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Journal of the American Medical Association Carried Paper by Dr. Ernest Wynder and Dr. Evarts Graham, Which Concluded, on the Basis of Statistics on the Smoking Habits of 605 Lung Cancer Patients, That "Excessive and Prolonged Use of Tobacco, Especially Cigarettes, Seems to Be An Important Factor in the Induction of Bronchogenic Carcinoma."

Date: 03 Apr 1974
Length: 56 pages
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Cancer by the Carton, by Norr R, Reader's Digest, 521200.
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Initial
Named Person
Wynder, E.
Graham, E.
Ochsner, A.
Wynder
Graham
Doll, R.
Hill, A.B.
Hammond, C.E.
Horn, D.
Ama
Dixon, P.R.
Kintner, E.W.
Burney, L.E.
Phs
Tirc
Little, C.C.
Hartnett, T.V.
Blatnik
British Medical Assn
Auerbach, O.
United Press
Friedman
Roseman
British Empire
Eysenck, M.J.
American Heart Assn
Natl Tuberculosis Assn
American Public Health Assn
Univ, O.F. Southern, C.A.
Wisely
Intl Statistical Institute
Royal College, O.F. Physcians
American Assn For Cancer Research
Trentin
Baylor Univ
Usphs
Kissen
Kennedy
Terry
Hueper, W.C.
Us Public Health Service
Wilens
Plair
Ny Veterans Administration Hospital
Lombard, H.L.
Natl Academy, O.F. Science
Passey, R.D.
Royal Marsden Hospital
Seltzer, C.
Harvard Univ
Herrold
Dunham
House, O.F. Delegates
Allen, G.V.
Surgeon General
Sgac
List, O.F. Organizations
Perrone, J.A.
Mercy Hospital
Russek, H.
Meyner, R.B.
Poche
Dixon
Terry, L.
Us Congress
Natl Interagency Council
List, O.F. Health & Education Organ
Nic
Univ, O.F. Md
Foote, E.
Diehl, H.S.
Guthrie, E.H.
President'S Comm, O.N. Heart Disease
Vanderwall
Acs
Ctr
Ftc
Hew
Nci
Ti
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F'nY 27, 1950 Journal of the Anerican ?'edicnl P.s^ocintion carried paper by Dr. Ernest Vlynder and hr. Evarts Graham, which concluded, on the basis of statistics on the smokinF habits of 605 lunC cancer patients, that "excessive and prolonj;ed use of tobacco, especially cigarettes, seems to be an important factor in the induction of bronchogenic carcinoma." The paper Was C.iven little attention in the press. N f w w b f w ~
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nFCEML1t, 1952 Render', T)i(-e^t published article condensed fror.: Christinn Herald, entitled "Cancer by the Carton." Author Ftoy Norr quoted Dr. Alton Ochsner extensively, cited the finding of an English Medical research group that "above the aCe of 45 the risk of developing the disease increases in simple proportion with the ar.:ount srsoked." Also cited: Wynder-Graham stud;, of 1950, quoting conclusion that cigarettes seeM to be important factor in lung cancer. Wynder was quoted as saying: "The more a person sr..okes the Creater is the risk of developing cancer of the lung..."
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riovEAMrF 30, 1953 Tir.:e reported on experiment with cirarette tar painted on backs of nice. P,esearch was done by Wynder and Graharn. Time quoted Dr. GrahaM: "This shows conclusively that there is something in cirarette smoke which can produce cancer. This is no longer merely a possibility. Our experiments have proved it beyond any doubt." Balance of article reviewed charges by Dr. Alton Ochsner, carried comment by other doctors, all unfavorable to cigarettes. Time played up that both Ochsner and Graham have excellent reputations as surgeons.
