCECRNOL 1R 160 3 1 97 r ¢ 0J 1 ~ l ff _ IP1717 CYCLOHEXRNt7NE. 4-HYOROXY-2.2,6-TRIMETHYL IBD ~, BB F100 56~ 7 I B ~ I I I u 1 41] B0 i i ~ r B0 100 120 14® Mass/CharBa T: null. Z: Scan 3333 (57,955 min) of GRRPHICSCD Y: TIC of DATR:ERKERD3A.D [MS23 X: Set of 4 MS Scan 3355 (58.239 min) of DATA:EAKEA03A.D LIGHTS (CONC, m/z a ) bund. m/z abund. m/z abund. m/ z abund. 28.20 17 54.00 23 79.00 7 99. 10 5 29.10 37 55.10 80 81.10 12 105. 10 5 30.10 4 56.10 34 82.10 18 110. 20 6 39.10 20 57.10 67 83.10 40 111. 20 29 41.10 84 67.10 15 84.10 13 112. 10 8 42.20 25 68.10 14 85.10 16 118. 10 4 43.10 100 69.10 53 95.10 6 124. 20 6 44.10 5 70.10 26 96.20 11 125. 20 18 51.10 6 71.10 28 97.10 41 139. 20 9 53.00 11 78.10 5 98.10 9 159. 00 14
Page 201: nbi31d00
LIBRARY SEARCH RESULTS Scan 3477 (59.805 min) of DATA:ERKEA03A.D LIGHTS (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: TETRADECANE 0 1846 9317 2: 3-HEXANONE 0 469 9160 3: HYDROCARBON 0 32 9034 4: TRIDECANAL 0 1478 8407 5: 1,3-DIOXOLAN-2-ONE,4-METHYL- 0 730 8054 6: PYRAN-2-ONE,3,4,5,6-TETRAHYDRO-4-OH- 0 709 8031 7: PYRROLIDIN-2-CARBOXALDEHYDE 0 1474 8004 8: CYCLOHEXANE-1,2-DIOL, I-METHYL- 0 1716 8002 9: FURANONE-2-(3H)-,3-HYOROXYMe-S-METHYL- 0 716 7925 10: FURANONE-2(3H), 4,5-HYDRO-3,3-OIME-4-HO- 0 1647 7806 Scan 3477 (59.605 100 ~.. 01~ . , I 3 71,i'l i l 3 l .{p7 , Ik164s iI 71 ( m1n) Df ORTR:ERKER03R.0 99 127 14 1 171 ~100 .,.. . ,.. . . . ~ TETRROECRNE 0469 3-HEXRNONE 71 100 #32 HYOROCRRBON 100~ _ 113 100 5 '\ ~ tl ~ q3 7 I 71 I 9 i 9 0 I I ~ 40 60 80 100 120 140 160 MassiCharge _. GRAPHICSCD [MS2I T: null. Z: Scan 3355 (58.239 min) of Y: TIC of DATA:ERKERD3R.D X: Set of 4 MS Scan 3477 (59.805 min) of DATA:EAKEA03A.D ,y//c ~' t~7 a4r.-.9' C2 2 LIGHTS (CONC.) m/z abu nd. m/z abund. m/z abund. m/ z abund. ut ~ 28.20 7 55.10 41 82.00 5 112. 20 6 w m °D 29.10 22 56.10 20 83.10 15 113. 20 8 m 32.10 6 57.10 96 84.10 9 125. 20 5 0 39.00 7 58.10 6 85.10 33 127. 20 9 ~ 41.10 51 67.10 5 96.20 4 135. 10 6 43.20 100 68.10 6 97.10 12 141. 20 8 44.00 5 69.10 21 98.20 5 155. 20 6 51.20 4 70.10 20 99.10 12 169. 10 5 53.10 4 71.10 64 107.10 5 171. 10 14 54.10 8 72.10 4 111.20 8 172. 10 9
Page 202: nbi31d00
LIBRARY SEARCH RESULTS Scan 3222 (56,500 min) of DATA:EAKEA03A.D LIGHTS (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index S Quality 1: MYOSMINE 0 10 9776 2: PYRROLE[1,2a]PYRAZINE,3,6-DIMETHYL- 0 1371 7377 3: BENZONITRILE,2-AMINO- 0 1488 7070 4: COUMARIN 0 1861 6996 5: BENZIMIDAZOLE 0 95 6771 6: PYRIOINE,2-(1-PROPENYL)- (SBB 23601 0 543 6730 7: NORNICTINE,1-NITROSO- 0 1013 6686 8: TETRALONE-1 0 834 6649 9: BENZIMIDAZOLE 0 614 6601 10: IMIDAZO[1,2a]PYRIDINE 0 968 6601 Scan 3222 (56.300 m1n) of DRTRcERKER03R.0 41 51 76 _ 91 100 16 146 ~~ i., .~Lli... .J~...... ,~i~i.......,~A. .....,,~. . .,I. ,. ,. 0/C M10 MYOSMINE ` _1--- 51 76 10,5 i I 1 11 16 146 II k1371 PYRROLEC1.2a]PYRRZINE,3,6-OII1ETHYL- 99 51 104 118 100 II N1466 6EN20NITRILE,E-RMINO- 1003 63 64 100 50~ \ / jl 16 ~S0 0 444--------- \ ~ EEn 0 20 40 60 80 160 1E0 142 . Mass/Charpe T: null. Z: Scan 2721 (50.D77 min) of GRAPH]CSCO Y: TIC of DRTR:ERKER03R.D [MS21 X: Set of 4 MS Scan 3222 (56.500 min) of DATA:EAKEA03A.D LIGHTS (CONC,) m/z abu nd. m/z abund. m/z abund. m/ z ebund. 28.10 15 51.10 26 69.10 1 91. 00 11 ut N w 29.10 1 52.00 8 71.10 1 92. 00 3 ~ po 30.20 1 53.00 2 72.00 1 97. 10 1 J 37.10 4 54.10 1 74.00 2 103. 20 2 m 38.10 39.10 10 24 55.10 66.10 2 1 75.00 76.00 4 104. 7 105. 10 10 10 20 E" ul 40.10 9 57.10 2 77.10 12 106. 10 2 41.10 26 58.50 2 78.00 24 118. 10 100 42.10 17 61.00 3 79.00 3 119. 10 9 43.10 2 62.00 7 84.10 1 120. 10 1
Page 203: nbi31d00
LIBRARY SEARCH RESULTS Scan 1313 (23.8fi8 min) of DATA:EAKEA03A.D LIGHTS (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: UNDECANOL 0 1765 9791 2: OCTADECANOL 0 1818 9646 3: GERANIOL, TETRAHYDRO- 0 1795 9522 4; GERANIOL, TETRAHYDRO- 0 1781 9323 5: NONYL ALCOHOL 0 1771 9229 6: CYCLOHEXANONE, 4-HYDROXY-2,2,6-TRIMETHYL 0 1717 8667 7: PYRAN-2-ONE(3H),4-ISOPROYL-6-ME-5,6-HYDR 0 1671 8507 8: OCTANOL-1 0 1546 8395 9: PYRAN-Z-ONE(2H),6,6-DIME-4-ISOPRYL-TETRA 0 1753 8320 10: FURANONE-2(3H), 4- ISDPROPYL- 0 1787 8269 Scan 1313 (.23.B66 m1n) of DRTR:ERKER03R.D 100 29 ~, ~~5 pp 1 63 97 r100 0~I I ~41 ,f1i~ Illrl I~I. `I ~ v u m v 01765 t1N12ECRNOL 11JJ f~1 B 3 97 k1B1B OCTRDECRNOL ~ 100 97 r100 J"'L..000~ l ^ d C 0J I 3 l~l 'li l3 ~ . 61795 GERRNIOL. TETRRHYDRO- 15~~T BI4 97 100 90 4050 II{~.,60 70 60 90 `,100 110 _ Mass/CharBa T: null. T: Scan 1154 (21.833 min) of GRAPHICSCO Ya TIC of DATA:EAKEA83A.D IMS27 X1 Set of 4 MS Scan 1313 (23.868 min) of DATA:EAKEA03A.D LIGHTS m/z (CONC.) abu nd. m/z a bu nd. m/z abund. m/ z abund. 28.1 0 18 53.00 10 68.10 16 84. 10 18 29.1 0 42 54.10 17 69.10 47 85. 20 9 ut N 39.1 0 34 55.10 64 70.10 33 97. 10 23 w 41.1 0 100 56.10 42 71.10 20 98. 20 8 a OD 42.1 0 21 57.10 39 82.10 13 111. 20 12 J B ~ 43.1 0 64 67.10 16 83.10 37 N
Page 204: nbi31d00
LIBRARY SEARCH RESULTS Scan 3566 (60.947 min) of DATA:EAKEA03A.D LIGHTS (CONC.) Library file; DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # 1: BETA-NICOTYRINE 0 2: QUINOXALINE,DIMETHYL- (SBB 174) 0 3: PYRIDINE,2-(N-METHYLPYRROL-2-YL) 0 4: PYRIDINE,3-(2-METHYL-I-PYRROLYL)- 0 5: UNKNOWN (NICOTINE LIKE) (SWW 206D) 0 6: QUINOXALINE,2-ETHYL- 0 7: PYRROLE,N-(2-PYRIDYLMETHYL)- 0 8: INDOLE,1,2,3-TRIMETHYL- 0 9: QUINOLINE,DIMETHYL (SBB 173D) 0 10: QUINOLINE,2,8-DIMETHYL- (SBB 230D) 0 Scan 3566 C60.947 m1n) inn, of DRTReERKER03R.D 116 130 k536 BETR-NICDTYRINE 42 79 @0 117 136 / / / / / i I u n I Library Match Index >k Quality 536 9540 609 9397 291 9177 1011 8337 349 8311 1125 7641 1590 7634 1068 5926 559 5795 561 5480 ,,-l r100 1513 1 Iial M609 QLJINOxRLINE,DIMETHYL- (5B6 174) 100, 39 65 78 l 130 ~ a,f se 1 1003 50~ 0 r100 ~ I k291 PYRIDINE.R-(N-FIETHYLPYRROL-£-YL) 65 130 r 39 ~ 79 ` Z: Scan 3477 (59.805 min) of 40 60 80 100 1713 1413 ' MarsiCharge T: null. CRAPHICSCD Y: TIC of DRTA:ERKER03A.D [MS2I X; Set of 4 MS Scan 3566 (60.947 min) of DATA:EAKEA03A.D O/ \ LIGHTS (CONC.) m/z ab und. m/z abund. tn/z abund. m/ z abund. 28.10 15 55.10 6 78.10 14 116. 20 3 29.10 3 56.20 2 79.10 7 116. 10 12 37.10 3 57.10 3 80.10 5 117. 10 10 38.10 5 61.10 3 85.10 2 118. 10 3 39.10 15 62.00 8 86.00 2 128. 10 4 40.20 3 63.00 17 87.10 3 130. 10 32 41.10 8 64.00 6 88.00 3 131. 10 7 42.10 18 65.00 4 89.00 12 133. 10 2 43.10 5 67.00 2 90.00 9 142. 20 5 49.20 2 70.10 2 91.00 2 143. 10 6 0 4 e ti~ 7B 89 ~..ih~ ....ii. / 100 ' 15 B 30
Page 205: nbi31d00
45.10 14 70.10 52 106.10 15 LIBRARY SEARCH RESULTS Scan 6106 (93.559 min) of DATA:EAKEA03A.D LIGHT5 (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Libra Index ry Match # Quality 1: NORN ICOTINE,N-FORMYL- 0 761 9692 2: N-FO RMYL NORNICOTINE 0 13 9505 3: BIPR IDINE-2,3'-6-DNE,3,4,5 ,6-TETRAHYDRO- 0 966 8666 4: NORN ICOTINE,N-BUTYRYL- (SWW 84D) 0 337 7055 5: NORN ICOTINE,N-ACETYL- 0 760 6973 6: N-AC ETYL NORNICOTINE 0 18 6914 7: NORN ICOTINE 0 1016 6695 8: 5H-C YCLOPENTAPYRAZINE,6,7- HYDRO-2-ETHYL- 0 690 6629 9: NORN ICOTINE,N-BUTYRYL- 0 1598 6623 10: BENZ OXAZOLE,C3-ALKYL- (SB6 153D) 0 618 5604 6can 6106 (93.559 m/n) Df ORTR:ERKERg3R.0 1©6 ,~ _ 76 1_05 11B0 ~i7 176 ~ k761 NQRNICQTINE,N-FQRMYL- 0
Page 206: nbi31d00
m 44.10 2 68.10 6 94.10 1 146.20 1 45.20 1 69.10 8 98.10 100 147.20 8 50.10 9 70.10 7 99.10 6 148.10 2 51.10 16 71.10 1 104.10 4 161.00 1 52.10 8 73.10 1 105.10 3 175.10 11 53.00 3 74.00 1 106.10 3 176.10 34 54.00 2 75.00 1 118.20 1 177.10 4
Page 207: nbi31d00
~~ .-Ta-51.10 52.10 53.10 54.10 17 6 5 4 B0 74.00 75.00 76.10 77.10 4 4 6 10 LIBRARY SEARCH RESULTS Scan 3739 (63.169 min) of DATA:EAKEA03A.D LIGHTS (CONC.) 103.10 104.10 105.10 106.10 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS 7 8 6 6 156.10 157.10 158.10 159.10 CAS # Library Index # 1: HYDROCARBON 2: TETRADECANE 3: 3-HEXANONE 4: TRIDECANAL 5: PYRROLIOIN-2-CARBOXALDEHYOE 6: 1,3-DIOXOLAN-2-ONE,4-METHYL- 7: PYRAN-2-ONE,3,4,5,6-TETRAHYDRO-4-OH- 8: SUGAR DIANHYDRIDE (SR 1770) 9: PENTADECANAL 10: FURANONE-2(3H), 4,5-HYDRO-3,3-DIME-4-HO- Sc an 10 0 3 m IN ] 4f3 c m a c 3 0 ~~ ¢ 0J~ 3 100 GRAPHICSCO [MS2] S 3 65 99 127 ~1,,.41 169 632 HYDR0CRR60N 111646 TETRRDECRNE k469 3-HEXRNONE 100 ~tt,,, FE 117 I 82 J00 ~50 60 60 100 120 140 160 1812 NassiChar9e T: null. I: Scan 3566 (60.947 min) of Y: TIC of DRTA:ERKEAD3R.D X: Sai of 4 MS Scan 3739 (63.169 min) of DATA:EAKEA03A.D 9 59 100 12 Match Quality 9393 9281 9170 8339 8241 8194 8146 7752 7729 7698 /Ja.~ // C CG J LIGHTS (CONC.) m/z abu nd. m/z abund. m/z abund. m/z ebund. 28.10 7 56.20 19 82.10 5 113.20 11 N w B 29.10 22 57.10 100 83.10 12 125.20 4 W 32.10 3 58.10 6 84.20 8 127,20 9 J 0 39.10 7 67.10 6 85.10 41 140.20 4 m 41.10 48 68.20 5 97.10 11 141.20 8 w 42.20 20 69.10 18 98.20 5 155.10 6 43.20 100 70.20 14 99.10 15 169.20 5 44.20 4 71.10 60 111.20 7 183.20 4 55.10 39 81.00 3 112.20 6 (63.169 mi n) oF DRTR:ERKER03R.O 32 1846 469 1478 1474 730 709 867 1454 1647
Page 208: nbi31d00
AF4*rf A p.z 10 Ml:tir44 ~t akG, I
Page 209: nbi31d00
55.10 62 82.10 7 115.20 5 285.35 53 56.10 100 83.10 22 116.10 10 286.35 11 57.10 70 84.10 8 117.10 9 340.45 18 58.00 6 85.10 11 125.20 5 341.45 5 LIBRARY SEARCH RESULTS Scan 4776 (76.490 min) of DATA:EAKEA03A.D LIGHTS (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: NICOTINAMIDE,N-METHYL (SWW27D) 0 250 9217 2: PYRIDINE,3-PROPIONYL- 0 476 8721 3: PYRIDINE,4-PRDPIONYL- 0 1613 8055 4: 3-ACETYLPYRIDINE 0 38 7362 5: NICOTINAMIDE 0 759 6929 6: PYRIDINE,3-BUTYRYL 0 306 6909 7: PYRIDINE,4-ACETYL- 0 475 6871 8: BENZOXAZOLE,2,4-DIMETHYL- 0 1185 6569 9: 3-PYRIDINECARBOXALDEHYDE (NICOTINALDEHYD 0 173 6472 10: KETONE,CYCLOPROPYL-3-PYRIDYL (SWW 116D) 0 297 6192 100 0 .,./ .. B 10 S .-~ ~~ 106 ( 135 I k^c50 NICOTINRMIDE.N-METHYL C5WN27D) 100 51 ~ -~I00 , I B I 108 13S ll 0 Scan 4776 (76.490 m1n) of ORTR:ERKER03R.D 26 70 I ... ......... 0478 PYRIOINE.3-PROPIONYL- 40 13S ~100 ~ Ili Ig I~ 106 ~ ~Ln 100 50 0 t8 i M1B13 PYRIOINE,4-PROPIONYL- S1 7_8 ~ 13S Fk100 ~I I L 106 0 FFe 40 60 60 100 120 _ Mats/Charge T: null. Z: Scan 4368 (71.256 min) of GRAPHICSCD Y: TIC of DRTR:ERKER03R.D IMS2) X: Set of 4 MS Scan 4776 (76.490 min) of DATA:EAKEA03A.D LIGHTS (CONC.) m/z abund. m/z abund. m/z abund. m/ z abund. 28.10 24 43.10 5 54.10 3 77. 10 21 29.10 9 44.20 4 55.10 4 78. 00 100 30.10 6 45.10 9 57.10 4 79. 10 10 32.00 3 48.10 2 58.00 11 105. 10 19 37.00 5 49.10 12 67.10 3 106. 10 61 38.10 7 50.10 45 69.10 3 107. 10 6 39.10 8 51.10 71 70.10 3 123. 10 30 40.10 4 52.00 22 75.00 6 135. 10 65 41.10 8 53.00 12 76.10 7 136. 10 25 42.20 3
Page 210: nbi31d00
56.10 100 83.10 18 117.20 7 258.25 11 57.10 58 84.10 7 125.20 5 269.35 4 58,10 4 85.10 10 129.10 19 312.35 13 LIBRARY SEARCH RESULTS Scan 3881 (64.997 min) of DATA:EAKEA03A.D LIGHTS (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: OCTADECANOL 0 1818 9268 2: CYCLOHEXANONE, 4-HYDROXY-2,2,6-TRIMETHYL 0 1717 8563 3: UNDECANOL 0 1765 8437 4: TRIDECANAL 0 1478 8052 5: GERANIOL, TETRAHYDRO- 0 1795 7827 6: PHYTOL 0 55 7794 7: GERANIOL, TETRAHYDRO- 0 1781 7789 8: OCTEN-2-AL,2-PROPYL- 0 1452 7687 9: TETRADECANE 0 1846 76S0 10: 3-HEXANONE 0 469 7632 9can 3861 (64.997 mIn) of DRTR:ERKER08R.0 / ~ ~„ 111 125 139 (100 1001 d' 011 43i11 . iln7 1 B3 .31 4 k1616 OCTRDECRNOL _ 111 dX B3 '7p F~ I 01717 jj,,CYCLOHEXRNONE, 4-HYOROXY-2,2,6-TRIMETHYL IO~J I1 I~7 lll 1I 1 3 r100 617E5 l1NDECRNOL 69 63 100 . y rd 40 60 60 100 120 140 MassiCharpe T: null. Z: Scan 3854 (64.648 min) of GRRPHICSCO Y: TIC of DRTR:ERKER03R.D [MS27 X: Set of 4 MS Scan 3881 (64.997 min) of DATA:EAKEA03A.D LIGHTS (CONC. ) m/z a bund. m/z abund. m/z abund. m/ z abund. Ln r 28.20 8 5 4.00 12 71.10 36 97. 10 47 w m aD 29.10 26 5 5.10 80 81.10 13 98. 10 13 ~ 39.20 II 5 6.00 40 82.10 19 110. 30 5 m 40.20 9 5 7.10 81 83.10 55 111. 20 27 U'l 41.10 62 8 7.10 19 84.10 18 125. 20 19 42.20 25 6 8.10 15 85.10 19 139. 20 10 43.10 100 6 9.10 S1 95.00 9 153. 20 8 44.00 9 7 0.10 30 96.10 14
Page 211: nbi31d00
44 , IV) I IIS.YIY/ i,# . _..DII:~YlW 44.70 1 66.00 2 87.00 1 143.20 1 45.50 1 67.10 2 88.10 1 145.10 57 50.10 16 68.10 3 89.00 5 146.10 65 51.10 25 69.10 1 90.10 5 147.10 7 52.10 8 71.10 1 91.10 11
Page 212: nbi31d00
LIBRARY SEARCH RESULTS Scan 3994 (66.451 min) of DATA:EAKEA03A.D LIGHTS (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: HYDROCARBON 0 32 928S 2: TETRADECANE 0 1846 9232 3: 3-HEXANONE 0 469 9166 4: TRIDECANAL 0 1478 8342 5: PYRROLIDIN-2-CARBOXALDEHYDE 0 1474 8175 6: 1,3-DIOXOLAN-2-ONE,4-METHYL- 0 730 8098 7: PYRAN-2-ONE,3,4,5,6-TETRAHYDRO-4-OH- 0 709 8057 8: FURANONE-2(3H), 4,5-HYDRO-3,3-OIME-4-HO- 0 1647 7760 9: CYCLOHEXANONE, 4-HYDROXY-2,2,6-TRIMETHYL 0 1717 7754 10: PHYTOL 0 55 7691 4can 3994 (66.451 m1n) of ORTR:ERKER08R.0 N 65 113 127 1 9 3 II, 57,.LI. J. 355 7 1532 HYOROCRRBON ,~A ~ d 113 12) r100 13 ~ S~ II l5 il i I1,0~ fl3 II~5? iI IF1646 TETRRDECRNE B~5 I k469 3-HEXRNONE 11a0 .` 100 100 501 3 I 57 1 ~ 150 R3 II ~I J I ~ ~ !:0 ISO 160 Tc null. Z: Scan 3948 (65.858 mio) of 40 60 BB 100 120 140 MassiCharga GRRPHICSCO Y: TIC of DRTR:ERKERD3R.D [M>21 X: Set of 4 MS Scan 3994 (66.451 min) of DATA:EAKEA03A.D cZy ,l/C, LIGHTS (CONC.) m/z abu nd. m/z abund. m/z abund. m/ z abund. 28.10 9 57.10 98 83.10 16 113. 20 11 29.10 19 58.10 6 84.20 9 125. 20 4 31.90 4 67.10 7 85.10 39 126. 10 5 39.10 6 68.20 5 86.10 4 127. 20 11 41.10 49 69.10 24 97.10 11 141. 20 7 42.20 19 70.10 14 98.20 7 155. 20 7 43.10 100 71.10 63 99.10 14 168. 20 4 44.20 5 72.10 3 111.20 8 169. 20 4 55.10 37 82.20 6 112.20 5 197. 20 4 56.10 22 160 r
Page 213: nbi31d00
55.10 39 81.10 LIBRARY SEARCH RESULTS Scan 4368 (71.256 min) of DRTA:EAKEA03A.D LIGHTS (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: GERANIOL, TETRAHYDRO- 0 1781 8356 2: BUTANONE-2, 3,3-DIMETHYL-4-HYDROXY- 0 1721 8236 3: GERANIOL, TETRAHYORO- 0 1795 8236 4: HEXANAL 0 1438 8215 5: ACETAMIDE,N-ALLYL- 0 747 8203 6: NONYL ALCOHOL 0 1771 8185 7: UNDECANOL 0 1765 7933 8: SUGAR DIANHYDRIDE (SR 1840) 0 869 7899 9: PYRAN-2-ONE(2H),6,6-DIME-4-ISOPRYL-TETRA 0 1753 7861 10: ACETAMIDE,N-(2-PROPENYL)- 0 1321 7706 Scan 4366 (71.256 100 73 129 I I k17tE1 10~~11 IIII ~6 I GRAPH]CSC:O [MS21 f T: null. Z: Scan 4035 (66.978 min) of Y: TIC of DATA:EAKEA03A,D X: Set of 4 MS Scan 4368 (71.256 min) of DATA:EAKEA03A.D LIGHTS (CONC.) m/z abu nd, m/z abund. m/z abund. m/ z abund. 28.20 12 60.00 27 87.00 7 129. 20 23 u+ r w 29.10 42 61.00 17 95.10 7 143. 20 6 m 30.20 3 67.10 9 96.10 . 5 171. 10 6 Co 31.20 4 68.10 6 97,10 18 185. 10 17 a m 39.20 11 69.10 29 98.10 8 199. 20 5 m ~ 41.10 80 70.10 12 99.10 4 227. 25 6 42.20 21 71.10 25 101.10 9 241. 35 15 43.10 82 73.00 32 109.10 4 255. 35 3 44.20 5 74.10 4 110.20 3 267. 25 29 45.10 5 79.00 4 111.20 10 268. 25 5 min) of ORTR:ERKER03R.0 185 241 ~ 340 rf00 . I I , i. I, 'I,B 5 tlddl`~` IP17B1 GERANIOL. TETRRHYORO- 83 / 1 BUTRNONE-2. 3.3-OIM6THYL-4-HYDRDXY- k1795 GERRNIOL, TETRRHYDRO- / 100 Z00 300 Masa/Chargr
Page 214: nbi31d00
LIBRARY SEARCH RESULTS Scan 3948 (65.858 Nin) of DATA:EAKEA03A.D LIGHTS (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS it Library Index lk Match Quality 1: BENZOPHENONE 0 1798 9931 2: PROPIOPHENONE 0 176 8793 3: BENZOIC ACID, METYL ESTER 0 1544 8777 4: BENZIL 0 802 8760 5: BENZOIC ACID, ETHYL ESTER 0 1543 8629 6: ACETOPHENONE 0 440 847B 7: PHTHALIDE 0 1841 8422 8: PHTHALIDE 0 54 8286 9: BENZYALDEHYDE 0 57 7847 10: BENZAMIDE 0 181 7729 Scan 3946 C65.65 8 m1n) of ORTR:ERKER03R.0 100' 100 ~ 50 1 51 L77 ~ 1 05 126 152 182 ~ . .. . ..,. ... . . . 01798 BENZOPHENONE 100, ~'100 50 ~` ~ 7 1 2 m "-~I 51 7 1 05 ~ 182 I U c m 0 i n c N176 PROPIOPHENONE 3 100 50 51 134 r100 Q J [ 77 f~05 ~ 0 81544 BENZOIC RC ID. METYL ESTER 1003 50 51 I ~ ' { 13 6 100 50~ ~ Y1 77 ' 11 1I ~ ` ~05 ~~~ 50 d 111 ~~~ JJJ ~ I -- - ... ttt 0 ~ ~ r ^ r ^~ r^ la 413 60 80 100 120 140 160 160 MarsiCharga GRRPHICSCD (MS21 T: null. Z: Scan 3881 (64.997 min) of Y: TIC of DATA:EAKERD3A.D X: Set of 4 MS Scan 3948 (65.858 Nin) of DATA:EAKEA03A.D LIGHTS m/z (CONC.) abun d. N/z abund. N/z abund. m/ z abund. 28.1 0 3 5 2.00 3 73.10 1 107. 10 1 29.1 0 3 5 3.00 2 74.00 7 126. 10 2 32.2 0 2 5 5.10 3 75.10 5 151. 10 2 38.1 0 2 5 6.10 2 77.00 77 152. 10 4 39.1 0 5 5 7.10 2 78.10 6 153. 10 3 41.1 0 3 6 2.00 2 83.10 2 154. 10 2 42.2 0 1 6 3.10 3 85.10 2 181. 10 11 43.2 0 4 6 9.10 2 97.10 2 182. 10 59 50.1 0 18 7 0.10 2 105.10 100 183. 10 9 51.1 0 50 7 1.10 2 106.10 8
Page 215: nbi31d00
LIBRARY SEARCH RESULTS Scan 4035 (66,978 min) of OATA:EAKEA03A.D LIGHTS (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS GAS # Library Match Index # Quality 1: HEPT-3-EN-2-ONE,S-ISOPROPYL- (SR131C) 0 1528 9011 2: HEPTANDNE-2., 5-ISOPROPYL-7,4-OXIDE-(BV-2 0 1748 8830 3: OCTADECANOL 0 1818 8681 4: HEXANOIC ACID, 2-ISOPROPYL-5-OXO- 0 1832 8537 5: HEPT-5-EN-2-ONE, 6-METHYL 0 1836 8498 6: DIOXOLANE-1,2,2,2-DIMETHYL-4-HYDROXYME- 0 843 8291 7: 2(3H)-FURANONE,4,5-HYDRO-3-(2-OXYPROPYL) 0 685 8269 8: PENTANOIC ACID,2-METHYL-4-OXO- 0 660 8247 9: FURANONE-2(5H), 3,5,5-TRIMETHYL- 0 1757 8233 10: VALERIC ACID, 2-METHYL-4-OXO- (SWW9D) 0 241 8215 9ctar, 41335 (66.97E m1n) of ORTR:ERKER03R.q Y57 97 ig5 153 22_4 r36B k1526 HEPT-3-EN-2-0NE,5-I5DPROPYL- [BRt31G 1691 97 100 a E9 ~ 1~ 5 ~ 3 I 1 ~ L~Y N '~ k1746 HEPTRNONE-E. 5-I9PPR0PYL-7.4-0XIOE-(9V-2 r. S 1 00] 69 112 113 159 r100 n Lflp1 ~ 3 II I I ~ i~ 1 0 Ik1616 OCTROECRNOL ~_ 97 s i I 51 1 7 1 1 ~ I ~ --r 50 100 150 206 MacciCharpe T: null. Z: Scan 3994 (66.451 min) of GRAPHICSCO Y: TIC of DRTR:EAKERD3R.D [MS2] X: Set of 4 MS Scan 4035 (66.978 min) of DATA:EAKEA03A.D LIGHTS (CONC.) m/z abund . m/z abund, m/z abund. m/ z abund. 28.20 6 56.10 16 82.10 13 111. 20 15 29.20 1 7 57.10 31 83.10 25 112. 20 4 39.10 5 58.00 3 84.10 9 116. 10 2 41.10 34 61.00 24 85.10 7 124. 20 3 42.20 16 67.00 8 95.20 2 125. 20 8 43.10 100 68.10 9 96.10 7 126. 20 2 44.20 4 69.10 27 97.10 21 138. 20 2 45.00 2 70.10 14 98.10 5 139. 20 4 53.10 3 71.10 15 99.10 2 153. 20 2 54.10 8 73.10 3 110.20 5 224. 35 2
Page 216: nbi31d00
Data file: DATA:EAKEA02A.D File type: GC / MS DATA FILE Name Info: MENTHOL (CONC.) Misc Info: 3ML M+OFF 32-36,42-46 Operator : JNS Date : 21 Aug 86 12:14 pm Instrment: MS_5970 Inlet : GC Sequence index : Als bottle num : Replicate num . TIC oP ORTR:ERKERBPR.0 4. 0E6 3.BE6 2.eEE 1.OE6 10 20 30 GRRFH)CSCO [MS2.l ! n N m B %0 0 m 40 513 60 T1mm (m1n.) p m h a 70 80 9fG 16® T: null. Z: null. Y: TIC of DRTA:ERKERD2R.D X; TIC of DATA:EANEA02A.D b TI ME C of DAT NTHOL (C A:EAKEA02A ONC.) .D Pe ak.# Ret Time Ty pe Width A rea Start Time End Time 1 2 4.350 BB 0.158 54 787 452 24.181 24.737 2 5 1.991 VU 0.107 56 122 735 51.865 52.125 3 5 6.492 BB 0.203 772 771 770 56.049 57.097 r 4 5 7.608 BU 0.202 84 699 556 57.182 57.760 5 5 7.929 VV 0.152 524 12 466 57.760 58.060 ~ S 5 8.230 VV 0.147 88 452 747 58.060 58.589 '7 5 9.806 BB 0.139 52 327 696 59.490 60.031 i8. 6 0.925 BV 0.183 266 221 793 60.679 61.340 6 ~ 3:,180 BV 0.136 601 95 270 62.952 63.346 10 4.$84 BV 0.200 104 031 761 64.155 64.697 11 6 4.740 VV 0.079 285 17 101 64.697 64.868 12 6 5.839 BV 0.133 81 571 126 65.485 65.998 13 6 6.468 B8 0.133 644 38 874 66.273 66.751 14 6 6.962 BB 0.124 65 419 409 66.779 67.265 15 7 1.236 BV 0.125 565 12 218 71.008 71.374 16 7 3.363 BV 0.202 769 59 005 73.042 73.696
Page 217: nbi31d00
LIBRARY SEARCH RESULTS Scan 2867 (51.995 min) of DATA:EAKEA02A.0 MENTHOL (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS 4 Library Match Index # Quality 1: TRIACETIN 0 235 9988 2: ACETIC ACID,2-OXOPROPYL ESTER 0 727 9848 3: 2(3H)-FURANONE,2-ACETOXY-4,5-OIHYDRO- 0 674 9845 4: ACETOL 0 192 9829 5: GLYCERIN,mono-acetate 0 728 9825 6: MII-Uc 0 43 9824 7: ACETIC ACID,2-FORMYLOXY-3-HOPROP ESTER 0 717 9823 8: PYRUVALDEHYDE 0 799 9791 9: ACETIC ANHYDRIDE 0 1386 9778 10: ACETIC ACID,GLYCOLALDEHYDE ESTER 0 719 9768 Scan 2B67 (51.995 mtn) of ORTR:ERKER02R.0 r100 ~ a c n / 116 66 103 4 3 k235 TRIRCETIN / 43 6 66 103 It727 RCETIC ACID.2-OXOPROPYL ESTER B6 ~6 43 I ~ 145 k674 2(3H)-r1JRRNONE.2c-RCETOXY-4.5-1]IHYpRO- Fk_1 1313 / 72 43 ~ I / E'13 20 40 66 66 1613 120 140 Ma:m/Charpa T: null. Z: Scnn 1350 (24.350 min) of GRAPHICSCD Y: TIC of DRTA:EAKEA02A.D IMS27 X: Set of 4 MS Scan 2867 (51.995 min) of DATA:EAKEA02A.D MENTHOL (CONC.) m/z abu nd. m/z abund. m/z abund. m/ z abund. 28.10 2 43.10 100 69.10 1 115. 10 4 29.10 3 44.10 3 71.00 1 116. 10 4 ~ 30.00 1 45.10 1 73.00 2 117. 10 1 ~ 31.10 1 55.10 1 74.00 1 145. 10 10 m 32.00 1 56.00 1 85.30 1 146. 10 1 co 39.10 1 57.10 1 86.10 2 159. 10 1 J m 41.20 2 61.10 1 103.10 1 1 a'
Page 218: nbi31d00
LIBRARY SEARCH RESULTS Scan 5233 (82.383 min) of DATA:EAKEA03A.D LIGHTS (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS 1[ Library Match Index ~ Quality 1: COTININE 0 12 9765 2: N-METHYL ANABASINE (SWW 20) 0 237 9112 3: PIPERIDINE,1-ETHYL- 0 1136 8700 4: 1,5-OIMETHYL-2-PYRROLIDINONE 0 40 8625 5: NORNICOTINE,N-ETHYL- (SL 39D) 0 878 8121 6: PYRROLIDIN-2-ONE,1,5-DIMETHYL- 0 1378 8024 7: PYRIDINE,3-(I-ET-2-PYRROLIDINYL)- 0 999 7807 8: PIPERIDINE,1-METHYL- 1 1143 7287 9: PIPERIDINE,2,3-DIMETHYL- 1 1139 6759 10: 2-PIPERIDONE,6-METHYL- 0 787 6738 I ~Scan 5233 (82.383 min) of ORTR:ERKER03R.0 r100 ~ 42 51 119 147 176 I.. .ea[. ~~.,.,~~.....,i... 96~... I. . ..u.. ... ~.... . ~ i~ 42 l *12 COTININE ,ZI 119 147 176 9 6 Ai i ~ i~ 100 /kE37 N-METHYL RNRBRSINE (SWW PD) 4E 70 /11 1~ 9 1'100 ~ / 9B1 ~~ N1136 PIPERIOINE,1-ETHYL- 100-~ 100 / EE 42 99 11 6 ~'S0 0 i I ~~u 0 20 42 60 60 100 120 140 160 Mtss/Charryo T: null. Z: Scan 4776 (76.490 min) of GRRPHICSCO Y: T]C of DRTR:ERKERD3R.D [MS2] X: Set of 4 MS Scan 5233 (82.383 min) of OATA:EAKEA03A.D LIGHTS (CONC.) m/z ab und. m/z abund. N/z abund. m/ z abund. 28.10 18 55.00 5 76.00 2 117. 10 6 29.10 3 56.00 3 77.10 4 118. 10 16 30.10 3 57.10 1 78.00 11 119. 10 16 31.10 1 58.10 1 79.00 6 120. 10 3 37.10 2 61.00 1 80.00 6 121. 10 8 38.10 4 62.00 3 81.00 1 122. 10 1 39.10 15 63.00 8 89.10 2 123. 10 1 40.20 3 64.10 4 90.10 2 131. 10 1 41,10 17 65.00 9 91.10 7 132. 20 1 42.10 32 66.00 3 92.10 4 133. 10 2
Page 219: nbi31d00
51.10 14 76.10 4 102.10 3 155.10 52.10 7 77.10 10 103.10 6 156.10 9 53.10 4 78.00 12 104.10 8 157.10 58 54.10 4 79.00 6 105.10 6 158.10 100 55.00 4 80.00 4 106.10 3 159.00 11 57.10 2 81.10 1 114.10 2 160.00 1 61.10 3 83.00 1 115.20 3 162.10 1 62.10 8 85.10 1
Page 220: nbi31d00
LIBRARY SEARCH RESULTS Scan 6098 (93.455 min) of DATA:EAKEA03A.D LIGHTS (CONC.) Library file; DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS tk Library Index t 1: 2c 3: 4: 5: 6: 7: 8: 9: 10: NORNICOTINE,N-FORMYL- N-FORMYL NORNICOTINE BIPRIOINE-2,3'-6-ONE,3,4,5,6-TETRAHYDRO- NORNICOTINE,N-BUTYRYL- (SWW 84D) NORNICOTINE,N-ACETYL- N-ACETYL NORNICOTINE NORNICOTINE NORNICOTINE,N-BUTYRYL- 5H-CYCLOPENTAPYRAZINE,6,7-HYDRO-2-ETHYL- BENZOXAZOLE,C3-ALKYL- (588 153D) 761 13 966 337 760 18 1016 1598 590 618 Scan 609B (93.455 m/n) of ORTR:ERKER03R.D I(d0 ~I.-~__~k _ 7B 92 ~ ~/' 109 0-1~ii I~~ I+~G d1119 1p7 176 II' k761 NORNICOTINE,N-PORNYL- 1Cd6l 103 1P10 176 I J 70 j iI I~I119 1 7 B 012 N-FORMYL NDRNICOTINE IBF1 70 100 176 1I ~ I 111, 5 111, 9 P' L, 0 iF966 BIPRIOINE-E.3'-6-ONE.3.4.5.6-TETRRHYORQ- 00 iB03 41 ~ 75 1,05 15 50~ ~ 70 j ~ I I 1 9 19 47 170 0 ---+++"'--- ^T .-14 1-.TL pT~^'T^^ 'T 40 60 60 10tl 120 140 160 Masc/Charpe ___ GRAPH)CSCO [M52] T: nul1. Z: Scan 5233 (82.383 min) of Y: TIC of DATA;ERKER03R,D X: Set of 4 MS Scan 6098 (93.455 min) of DATA:EAKEA03A.D b/C Match Quality 9698 9416 8691 7186 7135 7043 6816 6728 6634 5791 LIGHTS m/z (CON C.) abun d. m /z abund. m/z abund. m/ z abund. 28.1 0 68 50 .10 22 71.10 9 117. 10 14 29.1 0 38 51 .10 50 77.10 16 118. 10 29 30.2 0 IS 52 .10 21 78.00 29 119. 10 68 32.0 0 12 53 .00 14 79.10 22 120. 10 36 38.1 0 11 62 .10 8 80.00 9 130. 10 }1 39.1 0 50 63 .10 17 91.10 14 147. 20 100 40.0 0 15 64 .10 15 92.10 38 148. 20 28 41.1 0 49 65 .00 29 93.10 27 159. 10 11 42.1 0 17 66 .00 8 98.10 21 175. 10 27 43.2 0 24 67 .10 9 104.20 11 176. 10 66
Page 221: nbi31d00
LIBRARY SEARCH RESULTS Scan 3327 (57.934 min) of OATA:EAKEA02A.D MENTHOL (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: OCTADECANOL 0 1818 9377 2: UNDECANOL 0 1765 9045 3: GERANIOL, TETRAHYDRO- 0 1795 8613 4: CYCLOHEXANONE, 4-HYDROXY-2,2,6-TRIMETHYL 0 1717 8600 5: GERANIOL, TETRAHYDRO- 0 1781 8586 6: FURANONE-2-(3H)-,3-HYDROXYMe-5-METHYL- 0 716 8448 7: NONYL ALCOHOL 0 1771 8114 8: CYCLOHEXANE-1,2-DIOL,1,3,3-TRIMETHYL- 0 1629 7892 9: FURANONE-2(3H), 4- ISOPROPYL- 0 1787 7624 10: HEPTANAL 0 1433 7593 6ca1n 3327 (57.994 mtn) of ORTR:ERKER0ER.0 100JI ~I{ .il~' il r~~ ~ l 90_ B ~100 k1816 OCTRDECRNOL ~ 100J fl3 1 II i9 ~ ~ l ~'100 c m a 81765 IJNpECRNOL ~100 Q ¢ ~~ ~f9I 100 50~ 0 k1795 GERRNIOL. TETRRHY0R0- 00 ` ~ 15 6 II 70 0 u I --r 50 l00 150 200 250 300 MaasiCharge T: nul1. 2: Scan 3302 (57.610 min) of GRRPHICSCO Y: TIC of DATA:EAKEA02A.D 1MS21 X: Set of 4 MS Scan 3327 (57.934 min) of DATA:EAKEA02A.D //3io MENTHOL m/z (CONC.) ab und. m/z abund. m/z abund. m/ z abund. 28.2 0 13 54.10 20 71.10 41 97. 10 41 29.1 0 32 55.10 100 81.10 12 98. 10 10 39.1 0 14 56.10 33 82.10 16 110. 20 8 41.1 0 79 57.10 61 83.10 46 111. 10 27 42.2 0 25 67.10 25 84.10 IS 112. 10 7 43.1 0 99 68.10 14 85.10 16 125. 20 16 44.1 0 7 69.10 57 95.20 7 139. 20 9 51.2 0 4 70.10 71 96.10 13 308. 45 9 53.1 0 8
Page 222: nbi31d00
LIBRARY SEARCH RESULTS Scan 3302 (57.610 min) of DATA:EAKEA02A.D MENTHOL (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: OCTADECANOL 2: UNDECANOL 3: CYCLOHEXANONE, 4-HYDROXY-2,2,6-TRIMETHYL 4: OCTEN-2-AL,2-PROPYL- 5: OLEIC ACID, METHYL ESTER 6: GERANIOL, TETRAHYDRO- 7: NONYL ALCOHOL 8: GERANIOL, TETRAHYDRO- 9: OCT-3-EN-2-ONE 10: CYCLOHEXANONE,2,3-EPDXY-3,5,5-TRIMETHYL- Bcan 3302 (57.610 100 ~~ I -111 k1619 100lI I` ~; 111 ~ 0J 113 II I T9 ~ ~ C m a ~ Ik176S ¢ 100J {1 B k1717 CYCLOHEXRNONE. 1013 50~ 1 3 0 50 11313 GRRPHICSCD [MS2] mtn) of DRTR:ERKER02R.D 308 I 1818 9536 1765 8888 1717 8435 1452 8323 1736 8171 1795 8124 1771 7916 1781 7892 1569 7866 1526 7756 1130 10 OCTRDECRNOL 00 l1NDECRNOL 00 4-HYDRDXY-2.E.B-TRIMETHYL 100 0 Mass/Charga --'-~`~ 150E00 250 300 T: null. Z: Scan 3217 (56.492 mio) of Y: TIC of DATR:ERKERD2A.D X: Sei of 4 MS Scan 3302 (57.610 min) of DATA:EAKEA02A,D r,4„f p i, % F /Iz WNoL A 3vu i c/3~ /'fAYBf /f4A~tl~dQ MENTHOL (CONC m/z .) abund. m/z abund. m/z abund. m/ z abund. 28.10 10 56.10 30 81.10 12 110. 30 7 29.10 32 57.10 58 82.10 16 111. 10 33 N 39.10 13 58.10 5 83.10 47 112. 20 8 w 41.10 87 67,00 18 84.10 18 124. 30 4 m 00 42.20 20 68.10 13 85.10 16 125. 20 18 43.10 82 69.10 7 5.10 126. 0 5 V m Co N 44.10 4 70.10 24 96.20 10 138. 20 4 53.10 8 71.10 26 97.10 41 139. 20 9 54.10 20 77.00 4 98.10 10 308, 45 11 55.10 100 79.00 5 99.20 4
