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RJ Reynolds

Journal of the American Medical Association Carried Paper by Dr. Ernest Wynder and Dr. Evarts Graham, Which Concluded, on the Basis of Statistics on the Smoking Habits of 605 Lung Cancer Patients, That "Excessive and Prolonged Use of Tobacco, Especially Cigarettes, Seems to Be An Important Factor in the Induction of Bronchogenic Carcinoma."

Date: 03 Apr 1974
Length: 56 pages
504339438-504339493
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9431 -9573
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LIST
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R&D
Biochem Biobehavioral-Sci Issues
Colby Fg
Assoc Dir Scientific Issues
Jmf
Referenced Document
Cancer by the Carton, by Norr R, Reader's Digest, 521200.
Date Loaded
27 Feb 1998
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Rogers
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Barnes
1rfp17
1rfp52
1rfp53
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Minnesota
1rfp128
Cordova
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Texas
Initial
Named Person
Wynder, E.
Graham, E.
Ochsner, A.
Wynder
Graham
Doll, R.
Hill, A.B.
Hammond, C.E.
Horn, D.
Ama
Dixon, P.R.
Kintner, E.W.
Burney, L.E.
Phs
Tirc
Little, C.C.
Hartnett, T.V.
Blatnik
British Medical Assn
Auerbach, O.
United Press
Friedman
Roseman
British Empire
Eysenck, M.J.
American Heart Assn
Natl Tuberculosis Assn
American Public Health Assn
Univ, O.F. Southern, C.A.
Wisely
Intl Statistical Institute
Royal College, O.F. Physcians
American Assn For Cancer Research
Trentin
Baylor Univ
Usphs
Kissen
Kennedy
Terry
Hueper, W.C.
Us Public Health Service
Wilens
Plair
Ny Veterans Administration Hospital
Lombard, H.L.
Natl Academy, O.F. Science
Passey, R.D.
Royal Marsden Hospital
Seltzer, C.
Harvard Univ
Herrold
Dunham
House, O.F. Delegates
Allen, G.V.
Surgeon General
Sgac
List, O.F. Organizations
Perrone, J.A.
Mercy Hospital
Russek, H.
Meyner, R.B.
Poche
Dixon
Terry, L.
Us Congress
Natl Interagency Council
List, O.F. Health & Education Organ
Nic
Univ, O.F. Md
Foote, E.
Diehl, H.S.
Guthrie, E.H.
President'S Comm, O.N. Heart Disease
Vanderwall
Acs
Ctr
Ftc
Hew
Nci
Ti
Box
Rjr2416
Characteristic
Marginalia
UCSF Legacy ID
ple75d00

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Page 11: ple75d00 Log in for more options!
JULY 12, 1957 U.S. Surgeon General Leroy E. Burney issued stater.!ent saying that "the Public Health Service feels the weifht of the evidence is increasingly pointing in one direction: that excessive snoking is one of the causative factors in lung cancer." Burney reported that a study Eroup-r:ade up of PHS units and two voluntary health orgenizations, after appraisin£ 18 independent studies reported "that lunr, cancer occurs nuch more frequentl;;, among ciEarette smokers than among non-srr.okers and there is a direct relationship between the incidence of lung cancer and the amount sr:oked." IIe added that the Harmond-I[orn study, reported earlier (June 5, 1957) to the American 1?edical Association, "reinforced" the study group's finding. "In the light of these studies, it is clear that there is an increasing and consistent body of evidence that excessive cigarette snoking is one of the causative factors in lung cancer," Burney said. The statement also sr.id that the study group felt "there is no convincing biological or clinical evidence to date to indicate that smoking per se is one of the causative factors in heart disease." PHS took the position that more research is needed before it could take a position on the matter. v~no r~.
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TIRC officials were quick in answering. Dr. Clarence C. Little, then chairnan of the TIP.C's Scientific Advisory Cormittee, pointed out that three years of research by his corunittee "has produced no evidence that cigarette snoking or other tobacco use contributes to the oriein of lung cancer." Dr. Timothy V. Hartnett, chairman of TIPC, cited five independent research studies that tended to refute the cigarette-causation theory. Wide press coverage was given to the TIRC comments.
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JULY 1 8-22 , 1957 Subcommittee on Legal and i:onetary Affairs of the House Comnittee on Government (the "Blatnik Committee") held hearinSs on filter-tip cigarette advertising. (The report of the Blatnik Committee was issued by the parent committee on February 19, 1958. It charged that cigarette manufacturers had deceived the public with false and deceptive advertising of filter-tips, and that the Federal Trade Commission had "failed in its statutory duty to prevent deceptive acts or practices" in filter-ciearette advertising. Anong the scathing charges: "The Federal Trade Commission has failed to approach the problems of false and misleading advertising with vigor and diligence.")
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JANUARY 27, 1958 The British I+edical Association, in a pamphlet issued with its publication, Far.,ilti• Doctor, said "Cirarette smoking is indeed a major cause of lung cancer." The pamphlet Cave figures that one in eight life-long heavy cigarette smokers will die of lung cancer, but only about one in 300 non-smokers will. The panphlet cited a study b;,r Dr. Oscar Auerbach which concluded that "the degree of damaEe to the lungs (examined by autopsy) ...corresponded closel;,~ the number of ciearettes smoked daily." United Press carried coverage which began: "The British Medical Association said today cigarettes are a major cause of lung cancer."
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!'J1RClI 21, 1959 Friedman and Rosenman study suggests that "excessive smoking may be a characteristic" of a behavior pattern but not a causal agent in heart disease. Findings published in Journal of the Ar:ericnr. !'edicnl A=sociation.
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1959 The British rnpire Cancer CrunpeiCn Report says that five years of snoke inhalation by anir.:als failed to produce lunC cancer.
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FEBRU/1RY 5, 1960 Federal Trade Conxiission announced that the tobacco industrY has agreed to end advertising claims thnt certain cigarettes effectivel;~ filter tars and nicotine. FTC chairnan Earl W. Kintner praised the industry, sayine the agreement is a"landMark example of industry-Covernment co- operation in solvinE a pressing problem." Part of the agreement signed by each company stated that the companies vill "avoid using cigarette advertising containing references, direct or implied, to health benefits to be derived from the use of cigarettes..."
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tdAY 111, 1960 In article in British 1'edicnl Journal, noted psycholocist H.J. Eysenck Pnd his associates reported that snokers and non-smokers differ in nany ways, and the kinds of people who sinoke nay be more susceptible to sone diseases.
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OCTOBER 1960 At annual r.~,eeting, Arerican Cancer Society approved resolution (fron its Tobacco-Cancer Corunittee) calling for a Presidential Cor.unission to study tobacco and health question. Resolution called for request to reach the White House by April 1, 1961. ACS to seek cooperation of other agencics in this move. (ACS was successful in getting cooperation: ACS was joined in letter to President by American Heart Association, National Tuberculosis Association, and American Public Health Association.) I
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MARCH, 19G1 Proceedinrs of Arerican /lssocintion for Cancer Research carries paper by University of Southern California scientists, who report they have induced hur.!an-type lung cancer in anirjals by using viruses and artificial sr.iog. (Wisely, et al)

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