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JA1•tUl1RY 14 6 1951i 14 tobacco companies and associations of tobacco producers and handlers established the Tobacco Industry P,esearch Committee. The stated purpose of the group: "to conduct research into all phases of tobacco use and its effect on health." Display ads, inserted in major newspapers across the country, told smokers: "Many people have asked us what we are doing to neet the public's concern aroused by the recent reports. Here is the answer: "We are pledging aid and assistance to the research effort into all phases of tobacco use and health. This joint financial venture will of course be in addition to what is already being contributed by individual companies. "In charge of the research activities of the committee will be a scientist of unimpeachable integrity and national repute. In addition there will be an Advisory Board of scientists disinterested in the cigarette industry. A group of distinpuished men from medicine, science and education will be invited to serve on this Board. These scientists will advise the Committee on its research activities." The ads also pointed out that "...eminent doctors and research scientists have publicly questioned the claimed significance of these experinents" and that "...there is no proof that cigarette smoking is one of the causes" of cancer.
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Plow renamed "Council for Tobacco Research - U.S.A.", the resenrch council is "dedicated to the support of the investigation of fundrunental matters relating to a connection between tobacco use and hurian health." An advisory board of scientists directs research policy and pro- grar.ir.aing, with conplete freedon of action. The Board is made up of scientists and physicians who serve in the public interest while retaining their independent affiliations. The research plan is in the forr.i of a grant-in-aid program through which pertinent studies have been financed under independent, es- tablished investigators in medical schools,hospitals, universities and institutes in many sections of the country, Grantees have full freedom of publication, and have produced more than 495 papers in various journals in the past 12 years. More than 230 investigators in over 100 different laboratories have received grants totalinG $9 million. (June, 1966 fiCures)
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Jlrnr: 25, 1951, IBritish t'edi.czl ,Tournnl carried article by Dr. Richard Doll and Prof. A. Bradford 1[i11, chareing that "a significant and steadily risine" lung cancer death rate has been demonstrated among doctors who smoke. Doll and }Ii11 had released preliminary figures in 1952 on their study of 40,£362 physiciars and their smoking habits. The report said lung cancer mortality rate rises as tobacco consumption rises, and reported an increase in deaths attributed to coronary thrombosis "as the amount smoked increases."
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i .TUIIE 21, 19514 Dr. F. Cuyler }[nm-ond and Dr. Daniel Horn, of American Cancer Society, released prelininary firures on two-and-n-half-year- long study of snoking habits of 187,766 rien between 50 and 70 years old. The doctors told the P.merican !'edical Association meeting that "ciCarette sr:okers among men, between 50 and 70, have a death rate higher than non-smokers of the same aCe by as much as 75 percent." "Coronary heart disee.ses and cancer were the diseases primarily responsible for this effect," the At',A news release said. Another reported findine: Heavy cigarette smokers died sooner than light snokers.
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JUNF: 6, 1955 Second, more detailed report on HamMond-Horn Study for American Cancer Society (see June 21, 19511) given at American P'edfcal Association Ileetind. Principal finding reported: Those who stopped sMoking cigarettes have a much lower lung cancer death rate than those who continue to smoke. The study covered 8,105 deaths in the oriCinal study group of 188,000 men aged 50 to 70.
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SFPTEMBEF 22, 1955 The Federal Trade Commission made public its "guides for staff use in evaluating cigarette advertising." The rules, in the words of Paul Rand Dixon (who became chairman of FTC later): "...prohibited representations in cigarette advertisinF or labeling which refer to either xhp presence or absence of any physical effects from cigarette smoking, or which make unsubstatiated claims respecting nicotine, tars, or other components of cigarette smoke, or which in any other respects contain implications concerning the health con- sequences of smoking cigarettes or any advertised brand." (from Senate hearings) The guide lines grew out of conferences with cigarette manufactures which lasted more than a year. In announcing the guidelines, FTC noted that "substantial conformity with the guides took place during the past year while the conferences were in progress." The Commission "expressed hope the industry would continue this voluntary compliance and directed its own Bureau of Consultation to continue consultinF with industry members to assist then in complying." (The FTC's high regard for the cooperative attitude of the industry in this matter was expressed later by FTC Chairman Earl W. Kintner, in announcing the end of the "tar derby" in 1960. He referred to "a relationship of mutual cooperation with the industry," and said "the success of these guides did much to convince the Commission of the value of this program.") ~ r oN
