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THE ROCKEFFLLER UNIVERSITY 123o YO RK A\'ENUI: • NI.W YORK,NEW YOP.F: 10021 Mr. Colin Stokes R. J. Reynolds Industries, Inc. Winst.on--Salem, North Carolina 27102 i)E`aT' Co1 iI7 : February 13, 1980 You will.find enclosed a transcribed version of a letter we have receivea from Dr. James A. Shannon who will participatce in the visit at the Medical. School of the University of Washing- ton in Seattle on February 25th. As you will note, he raises a major question concerning the proposal we have received from the University of California Medical School in San Francisco in relation to slow virus diseases. His dout>ts refer less to the scientific merits of the study than to the fact. that Prusiner's group may be receiving very large support from the Howard Huch_ers_ Medical Foundation. This is an issue which I: will plan to d~.scuss with Dr. Krevans, the Dean of the Medi.cal School at that institution,in the immediate future. Personal.ly, one expects good individuals or groups to have suhstanti al support: from the National Institutes of Health. One of the great virtues of the Reynolds grants lies in the fact that t:hey counterbalance the growing rigidities of government funding. Cm the other hand, support from the Hughes Foundation, if substan- tial., may put the program in a different light. Dr. McCarty and I will plan to visit San Fr.anci.sco'on February 26t.h if, after the discussion with Dr. Krevans, that' still seems desirable. Sincerely, cc:: Mr. H. C. Roemer Mr. J. L. Bacon c-- Frederi-Ek Seitz P.:a . I t al.ked to Dr. Krevans who tel ls me that the 11,ushes support is Licinq~ghasec~"~t''-si.nce the Foundation has decided to drop viruss research. As a result we are trying to arrange to see the group in San Francisco on Tuesday, February 26th. RECEI\IED F E B 19 1980 CONTRIBUTIONS DEPT.