Page 223: nbi31d00
56.10 93 83.10 28 117.20 4 258.25 10 57.10 71 84.10 12 123.20 6 312.45 10 58.10 9 85.10 15 124.10 6 336.55 4 59.10 5 87.10 6 LIBRARY SEARCH RESULTS Scan 3855 (64.740 min) of DATA:EAKEA02A,D MENTHOL (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS k Library Match Index # Quality 1: OCTADECANOL 0 1818 9322 2: UNDECANOL 0 1765 9088 3: CYCLOHEXANONE, 4-HYDROXY-2,2,6-TRIMETHYL 0 1717 8862 4: GERANIOL, TETRAHYDRO- 0 1781 8791 5: GERANIOL, TETRAHYDRO- 0 1795 8715 6: FURANONE-2-(3H)-,3-HYDROXYMe-S-METHYL- 0 716 8475 7: NONYL ALCOHOL 0 1771 8178 8: TRIDECANAL 0 1478 7982 9: HEPTANAL 0 1433 7763 10: CYCLOHEXANE-1,2-DIOL,1,3,3-TRIMETHYL- 0 1629 7663 Scar, 3655 (64.740 m1n) 0 100 ~~. ,Il. .. .~i. S.3 161 / r 100 `0 N1616 OCTADECANOL ~ 1©0J 113 I II l3 ~ I r100 c 3 `k 11 63 r ~I 1 01765 LJNOECANOL ORTR:ERKER02R.0 ~ 7 396 I 161717 CYCLOHEXRNONE. 4-HYDROXY-2.2.6-TRINETHYL 100 50 0 1 9 100 400 T: null. Z: Scan 3843 (F4.582 min) of 200 MassiCharpe GRRPHICSCO Y: TIC of DRTA:EAKEAD2R.D fMS2] X: Set of 4 MS Scan 3855 (64.740 min) of DATA:EAKEA02A.D MENTHOL (CONC.) m/z abu nd. m/z abund. m/z abund. m/ z abund. 28.10 10 53.10 6 81.10 15 110. 20 6 29.10 31 55.10 100 82.10 15 111. 20 22 31.20 5 56.10 46 83.10 39 112. 20 6 32.10 4 57.10 77 84.10 13 124. 20 5 38.30 4 58.00 7 85.10 14 125. 20 19 39.10 16 65.10 4 95.10 13 126. 10 5 41.10 95 67.10 24 96.20 11 139. 20 10 42.20 22 68.10 IS 97.10 34 153. 20 6 43.10 96 69.10 52 98.10 9 181. 20 4 44.10 5 70.10 66 99.20 6 257. 25 6
Page 224: nbi31d00
53:00- 54.20 11 81.10 9 110.30 5 308.45 3 55.10 S5 82.10 11 LIBRARY SEARCH RESULTS Scan 3472 (59.804 min) of DATA:EAKEA02A.D MENTHOL (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS lt Library Match Index # Quality 1: HYDROCARBON 0 32 9257 2: TETRADECANE 0 1846 9205 3: 3-HEXANONE 0 469 9075 4: TRIDECANAL 0 1478 8454 5: PYRROLIDIN-2-CARBOXALDEHYDE 0 1474 8142 6: PYRAN-2-ONE,3,4,5,6-TETRAHYDRD-4-OH- 0 709 8045 7: 1,3-DIOXOLAN-2-ONE,4-METHYL- 0 730 8014 8: CYCLOHEXANONE, 4-HYDROXY-2,2,6-TRIMETHYL 0 1717 7909 9: SUGAR DIANHYDRIDE (SR 1770) 0 867 7811 10: FURANONE-2-(3H)-,4,5-DIHYDRO-3,40H-50HMe 0 710 7790 Bcan 347^c (59.B04 min) of ORTR:ERKER0YR.0 100, ,Iil' 1 127 171 324 ~100 /k3£ HYOROCRRBON 100 ~~ 113 ~'100 e~ I 7I r1,~ II"`000~ 100 50 0 ~ 31 I r1 M1B4B TETRROECRNE 6469 3-HEXRNONE 71 FFE100 3 I ~ ~50 50 100 150 200 250 300 Masr/CharBB T: null. Z: Scan 3350 (58.232 min) of GRRPHICSCD Y: TIC of DRTR:ERKER02R.D IMS2] X: Set of 4 MS Scan 3472 (59.804 min) of DATA:EAKEA02A.D CZ Z W CZ. 3 MENTHOL (CONC.) m/z ab un d. m/z abund. m/z abund. m/ z abund. 28.10 7 57.10 100 83.10 15 125. 20 5 29.10 26 58.00 7 84.10 8 126. 20 3 39.10 6 67.10 6 85.10 35 127. 20 9 41.10 48 68.10 6 88.10 4 141. 20 7 42.20 15 69.10 24 96.20 3 155. 10 6 43.10 91 70.10 16 97.10 10 I68. 20 3 44.20 4 71.10 61 98.10 4 169. 10 4 53.00 3 72.10 4 99.10 13 171. 00 5 54.10 7 77.10 4 111.20 7 172. 00 4 55.10 44 81.10 5 112.20 4 183. 20 3
Page 225: nbi31d00
44.10 2 68.10 7 99.10 6 146.20 1 45.10 1 69.10 8 103.10 1 147.10 8 50.10 8 70.10 6 104.10 4 148.10 2 51.10 17 71.10 1 105.10 4 161.10 1 52.00 8 74.00 1 106.10 3 175.10 10 53.10 2 75.10 1 107.10 1 176.10 34 54.10 2 76.10 2 116.20 1 177.10 4
Page 226: nbi31d00
LIBRARY SEARCH RESULTS Scan 3350 (58.232 min) of DATA:EAKEA02A.D MENTHOL (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: 2: 3: 4: 5: 6: 7: 8: 9: 10: OCTADECANOL HEPT-3-EN-2-ONE,S-ISOPROPYL- (SR131C) HEPTANONE-2, 5-ISOPROPYL-7,4-DXIDE-(BV-2 UNDECANOL HEPT-S-EN-2-ONE, 6-METHYL FURANONE-2-(3H)-,3-HYDROXYMe-S-METHYL- HEXANOIC ACID, 2-ISOPROPYL-5-OXO- CYCLOHEXANONE, 4-HYDROXY-2,2,8-TRIMETHYL TRIDECANAL HEX-3-EN-2-ONE,5-METHYL- Scan 3350 (.5B.E32 m1n) of DRTR:ERKER02R.0 t00 _ 65 111 153 90~6 ~ l 1 j~ 11 Li 3 i ,. ., n. . . . . I , .. I 03618 OCTROECRNOL I11 IP1526 100, 0J 1 3 I HEPT-3-EN-2-ONE,5-ISDPROPYL- (5R131C) 97 111 1818 9186 1528 8626 1748 8511 1765 8478 1836 8286 716 8129 1832 8075 1717 8067 1478 8012 1504 7912 100 19 B174B HEPTRNONE-2. 5-260PROPYL-7.4-C7XI0E-CBV-2 1003 65 112 15 100 50~ 3 ,.ry / r $0 0 i I I I I r 1 r l , i T EEn 50 100 150 200 250 300 MasciCharOe CP,RPH)CSCD CMS2] T: null. Z: Scan 3327 (57.934 mio) of Y: TIC of DATR:ERKER02R.D X: Set of 4 MS Scan 3350 (58.232 min) of DATA:EAKEA02A.D MENTHOL (CONC m/z .) ebu nd. mlz abund. m/z abund. m/ z abund. 28.10 8 56.10 20 83.10 29 111. 10 22 29.10 23 57.10 41 84.10 13 112. 10 5 31.10 4 58.00 8 85.10 10 113. 20 2 32.10 2 59.10 2 87.00 22 118. 10 2 39.10 13 67.00 10 93.00 3 121. 10 3 41.10 61 68.10 10 95.10 5 124. 10 3 42.20 22 69.10 34 96.20 8 125. 20 11 43.10 100 70.10 20 97.10 30 126. 20 4 44.10 6 71.10 27 98.10 7 139. 20 7 45.10 3 72.00 2 99.10 4 153. 30 3
Page 227: nbi31d00
LIBRARY SEARCH RESULTS Scan 3217 (56.492 min) of DATA:EAKEA02A.0 MENTHOL (CONC,) Library file: DATA:TOBACCO,L Library name: TOBACCO AND SMOKE COMPONENTS CAS & Library Match Index II Quality 1: MYOSMINE 2: PYRROLE[1,2aIPYRAZINE,3,6-DIMETHYL- 3: COUMARIN 4: BENZQNITRILE,2-AMINO- 5: TETRALONE-1 6: PYRIDINE,2-(1-PROPENYL)- (SBB 2360) 7: BENZIMIOAZOLE 8: IMIDAZO[1,2-a]PYRIDINE,2,3-DIMETHYL- 9: NORNICTINE,1-NITROSO- 10: BENZOFURAN 100J 9 Scan 3217 (56.492 m1n) of DRTR:ERKERQI2R.D 3 9 5 1 7 6 1125 i.. ,~61i... d~.......dn.... .... IA ... ...... .a i.. . 1 6 14 6. k10 MYOSMINE 51 78 1 0 S~ ~ 1 ~ I 116 146II K1971 PYRROLEC1,2a7PYRRZINE,3,6-DIMETHYL- 99~ 51 104 ` 118 ,~108 I I I ~ 1 f 4 6 'I/-0I 1003 50~ 'r-------r----r6 0 20 40 GRRPH]CSCD [MS2] 01861 COLIMRRIN 83_ ///64 69 I I~ II 60 60 100 MassiCharpe ~ F100 16 146 50 12 yy~`14_ _1 _- 120 140 T: null. Z: Scan 2867 (51.995 min) of Y: TIC of DATA:ERKERD2A.D X: Set of 4 MS O'C Scan 3217 (56.492 min) of DATA:EAKEA02A.D MENTHOL (CONC.) m/z abund. m/z abund. m/z abund. m/z abund. 28.10 18 53.00 2 72.00 1 92. 10 3 29.10 1 54.00 1 74.00 2 93. 10 1 30.00 1 55.10 1 75.00 3 103. 10 2 37.10 4 56.10 1 76.00 8 104. 10 9 38.10 9 97.00 1 77.10 11 105. 10 19 39.10 28 58.60 2 78.00 25 106. 10 2 40.10 10 61.00 3 79.00 2 116. 20 2 41.10 26 62.00 6 80.10 1 118. 10 100 42.10 18 63.00 16 81.00 1 119. 10 9 43.10 3 64.00 11 85.10 1 120. 10 1 10 9556 1371 7483 1861 6940 1488 6757 834 6731 543 6648 95 6407 924 6373 1013 6365 628 6333
Page 228: nbi31d00
LIBRARY SEARCH RESULTS Scan 3734 (63.178 mtn) of DATA:EAKEA02A.D MENTHOL (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Indax 0 Quality 1: HYDROCARBON 0 32 9335 2: TETRADECANE 0 1846 9289 3: 3-HEXANONE 0 469 9186 4: TRIDECANAL 0 1478 8340 5: PYRROLIDIN-2-CARBOXALDEHYOE 0 1474 8211 6: 1,3-DIOXOLAN-2-ONE,4-METHYL- 0 730 8121 7: PYRAN-2-ONE,3,4,5,6-TETRAHYDRO-4-OH- 0 709 8100 8: FURANONE-2(3H), 4,5-HYDRO-3,3-DIME-4-HO- 0 1647 7817 9: PENTADECANAL 0 1454 7737 10: SUGAR DIANHYDRIDE (SR 177D) 0 867 7666 Scan 3734 [63.176 10~JI 1l3 ~f .!l ~g d mi n) of C1RTR: ERKER02R. 0 33.8 . 183 225 7b32 HYDROCARBON 1001I 127 ~1®0 0J I 7 il '13 d : ! C 100J1 11311 il a r I 81846 TETRADECANE k469 3-HEXRNONE 1003 F100 50~ ~ 3 J I llm0 ~50 100 206 300 __ Masr/Charge T: nul1. Z: Scan 3559 (60.923 min) of GRRPH]CSCO Y: TIC of DRTA:EAKER02R.D [MS2J X: Set of 4 MS Scan 3734 (63.178 min) of DATA:EAKEA02A.D ~r /aC C27 -e~ . YY / 44-~4 MENTHOL m/z (CONC.) abu nd. m/z abund. m/z abund. m/ z abund. 28.2 0 7 57.10 97 84.10 8 126. 20 4 ut r 29.1 0 24 58.10 4 85.10 38 127. 20 10 W m 32.0 0 3 67.00 6 86.00 3 140. 20 3 w 39.1 0 6 68.10 4 96.20 2 141. 20 7 ~ 41.1 0 51 69.10 19 97.10 9 154. 20 2 m ~ ~ 42.2 0 16 70.20 15 98.20 5 155. 10 6 43.1 0 100 71 .10 63 99.10 16 169. 20 5 44.1 0 4 72.00 4 111.10 7 183. 20 5 53.0 0 3 81.10 3 112.20 S 197. 20 4 55.1 0 36 82.10 S 113.20 13 225. 35 3 100
Page 229: nbi31d00
m LIBRARY SEARCH RESULTS Scan 3559 (60.923 min) of DATA:EAKEA02A.D MENTHOL (CONC,) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index t Quality 1: BETA-NICOTYRINE 2: QUINOXALINE,DIMETHYL- (SBB 174) 3: PYRIDINE,2-(N-METIIYLPYRROL-2-YL) 4: PYRIDINE,3-(2-METHYL-I-PYRROLYL)- 5: UNKNOWN (NICOTINE LIKE) (SWW 206D) 6: PYRROLE,N-(2-PYRIDYLMETHYL)- 7: QUINOXALINE,2-ETHYL- 8: INDOLE,1,2,3-TRIMETHYL- 9: QUINOLINE,DIMETHYL 10: QUINOLINE,2,8-OIMETHYL- (SBB 1730) (SBB 230D) Scan 3559 (60.923 mfn) of ORTReERKER02R.0 42 63 78 89 116 13® 5 6~I1. .I. Iln.. . .,L... ... .... Ilrr. . ..nli... .. ..a.. .A1.. . h.. i. #538 BETR-NICQTYRINE 4 E 79 90 117 130 i 1 n u I 536 9584 609 9403 291 9182 1011 8330 349 8286 1590 7631 1125 7627 1068 5938 559 S767 561 5464 100 ~ / f'0a 15 ~~ TS #609 QLIINQXRLINE,OIMETHYL- (S68 174) ¢ 100 -~ 3 39 65~ 78 130 A I 100 JI 111 I 1 151I GRRPHICSCO [MS'23 T: null. Z: Scan 3472 (54.804 min) of Y: TIC of DATR:EAKEA02R.D X: Set of 4 MS Scan 3559 (60.923 min) of DATA:EAKEA02A.0 CIA-6 6/ 9~ Gvo/J Fe T MENTHOL N/z (CONC.) abun d. m/z abund. M/z abund. m/ z abund. 28.1 0 12 63.00 16 86.00 2 116. 10 12 29.1 0 1 64.10 4 87.00 3 117. 10 11 ~ 32.1 0 1 65.00 4 88.00 3 118. 10 2 ~ 37.1 0 3 66.10 1 89.10 12 119. 10 1 w 38.1 0 5 67.00 1 90.00 9 128. 10 3 m au '1 39.1 0 14 69.10 1 91.00 3 130. 10 30 B 40.1 0 3 70.10 1 92.00 1 131. 10 7 DD :n 41.1 0 6 71.10 1 93.10 1 132. 20 1 42.1 0 16 73.10 1 97.10 1 133. 10 1 43.1 0 3 74.00 4 97.90 1 142. 10 5 #291 PYRIOINE,2-(N-METHYLPYRROL-E-YL) 65 130 39 ~ 79 r / 1 / II 40 60 60 100 120 140 Masc/Charpa
Page 230: nbi31d00
1B 82.345 BU 0,422 1043113366 19 82.423 VV 0,066 206803429 20 82.529 UB 0.110 376670680 21 93.478 BB 0.343 177789153 LIBRARY SEARCH RESULTS Scan 1350 (24.350 min) of DATA:EAKEA02A.D MENTHOL (CONC.) Library file: DATR:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS 81.436 82.355 82.355 82.436 82.436 82.724 92.891 93.989 CAS # Library Index # 1: 2: 3: 4: 5: 7: 8: 9: 10: CYCLOHEXANONE, 2-ISOPROPYL-S-METHYL- NONA-2,4-DIENAL CYCLOTENE PENTENAMIDE-3, 4-METHYL- PENTEN-4-AL,2-METHYL- OCTEN-6-AL,3,7-DIMETHYL- CARVOMENTHONE (CYCLOHEXANONE,2-ME-S-ISOP 2-(5H)-FURANONE,2,4-DIMETHYL- (SNN 88D) NONA-2,6-DIEN-1-OL OLEIC ACID, METHYL ESTER 100J a Stan 1350 (24.352 mtn) af ORTR:ERKER02R.0 k1769 ,~ ~ 97 -,ti 139 iP. l I I~I. i1f5i , i IL 69, Ji, .aA, .1I.^- 1 12 1/ CYCLOHEXRNONE, 2-ISOPROPYL-5-METHYL- 9 ~ 7 41 ~ ~~ II 9 1 / trl 139 ( 1769 1447 1625 1343 1460 1453 1673 365 1773 1736 N1447 NONR-2.4-0IENRL 100, / r100 0 J 4i 1003 f'I 50~ 4l,'ll \ N 112 ~ ~ , ~ 0 0 20 40 B0 60 100 120 140 Macz/Ch GRAPHICSCO 11121 s ~E'100 ~'S0 T: null. Z: TIC of DRTA;EAKEA02R.D Y: TIC of DATR:EAKEAD2A.D X: Set of 4 MS Scan 1350 (24.350 min) of DATA:EAKEA02A.D MENTHOL (CONC.) m/z abu nd. m/ z abund. m/z abund. m/ z 28.10 14 55. 10 61 82.20 4 98. 00 29.10 32 56. 10 28 83.10 23 110. 20 30.90 3 57. 10 19 84.10 14 111. 20 39.10 43 65. 10 4 85.10 4 112. 10 41.10 100 67. 10 14 93.10 5 113. 10 42.10 24 69. 10 56 94.10 4 121. 10 43.10 41 70. 10 29 95.10 13 125. 10 44.10 3 71. 00 11 96.20 4 139. 20 51.10 4 77. 10 3 97.10 22 154. 10 53.00 14 79. 10 5 01625 CYCLOTENE ' + 69 I` Match Quality 9508 8272 7804 7764 7607 7506 7427 7216 7084 7050 /SO Hew~ OL" abund. 6 4 25 64 6 4 4 28 17
Page 231: nbi31d00
51.20 4 73.00 5 LIBRARY SEARCH RESULTS Scan 3940 (65.836 min) of DATA:EAKEA02A.D MENTHOL (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS 4-. 4b - - - - - 9 CAS # Library Match Index # Quality 1: BENZOPHENONE 2: BENZOIC ACID, METYL ESTER 3: PROPIOPHENONE 4: BENZIL 5: BENZOIC ACID, ETHYL ESTER 6: ACETOPHENONE 7: PHTHALIDE 8: PHTHALIDE 9: BENZYALDEHYDE 10: BENZAMIDE 01798 BENZOPHENONE Scan 3940 (65.636 m1n) of ORTR:ERKER0ER.0 50 (' 100, ~rl 51 ~77 41 127 153 00 19P ~ u c N 5m _ ' - I I 51 a k1544 5 100 50 51 -- ¢ I~ n 100 50 0 GRAPHICSCO [MS2] 77 1~05 152 192 i BENZOIC RCID. METYL ESTER ~ 13•E ~77 05 ' i6176 PROPIOPHENONE 77 124 105 ~ 60 100 120 140 MarsiCharp® 1798 9935 1544 8735 176 8669 802 8642 1543 8532 440 8457 1841 8320 54 8171 57 7779 181 7692 r100 100 ~•,•+0 0 160 190 T: nu11. Z: Scan 3855 (64.740 min) of Y: TIC of DATR:ERKER02A.D X: Set of 4 MS Scan 3940 (65.836 min) of DATA:EAKEA02A.D MENTHOL (CONC m/z .) abund. m/z abund. m/z abund. m/ z abund. 28.10 2 52.10 4 74.00 7 111. 20 1 29.20 2 52.90 2 75.00 5 126. 10 1 32.10 1 54.00 1 77.00 83 127. 10 1 37.00 1 55.10 4 78.00 6 150, 10 1 38.10 2 56.10 2 81.90 1 161. 10 3 39.10 5 57.10 4 83.00 2 152. 10 4 41.20 3 62.10 2 85.10 1 153. 10 4 42.20 1 63.00 2 87.00 1 154. 10 3 43.10 3 69.10 2 97.10 1 181. 10 12 45.10 I 70.10 2 98.10 1 182. 00 63
Page 232: nbi31d00
3 LIBRARY SEARCH RESULTS Scan 3843 (64.582 min) of DATA:EAKEA02A.D MENTHOL (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS t Library Match Index # Quality 1: GERANIOL, TETRAHYDRO- 0 1781 8690 2: GERANIOL, TETRAHYDRO- 0 1795 8596 3: NONYL ALCOHOL 0 1771 8566 4: UNDECANOL 0 1765 8497 5: BUTANONE-2, 3,3-OIMETHYL-4-HYDROXY- 0 1721 8460 B: OC1'ADECANOL 0 1818 8289 7: HEXANAL 0 1438 8179 8: PYRAN-2-ONE(2H),6,6-DIME-4-ISOPRYL-TETRA 0 1763 8125 9: ACETAMIDE,N-ALLYL- 0 747 8067 10: PYRAN-2-ONE(3H), 5,6-DIHYDRO-4-ISOPROPYL 0 1672 8003 Scan 3643 (64.58E mfn) of ORTR:EAKER08R.6 10®J R3~1 B3 1~ g 185 .J ~. ~0 ~. b. ,i,,. . ~ , . . I / 0 289 _ 91E ~ 257 ~. ~. ~ k1761 GERRNIDL. TETRRHYORO- ~ Il s~ k1795 GERANIOL. TETRRHYORO- 5 fomI fl16i~4I 100 U~ ~. ~ ~ I/ ~I f/l6 0 *1771 NONYL ALCOHOL Masc/Charae 300 L.. T: nul1. Z: Scan 3734 (63.178 min) of GRRPHICSC6 Y: TIC of DATA:ERI(EA02A.D [MS2] X: Set of 4 MS Scan 3843 (64.582 min) of DATA:EAKEA02A.0 a(-. L./~ ~ MENTHOL (C m/z ONC.) abund. m/z abund. m/z abund. m/ z abund. 28.20 19 60.00 15 95.10 9 125. 20 9 29.10 52 61,00 10 96.10 7 129. 10 11 31.10 13 67.10 20 97.10 26 139. 20 6 Ln 39.10 17 68.10 11 98.10 10 157. 10 5 r 41.10 94 69.00 37 99.10 6 171. 10 5 W m 42.20 21 70.10 20 101.00 10 185. 10 10 co J 43.10 100 71.10 26 109.20 5 213. 25 7 O ro 00 44.10 8 73.00 19 111.20 17 239. 35 16 53.10 8 79.00 6 112.10 7 240. 35 S 54.20 12 81.00 14 115.10 5 256. 45 10
Page 233: nbi31d00
4l 0l'8tl 4 0l'LL S 00'SS b 0l'LLl 9 0Z'LlI Z 00'9L Z 0L'US ££ 01'9Ll 1 01'01 1 00'SL 2 00'2S 0l 0I'SLt £ 0l'90! l 0l'4L L 0l'Z9 I 00't9t £ 0i'50l I 0t'tL 91 0t'IS Z 0l'84l 4 0l'40l 9 0l'0L 8 0l'0S 8 01'01 1 0Z'201 8 01'69 1 0l'SV L A7'9bl 9 Al'6A q 0l'A9 7 0 l'4p
Page 234: nbi31d00
59-.51.10 51 73.10 1 106.10 7 LIBRARY SEARCH RESULTS Scan 3989 (66.469 min) of DATA:EAKEA02A.D MENTHOL (CONC.) Library fiie: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS II Library Match Index # Quality 1: HYDROCARBON 0 32 9411 2: TETRADECANE 0 1846 9230 3: 3-HEXANONE 0 469 9132 4: TRIDECANAL 0 1478 8332 5: PYRROLIDIN-2-CARBOXALDEHYDE 0 1474 8184 6: 1,3-DIOXOLAN-2-ONE,4-METHYL- 0 730 8104 7: PYRAN-2-ONE,3,4,5,6-TETRAHYDRO-4-OH- 0 709 8024 8: FURANONE-2(3H), 4,5-HYDRO-3,3-DIME-4-HO- 0 1647 7712 9: PENTAOECANAL 0 1454 7690 10: SUGAR DIANHYDRIDE (SR 177D) 0 867 7659 01846 TETRROECRNE 85 ' I k469 3-HEXRNONE 1 0 03 Ek1013 50~ I 3 I 57 I 0 1'S0 0 ---~- ~ ~~0 50 10 10 0 150 200 Mats/Charge T: nul1. Z: Scan 3940 (65.836 min) of GRAPHICSCO Y: TIC of DATA:ERNEA02A.D [MS2] X: Set of 4 MS Scan 3989 (66.469 min) of DATA:EAKEA02A.D IlC ,,,, ~-,T C1 y MENTHOL (CONC.) m/z ab und. m/z abund. m/z abund. m/ z abund. 28.10 9 57.10 97 84.10 8 125. 20 4 29.10 19 58.10 4 85.10 41 126. 20 4 39.10 6 67.00 6 86.10 4 127. 20 10 cn 41 10 46 68 10 4 96 10 4 140 30 4 ~ . 42.20 17 . 69.10 21 . 97.10 . 12 141. 20 6 w m 43 10 100 70 10 15 98 20 6 154 20 3 tb ~ . 44 10 5 . 71.10 62 . 99.10 . 15 155. 10 5 m . ~. 45.10 3 72.00 4 110.10 2 169. 20 4 53.10 2 81.10 3 111.20 7 183. 20 3 55.10 41 82.10 6 112.20 4 197. 20 4 Scan 3989 C66.469 mtn) of ORTR:ERKER02R.0 ~~ B5 113 r700 14 1 189 197 jjl",000 032 HYDROCARBON ~ 13 ~8 II 57 I I 65i1 11 ~
Page 235: nbi31d00
55.00 36 LIBRARY SEARCH RESULTS Scan 4770 (76.533 min) of OATA:EAKEA02A.D MENTHOL (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS 4 Library Match Index 71 Quality 1: NICOTINAMIDE,N-METHYL (SWW27D) 2: PYRIDINE,3-PROPIONYL- 3: PYRIDINE,4-PROPIONYL- 4: 3-ACETYLPYRIDINE 5: PYRIDINE,3-BUTYRYL 6: PYRIDINE,4-ACETYL- 7: NICOTINAMIDE 8; PYRIDINE,4-PROPIONYL- 9: 3-PYRIDINECARBOXALDEHYDE (NICOTINALDEHYD 10: KETONE,CYCLOPROPYL-3-PYRIOYL (SWW 116D) 100- 0 u c m Scan 4770 [76.533 mtn] of ~~ ~26 1 71 76 P .... .......... .H?....I . ! „ 1.. 02513 NICOTINRMIOE.N-METHYL 1 S N I 7B CSWW2707 ( 106 135 I II a 6476 PYRIOINE.S-PROPIONYL- 3 11 S 40 ~1 4 1 3~ [' 00 ii 76 106 'L01 01812 PYRI!]INE.4-PROPIONYL- 100~ 2~B 51 7B 135 F100 50'~,/ l1 i 106 i~50 --~~--- w 40 60 60 100 12 12 Masr/Char e ----_. - ---- -0---_. --- --- -- GRAPH)CSCO fMS?I 250 9606 476 8983 1613 8361 38 7570 306 7154 475 7042 759 6856 477 6697 173 6511 297 6491 ORTR:ERKER02R.0 105 (100 '~''I 1136 19 I`I01 T: nu11. Z: Scan 4524 (73.361 min) of Y: TIC of DATR:ERKEA02A.D X: Set of 4 MS Scan 4770 (76.533 min) of DATA:ERKEA02A.D MENTHOL (CONC,) m/z ab und. m/z abund. m/z abund. m/ z abund. 28.10 24 42.10 I 56.00 1 80. 10 2 29.10 6 43.10 4 57.10 3 81. 10 1 30.10 6 44.20 2 58.00 12 93. 00 2 31.10 2 45.10 5 66.00 2 105. 20 13 ut H 32.00 36.10 1 1 49.20 50.10 9 40 67.10 69.10 2 106. 2 107. 10 10 64 6 w m a V 37.10 4 51.10 66 71.10 2 123. 10 16 m ~ 38.10 7 52.10 18 75.00 4 124. 10 1 ut 39.10 7 53.00 10 76.10 5 135. 10 69 40.10 2 54.10 1 78.00 100 136. 10 28
Page 236: nbi31d00
LIBRARY SEARCH RESULTS Scan 4359 (71.238 min) of DATA:EAKEA02A.D MENTHOL (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CRS R Library Match Index # Quality 1: GERANIOL, TETRAHYDRO- 0 1781 8545 2: GERANIOL, TETRAHYDRO- 0 1795 8423 3: ACETAMIDE,N-ALLYL- 0 747 8352 4: BUTANONE-2, 3,3-DIMETHYL-4-HYDROXY- 0 1721 8327 5: NONYL ALCOHOL 0 1771 8326 6: HEXANAL 0 1438 8216 7: UNDECANOL 0 1765 8199 8: OCTADECANOL 0 1818 8034 9: SUGAR DIANHYORIDE (SR 184D) 0 869 7968 10: PYRAN-2-ONE(2H),6,6-DIME-4-ISOPRYL-TETRA 0 1753 7906 Scan 4359 (71.i3B m1n) of DRTR!ERkER08R.D IIjI,//(((1 9~{j 129 16`3 241 ~3 34..0.~~ r100 431 YL i41 I7T.jL I~., A.. II i. ` ~ ~Cg 1 sl~„-. 01781 GERRNIOL, TETRRHYORO- ~ 00 ~ 01795 GERRNIOL. TETRRHYORp- /II 1\l. r106 43 11 1161 I N747 RCETRMIOE.N-RLLYL- 100 f/ 99 50 43 7 ~' 0- ':( 3' t 0 100 200 Mass/CharBa 900 T: null. Z: Scan 027 (66.96D min) of GRAPH]CSCD Y: TIC of DATA:ERKEA02A.D [MS27 X: Set of 4 MS Scan 4359 (71.238 min) of DATR:EAKEA02A.D MENTHOL (CONC.) m/z abu nd. m/z abund. m/z abund. m/ z abund. 28.20 13 61.00 15 87.00 7 129. 10 20 ~ 29.10 39 67.10 12 95.10 10 139. 20 6 r 39.10 9 68.10 8 96.20 7 143. 10 5 w m 41.10 89 69.10 35 97.10 26 171. 10 5 ~ 42.20 19 70.10 17 98.10 9 185. 20 17 J m ~ 43.10 99 71.10 33 99.10 7 199. 20 4 W 44.10 S 73.10 31 101.00 9 241. 25 13 45.10 5 74.10 4 109.20 5 267. 25 28 53.00 6 79.10 3 111.20 16 268. 25 4 55.10 74 81.10 9 112.20 4 284. 35 14
Page 237: nbi31d00
44.10 2 68.10 7 99.10 6 146.30 1 45.10 1 69.10 8 103.10 1 147.10 8 50.10 8 70.10 6 104.10 4 148.10 1 51.10 17 71.10 1 105.10 3 161.10 1 52.10 7 74.10 1 106.10 3 175.10 10 53.00 2 75.00 1 116.20 1 176.10 33 54.00 2 76.00 2 117.10 6 177.10 4
Page 238: nbi31d00
18 44.053 VV 0.133 1029546854 43.895 44.405 19 44.424 VU 0.036 5511900 44.405 44.459 20 44.479 VV 0.070 10025434 44.459 44.645 21 51.396 VV 0.022 178728 51.370 51.420 22 57.424 PV 0.065 6919628 57.270 67.439 23 57.452 VV 0.119 9572406 57.439 57.637 24 57.652 VU 0.041 612193 57.637 57.707 25 61.861 PU 0.043 417461 61.781 61.875 26 61.896 VV 0.037 232573 61.875 61.924 27 66.650 PV 0.102 2748172 66.573 66.824 28 83.098 PU 0.162 27030042 82.752 83.161 29 83.172 VV 0.024 2481486 83.161 83.186 30 83.197 VV 0.025 2464426 83.186 83.214 31 83.236 VV 0.103 9021620 83.214 83.364 32 83.582 VV 0.055 742749 83.535 83.653
Page 239: nbi31d00
Data file: DATA:ACHEA07A.D File type: GC / MS DATA FILE Name Info: LIGHTS-2 Misc Info: Operator : JNS Date : 13 Aug 86 1:49 am Instrment: MS_5970 Inlet : GC Sequence index : 1 Als bottle num : 7 Replicate num : 1 9.0E6 TIC of ORT R:RCHER67R.0 O E. 6EF, 7.OE6 r m 6.0E6 u c 5 BE6 m . ~ c 3 4.BE6 a ¢ 3. mEB 2.0E6 m ~ C~= V1 md1' m 14 i6 e 1 . OEE wr rt1Ym m34 a EKe1io7 mY,'~ . m ~ m m m ~ m m i . QO fd m ~ 10 20 30 40 5R 60 7B 60 90 106 Ttme (mtn.) GRRPHICSCO [MS2] T: TIC of DViTR:RCHEAD3A.D Z: TIC of DRTA:ACHEAD4R.D Y: TIC of DATA:RCHERDSfl.D X: TIC of DRTA:RCHEAD7A.D TIC of DATA:ACHEA07A.D L TG,u,TS-2 Peak.# Ret Time Type Width Area Start Time End Time 1 1 8.270 VU 0.024 164440 18.242 18.280 2 1 8.321 VU 0.105 2334449 18.280 18.537 3 2 2.417 PV 0.114 12477418 22.277 22.560 4 2 2.571 VU 0.040 515878 22.560 22.635 5 2 3.704 vv 0.036 328589 23.666 23.719 6 2 3.999 PV 0.013 118855 23.984 24.013 7 2 4.421 PV 0.024 153304 24.379 24.429 8 2 4.446 vv 0.021 217454 24.429 24.455 9 2 4.482 vv 0.041 564948 24.455 24.508 10 2 4.523 VU 0.031 299B49 24.508 24.560 11 2 6.865 PU 0.051 603680 26.799 26.900 12 2 6.915 VU 0.026 229453 26.900 26.976 13 3 1.309 PU 0.069 1255166 31.279 31.385 14 3 1.393 vv 0.040 530371 31.385 31.473 15 3 3.499 PV 0.063 532582 33.420 33.549 )s 3 3.883 PV 0.112 36694900 33.742 34.074 17 43 .886 PV 0.254 1720396794 43.202 43.895
Page 240: nbi31d00
57.10 82 83.10 26 116.10 58.00 6 84.10 10 117.20 59.10 5 85.10 1B 125.20 60.00 22 86.20 4 LIBRARY SEARCH RESULTS Scan 4524 (73.361 min) of DATA:EAKEA02A.D MENTHOL (CONC.) 9 286.35 12 10 340.45 16 10 341.45 5 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS 1L Library Match Index III Quality 1: TETRADECANE 0 1846 8426 2: HYDROCARBON 0 32 8395 3: PHTHALIC ACID, DI-(2-ETHYL)-HEXYL ESTER 0 737 8344 4: 3-HEXANONE 0 459 8251 5: TRIDECANAL 0 1478 7646 6: PYRROLIDIN-2-CARBOXALDEHYOE 0 1474 7398 7: PYRAN-2-ONE,3,4,5,6-TETRAHYDRO-4-OH- 0 709 7393 8: 1,3-DIOXOLAN-2-ONE,4-METHYL- 0 730 7322 9: PENTADECANAL 0 1454 7040 10: SUGAR DIANHYDRIDE (SR 1770) 0 867 7026 Scan 4524 (73.361 mtn) of DRTRtERKER02R.o BS 113 A 169 223 r1B0 k1646 TETRRDECRNE ~ 65 3 III 5'il If '8 M32 HYDROCARBON c 3 ,I ~ 5 113 r n 100J '13 I Si~ I Bil ~, II~sOB ¢ ip737 PHTHRLIC RCID, 0I-(2-ETHYL)-HEXYL E5TER 100~ 41 E100 50'j. / I 5 t4 9 50 0~ --1 r 0 50 100 150 200 ` Mass/CharBe T: null. Z: Scan 4359 (71.238 Inin) of GRRPHICSCD Y: TIC of DATA:EAREAD2A.D [MS2l X: Set of 4 MS Scan 4524 (73.361 min) of DATA:EAKEA02A.D MENTHOL (CONC.) m/z abun d. m/z abund. m/z abund. m/ z abund. 28.20 14 56.20 23 83.10 11 113. 20 13 29.10 33 57.10 100 84.10 8 121. 10 5 31.20 5 58.10 6 85.10 38 125. 10 11 39.10 13 67.00 7 86.10 6 126. 20 4 41.10 55 68.10 6 97.10 16 127. 10 8 42.20 18 69.10 24 98.20 5 141. 20 8 43.10 95 70.10 14 99.10 16 149. 10 79 44.10 7 71.10 60 104.10 6 150. 00 8 45.10 8 73.10 7 105.00 4 155. 10 5 53.00 5 76.00 6 111.20 8 169. 10 5
Page 241: nbi31d00
LIBRARY SEARCH RESULTS Scan 4027 (66.960 min) of DATA:EAKEA02A.D MENTHOL (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS II Library Match Index # Quality 1: HEPT-3-EN-2-ONE,S-ISOPROPYL- (SR131C) 2: OCTADECANOL 3: HEPTANONE-2, 5-ISOPROPYL-7,4-OXIOE-(BV-2 4: HEPT-5-EN-2-ONE, 6-METHYL 5: HEXANOIC ACID, 2-ISOPROPYL-5-OXO- 6: UNDECANOL 7: DIDXOLANE-1,2,2,2-DIMETHYL-4-HYDROXYME- 8: PENTANOIC ACID,2-METHYL-4-OXO- 9: VALERIC ACID, 2-METHYL-4-OXO- (SWW9D) 10: FURANONE-2-(3H)-,3-HYOROXYMe-S-METHYL- 57 97 125 2Z4 1528 8886 1818 8836 1748 8716 1836 8421 1832 8320 1765 8107 843 8077 660 8047 241 8015 716 7983 300 N1526 HEPT-3-EN-2-0NE.5-ISOPROPYL- (5R1S1C) p1 12121 1 113 69 97 125 ('100 J ! ~ U 0 I I I ~ "001 c N '° 41616 OCTRDECRNOL Scan 4027 (68.960 m1n) nf DRTR!ERiCERO>?R.0 1 3 97 ir I I 1 II~1 K1746 HEPTRNONE-2, 5-I90PROPYL-7,4-DXIOE-CBV-2 10a 69 112 119 ~-300 S3 ! ~ f %S5 50 ^~------ia 50 100 ISO 2013 MarriCharle_ GRAPH)CSCO [MSZ] T: null, Z: Scan 3989 (66.469 min) of Y: TIC of DRTR:ERKER02R.D X: Set of 4 MS Scan 4027 (66.960 min) of OATA:EAKEA02A.D MENTHOL (CON m/z C.) abu nd. m/z abund. m/z abund. m/z abund. 28.20 6 56.10 18 79.10 2 99.20 2 29.10 16 57.10 36 81.10 6 110.20 3 39.10 5 57.80 3 82.10 15 111.20 16 41.10 45 61.00 28 83.10 26 112.20 3 42.30 17 67.00 10 84.10 11 124.20 3 43.10 100 68.10 9 85.10 10 125.20 8 44.10 4 69.10 27 95.10 4 126.20 3 53.00 3 70.10 15 96.10 7 139.20 4 54.20 8 71.10 16 97.10 25 224.35 2 55.10 39 73.10 5 98.10 7
Page 242: nbi31d00
n LIBRARY SEARCH RESULTS Scan 5220 (82.342 min) of DATA:EAKEA02A.D MENTHOL (CONC.) Library file: DATA:TOBRCCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS t Library Match Index it Quality 1: COTININE 2: N-METHYL ANABASINE (SWW 20) 3: PIPERIDINE,1-ETHYL.- 4: 1,5-DIMETHYL-2-PYRROLIDINONE 5: NORNICOTINE,N-ETHYL- (SL 39D) 6: PYRROLIDIN-2-ONE,1,5-DIMETHYL- 7: PYRIDINE,3-()-ET-2-PYRROLIDINYL)- 8: PIPERIDINE,1-METHYL- 9: PIPERIDINE,2,3-DIMETHYL- 10: 2-PIPERIDONE,6-METHYL- 12 9758 237 9138 1136 8718 40 8643 878 8153 1378 8041 999 7823 1143 7303 1139 6773 787 6752 9can 5220 (62,342 min) Df DRTRtERKER02R.D (100 42 51 ~ 147 178 1 19 /1...,~. 1... .~LII . . ~.n......~.. 95~... . .~~~. .~N .. ... ..i. . - i~. 42 I / 96 8237 N-METHYL RNRBRSINE 42 70 r 1/ 16 dl I 14,7~ 17-6M1 i ~ (sww zD) 1/ I9 Oc 01128 PIPERIDINE.1-ETHYL- 100 f J 100 30 42 96/ I lj 2 50 0 1 1^ ^'1 1 T^ b 0 22 40 60 B0 100 120 140 160 MasriCharpe GRRPH]CSCO [MS2I T: nul). Z: Scan 4770 (76.533 min) of Y: TIC of DATA:EAKEA02A.D X: Set of 4 MS Scan 5220 (82.342 min) of DATA:ERKEA02A.D MENTHOL (CONC.) m/z ab und. m/z abund. m/z abund. m/ z abund. 28.10 18 55.00 5 77.10 4 117. 10 6 29.10 3 56.00 2 78.10 10 118. 10 15 30.10 3 57.00 1 79.10 6 119. 10 16 31.10 1 58.10 2 80.10 5 120. 10 4 37.10 1 61.00 1 89.00 2 121. 10 7 38.10 4 62.00 3 90.10 2 122. 10 1 39.10 13 63.00 8 91.10 7 123. 10 1 40.20 3 64.10 4 92.00 4 131. 10 1 41.10 17 65.00 9 93.10 2 132. 20 1 42.10 32 66.10 3 94.10 1 133. 10 2 012 COTININE /I
Page 243: nbi31d00
LIBRARY SEARCH RESULTS Scan 5234 (82.528 min) of DATA:EAKEA02A.D MENTHOL (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS 1: COTININE 2: N-METHYL ANABASINE (SWW 20) 3: PIPERIDINE,1-ETHYL- 4: 1,5-DIMETHYL-2-PYRROLIDINONE 5: NORNICOTINE,N-ETHYL- (SL 39D) 6: PYRROLIDIN-2-ONE,1,5-DIMETHYL- 7: PYRIDINE,3-(I-ET-2-PYRROLIDINYL)- 8: PIPERIDINE,1-METHYL- 9: PIPERIDINE,2,3-DIMETHYL- 10: 2-PIPERIDONE,6-METHYL- Scan 5234 (62 526 ! DRTR:ER 1/ 19 CAS # Library Match Index # Quality 0 12 9730 0 237 9159 0 1136 8730 0 40 8663 0 878 8152 0 1378 8062 0 999 7823 1 1143 7338 1 1139 6828 0 787 6806 E110219. 0 147 iio 012 COTININE 42 I 118 147 17„61 1 I M297 N-METHYL RNRBR9INE CSWW 207 42 70 / 119 / taa Ik1 136 PIPERIOINE. 1-ETHYL- 100 / 100 42 / 112 50 / 96 ~ 50 0 + ~~ r i i ~-T r 0 0 20 40 60 60 100 120 140 160 _ Massi[har0e T: null. Z: Scan 5226 (82.422 min) of GRRPH]CSCD Y: TIC of DATA:ERKERD2A.D LMS2] X: Set of 4 MS Scan 5234 (82.528 min) of DATA:EAKEA02A.D MENTHOL (CDNC.) m/z ab und, m/z abund. m/z abund. m/ z abund. 28.10 18 55.00 5 77.10 4 118. 10 15 29.10 3 56.00 3 78.00 11 119. 10 16 30.10 3 57.10 1 79.10 6 120. 10 3 31.10 1 58.10 1 80.10 5 121. 10 7 37.10 1 61.10 1 89.10 2 122. 10 1 38.10 5 62.10 3 90.10 2 123. 10 1 39.10 14 63.00 8 91.10 7 131. 10 1 40.20 3 64.10 3 92.10 5 132. 20 1 41.20 17 65.00 9 93.10 2 133. 10 2 42.10 34 66.10 3 94,10 1 134. 10 1 42 L.. .d,l~...