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JUI1~ 1~ , 1957 Final figures and findings of the Hawond-Horn study of 188,000 men 50 to 70 years old released. (see June, 1954 and June 1955). ACS scientists claimed the study showed "a spectacular relationship between the habit (of smoking cigarettes) and lung cancer." Also claimed were findings that ciCarette smoking raised death rates for all causes combined; quitting smoking lowers death risk; and that smoking raises incidence of death from coronary heart disease. Study also implied that snoking was linked with other diseases such as other types of cancer, pneumonia and influenza, and stomach ulcer. This report got extremely heavy press coverage. ~ r ~ J
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JULY 12, 1957 U.S. Surgeon General Leroy E. Burney issued stater.!ent saying that "the Public Health Service feels the weifht of the evidence is increasingly pointing in one direction: that excessive snoking is one of the causative factors in lung cancer." Burney reported that a study Eroup-r:ade up of PHS units and two voluntary health orgenizations, after appraisin£ 18 independent studies reported "that lunr, cancer occurs nuch more frequentl;;, among ciEarette smokers than among non-srr.okers and there is a direct relationship between the incidence of lung cancer and the amount sr:oked." IIe added that the Harmond-I[orn study, reported earlier (June 5, 1957) to the American 1?edical Association, "reinforced" the study group's finding. "In the light of these studies, it is clear that there is an increasing and consistent body of evidence that excessive cigarette snoking is one of the causative factors in lung cancer," Burney said. The statement also sr.id that the study group felt "there is no convincing biological or clinical evidence to date to indicate that smoking per se is one of the causative factors in heart disease." PHS took the position that more research is needed before it could take a position on the matter. v~no r~.
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TIRC officials were quick in answering. Dr. Clarence C. Little, then chairnan of the TIP.C's Scientific Advisory Cormittee, pointed out that three years of research by his corunittee "has produced no evidence that cigarette snoking or other tobacco use contributes to the oriein of lung cancer." Dr. Timothy V. Hartnett, chairman of TIPC, cited five independent research studies that tended to refute the cigarette-causation theory. Wide press coverage was given to the TIRC comments.
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JULY 1 8-22 , 1957 Subcommittee on Legal and i:onetary Affairs of the House Comnittee on Government (the "Blatnik Committee") held hearinSs on filter-tip cigarette advertising. (The report of the Blatnik Committee was issued by the parent committee on February 19, 1958. It charged that cigarette manufacturers had deceived the public with false and deceptive advertising of filter-tips, and that the Federal Trade Commission had "failed in its statutory duty to prevent deceptive acts or practices" in filter-ciearette advertising. Anong the scathing charges: "The Federal Trade Commission has failed to approach the problems of false and misleading advertising with vigor and diligence.")
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JANUARY 27, 1958 The British I+edical Association, in a pamphlet issued with its publication, Far.,ilti• Doctor, said "Cirarette smoking is indeed a major cause of lung cancer." The pamphlet Cave figures that one in eight life-long heavy cigarette smokers will die of lung cancer, but only about one in 300 non-smokers will. The panphlet cited a study b;,r Dr. Oscar Auerbach which concluded that "the degree of damaEe to the lungs (examined by autopsy) ...corresponded closel;,~ the number of ciearettes smoked daily." United Press carried coverage which began: "The British Medical Association said today cigarettes are a major cause of lung cancer."
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!'J1RClI 21, 1959 Friedman and Rosenman study suggests that "excessive smoking may be a characteristic" of a behavior pattern but not a causal agent in heart disease. Findings published in Journal of the Ar:ericnr. !'edicnl A=sociation.
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1959 The British rnpire Cancer CrunpeiCn Report says that five years of snoke inhalation by anir.:als failed to produce lunC cancer.
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FEBRU/1RY 5, 1960 Federal Trade Conxiission announced that the tobacco industrY has agreed to end advertising claims thnt certain cigarettes effectivel;~ filter tars and nicotine. FTC chairnan Earl W. Kintner praised the industry, sayine the agreement is a"landMark example of industry-Covernment co- operation in solvinE a pressing problem." Part of the agreement signed by each company stated that the companies vill "avoid using cigarette advertising containing references, direct or implied, to health benefits to be derived from the use of cigarettes..."
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tdAY 111, 1960 In article in British 1'edicnl Journal, noted psycholocist H.J. Eysenck Pnd his associates reported that snokers and non-smokers differ in nany ways, and the kinds of people who sinoke nay be more susceptible to sone diseases.