Page 244: nbi31d00
LIBRARY SEARCH RESULTS Scan 1214 (22.573 min) of DATA:ACHEA07A.D LIGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index It Quality 1: PENTADECANAL 0 1454 7864 2: DECANAL 0 1561 7826 3: TRIDECANAL 0 1478 7615 4: UNDECANAL 0 1764 7368 5: CYCLOHEXANONE-1,2-DIOL, 4-METHYL- 0 1660 7364 6: 3-HEXANONE 0 469 7115 7: FURAN-2-ONE-(3H),4,5-DIHYDRO-3-HYDROXY- 0 1525 7114 8: FURANONE-2(3H), 4,5-HYDRO-3,3-DIME-4-HO- 0 1647 7073 9: OCTANE-2,3-OIONE 0 1558 6986 10: FURANONE-2(3H), 4,5-HYDRO-3-HYDROXY-3-ME 0 1646 6881 Scan 1214 (28.573 mtn) of ORTR:RCHER07R.G 100 Gf / ] 'B I 3'c 41 I r48 61454 PENTROECRNRL ]0D 1 c"f9 4~1 I43 5~ 8 i 71 BP I r100 100I ~ 0 11B /h1561 OECRNRL 41 r 5 = B2 100 ~ ~ I 1 I ~~ 01478 TRIO/ECRNRL I68 82 Ft100 9 1, I l Ii I 100] 2L•4 50 a.l/,1 49 5.I~ I ~ C50 iI rllJ[U 0 50 80 70 80 MassiCharBe Ts null. Z: Scan 1202 (22.420 min) of GRAPH]CSCO Y: T]C of DRTR:RCHEA07A.D CMS27 X: Set of 4 MS Scan 1214 (22.573 rnin) of DATA:ACHER07A.D LIGHTS-2 m/z abund. m/z abund. m/z abund. m/z abund. 28.15 96 32.15 47 43.15 83 57.15 100 29.15 76 41.15 69 55.15 57 71.15 69
Page 245: nbi31d00
LIBRARY SEARCH RESULTS Scan 5226 (82.422 min) of DATA:EAKEA02A.D MENTHOL (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Index # 1: COTININE 2: N-METHYL ANABASINE (SWW 2D) 3: PIPERIDINE,I-ETHYL- 4: 1,5-OIMETHYL-2-PYRROLIDINONE 5: NORNICOTINE,N-ETHYL- (SL 39D) 6: PYRROLIDIN-2-ONE,1,5-DIMETHYL- 7: PYRIDINE,3-(1-ET-2-PYRROLIDINYL)- 8: PIPERIOINE,1-METHYL- 9: PIPERIDINE,2,3-DIMETHYL- 10: 2-PIPERIDONE,6-METHYL- Scan 5226 (62.422 min) uf 42 51 I. .dA~... ~i..e....e. gge.. 42 ! 12 237 1136 40 878 1378 999 1143 1139 787 ORTR:ERKER02R.0 119 147 17E r100 / .IIn.. .... . /k12 COTININE lJ I 116 96 di 147 175~r100 i~~ 0237 N-METHYL RNRBR/5INE (SWW 20) 42 70 / 119 1'100 lr IP119E PIPERIDINE.t-ETHYL- 100 50 42 96 112 0 20 40 E0 60 100 120 140 160 Maac/Charpe GP.RPH]CSCp [MS2] T: null. Z: Scan 5220 (82.342 min) of Y: TIC of DRTA:EAKER02A.D X: Set of 4 MS Scan 5226 (82.422 min) of DATA:EAKEA02A.D Match Quality 9757 9179 8759 8688 8166 8084 7851 7350 6828 6806 MENTHOL (CONC.) m/z ab und. m/z abund. m/z abund. m/ z abund. 28.10 17 56.00 3 78.10 10 119. 10 16 29.10 3 57.10 1 79.10 5 120. 10 3 30.10 3 58.10 1 80.10 4 121. 10 7 37.10 1 61.10 1 89.00 2 122. 10 1 38.10 4 62.00 3 90.10 2 123. 10 1 39.10 14 63.00 7 91.10 7 131. 10 1 40.10 3 64.10 4 92.10 5 132. 10 1 41.20 17 65.00 9 93.10 1 133. 10 2 42.10 33 66.00 3 94.10 1 134. 20 1 43.10 3 67.10 1 98.10 100 145. 10 1
Page 246: nbi31d00
LIBRARY SEARCH RESULTS Scan 876 (18.269 min) of DATA:ACHEA07A.D LIGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CA5 # Library Match Index >< Quality 1: DECANAL 0 1561 8828 2: OCTANE-2,3-DIONE 0 1558 8359 3: HEXANOIC ACID,4-METHYL-S-OXO- 0 1529 7610 4: PYRIDINE,2-METHYL-S-ISOPROPANDL- 0 1587 7440 5: PYRROLE-2-CARBDXAMIDE 0 1567 6976 6: ACRYLIC ACID,3-(2-FURYL)-2-Me-,Et ESTER 0 1533 6933 7: AZETIDINE 0 1128 6928 8: CYCLOHEXANE-1,4-DIONE 0 1566 6519 9: PROPANEDIOL-1,3 0 1627 6448 10: CYCLOPENTANONE,2,5-DIMETHYL- 0 1509 6401 Scan 876 (1B.269 intn) of ORTR:RCHEA07R.0 100` 43 57 71 r100 01 26 II F~1 R1561 OECRNRL 160 1`~ 43 57 62 r100 0J~ 28 1II - I I oiIlll...AAAi a c ro 6 /k1556 ~CTRNE-2.8-OIONE 3 100 `~ rIBO ¢ I2B , I 43 ~ ~ k15E9 HEXANOIC RCI0.4-METHYL-5-QXO- 100~`•.~ ~ 58 96 5 0 '~t..6 43 f/ 74 ~. 0 r--•- 40 60 60 100 Macs/CharBe T: null. Z: TIC of DATA:RCHEAD5R.D GRAPHICSCD Y: TIC of DATA:RCHEAO7R.D [MS2] X: Set of 4 MS Scan 876 (18.269 min) of OATA:ACHEA07A.D LIGHTS-2 m/z abund. m/z abund. m/z abund. m/z abund. 28.15 100 43.15 44 57.05 45 71.15 37 41.25 30
Page 247: nbi31d00
LIBRARY SEARCH RESULTS Scan 880 (18.319 min) of DATA:ACHEA07A.D LIGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: DECANAL 2: PENTADECANAL 3: TRIDECANAL 4: OCTANE-2,3-DIONE 5: UNDECANAL 6: 3-HEXANONE 7: FURANONE-2(3H), 4,5-HYDRO-3,3-DIME-4-HO- 8: HEPTANE-2,5-DIONE 9: FURAN-2-ONE-(3H),4,5-DIHYDRO-3-HYDROXY- 10: CYCLOHEXANONE-1,2-DIDL, 4-METHYL- 1561 7940 1454 7838 1478 7556 1558 7474 1764 7447 469 7446 1647 7293 1530 7094 1525 6961 1660 6953 Bcan 880 (1B.319 mtn) of ORTR!RCHER07R.0 I 3z / y/ , r 160R] 1\B ; 411 I 43 S.I I 11 1®0 01581 OECRNRL 1on 41 43 57 82 100 ~ 0]h6 c m a 01454 PENTRDECRNRL c 1 3 ICi6 \ 67 71 B^c_ 1~0 ¢ B] 2~9 4~1 43 5~ I I ~~ k1476 TRIDECRNRL lo6 t9 \ BB 82 1~0 5 p 'I ,-.--.-----~.!-~-, 4 3 4,. 1 1 1 I~ 0 30 40 50 60 70 BD ._.___MassiCharge GRRPHICSCD tM52I T: null. Z: Scan 876 (18.269 min) of D Y: TIC of DATA:ACHERD7A.D X: Set of 4 MS Scan 880 (18.319 min) of DATA:ACHEA07A.D LIGHTS-2 m/z abund. m/z abund. 28.15 99 39.15 46 29.25 65 32.15 39 41.15 75 m/z abund. m/z abund. 43.25 100 57.15 94 55.05 48 71.05 55
Page 248: nbi31d00
LIBRARY SEARCH RESULTS Scan 1202 (22.420 min) of DATA:ACHEA07A.D LIGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: 3-HEXANONE 0 469 8822 2: PENTADECANAL 0 1454 8717 3: TRIDECANAL 0 1478 8632 4: PYRAN-2-ONE,3,4,5,6-TETRAHYDRD-4-OH- 0 709 8360 5: HYDROCARBON 0 32 8339 6: PYRROLIDIN-2-CARBOXALDEHYOE 0 1474 8096 7: FURANONE-2(3H), 4,5-HYDRO-3,3-OIME-4-HO- 0 1647 8071 8: FURANONE-2(3H), 4,5-HYDRO-3-HYDROXY-3-ME 0 1646 8022 9: NONANAL 0 1434 8004 10: 1,3-DIOXOLAN-2-ONE,4-METHYL- 0 730 7960 Scan 1202 (22.420 m1n) of ORTR:RCHER07R.0 10 100 0 , 29 / BS r I ~ . I~pr 0J I~ i ~ II'3 57 III ;11 ~ c 1o0 ~ 0] I 29 I 1 ~3 I 4j`3 3-HEXRNPNE 71 I, 83 11 k1454 PENTROECRNRL ! 67 71 B2 37~1 10_ 0 p00 `E /71478 TRYOECRNRL 1007 25 ~~ 68 69 82 333 111 ~ ~. 5~ 3 ~7~1 ~ 111_-,1 30 40 50 60 70 B0 Mass/Charga GRRPHICSCD [MS2] 100 [go 90 100 T: null. Z; Scan 88D (18.314 min) of D Y: TIC of DATR;RCHERD7R.D X: Set of 4 MS Scan 1202 (22.420 min) of DATA:ACHEA07A.D LIGHTS-2 m/z abund. m/z abund. m/z abund. m/z a6und. 28.15 25 41.15 62 55.15 29 70.25 10 29.15 45 42.25 23 56.15 22 71.15 54 32.15 13 43.15 99 57.15 100 85.15 33 39.15 16
Page 249: nbi31d00
LIBRARY SEARCH RESULTS Scan 1326 (23.999 min) of DATA:ACHEA07A.D LIGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CRS # Library Match Index # Quality 1: DECANAL 0 1561 8423 2: OCTANE-2,3-DIONE 0 1558 8054 3: HEXANOIC ACID,4-METHYL-S-OXO- 0 1529 7276 4: PYRIDINE,2-METHYL-5-ISOPROPRNOL- 0 1587 6975 5: UNDECANAL 0 1764 6787 6: CYCLOPENTANONE,2,5-DIMETHYL- 0 1509 6778 7: PYRROLE-2-CARBOXAMIDE 0 1567 6616 8: FURANONE-2(3H), 4,5-DIHYORO- 0 1806 6322 9: AZETIDINE 0 1128 6211 10: PYRRDLIDINONE-2 0 1536 6078 Scan 1226 (29.999 mtn) of WRTR:RCHER07R.D 1Ww 0 JI 1"' I I 55 I ('10W 100 1\- JI 28 0 k1561 DECRNRL ~49 57 82 I I iy ~ I 1 M 61558 OCTRNE-2.9-OIONE 100,`~ I_ 71 99 ('100 J 28 43 I~ I l 4A`i 01529 HEXRN6IC RCIW.4-METHYL-5-OXO- 1W0 \ 56 913 100 g0 50 ~ ~ 2R6 ~ I5 l~ 74 126 0 r ~ r J - I ~i -r-- 0 40 GRRPHICSCO [MS2I 60 80 100 120 macc/Charde 1: null. Z: Scan 1303 (23.706 min) of Y: TIC of DATR:RCHER07A.D X: Set of 4 MS Scan 1326 (23.999 min) of DATA:ACHEA07A.D LIGHTS-2 m/z abund. m/z abund. m/z abund. m/z abund. 28.15 100 32.05 63 43.15 41 55.15 48 29.05 48 41.15 54
Page 250: nbi31d00
LIBRARY SEARCH RESULTS Scan 1364 (24.482 min) of DATA:ACHEA07A.D L.I6HTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS 1t Library Index # 1: UNDECANAL 2: OCTADECANOL 3: CYCLOHEXANONE, 4-HYDROXY-2,2,6-TRIMETHYL 4: DECANAL 5: HEXEN-2-AL,TRANS 6: NON-2-ENAL 7: UNDECANOL 8: OCTEN-2-AL,2-PROPYL- 9: HEXEN-2-AL,CIS 10: PENTADECANAL 1764 1818 1717 I561 1441 1448 1765 1452 1440 1454 Scan 1364 (^c4.462 m1n) of ORTR:RCHER07R.0 100 J1 2B I I l51 '19 Bla 00 k1764 UNDECRNRL 100 BS r100 5 [ N '° 01818 6CTROECRNQL ~ 100l 97 11_ 1 ('100 ~ lJ 0~ A d ¢ 0J I 3 lll '1I l3 ~-,~ 01717 CYCLOHEXRNpNE, 4-HYORDXY-2,2.6-TRTMETHYL 100 N A 69 N BB 100 d' 5 i i I I4 1 ~ I7 i 111 i 1, 1-- ° 0 rT-, --r~-- 30 40 50 60 70 60 90 100 110 Mass7Charga GRRPH]CSCD [M527 T: null. Z: Scan 1361 (24.444 min) of V: TIC of DATR:RCHERD7A.0 X: Set of 4 MS Match Quality 7858 7795 7771 7734 7673 7523 7439 7411 7316 7288 Scan 1364 (24.482 min) of OATA:ACHEA07A.D L.IGHTS-2 m/z abund. m/z abund. m/z abund. m/z abund. 28.15 75 41.25 100 55.05 62 69.15 62 29.05 60 43.25 54 57.15 46 83.15 40
Page 251: nbi31d00
LIBRARY SEARCH RESULTS Scan 1555 (26.915 min) of DATA:ACHEA07A.D LIGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS 1: DECANAL 2: UCTANE-2,3-DIONE 3: FURAN-2-ONE-(3H),4,5-DIHYDRO-3-HYDROXY- 4: UNDECANAL 5: AZETIDINE 6: PROPIONALDEHYOE2,2-DIMETHYL- 7: HEXANOIC ACID,4-METHYL-S-OXO- 8: FURANDNE-2(3H), 4,5-HYORD-3-HYDROXY-3-ME 9: PYRAN-2-ONE,3,4,5,6-TETRAHYDRO-4-OH- 10: PENTADECANAL CAS # Librery Match Index # Quality 0 1561 8469 0 1558 7662 0 1525 7174 0 1764 7138 0 1128 6964 0 1462 6901 0 1529 6815 0 1646 6671 0 709 6652 0 1454 6634 5can 1555 (26.915 min) af ORTR:RCHER07R.0 100, r100 0J ~2'7 I 13 l "II"44ii7 100 \~ ] ~26 0 41 01561 DECRNRL 57 / a M155B DCTRNE-2.3-DIDNE C 100 \ ~~ ^ 0.55 r100 ¢ 21 ~ ~~13 ~ ~1 01525 FLIRRN-2-ONE-($H),4,5-DIHYDR0-9-HYDRDXY- N 100 49 1130 50 E9 Be / 7 50 0 30 40 50 60 70 60 90 _ Mast/Char6a T: null. Z: Scan 1551 (26.863 min) of GRRPH]CSCD Y: TIC of DRTR:RCHER07R.D [MS2] X: Set of 4 MS Scan 1555 (26.915 min) of DATA:ACHEA07A,D LIGHTS-2 m/z abund. m/z abund. m/z abund. m/z abund. 28.05 100 32.05 50 43.15 66 57.15 87 29.15 45 41.25 65
Page 252: nbi31d00
LIBRARY SEARCH RESULTS Scan 1907 (31.396 min) of DATA:ACHEA07A.D LIGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS II Library Match Index 4 Quality 1: 2: 3: 4: 5: 6: 7: 8: 9: 10: DECANAL PENTADECANAL UNDECANAL OCTANE-2,3-DIONE TRIDECANAL 3-HEXANONE HEXANOIC ACID,4-METHYL-5-OXO- CYCLOHEXANONE-1,2-DIOL, 4-METHYL- HEX-3-EN-2-ONE,S-METHYL- NONANAL Scan 1907 C31.396 mtnl of ORTR:RCHER07R.0 r~ B I ~1 f 4 9 I~,' 7I1 k1561 DECRNRL 41 49 57 01454 PENTRDECRNRL ~1 42 1 I17 01764 UNDECRNRL 100 \ 50 9 411 -. I 43 I~ 0 I 1 ~ ~ 9Fl 40 50 60 MasaiCharg® GRRPHICSCO [MS27 67 71 82 I I I 1561 7965 1454 7749 1764 7660 1558 7619 1478 7404 469 6899 1529 6853 1660 6803 1604 6711 1434 6610 65 1fd0 50 70 60 T: null. Z: Scan 1900 (31.306 min) of Y: TIC of DRTR:RCHER07R.D X: Set of 4 MS Scan 1907 (31.396 min) of DATA:ACHEA07A.D LIGHTS-2 m/z abund. m/z abund. m/z abund. m/z abund. 28.15 100 32.15 66 43.15 98 57.15 76 29.15 54 41.15 99 55.05 53 71,15 53
Page 253: nbi31d00
LIBRARY SEARCH RESULTS Scan 1367 (24.521 min) of DATA:ACHEA07A.D LIGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: FURANONE-2(3H), 4- ISOPROPYL- 0 1787 8014 2: ISOAMYL ALCOHOL 0 1S00 7978 3: OCT-3-EN-2-ONE 0 1569 7714 4: DECANAL 0 1561 7555 5: UNDECANAL 0 1764 7525 6: UNDECANOL 0 1765 7458 7: OCTANOL-1 0 1546 7435 B: OLEIC ACID, METHYL ESTER 0 1736 7408 9: HEPTANOL-1 0 1548 7355 10: OCTADECANOL 0 1818 7218 Scan 1367 (24.521 mtn) of DRTR:RCHER07R.0 10p ~ ' 70 r100 4 1 5 5./ 0~I ! I II"`000~ /617B7 FLJRRNONE-2(3H), 4- ISOPROPYL- I Zr- 1 ~. ® r ~ 100~I 100 41 I I 55 I 69 t M ~ /015013 ISPRMYL ALCOHOL 3 lpp / r1pp ¢ p~ l 1 4`' I_I I I 55 / I ~ 7 0 l //61569 OCT-3-EN-2-ONE 1003 41 / I 69\ 71 97 111 IP6 100 50~ 55 ' \ J \ ~ ~ ~50 p ~ J ~ „ ~ EEn 40 E0 80 100 120 HaxsiCharDe___.. T: nu11. Z: Scan 1364 (24.482 min) of GRAPHICSCD Y: TIC of DRTA:ACHEA07A.D [MS2] X: Set of 4 MS Scan 1367 (24.521 min) of DATA:ACHEA07A.D I.IGHTS-2 m/z abund. m/z abund. m/z abund. m/z abund. 28.15 88 41.25 92 55.15 100 70.15 43 29.25 57 43.15 75 69.15 41
Page 254: nbi31d00
LIBRARY SEARCH RESULTS Scan 1361 (24.444 min) of DATA:ACHEA07A.D LI6HTS-2 Library fi1e: DRTA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS 1: DECANAL 2: OCTANE-2,3-DIONE 3: HEXANOIC ACID,4-METHYL-5-OXO- 4: CYCLOPENTANONE,2,S-DIMETHYL- 5: PYRIDINE,2-METHYL-5-ISOPROPANOL- 6: OCTAOECANDL 7: OCT-3--EN-2-ONE 8: UNDECANAL 9: HEX-3-EN-2-ONE,S-METHYL- 10: UNDECANOL CRS # Library Match Index II Quality 0 1561 8309 0 1558 7706 0 1629 7310 0 1509 7097 0 1587 6682 0 1818 6570 0 1569 6554 0 1764 6359 0 1S04 6316 0 1765 6315 Scan 1361 (24.444 mtn) of OATR:RCHER67R.0 100~ ~ r100 ( I 5 I I 57 I .l 12 II"0006 6 1&1~,' ' I 26 m 421 III Ik1561 OECR14AL 5,7 106j\ J 1~29 62 I ii /h1556 OCTANE-2,3-OIQNE 139 I 71 !r /k1529 HEXANOIC 10 03 ` ~ 5 0 t.i II E`6---~---~ 4` 3 0 40 GRAPH)CSCO [MS2I T: null. Z: Scan 13;9 (24.419 min) of Y: TIC of DATA:ACHEA07A.D X: Set of 4 MS Scan 1361 (24.444 min) of DATA:ACHEA07A.D LIGHTS-2 m/z abund. m/z ebund. m/z abund. m/z abund. ACI0.4-METHYL-S-OXO- 96 56 7,/4 60 Bm 100 Nass/Charpe u, 28.15 100 41.15 60 55.05 59 69.15 38 ~ 32.15 45 43.15 51 57.15 46 w m
Page 255: nbi31d00
50.15 6 68.15 1 93.15 2 159.15 1 51.15 13 74.05 1 103.15 1 161.15 12 52.15 5 75.05 1 104.15 2 162.15 12 53.05 2 76.15 1 105.15 2 163.15 1 54.05 3 77.15 4
Page 256: nbi31d00
LIBRARY SEARCH RESULTS Scan 1303 (23.706 min) of DATA:ACHEA07A.D L.IGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: OECANAL 0 1561 8098 2: OCTANE-2,3-DIONE 0 1558 7829 3: HEXANOIC ACID,4-h1ETHYL-S-OXO- 0 1529 7106 4: UNDECANAL 0 1764 6901 5: PYRIDINE,2-METHYL-5-ISOPROPANOL- 0 1587 6609 6: CYCLOPENTANONE,2,5-DIMETHYL- 0 1509 6327 7: ISOAMYL. ALCOHOL 0 1500 6169 B: FURANONE-2(3H), 4,5-DIHYDRO- 0 1806 6115 9: PYRROLE-2-CARBOXAMIDE 0 1567 6086 10: AZETIOINE 0 1128 6000 Bcan i303 C23.706 m1n) of ORTR:RCHER07R.0 100J1 12B I I 5 1 r100 ' 0 01581 OECRNRL 1fe0 43 57 82 ~ 26 j 0 1 0 0 "~. I i?\ 1 99 ¢ 0~ ~ I`i 7 '.r'00 r 4 3 ~ lk1529 HEXANOIC 100 \ \` 50 \E6 48 0 40 GRRPHICSCO IMS2I ` 1E0 T: null. Z: Scan 1214 (22.573 min) of Y: TIC of DRTR:RCHER07R.0 X: Set of 4 MS Scan 1303 (23.706 min) of DRTA:ACHEA07A.D LIGHTS-2 m/z abund. m/z abund. m/z abund. m/z abund. 01558 OCTRNE-2.3-DIONE RCI0.4-METHYL-S-OXO- 56 98 / ~li I ^ r ~ 60 60 100 Mass/Charge _ 28.05 100 32.15 73 43.25 50 55.15 59 29.05 63 41.15 56
Page 257: nbi31d00
LIBRARY SEARCH RESULTS Scan 1900 (31.,306 min) of DATA:ACHEA07A.0 LIGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS 1: DECANAL 2: PENTADECANAL 3: OCTANE-2,3-DIDNE 4: TRIDECANAL 5: 3-HEXANONE 6: UNDECANAL 7: FURAN-2-ONE-(3H),4,5-DIHYDRO-3-HYDROXY- 8: HEPTANE-2,5-DIONE 9: HEXANOIC ACID,4-METHYL-S-DXO- 10: FURANONE-2(3H), 4,5-HYDRO-3-HYDROXY-3-ME CAS 7k Library Match Index k Quality 0 1561 8172 0 1454 7586 0 1558 7514 0 1478 7469 0 469 7209 0 1764 7193 0 1S25 7041 0 1530 7034 0 1529 6885 0 1646 6840 9can 190® (31.306 mtn) of ORTR:RCHER07R.0 16~J Y81 14 1 '17 'll r100 ft]0 ~` 41 0~ I6 ~ ~I a c 3 ¢ 161561 OECRNRL 57 il *1454 PENTROECRNRL I ~7 67 82 I '. I I I CCd11' 01558 OCTRNE-2.3-OIONE 6 5 y \ 3 6 10n N 39\ 99 100 .1-.-..-.-. 30 40 50 60 70 80 9m Mass/Char~® T: null. Z: Scan 1555 (26.915 min) of GRAPHICSC6 Y: TIC of DATA:ACHEA07A.D [MS2I X: Set of 4 MS Scan 1900 (31.306 min) of DATA:ACHEA07A,D LIGHTS-2 m/z abund. m/z abund. m/z abund. m/z abund. 28.15 100 32.15 47 43.15 83 57.05 98 29.15 52 41.15 59 55.15 51 71.15 46
Page 258: nbi31d00
LIBRARY SEARCH RESULTS Scan 1551 (26.863 min) of DATA:ACHEA07A.D LIGHTS-2 Library file: DATA:TOBACCO.L Library name; TOBACCO AND SMOKE COMPONENTS CAS R Library Index E 1: • 2 3: 4: 5: 6: 7: 8: 9: 10: DECANAL OCTANE-2,3-DIONE HEXANOIC ACID,4-METHYL-S-OXO- AZETIDINE UNDECANAL PYRIDINE,2-METHYL-S-ISOPRDPANOL- PROPANEDIOL-1,3 FURAN-2-ONE-(3H),4,5-DIHYDRO-3-HYDROXY- PYRROLE-2-CARBOXAMIDE HEX-3-EN-2-DNE,5-METHYL- I561 1558 1529 1128 1764 1587 1627 1525 1567 1504 Scan 1551 (26.863 min) of DRTR:RCHER67R.0 lfie ` r1p0 ~ 2B I I 43 I 57 0 k1581 DECANAL I o 0 \~ u ]~ 26 0 c m ~ c 3 r100 71 ss 28 43 ¢ I~~n 0 ik1529 HEXRNOIC RCIp.4-METHYl.-5-OXO- 1 Ct 0 5 B 9 B 6 F1 0 0 ~ !2 t 5026 43 ~ 74 ~ \ ~'S0 b 40 60 BB 1q0 12B MassiCharge GRRPH]CSCO [MS2] T: null. Z: Scan 1367 (24.521 min) of Y: T1C of DATA:RCHERD7A.D X: Set of 4 MS Match Quality 9394 8410 7666 7346 7208 7195 6763 6503 6406 6385 Scan 1551 (26.863 min) of DATA:ACHEA07A.D LIGHTS-2 m/z abund. m/z abund. m/z abund. M/z abund. 43 57 62 _---~ ~ #1558 OCTRNE-2,3-DIONE 28.15 100 41.15 52 43.25 58 57.05 49 29.15 28
Page 259: nbi31d00
LIBRARY SEARCH RESULTS Scan 1359 (24.419 min) of OATA:ACHEA07A.D LIGHTS-2 Library fi1e: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS 4 Library Index t 1: DECANAL 2: CYCLOPENTANONE,2,5-DIMETHYL- 3: PYRROLE-2-CARBOXAMIDE 4: OCTANE-2,3-DIONE 5: 5: 7: 8: 9: 10: PYRAZINE,2-HYDROXY-3-METHYL- PYRIDINE,2-METHYL-S-ISOPROPANOL- CYCLOHEXANE-1,4-DIONE ACRYLIC ACID,3-(2-FURYL)-2-Me-,Et ESTER HEXANOIC ACID,4-METHYL-S-OXO- 1561 1509 1567 1558 1361 1364 1587 1566 1533 1S29 Scan 195S (24.419 min) of OATR:RCHER07R.0 100 r100 ~5 0~ 6 I 4 II"`0001 01561 OECRNRL 100 ` 41 57 B2 ~100 26 ~ ~I I I i 1/"flfl~ 015133 CYCLOPENTRNONE,2.5-DIMETHYL- 55 69 112 ('10!] I ~ I 4 2 1~033~I 50'~I 26 0 ~l-- k1567 40 / ~ 30 40 50 60 70 60 Mass/Charge GRRPH]CSCO (MS2] 90 100 110 Match Quality 6966 6922 6692 6268 6112 6112 6096 5891 5740 5634 T: null, Z: Scan 1326 (23.999 min) of Y: TIC of DRTA:ACHER07A.D X: Set of 4 MS Scan 1359 (24.419 min) of DATA:ACHEA07A.D LIGHTS-2 m/z abund. m/z abund. 27.45 39 32.15 75 28.25 100 m/z abund. m/z abund. 41.15 53 55.05 61 u, ~ w m 0) J N PYRROLE-2-CRRBOXAHIOE 66 94 110 100 ~ S0 II ~ - M H
Page 260: nbi31d00
LIBRARY SEARCH RESULTS Scan 2102 (33.881 min) of DATA:RCHEA07A.D LIGHTS-2 Library fi1e: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: MENTHOL 2: PHYTOL 3: CYCLOHEXANE-1,2-DIOL,1,3,3-TRIMETHYL- 4: LINALOOL 5: CAMPHOR-D 6: LINOLEIC ACID, METHYL ESTER 7: IONONE,TETRAHYDRO- 8: BICYCLO[440lDECANE,1559-ME-9-HO-10-OXO- 9: MARIOLIDE, DIHYDRO- 10: HEPTANONE-4 Scan 2102 03.881 mfn) of DRTR:RCHER07R.0 132 8625 55 7526 1629 7399 1556 6955 1547 6896 1741 6831 1503 6792 1747 6668 1745 6651 1784 6554 100 109 f 3 ~'100 01I ~.4'Ii~i~ ~lR I 1 '.Tlfi. 100 50 0 43 ~ k132 MENTHOL d h S 123 l5 ~ 1 f ~f ~ ~ 655 PHYTOL r100 4 g~ ~ ~ 12 I'"`9999 #1629 CYCLOHEXRNE-1.2-OIOL.1.3.3-TRIMETHYL- `' 55 4~I~ 40 60 GP,APHICSCD [MS2l 1 BE 60 100 MassiCharBc 1~ 1 1~ 7 I I 120 T: null. Z: Scan 2D72 (33.498 min) of Y: TIC of DATR:ACHER07R.D X: Set of 4 MS Scan 2102 (33.881 min) of DATA:ACHEA07A.0 LIGHTS-2 m/z abund. m/z abu nd, m/z abund. m/ z abund. 28.15 16 45.25 5 68.15 15 83. 15 11 29.15 49 53.15 18 69.15 35 85. 15 9 31.25 11 54.25 12 71 .05 100 95. 15 65 32.05 8 55.15 62 77.15 5 96. 15 24 39.15 36 56.15 28 79.15 7 109. 15 12 41.15 85 57.05 41 80.25 iS 110. 25 8 42.15 15 65.15 5 81.15 77 123. 25 26 43.15 64 67.15 50 82.15 35 138. 25 14 44.15 11
Page 261: nbi31d00
LIBRARY SEARCH RESULTS Scan 6089 (93.484 min) of DATA:EAKEA02R.0 MENTHOL (CONC.) Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS 8 Library Match Index 8 Quality I: 2: 3: 4: 6: 7: 8: 9: 10: NORNICOTINE,N-FORMYL- N-FORMYL NORNICOTINE BIPRIOINE-2,3'-6-ONE,3,4,S,6-TETRAHYDRO- NORNICOTINE,N-BUTYRYL- (SWW 840) NORNICOTINE,N-ACETYL- N-ACETYL NORNICOTINE SH-CYCLOPENTAPYRAZINE,6,7-HYDRD-2-ETHYL- NORNICOTINE NORNICOTINE,N-BUTYRYL- BENZOXAZOLE,C3-ALKYL- (5BB 1530) 761 9742 13 9584 866 0716 337 7174 760 7058 IB 6985 590 6771 1016 6726 1598 6650 618 5796 Scan 6089 (99.4B4 min) oi DRTR:ERKER02R.0 100~ _ 70 107 10B OJIdu.7B~uL,I ~n~ ..d1 I ali, ~AP9 ~~~ 176 ~'H 10B J0 1801 0 N781 NORNICOTINE.N-PDRMYL- 105 { 70 I II I II1I 9 t~ 7 176 I 013 N-FORNYL NORNICOTINE 70 I I 1I05 t~ 9 P7 176 II ('100 /108 R966 BIPRIOINE-E.3'-6-ONE,3.4.7.6-TETRRHYORO- 10B7y 41 79 107 ^ p ~jF10B S0..33 ~ i 7r ~~ I I I 1~I19 11,47 V/6 IPPt[SB 40 BB 80 100 120 140~ 160 NieciCnarB. GRAPHICSCO IMS21 T: null. Z: Soan 5234 (82.528 ein) of Y: TIC ofDATR:EAKEA02R.D X: Sel of 4 MS Scan 6089 (93.484 min) of DATA:EAKEA02A.0 MENTHOL (CONC.) m/z abun d. m/z abund. m/z abund. m/ z abund. ~ 28.10 56 52.10 21 80.00 10 118. 20 24 N w 29.10 34 63.00 10 89.10 5 119. 10 69 m 05 30.20 10 53.90 5 90.10 5 120. 10 36 37.10 4 62.00 7 91.10 15 130. 10 8 ~ m 38.20 12 63.10 17 92.10 29 131. 20 9 N 39.10 40 64.00 li 83.10 22 133. 10 8 40.10 11 65.00 27 98.00 21 145.1 0 4 41.10 37 66.10 6 103.10 4 147.1 0 100 42.10 16 67,00 6 104.10 10 148.1 0 33 43.10 20 68.00 10 105.10 36 159.1 0 /0 44.20 6 70.10 48 106.10 .17 175.1 0 23 45.10 7 77.10 12 107.10 4 176.1 0 68 50.10 18 78.00 22 117.20 12 177.0 0 8 51.10 39 79.00 IB
Page 262: nbi31d00
LIBRARY SEARCH RESULTS Scan 2072 (33.498 min) of DATA:ACHEA07A.D LIGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Index # 1: OCTANE-2,3-DIONE 2: DECANAL 3: HEXANOIC ACID,4-METHYL-5-OXO- 4: PYRIDINE,2-METHYL-S-ISOPROPANOL- 5: CYCLOPENTANONE,2,5-DIMETHYL- 6: OCT-3-EN-2-ONE 7: HEX-3-EN-2-ONE,5-METHYL- 8: PYRROLE-2-CARBOXAMIDE 9: UNDECANAL 10: 1558 1561 1529 1587 1509 1569 1504 1567 1764 1361 Scan 2072 C33.4BB m1n) of ORTR:RCHER07R.0 100 l` _ ~-100 J 12& II 5 ""90001 0 01552 OCTRNE-2.3-0I0NE 100 ~ ~ u D28 C N I 3 1 9 01561 OECRNRL c 100 0 ~ 10 ¢ t6 I I 43 : i 82 ~. 211 c ~ 0 100 S B 98 50~ 28 43 74 ~ / ` i ~~ 0 40 60 80 100 122 _ Mass/CharBe GRRPHICSCO LMS2] Ik152B HEXRNQIC RCI0.4-METHYL-S-OXO- T: nul). Z: Scan 1907 (31.39& min) of Y: TIC of DATA:ACHEA07A.D X: Set of 4 MS Match Quality 8131 7784 7671 6971 6704 6589 6290 6256 6073 5860 Scan 2072 (33.498 min) of DATA:ACHEA07A.D LIGHTS-2 M/Z abund. N/z abund. M/Z abund. M/Z abund. 100 1 26 50 28.15 100 41.15 67 43.25 58 55.05 62 32.15 70
Page 263: nbi31d00
LIBRARY SEARCH RESULTS Scan 2931 (44.475 min) of DATA:ACHEA07A.D LIGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS A 1: NICOTINE 0 2: NICOTINE 0 3: NICOTINE,ISOMER (SL 19D) 0 4: PYRROLIDINE,2-ETHYL-1-METHYL- 1 5: PYRROLIDINE,I-PROPYL- 1 6: ANABASINE 0 7: PIPERIDINE,2-ETHYL- 0 8: PYRROLIDINE,1-ETHYL- 1 9: GLUTARIMIDE,3-METHOXY- 0 10: PYRROLIDINE,2,S-DIMETHYL- I Scan 2931 100, 4Z }I 65 0 . .~.i~„ .i.... ~... 4 / 2 4/ 2 I (44.475 mtn) of ORTR:RCHER07R.0 16119 133 161 07 NICOTINE I\ 119 ~ g 161 24 i { 1 6238 NICOTINE I B 4 1/ 9~,. 9 kB74 NICOTINE.ISOMER 4 / 2 40 60 B0 100 120 140 Mass/Charpa GRRPHICSCU [MS27 1~ 1 1 Library Match Index t Quality 7 9948 236 9948 874 8995 1156 8801 1155 8563 498 8428 1137 8198 1150 8156 767 8151 1151 8024 i00 (9L 190) 175 204 100 \\~"id 0 160 160 200 T:null. Z: Soan 2927 (44.424 min) of Y: TIC of DATR:RCHERD7A.D X: Set of 4 KS Scan 2931 (44.475 min) of DATA:ACHEA07A.0 LIGHTS-2 m/z abund. m/z abund. m/z abund. m/ z abund. 28.15 14 50.15 4 67.05 2 104. 15 3 29.15 3 51.15 11 77.15 5 105. 15 3 30.15 2 52.15 4 78.15 7 117. 1S 5 32.05 3 54.15 3 79.15 3 118. 25 7 38.15 4 55.05 B 81.15 2 119. 15 9 39.15 12 56.15 3 82.15 8 130. 15 5 40.15 2 63.15 7 84.15 100 133. 15 32 41.25 12 64.15 3 85.15 6 134. 15 4 42.15 33 65.05 8 91.15 4 161. 15 16 43.15 4 66.05 2 92.15 8 162. 15 15 55 I~ / L94
Page 264: nbi31d00
LIBRARY SEARCH RESULTS Scan 2927 (44.424 min) of DATA:ACHEA07A.D LIGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS 1: NICDTINE CAS # 0 Library Index # 7 Match Quality 9922 2: NICOTINE 0 236 9922 3: NICOTINE,ISOMER (SL 19D) 0 874 8941 4: PYRROLIDINE,2-ETHYL-I-METHYL- I 1156 8697 5: PYRROLIDINE,1-PROPYL- I 11s5 8497 6: ANABASINE 0 498 8421 7: PIPERIDINE,2-ETHYL- 0 1137 8166 8: GLUTARIMIDE,3-METHOXY- 0 767 8119 9: PYRROLIDINE,1-ETHYL- I 1150 8093 10: PYRROLIDINE,2,5-DIMETHYL- t 1161 7960 100 Scan 2927 (44.424 m1n) of ORTR:ACHER07R.0 ' 42 55 119 133 161 100 1 100 07 NICOTINE 1 4 2 \ 1 9 133 1 1 (100 a u C JI0 / 1 ~ ~ m ~ 022E NICOTINE c 100 D , 4 / 2 \ "... 1%9 3 161 I r100 ¢ Jo I 6 4 1 , I. J u I `.00 8674 NICOTINE.ISOMER (SL 190) 100 100 55 175 2® p € 50 / r 64 \ ~ 50 k 0 ~ ~L/ "- - ~ ; ~ ~ i . 40 60 60 100 120 140 160 160 200 MassiCharge GRAPHICSCO [MS27 T: null. Z: Scan 2899 (44.057 min) of Y: TIC of DRTA:ACHEA07A.D X: Set of 4 MS Scan 2927 (44.424 min) of DATA:ACHEA07A.0 LIGHTS-2 m/z ab und. m/z abund. m/z abund. m/ z abund. 28.15 14 50.25 4 66.15 2 104. 25 2 29.15 4 51.15 12 67.05 3 105. 15 3 30.15 3 52.15 6 76.15 2 117. 15 4 32.15 3 53.15 3 77.15 5 118. 25 6 38.15 3 54.15 3 78.05 6 119. 15 10 39.15 10 55.15 9 79.15 3 120. 15 2 40.15 2 56.05 3 82.15 7 130. 15 5 41.15 10 57.15 3 84.15 100 133. 15 32 42.15 32 63.05 6 85.15 6 134. 15 4 43.15 S 64.05 3 91.15 4 161. 15 18 4 4.15 4 65.05 R A7.1S 7 1R9_ iS 1F
Page 265: nbi31d00
LIBRARY SEARCH RESULTS Scan 2886 (43.B85 min) of DATA:ACHEA07A.D LIGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality Ic NICOTINE 2: NICOTINE 3: NICOTINE,ISOMER (SL 190) 4: PYRROLIDINE,1-PROPYL- 5: PYRROLIOINE,2-ETHYL-I-METHYL- 6: PYRROLIDINE,1-ETHYL- 7: ANABASINE 8: PYRROLIDINE,2,5-OIMETHYL- 9: PIPERIDINE,2-ETHYL- 10: GLUTARIMIDE,3-METHOXY- 7 9817 236 9817 874 9062 1155 8719 1156 8690 1150 8304 498 8226 1151 8177 1137 8159 767 8113 Scan 2686 (43.685 mtn) of ORTR:RCHER07R.0 100 nl 4E 65 I 119 133 161 t00 . .a.i.. .i..,... ...... ..,. .... B4. ..... ~ ..l . .ii \ 07 NICOTINE 19119 f 3 161 84 , \ Y36 NICOTINE 119 133 161 (100 84 / ~, I '9i 4 / 2 1 kB74 NICOTINE..ISOMER (SL 190) 100 55 ~ 175 p0~4 ~~1~00 50~ ~~ / 84 ~ \ {'S0 ® Y` ~'t r~ r ~~ 40 s0 60 100 120 140 160 180 200 Mass/Charga GRRPH]CSCO [M52J T: null. Z: Scan 2102 (33.881 min) of Y: TIC of DRTR:RCHER07R,D X: Set of 4 MS Scan 2886 (43.885 min) of OATA:ACHEA07A.D L.IGHT5-2 m/z abund. m/z abund. m/z abund. m/ z abund. 28.15 11 54.15 3 78.05 7 106. 15 1 29.15 2 55.15 6 79.15 2 107. 25 1 30.15 2 56.15 1 80.15 2 117. 15 4 37.25 1 57,15 1 81.15 2 118. 15 6 38.15 3 62.15 2 82.15 6 119. 15 9 39.15 13 63.05 6 84.15 100 120. 15 2 40.25 3 64.15 3 85.15 6 130. 15 4 41.25 10 65.05 8 89.15 1 131. 15 1 42.15 39 66.05 2 90.15 1 133. 15 28 43.15 3 67.15 2 91.15 4 134. 25 3 44.15 3 68.15 1 92.15 7 145. 25 I
Page 266: nbi31d00
LIBRARY SEARCH RESULTS Scan 4294 (61.881 min) of DATA:ACHEA07A.D LIGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: BETA-NICOTYRINE 0 536 7718 2: PYRIDINE,2-(N-METHYLPYRROL-2-YL) 0 291 7530 3: QUINOXALINE,DIMETHYL- (SBB 174) 0 609 7286 4: UNKNOWN (NICOTINE LIKE) (SWW 206D) 0 349 6756 5: PYRIDINE,3-(2-METHYL-I-PYRROLYL)- 0 1011 6226 6: PYRROLE,N-(2-PYRIDYLMETHYL)- 0 1590 6174 7: QUINOXALINE,2-ETHYL- 0 1125 6154 8: CYCLOPENTANONE,2,5-DIMETHYL- 0 1509 5345 9: PYRROLE-2-CARBOXAMIDE 0 1567 5134 10: ISOMER OF SR238C (LIB ENTRY #33) 0 1591 5019 Scan 4294 (61.B81 iw 0 min) of ORTRfRCHER07R.0 1 I I 80 ~/'~r100 0~26 1 156 ILOI I k536 BETR-NICOTYRINE 130 (100 I 42 79 90 117 ` 6~ 158 ~ fl u /"`000 c m B 0291 PYRIDINE.2-(N-METHYLPYRROL-2-YL) 100 3 39 BS 7~ 00 ¢ 0] / I ~i 7~30 15B 11L 100 50 0 k609 QUINOXRLINE.DIMETHYL- (566 174) ~/FFt 100 39 65 78 130 !56 ~'S0 / \ 11 'f'~rool 40 60 60 100 120 140 Mass/Charpe T: null. Z: Scan 3964 (57.656 min) of GRRPHICSCD Y: TIC of DATR:ACHEAD7R.D IMS2I X: Set of 4 MS Scan 4294 (61.861 min) of DATA:ACHEA07A.D LIGHTS-2 m/z ebund. m/z abund. m/z abund. m/z abund. 28.15 80 42.15 34 157.15 52 158.05 100 32.05 34 130.15 37
Page 267: nbi31d00
LIBRARY SEARCH RESULTS Scan 3474 (51.397 min) of DATA:ACHEA07A.0 LIGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: OCTANE-2,3-DIONE 2: DECANAL 3: HEXANOIC ACID,4-METHYL-S-OXO- 4: PYRIDINE,2-METHYL-5-ISOPROPANOL- 5: PYRROLE-2-CARBOXAMIDE 6: CYCLOPENTANONE,2,5-OIMETHYL- 7: ACRYLIC ACID,3-(2-FURYL)-2-Me-,Et ESTER 8: AZETIDINE 9: OXAZOLIDINE-2,4-DIONE,S-METHYL- 10: PYRROLIDINONE-2 I too Scan 3474 (51.397 min) nP QRTR!RCHEA07R.0 Ian Igo 1311 128 1 1 43 J 28 43 , I 120 1~1~ oil ?B #1558 OCTRNE-2,3-DIONE 71 99 I I I 01561 13ECRNRL 4 S 57 82 01528 HEXRNOIC 5 0 L2~8 4S 413 GRAPHICSCD [11S21 AC1D.4-METHYL-5-0X0- a 74 Matt /Charp a 126 F1,11, 120 1558 9170 1561 8758 IS29 8256 1587 8207 1567 7651 1509 6946 1533 6916 1128 6817 1725 6581 1536 6397 q 13 T: null. Z; Scan 2931 (44,475 min) of Y; TIC of DATA:RCHERWAX X: Set of 4 110 Scan 3474 (51.397 min) of DATA:ACHEA07A.D LIGHTS-2 m/z abund. m/z abund. z m/z abund. m/z abund. 28.15 100 32.15 47 41.2S 32 43.16 46 29.2S 31
Page 268: nbi31d00
LIBRARY SEARCH RESULTS Scan 3948 (57.452 min) of DATA:ACHEA07A.D LIGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: MYOSMINE 0 10 9733 2: PYRROLE[1,2a)PYRAZINE,3,6-DIMETHYL- 0 1371 7411 3: BENZONITRILE,2-AMINO- 0 1488 6879 4: NORNICTINE,1-NITROSO- 0 1013 6761 5: PYRIDINE,2-(1-PROPENYL)- (5BB 236D) 0 543 6853 6: BENZIMIDAZOLE 0 95 6608 7: TETRALONE-1 0 834 6508 8: IMIDAZO[1,2a]PYRIDINE 0 968 6474 9: BENZIMIDRZOLE 0 614 6467 10: IMIDAZO[1,2-a]PYRIDINE,2,3-DIMETHYL- 0 924 6417 5can 3948 (57.452 m1n) of ORTR:RCHER07R.0 EB 51 78 131 1 i dJi d m i1 ~ ,I 116 146 II R10 MYOSMINE s 148 II 01971 PYRROLECi.Pa]PYRRZINE.9.6-OIMETHYL- 1©07 39_ 51 104 116 fr 100 0J I i 1j ~ I146 III /k14B6 BENZONITRILE.B-RMINO- 100 63 /64 100 56~^ `/ B1 36 ~00 0 20 40 60 80 100 120 140 MassiCharm® T: null. Z: Scan 3946 (57.425 min) of GRRF'H]CSCD Y: T]C of DflTR:RCHEA07R.D [MS2] X: Set of 4 MS Scan 3948 (57.452 min) of DATA:ACHEA07A.D LIGHTS-2 m/z abund. m/z abund. m/z abund. m/z abund. 28.15 31 42.15 19 65.05 15 105.15 21 32.05 14 50.15 11 77.15 12 118.15 100 38.25 12 51.15 27 78.05 29 119.15 13 39.15 26 63.05 16 91.15 14 145.15 62 40.15 9 63.95 11 104.15 12 146.15 65 41.15 28
Page 269: nbi31d00
LIBRARY SEARCH RESULTS Scan 3964 (57.656 min) of DATA:ACHEA07A.D L.IGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS 1: MYOSMINE 2: PYRROLE[1,2alPYRAZINE,3,6-DIMETHYL- 3: TETRALONE-1 4: BENZONITRILE,2-Ah1IN0- 5: NORNICTINE,1-NITROSO- 6: CYCLOPENTAPYRIZINE-5H,2,3-DIMETHYL- 7: BENZIMIOAZDLE,C2-ALKYL- (SWW 610) 8: BENZIMIDAZOLE 9: PYRIDINE,2-(1-PROPENYL)- (SBB 2360) 10: IMIDAZO[I,2-aIPYRIDINE,2,3-DIMETHYL- Sc an 3964 (57.656 m1n) of 01 1111 51 CAS II Library Match Index tt Quality 0 10 8830 0 1371 6784 0 834 6100 0 1488 6077 0 1013 6058 0 1104 5858 0 908 5786 0 95 5758 0 543 5755 0 924 5753 ORTR:RCHER07R.0 76 /P10 MYOSMINE 51 76 105 i I ~ I 11 11 146 11 B f-~ 146 I M N1371 PYRROLEC1.Ea7PYRRZINE.9,6-OIMETHYL- 3 9 5 1 104 1,1 B ~i i I I I ,rr100 46 ~I 1 08214 TETRRLONE-1 1003 39 B3 100 50~ ~ ~ ~0 4'is 14 I~50 0 P0 40 60 60 100 120 140 MassiChargQ T: null. Z: Scan 3948 (57.452 min) of GRRPH1CSCh Y: TIC of DATA:ACHER07A.D [MS2l X: Set of 4 MS Scan 3964 (57.656 min) of DATA:ACHEA07A.D LIGHTS-2 m/z abund. m/z abund. m/z abund. m/z abund. 28.15 49 41.15 30 51.15 34 118.15 100 32.05 22 42.15 27 78.05 32 145.25 49 38.25 19 50.25 22 105.15 25 146.15 74 39.15 25
Page 270: nbi31d00
LIBRARY SEARCH RESULTS Scan 1904 (31.360 min) of OATA:ACHEAOBA.D REGULAR-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS 1: PENTADECANAL 2: 3-HEXANONE 3: TRIDECANAL 4: PYRAN-2-ONE,3,4,5,6-TETRAHYDRO-4-OH- 5: HYDROCARBON 6: HEPTANAL 7: NONANAL 8: HEPTANE-2,5-DIONE 9: FURANONE-2(3H), 4,5-HYORO-3-HYDROXY-3-ME 10: 1,3-OIOXOLAN-2-ONE,4-METHYL- CAS # Library Match Index # Quality 0 1454 8490 0 469 8462 0 1478 8348 0 709 8173 0 32 7957 0 1433 7866 0 1434 7823 0 1530 7770 0 1646 7755 0 730 7730 Scar, 19134 (31.360 mtn) of ORTR:RCHER68R.0 td0J~l2~ I113 5 I 71 ' 85 ('10e 1470 ~ B~ I 29 n ¢ I 4h3 01454 PENTROECRNAL / 67 71 B2 57 111 1 1 ( 0469 3-HEXRNONE 71 1013 r 100 .e 01478 TRIOECRNAL 1©p 29 ~~,` I 6B_ 69 82 F10PJ 51~ '~ 4I3 5711 L 11 1 r ~50 0"'3,-+I,-----^ i i i ~ --i -^-^--+-...--i 6 30 40 513 E13 72 Bfd 90 102 _ Mass/Charge T: null. Z: Scan 1901 (31.322 min) of GRAPHICSCO Y: TIC of DATA:ACHEA08A.D 1MS2I X: Set of 4 MS Scan 1904 (31.360 min) of OATA:ACHEA08A.D REGULAR-2 m/z abund. m/z abund. m/z abund. m/z abund. 28.15 49 41.15 67 55.15 37 71.15 45 29.15 45 42.25 24 57.15 98 85.15 34 32.15 23 43.15 100 70.25 17
Page 271: nbi31d00
LIBRARY SEARCH RESULTS Scan 3946 (57.425 m1n) of DATA:ACHEA07A.D LIGHTS-2 Library file: DATR:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: MYOSMINE 0 10 9239 2: PYRROLE[1,2a]PYRAZINE,3,6-DIMETHYL- 0 1371 7211 3: NORNICTINE,1-NITROSO- 0 1013 6377 4: BENZONITRILE,2-AMINO- 0 1488 6299 5: TETRALDNE-1 0 834 6206 6: PYRIDINE,2-(1-PROPENYL)- (SBB 236D) 0 543 6135 7: CYCLOPENTAPYRIZINE-SH,2,3-DIMETHYL- 0 1104 6094 8: IMIDAZO[1,2-a)PYRIDINE,2,3-DIMETHYL- 0 924 6074 9: BENZIMIDAZOLE,2-ETHYL- 0 1180 S990 10: BENZIMIDAZOLE 0 95 6969 Scan 394E C97.425 26 51 ~ ~ ili~l 11 ill m1n) of ORTR:RCHER07R.0 7a I il 11 18 14611 tk10 MYOSMINE 51 78 ~.... I I 1 i1 8 14611 100 a R1371 PYRROLEC1.2a7PYRRZINE,3,6-DIMETHYL- 3 100 39 51 i/1B /1 r100 ¢ 0~ I i ~ 1 I 146 I~ k1013 NORNICTINE,1-NITRO50- 100 41 51 76 147 177 ~100 5 0~ I ''"r I I I 1 0~ I ~"5 0 B ' ~r 0 20 40 60 B0 102 1F0 140 160 _ Mass/Charge T: null. Z: Scan 3474 (51.397 min) of GRRPHICSCD Y: TIC cf DRTA:ACHEAD7A.D [MS2) X: Set of 4 MS Scan 3946 (57,425 min) of DATA:ACHEA07A.D LIGHTS-2 m/z abund. m/z abund. m/z abund. m/z abund. 28.05 40 42.25 17 65.05 32,05 12 50.05 17 77.05 38.15 13 51.15 24 78.05 39.15 27 63.05 13 104.15 40.15 12 64.05 14 105.15 14 117.15 17 13 118.15 100 27 119.15 9 12 145,25 59 24 146.15 70 41.25 34
Page 272: nbi31d00
50.15 5 69.15 1 93.15 2 159.15 1 51.15 13 75.15 1 103.15 1 161.15 13 52.15 5 76.16 1 104.15 2 162.15 12 53.05 2 77.16 4 105.15 2 163.15 2 LIBRARY SEARCH RESULTS Scan 2899 (44.057 min) of DATA:ACHEA07A.0 LIGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS It Library Match Index k Quality 1: NICOTINE 0 7 9802 2: NICOTINE 0 236 9802 3: NICOTINE,ISOMER (SL 19D) 0 874 9088 4: PYRROLIDINE,1-PROPYL- 1 1155 8722 5: PYRROLIDINE,2-ETHYL-I-METHYL- 1 1156 8693 6: PYRROLIDINE,1-ETHYL- 1 1150 8308 7: ANABASINE 0 498 8201 8: PYRROLIDINE,2,5-DIMETHYL- 1 1151 8180 9: PIPERIDINE,2-ETHYL- 0 1137 8162 10: GLUTARIMIDE,3-METHOXY- 0 767 8115 Scan 2899 (44.057 mtn) Df oRTA:ACHEA07R.0 42 65 \ 119 133 162 f100 u N c n 100 501 2 4 / 1 42 / Ik7 NICOTINE \ 119 „r3g 161 r100 94 / / 296 NICDTINE \ I64 1/ 9 ,~,...3 ii , N674 NICOTINE.ISONER 42 55 161 II SSL 190) 175 E04 100 ~ ~50 40 60 60 100 120 140 16 0 160 200 _ HassiChhrOB T: null. Z: Scan 2886 (43.885 mie) of GP,APH]CSCD Y: TIC of DATA:RCHEA07A.D [MS2] X1 Set of 4 MS Scan 2899 (44.057 min) of DATA:ACHEA07A.D LIGHTS-2 m/z abund. m/z abund. m/z abund. m/ z abund. 28.15 11 55.15 6 78.05 6 106. 15 2 29.15 2 56.15 1 79.15 2 107. 15 1 30.15 2 57,15 1 80.15 2 117. 15 4 37.15 1 58.15 1 81.15 2 118. 15 6 38.15 3 59.55 I 82.15 7 119. 15 8 39.15 13 62.15 2 84.15 100 120. 15 2 40.25 3 63.05 6 85.15 5 130. 15 4 41.25 10 64.15 3 89.15 1 131. 15 1 42.15 39 65.16 9 90.15 1 133. 15 28 43.15 2 66.05 2 91.15 4 134. 15 3
Page 273: nbi31d00
LIBRARY SEARCH RESULTS Scan 4297 (61.899 min) of DATA:ACHEA07A.D LIGHTS-2 Library file: DATA:TOBRCCO.L Library name: TOBACCO AND SMOKE COMPONENTS 1: PYRIDINE,2-(N-METHYLPYRROL-2-YL) 2: BETA-NICOTYRINE 3: QUINOXALINE,DIMETHYL- (SBB 174) 4: UNKNOWN (NICOTINE LIKE) (SWW 206D) 5: PYRIDINE,3-(2-METHYL-I-PYRROLYL)- 6: PYRROLE,N-(2-PYRIDYLMETHYL)- 7: QUINOXALINE,2-ETHYL- 8: PYRROLE-2-CARBOXAMIDE 9: ACRYLIC ACI0,3-(2-FURYL)-2-Me-,Et ESTER 10: ISOMER OF SR238C (LIB ENTRY #33) 10 63 CAS # Library Match Index # Quality 0 291 7453 0 536 7406 0 609 7156 0 349 6663 0 1011 6101 0 1590 6078 0 1125 5976 0 1567 5384 0 1533 5351 0 1591 5244 ORTR:RCHER07R.0 i30 ~ BIr100 15 ~i k251 PYRIOINE.S.-(N-METHYLPYRROL.-2-YL) 100, 65 ~ 00 m u m J 0 39 I ~ 79 .~ / i Q 0 58 I II"`0001 a M536 BETR-NICOTYRINE c 100 / r100 a 42 79 90 117 130 1 I a Jo i i u iI / I 158 444~~~~ ~6 09 OtJINOY:RLINE, DIMETHYL- (5B6 174) 00 100 65 ~ 50 39 78 \ 130 158 50 / / \ / 0 , - ~- ----.-T: Jul 0 40 60 0 100 120 140 Mass/Charge GRAPH]CSCU [MS2I T: null. Z: Scan 4294 (61.861 min) of Y: TIC of DATA:RCHEA07A.D X: Set of 4 MS Scan 4297 (61.899 min) of DATA:ACHEA07A.D LIGHTS-2 m/z abund. m/z abund. M/z abund. m/z abund. Scan 4297 C61.699 mtn7 oF 28.15 90 130.15 33 157.05 47 158.15 100 63.15 26
Page 274: nbi31d00
LIBRARY SEARCH RESULTS Scan 5961 (83.095 min) of DATA:ACHEA07A.D LIGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS ' CAS # Library Match Index # Quality 1: COTININE 0 12 9747 2: N-METHYL ANABASINE (SWW 20) 0 237 8982 3: PIPERIDINE,1-ETHYL- 0 1136 8720 4: 1,5-DIMETHYL-2-PYRROLIDINONE 0 40 8596 5: PYRROLIOIN-2-ONE,1,5-DIMETHYL- 0 1378 8588 6: NORNICOTINE,N-ETHYL- (SL 3901 0 878 8244 7: PYRIDINE,3-(I-ET-2-PYRROLIDINYL)- 0 999 8172 8: PIPERIDINE,1-METHYL- 1 1143 7446 9: PIPERIDINE,2,3-DIMETHYL- 1 1139 7241 10: 2-PIPERIDONE,6-METHYL- 0 787 7105 Scan 5961 (83.095 mtn) of ORTR:RCHER07R.0 42 51 ~ ilg 147 178 r100 #lE COTIN~/INE 42 / 11B I / 9B li, N257 N-HETHYL RNRBRSINE C9WW 20) 42 70 1l1 9 1 r 96I : #1136 PIPERIOINE.1-ETHYL- 100 50 42 96 112 ! 0 i i1 i r r 11 0 20 40 60 60 100 120 140 160 Mass/CharR® __ d 100 50 T: null. Z: Scan 4670 (66.648 min) of GRRPHICSCO Y: TIC of DATA:RCHER07A.0 [MS21 X: Set of 4 MS Scan 5961 (83.095 min) of DATR:ACHEA07A.D LIGHTS-2 m/z abund. m/z abund. m/z abund. m/ z abund. 28.15 27 52.15 6 78.05 10 118. 15 13 29.05 5 55.05 6 79.15 6 119. 15 16 38.25 7 63.15 7 91.05 7 121. 25 9 39.15 17 64.05 6 92.15 5 147. 15 7 41.15 19 65.15 8 98.15 100 175. 15 13 42.15 35 68.15 7 99.05 6 176. 15 36 50.15 9 69.15 9 117.25 6 177. 15 5 51.15 13 70.05 7 147 176 N-1 -...'_
Page 275: nbi31d00
51.15 4 72.15 6 53.05 17 73.15 1 LIBRARY SEARCH RESULTS Scan 2821 (43.048 min) of DATA:ACHEA08A.D REGUL.AR-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS 1: OCTADECANOL 2: UNDECANOL 3: GERANIOL, TETRAHYDRO- 4: NONYL ALCOHOL 5: GERANIOL, TETRAHYORO- 6: FURANONE-2(3H), 4- ISOPROPYL- 7: OCTANOL-1 8: HEPTANOL-1 9: NONANAL 10: OCTEN-2-AL,2-PROPYL- CAS # Library Match Index # Quality 0 1816 9524 0 1765 9501 0 1795 9149 0 1771 8893 0 1781 8850 0 1787 8757 0 1546 8718 0 1548 8359 0 1434 8350 0 1452 8311 Bcan EBES (43.046 m1n) of ORTR:RCHER0BR.0 10m'~I f9 ~3 ,~I `7i '13 9 i rlee *1818 OCTROECRNOL m u c a C a ~, 13 lll ll l3 g~ M1765 (JNOECRNOL 1 I 1 4 lI ~3 9• ; R1795 GERRNIOL. TETRRHYDRO- 100 3 5~~ IM - - -- - - - - r r , ~ . r 304 D ----5--r-0 - GRAPHICSCO [M;27 93.15 5 139.25 2 95.15 66 T: null. I: Scan 2106 (33.941 min) of Y: TIC of DATA:RCHEADBA.D X: Set of 4 MS Scan 2821 (43.048 min) of DATA:ACHEA06A.0 REGULAR-2 m/z abund. m/z abund. m/z abund. m/z abund. 97 100 84 u\ n0 / ~ 50 II II I 60 70 B0 90 100 110 MassiCharge 28.15 46 41.15 98 56.15 41 70.05 46 29.15 49 43.15 100 57.15 37 83.15 53 32.15 28 55.05 90 69.15 71 97.15 33
Page 276: nbi31d00
LIBRARY SEARCH RESULTS Scan 4670 (66.648 min) of DATA:ACHEA07A.D LIGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS I: BENZOPHENONE 2: BENZOIC ACID, METYL ESTER 3: PROPIOPHENONE 4: BENZIL 5: BENZOIC ACID, ETHYL ESTER 6: ACETOPHENONE 7: PHTHALIDE e: BENZAMIDE 9: BENZYALDEHYDE 10: BENZYL BENZOATE CAS # Library Index # Match Quality 0 1798 8931 0 1544 7721 0 176 7665 0 802 7593 0 1543 7542 0 440 7471 0 54 7256 0 181 6814 0 57 6704 0 47 6646 Scar. 4870 C66.648 mfn) of DRTR:RCHER07R.0 100 ~ -`-~_ ~ ••J! 100 0 26 1 1 51 ( 77 05 182 I 01798 BENZOPHENONE 1001 50 00 m I 5 1 I 7 7 1~0 5 152 2 182 u J 0 II I m ~ M1 544 BENZOI C RCID METYL ESTER c 100, . 00 n 50 51 ~ 196 ¢ J0 L 0178 P ROPIQPH ENONE 100 100 3 50 51 77 134 ~ 50~ 05 \ _0 , 0 . i 40 6 0 80 100 120 140 160 160 MnssiCharge GRAPHICSCO CMS2] T: null. Z: Scan 4297 (61.899 min) of Y: TIC of DRTA:RCHEA07A.D X: Set of 4 MS Scan 4670 (66.648 min) of DATA:ACHER07A.D LIGHTS-2 m/z abund. m/z abund. n/z abund. m/z abund. 28.15 64 50.15 27 77.05 78 182.15 74 32.05 32 51.15 54 105.15 100
Page 277: nbi31d00
50.15 5 68.05 1 92.15 8 147.15 1 51.15 13 69.05 1 93.15 2 159.15 1 52.15 5 74.05 1 103.15 1 161.15 13 53.15 2 75.05 1 104.15 2 162.15 12 54.05 3 76.05 1 105.15 2 163.15 1
Page 278: nbi31d00
LIBRARY SEARCH RESULTS Scan 1901 (31.322 min) of DATA:ACHEA08A.D REGULAR-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: 3-HEXANONE 0 469 8473 2: PENTADECANAL 0 1454 8428 3: TRIDECANAL 0 1478 8319 4: UNDECANAL 0 1764 7942 5: HYDROCARBON 0 32 7941 6: PYRAN-2-ONE,3,4,5,6-TETRAHYDRO-4-OH- 0 709 7906 7: NONANAL 0 1434 7778 8: ACETAMIDE,N-ALLYL- 0 747 7724 9: FURANONE-2(3H), 4,5-HYDRO-3,3-DIME-4-HO- 0 1647 7724 10: FURAN-2-ONE(3H),4,5-DIHYDRO-3,4,4-METHYL 0 1659 7724 Scan 1901 (91.32G min) of DRTR:RCHER0BA.0 100 65 r100 0J 5 I 'll i ~ C 160 ~ Q I 29 0 113 I ~3 8469 3-HEXRNDNE r 57 N1454 PENTRDECRNRL I 67 71 62 5711~ `I I --' I 100 `fl k1476 TRIOECRNRL 10,'~~ 29 ~ BB_ 69 B2 00 FE1~d I 413 37I I f30 0 30 40 50 60 70 913 90 100 ~ Mass/Charps T: null. Z: Scan 1772 (29.677 min) of GRAPH)CSCq Y: TIC of DATA:ACHEAD8A.D [MS2] X: Set of 4 MS Scan 1901 (31.322 min) of DATA:ACHEA08A.D REGULAR-2 m/z abund. m/z abund. m/z abund. m/z abund. 28.15 47 41.15 64 55.16 31 71.15 52 29.15 35 42.25 26 56.15 29 85.15 37 32.15 25 43.25 100 57.05 82
Page 279: nbi31d00
50.15 6 69.05 1 92.15 7 159.15 1 51.15 14 74.05 1 93.15 2 161.15 12 52.15 5 75.15 1 103.15 1 162.16 11 53.15 2 76.15 1 104.15 2 163.15 1 54.15 3
Page 280: nbi31d00
LIBRARY SEARCH RESULTS Scan 1197 (22.354 min) of DATA:ACHEA08A.0 REGULAR-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: 3--HEXANONE 0 469 8887 2: PENTADECANAL 0 1454 8807 3: TRIDECANAL 0 1478 8733 4: PYRAN-2-ONE,3,4,5,6-TETRAHYDRO-4-OH- 0 709 8381 5: HYDROCARBON 0 32 8237 6: NONANAL 0 1434 8190 7: FURANONE-2(3H), 4,5-HYDRO-3,3-DIME-4-HO- 0 1647 8089 8: PYRROLIDIN-2-CARBOXALDEHYDE 0 1474 8022 9: ACETAMIDE,N-ALLYL- 0 747 7968 10: CYCLOHEXANONE-1,2-DIOL, 4-METHYL- 0 1660 7954 5can 1197 [22.354 m1n) of ORTA:RCHER06R.p 100l 00 I 29 ~ ~ 85 1 OJI~~ i li3 57III ~fll ~ #469 3-HEXRNONE . 57 ~. 71 11 63 #1454 PENTRDECRNRL 67 71 62 / I 29 I 3 57IiI --t f I 100 29 5m~~ ^ 0 #1476 TRIOECRNRL ~ 66 69 82 919 3 7 ~ I~`~ .^'~ I 10..!~ L0 30 40 50 60 70 90 90 100 1laxsiCharge T: null. Z: TIC of DATA:RCHEAD7A.D GRRPHICSCO Y: TIC of DATA:RCHERDBA.D [MS2] X: Set of 4 MS Scan 1197 (22.354 min) of DATA:ACHEA08A.D REGULAR-2 m/z abund. m/z abund. m/z abund. m/z abund. 28.15 27 41.15 75 56.25 23 71.15 55 29.15 38 42.25 19 57.15 98 84.25 8 32.15 11 43.15 100 69.15 11 85.15 32 39.15 17 55.15 28 70.15 13
Page 281: nbi31d00
LIBRARY SEARCH RESULTS Scan 1962 (32.100 min) of DATA:ACHEA08A.D REGULAR-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS k Library Match Index ik Quality 1: BETA-IONOL 0 58 6027 2: PYRAZINE,iso-PROPENYL- 0 1118 5374 3: PARA-CYMENE 0 226 5332 4: BENZONITRILE,4-HYOROXY- 0 1596 5319 5: BENZALDEHYDE,4-ISOPROPYL- 0 1408 5210 6: CYCLOPENTAPYRIZINE-5H,6,7-DIHYDRO- 0 1105 5165 7: BENZALDEHYDE,Z-METHYL- 0 1405 5134 8: BENZALDEHYDE,3-METHYL- 0 1406 5102 9: ACETONITRILE 0 1480 5088 10: ACETONITRILE 0 1481 5088 Scan 1962 (92.100 mtn) of ORTR:RCHER08R.0 28 _ 77 ~~ I ~ ~~ II~ ~~) II~I IIRf IIII 1 lg N58 BETR-I0N0L II 110$ !11 " l i N1118 PYRRZINE,tso-PROPENYL- 39 76 ~ / / II 119 k226 PRRR-CYMENE 1003 91 I` f100 50~ 119 50 0- i 1 ,.1i4 6 ~, a 0 50 100 150 200 ~ MacaiCharpa T: null. Z: Scan 196D (32.074 min) of GRAPHICSCO Y: TIC of DRTA:ACHEA08A.D [MS2] R: Set of 4 MS Scan 1962 (32.100 min) of DATA:ACHEA08A.D REGULAR-2 m/z abun d. m/z abund , m/z abund. m/ z abund, 28.15 42 55.15 4 8 92.15 29 111. 15 22 29.15 35 65.15 1 9 93.15 40 119. 15 92 32.15 22 67.15 2 2 94.15 23 120. 15 27 39.15 34 69.05 3 5 95.15 17 121. 15 42 41.25 1 00 77.15 3 7 105.15 71 123. 25 62 42.35 IS 79.15 3 3 106.15 18 133. 25 41 43.05 22 81.15 3 4 107.15 39 204. 25 15 53.05 29 91.15 4 8 109.25 23
Page 282: nbi31d00
LIBRARY SEARCH RESULTS Scan 2106 (33.941 min) of DATA:ACHEA08A.D REGULAR-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index it Quality 1: MENTHOL 0 132 8393 2: PHYTOL 0 55 7355 3: CYCLOHEXANE-1,2-DI0L,1,3,3-TRIMETHYL- 0 1629 7328 4: CAMPHOR-D 0 1547 7066 5: LINALOOL 0 1556 7032 6: LINOLEIC ACID, METHYL ESTER 0 1741 6898 7: IONONE,TETRAHYORO- 0 1503 6838 8: MARIOLIDE, DIHYDRO- 0 1745 6717 9: BICYCLO[440]DECANE,1559-ME-9-HO-10-OXO- 0 1747 6689 10: NEROLIDOL 0 1612 6622 Scan 2106 (33.941 ntn) of ORTR:RCHER06R.O 10 m.1~ ., 4 III~, ., i~R.. . 1iI'11.1. II9' 100 50 0 43 0122 MENTHOL ` 100 l5 ~ 1 4 11 95 129 1 13.1 43 k55 PHYTOL 95 ~1 ~i II 123 I /k1629 CYCLOHEXRNE-1.2-OIOL,1.3.3-TRIMETHYL- 00 ~, bo 43 I i5 .~'t 62 ~ 1 127 I I9'I i I I 42 60 60 100 120 Maes/Charge T: nu]]. Z: Scan 1962 (32.10D min) of GRRPHICSCO Y: TIC of DRTR:RCHER08R.D IMS2] X: Set of 4 MS Scan 2106 (33.941 min) of DATA:ACHEA08A.0 RE6ULAR-2 m/z abund. m/z abun d. m/z abund. m/ z abund. 28.15 11 55.15 67 77.05 4 96. 15 22 29.15 47 56.15 27 78.15 1 97. 15 5 31.15 11 57.15 42 79.15 7 99. 15 3 32.15 2 58.05 4 80.25 16 109. 15 11 39.15 42 59.05 2 81.15 83 110. 25 7 41.15 100 65.05 6 82.15 35 111. 25 2 42.25 20 67.15 48 83.15 12 112. 25 1 43.15 66 68.15 16 84.15 4 113. 15 1 44.15 11 69.15 37 85.15 8 123. 25 27 45.15 5 70.15 20 86.05 2 124. 25 3 50.15 1 71.05 99 91 _,09 2___ 138. 25 I 5_
Page 283: nbi31d00
LIBRARY SEARCH RESULTS Scan 5969 (83.199 min) of DATA:ACHEA07A.D LIGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: COTININE 0 12 9435 2: N-METHYL ANABASINE (SWW 20) 0 237 8792 3: PIPERIDINE,I-ETHYL- 0 1136 8358 4: 1,5-DIMETHYL-2-PYRROLIDINONE 0 40 8263 5: NORNICOTINE,N-ETHYL- (SL 39D) 0 878 7851 6: PYRROLIDIN-2-ONE,1,5-DIMETHYL- 0 1378 7682 7: PYRIDINE,3-(1-ET--2-PYRROLIDINYL)- 0 999 7501 8: PIPERIDINE,1-METHYL- I 1143 6926 9: PYRROLIDINE,N-ACETONYL- (SR199D) 0 832 6363 10: PIPERIDINE,2,3-DIMETHYL- I 1139 6382 Scan 5969 L69.199 m1n) of ORTR:RCHER07R.0 26 51 ,~ 119 147 176 96u~ i~ k1^c C07ININE 42 ~I 116 147 176 -r100 1ILL,/ I 5B ,~ T~ 0237 N-METHYL RNRBR9INE (SWW 20) a 42 70 / 119 r100 S 1 00 0 1 I. . i 9Bi 1 1 ~I 161136 PIPERIOINE.1^E7HYL- 100 E100 42 I 112 50 / 99 I / ~50 0 , i 1 , i ^^^I"',,, II a 0 20 40 60 60 100 1£0 140 160 _ MartiCharpe T: null. Z: Scan 5967 (83.173 min) of GRRPH]CSCU Y: T]C of DATR:ACHERD7R.D [MS2] X: Set of 4 MS Scan 5969 (83.199 min) of DATA:ACHEA07A.D LIGHTS-2 m/z abund. m/z abund. m/z abund. m/ z abund. 28.15 32 50.15 8 69.15 10 118. 15 16 32.05 6 51.15 19 70.15 7 119. 15 19 39.05 13 52.15 7 78.15 10 121. 15 9 41.15 17 55.15 6 79.15 8 147. 15 8 42.15 26 63.05 8 92.05 7 175. 25 11 43.15 6 65,05 8 98.15 100 176. 15 33 45.15 10 68.05 9 99.05 7
Page 284: nbi31d00
LIBRARY SEARCH RESULTS Scan 1960 (32.074 min) of DATA:ACHEAOSA.D REGULAR-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Index # Match Quality 1: BETA-IONOL 0 58 6562 2: BEN2ALDEHYDE,4-ISOPROPYL- 0 1408 5514 3: Kd 0 17 5387 4: PARA-CYMENE 0 226 5336 5: BENZONITRILE,4-HYDROXY- 0 1596 6268 6: PYRIDINE,2-METHYL-S-VINYL- 0 537 5218 7: SAFRANAL 0 1420 5208 8: Ka 0 14 5182 9: ACETOPHENONE, 4- METHYL- 0 1688 5112 10: PYRIDINE,S-METHYL-2-VINYL- (SBB 251D) 0 539 5006 Scan 1960 C32.074 m1n) cA DRTR:RCHER0BA.0 100 133 204 ~100 10 ~ 058 BETR-IkONOL 3 m8 u ~J ',1 53 11 1 ~'li 1! ~6 1 I ~ c A z5 c 014138 BENZRLOEHYOE,4- I50PR DPYL- 100 5 1 00 1 D Q /G 00 1 1~i 77 I~ ~ II k 11~5 , 17 Kd 139I L,~ 100 01 50 ~ 1 •'~~ 1I 1 •19 l8 ~ I 175 I 'y ~90 I ~k,5a F t r 40 60 60 100 120 140 160 160 200 Mass/Charye GRAPHICSCO (MS27 T: null. Z: Scan 1904 (31.360 min) of Y: T1C of DATA:ACHERD8A.D X: Set of 4 MS Scan 1960 (32.074 min) of DATA:ACHEA08A.D REGULAR-2 m/z abun d. m/ z abund. m/z abund. m/ z abund. 28.15 35 65. 15 25 94.1S 27 119. 15 100 29.25 45 67. 15 27 95.15 25 120. 25 31 32.15 19 69. 15 33 105.15 87 121. 15 53 39.15 43 77. 05 43 106.15 22 123. 25 58 41.15 93 79. 15 44 107.15 44 133. 25 45 43.05 22 81. 15 44 109.25 18 134. 15 21 53.05 31 91. 15 65 111.15 24 204. 25 22 55.15 52 93. 15 61 115.15 22
Page 285: nbi31d00
LIBRARY SEARCH RESULTS Scan 5972 (83.237 min) of DATA:ACHEA07A.D L.IGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: COTININE 0 12 9488 2: N-METHYL ANABASINE (SWW 2D) 0 237 8963 3: PIPERIDINE,I-ETHYL- 0 1136 8537 4: 1,5-DIMETHYL-2-PYRROLIDINONE 0 40 8447 5: NORNICOTINE,N-ETHYL- (SL 39D) 0 878 7943 6: PYRROLIDIN-2-ONE,1,5-DIMETHYL- 0 1378 7855 7: PYRIDINE,3-(I-ET-2-PYRROLIDINYL)- 0 999 7647 8: PIPERIDINE,1-METHYL- 1 1143 7099 9: PIPERIDINE,2,3-OIMETHYL- 1 1139 6543 10: 2-PIPERIDONE,6-METHYL- 0 787 6522 Bcan 5972 tB3.237 mtn) of ORTR:RCHER07R.D 100, 26 5 1 ~ .119 147 176 100 0 d ~ k12 COTININE 42 zI 11B 147 176 r'00 / lll.p0."'-` I 96 Ip237 N-METHYL RNR6RSINE (9WW 20) 42 ,~ 70 119 96 I I I. i ki136 PIPERIOINE,1-ETHYL- 100 / 1 100 42 g0I r------r1 9Br I i2 ~30 0 20 40 60 60 100 120 140 16 k0 _ Maic/CharBe T: null. Z: Scan 5969 (83.199 min) of GRAPHICSCD Y: TIC of DRTR:RCHERD7R.D [MS2] X: Set of 4 M5 Scan 5972 (83.237 min) of DATA:ACHEA07A.D L.IGHTS-2 m/z abund. m/z abund. ro/z abund, m/ z abund. 28.15 30 45.15 10 69.15 7 118. 15 12 31.15 8 50.15 9 70.15 10 119. 15 19 32.15 11 51.15 15 91.15 8 121. 15 9 39.15 12 52.05 9 98.15 100 147. 15 9 41.25 15 63.05 9 99.15 7 175. 15 10 42.15 28 65.15 8 117.15 6 176. 15 30 44.15 7 68.15 7
Page 286: nbi31d00