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OCTOBER 1960 At annual r.~,eeting, Arerican Cancer Society approved resolution (fron its Tobacco-Cancer Corunittee) calling for a Presidential Cor.unission to study tobacco and health question. Resolution called for request to reach the White House by April 1, 1961. ACS to seek cooperation of other agencics in this move. (ACS was successful in getting cooperation: ACS was joined in letter to President by American Heart Association, National Tuberculosis Association, and American Public Health Association.) I
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MARCH, 19G1 Proceedinrs of Arerican /lssocintion for Cancer Research carries paper by University of Southern California scientists, who report they have induced hur.!an-type lung cancer in anirjals by using viruses and artificial sr.iog. (Wisely, et al)
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APRIL 21, 1961 President's Conference on lleart Disease and Cancer issued report saying in part that "tobacco smoke is an individual form of such (air) pollution, and a particular cancer hazard." The report also said (in the sa:ce section): "The most pronising research lead in cancer causA.tion is that cancer may be the result of the invasion of cells by specific viruses. PSore than a dozen cancer viruses in anir:als have been identified. The question is no longer whether this is also true for Man, but rather how far and for how many cancers of man this applies..."
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SEPTEMBER 7, 1961 Dr. E. Cuyler }iamond reported to International Statistical Institute lteeting in Paris, France, that preliMinary analysis of an American Cancer Society study showed that the amount and depth of inhalation may be the major health risk from smoking. The figures covered 1,085,000 people in the U.S. Hammond said the death rate for those did not inhale was 33 percent higher than non-snokers; for those who inhale sliehtly, 53 percent; for those who inhale moderately, 81 percent; and for deep inhalers, 121 percent. Hammond concluded: "The over-all death rate appears to increase with degree of pulmonary exposure to tobacco smoke; and this is dependent upon the depth of inhalation as well as upon the amount of smoking."
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1•'J1RC1[ 7 , 1962 The Royal College of Physicians (Great Ilritian) issued 70-paee report entitled "Smoking and tlealth", which concluded that: "The evidence that cigarette smoking often has harmful and dangerous consequences is now so convincing that preventive measures are undoubtedly needed." The findings of the report, as summarized by a London newspaper, included these: o"Cigarette smoking is the most likely cause of the recent worldwide increase in deaths from lunE cancer..." o"It is an important predisposing cause in the development of chronic bronchitis." o"It may be partly responsible for the persistence of TB among elderly men. o"It probably incr-ease the risk of dying from coronary heart disease, particularly in early middle age. o"It has an adverse effect on the healing of stomach ulcers, though it does not cause them. o"It may be a contributory factor in cancers of the mouth, throat, gullet and bladder." The report urged the government to take action in these ways: o Intensified education, directed at both young people and the public at large. o Higher taxes on cigarettes o Government-sponsored anti-smoking clinics o Restrictions on advertising by cigarette companies
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o Restrictions on smoking in public places o 1ltore effective restrictions on the sale of cigarettes to children. The report was essentially a review and evaluation by nine physicians of smokinC and health research done to date. Critics charged the report showed many discrepancies, including the iEnoring of other research that tended to dispute the findinGs.
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APRIL, 1962 Proceedi.nf;s of ,~rerican Association for Cancer Research reported that Trentin and his associates at Baylor University had produced lung cancer in hamsters by using virus injections.
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APRIL, 1962 Public Health Peports reports a USPHS study of 163 metropolitan areas found Major differences in lung cancer rates between cities of coMparable size in the same geographic areas.
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APRIL-JUP:E, 1962 Kissen and Eysenck paper in Journr.l of Ps•,chosomatic Re:earch says that psychological factors may be important in lung cancer developnent.
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MAY 239 1962 At Washington press conference, President Kennedy was asked whether he and his advisors agree or disagree with reported findings about tobacco and health, and what, if anything, the govern..^~ent should do about then. He replied: "The matter is sensitive enough and the stock market is in sufficient difficulty to prevent tr.y giving you an answer which is not based on complete information -- which I don't have and, therefore, perhaps I would be glad to respond to that question in more detail next week."