Data file: DATA:ACHEA08A.D File type: GC / MS DATA FILE Name Info: REGULAR-2 Misc Info: Dperator : JNS Date : 13 Aug 86 3:41 am Instrment: MS_5970 Inlet : GC Sequence index : Als bottle num : Replicate num • 1.IE7 TIC of ORTR!RCHER0BR.0 1.0E7 I 6. 0E6 a B . P1E 8 U C m a C 7. BEE E. BEE 5. 0E6 3 N n ¢ 4. BEB v m 3. 0E8 m m CW n Vt , m 4 E. BEE e m ~ to ~ N m 1.0E6 N h N ~ H 0 10 20 y0 46 S0 60 T1ma Cm1n.7 GRAPHICSCO [MS2] TIC of DATA:ACHEA08A.D REGULAR-2 7@ 90 90 106 T: Set of 4 MS Z: Scan 5999 (83.584 min) of Y: TIC of DRTR:RCHEAD7R.D X: TIC of DRTR:ACHEADBA.D ro PeakR Ret Time Type Width Area Start Time End Time 1 22 .349 BV 0.115 15192893 22.200 22.540 2 29 .679 BV 0.121 14866144 29.524 29.932 3 31 .324 PU 0.063 2199943 31.207 31.348 4 31 .358 VU 0.029 747576 31.348 31.400 5 32 .073 BV 0.078 9683572 31.908 32.089 6 32 .096 UV 0.056 6330623 32.089 32.290 7 33 .942 VV 0.106 196719154 33.694 34.118 8 43 .049 VV 0.107 3600999 42.903 43.177 9 43 .766 UV 0.208 1248921722 43.177 43.774 10 44 .264 VU 0.311 2955230881 43.774 44.853 11 52 .657 BB 0.152 45509439 52.464 52.999 12 57 .246 BB 0.170 35369264 57.098 57.646 13 82 .908 8B 0.282 100027907 82.549 83.486
Page 287: nbi31d00
LIBRARY SEARCH RESULTS Scan 3571 (52.653 min) of DATA:ACHER0BR.0 REGULAR-2 Library file: DRTA:TOBRCCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: TRIACETIN 0 235 9980 2: ACETIC ACID,2-OXOPROPYL ESTER 0 727 9865 3: 2(3H)-FURANONE,2-ACETOXY-4,5-DIHYDRO- 0 674 9862 4: ACETOL 0 192 9854 5: GLYCERIN,mono-acetete 0 728 9849 6: ACETIC ACID,2-FORMYLOXY-3-HOPROP ESTER 0 717 9846 7: MII-Vc 0 43 9841 8: PYRUVRLOEHYDE 0 799 9807 9: ACETIC ANHYDRIDE 0 1386 9795 10: ACETIC ANHYDRIDE 0 1731 9794 Bcar. 3571 (52.653 m1n) af DRTR:RCHER06R.0 26 73 103 Its 145 ~100 *235 TRIACETIN \ N 43 74 10~9~ k727 RCE7IC RCID,2-OXOPROPYL 73 I 43 .f 145 r'00 1,1 6 Iljrnaa_ i ESTER 1/1 6 8674 2C3H)-FLIRRNONE.2-RCETQXY-4.5-DIHYORO- 100 ` f10 S0~ I 49 72 0 / 0 20 40 60 B0 100 120 140 Nass/Charma ~ T: null. Z: Scan 2914 (44.269 ein) of GRRPHICSCO Y: TIC of DATA:ACHERDBA.D [M527 X: Set of 4 MS Scan 3571 (52.653 min) of DATA:ACHEA08A.D REGULAR-2 m/z abund. m/z abund. m/z abund. m/z abund. 28.15 3 43.15 100 70.15 1 103.15 11 29.15 2 44.15 3 73.05 2 115.25 3 31.05 I 45.15 1 74.06 I 116.15 4 32.05 1 57.15 1 86.05 2 145.15 8 41.25 1 61.05 1
Page 288: nbi31d00
LIBRARY SEARCH RESULTS Scan 5967 (83.173 min) of DATA:ACHEA07A.0 LIGHTS-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: COTININE 0 12 9752 2: N•-METHYL ANABASINE (SWW 2D) 0 237 9022 3: PIPERIOINE,1-ETHYL- 0 1136 8591 4: 1,5-DIMETHYL-2-PYRROLIOINONE 0 40 8529 5: NORNICOTINE,N-ETHYL- (SL 390) 0 878 8116 6: PYRROLIDIN-2-ONE,1,5-DIMETHYL- 0 1378 7938 7: PYRIDINE,3-(1-ET-2-PYRROLIDINYL)- 0 999 7746 8: PIPERIDINE,1-METHYL- 1 1143 7234 9: PIPERIDINE,2,3-OIMETHYL- 1 1139 6741 10: 2-PIPERIDONE,6-METHYL- 0 787 6720 Scan 5967 (83.173 mtn) of ORTReRCHER07R.0 42 51 ~ 119 147 176 10~ ~ ~I~~~ ~~.~..~ i~~ 42 / 012 COTININE I 116 9 6 .Ii i 147 176 ~ k'c37 N-METHYL RNRBRSINE (SWW 20) 42 713 / / 119 11 1 i g8, I. 1 I 0113E PIPERIOINE.1-ETHYL- 160 100 50 4% 96 112 ~Sm 0 i i'1 i i i 11 r i ---~ `0 0 20 40 60 80 100 12F1 140 160 MassiCharBe - _ T: null. Z: Scan 5961 (B3.095 min) of GRRPHICSCO Y: TIC of DRTR:RCHERD7R.D [MS27 X: Set of 4 MS Scan 5967 LIGHTS-2 (83.173 min) of DATA:ACHEA07A .D m/z abund. m/z abund. m/z ebund. m/ z abund. 28.15 29 50.15 8 69.15 8 117. 15 8 39.15 11 51.15 20 70.05 8 118. 15 15 41.25 20 52.05 8 77.15 8 119. 15 15 42.15 35 63.05 10 78.15 11 121. 15 8 43.25 7 64.95 6 91.05 7 147. 15 9 44.15 8 66.06 7 98.05 100 175, 15 11 45.25 7 68.05 9 99.15 9 176. 15 38
Page 289: nbi31d00
LIBRARY SEARCH RESULTS Scan 2876 (43.765 min) of DATA:ACHEA08A.D REGULAR-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Index # Metch Quality 1: NICOTINE 0 7 9830 2: NICOTINE 0 238 9830 3: NICOTINE,ISOMER (SL 190) 0 874 9049 4: PYRROLIDINE,2-ETHYL-1-METHYL- 1 1156 8755 5: PYRROLIDINE,1-PROPYL- 1 1155 8691 G: PYRROLIDINE,1-ETHYL- 1 1150 8278 7: ANABASINE 0 498 8248 8: PIPERIDINE,2-ETHYL- 0 1137 8164 9: PYRROLIDINE,2,5-DIMETHYL- 1 1151 8150 10: GLUTARIMIDE,3-METHOXY- 0 767 8117 Scan 2876 (43.765 mtn) Df DRTR:RCHER0BR.0 100 42 161 I ~100 ., .. ..~e~.~ .e.~ / ,64 ... ..~a._ . ...,. ,~ ..I. .. .i 07 NICOTINE 100 1 \ ('100 42 133 161 11 9 a u I , 64 ~ ~ n C p ~ N^c36 NICOTINE [ 3 1O0 1 3 \ -100 a / 161 1~ 9 3 ¢ J I i M674 NICOTINE.ISOMER (SL 191)7 1007 100 42 55 175 204 50~ ; 84 50 40 60 B0 100 120 140 Macs/Charga 160 1B0 200 T: null. Z: Scan 2821 (43.048 min) of CRAPHICSCO Y: TIC of DATA:ACHEAO8A.D [MS2) X; Set of 4 MS Scan 2876 REGU AR-2 (43.765 min) of DATA:ACHEA08 A.D L m/z abund. m/z abund. m/z abund. m/ z abund. 28.15 10 55.15 6 77.15 4 106. 15 2 29.15 2 56.15 2 78.05 6 107. 15 1 30.15 2 57.15 1 79.15 2 117. 15 4 37.15 I 58.25 1 80.15 2 118. 15 5 38.25 3 61.15 1 81.15 2 119. 15 9 39.15 13 62.05 2 82.15 7 120. 15 2 40.25 3 63.05 5 84.15 100 130. 15 4 41.25 10 64.15 3 85.15 6 131. 15 1 42.15 38 65.05 8 89.05 1 133. 15 29 43.15 3 66.05 2 90.15 1 134. 15 3 44.15 3 67.05 2 91.15 4 145. 15 1
Page 290: nbi31d00
LIBRARY SEARCH RESULTS Scan 828 (17.660 min) of DATA:ACHEA09A.D MENTHOL-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Index # 1: 2: 3: 4: 5: 6: 7: 8: 9: 10: DECANAL OCTANE-2,3-DIONE HEXANOIC ACID,4-METHYL-S-OXO- ALETIDINE UNDECANAL PYRIDINE,2-METHYL-S-ISOPROPANOL- PENTADECANAL F'URAN-2-ONE-(3H),4,5-DIHYDRO-3-HYDROXY- BUTYRALDEHYDE PROPANEDIOL-1,3 1561 1558 1529 1128 1764 1587 1454 1525 1412 1627 5can 826 (17.BE0 m1n) of l7RTR:RCHER09A.D 100 r100 I 4 3 I 57 I"`0007 0 815E1 OECRNRL 100 ~r~ 43 57 82 r100 0 I 28 ~ ~ ~I I I iu ~ ~~ III".999~ C m a IF1558 OCTRNE-2,3-0IQNE 10 71 9 9 1' 100 J 0~1i 128 43 I \ 2E L- GRRPH)CSCD CMS23 Ik1529 HEY,RNOIC RCI0.4-METHYL-5-OXO- -1r 4e .i 56 gB 100 4 3 74 12`6 ~ tl ~ , E0 E0 100 120 MasciCharae. T: null. Z: Scan 518 (13.715 min) of D V: TIC of DATR:ACHERD4A,D X: Set of 4 MS Match Quality 8612 8166 7352 7289 6946 6909 6543 6809 6389 6308 Scan 828 (17.660 min) of DATA:ACHEA09A,D MENTHOL-2 m/z abund. ra/z abund. m/z abund. m/z abund. 27.45 39 29.15 38 41.25 56 57,15 60 28.15 100 32.15 42 43.25 66
Page 291: nbi31d00
LIBRARY SEARCH RESULTS Scan 1772 (29.677 min) of DATA:ACHEAOBA.D REGULAR-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: PARA-CYMENE 0 226 7694 2: BEN20NITRILE,4-HYDROXY- 0 1596 7677 3: PYRAZINE,iso-PROPENYL- 0 1118 7507 4: PYRIDINE,2-METHYL-S-VINYL- 0 537 7362 5: PYRIDINE,S-METHYL-2-VINYL- (SBB 251D) 0 539 6975 6: BENZOXAZOLE 0 92 6493 7: PYRIDINE,3-ISOPROPENYL- 0 527 6485 8: ACETOPHENONE, 4- METHYL- 0 1688 6482 9: CYCLOPENTAPYRIZINE-SH,6,7-DIHYDRO- 0 1105 6473 10: 5H-CYCLOPENTAPYRAZINE,6,7-DIHYORO-5-Me- 0 589 6377 Scan 1772 C29.677 mtnl of ORTR:RCHER08R.Q 28 77 93 161 8226 PRRR-CYMENE 100 91 ~ r100 0 I m ii ttl9 II"`000~ M1596 BEN20NITRILE.4-HYOROXY- 27 yy 64 91 ~ / ~i iL 119 k1118 PYRRZINE.tso-PROPENYL- GG 70 100 G m 50 laa lsa 200 MesT/CharBB T: null. Z: Scan 1197 (22.354 mio) of GRRPHICSCD Y: TIC of DRTR:RCHEROBR.D [MS2) X: Set of 4 MS Scan 1772 (29.677 min) of DATA:ACHEA08A.D REGULAR-2 m/z abund. m/z abund. m/z abund. m/ z abund. 28.15 21 53.05 15 79.15 16 119. 15 100 29.25 15 55.15 17 81.15 10 120. 25 19 32.25 14 66.15 11 91.15 30 121. 25 15 39.15 19 65.05 12 92.15 14 133. 25 11 40,25 9 67.15 14 93.15 38 161. 15 22 41.15 52 69.15 22 105.15 32 204. 25 19 43.15 16 77.15 22
Page 292: nbi31d00
LIBRARY SEARCH RESULTS Scan 2914 (44.269 min) of DATA:ACHEA08A.D REGULAR-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: NICOTINE 0 7 9711 2: NICOTINE 0 236 9711 3: NICOTINE,ISOMER (SL 19D) 0 874 9101 4: PYRROLIOINE,I-PROPYL- 1 1155 8825 5: PYRRDLIDINE,2-ETHYL-I-METHYL- 1 1156 8609 6: PYRROLIDINE,1-ETHYL- 1 1150 8416 7: PYRROLIOINE,2,5-DIMETHYL- I 1151 8309 8: ANABASINE 0 498 8093 9: PIPERIDINE,2-ETHYL- 0 1137 8084 10: GLUTARIMIDE,3-METHOXY- 0 767 8038 Scan 2914 (44.269 min) of ORTR:RCHER0BR.0 100 4 ?~„ 100 ? 65 B 4 1/1 83 161 , ., ~ . 1. ~ 4 / i 4 / 2 \67 NICOTINE 116 139 161 (100 64 ~ ,i, ~~pfl~ \ 236 NICOTINE I 1~ g 64 - 3 0874 NICOTINE.ISOHER ey 513 \ /~ 164 40 GRRPHICSCD / 60 60 100 120 140 Mass/Charge 161 I ISO 160 r100 200 T: null. Z: Scan 2876 (43.765 min) of Y: TIC of DATR:RCHEA08R.D [MS2I X: Set of 4 MS Scan 2914 (44.289 min) of DATA:ACHEA08A.D REGULAR-2 m/z abund. m/z abund. m/z abund. m/z abund. 28.15 12 55.15 6 77.15 5 105.15 2 29.15 2 56.05 1 78.05 7 106.15 1 30.15 2 57.05 1 79.15 3 107.15 1 37.15 1 58.15 1 80.15 2 117.15 4 U' 38.25 4 62.15 2 81.15 2 118.15 6 w 9 39.15 15 63.05 7 82.15 6 . 119.15 8 tp ~ 40.15 3 64.15 3 84.15 100 120.15 2 r 41.25 10 65.05 8 85.15 5 130.15 4 kD 42.15 41 66.15 2 89.15 1 131.15 I 43.25 3 67.15 2 90.15 1 133.15 27 68.15 ______ 1 91.15 4 134.15 3
Page 293: nbi31d00
LIBRARY SEARCH RESULTS Scan 513 (13.651 min) of DATA:ACHEA09A.D MENTHOL-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS [k Library Match Index # Quality 1: DECANAL 0 1581 8518 2: OCTANE-2,3-DIONE 0 1558 8047 3: HEXANOIC ACID,4-METHYL-5-OXO- 0 1529 7105 4: AZETIDINE 0 1128 7046 5: PYRIDINE,2-METHYL-5-ISOPROPANOL- 0 1587 6921 6: UNDECANAL 0 1764 6875 7: FURAN-2-ONE-(3H),4,5-DIHYDRO-3-HYDROXY- 0 1525 6673 8: PROPANEDIOL-1,3 0 1627 6383 9: PYRROLE-2-CARBOXAMIDE 0 1567 6247 10: BUTYRAMIDE,2-METHYL- 0 1565 6042 5can 513 (13.E51 m1n) ef ORTRfRCHER09R.I) 100 ~/~ ,I I2B 0 100,`~` 0 Jl EB u c N ,- ~ I I 43 I 57 #1581 DECRNRL 43 57 B2 a #1558 OCTRNE-E,3-DIONE ~ 1 0 0 \`. ~. 7 1 9 9 ~' 1 0 0 IL~~ ¢ a ~ 128 43 0 #15'cB HEXRNOIC RCI0.4-METHYL-5-oX0- 100 `--- 50 EE 43 0 40 GRAPHICSCO [MS27 T: null. Z: Scan 5 (7.185 min) of DATA Y: TIC of DATR:ACHER09A.D X: Set of 4 MS Scan 513 (13.651 min) of DATA:ACHEA09A.D MENTHDL-2 m/z abund. m/z abund. 28.15 100 32.15 64 29.15 46 41.15 55 SB 74 BE s 1 00 1 FS0 ~ . 13 E0 E0 100 1 2 0 Masc/CharBQ m/z abund. m/z abund. Ln ~ 43.15 56 57,05 61 m 00 J Y 01 ch
Page 294: nbi31d00
LIBRARY SEARCH RESULTS Scan 3930 (57.244 min) of DATA:ACHEAOBA.D REGULAR-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: MYOSMINE 0 10 9587 2: BENZONITRILE,2-AMIND- 0 1488 7290 3: PYRROLE[1,2a]PYRAZINE,3,6-DIMETHYL- 0 1371 7158 4: PYRIDINE,2-(1-PROPENYL)- (SBB 2360) 0 643 7063 5: BENZIMIDAZOLE 0 95 6982 6: TETRALONE-1 0 834 6915 7: BENZIMIDAZOLE 0 614 6903 B: IMIDAZO[1,2a]PYRIDINE 0 968 6829 9: PYRIDINE,3-CYANO-4-METHYL- (SWW 100D) 0 275 6759 10: BENZOFURAN 0 628 6634 5can 3930 S57.Z44 39 51 mtn9 of ORTReRCHER08R.0 76 105 100 / i6 1a ~~ J ~I 0113 MY09MINE 51 78 10 y.... I I 1 11 1 1 B 1 4 6 ~I k14BB BENZONITRILE,2-RMINO- 63 64 91 ~~~ ~ 116 /k1371 39 ~ 51 PYRROLEC1.2a]PYRRZINE,3.6-CIIMETHYL- 0 I 1 0 20 40 60 60 MassiCharp® GRAPHICSCD [MS2] 104 11B ,.~ 100 1 4 B 50 106 120 140 T: nu] l. Z: Scan 3571 (52.653 min) of Y: TIC of DRTR:RCHEROBR.D X: Set of 4 MS Scan 3930 (57.244 min) of DATA:ACHEA0BA.0 REGULAR-2 m/z abund. m/z abund. m/z abund, m/ z abund. 28.15 18 42.15 16 65.05 11 105. 15 18 32.15 6 50.15 13 76.05 8 118. 15 100 37.15 6 51.15 20 77.15 11 119. 15 9 38.15 10 52.05 9 78.05 26 145. 25 50 39.15 25 62.05 7 91.05 11 146. 15 58 40.15 8 63.05 15 104.15 8 147. 25 6 41.15 24 64.05 12
Page 295: nbi31d00
LIBRARY SEARCH RESULTS Scan 518 (13.715 min) of DATA:ACHEA09A.D MENTHOL-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS tt Library Match Index it Quality 1: PENTADECANAL 0 1454 8557 2: TRIDECANAL 0 1478 8210 3: 3-HEXANONE 0 469 8151 4: HEPTANE-2,5-DIONE 0 1530 7757 5: FURANONE-2(3H), 4,5-HYDRO-3-HYDROXY-3-ME 0 1646 7709 6: UNDECANAL 0 1764 7618 7: PENTANEDIONE-2,3 0 1350 7594 8: HEPTAN-2,5-DIONE 0 1506 7513 9: PYRAN-2-ONE,3,4,5,6-TETRAHYDRO-4-OH- 0 709 7488 10: FURANONE-2(3H), 4,5-HYDRO-3,3-DIME-4-HO- 0 1647 7483 Scan 516 (13.715 mtn) of DRTA:RCHERB9R.0 100l 4 '.' rlpp 0J II 6~ I 3 37 10~ ` 0~ IP9 ifa0, P9 JI 14 100 ~ 5 0, qllllh~3 0 20 40 GRAPHICSCD [MS2] k1454 PENTROECRNRL f 67 71 B^s S7III ~I I ~ 01478 TRIDECANRL // 66 6s 57~I ~IIi~ 16469 3-HEXRNONE r..- 71 10,,0~ [E1B0 57 l f" " '` B3 ~~'3® ima 50 60 70 60 90 100 MassiChar~e ___ T: null. Z: Scan 513 (13.651 min) of D Y: TIC of DATA:ACHEA09A.D X: Set of 4 MS Scan 518 (13.715 min) of DATA:ACHEA09A.D MENTHOL-2 m/z abund. m/z abund. m/z abund. m/z abund. 28.15 59 32.15 36 43.15 100 57.15 93 29.15 65 41.15 67 55.25 31 71.15 46
Page 296: nbi31d00
LIBRARY SEARCH RESULTS Scan 1332 (24.077 min) of DATA:ACHEA09A.D MENTHOL-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Index # 1: DECANAL 2: OCTANE-2,3-DIONE 3: UNDECANAL 4: HEX-3-EN-2-DNE,5-METHYL- 5: HEXANOIC ACID,4-METHYL-S-OXO- 6: PENTAOECANAL 7: TRIDECANAL 8: OCTADECANOL 9: NONANAL 10: TETRADECANAL 1561 1558 1764 1504 1529 1454 1478 1818 1434 1475 Scan 1332 (24.077 min) of DRTReRCHER09R.0 IO~J~ '1 I f1 1'l7 F9 ~'100 k1561 DECANAL 100 N 41 57 28 6E / ~ 0 ~ ~ Y ~1 I I i~i c 4 ~ 01558 OCTRNE-E.B-DIPNE 5 100 ~~ ~ 01 g 39 ~ 55 71 , ^c1 ~I3 01784 IJNOECRNRL 100 BS 100 50~ I g I ~ 0 I 30 40 50 60 70 60 90 Mass/Chsrge_ GRRPHICSCO [MS2] T: null. 2: Scan 1165 (21.951 min) of Y: T1C of DRTA:RCHEA09R.D X: Set of 4 MS Match Quality 8074 7598 7479 6890 6881 6812 6670 6572 6421 6326 Scan 1332 (24.077 min) of DATA:ACHEA09A.D MENTHOL-2 m/z abund. m/z abund. m/z abund. m/z abund. 28.15 100 32.15 76 43.15 75 57.15 51 29.15 46 41.15 94 55.15 48 69.05 40
Page 297: nbi31d00
LIBRARY SEARCH RESULTS Scan 5944 (82.910 min) of DATA:ACHEAOBA.D REGULAR-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: COTININE 0 12 9651 2: N--METHYL ANABASINE (SWW 2D) 0 237 9085 3: PIPERIDINE,1-ETHYL- 0 1136 8610 4: 1,S-DIMETHYL-2-PYRROLIDINONE 0 40 8659 S: NORNICOTINE,N-ETHYL- (SL 39D) 0 878 80B9 6: PYRROLIOIN-2-ONE,1,5-DIMETHYL- 0 1378 7969 7: PYRIDINE,3-(1-ET-2-PYRRQLIDINYL)- 0 999 77S1 8: PIPERIDINE,1-METHYL- 1 1143 7287 9: PIPERIOINE,2,3-DIMETHYL- 1 1139 6821 10: 2-PIPERIODNE,6-METHYL- 0 787 6800 Bcan 5944 (B2.910 m1n) of DRTR:RCHERBBR.II 42 51 119 147 176 ~100 1. LIL~ .ubi.a. 913 d n. AI ` y /44 012 CDTININE 42 ~ 118 147 176 r'Wla / ILp~- I 9B ill~ I~ GAAPH)CSC6 [MS2) k297 N-METHYL RNRBR9INE (SWW 2D) 42 70 / / 119 1. . l 96i I I /1113fi PIPERIqINE.1-ETHYL- 42 9B 11 I 112 r1 lL, _, 26 40 60 BB 162 120 l40 160 Matl,iCharpe T: null. Z: Scan 3930 (57.244 min) of Y: TIC of DATA:ACHEA08A.D X: Set of 4 MS Scan 5944 (82.910 min) of DATA:ACHEA08A.D REGULAR- m/z 2 abund. m/z abund. m/z abund. m/ z abund. 28.1 5 19 50.25 7 69.15 10 104. 15 .3 29.1 5 5 51.15 18 70.05 6 105. 15 3 30.1 5 4 52.15 B 76.05 4 106. 15 4 32.2 5 2 54.15 3 77.15 4 117. 15 7 38.2 5 S 55.05 6 78.05 11 118. 15 1? 39.1 5 13 56.05 3 79.15 6 119. 15 1 40.2 5 3 62.15 3 80.05 6 120. 15 41.1 5 14 63.05 9 90.25 3 121. 15 7 42.1 5 38 64.15 5 91.05 9 147. 15 9 43.1 5 5 65.05 10 92.05 6 175. 15 11 va.m s 3 66.05 3 98.05 100 176. 15 37
Page 298: nbi31d00
LIBRARY SEARCH RESULTS Scan 1165 (21.951 min) of DATA:ACHEA09A.D MENTHOL-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: 3-HEXANONE 0 469 8968 2: TRIDECANAL 0 1478 8816 3: PENTADECANAL 0 1454 8811 4: HYDROCARBON 0 32 8417 5: NONANAL 0 1434 8076 6: PYRAN-2-ONE,3,4,5,6-TETRAHYDRO-4-OH- 0 709 8066 7: PYRROLIOIN-2-CARBOXALDEHYDE 0 1474 8020 8: FURANONE-2(3H), 4,5-HYDRO-3,3-0IME-4-H0- 0 1647 8019 9: 1,3-DIOXOLAN-2-ONE,4-METHYL- 0 730 7959 10: FURAN-2-ONE(3H),4,5-DIHYDRO-3,4,4-METHYL 0 1659 7934 Scar~ 1165 (21_951 min) of DRTR:RCHER09R.0 lI E9 ' ~ 85 iG0 10 0 OJI~ i li3 57III ~fll1 I ~8 I 43 0469 3-HEXRNONE 71 57 i, 1. 0147B TRI0ECRNRL 6B ..69 57II) II I 1 z 16_B j 100 `B 01454 PENTROECRNRL ~'IBB iR0 ,,,,'6 7 7 1 B E ~ 50~ ~ E9 3 57111 ~ ~ 7 ~50 2 1 I I I I " T^^-^I~YJ 30 40 5m 60 70 60 90 !p0 _ MassiCharpo T: null. Z: Scan 828 (17.660 min) of D GRRPHICSCO Y: TIC of DRTR:flCHEAD9A.D [MS21 X: Set of 4 MS Scan 1165 (21.951 mi.n) of DATA:ACHEA09A.D MENTHOL-2 m/z abund. m/z abund. m/z abund. m/z abund. 28.15 20 42.25 19 56.15 20 70.15 13 29.15 39 43.25 100 57.15 87 71.15 51 39.15 13 55.15 25 69.15 12 85.15 34 41.15 63
Page 299: nbi31d00
LIBRARY SEARCH RESULTS Scan 1410 (25.070 min) of OATA:ACHEA09A.D MENTHOL-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # 1: CYCLOHEXANONE, 2-ISOPRDPYL-5-METHYL- 0 2: CYCLOTENE 0 3: 2-(5H)-FURANONE,2,4-DIMETHYL- (SNN 880) 0 4: OCTADECANOL 0 5: OCTEN-6-AL,3,7-DIMETHYL- 0 6: UNDECANOL 0 7: CYCLOHEXANONE,2,3-EPOXY-3,5,5-TRIMETHYL- 0 8: NONA-2,4-DIENAL 0 9: NONYL ALCOHOL 0 10: OLEIC ACID, METHYL ESTER 0 Scan 1410 (25.070 m1n) af ORTReRCHER09R.C1 100 ,'~ ~` ~ B3 ~~ 139 0J, k176 9 CYCLOHEXRNONE, E-ISOPROPYL-5-METHYL- ~ ,}},,10~~ 11 ~I ~1 100 50 0 Library Match Index # Quality 1769 9078 1625 8757 365 8101 1818 8055 1453 8014 1765 7937 1526 7729 1447 7683 1771 7683 1736 7633 Z: Scan 1332 (24.077 min) of ~ I ~ II 69 1~1c' iF365 E-(SH)-PLJRRNONE,E.4-OINETHYL- (SNN B60) 67 11E 53 9 ~.,. / 40 60 B0 100 120 140 MasciCharge T: null. ^ GRAPHICSCO Y: TIC of OATA:ACHEA09A.D [MS2] X: Set of 4 MS Scan 1410 (25.070 min) of DATA:ACHEA09A.D MENTHOL-2 m/z abund. m/z abund. 28.15 54 29.15 36 32.15 31 39.15 42 40.25 23 W16E5 CYCLOTENE 41.15 100 42.15 25 43.25 50 55.15 60 m/z abund, m/z abund. 56.15 37 97.15 21 69.05 68 111.25 24 70.05 28 112.15 67 83.15 24 139.25 24
Page 300: nbi31d00
LIBRARY SEARCH RESULTS Scan 1935 (31.754 Min) of DATA:ACHEA09A.D MENTHOL-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Index # 1: DECANAL 2: OCTANE-2,3-DIONE 3: 3-HEXANONE 4: HEPTANE-2,5-DIONE 5: HEXANOIC ACI0,4-METHYL-S-OXO- 6: FURAN-2-ONE-(3H),4,5-DIHYDRO-3-HYDROXY- 7: HEPTAN-2,5-DIONE 8: PENTADECANAL 9: FURANONE-2(3H), 4,5-HYDRO-3,3-DIME-4-HD- 10: UNDECANAL 1561 1558 459 1530 1529 1525 1506 1454 1647 1764 Scan 1935 (31.754 m1n) of ORTR!RCHER99R.0 100 II ~ ~'13 5 I 71 /'160 k1561 DECRNRL 1©0 `~ 41 57 62 t m ~ k155B OCTRNE-2.9-OIONE ~ 1©0--II ~ 71 3 ~p 55 ¢ 0~i IB i13 l I 160 50 ~ B ~-^.-^-.-~+r+ 30 40 6RRPH]CSCD [M52] t B`, r'00 /111,,,,,, k469 3-HEXANONE 71 Ft100 3 I i 69 ~50 513 6m 70 80 9m 10€0 MassiChargc T: null. Z: Scen 1932 (31.715 min) of Y: TIC of DRTA:RCHERD9R.D X: Set of 4 MS Match Quality 8184 B055 7296 7296 7189 7078 7036 6897 6852 6816 Scan 1935 (31,754 min) of DATA:ACHEA09A.D MENTHOL-2 m/z abund. m/z abund. m/z abund. m/z abund. 28.15 100 32.05 41 43.15 85 71.15 50 29.15 48 41.15 50 57.15 83
Page 301: nbi31d00
LIBRARY SEARCH RESULTS Scan 5(7.185 min) of DATA:ACHEA09A.D MENTHOL-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index II Quality I: 1,4-PYRAN,2,3-OIHYDRO-2-FORMYL- 0 380 7120 2: SR 79C 0 73 6722 3: URACIL,5,6-DIHYDRO-3-ETHYL-S-METHYL- W22 0 944 6284 4: DIHYDR080VOLIDE (SR 57C) 0 66 5930 5: 3-HEXEN-2-ONE 0 464 5610 6: ACETONITRILE,2-(N,N-DIMETHYLAMINO)- 0 1482 5511 7: 2-(3H)-FURANONE,4,5-DIHYORO-5-HYDROXYMe- 0 708 4721 8: GAMMA-NONALACTONE 0 20 4644 9: GAMMA-DECALACTONE 0 96 4622 10: 2(3H)-FURANONE,S-CARBOXYLATE-4,5-HYDRO- 0 675 4597 Bcan 5 (7.165 m1n) nf ORTR:RCHER09R.D 32 47 67 63 0380 1.4-PYRRN,E,3-OIHYORO-2-FQRMYL- 39 1^c_0 fi00 1/1 Y ~ 073 SR 79C ~ 100 51 ~ r1 00 ¢ ~ iI,55 83 11 / 11/ 03 0 6944 IJRRCIL,5,fi-t)IHYOR0-3-ETHYL-5-METHYL- W22 1003 42 55 / F100 83, 98 ~50 0 r- I I i 0 20 40 60 60 100 Mass/Charge T: null. Z: TIC of DATR:ACHEAU9R.D GRAPHICSCO Y: T1C of DRTR:ACHER09A.D [MS2I X: Set of 4 MS Scan 5 (7.185 min) of DATA:ACHEA09A.D MENTHOL-2 m/z abund. m/z abund. m/z abund. m/z abund. 28.15 2 32.15 2 35.05 27 36.15 4 37.05 10 41.15 1 51.15 41.65 1 69.95 47.15 42 72.05 48.15 18 82.95 49.15 24 84.05 4 85.95 5 2 87.05 10 1 118.05 2 100 118.95 1 15 119.95 2 38.15 1 50.15 7 84.95 64
Page 302: nbi31d00
LIBRARY SEARCH RESULTS Scan 1932 (31.715 min) of DATA:ACHEA09A,D MENTHOL-2 Library file: DATR:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: 3-HEXANONE 0 469 8070 2: DECANAL 0 1561 7736 3: FURANONE-2(3H), 4,5-HYDRO-3,3-DIME-4-HO- 0 1647 7669 4: PENTADECANAL 0 1454 7487 5: TRIDECANAL 0 1478 7400 6: HEPTANE-2,5-DIONE 0 1530 7395 7: PYRAN-2-ONE,3,4,5,6-TETRAHYDRO-4-OH- 0 709 7249 8: OCTANE-2,3-DIONE 0 1558 7193 9: HEPTAN-2,5-DIONE 0 1506 7154 10: UNDECANAL 0 1764 7082 Scan 1932 (31.715 min) of ORTR:RCHER09R.0 100 .~ / ,~ r100 ~I 26 I 3 57 1 I 71 1 0 #469 3-HEXRNONE I ~3 57 I ~ 3 IC~p Z 1 41 ¢ 0J1 2B I I~ 71 11 K1561 OECRNRL 57 B2 t I ~. 01647 FLIRRNGNE-2C3H7. 4.5-HYORQ-3.3-0IME-4-H0- 100 89 _ 66 N 100 ,~ 5D I' I I y3 57 ( ` If71 ~30 0 r i ll ^f~ ~- --i'0 30 40 50 60 70 60 90 100 _ Mass/Charya T: null. Z: Scan 1418 (25.070 min) of GRRPHICSCD Y: T1C of DRTR:RCHEA09A.D [MS2) X: Set of 4 MS Scan 1932 (31.715 min) of DATA:ACHEA09A.D MENTHOL-2 m/z abund. m/z abund. m/z abund, m/z abund. u 28.15 93 41.25 79 57.15 98 71.15 71 w 29.25 41 43.15 100 m tb -j N a+ N
Page 303: nbi31d00
53.05 18 71.15 91 93.15 3 139.25 1 54.25 9 72.15 4 95.15 54 LIBRARY SEARCH RESULTS Scan 2198 (35.129 min) of DATA:ACHEA09A.D MENTHOL-2 Library file: OATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: OCTANE-2,3-DIONE 0 1558 7232 2: DECANAL 0 1561 6956 3: FURFURYL ALCOHOL, TETRAHYDRO- 0 1687 6277 4: HEXANOIC ACID,4-METHYL-5-OXO- 0 1529 6175 5: HEPTANONE-4 0 1784 6042 6: MENTHOL 0 132 5966 7: UNDECANAL 0 1764 5880 8: PYRIDINE,2-METHYL-S-ISOPROPANOL- 0 1587 5720 9: CYCLOHEXANE-1,2-DIOL,1,3,3-TRIMETHYL- 0 1629 5633 10: FURANONE-2(3H), 4,5-HYDRO-3,3-DIME-4-HO- 0 1647 5553 Scan 219B (35.1f9 m1n) oA ORTR:RCHER09R.0 100JI '1 I'i3 I'll IB1 q5 r'00 N155B OCTRNE-2.3-GIONE 1GG \` , 55 71 o (']0 2 1 f ~ i'13 g 0 c m ~ 01561 OECRNRL r100 a 100 \.~ 41 57 B2 ¢ G l 26 1 11 I I / . i i II«<999 k1667 FURFURYL RLCOHOL. TETRRHYORD- 100'~ 31 E100 50~I 19~199 3 I 7 1 ~tl0 I 30 40 50 60 70 BB 90 Mass/Charge T: null. Z: Scan 2153 (34.553 nin) of GRAPHICSCO Y: TIC of DRTR:RCHER09R.D [MS2) X: Set of 4 MS Scan 2198 (35.129 min) of DATA:ACHEA09A.D MENTHOL-2 m/z abund. m/z abund. 28.15 100 41.15 69 29.15 59 43.15 74 32.15 51 m/z abund. m/z abund. 67.15 57 81.05 54 '^ ~ 71.05 77 95.15 50 w m OD V 1-~ O1
Page 304: nbi31d00
50.15 5 69.05 1 93.15 2 159.15 1 51.15 12 75.05 1 103.15 1 161.15 12 52.15 5 76.15 1 104.15 2 162.15 11 53.15 2 77.15 4 105.15 2 163.15 1 LIBRARY SEARCH RESULTS Scan 2928 (44.461 min) of DATA:ACHEA09A.D MENTHOL-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: NICOTINE 0 7 9906 2: NICOTINE 0 236 9906 3: NICOTINE,ISOMER (SL 19D) 0 874 9074 4: PYRROLIDINE,2-ETHYL-1-METHYL- 1 1156 8734 5: PYRROLIOINE,1-PROPYL- I 1155 8599 6: ANABASINE 0 498 8377 7: PIPERIDINE,2-ETHYL- 0 1137 8201 8: PYRROLIDINE,1-ETHYL- 1 1150 8190 9: GLUTARIMIDE,3-METHOXY- 0 767 8183 10: PYRROLIDINE,2,5-DIMETHYL- 1 1151 8059 Scan 2928 (44.481 mtn) af ORTR:RCHER09R.0 100 1 ~ 41 6 5 I 1 113 133 161 `IL"`.0000100 84 / / 0 .. a.~~.. .~.,,~.. ...~... ...,..~ . . ~ 100 501 4 / 2 1 i #E74 NICOTINE,ISOMER 42 55 N7 NICOTINE I~ 1 1 9 ,r.3 3 IB4 / ~ \ 236 NICOTINE 13 161 ~'00 64 1%9 3 i ~, 1 L01 N 1e1 u (9L 19Q] 175 224 / I 184 40 60 60 100 120 140 160 Mast/Charge T: null. 160 200 100 Z: Scan 2896 (44.041 min) of GRAPHICSCO Y: TIC of DRTR:ACHEA09A.D [MS21 X: Set of 4 MS Scan 2928 (44.461 min) of DATA:ACHEA09A.D MENTHOL- m/z 2 abund. m/z abund. m/z abund. m/ z abund. 28.1 5 12 52.05 5 69.15 2 104. 15 2 29.2 5 4 53.15 2 77.15 5 108. 15 2 32.2 5 3 54.15 3 78.05 6 117. 15 4 38.2 5 3 55.05 8 79.05 4 118. 15 6 39.1 5 14 56.15 2 81.15 3 119. 15 9 40.2 5 3 57.05 2 82.15 7 120. 15 3 41.1 5 10 62.15 2 84.15 100 130. 15 4 42.1 5 34 63.05 6 85.15 7 133. 15 32 43.1 5 5 64.05 4 89.25 2 134. 15 4 44.1 5 5 65.05 9 91.15 4 161. 15 15 50.1 5 6 67.05 3 92.05 7 162. 15 t~
Page 305: nbi31d00
LIBRARY SEARCH RESULTS Scan 2141 (34.397 min) of DATA:ACHEA09A.D MENTHOL-2 Library file: DATR:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CR9 II Library Match Index >k Quality 1: MENTHOL 0 132 8092 2: PHYTOL 0 55 7455 3: CYCLOHEXRNE-1,2-DIOL,1,3,3-TRIMETHYL- 0 1629 7136 4: NEOPHYTADIENE 0 1601 7116 5: LINALOOL 0 1556 6818 6: PENTADECANAL 0 1454 6766 7: TRIDECRNAL 0 1478 6717 8: LINOLEIC ACID, METHYL ESTER 0 1741 6713 9: CYCLOHEXANE-1,2-DIOL, 1-METHYL- 0 1716 6577 10: HEPTANONE-4 0 1784 6561 ~ Bcan 2141 (34.397 m/n) nf GRTR:RCHER09R.G 100 J 41 I 95 1E9 136 100 0132 MENTHOL u 100] 49 I l5 ~ 71{ ll1 I 5 12 136 r'00 ~ ~c m ° /`k55 PHYTOL = 1~°,I / ,{ I{ g 95 123 r1°° ¢ 0J 43 Ik1ti29 CYCLOHEXRNE-l.2-OIDL.1,3.3-TRIMETHYL- 50~+ ]JT-.^-.li/0 40 55 / ~ f 92 60 80 100 MassiCharg® GRRPHICSCO [HS2] 100 50 T: null. Z: Scnn 1935 (31.754 min) of Y: TIC of DRTR:RCHER09R.D X: Set of 4 MS Scan 2141 (34.397 min) of DATA:ACHEA09A.D MENTHOL-2 m/z abu nd. m/z abund . m/Z abund. m/ z abund. 28.25 12 54.25 1 0 72.15 S 95. 15 55 29.15 52 55.15 6 0 73.15 1 96. 15 19 30.25 2 56.15 2 5 77.05 4 97. 15 4 31.15 12 57.15 4 2 79.15 7 99. 15 2 39.15 42 58.05 3 80.25 13 109. 25 10 41.15 100 59.05 2 81.15 74 110. 25 6 42.25 18 63.05 1 82.15 31 111. 15 I 43.15 62 65.05 4 83.15 10 112. 25 1 44.15 11 67.15 4 1 84.15 3 113. 15 1 45.15 5 68.15 1 4 85.15 8 123. 25 23 r.n tr, I F9.1S A: 4 AF,.iF ii 174. 7.ri 7
Page 306: nbi31d00
LIBRARY SEARCH RESULTS Scan 2893 (44.002 min) of DATA:ACHEA09A.D MENTHOL-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # 1: NICOTINE 0 2: NICOTINE 0 3: NICOTINE,ISOMER (SL 19D) 0 4: PYRROLIDINE,2-ETHYL-1-METHYL- 1 5: PYRROLIDINE,1-PROPYL- 1 6: PYRROLIDINE,1-ETHYL- 1 7: ANABASINE 0 8: PIPERIDINE,2-ETHYL- 0 9: PYRROLIDINE,2,5-DIMETHYL- 1 10: GLUTARIMIDE,3-METHOXY- 0 /00 50 0 Scan 2893 (44.002 m1n) of ORTR:RCHER09R.D 2 4 2 6 5 \ ..... 1~1 B i. 3 162 I. ,,.... ..!_ .. ....... . ..... I. . .. 4 / 2 1 4 / 2 1 \ k7 NICOTINE 119 r 3 161 168 M246 NICOTINE 161 64 I 1. li Library Match Index # Quality 7 9835 236 9835 874 9126 1156 8787 1155 8750 1150 8334 498 8258 1137 8250 1151 8204 767 8203 100 16874 NICOTINE,ISOMER (SL 190) I I N 175 204 l00 55 `/ 84 40 80 B0 100 120 140 180 160 200 Masx/Chartae GRAPHICSCO IMS27 T: null. Z: Scan 2198 (35.129 min) of Y: TIC of DRTA:ACHERD9R.D X: Set of 4 MS Scan 2893 (44.002 min) of OATA:ACHEA09A.D MENTHOL-2 m/z abund. m/z abund. m/z abund. m/ z abund. 28.15 11 54.15 3 78.05 7 106. 15 1 29.15 2 55.05 5 79.05 2 107. 15 1 30.15 2 56.05 1 80.15 2 117. 15 4 37.15 1 57.15 1 81.15 2 118. 15 5 38.25 3 62.15 2 82.15 6 119. 15 8 39.15 13 63.05 6 84.15 100 120. 15 2 40.15 3 64.15 4 85.15 5 130. 15 4 41.25 10 65.05 8 89.05 1 131. 15 1 42.15 37 66.05 2 90.15 1 133. 15 27 43.15 2 67.05 2 91.15 4 134. 15 3 ad ts 3 68.15 1 92.05 7 145. 25 r 9 119
Page 307: nbi31d00
51,15 4 70.25 18 91.15 53.05 17 71.15 93 93.15 LIBRARY SEARCH RESULTS 2 4 138.25 139.25 12 2 Scan 2153 (34.553 min) of DATA:ACHEA09A.D MENTHOL-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS AS # ibrary Index # atch Quality 1: MENTHOL 0 132 8043 2: PHYTOL 0 55 7417 3: CYCLOHEXANE-1,2-DIOL,1,3,3-TRIMETHYL- 0 1629 7163 4: NEOPHYTADIENE 0 1601 7103 5: LINALOOL 0 1556 6870 6: PENTADECANAL 0 1454 6759 7: TRIDECANAL 0 1478 6693 8: LINOLEIC ACID, METHYL ESTER 0 1741 6686 9: HEPTANONE-4 0 1784 6609 10: CYCLOHEXANE-1,2-DIOL, 1-METHYL- 0 1716 6603 Bcar, 2153 (34.553 mtn) of DATRfRCHER09R.0 100 ~ 4 123 13B 100 4 I ~ J i 0 k1 32 MENTHOL 1001 ` r100 ( 12 3 136 a , 0 4 3 I '15 g ~ ~ ~I c m ~ 055 PHYTOL c 3 100, 5 123 ~'100 n Q J0 4 3 9~~ Ii I 1k1629 CYCLOHE7iRNE-1. 2-DIOL.1.3, 3-TRIME THY L- 100 / I ~ 5 82 111 12~ 100 50L 0 48 II 1 1 ..1J'I-- 50 40 60 B0 100 Mass/Char6e _ GRRPHICSCD [M521 120 140 T: nul). Z: Scan 2141 (34.397 mio) of Y: TIC of DATR:RCHERD9R.D X: Set of 4 MS Scan 2153 (34.553 min) of DATA:ACHEA09A,0 MENTHOL-2 m/z abund. m/z abund. m/z abund. m/ z abund. 28.25 11 55.1 5 58 73.15 1 96. 15 18 29.15 53 56.1 5 23 77.05 4 97. 15 3 31.15 12 57.1 5 39 79.15 7 99. 15 3 39.15 42 58.0 5 4 80.15 13 109. 25 9 41.15 100 59.0 5 2 81.15 71 110. 25 5 42.25 17 63,0 5 1 82.15 29 111. 25 1 43.15 61 65.0 5 4 83.15 10 112. 25 1 44.15 10 67.1 5 39 84.15 3 113. 25 1 45.15 5 68.1 5 13 85.15 7 123. 25 23 50.15 1 69.1 5 32 86.15 2 124. 15 2 ti:_iS 4 70.2 5 18 91.05 2 138. 25 11
Page 308: nbi31d00
Data file: DATA<ACHEA0IA.D File type: GC / MS DATA FILE Naine Info: LIGHTS EXTRACT Misc Info: Operator : JNS Date : 12 Aug 86 2:23 pm Instrnent: M5 5970 Inlet : .riC Sequence indett . AIs bottle nun • Replicate nuro r I 5. OE7 fIL oY I 6. DE7 ~ ~ OES~ fi. uE5 ~ ~. EDE7 la I3 4. 0E5 n ¢ 3. DE5 2. 0E5 1.6E5 LfHIH:MCHlHNIH.U ED ?0 CftAPH]CSCD T: T]C of DATR:ACHEflD1A.D Z: TIC of DATR:ACHEADIA.D Y: TIC of DATAtACHEADiA.D [MS2] X: TIC of DATR:RCHEADIR.D TIC of DATA:,;CHEA0IA.D L:CurS EXTOA~T Pcak4 P,at Tiroe Typc Width Arca Start Ti-a End Time 1 31.787 VV 0.107 4503549 31.676 31.915 2 31.936 VV 0.041 401455 31.915 32.001 3 42.642 VV 0.154 8262395 42.498 42.856 4 43.220 PV 0.141 82494955 43.013 43.382 5 43.439 VV 0.074 13531811 43.382 43.460 6 43.476 UU 0.110 27125180 43.460 43.711 7 44.043 J'J 0.:57 124189540 43.785 44.112 8 44.120 VV 0.246 131111989 44.112 44.475 9 40.483 Vl! 0.049 11444960 44.475 44.527 ?0 44.538 V'.' 0.069 14171957 44.527 44.602 !? 44.808 U6' 0.!03 15877144 44.787 44.961 ?2 44.978 i'J 0.046 3945678 44.951 45.003 ?3 45.746 V'J 0.024 300706 45.728 46.774
Page 309: nbi31d00
50.15 5 69.15 1 93.15 51.15 12 75.15 1 103.15 52.15 5 76.15 1 104.15 53.15 2 77.15 4 105.15 LIBRARY SEARCH RESULTS Scan 2896 (44.041 min) of DATA:ACHEA09A.D MENTHOL-2 2 159.15 1 1 161.15 12 2 162.15 12 2 163.15 1 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: NICOTINE 0 7 9830 2: NICOTINE 0 236 9830 3: NICOTINE,ISOMER (SL 19D) 0 874 9100 4: PYRROLIDINE,2-ETHYL-1-METHYL- I 1156 8805 5: PYRROLIDINE,1-PROPYL- I 1155 8740 6: PYRROLIDINE,1-ETHYL- I 1150 8325 7: ANABASINE 0 498 8245 8: PIPERIDINE,2-ETHYL- 0 1137 8210 9: PYRROLIDINE,2,5-DIMETHYL- I 1151 8196 10: 6LUTARIMIDE,3-METHOXY- 0 767 8164 Scan 2696 (44.041 mtn) of ORTR:RCHER09R.0 100J,. .,~ ~2 .....,.. .~65 . .......~I B4. ..._ 1119 f~ 3 1/ 1 ~"100 100] e 42 1 4 / 2 \ Y7 NICGTINE 181 1 g 133 18 1 s4 / I n 0238 NICOTINE 84 119 199 f L~ 161 n k674 NICOTINE.I5OHER C5L 190] 100 55 \ 175 20~4 Ft100 50 42 L84 \ \ ~'50 ~~i i i ~ r- -r----^-~-----r io 40 60 80 100 120 140 160 180 200 MassiCharge T: null. Z: Scan 2893 (44.D02 min) of GRAPHICSCD Y: TIC of DATA:RCHEA09A.D IMS2) X: Set of 4 MS Scan 2896 (44.041 min) of DATA:ACHEA09A.D MENTHOL-2 m/z abund, m/z abund. m/z abund. m/ z abund. 28.15 12 54.15 3 78.05 6 106. 15 1 29.15 2 55.15 5 79.05 2 107. 15 1 30.15 2 56.15 1 B0.15 2 117. 15 4 37.25 1 57.15 1 81.15 2 118. 15 5 38.15 4 62.15 2 82.15 7 119. 15 9 39.15 14 63.05 6 84.15 100 120. 15 2 40.15 3 64.15 3 85.15 5 130. 15 4 41.25 10 65.05 8 89.05 1 131. 15 1 42.15 38 66.05 2 90.15 1 133. 15 28 43.25 2 67.05 2 91.15 4 134. 15 3 dd_15 7. RR.1CZ 1 99 Ir 7 1 AC 7C t
Page 310: nbi31d00
51.15 11 68.16 2 LIBRARY SEARCH RESULTS Scan 3941 (57.388 min) of DATA:ACHEA09A.D MENTHOL-2 Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAB lk Library Match Index # Quality 1: MYOSMINE 2: PYRROLE[1,2a]PYRAZINE,3,6-DIMETHYL- 3: BENZONITRILE,2-AMINO- 4: PYRIDINE,2-(1-PROPENYL)- (SBB 236D) 5: TETRALONE-1 6: BENZIMIDAZOLE 7: BENZIMIDAZOLE 8: PYRIDINE,3-CYANO-4-METHYL- (SWW 1000) 9: IMIDAZOC1,2a]PYRIDINE 10: IMIDAZO[1,2-a]PYRIDINE,2,3-DIMETHYL- Bcan 3941 (57:38B mtn) of 39~ 91 78 I , ddi iL .ni d 10 9664 1371 7520 1488 7029 643 6925 834 6875 95 6757 614 6731 275 6704 968 6598 924 6451 GRTR:RCHER09R.C1 r100 9 1 146 I) 6 II"`"'000yr' 010 MY05MINE 51 78 10,5 I 1 i 11 116 146 II PYRROLEC1,2a]PYRRZINE,8,6-[)IMETHYL- 3 51 1 0 4 116 ~frr'00 ~ I i ~~ ~ 1146 II M1466 BENZONITRILE.2-RMINO- 100 E100 63 64 E 50 ` / 91 11 B ~'S0 0 r ---+-~- / ~ €n 0 20 40 60 80 100 120 140 Masa/Charpe GRRPH]CSCD [MS2] T: null. Z: Scan 2928 (44,461 min) of Y: TIC of DATR:ACHER09R.D X: Sei of 4 MS Scan 3941 (57.388 min) of DATA:ACHEA09A.D MENTHOL-2 m/z abund. m/z abund. m/z abund. m/ z abund. 28.15 30 43.15 11 65.05 15 105. 15 18 ut 32.05 8 50.15 17 76.15 7 118. 15 100 ~. 38.25 9 51.15 28 77.15 11 119. 15 11 w m 39.16 31 52.15 11 78.05 26 145. 15 57 w 40.15 18 62.15 7 91.15 15 146. 15 64 V F-. V 41.15 28 63.05 15 104.15 10 147. 15 8 m 42.15 19 64.15 13
Page 311: nbi31d00
LIBRARY SEARCH RESULTS Scan 2790 (42.E41 roin) of DATA:ACHEA0IA,D LIGHTS EXTRACT Librarj filc: DATA:T02ACCO.L Library namc: TOBACCO AND SMOKE COMPONENTS CAS # 1: 9UTAP1-1,3-DIOL 0 2: ACETIC ACID,2-HYOROXY,2-HOPROP ESTER 0 3c OXAZOLIDI":E-2,4-DIONE,S-METHYL- 0 4: BUTYP,ALDEHYDE,3-HYDP,OY,Y- 0 5: TP,IOXAME-l,3,5, 2,4,E-TRIMETHYL- 0 6: DIITAAIDr:E-2 , 3-HYDP,OXY- ( ACETOIPJ ) 0 ' OCTAMOL-2 0 °: LACTIC ACID 0 9: PEPlTAPJE-1,3-DICL 0 10: 1,2-000PANEDIOL 0 r I Scan 2790 (42.641 m1n) oP ORTR:RCHER01R.0 Library Match Indcx # Quality 1752 E03E 721 7510 1725 7401 1414 7251 1479 7051 1743 6830 168s 6780 E58 s701 1E37 6544 149 6419 I 160J1~~ 114 59 g9 ~"106 I I IIIII ~ II"00_ ~ i tt1?52 EIJTRM-I,3-DIOL 106 _ ~ ]l 72 ~102 i ~ H~~ 1 29 II 1~3 ! +1y1 a ®721 RCETIC ACI0,2-HYORDXY,f-HOPRDP E5TER 100'~ ~ , 59 7n 90 r166 lie `!d3 I LL pJ I1 II~ 15 1~ I 1~ "^~. I ' Iki7e5 utiRIuLIGINE-e,4-DIDWE.5-METHYL- i .450N I~. 115 1013 i 50 ~I 26 I 163 70 56 DD 4E 50 G0 7L7 00 ^.0 12p 11E ~ Mac~:Chargc T: null, 2: Scan 1949 (31.933 min) of GnAPH1CSCD i: T1C uf "vATA:ACHEADIA.D LMS'LJ X: Set of 4 MS Scan 2790 (42.E41 min) of DATA:ACHEA0IA.D LIGHTS EXTRACT r;z abund. m/z abund. mlz abund. r;;z abund. 2°,05 E0 32.05 22 42.l5 39 45.05 100 29.15 5; 39,15 21 43.16 44 59,05 39 31,.5 67 41,15 22 44.05 38 89.05 33
Page 312: nbi31d00
LIBRARY SEARCH RESULTS fican 193? (31.?£1 ro:n) of DATA:ACHEAOIP..D LIGuTS E,v,TRACT Library filc: DATA:T09ACCO.L Library nn-c: TOBACCO AND SMOKE COMPONENTS 1: LACTIC ACID Z: ' °-PP,OPAP:ECIOL 3: OCTANOL 2 4: FOP,MAMIDE 5• 6:JTANcfJTnL-O ~' L ~ V L, J E: TRICXAME-1,3 5 2,4,6-TRIMETHYL- ?: LACTIC ACID, ETHYL ESTER P.: 13UTA":-I 3-DIOL 9: 13:1TANONE-2 , 3-HYDPOY.Y ( PCETOIP: ) 10: Bl;TA":ETRIOL-1 ,2 3 CA9 ~ L:brary Match Indcx : Quality 0 650 6500 0 149 936? 0 16°£ °339 0 755 °321 0 837 8316 0 1479 °312 0 ?31 8260 0 I?52 7042 0 1743 7711 0 93° 7512 Bcan 1937 (31.7B1 mtn) of ORTR:RCHER01R.0 in0-~ 28 ~., r100 I nJI IIlI II 44 h 4S fi£5£ LRCTIC PCID ~~ (t01a 4 ~5 *149 1,2-PROPRNEDIpL 43 ~\ 76 II, ! Nisns QCTnNDL-2 16E - 43 R9 ~'16F7 50~ 45' ~ 97 ~{t{E''50 ~u f' ' IJ . t; I0 413 Co oE :ao .~© 142 Ma.¢:Charjc__ ___ G"nAFn1CSC0 IMSZJ T: null. Z: TIC of DRTA:ACHEADSR.D Y: TIC of DAT"n:RCHEADIA.D X: Set of q MS Scan 1937 (31.7°1 min> o." DATA:ACHEA0IA.D LI£HTS EXTP.P,CT r,:z abund. N:z abund. n!z abund. N/a abund. 2°.15 41 31.16 2? 43.15 26 45.15 100 49.15 34 3Y.15 23 44.1E 22
Page 313: nbi31d00
44.15 5 77.05 4 105.05 5~.~5 5 70.05 7 10E.15 LIBRARY SEARCH RESULTS Scan ~852 ;43.43° min) of DATA:ACHEAOIA.D LIGHT~ EvTRACT L:brar; filo: DATA:TOBACCC.L Librarr namc: TOBACCO AND SMOKE COMPONENTS CAS k 1: NICOTINE 0 ': NICOTIP:E 0 3: NICOTINE,ISOMEP, (SL 190) 0 1; PYRPDLIDINE,2-ETHYL-I-METHYL- 1 5: PYRP,OLIDINE,1-PP,OPYL- I 6: ANA°ASINE 0 7: PIPEP,IDIP:E,2-ETHYL- 0 9: GLUTAP,IMIDE,3-METHOXY- 0 9: PYRP,OLIDINE,I-ETHYL- I 10: PYRROLIDINE,2,5-DIMETHYL- I 3 162.10 1£ 2 163.10 2 Library Match Indcx : Qualitr 7 9953 236 9953 874 9084 1156 8834 1155 8598 498 8467 1137 °295 767 8248 1150 8189 1151 8054 Bcan 2852 (49.489 mtn) of ORTR:RCHER01R.0 100, 42 ES I\. 11C 159 18E ('100 }I / JR4 / I u ff7 NICOTINE 119 S~y 161 !B4 r L~ u M296 NICOTINE 100, A i, liy j 9 1 6674 NICOTINE.ISONER 100~ 44 N 4 161 11 (5L 190) 175 E04 100 50 1c0 102 C000 50~ j j '64 / Gi , j r ' r^^-^r^-^-'-r 40 u0 q:. 100 1113 140 Maa: Chnrgc GftRFHICSCD L11SZ1 T: noll. Z: Scan 2835 (43,:18 min) of Y: TIC vf DRTA:ACHEADI"n.D X: Set of 4 MS Scan 28511 (43.43£ min) cf DATA:ACHEAOIA.D LIGH?S EXTP,ACT m/: ebund, m/z abund. abund. m/ : abund, 29.A 5 1£ 4 3.15 4 65.05 0 92. 05 7 29.2 5 3 4 4.15 8 77.05 S 117. 10 4 30.1 5 4 5 0.15 5 7O.©5 6 118. 10 7 32.0 5 A 5 7.15 10 81.05 3 119. 10 9 3V.1 5 4 5 3.05 3 82.05 E 130. 10 5 39.0 5 72 5 5.05 6 84.05 100 133. 10 30 40.1 5 3 E 2.95 5 95.05 E 161. 10 15 41.1 5 10 6 4,15 3 90.95 4 162. 10 15 42.1 5 31
Page 314: nbi31d00
Data file: DATA:ACHEA03A.D File type: GC / MS DATA FILE Nane Info: MENTHOL EXTRACT Misc Info: Operator : JNS Date : 12 Aug 86 Instrment: MS 5970 Inlet : GCy Sequence index : Als bottle num : Replicate num . 6:23 pm 1 3 1 TIC of DRTR: RCHER63R. 0 M n u c 4 B.BES a c a 6.IdE5 ¢ j 4.6E5I 40 T1 me ~ 50 BP Cmin.] m np~ m NS ut mn 70 BO 90 100 2.0E5~ o~r 1D 20 30 GRAPHICSCD [M32I TIC of DATA:ACHEA03A.D MENTHOL EXTRACT T: Set of 4 MS Z: Scan 7167 (98.452 min) of Y: TIC of DRTA:RCHERD2A.D X: TIC of DRTA:ACHER03R.D Peal:# Rat Time Type Width Area Start Time End Time 1 3 3.606 BV 0.090 36406434 33.435 33.626 2 3 3.640 VU 0.125 44732730 33.626 33.806 3 3 4.053 VV 0.321 379669801 33.806 34.566 4 3 4.573 VV 0.164 30594299 34.566 34.999 5 3 5.225 PV 0.023 178539 35.198 35.249 6 4 3.250 PV 0.066 17813392 43.105 43.261 7 4 3.273 VV 0.114 24428989 43.261 43.426 8 4 3.444 VV 0.106 17680603 43.426 43.651 9 4 3.947 VU 0.342 374327231 43.651 44.724 10 4 4.740 VV 0.053 405B363 44.724 44.791 11 4 4.804 VV 0.046 2073167 44.791 44.846 12 4 4.876 VV 0.050 2012483 44.846 44.944 13 8 3.SB3 VV 0.024 151474 83.564 83.606 14 86 .627 PU 0.015 127407 86.603 86.641 15 8 8.309 VV 0.029 306523 88.271 88.345
Page 315: nbi31d00
44.05 4 E6.95 2 104.05 50.15 5 ?E.O5 1 !05.05 5!.!5 !0 77.05 4 106.05 LIBRARY SEARCH RESULTS 3 1E2.1fl(] 16 L 163.!U L 2 Scan 2933 (44.407 rin) of DATA:ACHEAOIA.D :.IC'HTS EvTRACT Librarr filc: DATA:TCEACCC.L Library narc: TOBACCO AND SMOKE COMPONENTS 1: NICCTIME 2: NICCTINE 3: NICOTINE,ISOMER (SL 190) 4: PYRP,DLIDINE,2-ETHYL-I-METHYL- 5: PYP,RCLIDINE,1-PPOPYL- E• ANA°ASINE 7: PIPEP,IDINE,2-ETHYL- E: PYRRCLIDINE,1-ETHYL- o: 6LUTAP,IMIDE.'-METHCYY- ~ 10: PYRP,CLIDIP:E,2,5-DIMETHYL- 9can 2939 1n0~ 42 0 e BJ.,, ,'.., „! 4 CAS # Library Match Indcx # Quality 0 7 9D74 0 23E 9874 0 874 8890 1 1156 9607 1 1!ES 9442 0 498 9394 0 1!3? 8082 1 1150 9041 0 767 8036 1 1151 7910 (44_4B7 mtn) cf DRTR:RCHERBIR.O I\ l.C 133 1Rt ~ ~ R4 / n I M7 HICOTINE ~ \ 119 li3 161 84 M236 NICOTINE i • ilJ ~3 1 ~I. *B74 NI CuTIiJE. ISGMER 84 .. ~ . .,I . !. CGf GRn"PHiCSCA aa T: null. Z: Scan 2KII5, (44.123 ®ir.) of Y: TIC uf "vRTA:ACHEADIR.D LM5'L1 X: Set of 4 MS Scan 2933 (44.491 rin) of DATA:ACHEA0IA.D LIEHra EvTRACT n/z abund. nJz abund. r/z obund. m/z abund. 2°.OS 14 44.15 5 77.05 4 105.15 3 29.05 5 50.15 4 78.05 6 117.20 4 30.05 7 51.15 /2 79.05 3 11°.10 6 32.05 A 52.05 4 92.fl5 ? 119.10 10 30.15 4 54.15 7 °4.05 100 130.10 4 39.05 13 55.05 E 85.15 6 133.10 33 40.15 5 E3.05 ? 91.15 4 134.20 4 4!.!5 9 64.05 4 92.05 10 161.10 19 42.15 77 E5.05 9 104.05 3 !E2.lfl 17 4 3.05 2
Page 316: nbi31d00
LIBRARY SEARCH RESULTS Scan 3031 ;45.?45 nin' cf DATA:ACHEROIA.D LISHTS EXTRACT Librcr~ fi1c: DRTA:TOEACCC.L Library namc: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Indcx # Ouality 1; nJTrnrrnic 0 7 8632 ..... ...~ `. fJTrnTT JE n ~3 067!O 0 6 „ ..~ 3: "JICCTIPJE,ISCMER (SL !9D) 0 874 8014 4: PYP,RCLIDIME,1-PRDPYL- 1 1155 7052 5: PYRP,OLIDIME,2-ETHYL-I-METHYL- I 1156 7663 6: 6LL'TRRIMIDE,3-METHOXY- 0 767 761? 7: PYRP,CLIDIME,1-ETHYL- 1 l150 7426 0. PYPRCLIDIME,2,5-DIMETHYL- 1 1151 7379 9: PIPEP,IDIME,2-ETHYL- 0 1137 7367 !0: AMA°ASIME 0 498 7270 Scan 3031 C45.745 m1n7 af ORTR:RCHER01R.0 1013 I 1001 d? (~J I ~ 119 ~ 9 152 R4 1 I II 47 NICOTINE • i8 161 k8s6 NICOTINE \` l l g ~ 9 0874 ivICuTINE, ISGMER 17C ~ 55 50~ 4i ~ g ~4 dt,d 40 CQ 00 1©0 120 140 Ha.o: Charac T: Z: GR"nFHiC5C0 Y: Lf9S'LJ x: 181 i 11 (5L 1gu) 175 204 1©ID 50 R ICC 1CU 2C0 null. Scan 2971 (44.977 minO of T1C of D"nTR:RCHEADIR.D Set of 4 MS Scan 3031 :45.?45 min) of DRTR:RCHEAOlA.D LIGHTS EXTRACT ml: abur,d. m:z abund. m/z obund. m;a abund. 23.15 53 41.:5 17 61.05 15 '33.10 28 32.05 26 42.05 35 64.05 100 161.10 15 39.15 17 44.15 I5 119.:.0 14 162.10 17
Page 317: nbi31d00
LIBRARY SEARCH RESULTS Scan 297J ;44.977 nin) of DATA:ACHEA©IA.D LIGHT9 EXTRACT Library fi1c: DATA:TOEACCD.L LSbrarr naxc: TQBACCQ AND SMQKE COMPONENTS CAS >E Libra Indcx ry Match # Quality 1: MICDTI4E 0 7 9594 2: PJICQ?IME 0 236 9694 -7: MIOOTIME,ISDMER ;SL 19D> 0 874 8842 4: PYP,ROLIDIME,2-E1'HYL-1-METHYL- 1 1156 8723 5: PYP,ROLIDIME,I-PP,OPYL- ! t155 8357 5: ANABASINE 0 498 8301 7: PIPEP,IDI"JE,2-ETHYL- ~ 1137 8!26 8: GLUTARIMIDE,3-METHQY.Y- 0 767 8079 9: P,vRROLIDIME,I-ETHYL- ! 1150 7960 10: PYRRQLIDIME,2,5-DIMETHYL- 1 1151 7026 f (44.977 mtn) of ORTR:RCHER01R.0 I\ 1.7 198 IR9 -- . , Scan 2971 wu~I 42 Ce 13 Ja aJ i .i. . I / 20 I 4[ u b- b I; 1ae~ ,2 i u 0 ll ~ t7 NICpTINE \ \ 119 1 ~ 161 84 0236 NICOTINE IB6^ 11J ~ 161 n ki"s74 idICOTINE,ISDFiER SSL i567 41` / 84 1~\ 2506 40 CE 0ID 1Ec 1 Z E 142 106 100 CCM I Na •Charmc T: null. Z: Scan 2958 (44.809 nin) or GRnPH1CSCu Y: TJC oT "vRTA:RCWRi.1R.D LMS'l.J X: Set of 4 MS Scan 2971 f44,977 °1nY of DATA:ACHEAL"tA,D LIGHTS EvTRACT *;a abund. m/z abund. n/: abund. */ : abund. 28.05 25 41.15 9 55.05 5 92. ©5 7 29.15 7 42,05 29 65.05 9 118. 20 8 44.15 5 78.05 6 119. 20 0 31~..V5 IY 50.05 6 82.05 8 133. 2© 28 38.©5 5 51,©5 10 84.05 100 1611 10 16 39.L5 12 52.05 6 85.05 6 162. 10 19
Page 318: nbi31d00
LI°RARY SEARCH RESULTS Soar; 2958 (44.9©8 min) of DATA:ACHEAl31A.D LI6HTS EY,TRACT Library filc: DATA:TOEACCO.L Library namc: TOBACCO AND SMOKE COMPONENTS CAS # Librarr :ndax # Match Quality 1' MICOTINE 9 7 9970 2: NICOTINE 0 236 9970 3: NICOTIM~ ISOMEP, fSl 19D) 0 974 9046 4: PYRROLIDINE,2-E THYL-1-METHYL- I I156 0701 5: PYRPDLIDIP;E '-P I ROPYL- 1 1155 8612 6: A"JA6ASIME 0 498 8418 7: PIPEP,:OI"JE,'-ET ~ HYL- @ 1137 8245 ' ' 9 PYP,RCLIDINE -E , THYL- I 1150 8203 9• 6LLTAPIMIDE '~-M I ETHOXY- © 767 0198 10: PYRP,OLIDINE,2,6 -DIMETHYL- I 1151 8Q7© r ~ Bcan 2956 (44.606 m1n) of qRTR:RCHER01R.0 ~ rt00 4 2 6 11: ~8 162 OJL., ' R4 I .1. II ~ ,oa, ~ i!7 HICOTINE ~ 1 9 . ~ 61 r]om ~ ia- I ° ~ ~ I. ' L. Iro N236 NICOTINE 1081 40 N 133 f100 ~ ll•J i61 S mJ I I 6ll ti S 674 N ICGTIi JE. ISGHER (SL 150) © 5E~ 42 ~ 4 1\i 75 ® 2~~ 124 40 Cl; 06 160 120140 0 1u^0 il)D 2~0 Ma.a: Charya GR"nPnICa~O IMSZJ T: null. Z: Scan 2937 (44.539 min) of Y: TIC vf DRTA:RCHEA0IA.D X: Set of 4 MS Scar 2959 (44.°0e min) of DATA:ACHEAOlA.D LIrHTS EX?P.ACT m!z abund. m/z abund. m/z abund. ml z abund. 29.1 5 19 4Z.05 33 77.L5 5 118. 2© 6 ~9.l 5 5 43.15 4 78.C5 5 119. 2© 8 31.1 5 4 43.95 7 82.05 8 130. 10 6 32.1 5 7 5©.Z5 4 84.05 100 133. 2© 29 38.1 5 4 51.©5 13 85.05 6 134. 2@ 5 39.I 6 12 62.05 7 9l.05 4 161. 10 17 39.9 5 6 63.35 E 92.(A5 8 162. 10 17 41.1 5 11 65.©5 7
Page 319: nbi31d00
LIBRARY SEARCH RESULTS Scan 2899 544.044 min) of DATA:ACHEA0IA.D LIGHTS EXTRACT Librc.ry .'ilct DATA:TOBACCD.L Library namc: TOBACCO AND SMOKE COMPONENTS 1: NICOTIf:E I : Niv.niTINE 3: NICOTI":E,ISOMER (5L 190) 4: PYRROLIOINE,2-ETHYL-I-METHYL- 5: PYRRDLIDINE,'-PROPYL- 6: ANABASINE 7: PIPERIDINE,2-ETHYL- o: PYRROLIDINE,1-ETHYL- 9: BLUTARIMIDE,3-METHOXY- 10: PYRROLIDINE,2,5-DIMETHYL-- ie01 I tF? NICOTINE ! ~ 119 161 IBa IP286 NICOTINE \• 11 `! ~ 5 I Q1 il Ii k674 NICOTINE.I5PFIEk lE~-i 55 •~ 64 F 4'J Ca O.n. GRAPHICSCG LMSY1 1.7.^. 1L'0 140 Masm ; Charpc 16i i5L 150) 175 E134 €1©CJ `` ~`~50 ~-r-^"~--'--~---~-~~ G loa 1ca 203 T: null. Z: Scan 2855 (43.476 ain) cf Y: TIC of DATA:ACHERaiA.D Xi Set of 4 MS Scon 2899 (44.044 min) of DATA:ACHEA01A.D LI6HT5 EXTP,ACT mIz sbund. m/z abund. m/z abund. m/ z abund. 28.1 5 11 5 3.05 2 79.05 2 117. 20 5 29.1 5 3 5 4.05 3 80.05 2 118. 10 7 30.1 5 2 5 5.05 7 81.05 2 119. 10 10 32.0 5 2 5 6.05 1 82.05 6 120. 10 2 38.1 5 3 6 2.05 2 84.05 100 130. 20 4 39.1 5 13 6 3.05 6 85.05 6 131. 10 2 40.1 5 3 6 4.05 3 88,95 1 133. 20 33 41.1 5 9 6 5.05 8 90.05 1 134. 20 4 42.1 5 33 6 6.05 2 91.05 4 145. 20 1 43.1 5 2 6 7.05 2 92.05 6 159. 10 2 44.1 5 3____-6 8.05 1 93.15 2 161. 10 16 CAS tt Library Match Indcx k' Quality 0 7 9934 0 236 9934 0 874 8959 1 1156 8697 1 1155 8529 0 498 8431 0 1137 8166 1 1150 8124 0 767 8119 1 1151 7992 Scan 2699 (44.044 mtn) of ORTR:RCHERB1R.t] 42 C` i\ 113 f 3 162 l IR4 / ~
Page 320: nbi31d00
LIBRARY SEARCH RESULTS SCa- 2°35 (43.218 min) of DATA:ACHEA01A.D LISHTS EXTP,ACT Librarr filc: DATA:T08ACCC.L L:'br.-,rY na-c: TCBACCC AND SMOKE COMPONENTS 1: "lICOTINE 2: MICCTIME 3• MICCTII':E,ISOMEP (SL 19D; 4: PYRROLIDIME,2-ETHYL-I-METHYL- 5. PYRRCLIDIME,'-PRCPYL- 6: A":AEASIME ? PIPEPIDINE,2-ETHYL- 9 6LUTARIMIDE 7-METHCXY- I 9• PYRP,CLIDIP:C I-ETHYL- 10; PYPROLIDI":E,2,5-DIMETHYL- CRS # Library Matoh Indox R Quality 0 7 9911 0 236 9911 0 874 8933 1 1156 8689 ! 1155 8480 0 498 8415 0 1137 8158 0 787 8112 1 1150 8085 1 1151 7953 Scan 2635 (43.216 mtn) of DRTR!RCHERDIR_D I iaa 42 G5 ~, 11C 133 191 ... ..~.A.. .e..~ .~~L. ~~... . ~~. .~.. ~.~. ~.6 .II. 1 R7 NICCTINE ~ 1Dn~ 4 e ~ 119 lj3 161 Nu C' 1~ 0236 NICOTINE 1ma r ISaD ~ ~ 4? I ~ li`J ~ 3 161 QJ 6; d I, ii LD iP874 idICGTINE.IStlNER 1DD- 54 ~ SD~ 4i r1 84 -------~- 4.. CD nD 160 1Z" 0 140 ' Mas •Cha^g c iSi. i5GJ 175 204 100 ~SD D 1CD 20D T: null. Z: Scen 2?0% (42.641 min) cf G"nAPHiCSCG Y: TIC of DRTR:ACHERO1R."v LMS'lJ X: Set of 4 MS Scan 2°35 (43.218 min) of OATA:ACHEA0IA.D LIC-,NTS EVTRACT m/a abund. nJz abund. m; z abund. m; z abund. 28.0 5 '.2 51.15 79.05 3 107. 15 1 29.1 5 3 52.05 5 80.15 2 117. 20 5 7A.I S ~ 53.05 2 81.05 2 118. 20 6 32.0 5 Z 54.05 3 82.05 6 119. 10 9 3?.1 5 ! 55.05 4 84.05 100 120. 20 2 39.1 5 Z £2.05 Y 85.05 6 130. 10 4 39.1 5 11 53.05 5 29.05 1 131. 20 2 40.0 5 3 64.05 4 91.05 4 133. 10 33 41.1 5 9 65.05 8 9Z.35 7 134. 20 3 42.1 5 32 66.05 3 93.05 2 159. 10 2 4 3.I F 1 R6_9S 7 1Ad_1S 'A 19Zt tof 10
Page 321: nbi31d00
L1£RAPY SEARCH RESULTS Scan 1949 (31.933 min) of DP,TA:ACHEAflIA.D LIGHTS EXTRACT L'brary filc: DATA:TOBACCO.L L'.brary namc: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Indcx # Quality I: PP.OPANEDIOL-1,3 0 1627 7167 2: PYRRDLE-2-CAR°OXAMIDE 0 1567 6943 3: OXAZOLIDINE-2,4-DIONE,S-METHYL- 0 1725 £939 : DECA^:AL 0 1561 6700 5: AZE?IDINE 0 112° 6496 6: PYP,IDINE,2-METHYL-S-ISOPP,OPANOL- 0 1587 6157 7: OCTANE-2,3-DIONE D 1558 6081 °: ACRYLIC ACID,3-f2-cURYLI-2-Mo-,Et ESTER 0 1533 6040 o; hIETuYL ,n,^1INE,N-METHYL- 0 1285 6005 10: CYCLOHEY,ANE-',4-DICNE 0 t5££ 5£°D ~ Bcan 1949 C31.933 mtnJ of ORTR:RCHER01R.0 Gw'~ ~ r16q t` ii4 "`000 1 IB I 4i '!18?' PP.OPRPIEDIOL-1, ° ll 01567 PYRROLE-2-CRRBOXRMIOE 44 6S fi6 94 110 rtBm i ~I II 1 lil7e5 VAFIZVLI4IIYE-L!, 4-OIOiJE, 5-YIETHYL- 115 r1©0 ~ ~ 10 I 0 ^c6 ~p3 f o - ~ I r ~-~ - , 00 43 5fl CO 76 00 OS7 t~0 11© Mnca: Cha~.c ------ Gnn"rlHJCSCC 1M5'LJ ~50 0 T: null. Z: Scan 19?7 (31.781 rin) of Y: T3C uf DnTR:fiCHEADifi.D X: Sct of 4 MS Scan 1949 t3l.o33 rin) cf DATA:ACHEADIA.D LIGHT£ EXTP,ACT n/: ahund. n:: „bund. 28.DJ IDD 31.15 41 29.15 49 32.15 5£ r,lz obund. r/z abund. 44.15 32 45.15 56
Page 322: nbi31d00
LIBRARY SEARCH RESULTS Scan 2083 (33.642 min) of DATA:ACHEA03A.D MENTHOL EXTRACT Library file; DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: MENTHOL 0 132 7969 2: LINOLEIC ACID, METHYL ESTER 0 1741 7366 3: CAMPHOR-D 0 1547 7306 4: NONA-2,4-DIENAL 0 1447 6510 5: OCTEN-6-AL,3,7-DIMETHYL- 0 1453 6496 6: PYRAN-2-ONE(2H), 5,6-DIHYDRO-4-ISOPROPYL 0 1676 6357 7: PHYTOL 0 55 6207 8: BENZOFURAN-2-ONE-3H, HEXAHYDRO- 0 1707 6130 9: HEXA-2,4-DIENAL 0 1437 6108 10: LINALOOL 0 1556 5946 Scan 20B3 (33.642 mtn) of ORTR:RCHER03R.0 160 123 0132 MENTHOL 120 lI 23 0J ~3 I ~ ~l ~I ~ I 100 ~ 01741 LINOLEIC RCIO. METHYL ESTER ~ 100 r`~ ~ 109 r100 'IIfl3 ~ ¢ [' 7 0 I 111 II 1 ,"" /k1547 CRMPHQR-0 109 152 F100 ,~i 1 111 5 ~ ,% ~50 r r rL r r ^"'r 0 50 100 150 200 250 300 MassiCharge T: null. Z: Scan 2D80 (33.604 min) of GRAPH]CSCO Y: TIC of DATA:RCHEA03R.D [H'S'2I X: Set of 4 MS Scan 2083 (33.642 min) of DATA:ACHEA03A.D MENTHOL EXTRA m/z CT abu nd. m/z abund. m/z abund. m/ z abund. 28.15 26 44.05 10 68.15 19 85. 15 9 29.15 56 45.15 5 69.15 40 93. 15 7 30.25 4 53.05 20 70.25 23 94. 25 9 31.15 14 54.15 12 71.15 100 95, 15 62 32.15 7 55.15 76 72.05 6 96. 15 27 38.05 4 56.15 28 79.15 6 109. 15 13 39.15 39 57.15 45 80.25 14 110. 15 7 41.15 100 57.95 5 81.15 85 123. 25 24 42.25 18 65.15 5 82.15 38 138. 25 16 43.15 56 67.15 46 83.15 12
Page 323: nbi31d00