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JUttE 7 , 1962 Surgeon General Terry announced he would appoint an expert advisory committee "to study the evidence, evaluate it and make whatever recommendations may be appropriate." Later that day, at his press conference, President Kennedy was asked about Terry's announcenent. He said the announcement gave Terry's position and that the President supported it. 'rie said the "survey will take some months, maybe going into '63."
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AUGUST, 1962 Dr. W. C. I[ueper (Chief of the National Cancer Institute's Environnental Cancer Section) and his associates auestion overer.,phasis on the cigarette theory of lung cancer causation and cite various possible factors. Article appeared in Archives of °atholof7.%. (Three of Dr. Hueper's five associates are fror Itational Cancer Institute or US Public Health Service).
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NOVEITER 30, 1c)62 Science reports paper by Wilens and Plair of *Iew York Veterans Adninistration Hospital. FindinSs of autopsy studio, of 1,000 cases fails to support causal link between smokine and coronary heart disease.
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DECEGBEP., 1962 Herbert L. Lombard and associates report in Proceedinfs of the 1letionQl AcFder^yof Science that their study of 13,307 ?-iassachusetts death records finds 1unC cancer deaths more than 20 percent overstated. . I r- rn %a
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JULY 21, 1962 Dr. H. D. Passey of Royal Marsden Hospital in London says in Lancet article that neither the mount smoked nor the age when smoking beean deterMines the aCe when lune cancer develops. "If this is true," Dr. Passey says, "tobacco snoke did not act as a carcinoeen."
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. FEBFUARY 23, 1963 Dr. Carl Seltzer, Harvard anthropologist, reported in Journal of the Ariericnn t"edical Association that smokers tend to be larger and heavier than non-smokers, suggesting a constitutional factor in disease.
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Juim, 1963 Herrold and Ihanhar.i of Ilational Cancer Institute report in Cancer Pesearch that they have induced lunQ cancer in animals by feeding chemicals. This suggested that carcinogenic substances nay reach the lung by pathways other than the respiratory tract.
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OCTOF3FR 25, 1963 Rosenman and Fried.^±nn report to Anerican Heart Association that their continuine five-year study covering three cities (in association with five other scientists) indicates that behavior personality patterns can often identify in advance the rian who is likely to suffer a heart attack before the age of 50.
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DECEI-BER !t, 1963 r }Iouse of Delegates, Arerican P"edical Association, adopted ~ rccn.~~'<<.a.~ report frora At'A Board of Trustees ' 9qr"fo-bacco-health research progran to be conducted by AJ•'.A's Education and P.esearch Foundation. A Crar.t of $500,000 authorized by AVA to get study under way.
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JUllE 19, 1963 George V. Allen, President of the Tobacco Institute, told newsmen that most major ciGarette manufacturers had decided to stop all advertising and pronotion on collefe car.:puses. Mr. Allen's full statement: "The industry's position has alWays been that smoking is an adult custom. To avoid any confusion or misconception in the public mind as to this position, a number of member companies of the Tobacco Institute, I understand, have each decided to discontinue college advertising and promotional activities."
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JANUARY 11, 1964 "ScaokinG and Health", the report of the Surgeon Ceneral's Advisor.- Corunittee on Smoking and Health, was released. Its principal finding: "Cigarette smoking is a health hazard of sufficient importance in the United States to warrant appropriate remedial action." Specifically, the report said: o"Cigarette smoking is causally related to lung cancer in man." o"Cigarette smoking is the most important of the causes of chronic bronchitis..." o Cigarettes are related to emphysema, but "it has not been established that the relationship is causal." o"AlthouCh the causative role of cigarette smoking in deaths from coronary disease is not proven, the Committee considers it more prudent from the public health viewpoint to assume that the established association has causative meaning the.n to suspend judp,r:ent until no uncertRint;~ remains." o Pipe smoking "appears" to be causally related to lip cancer. o"CiEarette smoking is a significant factor in the causation of cancer of the larynx." o There is "association", but inadequate data for 8a findinE of causation, between cigarette smokinS and cancer of the esophagus and cancer of the urinary bladder. As for cancer of the stomach, not even association had been shoNn.
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The report nade no judrnent on the beneficial aspects of sMokinF, saying: "The siCr.ificant beneficial effects of sr,.okir.C occur prinarily in the area of r:entn.l health, and the hebit oriEine.tes in a search for contentr..ent. Since no rienas of rensuring the quantity of these benefits is epparent, the Cor..mittee finds no basis for a Judement which would weiCh benefits against hazards of snoking as it r..ay apply to the general population."
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i JANUARY 18, 1904 Just one week after SGAC report, the Federal Trade Commission announced it was setting up "proceedings for trade regulation rules" on what the cor.imission called "unfair and deceptive practices in the advertising or labeling of cigarettes." FTC's proposed rules would have required that all cigarette packages and all cigarette advertising have a warning statement to the effect that cigarettes are dangerous to smokers' health. The rules proposed specific language for the warnings. At the hearings, the tobacco industry was joined by the Association of aational Advertisers, Radio Advertising Bureau, American Plewspaper Publishers' Association, The Chamber of Comr~,erce of the U.S., National Association of Broadcasters, Advertising Federation of America, Grocery Manufacturers of America, ilational Association of Food Chains, and the Television Bureau of Advertising in challenging the FTC's authority to issue mandatory rules.
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FEBRUARY 7, 1961; American t4edical Association's Education and Research Foundation accepted $10 million from tobacco industry to help "finance basic research on the relationship of smoking to disease." The money was offered with the understanding that it was being given without restrictions. According to AA:A press release, "the only condition is that the money be used for research on tobacco and health." {A1dA-ERF had previously announced a"long-ranSe program of basic research to determine if possible how tobacco smoke affects health." The AMA House of Delegates had authorized the project in December, 1963, and had appropriated $500,000 to get the program started. A1iA had appointed five scientists to direct the program, including three who had been members of SGAC.)
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APRIL, 1964 Dr. Joseph A. Perrone of 1'.ercy Hospital in Pittsburgh says in a paper published in Pennsylvania ''edicRl .Tournol that in his study of 1,000 proven cases of lung cancer, nearly half -- 474 -- were found to be non-sr.iokers.
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APRIL 27, 1964 tMajor cigarette Manufacturers announced agreement on CiCarette AdvertisinC Code, applyinr to all advertising of cigarettes. The Code is enforced by an independent administrator, who is inpowered to make violators of the rules pay up to $100.000. Under the Code, advertising nay not make any statement concerning health unless the Adninistrator determines that the statement is "siEnificant in terns of health and is based on adequate, relevant and valid scientific data." In addition, advertising may not "represent that cigarette smokinC is essential to social prominence, distinction, success or sexual attraction," The Code prohibits testinonials fron athletes or celebrities who Might special appeal to persons under 21, as well as ciCarette advertising or promotion irn school, college or university publications or on canpus, The Code also specifies that cigarette advertising r:ay not appear on television or radio progrars, or in publications, directed primarily to persons under 21.
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JurIE, 196h Geriatrics has paper by Dr. Henry Russek. Findinrs included a higher incidence of heart disease among persons who have never sMoked than among those who had stopped smoking. Dr. Russek says snokinG May be only a symptom of occupational stress.
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JUPlE 8, 196b Former N.J. Governor Pobert B. ?teyner was named Administrator of the CiGarette Advertisine Code, with a five-year term. Gov. ldeyner was Civen "complete and final authority to determine whether ciCarette advertising complies with the standards of this Code and to enforce this Code in all other respects," the cigarette nanufactureres said in announcing Meyner's appointment. The Code says no advertising can be used unless submitted to the Adrainistrator and he has found it to be in compliance.
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MARCH, 1964 ; I German scientist Dr. Poche reports his massive study ties lung cancer to occupations exposed to air pollution.
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JUNr^. 22, 1964 FTC promulgates "Trade Regulation Rule" for which hearings were held in 2'.arch, 1964, "Trade Regulation Rule for the Prevention of Unfair or Deceptive Advertising and Labeling of Cigarettes in Relation to the Health Hazards of SMokinf." According to Chairman Dixon, testifying later at Senate Comerce Cor.umittee hearings, "This rule expressed the Commission's determination, for the purpose of preventing future violations of the la1i, of the requirements of the Federal Trade Corrnission Act as applied to marketing of cigarettes in the light of the hee.lth hazards of smoking." Dixon described the rule as providing "that it is an unfair or decentive act or practice...to fail to disclose clearly and prominently in cigarette advertising and labeling that cigarette smoking is dangerous to health and aay cause death from cancer and other diseases." The rule was originally set to go into effect on Jan. 1, 1965 for labels; and July 1, 1965 for advertising. (At the request of the House Commerce Committee, FTC later changed both dates to July, 1965. The rule was, of course, preempted by the Federal labeling act.) f
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JUPlE 23-JULY 2, 1964 House Committee on Interstate and Foreign Commerce held hearings on 10 bills related to advertising and labeling of cigarettes. On first day, Surgeon General Luther Terry told the committee "we are establishing" a National Clearinghouse on Smoking and Health. (This was intended to be a focal point of USPiiS' program of information and education on smoking.) The request for a$1,9 million budget was subsequently rejected by Congress. The second day, FTC chairman Dixon disclosed that his agency has ruled that cigarettes Lsust have a warning label, effective Jan. 1, 1965. A corollary order which required similar warnings in cigarette advertising would go into effect July 1, 1965, he said. (see June 22, 1964) The hearings lasted only four days, and no action was taken. "Due to the imminent adjournment of the Congress, it was apparent that tire would not permit adequate consideration of this problem," the committee's report said (89th Congress report on bill, June 8, 1965). The committee agreed to consider bills next session. The Chairman was directed to request FTC to postpone the effective date of its labeling requirement from Jan. 1, 1965 to July 1, 1965.
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JUNE 2a a , 1964 Formation of the Ilational Interagency Council on Sr.okine and Health was announced. 1'embers include some 16 national agencies and organizations in the fields of health and education. Included as members are such aSencies as: American Association of School Administrators American Cancer Society American Heart Association American Dental Association American Public Health Association Department of Classroom Teachers of the :7EA National Congress of Parents and Teachers National Tuberculosis Association Also included are three governrent agencies: U.S. Children's Bureau U.S. Office of Education U.S. Public Health Service Officers are: Chairman: Fmnerson Foote, former advertising c:an Vice Chairman: Harold S. Diehl, Senior Vice President for Research and 1'edical Affairs, American Cancer Society Secretcry: EuEene It. Cuthrie, Assistant Sureeon General for Operations, U.S. Public Health Service MoRE
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The NIC gets support from the U.S. Government for r.uch of its activities. Conference held t'ay 1-3, 1966, at U. of P+aryland, for example, was "supported by Contract I1o. PH 108-66-131 from the Public Health Service, Department of Health, Education and Welfare." (from folder entitled "Conference Information") NIH receives support in other ways as well. They maintain a mailing address at the National Library of ?Redicine, a PiiS agency. PHS also provides the services of two full-time secretaries. (TestiMony of Emerson Foote, House Committee Hearings, 1965) The services of Dr. Diehl and Dr. Guthrie are donated, too.
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JULY, 1964 Dr. W. C. Ilueper (retired chief of Environmental Cancer Section of National Cancer Institute) says that chemicals introduced into the hurtan environment during the past 30 years should be subjected to systematic bioassay for possible cancer-causinC effects on the respiratory organs. tie argues against "blind acceptance" of the cigarette theory. (article appeared in foreign journal)
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AUGUST 20, 1964 FPC agreed to postpone the effective date of its cigarette package labeling requirement until July 1, 1965, to coincide with its advertising requirement.
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DE CF.N'BER 9, 1964 President's Corur,ission on Heart Disease, Cancer and Stroke issued report stronCly endorsing findings of the SGAC. The Cor.imission reconnended that PIIS be given $10 nillion over a three-year period to undertake a national program of education on the hazards of ciCarette smoking, and the establishment of a network of smoking control clinics. ,,n c ~ ~
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DECEMBER 16, 1964 Gov. 1'eyner announced that the Cigarette Advertising Code Would becone effective January 1, 1965.
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196h In a book on Chronic tlon-Specific Lune Diseases, Dr. Van der Wall of Holland says that such diseases are "an almost obligatory condition" in the production of epidermoid lung cancer. The relationship, sometimes observed in childhood, is "independent of smoking", Dr. Van der Wall says.

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