LIBRARY SEARCH RESULTS Scan 6238 (86.628 min) of DATA:ACHEA03A.D MENTHOL EXTRACT Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: PYRROLE-2-CARBOXAMIDE 2: DECANAL 3: PROPANEDIOL-1,3 4: ACRYLIC ACID,3-(2-FURYL)-2-Ma-,Et ESTER 5: AZETIDINE 6: OXAZOLIDINE-2,4-DIONE,S-METHYL- 7: PYRIDINE,2-METHYL-S-ISOPROPANOL- 8: OCTANE-2,3-DIONE 9: CYCLOHEXANE-1,4-OIONE 10: CYCLOPENTANONE,2,5-DIMETHYL- 1567 7846 1561 7688 1627 7401 1533 7211 1128 7179 1725 7066 1587 6930 1558 6732 1566 6663 1509 6413 Scan 6238 (86.688 mtn) of pRTR:RCHERp9R.p lpp'j''~., \ 45 r30p pJl II26 11 IIDIDIDI Ipp~ " 0 f p~ J 6 k1567 PYRROLE-2-CRRB0XR11IDE 40 66 94 a 01581 DECANAL c ~ 3 1pp 1.,~ 41 57 62 rg106 a p I 28 ¢ If`lfff tk1627 PRDPRNEpIDL-1.8 1p0 '~. 57 1pp 5p 26 43 II ~'Sp 0 i FF' 313 40 50 60 70 84 9p 1013 110 Mass/Charge GRRPHICSCO [MS2] T: nu11. Z: Scan 5999 (83.582 min) of Y: TIC of DRTR:RCHER03R.D X: Set of 4 MS Scan 6238 (86.628 min) of DATA:ACHEA03A.D MENTHOL EXTRACT m/z abund. m/z abund. m/z abund. m/z abund. 28.15 100 31.35 26 44.45 24 45.15 42 29.15 33 32.05 30
Page 324: nbi31d00
LIBRARY SEARCH RESULTS Scan 2956 (44.804 min) of DATA:ACHEA03A.D MENTHOL EXTRACT Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: NICOTINE 0 7 9957 2: NICOTINE 0 236 9957 3: NICOTINE,ISOMER (SL 19D) 0 874 9038 4: PYRROLIDINE,2-ETHYL-I-METHYL- 1 1156 8898 5: PYRROLIDINE,I-PROPYL- 1 1155 8558 6: ANABASINE 0 498 8485 7: PIPERIDINE,2-ETHYL- 0 1137 8288 8: 6LUTARIMIDE,3-METHDXY- 0 767 8241 9: PYRROLIDINE,1-ETHYL- 1 1150 8151 10: PYRROLIDINE,2,S-DIMETHYL- 1 1151 8015 at Saan 2956 (44.604 m1n) of ORTR:RCHEA03R.0 42 ES \ 119 133 162 n~ i .~ B4 .~ .I n 42 I k7 NICOTINE 119 s 3 16 IB c 3 4 / P 6236 NICOTINE 100 k674 NICOTINE,ISOMER (SL 190) 55 \ 175 Q04 100 50 ~ ~ ~64 ~ 50 1 000 r ^r I 0 40 60 60 102 120 140 160 180 200 Masc/Charge T: null. Z: Scan 2951 (44.739 mia) of CRAPHICSCD Y: TIC of DATA:ACHER03A.D [H52) X: Set of 4 MS Scan 2956 (44.804 min) of DATR:ACHEA03A.0 MENTHOL EXTRACT m/z ab und. m/z abund. m/z abund. m/ z abund. 28.15 22 42.15 30 78.05 6 118. 15 6 29.15 6 51.15 10 82.15 8 119. 15 10 32.05 7 63.05 6 84.15 100 130. 15 6 38.05 5 64.15 5 85.15 6 133. 15 31 39.15 10 65.05 8 91.15 5 161. 15 14 41.15 9 77.15 5 92.05 7 162. 15 16 1
Page 325: nbi31d00
53.05 18 72.05 5 94.25 9 139.25 3 54.15 11 Scan 2155 (34.575 min) of DATA:ACHEA03A.D MENTHOL EXTRACT Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: MENTHOL 0 132 8477 2: PHYTOL 0 55 7398 3: CYCLOHEXANE-1,2-DIOL,1,3,3-TRIMETHYL- 0 1629 7363 4: LINALOOL 0 1556 6975 5: IONONE,TETRAHYDRO- 0 1503 6959 6: CAMPHOR-D 0 1547 6866 7: 8ICYCLO[440]OECANE,1559-ME-9-HO-10-OXO- 0 1747 6799 8: LINOLEIC ACID, METHYL ESTER 0 1741 6791 9: MARIOLIDE, DIHYDRO- 0 1745 6755 10: TERPIN HYDRATE 0 1589 6708 LIBRARY SEARCH RESULTS Scan 2155 (34.575 min) nf ORTR:RCHER03R.0 10 ILp6 .~'q d~'tl ~g 109 123 r100 41 u c N 43 0132 MENTHOL ~5 I 1' 4 p M 655 PHYTOL c 3 ~ ¢ 11313 50 0 #1629 CYCLOHEXRNE-1,2-OI0L.1.3.3-TRIMETHYL- 55 F160 43 / 1 E2 lil 127 t FS0 ~------•k e 40 EB E0 1130 120 Marc/Charpe T: null. --l~ Z: Scan 2115 (34.057 min) of CRRPHICSCO Y: TIC of DATA:RCHEA03R.D [MS2I X: Set of 4 MS Scan 2155 (34.575 min) of OATA:ACHEA03A.D MENTHOL EXTRACT m/z abu nd. m/z abun d. m/z abund. m/ z abund. 28.15 27 53.15 20 69.15 38 85. 15 10 29.15 47 54.25 12 70.25 20 94. 25 10 31.15 11 55.15 65 71.15 100 95. 15 59 39.15 47 56.15 25 80.15 18 96. 15 21 41.15 98 57.05 46 81.15 89 109. 25 12 42.25 28 67.15 47 82.15 43 123. 25 32 43.15 69 68.15 15 83.15 12 138. 15 15 44.15 13
Page 326: nbi31d00
LIBRARY SEARCH RESULTS Scan 2115 (34.057 min) of DATA:ACHEA03A.D MENTHOL EXTRACT Library file: DATA:TOBACCD.L Library name; TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: MENTHOL 0 132 8324 2: PHYTOL 0 55 7504 3: NEOPHYTADIENE 0 1601 7091 4: CYCLOHEXANE-1,2-DIOL,1,3,3-TRIMETHYL- 0 1629 6955 5: LINOLEIC ACID, METHYL ESTER 0 1741 6872 6: PENTADECANAL 0 1454 6592 7: CAMPHOR-D 0 1547 6592 8: LINALOOL 0 1556 6591 9: TRIDECANAL 0 1478 6554 10: TERPIN HYDRATE 0 1589 6519 Scan 211 5 {34.657 m1n) oF ORTR:RCHER03R.0 0 16 ~ 100 ]l 41 i J 123 136 ''~ m ,. 1 . k1 92 MENTHOL ifdO ~, 1 100 J 43 I d 5 ~ ~1 ry I .,., 95 123 L- 13B ~ ~ 6 l ! 1 1 I l,~ /655 PHYTOL 3 100 r1~0 ~ , 95 123 _ ] e 43 I &1601 NE6PHYTROIENE 100 / fI 82 95 _-•- 123 -- FtOa 50~ 43 s7 9 ~. 50 0 40 60 60 MassiCharme 100 T 120 T: null. Z: Scan 2083 (33.642 min) of CRRPHICSCO Y: TIC of DATA;ACHERD3R.D CMS27 X: Set of 4 MS Scan 2115 (34.057 rin) of DATA:ACHEA03A.D MENTHOL m/z EXTRACT abu nd. m/z abund. m/z abund. m/ z abund. 28.2 5 13 55.1 5 66 77.15 5 95. 15 62 29.1 5 51 56.1 5 28 79.05 6 96. 15 24 31.1 5 11 57.0 5 45 80.25 15 97. 15 4 32.1 5 3 58.0 5 4 81.15 85 99. 15 3 39.1 5 42 59.1 5 3 82.15 36 109. 15 11 41.1 5 100 65.05 5 93.15 14 110. 15 8 42.2 5 18 67.15 48 84.15 4 111. 25 2 43.1 5 63 68.15 15 85.15 7 112. 25 2 44.1 5 13 69.15 37 86.15 3 123. 15 29 45.1 5 5 70.25 20 91.15 2 124. 25 3 1.1 5 4 71.15 98 93.15 5 138. 25 1R
Page 327: nbi31d00
LIBRARY SEARCH RESULTS Scan 2206 (35.226 min) of DATA:ACHEA03A.D MENTHOL EXTRACT Library file: OATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: DCTANE-2,3-OIONE 0 1558 8699 2: DECANAL 0 1561 8336 3: PYRIOINE,2-METHYL-5-ISOPROPANOL- 0 1587 7633 4: HEXANOIC ACI0,4-METHYL-S-OXO- 0 1529 7544 5: PYRROLE-2-CARBOXAMIDE 0 1567 7240 6: AZETIDINE 0 1128 6732 7: CYCLOPENTANONE,2,5-DIMETHYL- 0 1509 6696 8: ACRYLIC ACI0,3-(2-FURYL)-2-Ma-,Et ESTER 0 1S33 6470 9: OXAZOLIDINE-2,4-DIONE,5-METHYL- 0 1725 6331 10: FURANONE-2(3H), 4,5-DIHYDRO- 0 1806 6222 Bcan 2206 (35.Y26 m1n) of ORTR:RCHER03R_0 100 \ 71 ~100 0~~ ~\z6 11 I/fl1 IF155B OCTRNE-2.3-OIONE 5~ 71 99 01561 DECRNRL #1567 100 .` 50 ~6 0 40 PYRIOINE.2-METHYL-5-I50PROPRNOL- 34 132 136 \ ~i I 60 60 100 120 140 MassiCharge__ . T: null. Z: Scan 2155 (34.575 min) of GRRPHICSCD Y: TiC of DRTA:RCHER03A.D [MS2I X: Set of 4 MS Scan 2206 (35.226 Nin) of OATA:ACHEA03A.D MENTHOL EXTRACT m/z abund. m/z abund. m/z abund. m/z abund. 28.15 100 32.15 53 43.25 41 71.15 35 29.15 42 41.25 34
Page 328: nbi31d00
LIBRARY SEARCH RESULTS Scan 2836 (43.249 min) of OATA:ACHEA03A.D MENTHOL EXTRACT Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library. Match Index 4 Quality I: NICOTINE 0 7 9949 2: NICOTINE 0 236 9949 3: NICOTINE,ISOMER (SL 190) 0 874 8939 4: PYRROLIDINE,2-ETHYL-1-METHYL- 1 1156 8738 5: PYRROLIDINE,I-PROPYL- 1 1155 8510 6: ANABASINE 0 498 8431 7: PIPERIDINE,2-ETHYL- 0 1137 8147 8: PYRROLIDINE,I-ETHYL- 1 1150 8105 9: GLUTARIMIDE,3-METHOXY- 0 767 8101 10: PYRROLIDINE,2,5-DIMETHYL- I 1151 7974 100I ¢ Bcan 2836 (43.249 mtn) of ORTR:RCHER03R.1] 4? 65 \ 119 133 162 .i... .~ ....64 l I N AL a 4 / 2 1 4 / 2 I #7 NICOTINE I119, 1.33 161 134 ( I, u 1m0 rla0 \ 236 NIC 1/ 9 OT ~ 3 1INE 61 C1~~ I B4 ii 1. 1 L.,1 #674 NICOTINE.\ ONER (SL 150) 180 55 175 204 ~10A S13~ 42 ,/ ~64 \ 0 I © 5'~ -~---r 40 60 60 1013 120 140 160 180 200 MarriCharge To null. Z: Scan 2206 (35.226 min) of GRRPH]CSCD Y: TIC of DATA:RCHER03R.D [MS27 X: Set of 4 MS Scan 2836 (43.249 min) of OATA:ACHEA03A.D MENTHOL EXTRACT m/z abund. m/z abund. m/z abund. m/ z abund. 28.15 12 5 0.15 4 77.15 4 117, 15 4 29.15 3 5 1.15 10 78.15 6 118. 25 6 30.15 3 5 2.15 3 79.15 3 119. 15 10 32.05 3 5 3.15 3 82.15 7 120. 15 3 38.15 3 5 4.25 3 84.15 100 130. 15 4 39.15 11 5 5.05 6 85.15 6 133. 15 33 41.25 7 6 3.05 6 91.05 4 134. 15 4 42.15 33 6 4.05 3 92.15 7 161. 15 17 43.15 3 6 5.15 7 104.15 3 162. 15 18 44.15 3
Page 329: nbi31d00
50,' S 5 ?5.95 1 134.35 3 1E2. 10 17 51.1 5 13 77.35 4 105.05 2 163. 10 2 52.0 5 4 78.05 ? 136.05 1 LIBRARY SEARCH RESULTS Scan ~90 5 (44.'Z3 * in) of DP,TA:ACHEA0 IA.D LIGHTS E Library XTRACT filc: DAT A: TOBACCO.L Library na-c: TOB AC CD AND SMOKE COMPO NENT S CAS k Libra Indcx ry it Match Quality ': NICCTINE 2' "JICDTINE ~' "JICCTIME,TSCMEP, (SL 19D) p,: PYRROLIDINE,2-ETHYL-I-METHYL- 5: PYP,ROLIDINE,1-PRCPYL- 6: ANAOGCINE ?: PIPEPIDINE,2 Er,HYL_ 8: GLUTARIMIDE,3-11ETHOXY- B; PYP,ROLIDINE,1-ETHYL- 13; PYRRCL.IDINE,2,5-DIMETHYL- F ieo m1n) of 3 7 9"3 0 236 99?3 0 874 8990 1 1156 8744 I 1155 8543 0 498 8435 0 113? 8210 0 767 8164 1 1153 813? 1 1151 8334 ORTR:RCHER01R.0 1 13 - 133 1 8 P N? NICOTINE ~~ ity 161 n I~ 0236 NICOTINE 3 11301 1 139 181 160 ~ n J I ii ~ ik6ir l iJICuTINE,ISGMEk . u 1 4 2 55 50 I i i` f 21 'L j-. ~E GE tltl 130 12© 144; Ma;:: Charlyc i5l. 150) 17S 204 i0~ ~ ~ 50 Pi 1CW 1tla ~DO 1: null. Z: Scan 2899 (44.044 min) cf GnAFn1CSCD Y: TIC of DATA:ACHEMIA.D L19SL1 x: Sa1 of 4 MS Scan 2905 (44.123 Min) of DATA:ACHEA01A,0 LI6HTS EY,TP,ACT r;z abund. N/:z abund. rJz abund. n1 z abund. 28.0 5 12 52.05 5 78.35 5 137, 15 1 29.1 5 2 . ,35 C7 ~ 19.35 2 117. 23 5 33.3 5 3 54.35 3 80.35 2 118. 13 5 32.0 5 2 55.05 6 81.15 2 119. 10 9 37.0 5 1 56.05 1 82.35 7 120. 20 2 38.1 5 3 57,15 1 84.05 100 130. 10 6 39.) 5 lt 62.05 1 85.35 E 131. 20 2 40.3 5 2 63.05 5 90.05 1 l33. 23 33 41.1 5 0 64.05 3 91.35 3 l34. 1fl 4 4V.1 5 31~. 65.35 1 92.05 7 159. 10 2 43.I r 3 66.05 2 M .9i5 2 1F1. !P. IR Scan 2905 (44.123 4f 65 IR4
Page 330: nbi31d00
LIBRARY SEARCH RESULTS Scan 2080 (33.604 min) of DATA:ACHEA03A.D MENTHOL EXTRACT Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: MENTHOL 0 132 8197 2: CAMPHOR-D 0 1547 7224 3: PHYTOL 0 5S 7201 4: CYCLOHEXANE-1,2-DIOL,1,3,3-TRIMETHYL- 0 1629 7135 S: LINALOOL 0 1556 7001 6: LINOLEIC ACID, METHYL ESTER 0 1741 6927 7: OCTEN-6-AL,3,7-DIMETHYL- 0 1453 6825 8: IONONE,TETRAHYDRO- 0 1503 6709 9: NEROLIDOL 0 1612 6660 10: MARIOLIDE, DIHYDRO- 0 1745 6641 Bcan e060 C33.664 mtn] of ORTR:RCHER03R.0 100 1 13B r100 ' y 1 109 123 I~ID~ 43 I /k13z MENTHOL 15 ~ l aII 9 I1 123 138 ° 01547 CRMPHOR-0 3 1©!8j ~ -,_,,. / r100 ¢ 0J Il1 l5 ~~BI I 95J I (p 7I~a6 10© , 50 43 L © 4e 055 PHYTOL 95 123 / 60 90 100 120 140 _ Maza/CharBe T: null. Z: TIC of DATA:ACHEA02A.D GRRPHICSCD Y: TIC of DATR:RCHERD3A.D [MS21 X: Set of 4 MS Scan 2080 (33.604 min) of DATA:ACHEA03A.D MENTHO[. EXTRACT m/z abu nd. m/z abund. m/z abund. m/ z abund. 28.15 21 45.15 5 70.15 18 85. 15 7 29.15 51 51.15 5 71.05 90 93. 16 5 31.15 11 53.15 15 72.15 6 95. 15 62 32.15 8 55.15 63 77.05 6 96. 15 19 39.15 38 56.15 26 79.15 6 109. 25 12 41.15 100 57.05 40 80.16 is 110. 15 6 42.25 16 67.15 42 81.15 77 123. 25 28 43.15 55 66.15 14 82.16 30 138. 25 14 44.15 12 69.15 37 83.15 13
Page 331: nbi31d00
LIBRARY SEARCH RESULTS Scan 2838 (43.275 min) of DRTA:ACHER03A.D MENTHOL EXTRACT Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS 4 Library Match Index A Quality 1: NICOTINE 2: NICOTINE 3: NICOTINE,ISOMER (SL 19D) 4: PYRROLIDINE,2-ETHYL-I-METHYL- 5: PYRROLIDINE,1-PROPYL- 6: ANABASINE 7: PIPERIDINE,2-ETHYL- 8: PYRROLIDINE,I-ETHYL- 9: GLUTARIMIDE,3-METHDXY- 10: PYRROLIDINE,2,5-DIMETHYL- Scan 2636 [43 75 I0G7 ...1.., 42 65 .~.1.. .~... 4 / 2 \ V, ( 64 eiln) Df ORTR:RCHER03R.0 1j19 ~93 L 1 / 62 n /P7 NICOTINE N 1i9 ~3 ~ .~ k296 NICOTINE I\ 119 ~133 i , 84 ~ k674 NICQTINE,ISaMER !d0 \ 42 55 50 / / 84 40 60 60 100 120 140 Mass/Charps GRAPH]CSCD [MS27 161 J 11 7 9972 236 9972 874 9015 1156 8733 1155 8598 498 8420 1137 8200 1150 8190 767 8153 1151 8058 (5L 190) 17_9 2q5, 00 \\ 0 160 160 200 T; null. Z: Scan 2836 (43.249 min) of Y: TIC of DATA:ACHER03A.D X: Set of 4 MS Scan 2838 (43.275 min) of DATA:ACHEA03A.0 MENTHOL EXTRAC m/z a T bund, m/z abund. m/z abund. m/ z abund. 28.15 13 44.16 4 77.15 6 106. 15 2 29.25 3 50.15 4 78.05 6 117. 15 4 30.15 3 51.15 11 80.15 3 118. 25 7 32.15 4 52.15 5 82.15 7 119. 15 9 38.15 4 53.15 3 84.15 100 130. 25 5 39.15 10 55.05 5 85.15 7 133. 16 31 40.15 3 62.95 5 91.15 4 134. 15 5 41.25 8 64.15 3 92.05 8 161. 15 16 42.15 34 65.05 7 104.15 2 162. 15 16 43.25 4 66.15 2
Page 332: nbi31d00
LIBRARY SEARCH RESULTS Scan 2855 (43.476 min) of DATA:ACHEA0IA.D LIGHTS EXTRACT Library fi1a: DATA:T08ACCO.L Library num... TO6ACC0 AMD SMOKE COMPONENTS 1: ^:.COTINE CAS S 0 Librarr Indcx # 7 Matoh Ouali:y o05e 2: MICOTINE 0 236 9950 3: MICOTINE,ISOMER !SL 190) 0 874 oolo 4: PYRROLIDIME,2-ETHYL-I-METHYL- I 1156 8684 5: PYP,ROLIDINE,1-PP,OPYL- 1 1155 0404 6: AP46ASIME 0 "o0 3436 7: PIPEP.IDI":E ,'-ETHYL- 0 113? 8154 °: GLUTARIMIDE,3-METHOXY- 0 767 8107 9: PY.°,P,OLIDIP:E,1-ETHYL- I 1150 S081 1.D: PYRROLIDI":E,°,5-DIMETHYL- 1 1151 7948 Scan 2855 (43.476 mtn) of ORTR:RCHER©1R.0 i6n1.' 42 Cr ~~ .n 133 1R1 ( Ii '160 w7 NICOTINE 3{dp ~ ;120 4e 119 f3 161 lm i i I 4 i ki'96 NICOTINE 1m0~ \ r100 4 P ~ 1Itl f 3 foi I LL / J I on ~ u I I ~ ~ ' Lo k674 NICuTINE ISGtIER (5L 120) . 1©0 4 175 E04 1 i / 84 ~ 50 ~' ~ `. ~ ~ 4d e *-. L - r ~ ^~ T r 45 40 C0 06 160 121; 340 3C© 100 200 ~ _ Hn;S.'CharOe _ GnRFH)CSCD LMSZ1 T: nuli. Z: 5can ?85: (4?.439 min) of i: TIC uf DRTR:RCHERDIR.D X: Set of 4 MS Soan 2855 (43.476 *in) of DATA:ACHEAOIA.D LIGHTS EXTRACT r;z abund. r/z abund. m/: obund. m/ z abund. 20.15 15 44.05 4 77.05 6 117. 20 4 29.15 3 50.15 4 78.05 8 118. 20 5 29.?5 3 51. 1 5 10 79.05 4 119. 10 10 3L.V.CJ 4 ( ~ 5Y.V5 6 8.~. . 05 7 130, 10 6 3°.15 4 54.05 3 54.05 100 133. 10 33 39.05 1? 55.05 4 85.15 5 134. 10 4 41.15 10 63.05 5 91.05 4 161. 10 19 42.15 32 64.05 4 92.05 8 162. 10 16 43.15 3 65.05 9 104.05 3
Page 333: nbi31d00
LIBRARY SEARCH RESULTS Scan 2890 (43.946 min) of DATA:ACHEA03A.D MENTHOL EXTRACT Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: 2: 3: 4: 5: 6: 7: 8: 9c 10: NICOTINE NICOTINE NICOTINE,ISOMER (SL 19D) PYRROLIDINE,2-ETHYL-1-METHYL- PYRROLIDINE,I-PROPYL- ANABASINE PIPERIDINE,2-ETHYL- PYRROLIDINE,1-ETHYL- GLUTARIMIDE,3-METHOXY- PYRROLIDINE,2,5-DIMETHYL- 7 9927 236 9927 874 8940 1156 8678 1155 8511 498 8411 1137 8148 1150 8106 767 8102 1151 7975 Scan 2890 (43.946 mtn) of ORTR:RCHER03A.0 100 42 65 119 183 100 162 ~ .. .. , .e.~[ .i~.~... .. ~. ...~.... ~ g 4. .~... .n . [ . / l._ 42 / 42 1 ~' 67 NICOTINE /~ 1 1 9 y a 161 I B4 ~ ~II 0238 NICOTINE B4 1% 9 129 I 8874 NICOTINE.ISOMER 42 / il[ f 40 60 Bm GRRPHICSCO [MS27 B4 100~ 120 140 Mass/Char~e 161 n [BL 190) 175 Q04 100 ~ ~90 ~ i r~d 180 1813 200 T: null. Z: Scan 2851 (43.443 min) of Y: TIC of DRTA:RCHERD3A.D X: Set of 4 MS Scan 2890 (43.946 min) of DATA:ACHEA03A.D MENTHOL EXTRACT m/z abund. m/z abund. m/z abund. m/ z abund. 28.15 10 53.15 2 78.05 7 106. 15 2 29.15 2 54.15 3 79.05 2 107. 15 1 30.15 3 55.15 5 80.15 1 117. 15 4 32.15 1 56.15 2 81.15 2 118. 15 6 37.05 1 57.05 I 82.15 6 119. 15 10 38.15 3 62.15 2 84.15 100 120. 15 2 39.15 11 63.05 6 85.15 6 130. 15 5 40.15 2 64.15 3 89.05 1 131. 25 1 41.25 8 65.05 8 90.15 1 133. 15 33 42.15 33 66.05 2 91.15 4 134. 25 4 43.25 2 67.05 2 92.75 R 1 S4_ 15 1
Page 334: nbi31d00
LIBRARY SEARCH RESULTS Scan 2851 (43.443 min) of OATA:ACHEA03A.0 MENTHOL EXTRACT Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: NICOTINE 0 7 9878 2: NICOTINE 0 236 9878 3: NICOTINE,ISOMER (SL 190) 0 874 9031 4: PYRROLIDINE,2-ETHYL-I-METHYL- 1 1156 8819 5: PYRROLIDINE,t-PROPYL- 1 1155 8573 6: ANABASINE 0 498 8463 7: PIPERIDINE,2-ETHYL- 0 1137 8223 8: GLUTARIMIDE,3-METHOXY- 0 767 8176 9: PYRROLIDINE,I-ETHYL- I 1150 8175 10: PYRROLIDINE,2,5-DIMETHYL- I 1151 8057 a u 3 IOId, Jo i ra 1 GI 0 50 0 Scan 2851 (43.443 mtn) of ORTR:RCHER03R 42 78 ~ 119 133 161 !el i...~~ .64 .e .1. U i 1 / 1 k7 NICOTINE \ IB4 1i9 .133 161 .i L II 0 1©B _ 0236 NICOTINE !\\ 119 13 3 161 ~100 84 Ii 1 1. I L•a #B74 NICOTINE.ISOMER (SL 190) ' ~/~ - "- / ti - 40 613 B0 GRAPHlCSCO [MS2I I 175 2D4 100 I64 \ p 4 r -r - r~n 100 120 140 160 180 200 Macs/charpe T: null. Z: Scan 2838 (43.275 min) of Y: TIC of DRTA:ACHEAD3A.D X: Set of 4 MS Scan 2851 (43.443 min) of DATA:ACHEA03A.D MENTHOL EXTRACT m/z ab und. m/z abund. m/z abund. m/ z abund. 28.15 17 50.15 5 77.15 4 118. 15 7 32.15 7 51.15 10 78.05 7 119. 15 10 38.35 3 52.05 4 82.15 7 130. 05 4 39.15 14 54.05 4 84.15 100 133. 15 32 40.25 5 55.05 6 85.15 6 134. 15 4 41.25 8 63.15 5 92.15 7 161. 15 18 42.15 29 65.15 7 117.25 4 162. 15 13 44.25 5
Page 335: nbi31d00
51308 7206 N L] U CJ L7 ULJL') O - N M LJ q G] Q L] L] L] L) L7 M v LJ L] r- 0 © 61 LII `W U L7 0 L7 L7 L~ © - - Ci ~f UC] D- O r- r- r- r- r- CJ L7 ^ ~f C.1 C1 L7 L7 Ll L7 .f L9 - CV M ~f L7 Ll U L7
Page 336: nbi31d00
LIBRARY SEARCH RESULTS Scan S999 (83.582 min) of DATA:ACHEA03A.D MENTHOL EXTRACT Library file: OATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: 2: 3: 4: 5: 7: 8: 9: 10: PYRROLE-2-CARBOXAMIDE DECANAL AZETIDINE ACRYLIC ACID,3-(2-FURYL)-2-Me-,Et ESTER PYRIDINE,2-METHYL-S-ISOPROPANOL- OCTANE-2,3-OIONE CYCLOHEXANE-1,4-DIONE CYCLOPENTANONE,2,5-DIMETHYL- HEXANOIC ACID,4-METHYL-S-OXO- PROPANEDIOL-1,3 100, J0 Scan 5995 CB3.56P min7 of ORTR:RCHER03R.0 17•,~ 96 ~ .I I~ IE6 ~ I M1567 PYRRQLE-2-CRRBOXRMIOE 110 N, 66 94 ~2Bi i d II 1 1k1561 DECRNRL N 57 82 / I ~616 il 1567 7264 1561 7111 1128 6652 1533 6615 1587 6416 1558 6247 1566 6126 1509 5925 1529 5795 1627 5555 100 ` fl 01128 RZETIDINE 1003 III~ 26 ~ 57 tF100 50~ i ~'S0 0 u r €--~ 0 20 40 60 60 1B0 120 140 160 Mass/CharBe GRAPHICSCO [MS21 T: null. Z: Scan 2962 (44.881 min) of Y: TIC of DATR:RCHER03A.D X: Set of 4 MS Scan 5999 (83.582 min) of DATA:ACHEA03A.17 MENTHOL EXTRACT m/z abund. m/z abund. 28.15 100 32.05 34 29.15 35 44.15 26 m/z abund. m/z abund. 98.15 64 176.15 26 ul r+ w m ro 'i ~ w 00
Page 337: nbi31d00
Sl v~l 'Z9l L 9P"R ^ qR'C q A7_ si:' Ll 0Z 'lSi i S0'l6 S S6'Z 9 fi Sl'lv E 0t'. 'Y£i S S0'S^o S S0'9 7 i Sl'0`v trE OZ •xrl 00t S0'78 r Si"v 9 ii Si'6P ~ ~ OZ '0Pl S 90'i.8 tr So•z 5 x sl a2 h vf l 0l •fill E SO•ls Zl 50'l 5 £ 50'Zz^ 00 9 OZ '^oli 9 56'LL 9 Si'0 S Z Sl'0i ~ tr 0l 'Lll tr SO'LL b Sl'tr $ ~ Si'6Z a N Y S0 'SOt 3 50'S9 Z CJI'K tr LI Sl'O(. •punqc , ;a •punqc z/W •pu.n.qe Z/w 'pur.qr z;•:: !Q5T '1S? SW h !Q loS :1f f7.SW1 ~'4lSCfi3k~B filklQ f^ ll :' mcirujuvn J./JIiVVVJ fv" 1LiSW Lb'b61 CLbG' 111103 .Z 'llnu :1 aea eaT aaT es aaT Jt Tar 1,ibd1X3 S1H9il 0'dl0N3HOV!HIHO 40 (uFw ^oF9'itr) L£oZ ~-"S .acyD: a-cH CbTV alT 3tlT 013 3a "'b bel / ; Eo~ ~I ss 7 [-eaT ~J31dG5I' 3NI1G7Ini }.l 94 ~ I Fa r t•a i e5t ~'it •~ ~b LaOT 3NI10JIN 95Z# / bBt ~ F.FI fiTT ~\ ~b I aai 3NiiGJIiJ lA r . SST aST ~.I a •\1 81 db Lgq_t 855'bb] GS6Z uQU5 TI ~ at 0'dTDtl3HJd;d1H0 da Cutw S9T 1AH13WiC-S'Z'3NIOI"OaiAd 0 1 -lAHl3-l'3Ni"ui iOiidAd :6 -AXOHi3W 4 30iWladiii~9 :8 -1AH13-Z' 3tJI^ula3did L -1Ad02id-l'3NI0Il0aand :9 3NISv"aviJv : S -1AH13W-i--1AHl3-Z' 3iJICIi"uaand : `v (Col iS) d3W0SI'3Ni10GIiJ :r 3NI100IN :Z 3iJI100 iN :i S1N3idOdW00 3>IOWS aNb 033b801 :ewcu AJ.Jq?l FJCJ^y!~ 1'OJJdal71%dlVU :OITJ 10da1X3 S1H911 ^u'dI0b3HONIN1Ntl 10 (UTW ^or9'trt) LEoZ u= 5 Sli(1S3d HOdkf3S AbH2!^ail
Page 338: nbi31d00
Datc filc: DATA:ACHEA02A.D Filc typc: GC : M9 DATA FILE DJ:,7o Info: REGULAR EXTRACT Mi.... Info: Cpcrotar : JNS Dctc . 12 Aup 86 4:32 pm Inztr*cnt: M9_5970 Inlct SC 6cqucncc indcx . 1 Alo battlc nur . 2 Rcpllcatc num . 1 TIC of ORTR:RCHER02R.0 G"nnFH;CSCD lMSZJ TIC of DATA:ACHEA02A.D REBLILAR EXTRACT 0 Poaklt Rct Ti*c Tyao Width Arco Start Time End Time 1 33.549 PV 0.063 560628 33.506 33.612 2 34.425 PV 0.157 5209339 34.286 34.631 3 43.245 PV 0.193 148728704 43.057 43.616 4 43.876 VU 0.328 496419853 43.616 44.505 5 44.515 VV 0.026 4669412 44.505 44.532 6 44.540 VV 0.190 30538177 44.532 44.860 7 44.879 UU 0.048 2293040 44.860 44.969 8 81.633 PV 0.019 112330 81.608 81.648 9 83.404 VU 0.035 607330 83.377 83.429 10 83.467 VV 0.123 2522629 83.429 83.608 11 GJ.G4G VV /~ V.©J2 10070OG 03.G00 83.685 i2 0 3.740 VV 0.000 10G100G 03.7LJ 03.017 13 (~ U4.JJV J'J ©.©IJ 110202 04.370 04.412 14 OG.104 ^V 0.034 270202 00.150 OG.250 Ir I U0.4JL IJ 0.047 424350 1D.J7/ OO.4aL T: TIC of DRTA:RCHERDIR,D Z: TIC of DRTR:RCHERDIR,D Y: TIC uf DATR:RCHERDIR.D X: I 1 l: of UH I H: HI;HEHUCH. U
Page 339: nbi31d00
LIDR,IRY SC1rCI I rcSuLTS Scan 2145 t34,42C viin) of DrIT(1:CCIICT©2lS.0 RCCULI^ C)(TRACT Library fi1e: D1TA:TODfiCCO.L Library naraa: TDO(1CC0 AND SMOIIC COMf'OMCrJTS C IJ 1: DCC^N1L 0 <^: MCrJTIICL 0 3: CYCLOIIG(1rJC 1,2 DIOL,7,J J TRIMCTIIYL © 4: LIPJRLOOL 0 r: p 5UC IIr, DInrJIYDr,IDC cSR 11eD) 0 G: UNDECANAL 0 7: GUCrr DI ;rJllYD^IDC ;Cr 44D) © u: i'li`iTCL © 0: rJCI]DLICDL J 10: rCrdrnDCCIrJnL © 12 2 Scan 2145 (34.429 min) of ORTR:RCHER62R.0 1~~~I ~lII ~~ ~i~`7 ~1 ~s ('w1d 1ce i I 2B m 4.~^I k15c1 oCCrNnL 82 0132 MENTHOL ~ 1 = i 11 1 1 B~ -^-- 80 IOP+ 11asx: Char ea ffiItlYtl CY'LLUHtXHNL-1,[-UlUL,1,8,8-IKIMLIHYL- / ~ 55 1 43 I • •--_-• r .-r., _ , 40 SO GRnPH1CSC6 [MS2] ~J-~- 111 12r' l_ I 120 Library Match Index t Quality 1SG1 G913 132 GG30 1020 0405 1JGG G47© DG2 G4J4 1^G4 G444 DGO G441 JJ G2JG 1GIC G243 1454 C242 r 1: null. / [ \ Z: SCSfl 2076 U SVJ..SIJV :i111:J of Y: TIC of GRTn:RCHEF02R.G X: Set of 4 MS I 'can 2145 (34.42`J r•lin) of Dr~TA:ACIICA32A.D r,"EGULrl^ [xrr,rCT mi /z sbund. r•1/z abund. M/z abund. ra/z abund. 20.15 100 JJ.1J 42 JJ.1J •IJ 11,1J 20.15 G4 41.15 00 G7.0J 50 01.©J 'l^1 /~r' r'/~. (~ r !' JL.WJ J1fI 4'~J,1r' J IL IIJ.IJ 4G JJ,1J +
Page 340: nbi31d00
LIBRARY SEARCH RESULTS Scan 6370 (88.309 min) of DATA:ACHEA03A.D MENTHOL EXTRACT Library fiie: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS # Library Match Index # Quality 1: OXAZOLIDINE-2,4-OIONE,S-METHYL- 0 1725 7890 2: OCTANE-2,3-DIONE 0 1558 7697 3: DECANAL 0 1561 7320 4: PROPANEDIOL-1,3 0 162? 7113 5: PYRIDINE,2-METHYL-5-ISOPROPANOL- 0 1587 7094 6: HEXANOIC ACID,4-METHYL-S-OXO- 0 1529 6999 7: PYRROLE-2-CAR80XAMIDE 0 1567 6867 8: BUTAN-1,3-DIOL 0 1752 6690 9: ACETAMIDE,N,N-DIMETHYL- 0 1559 6376 10: AZETIDINE 0 1128 6209 Scan 6370 (BB.309 m1n) of DRTReRCHER03R.0 I00 .~ r100 0~1 1~2B IPI ~fl5 k1725 OXRZOLIOINE-2,4-DIONE,5-METHYL- 100 13 u 0] 26 I I~73 7/ 115 I c e ~ 81556 OCTRNE-2,8-DIONE 3 ltam-1~` - 55 71 99 I r100 Q 28 43 ~ / / n J IIL.00 Ik1561 DECRNRL 00 IBW `. 41 [so 5D 28 ~ ~ e .12 30 40 56 813 70 Bfd 913 I00 110 __ MassiCharpe T: null. Z: Scan 6238 (86.628 min) of GRRPHICSCD Y: TIC of DRTR:RCHER03R.D [MS2] X: Set of 4 MS Scan 6370 (88.309 min) of DATA:ACHEA03A.D MENTHOL EXTRACT m/z abund. m/z abund. m/z abund. m/z abund. 28.15 100 31.05 38 43.15 41 45.15 53 29.05 42 32.15 57 44.05 31
Page 341: nbi31d00
Data file: DATA:ACHEA04R.D File type: GC / MS DATA FILE Name Info: LIGHTS 30 Misc Info: Operator : JNS Date : 12 Aug 86 8:15 pm Instrment: MS_5970 Inlet : GC Sequence index : 1 A1s bottle num : 4 Replicate num . t
Page 342: nbi31d00
LIBRARY SEARCH RESULTS Scan 2962 (44.881 min) of DATA:ACHEA03A.D MENTHOL EXTRACT Library file: DATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS I: NICOTINE 2: NICOTINE 3: NICOTINE,ISOMER (SL 19D) 4: PYRROLIDINE,2-ETHYL-1-METHYL- 5: PYRROLIOINE,I-PROPYL- 6: ANABASINE 7: PIPERIDINE,2-ETHYL- 8: GLUTARIMIDE,3-METHOXY- 9: PYRROLIDINE,1-ETHYL- 10: PYRROLIDINE,2,5-DIMETHYL- CA5 # Library Match Index # Quality 0 7 9815 0 236 9815 0 874 8849 1 1156 8643 1 1155 8379 0 498 8361 0 1137 8115 0 767 8069 I 1150 7981 I 1151 7848 Sc:n 2962 C44.881 mtn7 of DRTR:RCHER0BR.0 160, 42 }I ~ 65 ~ 4 / 2 4 / 2 I\ 133 1fi1 6 1 r j 64 07 NICOTINE \ 119 f 3 161 84 1 Ik296 NICOTINE \ 11g ~ g 1e1 r100 19 *874 NICOTINE.I5011ER C5L 1607 1003 55 N 175 20`4 ~t'1®0 5©~ 42 / I B4 ~ \ ~30 """~~~IC 40 60 60 100 12m 140 1613 16A 200 Narc/Charge GRAPHICSCO [MS2] T: null. Z: Scan 2956 (44.8D4 min) of Y: TIC of DATA:RCHERD3R.D X: Set of 4 MS Scan 2962 (44.881 min) of DATA:ACHEA03A.D MENTHOL EXTRACT m/z ab und. m/z abund. m/z abund. m/ z abund. 28.15 21 44.05 6 77.15 5 118. 15 7 32.15 5 50.15 7 78.05 7 119. 25 9 ~ ~ 39.15 14 51.15 9 82.15 7 130. 15 5 w 41.15 10 52.15 5 84.15 100 133. 15 34 m co 42.15 30 55.05 8 85 I5 6 161 15 16 43.25 5 65.15 9 92.15 8 162. 15 13 V f-. .`Oi
Page 343: nbi31d00
Data file: DATA:ACHEA05A.D File type: GC / MS DATA FILE Name Info: REGULAR 30 Misc Info: Operator : JNS Date : 12 Aug 86 10:06 pm Instrment: MS_5870 Inlet : GC Sequence index : 1 R1s bottle num : 5 Replicate num t
Page 344: nbi31d00
44,25 3 68.15 1 93.15 50.15 5 75.15 1 103.15 51.15 11 76.15 1 104.15 52.15 5 77.15 4 105.15 LIBRARY SEARCH RESULTS Scan 2951 (44.739 min) of DATA:ACHEA03A.D MENTHOL EXTRACT Library file: OATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS CAS tk 1: NICOTINE 0 2: NICOTINE 0 3: NICOTINE,ISOMER (SL 19D) 0 4: PYRROLIDINE,1-fROPYL- 1 5: PYRROLIDINE,2-ETHYL-1-METHYL- 1 6: ANABASINE 0 7: PYRROLIDINE,1-ETHYL- I 8: PYRROLIDINE,2,5-DIMETHYL- 1 9: PIPERIDINE,2-ETHYL- 0 10: GLUTARIMIDE,3-METHOXY- 0 2 161.15 16 1 162.15 16 3 163.15 2 2 Library Match Indax # Quality 7 9823 236 9823 874 8910 1155 8602 1156 8509 498 8222 1150 8193 1151 8070 1137 7990 767 7944 Snan 2951 (44.739 mtn) of ORTR:RCHER03R.0 100 ~ r3 42 65 119 ,133 1 6 I/`01 00 0 . . .i.,~ . i. ~ B 4 ~ 1 n c 3 42 42 I #7 NICOTINE \ 1 l9 152 161 ('100 I64 / II ~I \ 236 NICOTINE I 64 1 tl / 9, ~ 3 1. 0874 NICOTINE.ISOMER 100 1 42 55 50 / / 0 --+-r~-----r 40 60 60 ORRPHICSCO [MS'2] 94 100 120 140 Mass/Charpe 1~ 1 ~ (SL 190) 175 204 1100 S0 160 180 200 T: null. Z: Scan 2890 (43.946 min) of Y: TIC of DATA:ACHER03A.D X: Set of 4 MS Scan 2951 (44.739 min) of DATA:ACHEA03A.0 MENTHOL EX m/z TRACT abund. m/z abund. m/z abund. m/ z abund. 28.15 16 44.15 4 77.15 6 117. 15 6 29.15 4 50.15 5 78.05 5 118. 15 7 32.15 5 51.15 13 82.15 6 119. 15 10 38.15 4 52,15 6 84.15 100 130. 15 5 39.15 13 55.05 7 85.15 7 133. 15 31 40.25 4 63.15 6 91.15 4 161. 15 16 41.15 9 65.15 10 92.15 9 162. 15 15 42.15 41
Page 345: nbi31d00
LIDR ~RY ~C11RCII RCCULT~ Jl.an 5047 (0{.GJL (•11n) of DISTII:IIC11CIIOLII.D REGULAR EXTRACT Library file: Df1TA:TODPICCO.L Librery nar•a: TODACCO AND SMDlfC COMI'ONCNTP CAS # Libra Index ry # Match Quality 1: ^YRROLL L ClIRDDXlSMIDL 0 /JG7 70 4J 2: ACRYLIC ACID,3 (2 rURYL) 2 Me Cl 4 CSTCR 0 W 1G33 ~,, 7004 3: DECANAL 0 S CG { G94G 4: r"(RIDINC,2 MCTIIYL r IfOf RO^f1NOL 0 1507 GOOD 5: rROf1NCDI0L 1,3 0 1027 C70G C: MLTIIYL ISMIhJC,hJ MCTIPIL 0 1205 CC4S 7: OCTANE 2,3 DIONC 0 1GG0 G4'J7 0: CYCL01'CNTI1NOF1C,2,D DIMCTIIYL 0 1G00 0342 J: I"CLT ~ IMIDC,hJ,tJ DIMCTIIYL 0 1550 0274 f W. ( ry C`ICL4IIGAIIhJC/~IIhJC 1,'4 DIDIJI. 0 1GGG GL37 ~ Scan 5B47 (B1.632 min) of ORTR:RCHER02R.4 I INIG 1~ r1a10 i aJ ii rB I/pu I ~ I In Ik150' rYFROLC 2 CnRDOXnMIOC 100 1I'\ 66 93 110 ('100 pJt2Bi 1_'ii ~ L~~I '° 01533 ACRYLIC RCI0.3-(2-PURYL)-2-He-,Et ESTER L ' z 100, C 'j 106 1g„5 152 1B_0 O00 ' "+JL{ta iLL 0.1 lu u i I I I IF17tl1 utl:HrvML I 10«I ~ ~100 i 56o 1 26 p L 40 60 60 10a 120 i4i l00 IoFI 11as:: CharB® T: m/{ 1. Z: Soan :963 (11.079 min) of GRRPHiCSCO Y: TIC of D"nTR:RCHER3ZR.6 (MS2l X: Set of 4 MS 'carl '1047 (01.G32 rlin) of DI1TI9:l1CIICfl0211.D RCCULl1R EXTRACT rs/z abund. n/z abund. rnlz abund. rn/z abund. 20.15 100 32.15 40 44.1J 34 4J.1J 4J -l~ nr ar JI.LJ JU
Page 346: nbi31d00
LIDR^RY SC(tRCll RESULTS r 'csrl 2037 (43.242 min) of DP/TA:I1CIIC(102A.D RCGUL^R EXTRACT Librar y fi]a: NTPI:TODI1CCO.L Library nama: TODACCO AND SMDkC CDMrONCNTG 1: NICOTINC 0 2: NICOTINC 0 J• IYICDTINC,IJDMCR (SL lOD) 0 4: rvr,ROLIDIPJC,2 CT1rIL I MCTIn~L 1 G: r`fRRCLIDINC,1 rr,orVL 1 G: n.InDnrIr.l~ 0 IllYll IIJ IY 7: rIrCRICINC,2 CTIIYL 0 0: "YRROLIDINC,1 CTII`lL I ~: GLUT ~RIMIDC,3 MCTIIOX`/ 0 10: rYRRCLIDINC,2,5 DIMCTIIYL 1 M' NICOTINC 4 3ty 133 IB! ~1 u Scan 2B37 (49.242 m1n) of DRTR:RCHERB2R.0 tI~IG~ 4P B7 ~\. il35 I tiq 3e£ r'1IdN p ., . .~.,L, .~..,.,.:... ..~. ,. I. . u 1.~~~1. .~.... B 4. .... 42 1 i I z GRn"rriiCSCD [MS2] \M236 NICOTINE 04 11s 12° lsl r1®0 Illl,,,,,,i N1L'UIlN6,17iVMtK r,i4 'e4 sr, Ba 1E0 1£6 140 rlaxz: ChlarBr l S L 1 y W 17\5 264 ~4 ~ lso 3BD £q0 Library Match Index x quality 7 fC1~DYJGGD LJ JG J 074 D003 11JG 07;0 11JW DJ71 400 0433 1137 0200 1150 D1G4 7G7 0159 11J1 0031 iBo 50 T: nnll. 2: Scan 2115 (M.924 min) of Y: i1C of DATRtRCiiERGZn.G X; Set of 4 MS r Scan Z037 (43.242 m, irl) of Dl1Tf1:1CIICA021^.D RCGU`1R CXTRIICT NJz LV.1J abund. 11 raJz JJ.EJ abund. L n7/z 00.flG abund. 2 ralz 107.15 abund. 1 GJ.1J f^. J4.1J J 01.0G 2 117.10 J JD.LJ J JJ.1J G D2.1G G 110.1G G JL.1J 1 JG.1J 1 04.15 100 11'J.1J a JV.LJ J GJ.flJ J DJ.IJ G 1L©.1J J JJ.1J 11 G4.IJ L DJ .1J 1 1„~Ifl.1J J 40.1J 3 0J.0J 0 ~, W.1J J 1J1.1J i 41 25 D GG I ~Y T . . J i J1.1J M 4 133.1J . iL 42 150 J3 G7 0J Z J L 1G 0 134 1G 4 . 4J 1J . 1 ~Y . . . J GD. J 1 JJ.1J L 1JJ.IJ L 44.IJ J 7C.1J 104.10 3 101.15 1C
Page 347: nbi31d00
rn ~r . '~'~ ~r 4 105.10 JV.~J Y II J Y J1./. 11 70(~.1J u 1©G.1J JL.IJ J 7J.1J 2 LIDRPiR`i SEARCH ^EGULTS 'can 20UG (43.077 rnin) cf DATlt:(1CIIL(102A.D RCGULIR CXT^ACT Library file: D1TA:TOOIICCD.L Library nar•1a: TQOACCO AND SMOKC COMrONCNTS 1: NICOTINE 4: IJII.OT:NL 3: rJICOTINC,IGOMC^ (SL 100) 4: rl'RROLIOINC,2 CTIIYL I MCTI{'lL ~: r`lR"OLICINC,1 rROrVL G: t1NAIC1SINC 7: rlr[^IDIN~,z rrrrL 0: rYRROLIDINC,1 CTn1L 9: GLUTnrIMIDC,3 MCTHOXv 1 nv : r'm,r,oLIDINr ,2 s DIMITI ,'rL F 1,"1 I L 1G2.1J IG < 1GJ.1J L C1~ # Library Match Index # Quality © 7 0023 0 230 0023 0 074 0047, 1 11SC OGC7 1 1155 IIJJJ Q 400 0373 0 1137 0130 1 11J0 0127 © 7G7 C©J1 1 11G1 70'J7 Bean ^cBB6 (43,.877 m1n) of I]RTR:RCHERBYR.I] SE2 4w 63 1'\• 113 tt ..Iw.. .1.~ ~.. ., n ... ......... ..n. ..... .~n. ~ ~ A84 ~ ~.~~ .. .M. I 67 T.ZCaTINC I 10Q, 42 ~~ 119 133 161 B4 ~ ~~ ` I ~ c N a 0238 NICOTINE N ~j • 119 123 I 04 i i[ 11 /Ftl/4 N1l:UI 1NL, 1':.'UN1LK 1EE~ Sg I\. 30 84 40 sE sE SoE 12E 140 Nass/CharBe t!~ u SyuJ 175 204 1EE SsE 1sE 200 T: mill. 2: Scan 2°37 (^2.2q2 mio) of GRnFHiCSCO r: TiC of DFiTR:RCHERG2R.G [MS2] X: Set of 4 MS Gca 200G (43•077 min) of DI1TI1:f1CIIC(1©2(1•0 RCGULIR CXTRICT n/z abund. n/z abund. Lt~ni.1J 10 J4•1J J LJ•1G L JJ•1J G JqYJ.IJ L JG,©J 1 32. 15 1 J7•1J 1 J7.LJ I GL•©J L GJ.YIJ J G4•1„ J GJ.OG 7 00.05 Z 07.1G 2 r5/z abund. r•i/z, abur-pd. 70.1J L 11G•2J 1 00.15 2 117.15 4 O1.1J 2 110.10 G 02.1G 0 110.15 0 04.15 100 120.15 L QJ.1J J IJ©.1J J 0^~J.1J 1 131.IJ L 4 ~tl . 1 J 1 133115 J J 91.1G 4 134.SG 4 72.15 7 144.15 1 1 r1:~ or 71 1 yy!1 :lr
Page 348: nbi31d00
09 f QZ X 09 X 5 SZZL 80£TS ~rrYVl9NY1~ (~{ hr.wn~~+ ~(yyot -)q av ~ o~ oa o
Page 349: nbi31d00
9ZZL 80ETS ol RqIWN -PLI 9 s ~ i ~ i --1-- 0 ^- 0'1 - 0'9
Page 350: nbi31d00
LID^'1RY SC~ RCII ^CSULT~ Scan G00f"i ("v3.G4I'i min) of D^Tn:f1ClICf102l1.D RCGUL An CXTrnOT L'.brar y file: DAT1aTODf1CC0.L Library name: TODACCO AND SM01(C COMPONENTS 1: COTININC 2: N MCTIrIL PJNAC(I~INC (SWW 2D) 3: rI^C^IDINC,1 CTtIYL 4: 1,5 DIMETHYL 2 r1'^ROLIDINOrdC G: rYRRCLIDIrdOhC 2, r. CTIIYL G: r'(^ROLC 2 C9RDOXAMIDC 7: CYCLOrCNT(1NOrr'C,2,.r/ DIMETIIYL 0: rl'RROLIDIN L^ ONC,1,G DIMCTIIYL o: MDr,r,ICDTIME,rJ U,IYL (SL 10: rYr,IDIrJC,s tl cT z rYRROLICIMVL) I I Sc an Cf1S # Library Match Index # Quality 0 12 GGG4 0 237 GL44 0 113G C17G 0 40 G130 0 102s C124 0 1GC7 G019 0 ty07 GOD7 0 1370 J714 JOD) 0 070 5550 0 000 ~ 1o 6005 (83.645 mtn) of ORTR:RCHER02R.0 I'~. Jr 17R iWN i 128111 96 I 1 012 COTININC 42 A( / I Sig 147 176 100 I 98 ~ ^ l`ifl~d k237 N-NETHYL RNRBRBINE (9NN 20) 4: ib i I' 1~ B ~ . i ,0 , I W1136 h'll'tKiIJlNL,1-LIHYI- GRRPHiCSCu 0 42 40 fio 6a 106 11sxx: Chsrde 12D 140 1"aQ L a0 T: niill. Z: Scan 5441 (88AB6 min) of Y: TIC of D"niR:Ri.HERGZR.G (MS2I X: Set of 4 MS Scan G00G (03.G4G Nin) of DATA:ACI{Cft02ft.D "CGUL^^ CXT^~ CT ro/z abund. nilz abund. m1z abund. N/z abund. LUIJ '^. 100 AL.IJ 37 dJ.<^J 3G 17C.1J 41 JL.IG JC 44.1J 31 30.15 00
Page 351: nbi31d00
LIORARY GEnr,Cn RESULTS Scan G013 tD3.740 turl) of DnTn:nCIICnOL^n.D RCC•'L1R U(TRACT Library file: DnTn:TODnCCO.L L:brar y narae: TOBACCO AND SMOKE COMI'ONCNTS CnS 4 1: rYRROLIDINONC 2, P: CTIIYL 0 2: CYCLCrC.TnNOPJC,2,G DIMCTIr7L 0 3: COTININC 0 4: f'VRnNONC L(3II), 4,5 DIIIYDRO 0 ~: OCCA INnL 0 C: rYRRDLIDIN 2 ONC,1,G DIMCTIIYL 0 7: rYRROLIDINONC 2 0 0: rYRROLC < CnrsDCXnMIDC 0 0 : rI^CRIDINC,1 CTIrlL 0~ 10: ": MCTI IYL nN(SDn~INC (JWW LD ) / 0 ~ Scan 6013 (63.74B mtn) pf DRTR:RCHERO£R.0 I lee ` I ~ii'BIIi ~B I I RlUL3 / fK1KVLlU1/VU1VL L, IV I" 0j Bt~l 170 If ~B ~I~ 1 3 u IN IO MSSD9 II 190 ~ ~ I" `1 i 176 1 Library Match Indax ik Quality 102G CG3G 1500 G304 12 GJDG 100G 0200 1GG1 G104 1370 C0G2 1JJC JOJL 1GG7 5047 113C 5014 237 50014 IP1L' L'UIlN1NL i'Fj l18 178 k1~~ 56~ 4'K IB i~ 147 `-- 50 4E 66 6E 1D0 1£p 14p a6E I I1aca/Charpe GIit1Y11 i CSI.O [M527 T: mlll. Z: Scar. 8005 (83.645 ain) of Y: TiC of D"nTA:FCiEnu2n.D X: Set of 4 MS Scan G01P, (03.740 riin) of DnTn:nCIICn02n.D RcGULnr, C)cTr,ncT m/a abund. r1/z abund. nJa aburld. rs/z abund. CT1 IYL CYCLpPENTRNUNE.£.5-OIMETHYL- tQ.1J I©PI JL.1J JJ 4L.LJ JJ JD.1J JL L7.1J JJ 41 .1J 34 45.05 34 17G.1J 47
Page 352: nbi31d00
LIDRARY SCftRCll RCSULTG Ccan GOCO (JG.103 r•lin> of D(1Tf1:ftCUG9©L^A.D RCGULI'1R CXTRf CT Librar y fi1e: D(IT/1:TOOf1CC0.L Library name: T00ACCO Ar.D SMOKC COMrOr6CNTS 1: rr,orl1NCDI0L 1,3 ^I. n n Inl L. V lr1VIL s: ocrrraC 2,3 DIOrJL 4: (SZCTIDIrdC 5: r`IRROLC z CArDDX~MIDC G• IICR`ILlG /~ IIGID,J ( L rURYL) 2 Me Ct CSTCR 7: r;,RIDINC,2 MCTlr(L 5 IGOrROr(1tdOL 0: OXAZOLIDINC 2,4 DIOrdC,G MCTIPlL 0: IICXIINOIC ACID,4 MCTIIYL G OXO 10: C`/CLOIICXPNC 1,4 CIOrdC CAS # Library Match 0 Index IG27 Quality 0437 W 1JGI 0020 0 1JJD 75073 0 1120 71400 0 1GG7 7250 0 1533 7213 0 1U7 7211 0 172G 71G3 0 1523 GJ27 0 1CGC OG07 Bcan 6989 C96.1B3 mfn7 of DRTR:RCHER02R.D 11d47 ~ \ 1?p 45 r31db // p I I «aa Ikl C2' r'Rof'fiNC DSOL 1.7 ICD ~'~ 49 ('1~0 ~ OJ ~il6 .f . l 1 9 "`099 N a 01581 DEC RNRL ~ 100 ~ n,1 5~ ~'100 ~ ~ r / B g 11l flfl 1E6~~. 61]Stl UI:IHNL-G 4S .j-UlUNL 99 100 ~ Se~1c6 / 1 3 fl 7~1 \~, 50 50 40 7E 6m iE 60 90 flsas: CharBt T: mill. 1: Scan 606^ (°U98 min) of GRnFHICSCG Y: TIC of unTA:RCh'ERuc'"ir.D [MS2] X: Set of 4 MS Scarl G'J0'C COG.103 rnin) of Dl1Tll:f1CIIC(1©20.D "CGL'L^R CXTR^C7 rn/z aburld. m /z abund. rn/z abund. rs/z abund. lD.IJ 1©1V J/.IJ 44 4J.2J LG 4J.1J JJ LJ.1J JG
Page 353: nbi31d00
~~~r,~4,47s Data file: DATA:ACHEA06R.D File type: GC / MS DATA FILE Name Info: MENTHOL 30 Misc Info: Operator : JNS Date : 12 Aup 86 11:58 pm Instrment: MS_5970 Inlet : GC Sequence index : 1 Als bottle num : 6 Replicate nuro . 1
Page 354: nbi31d00
LIDRARY 5CI'1RCfl RCWLTS Gcan 2035 ((44.517 min) of D19T(1:7lC11C/^021.D RCGUL AR EXTRACT Library file: D11Tf1:TODACC0.L Library nar•1e: TODACCO AND "MOI(C COMrONCNTG CTP « Library Match Index II Quality 1: NICOTINE 0 7 7070 L: L.COTI~YC © LJG 9070 3: i:iCOTINC,I~OMCR (CL 10D) 0 074 0000 4: rYRROLIDIPJC,2 CTIIYL I MCTIIYL I 115G 0000 r : rYRR^ULiDINC,1 rrOrYL 1 11.riJ `JJJ© G: !IN ~D ~~INC 0 400 0412 7: ^IrCRICINC,2 CTIIYL 0 1137 IIIG7 0: r'/RROLIDINC,I CTIIYL 1 1150 O1ZG 0: GLUT/)RIMIDC,G MCT1I0X1' 0 7C7 0120 il~'V: rIr,r,oLIDI":C,L,J DIMCTIII'L I I1J1 709J Stan 2935 (44.517 mtn) Df ORTR:RCHERB2R.D 1NId`~/I 4f 711 _ \ 119 1 q a St ~ 42 I k7 P~TC07If:C I X \ 116 lss 161 64 / 6 ~ i /k236 NICOTINE I4 11 s ._r'' ;61 11• u fl iFkS /4 Nl L:U I 1Nk.. 15UMF.K 42 55 N i / 1 64 .f 40 6E 10w 12Fi 14Fi 11axs: Chsrda GRRPn1CSCD 6E k5L 1NuJ 175 204~ ~ 160 200 T: null. Z: Scar. 2886 ('13.877 rin) of ti: TiC of DRTR:RCHefiD2R.D lMS27 X: Set of 4 MS ~csn 293~ (44.G17 min) of OA?f1:ACIICR02 .D RCGL'LAR N/ Z CXTRACT abun d. r•S/Z 5tUild. P1/ Z abund. P1/ Z afiUild. LV .I J /L J W.1J U 7II .©J 7 117. 15 4 Il LJ./ J 3 J 11.1J 12 ^ 7J.qWJ 4 110. 25 G JL .W J J J 2.15 J VI.©J L 11J. IJ II ~ l.) Jt J r 4 J Y Ir J . I J T J ('1 r VL.1J G I9©. J Ir J r J ( JJ.I J I© J / / ~ Y'.WJ J IIY.IJ 1©© 133. 15 JJ 40,2 5 4 r J r.Ir JJ v 1 05.15 5 r 1 J T 4. r 1 J r J 41.I J I10 G J.IJ C f1 JI.IJ J 1G1. 1J IJ r TT Ir 5 (~b r 1 ~1 •1 1 r 1 r I YL.1 J JJ G 4.J J JL. J U G. J J 43.1 5 T G J r.©r JJ ^/ 1 104.1r0 7 J T I J. 1 r IJ ^I L 44.1 51 4 7 7.15 r
Page 355: nbi31d00
LID^nr,Y SCnacN ^CCULTS c,:an 5cr?G (OS.acs r,in) of DnTI'r.nC1lCnOZn.D r,cGUL,1~ t=XTrnGT Library fi1e: DnTn:TODnCCO.L Library r~arle: TODACCO AND SMOKE COM'ONCNTS CAS # Library Match Irldex 4i Quality 1: COTININ.C 0 12 G'JJJ 2: ^II'CRIDINC,1 CTIfYL 0 113G C000 3: f Yr,r,DLIDIN 2 ONC, 1,5 DIMCTIIYL 0 1370 GG70 »: N MCTIIYL nNnDnGINC (SWW 20) 0 237 GGDO 5: 1,5 DIMCTIIYL 2 fYR^OLIDINONC 0 40 GGG2 G: ^Y^IDINC,3 (I CT 2('1'^ROLIDINYL) 0 JJO DD3D 1 11,1~~~. """^^' 'DINONC 2, N ETHYL 0 102G G517 f1 0: NORNICOTINC,NCTIIYL ~1 (SL1l,'~0D) 0 070 G20~ J: CYGLOIIIXLNONL L,Y 11YO1\OXY J,J,J TI\IMe 0 1JLY GLL1 10: CYCLOfCNTnNONC,Z,5 DIMCTIIYL 0 1N'J G002 Scan 5988 (83.403 mtn) of DRTReRCHCR02R.0 /I 17R 9p ~~ i 012 COTIt~NC 1yyI 42 / j 13B 147 i7s 1°n I m ~ s6 ~ B.. I al~ u ~ N1136 PIPERIOINE,1-ETHYL- t i 106 i 9/ ~~ ~/ 11° r10D 'b I I R1SlFi YYKKUL1lI1N-L-UNt,l,]-L1IMLIHYL- i 1E0~ 41 56 fI klE~ 98, 113 ~30 L 6~ 1 1 III ~'ll '~ i 0 0 2E 42 60 60 10G1 1£13 14Pi 160 ilaxi: Char6a T: mlll. Z: Scan 53'1? (°1.63: min) of GRn"rH]CSCO Y: T]C of DRTR:fiCHEnOZF.D Ef1S2] X: Set of 4 MS Jl.a/l J1J~UG (O~J.YY/J r~in) of DnTn:ncncn©zn.D 1~L V VL1"111 IXTI\/ /niT ralz abund. raJz abund. os/z abund. M/z abund. 2 5 .1J 02 J,,J.1J 21 Y.L.©J 20 JV.1J 10~0, 32.15 YG Y1.LJ L4 YJ.1D 33 17G.1J LJ
Page 356: nbi31d00
LIDR1RY SCnRCII RCSULTO Jcal 200 (44.070 minl) of DnTn:nCIICn©2n.D RGGULI,R EXTr,ncT Librar'y f:1e: Cnin:TODnCCO.L Library naria: TODACCO nND .7M01(C COMrOtJCNTS C1O # t : tJT.COTI/JC "). LIIrnYT/.IC L• 1 Y V V I 11 Y 3: :JICOTINC,ISCMCR 4: rYRROLIDINC,2 CTI{YL I MCTIIYL r. nunnnr Ir J• I//YILLAIJIr,~ G: rYRROLIDIhC,I rRDrvL 7: rIrCRIDINC,2 CTYL 0: GLUTnRIMIDC,°. MCTIiOXY 0: ^YRROLICIPJC,I CTIIYL 10: rvRROLIDINC,2,5 DIMCTIIYL ~ 5can 2963 (44..699 n1n) of DRTR:RCHER02R.0 4P SS \ 11'J IR9 161 1111. 1..'., ~~ ~. 6°; u 42 1 n2 / I , ip7 NICOTINE ~\ 119 _183 161 .84 ~ II ~ u \Ik236 NICOTINE 1'3 r OA 119 k!S/4 N1lUI1NL,1J'UMLk SoF~ 42 S \ S 50'~ '/ 64 4iu 6F] 66 16 0 5267 i40 Hasc/Charye 16i 11 Library Match Index # Qua1~/l'~1ity .~ JJ f 1~1J 2JG JJ15 074 0001, 115G 0020 400 0J<3 1155 0403 1137 0201 ••/Gn n2v. / 1 uCJY 11J0 DWO© 1151 ^J43 L08 ltiL 1'JUl 100 1~S 204 16E 166 206 T: nnll. z: f:;n 243? min) of GRR"rHiCSCG Y: TIC of CiRTR:RCHERFi2R.u [M52I X: Set of 4 MS Jlvall LJGJ (44.C7'C rnin) of DnTn:nCl!cnm2n.D RCGULnR CXTRnCT z abund. a5/z abund. '<C.1J 1~ G1.~I,J JL.IC/ C JL.Y/J JV.LJ J JJ.®J JJ.IJ IJIt, GJ.©J '11.LJ 1V GJ.15 YL.IJ LG •I/.WJ 4 Y.LJ 4 r1/z abund. m/z aburld. 1N ^u.©J G I1J.1J I1 C 02.05 7 130.05 C 0 34.115 100 133.11; J© 7 OJ.1G C 134.25 4 7 JL.OJ 0 1G1.15 17 C 110.1G 0 102.15 14
Page 357: nbi31d00
Luor,nr,Y ccr,rtCll r,ISULTS ;can 71G7 (JO.4JL van) of D(1T11:l1CNCI102t1.D ^CGULAR CXTRl1CT Library file: D(1TA:TOD(1CCO.L Library naroa: TODACCO AND '4M01(C COM'ONCNTS 1: OXl`IZOLIDINC <',4 DICNC,S METHYL 2: I'YR^OLC 2 Cf1RDOXl1MIDC 3: DCCIIN^IL Y: MLTIIYL /~ IIMINL,N MLTII`IL G: ~IZCTIDINC G: ACRYLIC rICID,~ (z ru^YU z Me [t 7: rYr,IDINC,z MCTIIYL 5 IsCf'ROf'FlNOL 0: ACCT MI"uC,fr',N CIMCTIIYL ~: DCT,1NC 2 , 3 DIONL 10: CYCLOIICY,(1NC 1 ,4 DICP.C I I CAS # Library Match Index # Quality 0 17<G 7477 0 15G7 7473 0 1G01 7300 0 120G GOGO 0 1120 0040 CJTCII~ \ W 1533 GG05 0 1507~1 0555 © 1JJJ 0440 © lc~D G4zs 0 IJGG G1J7 Scan 7167 (9B.452 mtn) of DRTR:RCHER02R.p 11dW'~'~ rINN pJl 128 Il II"`LLW115 017215 OX7ZCLI0INC C,4 0ICNC.5 MCTIIYL pp (300 u • pl~ 28 l1P3 7~, 115 "11'idddl C a ~ 01587 PYRROLE-2-CRR60XRMIOE ~ ~ 1213 ES EE l:p ( Iola ~ 1 D 44 5~ ILLLppp/ L p J I~ I, ~ I II 1 615tl1 IJtLHNHL i lE0 "~ 41 p~ 100 I 30 26 ~~ Ji BE ~30 ~ SE 40 5 E 80 70 80 90 1p0 110 i rlasslCharBa T: nnll. Z: Scan 6989 (96.183 min) of GRR"rH1CSC0 Y: T1C of DfiTR:RCHERGZA.D [MS2] X: Set of 4 MS ~can 7107 t00.4G'< vsin) of D ~TA:fICIICAO'<PI.D ^CGUL1R U(TRfSCT m/z abund. o-i/z abund. r., /z abund. rn/x abund. 100 32.05 44 44.05 42 45.05 J© LVI~.IJ GJ.1J 41
Page 358: nbi31d00
LIDr,rIr,Y CInr,Cll r,[CWLTS I Scan 207G (33.GS0 r,ir.) af DATA:(1CIIG102A.D RCCULnR CXTRACT Library file: DI'1TA:T00^CC0.L Library narie: TODACCO AND SMOKE CDMrDNCNTS Cf 0 # Library Match Irrda:; ~ Quality /: DGTIIIVC L,J CIDNC 0 W 1550 0273 2: DCCrIN11L 0 1 GG 1 D2~© 3: IICY,l1N0IC ACID,4 MCTIIYL 5 CXO 0 1520 7GU0 4: rl'RI"uiir'C,2 MCTIIYL C I5D^ROrflNDL 0 1507 7534 G: rYRROLC 2 Cf1RDOX/^MIDC 0 15G7 720'J G: iZCTIDiNG 0 1120 72,'i2 7: CYCLCIICX ANC 1,4 DIDNC 0 1DOG G7C4 D: C)(~IZOLIDINC 2,4 DIDNC,L METHYL 0 17LJ CC04 0: OCRI'LIC ACID,3 (2 I"URYL) 2 Mo Ct CGTCR 0 15,03 GG72 10: CYCLDfCNT^NONC,Z,G DIMCTIIYL 0 1G0D G401 Scan 2076 [33.550 mtn7 af DRTR:RCHER02R.0 11dN'T44 /'1NN qJ~l IE6 I 015,50 OCThNC .-.:I DIONC :OBh,~ 71 99 r300 ,126 1 43 61561 DECRNRL 18 57 EE I II ~ i I i1 K151y HLXHNUlI: 50 ~ 26 I 43 6 -~----r 4E GRnPHiCSCD [hiS2] T: nn11. Z: TIC of DRTfi:PCHEflD1R.D Y: TIC of DRTA:BCHEAG2Fi.D X: Set of 4 MS J.I/ 2070 --G- (3,',.5CO rain> of D1TA:l1CIIC1102Pr.D '' RCCULAR CXTR'1CT M/z abund. m/x abund. r1Jz abund. rn/z abund. sE HL:1U, 4-r'ILIHYL-]-UXU- 96 7A 1 r ~` r &E 10E Hask: Charp6 2D!1.IJ 100 32.05 40 43.15 7r GJ.iJ 30 LJ.IJ 54
Page 359: nbi31d00
LIBRARY SEARCH RESULTS Jcall 203? (YY.JYL r9ir1) of OATC:/ICfILIIVLLD REGULAR LXTR^CT Library file: D^Tlt:T0D19C00.L Library nar•le: TOBACCO AND SM01(C COMI'ONCNTO CIIJ N 1: rJICOTINC 2: rJICOTIr4C 3: NIGOTIrJC,I~OMCR 4: I"lRRQLiDIrJC,< CTHYL I MCTiIYL ~: I~rJ^IO ~:IrJC G: I'YR^cLiDIrJC,1 I R01"i'L 7: rIfCRIDINC,2 LTIIYL 0: GLUT"RIMIDC,3 MCTUOXI' : f'YRROLIDINC,1 CTIIYL 10: "YRROLIDINC,2,G DIMCTIII'L f ~ ~ ~ II I Scan 2937 C44.542 1WIG~ 4fl 7R i~ ~ fC m1n) 09 ORTR:RCHER02R.fl 11 9 f R , I. SE1 1 II NICCTINC 1/19 / _133 tE1 / ~ 0236 NICOTINE ~O \ 119 132 7 I C 4 ~,..~ ' I I II I I. Ipy /4 Nl l:U I 1Nt_. 15UMLK loo sS_ I\ Sta 4i ~/ ' Ba G ~ i a , I+ -T -,- --T 40 BG, EO 10Fi 122 140 Mazz: Cha~t 161 II Library Match Index # Quality 7 0007 23G ~~D7 074 OU1G 11G0 CG01 400 0471 11~~ 0450 1137 0100 7C7 0114 IIJO COJG 1151 7fJL^3 k 51. lyu~ l06 175 224 ~\ `~@ 180 1E6 ^cE0 T: nllll_ Z: Scan 2935 (11.57W min) of Gkli'rHifSCG Y: TlC of GFrTR:RCiiEAGZn.G [MS?7 X: Sat of 4 MS Scarl 203' (44.G4L^ Nirl) af 011TA:ACIICA02a;.D REGULAR EXTRACT r,/z abund. r•i/z abund. LC.IJ 14 J1J.1J 4 J~,Y/./1J 3 JI./I~J 1L JL.'VJ J JL~.WJ J 3C.LJ 3 J`F.1J L JJ.IJ 12 55.15 G 40. 1 J 4 G3.0J C 41.2J 0 64.1J 4 42.15 .~/I,t GJ.qYlJ ~I YJ.LJ Y ~'~ ir ,~ U/.IJ J YY./J 4 nJz eburld. r•i!z abund. 77.1J G 1©J.1J J 70.0G 7 117.f~ 4 7J.©J r 11D.1G G OC.1J I I10.IG 10 04.1G 100 130.15 G CG.1G G 133.1L 3G 01.0J 4 134.1J J OG.OJ 0 1G1.1J IG 104.2J 2 IG2.1J 1J
Page 360: nbi31d00
LIDRARY SCARCN RCSULTS .^,car, 0004 (04.3'C0 r7in) of Dl1T(1:f1CIIC10Cl).D REGULAR EXTRACT Library fiie: DATA:TODACCO.L Library nar•ie: TOCACCD AND SM01(C COMPONCNTS 05 >t Library Match Index it 4uality 1: I'YRROLL 2 CnRDDX^MIDC 0 1GG7 7407 2: DECANAL 0 15G1 7330j 3: 0)((ZCLIDINC <,4 DIONC,G MCTIIYL 0 1^2G COGG 4: I^ILLTIDIIYL 0 1120 C711 r, : ACRYLIC ACID,3 (2 fURYL) 2 Me Ct CSTCR 0 1533 GGOD G: ^`lRIDINC,2 MCTII`lL G IGOi'ROf'f1NOL 0 1r07 CGSO 7: MCTIIYL AMINE,N MCTNYL 0 12055 OGi 1 0: CCTPINC 2,3 DIONC 0 1550 C404 ~: ^CLT(MIDC,N,P: DIMCTI`IL 0 1GG7 0351 10: C`ICLOIICX(1NC 1,4 D:ONC 0 15GG 0134 5can 6064 (64.396 min) of ORTR:RCHER0PR.0 l~b ~\ 44 414 ~Idd q~l 126 11 "4AtF :eory J! i A 1515C7 r•Y:RDLC .^. 44 / cnr•,ooxnMiac 94 i I .I l 01561 DECRNRL 11 5? r ~ 82 i1/27 UXHLUL1l1iNL-2.4-I11UNL,ti-MLIHYL- iuv7 ~I 2B b3 SIh 70 / ~ 3v7 4 0 Co s0 J2 Bo 11aa/Charye so i~,o fim r1130 i ILLLppp/ 115 1 110 T: nnll. Z: Scan E013 (t?,3.798 min) of CnnPHICSCO Y: T1C of DRTR:nCHEF02R.D [MS2] X: Set of 4 MS Gcen G0C4 (D4.300 r•iin) of DATh:11CIlL(102A.D ^CCUL^R L)ITRACT F,/z abund. N/z abund. r•i/z abund. N/z abund. LD.ZJ In nr LU.JJ 10D 32. 05 44 J7 44 . 2 5 44 00. 0C V1
Page 361: nbi31d00
2-) As N~~~.~, Y9. ~.qkyAW4a,' - '" OW coWdaau 9jtW,w tom 3~ ~~ ~f~ - tr'u~ ~lS N~cobAmw ~~ IJic~ww I C(o,u) 8.88 ~ { 2«~ (3z.~E.7o~ Z G.Sb ± L?~ (tRaY~ 3 6.13 f Q•3& `~ 5,00 5 ~~3 t 1,88_ (yt ~~~ S . 7,00 Q ~.63 ~ l3$ Z ~I ~0 7~5 G.V f p'F36
Page 362: nbi31d00
LIDrftrY SCrl^CII RESULTS Jcall 5001 (C3.YYC r'Itn) of D11TA:11CIICl1©2(t,D ^CGULPI" CXT^I9CT Libl ary file: D ~TA:T0D19CCC.L Libr ary rlarae: TOBACCO AND t3M014C COMf ONCNTS CAS 4 Library Match Irdex II Quality 1: VQTINIP:C q /©~ 1L GGJ3 L: N MCTI/`I L IIYIID/M1IJINC ( JWW LD ) C/ L^.37 GL3L 3: "If'CRIDINC,1 CTIIYL 0 11 u G1G0 ff: 1 G DIMCTIIYL 2 I YRROLIDINONC 0 40 C127 J: f Y^^OLIDINONC 2, N ETHYL 0 1825 C0G3 G: rv^aOLC z CI^aOOXnMIDC p IGC7 C~07 7: CYCLOrCNTrNONC,2,G DIMCTNYL 0 1G@0 C031 C: ^`(^^OLIDiN 2 ONC,1,Ci OIMCTII`iL 0 1370 G7©3 D: NOR4JICOTIPJC,N ETHYL (CL 300) 0 070 JJGi 13: ^YRIDINC,3 (1 CT 2 I'YRROLIDINYL) © 930 rG1d Bcan 5991 (B3.488 vltn) of DRTRcRCHER22R.0 ~ r 17A ~1 Id Id II'8dN 96 IL. B1z CoTINIr:C 42 A' 1 f rI 116 147 176 lCo I 9B I IF237 N-METHYL RNRBRSINE (SWW 2E) iAl1I9 i ~1 1' 7ul i 1 I Kl 1:i6 YLf kK11J1NL, 1-E I HYL- iEE ~ ~' iEE 3hi~ iM1 9B i12 4 Sp m~ I r II e E 2E 5E 6E BE fEE f26 14E 18E haa: CFsrm~ _ T: nllll. ^ Z: Scan 5986 (°3."03 mi ) of GRnFHiCSCu Y: TIC of D"nTA:RCHERG2R.D [P1S2] X: Set of 4 MS Ji,ali 5001 (C3.4GG r~lin) of Of1Tn:nCIICn©2r1.D i1CviJLliR CXTnnOT n1/z abund. n/z abund. rs/z LV.IJ JJ~1 Y/O.JJ LJ YIY.1J 3L.ImUJ JY YL.1J .~IC YJ.1J abund. N/z abund. 35 70. 05 143© :n 32 17G.iG 43 ~ W OD V lV !-1 A7
Page 363: nbi31d00
4, EAroict~ oF f 4s - ~ -brtiptAc~ . 6,3q ll1ol (~.o7,) 3,23_.t0,~3- ~-7 010{4 T-tw - pu'3 _ 6,67- -W~ plnFg Oe -tttk _ , 5,4t ;+. o -14 w~ /kwb<.. vw9 5A wAq~pt""q -tuk~s 3.30 . ,t o,04' rr~~~,. ~18 70~ NuMb" eIA- Ttpf+w~ rPaptr
Page 364: nbi31d00
~ 1~15 NicoEann~- - r~u~ar e~ud~~ Ca.uAsvay.- TPA UgG~T 3 g * 0.5 " " , 0~ N(dw;& - IU¢AX&l CAMZo Ww.~Agj UAW* TW ( N 37%, W~ WAU. 6,(a ±o64 AlrO (5D rA)(sQ# ,I 0 MS ~ `tcokune, - w~wur wo,~ w~ivs ~~ , (bac~ ... o-v, ~bar~ ,a~ eM t2o p*) 3.10 t- z.oot -- (a) ESP uxpglri"rks --- %t" C3 rl#. ~30 ~fs .aaeti,) 40 0VT '5p Iw PO* ESP Caubev.
Page 365: nbi31d00
suam~ „„ '2 6)ew~ YAV~ cAtEL 10 . . - Lw i4 .4 IwkK- 4d- in . g ~~) WA pqw - ' T4T~ 40 X qu,tdR"t p(act~t ', Gu vueve A a,w / T A -puf ?-A& J '~ 4 ~~ 1 okaQ nlS oticfx "wsi~" ~s --(c,a.w~e~.~~ _~0 a~a~ _ ~ ~ ~ 0 ~ v ~ 4 ~al ,P ,,. J~) Qua~Od~~.- G('~UUS oF ~ i`.e. . v pu 0.5M G,iMat)
Page 366: nbi31d00
Data file: DATA:ACHEA09A.D File type: GC / MS DATA FILE Name Info: MENTHOL-2 Misc Info: Operator : JNS Date : 13 Aug 86 5:32 am Instrment: MS_5970 Inlet : GC Sequence index : Als bottle num : Replicate num . TIC of DRTReRCHER09R.0 w 1.0E7~ ~ 9 0E6 . h 6. 0EE a 7.0E6 u c 6.0E6 N a C 5.0EE ~ 0E6 ~ 4 . ¢ 3. 0E6 rc m ma0 w m 2. ®es w v: wrw w m m ~ aom ~ m 1.OEs m h .Y h 0 41 10 20 30 40 50 60 Ttme [m1n.) GRAPH]CSCO [M52] TIC of DATA:ACHEA09A.0 MENTHDL-2 70 60 90 100 T: Scan 5944 (82.910 min) of Z: TIC of DATA:RCHEAOBA.D Y: TIC of DATA:RCHEA09A.D X: TIC of DATA:ACHEA09A.0 Peak# Ret Time Type Width Area Start Time End Time I 7. 182 PH 0,087 49574444 7.145 7.527 2 13. 654 BV 0.033 291297 13.601 13.664 3 13. 717 VU 0.125 3003439 13.664 13.920 4 17. 658 VB 0.037 330441 17.638 17.714 5 21. 956 PU 0.097 9848858 21.834 22.154 6 24. 079 BV 0.076 1470808 23.932 24.168 7 25. 069 UV 0.085 5287454 24.951 25.189 8 31. 712 PU 0.052 602750 31,625 31.728 9 31. 751 VV 0.068 659623 31.728 31.842 10 34. 398 PV 0.429 2419943117 33.585 34.409 11 34. 555 VV 0.121 1023935147 34.409 34.675 12 35. 128 UB 0.048 662888 35.078 35.204 13 44. 005 PV 0.288 2197495418 43.212 44.012 14 44. 041 VV 0.066 429821280 44.012 44.449 15 44. 460 VV 0.038 2660468 44.449 44.514 7& 57. 388 P9 0.200 32021498 57.207 57.921
Page 367: nbi31d00
LIBRARY SEARCH RESULTS Scan 5999 (83.584 min) of DATA:ACHEA07R.D LIGHTS-2 Library file: OATA:TOBACCO.L Library name: TOBACCO AND SMOKE COMPONENTS 1: PYRROLIOINONE-2, N-ETHYL- 2: PYRROLIDIN-2-ONE,1,5-OIMETHYL- 3: COTININE 4: PYRIDINE,3-(I-ET-2-PYRROLIDINYL)- 5: PIPERIDINE,1-ETHYL- 6: N-METHYL ANABASINE (SWW 20) 7: CYCLOHEXENONE-2,4-HYDROXY-3,S,5-TRIMe- 8: 1,5-DIMETHYL-2-PYRROLIDINONE 9: CYCLOPENTANONE,2,5-DIMETHYL- 10: NORNICOTINE,N-ETHYL- (SL 39D) Scan 5999 (83.584 min) 100 ~` 176 100 0 J111291111 4 ~j~ CRS # Library Match Index # Quality 0 1825 6651 0 1378 6543 0 12 6529 0 999 6386 0 1136 6344 0 237 6310 0 1524 6260 0 40 6208 0 1509 6171 0 878 6101 of ORTR.RCHER07R.0 100,I 2 c a R 50 0 01825 PYRROLIOINONE-2, N-ETHYL- 811l I ~I 70 B 113 k137B PYRROLIOIN-2-ONE,1.5-OIMETHYL- 41 11 812 COTININE 42 118 16 B 40 60 60 100 120 CRAPHICSCO [MS2l 176 100 147 50 I 140 160 T:mlll. Z: Scan 5972 (83.237 min) of Y: TIC of DATA:ACHEA07A.D X: Set of 4 MS Scan 5999 (83.584 min) of DATA:RCHEA07A.D LIGHTS-2 m/z abund. m/z abund. m/z abund. m/z abund. 28.15 91 39.15 26 44.15 29 98.15 100 29.25 27 41.25 34 45.15 36 176.15 28 32.15 29 42.15 31
Page 368: nbi31d00
---

Text Control

Highlight Text:

OCR Text Alignment:

Image Control

Image Rotation:

Image Size: