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r Executive Vice President's Report Each year more and more Amcricans are aware of the American Cancer Society, believe in what we are doing, and generously contribute their time and money. This support has made us one of the largest and certainly among the best of volunteer health agencies. And, that is as it should be because we are fighting America's most devastating health problem. But, pre-eminence has the inevitable disadvantage of making us a convenient target for criticism. We expect to have criticism, and we would be surprised if there were none. Since we don't equivocate about cancer, it is understandable that promoters of unproven methods of cancer treatment would seek to discredit the Society. The only sure way to turn off strident critics is to stop working responsibly in the cancer field. A recent criticism of the ACS is that we maintain excessive reserves. This misinterpretation is under- standable because our fiscal operation is unlike most non-profit organizations. It has been our policy from the beginning not to commit funds we don't have in hand. Money contributed during the April Crusade is budgeted for the fiscal year beginning September Ist. In our judgment it is good management to budget only when we know the amount available. This policy has served us well. It has made possible careful and comprehensive planning. It has also meant that we have been able to maintain continuity of program so important to the research investigator. Most voluntary organizations operate differently. They spend money as they raise it. Accordingly, our prudent approach is not suited to the common accounting format used by health and welfare agencies. Our balance sheet should show a "current fund balance" at the end of every fiscal year equal to at least one year's income. This money is not with- held from the support of program activities but is put to work in the fiscal year which begins the next day. We continue to seek methods to assure more prompt and effective utilization of funds. For example, in the past, it has been our policy to permit our Divisions to maintain a contingency reserve, up to 10 percent of the proceeds of their most recent Crusade. In February 1977 our Board of Directors eliminated this reserve provision. We will now try, insofar as is feasible, to eliminate unassigned fund balances at the end of each fiscal year. A second criticism of the ACS is that our "over- head" is far too high because so large a share of what we spend goes for salaries. In fact, the biggest single category of cost in many organizations is the payments they make to peoplc. This is true of a voluntary health agency, a symphony orchestra, a university or a research institute. That we spend a high percentage of our budget for salaries does not mean we have a high overhead. Wc have 2,900 full-titne employees including physicians, nurses, writers, educators, rehabilita- tion therapists, statisticians, managers and scientists -to direct and support the work of 2.5 million volunteers, a ratio of almost 900 to one. That means we can do things money can't buy. The ACS is a. national organization of volunteers who are eager to do something about cancer. The following charts reflect the utilization of the cancer dollar for fiscal 1976. The figures to remember arc these: we spent 11.5% of our income for fund raising and 9.6% for administration. Two of the charts graphically portray this. The third chart shows that 78.9% of the funds were available for program activities. HOW 1975 INCOME WASSPENT IN 1976* Research Patient Services wmmuntiy aervices Available for Budget and Special Project Additions Professional Education I I Public Education Our financial soundness is a source of gr_eat---- strength in the fight against cancer. With reasonable assurance of continued funding, scientists can be more resourceful and imaginative in planning research projects and educators and social workers •-less restricted in developing and implementing cancer control programs. This is why we shall en- deavor to maintain the fiscal health of the American Cancer Society and work with dedication. And, we will do all this because it is in the best interests of the cancer patient. LANE W. ADAMS Executive Vice President *Percentabes relate to spending 1975 income dollars in fiscal year 1975-1976 and vary slightly f rom those on page 20. ~ 0 0 0 S7~ ~ 0 v Ln

used for 1976-1977 programs of research, education, service and related supporting activities covered by approved budgets. Amounts budgeted for special projects by the Boards of Directors are not expendable in the ensuing budget year but are ear- marked for program development over a period not to exceed three years. 5 Current Donor Restricted Funds Current Donor Restricted Funds were restricted by contributors for the following purposes: Research $1,729,656 Other programs 2,653,022 Use in specific geographic locations 2,958,027 $7,340,705 6 Lease agreements The Society's ]ease agreements for office space expire on various dates through December 31, 1985, with aggregate minimum annual rentals as follows: Year ended August 31: 1977 $2,782,223 1978 2,227,767 1979 1,649,278 1980 1,276,993 1981 1,014,906 1982-1986 2,785,100 7 Funds designated by Board of Directors for research support Under the terms of agreements with 21 educational and medical institutions, the Society is obligated to pay the annual stipends of 21 career professor- ships in cancer research, each of which terminates upon the retirement of the approved investigator. Under certain of these contracts the Society has been required to appropriate and deposit with a Trustee $1,061,153 as performance bonds. As of August 31,1976, the estimated aggregate con- tingent liability over the terms of the 21 active contracts, was approximately $8,855,000, exclusive of the liability for fiscal 1977 stipends which has been recorded in the accompanying financial statements. In addition, the Board of Directors has designated legacies in the amount of $2,000,000 to make possible the prompt exploration of unusually promising discoveries in cancer research. These funds are kept in temporary investments, the income from which is allocated to support the research program. 8 Research, professional education and medical project awards payable The Society's awards for research, professional education and medical projects, other than career professorships d iscussed in Note 7, are generally for terms of one to five years. Awards and grants outstanding as of August 31,1976, are payable as follows: Year ended August 31: 1977 $27,306,003 1978 1,363,496 1979 1,017,201 1980 ~ 492,487 1981 115,009 $30,294,196 9 Related party transactions The Society has adopted a policy whereby Board members are disqualified from voting with respect to any Board action affecting their affiliated organizations. Included among the Society's Board members and officers are volunteers from the banking community, who provide valuable assis- tance in the development of policies and programs. Approximately 42% of cash and temporary cash investments were maintained at August 31,1976, in banks with whom Board members were affiliated. Awards and grants are approved by the Boards of Directors, after peer review to establish scientific priorities for funding. In 1976, such awards included approximately $26,000,000 to individuals or insti- t,utions with which Board members from the medical and scientific community were affiliated. ' ® Prior year financial statements i The amounts shown for 1975 in the accom- panying financial statements are presented in accordance with the format recommended by the American Institute of Certified Public Accountants. This fipancial information is included to provide a basis for comparison with 1976 and, other than for the balance sheet, presents summarized totals only. I 26

.L. reasure.L s Repo.E. V The Society is pleased to report once again that our total revenue, fi-otn a1l sources, has reachcd record heights. The Ggure.s speak for themsclves and they are presented on the following pages. Significantly, this is the seventh conSecutive year in which the American Cancer Society has presented combined financial statements with an unqualified opinion from our independent auditors. These two facts are significant in and of them- selves; however, without the dedicated participation of nearly 2.5 million volunteers the Society would not be in a position to report record revenues, nor to exercise prudent and eflicient stewardship over the funds entrusted to it. Not only do ACS volunteers conduct our service, education and fund raising programs, but they also play a vital role in the financial adminis- tration of the Society. To illustrate thee importance of this role, often taken for granted or overlooked, here is what occurs at our National Headquarters. The Finance Committee, charged with setting and administering the Society's overall financial stand- ards and policies, is composed of eleven volunteer Auditors' Report To THE BOARD OF DIRECTORS OF AMERICAN CANCER SOCIETY, INC.: We have examined the combined balance sheet of the American Cancer Society, Inc., National Head- quarters and Chartered Divisions as of August 31, 1976, and the related statements of (a) support, revenue and expenses and changes in fund balances and (b) functional expenses for the year then ended. Our examination was made in accordance with generally accepted auditing standards, and accord- ingly included such tests of the accounting records and such other auditing procedures as we considered necessary in the circumstances. We have previously examined and reported on the financial statements for the preceding year. In our opinion, the accompanying combined financial statements present fairly the financial position of the American Cancer Society, Inc., V members from the medical and lay leadership, and meets a minimum of four times a year. This Committee considers the plans of the Program Departments in financial terms, program thrust, and in relation to overall Society objectives. One of these mectings includes extensive review of the annual budget. In addition, the Finance Committee has two sub-canmittees, the Audit Committee, made up of six volunteers; and the Pension and Endowment Review Committee, which has five volunteers. Furthermore, this process takes place in much ihe same fashion in each and every one of our fifty-eight Divisions throughout the country. It is this direct involvement of volunteers-their commitment of time and experience-working with our dedicated staff that makes the Society work-and I think it works very well. = 9" JOHN S. LAWSON, Treasurer National Headquarters and Chartered Divisions, as of August 31, 1976, and the results of their operations and changes in fund balances for the year then ended, in conformity with generally accepted accounting principles applied on a basis consistent with that of the preceding year. Also, in our opinion, the sum- marized financial information for 1975 presented for cornparative purposes (see Note 10), presents fairly the information set forth therein. New York, N.Y. January 6, 1977. ARTHUR ANDERSEN & 00. 21

r Research The Society awarded a record number of basic research grants in 1976, and welcomed to its staff Dr. Frank J. Rauscher, Jr., former director of the National Cancer Institute. Dr. Rauscher comes to the Society wi th a thorough knowledge of cancer, an unusually clear perspective, and an ability to coordinate many diverse efforts without losing sight of central goals. After five years at the helm of the $700 million government cancer program, he assumes the ACS position of Senior Vice President for Research. The annual ACS investment in research has grown to over $32 million-more than 30 times what it was in 1946 and a 17 percent jump over the 1975 figure. In 1976, the Society issued 542 grants to 149 major institutions in this country, and to scientists working here and abroad. ACS grants are awarded only after careful screen- ing of applicants by scientific review committees, yet they give the researcher a maximum of flexibility in pursuing his work. Report from Dr. Rauscher The American Cancer Society holds a very special position in cancer research: It has the freedom and flexibility of a private organization and the strength of broad volunteer support at every level. The Society can concentrate or diversify its efforts, follow through as well as change direction- in short, it can adapt to meet the most pressing current needs in cancer research. ACS grants are directed toward individually developed programs and those areas of research that other kinds of awards normally do not reach. First, it is most important for the innovative cancer investigator to have in the ACS an alternative source of funds to that of the Federal government. Second, the Society specializes in grants for the advanced training of cancer experts, as well as the development of cancer teaching programs in major institutions. This emphasis on expanding knowledge gives many promising young scientists the boost they need. This is what yields results and saves lives. There has been real progress-in learning about cancer, in developing ways to detect it sooner and in finding more effective and longer-lasting treatments. But cancer is a single term for the most complex group of diseases man has ever sought to control. This is no mean challenge, and it will take a great deal of faith, patience, support and effort. There are many fronts on which progress can come. One of the most promising is the area of cell structure and the body's immune defense system. We now know, for example, that cancer"informa- A6~0 A greatly rnagni fied human lymphoid cell (top), and an ACS researcher at work in his laboratory. - tion"occurs in virtually all human cells. It is usually suppressed, but may be activated by exposure to irradiation, viruses or chemicals. This is very important because it may lead to a ~common denominator in the 100 forms of cancer known today. If we can find out how such a mechanism works, we could at one fell swoop prevent most cancers. Finally we must keep a global view of cancer. More than at any time in history, information is being exchanged that will help determine why a particular cancer is high in one country and low in another. We hope that in time, this will lead to the reduction of cancer throughout the world to the lowest possible levels. 5

Worldwide Fight .Against Cancer : "We have assumed a tnorc dominant international roleincancercotttrol than ever before," Dr. Benjamin F. Byrd, Jr., declared in recapping his completed term as ACS President. The year began with the Society's first Post- graduate Course in Cancer held in two cities of one country-Cairo and Alexandria, Egypt-and ended %vith the establishment of the Society's first inter- national fellowship in clinical oncology. In April, an international symposium on detec- tion ar,d prevention of cancer brought over 2,000 physicians from many countries to New York City. The Biennial meeting of the Council of the Inter- national Union Against Cancer in Toronto in May approved a number of new projects in public and professional education which involve ACS program planning and leadership. In June, a delegation of volunteer and staff officers were the guests of the Ministry of Health of the USSR, visiting a dozen medical and health education institutes in Moscow, Kiev and Leningrad. It was the first such official invitation to a voluntary health agency in the United States. The Ministry of I-Iealth paid all expenses within the Soviet Union, and a generous grant from the Coca Cola Company supported transportation. Dr. Byrd, who led the delegation, said: "We have been able to carry the message of freedom of research around the world, and promote cancer education among physicians, as well as share our public education techniques." This mission emphasized again that the Society's international cancer exchange is definitely a two-way street. Current studies of cancer risk patterns among the varied population groups of the Soviet Union will yield invaluable data in assessing our own. The high point came at year's end with the estab- lishment of the Audrey Meyer Mars International Fellowship in Clinical Oncology. The award will provide a year of advanced training in clinical cancer management in a top cancer institute of the United States for a physician or surgeon from a country where such training opportunities are limited. Supported by Mrs. Mars, it will be a tribute to the dynamic leadership she has given to the Society's Committee to Advance the Worldwide Fight Against Cancer, and to her personal dedication and efforts towards establishing programs of cancer control in many countries of the world. 12 !~; calp-M §P24 . ."14, American Cancer Society poster used in elementary school program on smoking and health. I The commitment and action generated by the 1975 World Conference on Smoking and Health con- tinued through 1976, culminating in TARGET 5-a forceful, five-year ACS campaign to substantially reduce smoking and eliminate harmful ingredients in cigarette smoke. Today, cigarette smoke is responsible for more deaths from cancer than any other single agent, including 80 percent of the 85,000 lung cancer deaths in 1976. TARGET 5 has three main goals: 1. To reduce the number of adults who smoke by at least 25 percent, or 12.5 million smokers. 2. To reduce smoking among young people by at co .L-

~ American Cancer Society, Inc. National Headqw-uters and Chaxtered Divisions Combined Stoai,ernent of Fun,ctional ETenses For the Year Ended August 31, 1976 with Comparative Totals for 1978 Piograin Scrvicrs Rescanch Supporting Scrvicet Mana~cment Public Professional Patient Cortunur.ity ,t Fund Education Education Services xn icis r,eneral Ralcfnj Awards and grants $29,358,975 $ 149,621 $ 4,400,073 ; 167,938 S 3,055,761 $ - $ - Salaries 1,416,594 8,995,657 3,354,190 4,691,935 3,789,753 5,556,826 6,780,121 Employee benefits (Note 1) Payroll taxes Professional fees Supplies Telephone Postage and shipping Occupancy (Note 6) Printing, publications, films, etc. Meetings, including related travel Other travel Specific assistance to 203,948 1,133,861 440,899 596,509 486,695 79,368 623,947 228,964 336,560 265,845 68,881 108,006 24,662 42,724 96,283 72,268 465,387 154,537 228,670 180,023 43,769 610,891 193,014 342,898 220,762 61,029 729,299 262,010 313,710 221,303 179,066 1,321,136 489,585 718,974 461,551 24,921 2,190,466 1,274,498 263,614 244,767 303,815 711,230 684,485 265,664 337,948 153,803 806,709 277,872 385,361 346,081 individuals - - - 5,926,826 196,166 Miscellaneous 21,684 258,028 64,348 61,606 107,658 740,857 793,303 393,304 466,447 991,809 192,796 I-- 321,390 457,291 299,684 502,702 308,458 735,566 1,083,218 867,395 287,726 687,104 399,997 286,124 Total expenses before depreciation and amortization 31,988,121 18,104,238 11,849,137 14,342,989 10,010,596 11,356,497 13,814,699 Depreciation and amortization (Note 1) 92,379 338,315 123,119 182,306 128,729 Total expenses $32,080,500 $18,442,553 $11,972,256 $14,525,295 $10,139,325 $11,635,220 $14,025,665 1976 3,370,432 2,120,876 1,507,733 , 1,979,652 2,006,616 2,314,679 4,408,635 5,940,002 3,744,813 $112,820,814 ~100,961,273 The accompanring notes to combined f nancial statements are an integral part of this statement.

TODAY AND TOMORROW 3,000,000 Americans are alive who have had cancer. - Our commitment to TODAY is the quality of survival... in better treatment and rehabilitation reaching cancer patients wherever they are. Our hope for TOMORROW is to seek to find ways to cure and prevent cancer. . . it is exemplified in our increasing support of research investigation. TODAY and TOMORROW shape the framework of our programs ... the support comes from the volunteers who help make it all happen. t ,~

•M t~ ~ Adult donor (inset) and child are blood-typed. Blood Donor The Society responded this past year to a crucial need for expanding blood donor programs by launch- ing a nationwide effort among ACS volunteers. In February of 1976, the National Board of Di- rectors began examining the problem to determine the most effective approach. In May, a work-study group met to draw up guidelines based on the success of some ACS Divisions which have been operating blood programs for years. Now Divisions across the country are organizing volunteer donor campaigns. Their goal is to provide cancerpatients with all the blood they need at greatly reduced cost. The importance of blood to cancer patients is linked to today's sophisticated methods of treat- ment. Leukemia and other blood-related cancers are being successfully controlled. Part of this success depends on an adequate blood supply. Chemotherapy-the use of anticancer drugs-is perhaps the most promising weapon against cancer today, but it can damage normal blood cells as welll as cancer cells. Whole blood or blood components must be replaced. "Blood," says ACS President R. Lee Clark, M.D., "has become the most vital commodity in cancer therapy." 8 The goal of the nationwide program is to make blood and blood components readily available and less costly to cancer patients. And volunteer blood donors also help to achieve a further goal: improving the quality of donated blood. Donors who are not paid have no reason to conceal histories of diseases that might still affect their blood. In Colorado, where cancer patients use a third of the state's blood supply, the Society has recruited 8,000 volunteer donors. It also has set up a volunteer- operated telephone communications center to handle arrangements. The program costs only $3,000 a year, and has saved patients $250,000 in just two years. Individual savings have ranged as high as $2,000. In Florida, a blood program sponsored jointly by the Society and the University of Florida Inter- fraternity Council can assist a cancer patient any- where in the state. Within five minutes of a request for blood, a donor is located and the patient's hospital contacted. - A Texas program also is getting under way, following pilot blood projects in five areas of the state during 1976. Four mobile blood units are being purchased to facilitate both the collection of blood in outlying parts of the large state, and the prompt processing of the blood for cancer purposes. M

Mammography: Detecting Breast Cancer Early Women with breast cancers detected early by mammography are achieving five-year survival rates as high as 95 percent, compared with only 45-50 percent for more advanced cases. The Society, together with the National Cancer Institute, continued in 1976 to make these valuable low-dose X-rays available to women through the 27 ACS-NCI Breast Cancer Detection Demonstration Projects across the country. The guidelines recommend annual mammograms for all women over the age of 50, because the benefits clearly outweigh any minimal X-ray risk. For women between the ages of 35 and 50, mam- mography is recommended for women who are at higher-than-normal risk of developing breast cancer, because they have: o chronic cystic mastitis, with or without pain o lumps and thickenings in the breast D nipple discharge or other nipple abnormalities D a personal history of breast cancer o a family history of breast cancer on the maternal or paternal side D a f amily history of breast cancer in sisters 10 - Somewhat less serious risk factors include: D early onset of menstruation D no history of pregnancy o first full-term pregnancy at age 30 or older These are only general guidelines, and women who have more than one, or who are uncertain as to their risk level, should consult their doctor on the advisability of mammography. Physicians report that about 80 percent of women between 35 and 50 have one or more of the above risk factors. In the ACS-NCI Breast Cancer Detection Demonstration Projects, 233 breast cancers already have been discovered in women under 50 years of age. Qne hundred of them were detected by mammogra- phy alone. The women under 50 who have no breast problem should still be taught the proper technique of breast self-examination, and urged to perform it regularly each month. . Since breast cancer remains the number one cause of cancer deaths among American women, the Society is constantly seeking the diagnostic tools and treatments which vield the greatest benefit for the least risk.

XOTES TO V OMMXiV! E.1Q1 Jl~'C .~.X~ARML"L /5TA.iLoZb=D= AU.°.~'UST 31 ~ 1976 Accounting policies Standards of accounting and financial reporting As a member of the National Health Council, the Society follows the "Standards of Accounting and Financial Reporting for Voluntary Health and Welfare Organizations" (Revised 1974). These standards are in conformity with the recommenda- tions of the American Institute of Certified Public Accountants. Land, building and equipment and depreciation Land, building and equipment are capitalized at cost or, if donated, at the fair market value at date of receipt. Depreciation is computed using the straight- line method over the estimated useful lives of the assets (buildings-20 to 40 years; office furniture and other fixed assets-2 to 10 years ). Donated materials and services A substantial number of volunteers have donated significant amounts of their time in the Society's program services and in its fund raising campaigns. However, since no objective basis exists for record- ing and assigning values to their services, they are not reflected in the accompanying financial statements. Similarly, the value of space and time contributed by various media for Society educational and fund raising advertisements is not subject to control or measurement and has not been recorded. Donated materials and equipment are reflected as contribu- tions at their estimated fair market value at date of receipt. Principles of combination The accompanying combined financial statements include the accounts of the National Headquarters of the Society, which is a New York not-for-profit corporation, and its 58 Chartered Divisions which are separately incorporated under the laws of the various states and Puerto Rico. All significant intra- Society accounts and transactions have been eliminated in preparation of the combined financial statements. Pension plan The Society has a noncontributory pension plan which covers substantially all employees. Monthly payments are made to the plan trustees in accordance with the Society's policy of funding accrued pension costs. Prior service costs are amortized over the average future service lives of active covered employees. At September 30, 1976, the date of the latest actuarial review, pension fund assets were in excess of the actuarially computed value of vested benefits. Pension expense for the years ended ' August 31, 1976 and 1975, was $3,217,306 and $2,110,516, respectively. Out standing legacies The Society is the beneficiary under various wills and trust agreements, the total realizable amounts of which are not presently determinable. The Society's share of such bequests is recorded when the Society has an irrevocable right to the bequest and the proceeds are measurable. P0 Tax status The Society is a-nonprofit voluntary health agency, exempt from income tax under Section 501(c)(3 ) of the U.S. Internal Revenue Code, and contributions to the Society qualify for the 50 per cent charitable contributions limitation. The Society has been classified as an organization that is not a private foundation and has been designated as a "publicly supported" organization. 3 Allocation of public support Support received from the public by the Divisions is shared with the National Headquarters. In accordance with National policy, which is re- viewed and approved annually by the Board of Directors, 40% of gross contributions, exclusive of approved special purpose gif ts, is allocated to sup- port the National research program and other program activities-for research (25% ), medical grants and fellowships (3 %) and other programs (12% ). Unrestricted legacy income allocated to National (40% ) is used principally in support of the research program. 4 Available funds and budgets To provide continuity of programs and to permit effective budgeting, substantially all activities are financed by public support received during the previous fiscal year. Accordingly, a substantial portion of the available Current Unrestricted Funds reflected in the accompanying balance sheet will be 25 0 0 0 m 0 ~ v

~nr~c i : e Arn.erican Canc er Soriety, Lx><c. ilTationallleadquaricers and Chartered Divisions Support from the Public by Divisions as of August 31, 1976 and 1975 DDivisions 1976 1975 Divtsiona 1976 1975 Alabama $ 854,619 $ 795,766 New York State 5,408,739 4,351,768 Alaska 224,322 174,667 Queens 645,562 436,135 Arizona 953,569 1,341,374 Westchester 603,258 642,670 Arkansas 552,565 498,465 (Total) 18,199,706 11,389,373 California 14,681,829 17,230,398 _ North Carolina 1,635,741 1,409,588 Colorado 1,226,031 1,092,944 North Dakota 431,187 302,749 Connecticut 3,063,314 2,609,930 Ohio 6,896,482 5,923,763 Delaware 464,342 409,737 Oklahoma 837,689 761,055 District of Columbia 1,116,540 1,250,928 Oregon 1,224,189 1,200,318 Florida 5,428,648 5,748,089 Pennsylvania: Georgia 2,836,659 2,435,246 Philadelphia = 1,562,560 1,351,336 Hawaii 1,110,780 1,020,647 Pennsylvania 4,799,396 4,212,321 Idaho 295,210 298,419 Illinois 6,894,008 7,494,553 (Total) 6,361,956 5,563,657 Indiana 2,100,300 1,798,362 Puerto Rico 151,385 171,880 Iowa 1,811,692 1,820,337 Rhode Island 438,801 353,838 Kansas 1,388,454 1,292,320 South Carolina 1,015,873 926,659 Kentucky 1,003,921 1,011,540 South Dakota 289,193 264,371 Louisiana 672,821 635,704 Tennessee 1,824,497 1,272,372 Maine 555,896 499,581 Texas 5,331,358 4,535,792 Maryland 2,082,224 2,136,141 Utah 433,036, 374,523 Massachusetts 2,923,464 3,865,341 Vermont 293,501 353,202 Michigan 4,361,068 3,523,199 Virginia 2,276,733 2,051,764 Minnesota 1,805,617 1,463,351 Washington 1,496,204 1,632,534 Mississippi 616,921 538,566 West Virginia 613,074 549,965 ~ Missouri 2,370,729 2,648,398 Wisconsin: ~ Montana 273,138 317,304 Milwaukee 472,278 473,673 Nebraska 684,632 619,098 Wisconsin 1,448,247 1,318,238 Nevada 253,493 162,929 (Total) 1,920,525 1,791,911 New Hampshire 416,597 403,723 Wyoming 172,457 145,204 New Jersey 3,641,512 3,437,699 826 847 Sub Total: $118 $109,844,419 New Mexico 318,345 266,318 Canal Zone , , 23 669 28,827 New York State: , Long Island 1,804,311 1,363,276 850 516 Grand Total: $118 $109 844,419 New York City 9,737,836 4,596,524 , , , The accompanying notes to combined financial statements are an integral part of this exhibit. 27

r Report from the Presiderkt and C1 iCa1A"man Thomas P. Ulmer Dr. R. Lee Clark Public interest in cancer this past year surged in response to new developments in diagnosis, treat- ment and rehabilitation. The American Cancer Society again contributed substantially to the cancer control effort by awarding more than 500 research grants in 1976, as part of a total research expenditure of over $32 mil•lion. Moreover the Society, recognizing that real progress increases by confronting controversy and examining alternatives, acted decisively to initiate bold new programs in 1976. Among them are the following: Smoking and Health-The ACS, long a pioneer in the field of smoking and health, launched an aggressive, five-year campaign in 1976 to reduce sharply the hazards of this deep-seated habit. Breast Cancer-The Society acted promptly to counter misinterpretation of guidelines issued on the use of mammography. ACS leaders emphasized that while periodic mammograms are not recommended for every woman, they are vital for those over the age of 50, and, indeed, for younger women at high risk to breast cancer. Unproven Methods-For years the Society has main- tained one of the world's largest files on unproven 2 and fraudulent cancer remedies. In the face of accelerated activity by irresponsible and misguided practitioners, ACS Divisions launched a counter- offensive to combat these remedies that deceive cancer pat ients and delay them from getting effective trcatment. Childhood Cancer-ACS-sponsored research has helped to bring about dramatic gains in controlling childhood cancer. In 1976 the Society began estab- lishing committees across the country to deal with thc need for specialized treatment and psychological support unique to this area of cancer control. Blood Donatlon-The proliferating need for blood and blood components in cancer therapy is both a sign of progress in the development of new treatment techniques, and a challenge to meet a crucial need. The Society has initiated a nationwide blood donor effort that both reinforces and seeks to improve existing blood bank programs. We, as physician and businessman, as we11 as American Cancer Society volunteers, know from personal experience the lifesaving role the Society plays in communicating new developments in cancer control to the medical and lay communities. A new telephone information service of the National Cancer Institute is strongly supported by ACS efforts, especially through the use of volunteers to answer telephone!Pand relay vital cancer informa- tion. This service facilitates broader exchange of information between major medical centers and community medical facilities, as well as between physicians and the public. The mass media-newspapers, magazines, radio and television-contributed to the cancer communi- cations effort in 1976 more fully than ever before. The ACS reaches physicians and other medical specialists through professional conferences. In 1976, these dealt with the use of radiation techniques in cancer diagnosis and treatment, and the broad spectrum of cancer research and clinical investigation. In 1977, the Society not only plans medical seminars on topics related to the nursing profession and advances in leukemia therapy, but also a`second major conference on human values and cancer. We at the ACS are deeply committed to the concept that cancer control should benefit the whole person-not only save lives and extend survival, 'but help cancer patients and their families to cope with all aspects of the disease and return to normal, active lives. 11 DR. R. LEE CLARK THOMAS P. ULMER ~ ~ President Chairman m : 0 -4 fi

0 Chamlelil'g DoUars Into the.PXS A ratio of 900 volunteers to 1 paid staff person makes it possible for the ACS to channel its dollars into Program Activity. This then keeps our Fund Raising expenses at very low levels, as they have been for more than 25 years. Our Management and General Expenses have also been kept under strict control. PERCENT OF FUND RAISING AND MANAGEMENT & GENERAL EXPENSES 100% r~ ~ ~y FUND RAI$IIJG MANAGEMENT & GF.NERAL , , 9M - 80% 7 0% 60% tid96 - 40% 30% 2096 10% V`-i PF9 h`: .~ V .~ i 1950 1955 1960 1965 1970 1975 1976 Except for gifts restricted by donors for specific purposes, contributions received in the Annual Cancer Crusade are divided so that 60% is retained by the Divisions for their programs of Public and Professional Education, Service and Rehabilitation for the cancer patient, and for supporting services of Fund Raising, Management and General. A minimum of 25% (actually 28.5% of 1976 expenditures by National and Divisions was for research) is used for the Society's nationally- administered research program; 3% is for a national program of medical grants and fellowships; 12% is for National Office programs including technical and advisory help to Divisions in program planning and support service activities. . Funds bequeathed to the Society, which the testators do not restrict for specific program purposes, are also divided so that 60°/o supports Division programs and 40°'o is for National Headquarters' use, principally, in support of the research program. A1VERICAN CANCER SOCIETY, INC. COMBINED BUDGET 1976-1977 Program Services: Research $ 37,987,000 30.2% Public Education 20,973,000 16.7 Professional Education 13,370,000 10.6 Patient Services 15,615,000 12.4 Community Services 11,130,000 8.8 $ 99,075,000 78.7% Supporting Services: MarPagement and General $ 12,282,000 9.8% Fund Raising 14,411,000 11.5 $ 26,693,000 21.3 % GRAND TOTAL $125,768,000 100.0% BUDGETS In addition to the amounts reflected at right, which have been approved for programs during the coming year, budgets for special projects aggregat- ing $9,879,000 have been approved for program develop- ment during 1977-1979. In February 1977, the National Board budgeted an additional $5,000,000 for grants under a Special Research Development program through fiscal year 1978. 20

Young canccr patient (below) at Children's 1lospiW, Philadc6 phia, has wcit;lrt and height checked. Leukcniic boy's sister (left) visits clinic as part o( effort to involve entire fa?n- ilies in the care of children with cancer. sivc information and rrfcrral sc•rv icc for farnilies of children with cancer. It also provides soine financial support for transhortation, living expenses during out-of-town therapy,and limited funds for drugs and other treatment. The new ACS volunteer blood donor effort (de- scribed elsewhere in this report ) is particularly beneficial to children. Thcircanccr thcrapy frcqucntly calls for large amounts of blood components such as red cells, white cells and platelets. Comprehensive Cancer Centers, funded by the National Cancer Institute and in many cases sup- ported with ACS services, have become specialty facilities for children with cancer. Childhood cancer is neither worse than in the past, nor are more children getting it. The activity in the field stems from the solid progress that has taken place over the last several years. For the first time, long-term control of childhood cancer is a real possibility. Progress is accompanied by problems, and the ACS tries to remedy them directly or through referral. Among the problem areas are the following: • Childhood cancer involves the entire family of the young patient, and ad justment difficulties call for counseling of many kinds. • Therapy depends heavily on drugs, combination treatments and unusually large amounts of blood and blood components. • Hospitals need to gear themselves more to children with cancer-to group young patients by age and provide them.vith recreational equipment rang- ing from rattles to record players.

least 50 percent, or 4.5 milIion smokers. 3. To reducee the toxic elements in cigarette smoke by at least 50 percent. The campaign is being waged on many f ronts simultaneously, and includes the following efforts: DEF' Physicians are being asked to urge their smok- ing patients to stop, and to provide assistance as needed. $+r An "Early Start to Good Health" program is being directed at children in kindergarten through third grade to encourage them to adopt good health habits and avoid hazardous ones such as smoking. UCF- A broad radio and television campaign on smoking and health will include a series of programs produced for the Public Broadcasting System on helping people to quit smoking. C3F- A National Commission on Smoking and Public Policy, composed of national leaders in health, education and other fields will hold public forums throughout the country to develop a public mandate for social action against smoking. 00- The Society is.vorking with legistlative forces and other health organizations for the phasing out of ~60 million worth of government tobacco subsidies each year. During 1976, ACS Divisions conducted more than 1,500 Quit Smoking Clinics and nearly 200,000 Public Education programs on lung cancer, involving films, speakers and discussions. A new international magazine,World Smoking and Health, made its debut in the fall. It is designed to keep open the channels of communication be- tween the quadrennial World Conferences on Smok- ing and Health. Supporting all this activity were several new ACS studies which contributed valuable data to the grow- ing indictment against cigarette smoking as a serious health menace. A survey done for the Society by Yankelovich, Skelly and White, Inc. showed that 27 percent of teen-age girls are smokers-5 percent more than in 1969. Perhaps more significantly, the number of these girls who smoke a pack or more a day had increased fourfold to 39 percent. The smoking habits of teen-age boys have not changed much, but they hold a slight numerical edge over the girls. Part of the reason for heavy smoking by young people was judged to be an all-pervasive smoking environment: Parents who tolerate or even approve of their children smoking, teachers who smoke, schools that provide special smoking rooms for students and teachers, and peer pressure. Among adults, cigarette smoking has declined somewhat over the past decade, according to a report of the Nat ional Clcaringhouse for Smokinfi and I le,ilth. Yet smoking by women has dropped less than that of men, and in some agc brackets women's smoking even increased. A 12-ycar survey released in September provided the first dcfinit ive evidence that smoking low tar and nicotine cigarettes results in lower death rates from lung cancer. The survey was part of the resumption of the Society's huge Cancer Prevention Study. Although ACS researchers recognize that sonie cigarettes may be less hazardous than others, they stress that no cigarette is safe. A study conducted for the Society by The Gallup Organization, Inc. in December indicated that 71 percent of those who smoke a pack or more a day would stop if their doctor urged them to do so. In addition, nearly half of the ex-smokers queried said they would be willing to help others break the habit. Although 53 million Americans still smoke ciga- rettes, 30 million have stopped since the anti-smoking campaign began. The average cigarette today has 60 percent less tar and nicotine than it had 20years ago. Most importantly, there is a definite sign that public attitudes are turning against the habit. Twenty years ago the popular question was: "Aren't you smoking?" Today, it is: "Are you still smoking?" 13

Legacies and Planned Gifts Planned giving is arranged between a donor and the American Cancer Society so that a gift of money or property is irrevocably specified for use by the American Cancer Society. Though the right to use the gift may be deferred, there can be immediate and future tax benefits to the donor. In addition to gifts of cash, a variety of methods for planned giving exists including life insurance, outright or in trust, and appreciated property, such as securities or real estate. An Attorney can advise on how to modernize estate plans and can present ways in which planned giving to the American Cancer Society not only.vill support its work but will also help the donor improve income, lessen taxes and reduce cost of probate. Legacies and bequests are among the most freque-nt-ly used methods of &up--- porting the activities of the American Cancer Society. The simple and direct gift of money or property should state: "I give to the American Cancer Society, Inc., the sum of dollars to be used for the general purposes of the Society." For those interested, a brochure and further information can be had from ACS Divisions. • Memorial Gifts People who have lost close relatives or friends to cancer often wish to make a contribution to the American Cancer Society as a living memorial. Such a gift greatly assists the Society's programs of Research, Edu- cation and Service to cancer patients. Each conxribution is deductible for tax purposes. Each is acknowledged. An appropriate memorial card is sent to the family of the deceased, the amount of the gift not being indicated. Inquiries The AMERICAN CANCER SOCIETY, INC. invites inquiries and will be pleased to respond to requests for information on its progr m activities or finances. The audited ~inancial state- ments-of the Society's Nationai Omce for the year ended August 31, 1976, are also available on request. , . 0 NATIONAL HEADQUARTERS: Y AMERICAN CANCER SOCIETY, INC. 777 Third Avenue - New York. N.Y. 10017 ~ 0 0 0 m oi lu,

CoNMOTS 2 Report from the President and Chairman 3 Executive Vice President's Report 4 Cancer Highlights 5 Research 6 Cancer in Children 8 Blood Donor Program 9 Unproven Methods: A Campaign Against Quackery 10 Mammography: Detecting Breast Cancer Early 11 Cancer Information Network 12 Worldwide Fight Against Cancer 12 Smoking and Health 15 Volunteers for Public Education 16 Cancer Crusade 18 Working with Media 20 Channeling Dollars 21 Treasurer's Report 22 Financial Statements 28 National Officers, House of Delegates 29 Councils and Committees 32 Divisions 33 Legacies, Memorial Gifts, Inquiries i

Cancer Information • Network Acruss the country ACS voluntccrs arc picking up telephones to answer questions about cancer. "I think I have a lump in my breast. What do I do?" "We've just moved into the area and my little boy has leukemia. Wherewill hee get the best treat- ment?" "What is this chemotherapy I've been hear- ing about?" Dealing with such questions is not new for the Society-people have been calling Units and Divisions for years. But now this kind of help is being expanded and improved. The Society, together with the National Cancer Institute and its Comprehensive Cancer Centers, has been building more links over the past year between the public and authoritative sources of cancer information. In some cases, space for "hot-line" telephone centers is donated by ACS Units and Divisions. ACS volunteers answer phones, and toll-free lines are supplied wherever possible. The hotlinc staffs have more complete, up-to-date information at their fingertips than ever before. This effort is part of the Comprehensive Cancer Centers' program of reaching out to community hospitals, medical professionals and the public directly. And it is one of the ways in which the Society and the NCI are cooperating effectively in various parts of the country. These pilot programs will be evaluated to see if they should be more widely developed. In Minnesota, a toll-free WATS line is run by the Minnesota Cancer Council, a newly-formed, non- profit organization initiated by the Minnesota ACS Division and involving nine state medical groups. This information service, housed in the Minnesota Division headquarters in Minneapolis, is manned from 8: 30 a.m. to 4: 30 p.m. five days a week. At other times callers have the option of leaving a message on a telephone answering machine or calling the 24-hour information service of the National Cancer Institute in Bethesda, Md. Complex questions are passed on to cancer specialists and then the volunteer phones the callers back with answers. 5000P U0P3

Honorary Crusade Chairman John Wayne plays a role in the Society's advertising campaign (top left). Former First Lady Betty Ford receives a special Media Award (bottom left). With her are ACS Executive Vice President Lane W. Adams and television's Barbara Walters. Baseball great Hank Aaron , (immediate left) is inter- viewed for an ACS radio spot at Nex, York's Yankee Stadium. 19

r Cancer in Chaldre n The accelerated action against childhood cancer is one of the most promising new areas of ACS work. Cancer strikes many more adults than children. Yet it is the number one disease killer between the ages of 3 and 14. Childhood cancers-affecting such areas as the blood, brain, bones, kidneys and nervous system-have had a poor record of responding to treatment. Now, however, advances in chemotherapy and radiation therapy have sharply altered this dismal picture. More and more children are living longer and in a number of cases are being cured. The Society has been in the forefront of this progress and is striving for further gains. In 1976 it awarded 140 research grants totaling $8.6 million to scientists studying childhood cancer. There is now a National Advisory Committee on Childhood Cancer which is helping Divisions form their own committees and programs. A National Conference on Care of the Child with Cancer is being planned. Some Divisions already have well-established programs. Florida, for example, maintains an exten- Followiug successful bone surgery, Sigrid Gelber has plenty of energy for riding and her pre-ined studies.

't~Torlcirag with Media Maybe We'l1 cure cancer wihouti your help, but dont 'bet your life on it. The way it stands today, one American out o((our will someday have eancer.That means it will strike some member in two out of three American families To change those statistics we have to bring the pn rmi:e of research to everyday rcaliq• And to expand our detection pr.q;ram and techniques And that takes money Lots of moncy Money we wnri t have - unless you help us The American Cancer Society will never give up the fight. Maybe well find the answers even without your help. But don t bet your life on it. American Cancer Societyi, Wr -am uo curr cancer in yuu r hfenmt 18 The Society and the mcdia joined forces in 1976 to alert the public to new information about cancer and new ways of controlling it. The surge of newspaper and magazine articles and the broad range of radio and television programs combined to raise the public's interest in cancer control to its highest point in decades. A key effort was the media's response to a ma jor new ACS study showing increased smoking by teen- agers and young women. Radio and TV personalities gave up cigarettes on their programs to show the public the actual process of breaking a deeply- ingrained habit. The Society assisted such media presentations with literature on smoking and health, and organized Quit Smoking Clinics as a follow-up to articles and broadcasts. ACS TV spots by Green Dolmatch featured entertainer Lola F2tlana telling teens that they don't need cigarettes to be attractive or successful. The use of mammo,graphy examinations for breast cancer became a controversial issue, and the ACS made a special effort to clarify the pros and cons. It stressed the importance of mammography for women over 50, as well as for younger women at high risk to the disease when recommended by their physicians. With more lives being saved from cancer than ever before, the problem of living with cancer assumed greater significance. The Society focused on the issue at the Science N-'riters' Seminar in March at St. Petersburg Beach, Fla. Among the speakers was Orville Kelly, who told how he had coped with cancer and then organized Make Today Count, a nationwide network of self-help groups. After-care is one aspect of the striking new advertising campaign for the 1977 Crusade prepared by Benton and Bowles on a voluntary basis. Other ads feature John Wayne who talks about his fight against cancer. Summing up all this activity were the 16 winners ••of the Media Awards for Excellence in Communica- tions about Cancer. They were chosen from 312 entries in 44 states. The awards were initiated and funded by Mrs. Enid A. Haupt, an ACS Board member.

Cancer Crusade Nineteen seventy-six was a record-breaking year- an expression of public confidence in the role of the Society in cancer research and cancer control. The annual Crusade raised $84,882,450-7.7 per- cent more than in 1975. Legacies amounted to $33,968,066, compared with $31,056,259 the previous year. The combined total of public support for this year was $118,850,516. More than two million ACS volunteers partici- pated in the 1976 effort. . The Society's door-to-door residential Crusade tested educational methods encouraging individuals to help protect themselves against cancer, and ex- plaining the work of the American Cancer Society. The results confirmed that a person-to-person educational approach does lead to better health habits...4oreover, people want to give more gener- ously to the Society when they fully understand its research activities and the lifesaving role that the ACS volunteer plays in cancer control. These findings have led to an expansion of volunteer activity in the Education-Fund Raising Crusade. One growing area of involvement is Special Events-an effort in which volunteers use their 16 imagination and creativity to attract both traditional and new givers. Among the most outstanding of these events was the Walter Hagen Golf Tournament. The Fourth Annual National Walter Hagen Golf`Championship was held December 9-11 at Disney World, Fla. It was the culmination of local tournaments throughout the country, sponsored by 19 Divisions. A total of nearly $600,000 was raised. The American Legion's war against cancer conducted by the Legion and its Auxiliary, with a combined membership of 31/: 1/2mill iraised well over $1 million for ACS-sponsored cancer research, during a year-long drive. Another key fund raising effort is the Federal Employee Program, which provides government workers not only with an opportunity to support the Society, but also with educational programs and ~ cancer screening. 5 During 1977 and in future years, increased em- phasis will be placed on special gifts, memorials and ~ e ; legacies, as well as planned gifts in the form of annuities, pooled income funds and charitable trust designations. oI 0 0 ~ 0 eD

Aixiericaui Cwlcer Soc:iety, Ine. Nation.al Headquarters and Chartered Divisions )mbined Statement of Support, Revenue and Expenses and Changes in Fund Balances For the Year Ended August 31, 1976 with Comparative Zbtals for 1975 UPPORT FROM THE PUBLIC: Contrihutioru- These gifts include bequests of $33,965,066 and special events of $9,816,736 (net of direct expenses of $2,463,319). The cost of raising this money was $14,025,665 or 12% (Note 1) ITHER SUPPORT AND REVENUE: Ir»,cstment income- Pending actual disbursement for budgeted program expenditures, funds are invested in bank savings accounts, certificates of deposit, U.S. Government short-term securities, 1976 1975 . Cuncnt Funds Laud, A lldin and Fnd n t T ta r u uwt en Total Per Cent o Per Cent Ik nor Fquiprnent Funds (No1c 10) Unrestricted Restricted Funds . $105,251,303 $7,874,142 ; 84,343 $5,640,728 1118,850,516 $109,844,419 10,467,187 ; 11,450,900 etc. 9,919,391 547,796 Other income, including $294,120 from U.S. Goverment agencies 183,500 311,684 7,371 Total support and revenue 671,841 115,354,194 8,733,622 91,714 5,640,728 129,820,258 121,967,160 XPENSES: Program services- Research-to support basic scientific studies, clinical investigations and conduct programs seeking new knowledge for the cure of cancer 24,805,801 7,182,303 92,396 Public education-programs designed to inform the public about cancer prevention and symptoms and to encourage periodic physical examinations 17,729,799 366,378 346,376 Professional education-programs designed to improve the knowledge, skills and techniques of the medical and allied health professions in the detection and treatment of cancer 11,366,704 479,706 125,846 Patient services-to provide for information, counseling, nursing and homemaking services, transportation, dressings, and loan closet items 13,644,189 689,850 191,256 Community services-to provide for programs in cancer detection, mass screening, rehabilitation and development of cancer registries 9,716,206 291,835 131,284 Total program services 77,262,699 9,010,072 887,158 Supporting services- Management and general-to direct the overall aflairs of the Society, accounting, personnel and office service activities 11,265,643 81,834 " 287,743 Fund raising-activities to secure increased support from the public for the needs of research, education, service and overall direction 13,670,925 136,723 218,017 32,080,500 :, 28.5% r 27,328,126 27.1% 18,442,553 . . 16.3 17,399,435 17.2 11,972,256 10.6. . 10,313,608 10.2 14,525,295 12.9' .: 13,463,282 13.3 10,139,325 , 9.0 9,056,747 9.0 87,159,929 77.3 11,635,220 . 10.3 ; 10,441,468 10.4 - 14,025,665 12.4 12,960,607 12.8 Total expenses 102,199,267 9,228,629 1,392,918 - 112,820,814 100.0% 100,963,273 100.04 Support and revenue in excess of - (less than) expenses (Note 4) 13,154,927 (495,007) (1,301,204) 5,640,728 16,999,444 . THER CHANGES IN FUND BALANCES: . Acquisition of land, buildings and other fixed assets from current funds (2,043,434) (145,686) 2,189,120 - - 21,003,887 UND BALANCES, beginning of yrar 137,264,684 7,981,398 6,346,094 4,275,243 155,867,419 134,863,532 UND BALANCES, end of year $148,376,177 $7,340,705 $7,234,010 $9,915,971 $172,866,863 $155,867,419 The accompanying notes to combined financial statements and Exhibit I are an integral part of this statement.

Aw Columnist ANN LANDERS, the 1977 National Crusade Chairman, urged her rc:adcrs to practice cancer safeguards. Actor JOHN WAYNE, t he Honorary Crusade Chairman, lost a lung to cancer arid appeared in TV spots as living proof that prompt action against cancer pays off. This message will be stretched across the country as part of the 1977 billboard campaigh. s

Unproven MeVh©V6n. i A Campaign Against Over the past year there was a sharp increase in the promotion of worthless cancer remedies. In response, the Society has initiated a vigorous new program to alert the public and the medical com- munity to these treatments and their hazards. The promotion of unorthodox cancer treatment is not new, but recently promoters of such remedies have joined forces, formed organizations, and are lobbying for state legislation to legalize their products. For years the ACS has maintained one of the most extensive collections of information on unproven methods of cancer management. Now the Society is becoming more than a source of information. It is actively working to educate the public and medical community, and have worthless remedies banned. These unproven methods range from conven- tional-looking drugs to bizarre compresses, diets and machines, but mostpurport to spare the cancer patient from the thirigs he fears most: pain, dis- figurement, expense, uncertainty and death. The Society approaches every potential cancer treatment positively, hoping that a new, effective form of fighting cancer is at hand. Yet it believes that the use of worthless remedies not only squanders the funds of cancer patients and their families, but delays proper treatment that could mean the dif- ference between life and death. In September 1976, a national ACS Cancer Quackery Workshop mapped a broad plan to dissemi- nate information on unproven methods. Ten years ago the Society designed a model state law to effectively control unproven cancer remedies. Now this is being reviewed for possible revisions in view of legislation pending in many states_which could allow the spread of worthless treatments. A few states, such as California, Illinois and Florida, now have strong laws controlling unproven methods. The remedy being fought today most strongly by the ACS and other health organizations is Laetrile, a derivative of apricot pits. It has been tested many times over the years with no beneficial results. In the last several months, the promotion of Laetrile has accelerated, and queries about it received by the ACS national Unproven Methods office have tripled. Unfortunately, unproven methods of cancer man- agement are likely to be a factor to contend with until all cancer is brought under control. In the meantime, they must be checked in three ways: investigation, legislation and education. 9

r 4 CANCER HIGHLIGHTS TREATMENT Hundreds of industrial chemicals are being tested for cancer-causing potential. The work is being supported by both industry and labor. 0 The antibiotic, Adriamycin, has been found to have a broad range of effectiveness in treat- ing human solid tumors. It appears to be the most active single agent in fighting advanced breast cancer. New combinations of drugs together with surgery or radiation therapy are being tested against cancers of the colon-rectum, pancreas, stomach, ovary, bladder, prostate, head and neck. 0 0 ra 0 rm © m Some bone cancer patients now are treated successfully by transplanting sections of bone instead of amputating the limb. 0 0 ® 0 0 9 A 12-ycar ACS study re- leased in September, 1976, provides the first definitive evidence that smoking low tar and nicotine cigarettes results in lower death rates from lung cancer as well as from coronary heart disease. e ® ® ® tl 0 0 m iIm a ® 0 Important developments have been made in assisting cancer patients with trans- fusions of blood components, such as platelets to prevent hemorrhaging and white cells to fight infection. Progress in fighting malig- nant melanoma, a serious skin cancer, is being achieved through the use of anti-cancer drugs together with methods to stimulate the body's immune defense system. The use of drug combina- tions following surgery has raised from 20 to 80 percent the two-year survival rate for patients with osteogenic sarcoma, a bone cancer often occurring in young people. ® m ® © The first promising combi- nation drug treatments for advanced cancers of the colon- rectum and stomach have been reported. 0 ® © Cell-sorting machines under development are expected to scan specimens rapidly and select those with abnormal cells for more detailed analysis. Research has made it possible in many cases to cure I I forms of cancer, ranging from skin cancer to Hodgkin's- Disease. Ten others, such as breast and bone cancer, can be controlled when detected early. High-frequency sound waves are being used instead of X-rays in some cases to locate tumors deep in the body. The technique, known as ultrasound, has fewer side effects. 0 ® ® ~ Chemotherapy combined with surgery and radiation therapy has been found effec- tive in treating 80 to 90 percent of patients with Wilms' tumor, a previously fatal childhood cancer of the kidney. AND RESEARCH RESULTS Recently developed com- puter-assisted axial tomog- raphy (CAT) uses a series of cross-section x-rays to give physicians an excellent view of some internal organs not possi- ble with standard tcchniques. CAT has revolutionized the diagnosis of brain tumors. ~ r.__..~~....,....._... ... ~

National Officers MRS. ALBERT D. 1.ASKER Honorary Chairman of the Board of Directors THOMAS P. ULMER Chairrnan of the Board of Directors HON. JOSEPH H. YOUNG Vice Chainnan of the Board of Directors R. LEE CLARK, M.D. President R. WAYNE RUNDLES, M.D., Ph.D. Vice President and President-Elect BENJAMIN F. BYRD, JR., M.D. Immediate Past President LASALLE D. LEFFALL, JR., M.D. Chairman of the Medical and Scientific Executive Committee SAUL B. GUSBERG, M.D. Chairman of the Medical and Scientific Committee MRS. E. MORGAN MONTGOMERY Vice President PAUL W. WILLIAMS Chairman of the Executive Committee JOHN S. LAWSON Treasurer ALLAN K. JONAS Secretary Past Officer Directors CHARLES R. EBERSOL, Litchfield, Conn. MRS. ROBERT W. HUFF, Rome, Ga. ARTHUR G. JAMES, M.D., Columbus, Ohio A. HAMBLIN LETTON, M.D., Atlanta, Ga. H. MARVIN POLLARD, M.D. Ann Arbor, Mich. JONATHAN E. RHOADS, M.D. Philadelphia, Pa. SAMUEL M. SEEGAL, Brookline, Mass. JOSEPH S. SILBER, (1) Cleveland, Ohio JUSTIN J. STEIN, M.D., Long Beach, Calif. W. ARMIN WILLIG, Louisville, Ky. (1) Deceased 1 /17/77 Honorary Life Members FRANK E. ADAIR, M.D., New York, N.Y. SOL R. BAKER, M.D., Beverly Hills, Calif. ELMER H. BOBST, New York, N.Y. THOMAS CARLILE, M.D., Seattle, Wash. LOWELL T. COGGESHALL, M.D., Foley, Ala. WARREN H. COLE, M.D., Asheville, N.C. MURRAY M. COPELAND, M.D., Houston, Tex. EMERSON FOOTE, Carmel, N.Y. MRS. W. PARMER FULLER, JR., Hillsborough, Calif. MRS. POWELL GLASS, Lynchburg, Va. MRS. ROGER GOODAN, Los Angeles, Calif. MRS. ANNA ROSENBERG HOFFMAN, New York, N.Y. DONALD E. JOHNSON, Flint, Mich. MRS. FORREST E. MARS, The Plains, Va. MRS. R. E. MOSIMAN, Seattle, Wash. HARRY M. NELSON, M.D., Bloomfield Hills, Mich. ALTON OCHSNER, M.D., New Orleans, La. EUGENE P. PENDERGRASS, M.D., Philadelphia, Pa. MRS. JOHN T. PIRIE, JR., Lake Forest, lll. ALFRED M. POPMA, M.D., Boise, Id. J. LEONARD REINSCH, Atlanta, Ga. MATTHEW B. ROSENHAUS, New York, N.Y. HAROLD P. RUSCH, M.D., Madison, Wis. GEORGE E. STRINGFELLOW, Arlington, Va. HOWARD C. TAYLOR, JR.. M.D., New York TRAV IS T. WALLACE,1)allas, Tcx. SHIELDS WARREN, M.D., Boston, Mass. LAWRI.NCE WELK, Pacific Palisades, Calif. FRANCIS J. WILCOX, Eau Clairc, Wis. ASHBEL C. WILLIAMS, M.D., Jacksonville, Fla. DAVID A. WOOD, M.D., San Francisco, Calif. WILLIAM O. WUESTER, M.D., Elizabeth, N.J. House Of Delegates ORA R. ACKERMAN, ED.D., Fort Wayne, Ind. BILLIE L. ARONOFF, M.D., Dallas, Tcx.'t HARVEY W. BAKER, M.D., Portland, Ore.' HUGH R. K. BARBER, M.D., New York, N.Y. JAMES D. BARGER, M.D., Las Vegas, Nev.* IRWIN BELK, Charlotte, N.C. MRS. GORDON BERG, Devils Lake, N.D.* VICTOR G. BLOEDE, Plandome Manor, N.Y.' W. KENNETH BONDS, Oklahorna City, Okla.* HAROLD E. BOWMAN, M.D., Grand Rapids, Mich.* FOSTER J. BOYD, M.D., Wilmington, O. LUTHER W. BRADY, JR., M.D., Philadelphia, Pa.* FRANK E. BRENNAN, Kansas City, Mo. W. LYLE BREWER, Ph.D., Rochester, N.Y.'t MRS. HELENE G. BROWN, Woodland Hills, Calif.*t ROBERT L. BROWN, M.D., Atlanta, Ga.* CHARLES J. BUESING, C.L.U., L.H.D., Monmouth Beach, N.J.* 'Denotes Member, Board of Directors *tDenotes Member, Board & Executive Committee DANIEL BURDICK, M.D., Syracuse, N.Y.* DOROTHY B. BURTON, Salt Lake City, Ut. MISS MARY E. BUSCH, Baltimore, Md.* GROVER L. BYNUM, JR., M.D., Austin, Tex.* BENJAMIN F. BYRD, JR., M.D., Nashville, Tenn.'t JOSHUA F. B. CAMBLOS, M.D., Asheville, N.C.* ROBERT B. CARAWAY, JR., M.D., D.V.M., Wharton, Tex.' DAVID J. CARLSON, M.D., Milwaukee, Wis. JOHN MACK CARTER, New York, N.Y.' R. LEE CLARK, M.D., M.Sc., Houston, Tex.'t STANLEY W. COLE, San Antonio, Tex. SYLVAN C. COLEMAN, New York, N.Y.* RAY S. CRAMPTON, M.D:; Laurel Hollow, N.Y.* JACOB A. DALM, JR., Kalamazoo, Mich ` MILTON F. DARR, JR., Oak Brook, Ill.* JOSEPH A. DEGLMAN, Wauwatosa, Wis. J. S. DEVICK, M.D., Sioux Falls, S.D. ALBERT C. DIDDAMS, M.D., Gallup, N.M. VICTOR C. DIEHM, Conyngharn, Pa.* WILLIAM M. DUGAN, JR., M.D., Indianapolis, Ind. R. DOUGLAS DUPERRAULT, Tampa, Fla. JOHN RIDGEWAY DURANT, M.D., Birmingham, Ala. MRS. ELIZABETH W. ESTES, Lorena, Tex. ROBERT C. EYERLY, M.D., Danville, Pa.* ROBERT J. FALILCONER, M.D., Nor folk, Va.' 1)IANE J. FINK, M.D., Bethe.cda, Md.* FRANK B. FISIIER, Peppcr Pike, O. JACK J. FISHER, Wooster, 0.' WII.LIAM J. FLYNN, M.D., Youngstown, O.* G. ROBI:RT GADBERRY, Wichita, Kan,'t VAN HOLT GARRETT, JR., Denver, Colo. MRS. ORIN G. GEESEY, Kcmmerer, Wyo.' MYRON G. GIBBONS, Tampa, Fla.' JEAN C. GLADDEN, M.D., Harrison, Ark.* CECII. A. GORDON, Paterson, N.J.* DAVID B. GRAY, M.D., Charleston, W. Va. LAMAN A. GRAY, M.D., Louisville, Ky.' PAULA GREEN, Ncsc, York, N.Y.'t WILLIAM GRIFFITHS, Ph.D., Berkeley, Calif.' HAROLD I. GROSSMAN, Minneapolis, Minn. LEWIS W. GUISS, M.D., Los Angeles, Calif.' SAUL B. GUSBERG, M.D., Ncw York, N.Y.'t GEORGE E. HALE, M.D., Anchorage, Ak.' HAROLD A. HARPER, Ph.D., San Francisco, Calif. JOHN R. HARTMANN, M.D., Seattle, Wash.' WILLIAM H. HARTMANN, M.D., Franklin, Tenn ` MRS. ENID A. HAUPT, New York, N.Y.' JOHN C. HAWK, JR., M.D., Charleston, S.C. MRS. DAVID M. HELFELD, Rio Piedras, P.R. RALPH H ESTER, C.L.U., Jackson, Miss.' LARRY HILAIRE, Portland, Ore.*t H. WINSTON HOLT, III, Richmond, Va. J. SHELTON HORSLEY, 111, M.D., Rich~nond, Va. DAVID SMITH HUBBELL, M.D., St. Petersburg, Fla. ROBERT V. P. H UTTER, M.D., Livingston, N.J.* ROBERT W. JAMPLIS, M.D., Palo Alto, Calif. MRS. WILLIAM V. JOHNSON, Los Angeles, Calif.' HENRY P. JOHNSTON, Birmingham, Ala.* ALLAN K. JONAS, Los Angeles, Calif.'t BISHOP ROBERT F. JOYCE, Burlington, Vt.' GUSTAVE L. JUENGLING, III, Cincinnati, O.* B. J. KENNEDY, M.D., Afinneapolis, Minn.' EDWARD L. KING, M.D., Manhattan, Mont. JAMES J. KLAUER, Sioux Falls, S.D.* EDWARD KLETTER, New York, N.Y.* HON. MORGAN M. KLINE, Blootnfield, Conn' GEORGE P. KOECK, M.D., Hopatcong, N.J.* ROBERT M. KRETZSCHMAR, M.D., Iowa City, Ia' C. ROGER KURTZ, M.D., Washington, D.C.' MISS ANN LANDERS, Chicago, Ill.' WILLIAM E. LARSEN, M.D., Leawood, Kan. MRS. ALBERT D. LASKER, New York, N.Y.'t GEORGE J. LAWRENCE, JR., M.D., Bayside, N.Y. JOHN S. LAWSON, Bronxville, N.Y.'t LaSALLE D. LEFFALL, JR., M.D., Washington, D.C.'t LOUIS A. LEONE, M.D., Providence, R.1.!t JAMES B. LEPLEY, D.D.S., Upper Saddle River, N.J.' MRS. BARABARA LEWIS, Austin, Tex.'t EDWARD F. LEWISON, M.D., Baltimore, Md.' CHARLES E. LOCKHART, M.D., Springf eld, Mo.* CHARLES O. LONG, M.D., 28

A2nerican Cancer Society, hx. Nation.;^1 Headt;uarters and Chartered Divisions Combix>led BaLante Shect--A.ugust 31, 1976 and 1975 ASSETS 1976 1975 (Note 10) LIAR)LITILS AND FUND BALANCFS ! 1l76 CU~T FUNDS-UNRESTRICTED Cash: Checking accoimts at National, Research, Professional Education and Medical Project Awards Payable 58 Divisions and their Units s 6,134,192 $ 6,654,656 (Note 8) Savings accounts 13,898,122 7,004,109 Accounts Payable and Accrued Expenses 20,032,314 13,658,765 Total liabilities Temporary Investmerrts, at cost, which approximates market: Certificates of deposit and time deposits 9,635,251 13,012,556 Commitn:ents (Notes 6 and 7) Fund Balances (Note 4): Available for fiscal 1977 and 1976 programs ($123,623,000 budgeted Commercial paper 5,733,179 6,370,257. for 1977) U.S. Government and other securities 60,214,069 22,210,936 Budgeted for special projects 151,602,499 141,593 749 Designated for research support Accrued Interest, Other Receivables and Prepaid Expcnses 6,054,876 , 6,679,720 (Note 7) Total fund balances Educational, Crusade and Service Material, at cost 2,393,528 2,197,571 Deposits of Marketable Securities With Trustee for Research Professorships (Note 7) 1,061,153 1,337,749 $181,144,370 $165,467,554 Cash: Checking accounts Savings accounts Temporary Investments, at cost, which approximates market: Certificates of deposit and time deposits U.S. Government and other securities Accrued Interest and Other Receivables CURRENT FUNDS-DONOR RESTRICTED `. Research Awards Payable ` 1,039,158 $ 916,794 Accounts Payable and Accrued Expenses 1,324,715 1,293,930 Total liabilities 2,363,873 2,210,724 Fund Balance-Restricted~}7y ,386,831 ,847,021 contributors for specific programs or use within specific geographic areas ($2,145,000 budgeted for fiscal 1977 programs) (Note 5) 572,861 2,897,545 4,959,692 5,744,566 238,909 336,642 j 7,562,474 $ 8,291,932 LAND, BUILDING AND EQUIPMENT FUNDS Cash-checking accounts 15,000 $ 10,000 7°io-91i~°io Mortgages Payable Land ($1,593,166 and $1,589,857) and Buildings, at cost, less accumulated depreciation of $711,773 and $497,330 (Note 1) 5,941,804 5,921,981 Fund Balances Electronic Data Processing Equipment, Office Furniture and Fixtures, at cost, less accumulated depreciation of $5,219,496 and $5,122,457 (Note 1) ,600,161 2,886,923 s 9,536,965 $ 8,818,904 Cash-savings accounts Investments, at cost, which approximates market: Certificates of deposit and time deposits U.S. Government and other securities ENDOWMENT FUNDS 380,181 $ 173,047 X'und Balances f 1975 (Note 10) , j S 30,294,196 f 26,447,019 1 2,473,997: 1,755,851 32,768,193 28,202,870 t ;<' i i 135,436,339 122,894,926 ~ . • 9,878,685( 11,032,009 Y 3,061,1333,337,749 l 148t376,177~ 137,264,684 ;181,144,370 $165,467,554 s 209,986 $ 309,434 ~ 11,783 1,100 °.. 221,769 310,534 7}40,705 7,981,398 = 7,562,474 $ 8,291,932 ~ 2~'27,'~5'~ = 2,472,810 7,234,010 6,346,094 ; >l; 9~~S5,q6S $ 8,818,904 ~ 9,91~7)} $ 4,275,243 ~- 1,264,262 966,501 8,271,528 3,135,695 9,535,790 4,102,196 $ 9,915,971 $ 4,275,243 -9,915~',/g $ 4,275,243 The accompanying notes to combined financial statements are an integral part of this balance sheet. Ln 0 0 0 m r 0

Ea ct Lansing, A1 iclt. ROBERT M. I.OVE, North»•ood, N.H. WALTER B. LOVE, JR., Monroe, N.C.* ALEXIS E. LUBCHENCO, M.D., Dcnvcr, C'olu.* JOHN S. LYLE, M.D., Hanover, N.H.* MRS. RALPH A. MANSOLILL, RockviNc Ccntrc, N.Y. MRS. BI:SS MANSUR, Spokane, Wash. DAVID E. MARCELLO,JR., M.D., Brockton, Mass. VICTOR A. MARCIAL, M.D., Rio Picdras, P.R.* DONALD A. MAYEUX, Mantou, la.* ROBERT E. McAFEE, M.D., Portland, Me.* DANIEL O. McCOOK, Brunswick, Ga. RAYMOND A. McCORMACK, JR., M.D., Trcnton, N.J. HON. THOMAS F. McGOWAN, Buffalo, N.Y. FRANK H. McGREGOR, M.D., Oklahoma City, Okla. ROBERT J. McKENNA, M.D., Los Angeles, Calif.' ARSEN h1ELKOIv'IAN, M.D., Montpelier, Vt. NORMAN H. MEYER, Albuqrrcrquc, N.M.* WILLIAM C. MOLONEY, M.D., Boston, Mass.' MRS. E. MORGAN MONTGOMERY, Atlanta, Ga.*t ROBERT C. MOORMAN, Cedar Rapids, Ia. GERALD P. MURPHY, M.D., Snyder, N.Y.'t ALAN S. NELSON, Kennebunk, Me. HOWARD C. NEUCKS, M.D., Urbana, Ill. MRS. ROBERT L. NICKS, Dickson, Te.m. NELSON R. NILES, M.D., Portland, Ore. SPENCER W. NORTHRUP, M.D., Toledo, O. WILLIAM F. NOWLIN, M.D., Gary, Ind.* OMAR T. PACE, M.D., Springfield, Mass.' ELLIOTT PACHTMAN, Union, N.J. CHARLES F. PELPHREY, M.D., Austin, Tex. MRS. R. MARLIN PERKINS, St. Louis, Mo.'t RUSSELL H. PERRY, Dallas, Tex.* INGOLV D. PETERSON, Billings, Mont.* IAN ROBERTSON PHILLIPS, M.D., Fargo, N.D. JOHN D. PIGOTT, M.D., Memphis, Tenn.* DONALD J. PI NALS, M.D., New Rochelle, N.Y. BARBARA B. PORTER, Bethany Beach, Del.* PAUL E. QUINLAN, Lincoln, Neb.* MRS. NANCYANN RABER, Santa Barbara, Calif. JAMES E. REID, Forest Hills, N.Y.* J. PERMAR RICHARDS,JR., Bryn Mawr, Pa. JAMES P. RICKER, F(int, Mich. ANDREW A. RINDLAUB, Portchester, N.Y. PHILLIP G. ROSE, Reno, Nev. GEORGE P. ROSEMOND, M.D., Philadelphia, Pa.* R. WAYNE RUNDLES, Ph.D., M.D., Durham, N.C.'t MRS. VIRGINIA SAMS, Pekin, Ill. EDWARD F. SCANLON, M.D., Evanstort,111. *t JOSEPH C. SCHABACKER, Ph.D., Tempe, Ariz.* STANLEY B. SCHER, Lexington, Ky. EDWARD C. H. SCHMIDT, Ph.D., M.D., Easton, Md. EDWARD J. SCHNEIDER, San Francisco, Calif.' ROBERT J. SCHWEITZER, M.D., Oakland, Calif. JOHN K. SCOTT, M.D., Madison, Wis.' WILLIAM C. SCOTT, M.D., Tucson, Ariz. MRS. WILLIAM J. SEIDEL, Sparianburg, S.C.* STANLEY SHMISHKISS, Sivainpcc'utt, Mass.' III.IZIi1:RT R. SILVERMAN, Red Bank, A'.J.' CIIARLES R. SMART, M.D., Salt Lake City, C/t.* CLA1R A. SNl'DER, I4'yomi.ccing Ilills, Pa. IIARRI' \1'IiBB SOUTHWICK. M.D., I1'innctka, 111. JAM1iS I'ATRICK SPEI.I., M.D., Jackson, Miss. JOIIN H. SI'1CKARD, M.D., Idaho Falls, Id. DONAI.I) E. STADER, M.D., Allentown, Pa. LI:STER G. STL'PPACHER, M.D., Il'yncotc, Pa.* C. CHESTER STOCK, Ph.D., New York, N.Y.* MRS. M. I). STODDARD, Cocur d'Alcnc, !d.* CHARLES 7'. STREETER, M.D., Jacksonville, N.C. GEORGE W. SUMNER, JR., Honolulu, Hawaii STEPHEN WILLIAM SUTHERLIN, Indianapolis, Ind.* CHARLES L. TARLETON, Little Rock, Ark. WILLIS J. TAYLOR, M.D., Mercer Island, Wash.* HAROL.D D. THOMASON, M.D., Lander, Wyo. WILLIAM M. TIPPING, Glcncoe, Ill.* ELDON R. ULMER, Anchorage, Ak. THOMAS P. ULMER, Jacksonville, Fla.'t CECIL H. UNDERWOOD, Wheeling, W.Va.'t DONALD T. WAGGENER, D.D.S., Lincoln, Neb. DONALD R. WALLACE, Madison, Wis. JOHN WALLACE. Needharn, Mass. WINSTON H. WEESE, M.D., New Orleans, La.* SIDNEI' WEINHOUSE, Ph.D., Philadelphia, Pa.* RAYMOND L. WEISBERG, M.D., San Francisco, Calif. FRANK H. WEITZEL, Washington, D.C. MRS. J. YORK WELBORN, Arlington, Va.* WILLET F. WHITMORE, M.D., Plandome, N.Y.* LESLIE W. WHITNEY, M.D., Wilmington, Del. DRAKE W. WILL, M.D.. Honolulu, Hawaii PAUL WHITCOMB WILLIAMS, New York, N.Y.'t JOHN PAGE WILSON, M.D., Atlanta, Ga.* ROBERT C. WOOD, Providence, R.I. HON. JOSEPH H. YOUNG, Baltimore, Md.'t MRS. ALTON ZAMZO'V, Three Rivers, Tex.' ROBERT P. ZANES, ., M.D., Madison, Conn. JOSEPH J. ZAVERTNIK, M.D., Miarni, F/a.'} Council For Research And Clinical Investigatioh Awards ELWOOD V. JENSEN, Ph.D., Chrmn. Ben May Laboratory for Cancer Research, Univ. of Chicago, Chicago, Ill. ROBERT E. HANDSCHUMACHER, Ph.D., Vicc-Chrmn. Dept. of Pharmacology, Yale Univ., New Havcn, Conn. ROSWELL K. BOUTWELL, Ph.D. McArdle Laboratory for Cancer Research, Univ. of Wisconsin, Madison, Wis. JAMES E. DARNELL, M.D. Dept. of Molecular and Cell Biology, Rockefeller Univ., New York, N.Y. HAROLD S. GINSBERG, M.D. College of /'hysicians and Scnt;enns, Columhia llnir., New York, N.I'. CLIPFORD W. GURNEY, M.D. Division of the Biologic•al Sciences, Prit;ker School of Aledicine, Univ. of Chicago, Chicago, /ll. WILLIAM P. JENCKS, M.D. Brandeis lMiv., Waltham, Ma.cs. MORTON M. KLIGERMAN, M.D. Cancer Research and Treatment Ccruer, Univ. of New Mexico, Albuquerque, N.M. li. SHERWOOD LAWRENCE, M.D. Infectious Di.scasc and Irnnuunology Division, Ncw York Univ. School of Medicine, New York, N.Y. WALTER LAWRENCE, JR., M.D. Division of Surgical Oncology, Medical College of Virginia, Richmond, Va. CHOH HAO LI, Ph.D. Hormone Research Laboratory, Univ. of California, San Francisco, San Francisco, Calif. CLEMENT MARKERT, Ph.D. Dept. of Biology, Yale Univ., New Haven, Conn. KIVIE MOLDAVE, Ph.D. Dept. of Biological Chcmistry, California College of Medicine, Univ. of California, Irvine, Calif. RICHMOND T. PREHN, M.D. The Jackson Laboratory, Bar Harbor, Me. DANTE G. SCARPELLI, M.D., Ph.D. Dept. of Pathology, Medical School, Northwestern Univ., Chicago, lll. ROBERT T. SCHIMKE, M.D. Dept. of Biological Sciences, Herrin Lztboratories, Stanford Univ., Stanf ord, Calif. JOHN SPIZIZEN, Ph.D. Dept. of Microbiology, Scripps Clinic and Research Foundation, La Jolla, Calif.. ABRAHAM WHITE, Ph.D. Institute of Biological Sciences, Syntex (U.S.A.), I nc., Research Division, Palo Alto, Calif. Council For Analyqis And Projection • , JOSEPH R. BERTINO, M.D., Chrmn. Division of Medical Oncology, School of Medicine, Stanford Univ., Stanford, Calif. VITTORIO DEFENDI, Ph.D., Vice-Chrmn. Dept. of Pathology, New York Unrv` Medical Center, New York, N.Y. OLIVER H. BEAHRS, M.D. Mayo Medical School, Mayo Clinic, Rochester, Minn. GIULIO J. D'ANGIO, M.D. The Children's Hospital of Philadelphia, Philadelphia, Pa. FRANK J. DIXON, M.D. Scripps Clinic and Research Foundation, La Jolla, Calif. KURT J. ISSELBACHER, M.D. Massachusetts General Hospital, Boston, Mass. GUY R. NEWELL, JR., M.D. National Cancer Institute, Bethesda, Md. DONALD PINKEL, M.D. Dept. of Pediatrics, Milwaukee Children's Hospital, Milwaukee, Wis. FRED RAPP, Ph.D. Dept. of Microbiology, College of Medicine, Pennsylvania State Univ., Hershey, Pa. 29 N O O rn 44 ~~

MAX TISHLER, Ph.D. Dept. of Chemistry, Hatl-Ar.vater Laboratories, Wcslcyan Univ., Middletown, Conn. I. BERNARD \ti'EINSTEIN, M.D. College of Physicians and Surgeons, Columbia Univ., Ncw York, N.Y. Advisory Committee On Biochemistry And Chemical Carclnogenesis EMMANUEL FARBER, M.D., Ph.D., Chrmn. Dept. of Pathology, Univ. of Toronto, Toronto, Ont., Canada BERNARD L. HORECKER, Ph.D., Vicc-Chrmn. Roche Institute for Molecular Biology, Nutley, NJ. EDWARD BRESNICK, Ph.D. Dept. of Biochemistry, School of Medicine, Univ. of Vermont, Burlington, Vt. CLAYTON A. BUCK, Ph.D. The 14'istar Institcrte, Philadelphia, Pa. LEW1S L. ENGEL, Ph.D. Laboratory of Human Rcproduction and Reproductive Biology, Harvard Medical School, Boston, Mass. VICTOR GINSBURG, Ph.D. Laboratory of Biochemical Pharmacology, National Institute of Arthritis, Metabolism and Digestive Diseases, Bethesda, Md. CHARLES C. IRVING, Ph.D. Cancer Research Iaboratory, Veterans Administration Hospital, Memphis, Tenn. NATHAN O. KAPLAN, Ph.D. Dept. of Chemistry, Univ. of California, San Diego, La Jolla, Calif. GERALD LITWACK, Ph.D. Fels Research Institute, School of Medicine, Temple Univ., Philadelphia, Pa. HOWARD S. MASON, Ph.D. Dept. of Biochemistry, Medical School, Univ. of Oregon, Portland, Ore. THEODORE W. RALL, Ph.D. Dept. of Pharmacology, Univ. of Virginia, School of Medicine, Charlottesville, Va. ORA M. ROSEN, M.D. Dept. of Medicine and Molecular Biology, Albert Einstein College of Medicine, New York, N.Y. GORDON H. SATO, Ph.D. Dept. of Biology, Univ. of California at San Diego, La Jolla, Calif. THEODORE L. STECK, M.D. Dept. of Biochemistry, Univ. of Chicago, Chicago, lll. THOMAS E. THOMPSON, Ph.D. Dept. of Biochemistry, Univ. of Virginia, School of Medicine, Charlottesville, Va. MICHAEL A. WELLS, Ph.D. Dept. of Biochemistry, College of Medicine, Univ. of Arizona, Tucson, Ariz. H. G. WILLIAMS-ASHMAN, Ph.D. Ben May Laboratory for Cancer Research, Univ. of Chicago, Chicago, lll. Advisory Committee On Clinical Investigations I-Immunology And Immunotherapy CHARLES F. McKHANN, M.D., Chrmn. Dept. of Surgery, Ma- yo Memorial Building, Univ. of Minnesota, Minneapolis, Minn. JOHN L. ZIEGLER, M.D., Vicc-Chrmn. National Cancer Institute, Bethesda, Md. 30 FRANK L. AI)LER, Ph.D. Div. of Innrumulot;y, St. Jude Chitdren's Rcscurch Hospital, Afemphis, Tcnn. MICHAEL A. BEAN, M.D. Virginia Mason Research Center, Seattle, Wash. FRIF.DRICH DEINHARDT, M.D. Dept. of Microbiology, Rush-Preshytcrian- St. Luke :c Medical Center, Chicago, lll. RICHARD R. LINDQUIST, M.D. Dept. of Pathology, Univ. of Connecticut Health Center, Farmington, Conn. ALBERT F. E.oBUGLIO, M.D. Dept. of Medicine, Ohio State Univ., Columbus, Ohio GEORGE MACKANESS, M.D., Ph.D. Squibb Irutitlcte for Medical Research, Princeton, N.J. ' MALCOLM S. MITCHELL, M.D. Yale Univ., New Haven, Conrt. ELLIOTT F. OSSERMAN, M.D. Institute of Cancer Research, College of Physicians and Surgeons, Columbia Univ., New York, N.Y. GEORGE PIERCE,•M.D. Dept. of Surgery, School of Medicine, Ilniv. of Kansas, Kansas City, Kan. FELIX T. RAPAPORT, M.D. Transplantation and Inmrtmology Division, New York Univ. Medical Center, New York, N.Y. FRED S. ROSEN, M.D. Dept. of Pediatrics, Children's Hospital Medical Center, Harvard University Medical School, Boston, Mass. RAINER STORB, M.D. Fred Hutchiizson Cancer Research Center, Seattle, Wash. OSIAS STUTMAN, M.D. Dept. of Microbiology, Sloan-Kettering Institute for Cancer Research, New York, N.Y. Advisory Committee On Clinical Investigations II-Chemotherapy And Hematology JOHN BENNETT, M.D., Chrmn. Univ. of Rochester Cancer Center, Strong Memorial Hospital, Rochester, N.Y. CHARLES E. MENGEL, M.D., Vice-Chrmn. Dept. of Medicine, Univ. of Missouri, School of Medicine, Columbia, Mo. ROBERT W. BROCKMAN, Ph.D. Dept. of Biochemistry, Southern Research Institute, Birmingham, Ala. PAUL CHERVENICK, M.D. Univ. of Pittsburgh School of Medicine, Pittsburgh, Pa. GERTRUDE ELION, D.Sc. Dept. of Experimental Therapy, Burroughs Welicon:e and Company, Research Triangle Park, N.C. JACK FOX, Ph.D. Sloan-Kettering Institute for Cancer Research, Rye, N.Y. CHARLES M. HUGULEY, JR., M.D. Division of llcmatology and Oncology, Emory Univ. School of Medicine, Atlanta, Ga. RICHARD A. LAURSEN, Ph.D. Dept. of Chemistry, Boston Univ., Boston, Mass. ENRICO MIHICH, M.D. Dept. of Experimental Therapeutics, Roswell I'ark Memorial Institute, Buffalo, N.Y. SEYMOUR PERRY, M.D. Naliuwtl lnstitutcs of Health, Rcthe.%da, Md. ROBERT SII.BER, M.D. Si hool of Medicine, Nen• York 1Miv. Afedicul Center, Ncw )'ork, N.)'. JOSE:PH \'. SIMONE, M.D. Chief, llcrnatology-0rrcology, St. Jude Children's Research Hospital, Men+pleis, Tenn. \S'ILLlAh1 G. THURMAN, M.D. Health Sciences Center, Univ. of Oklahoma, Oklahoma City, Okla. CHARLES W. YOUNG, M.D. Sloan-Kettering Institute for Cancer Research, New York, N.Y. Advisory Committee On Clinical Investigations III-Prevention, Diagnosis And Therapy JOSEPH WIENER, M.D., Chrmn. Dept. of Pathology, Basic Science Building, New York Medical College, Valhalla, N.Y. BRIAN MacMAHON, M.D., Vice-Chrmn. Dept. of Epidcmiology, Harvard Univ. School of Public Health, Boston, Mass. PAUL CALABRESI, M.D. Brown University, Providence, R.l. GERALD L. DeNARDO, M.D. Dept. of Radiology, Univ. of California at Davis, Sacramento, Calif. JAMES FISCHER, M.D., Ph.D. Dept. of Therapeutic Radiology, Yale Univ. School of Medicine, New Haven, Conn. JEROME JAFFE, M.D. Columbia Univ. Neuropsychiatric Institute, Newyork, N.Y. JOHN M. KISSANE, M.D. Dept. of Pathology, Washington Univ. School of Medicine, St. Louis, Mo. JOSEPH LEIGHTON, M.D Dept. of Pathology, Medical College of Pennsylvania, Philadelphia, Pa. ERNEST L. MAZZAFERRI, M.D. Director, Div. of Endocrinology and Metabolism, Ohio State Univ., Columbus, Ohio THEODORE L. PHILLIPS, M.D. Div. of Radiation Oncology, Univ. of California, San Francisco, Calif. MARVIN ROMSDAHL, It7.D., Ph.D. M.D. Anderson Hospital and Tumor Institute, Univ. of Texas, Houston, Tex. BENJAMIN F. RUSH, JR., M.D. Dept. of Surgery, New Jersey Medical School, College of Medicine and Dentistry of A'ew Jersey, Newark, NJ. BETTY G. UZMAN, M.D. Veterans Administration Hospital, Shreveport, La. HALVOR VERMUND, M.D. Dept. of Radiology, Univ. of C.aliforrtia, Irvine, Orange County Medical Center, Orange, Calif. DONALD W. VISSER, Ph.D. Dept. of Biochemistry, Univ. of Souti. •n California School of Medicine, Los Angeles, Calif. Advisory Committee On Institutional Research Grants ROBERT E. PARKS,JR., M.D., Ph.D., Chrmn. Dept. of Biochemical Pharmacology, Div. of Biological and Medical Sciences, Brown Univ., Providence, R.I. JOHN E. PLAGER, Ph.D., M.D., Vice-Chrmn. Roswell Park Memorial Institute, ~

Brrffalo, N.Y. Drptt of Bicrc/rrmistry, Stauford Univ. Dcrelopmental Biology, Univ. of CREED W. ABF.LL, Ph.D. Srhwol of Medicine, Stanford, Calif. Colorado, Boulder. Colo. Dept. of 1lun:rrrr Biological Chemistry and LEROY C. McLAREN, Ph.D. DAVID SCHLESSINGEiR, Ph.D. Gcwctics, Div. of Biochemistry, Univ. of Dept. of Microbiology, School uf Medicine, Dept. of Aticrobiologv. Washington Univ., Texas Medical Branch, Galveston, Tex. Univ. of New Mexico, Albuquerque, N.M. Sclrcol of Medicine, St. Louis, Mo. JOSEPH W. BEARD, M.D. A1.BERT S. MILDVAN, M.D. PATRICIA GAIL SPEAR, Ph.D. Life Sciences Rescarch Laboratories, Biochemistry Div., Institute for Cancer Dept. of Microbiology, Univ. of Chicago, St. Petcrsburg, Fla. Research, Fox Chase, Philadelphia, Pa. Chicago, Ill. IVAN CAMERON, M.D. ARNO G. MOTULSKY, M.D. WILLIE TURNER, Ph.D. Dept. of Anatomy, Univ. of Texas Health Div. of Medical Genetics, Univ. of Dept. of Microbiology, College of Medicine, Science Center at Sart Antonio, Washington School of Medicine, Howard Univ., Washington, D.C. San Antonio, Tex. Seattle, Wash. FRANK YOUNG, M.D., Ph.D. DAVID T. CARR, M.D. CEIARLES C. RANDALL, M.D. Dept. of Microbiolot;y, School of Medicine Mayo Clinic, Mayo Medical School, Dept. of Microbiology, Univ. of Mississippi and Dentistry, Urriv. of Rochester, Rochester, Minn. Medical Center, Jackson, Miss. Rochester, N.Y. JOSEPH E. EGGLESTON, M.D. A. FREDERICK RASMUSSEN, JR., Dept. of Pathutogy, lol:ns Ilopkins Univ., M.D., Ph.D. Baltimore Md School of Medicine Center for Health , . J. LOGAN IRVIN, Ph.D. , Sciences Univ. of California Los Angeles Advisory Committee On Nucleic Dept. of Biochcntistry and Nutrition, Univ. , , , Los Angcles, Calif. Acids And Protein Synthesis of North Carolina School of Medicine, HOWARD V. RICKENBERG, Ph.D. Chapel llill, N.C. National Jcwish Hospital and Research J. THOMAS AUGUST, M.D., Chrmn. PHILIP KRUTZSCH Ph D Cenler, Denver, Colo. Dept. of Pharmacology and Experimental , . . of Anatomy Dept Colle e of Medicine MARTIN SONENBERG, M.D., Ph.D. Therapeutics, Johns Hopkins Univ. . g , , Univ of Arizona Tucson Ariz Div. of Endocrinology, Sloan-Kettering Sclrool of Medicine, Baltimore, Md. . , , . HAROLD M NITO\1'SKY M D Institute for Cancer Research, VINCENT G. ALLFREY, Ph.D., Vicc-Chrmn. . , . . Albert Einstein College of Medicine New York, N.Y. Rockefeller Univ., New York, N.Y. , Yeshiva Univ Bronx N Y HENRY P. TREFFERS, Ph.D. DAVID A. CLAYTON, Ph.D. ., , . . RICHARD L. O'BRIEN M D School of Medicine, Yale Univ., Dept. of Pathology, Stanford Univ., , . . of Pathology Los Angeles County- Dept New Haven, Conn. Stanford, Calif. . , Univ of SorNhern California Cancer FRED T. VALENTINE, M.D. JAMES E. DAHLBERG, Ph.D. . Center L os Angeles Calif New York Univ. School of Medicine, Dept. of Physiological Chemistry, , , , . HUGUES RYSER M D New York, N.Y. Univ. of Wisconsin, Madison, Wis. . . , Dept. of Pathology Cancer Boston Univ FI N N WOLD, Ph.D. JONATHAN A. GALLANT, Ph.D. , . Center Boston Afass Dept. of Biochemistry, Univ. of Minnesota, Dept. of Genetics, Univ. of Washington, , , . MICHAEL SIGEL Ph M D St. Panl, Minn. Seattle, Wash. , . . . RAYMOND GESTELAND Ph.D. Dept. of Microbiology Univ. of Miami , , , School of Medicine, Miami, Fla. Cold Spring Harbor Laboratory, Cold Spring Harbor N Y MURRAY STEIN, D.D.S., M.Sc. Dept. of Oral Surgery and Anesthesia Advisory Committee On Virology , . . LUBOMIR S. HNILICA, Ph.D. , School of Dentistry Case 14'estern And Cell Biology Dept. of Biochemistry and Pathology, , Vanderbilt Univ. School of Medicine Reserve Unitv., Cleveland, Ohio M JESSE STEINFELD D GERALD FINK, Ph.D., Chrmn. , Nashville, Tenn. . , . Medical College of School of Medicine Cornell Univ., Ithaca, N.Y. PHILIP LEDER, M.D. , Virginia Commonx•calth Univ Virginia ARNOLD LEVINE, Ph.D., Vicc-Chrmn. Laboratory of Molecular Genetics, ., , Va Richmond Moffett Laboratories, Princeton Univ., National Institute of Child Care and . , Princeton N.J. Human Development, Bethesda, Md. , WALTER ECKHART, Ph.D. PETER MODEL, Ph.D. The Salk Institute for Biological Studies Rockefeller Univ., New York, N.Y. Advisory Commitlee On , Sart Diego, Calif. GERALD C. MUELLER, M.D., Ph.D. Personnel For Research JOSEPH GALL Ph D Dept. of Oncology, McArdle Laboratory for , . . of Biology Dept Kline Biology Tower Cancer Research, Univ. of Wisconsin, , . , Madison Wis F. E. SHIDEMAN, M.D., Ph.D., Chrmn. Dept of Pharmacology of Afinnesota Univ Yale Univ., New Haven, Conn. ALLAN GRANOFF Ph D , . CHARLES M. RADDING, M.D. . , . , . . Dept. of Internal Medicine School of Medical School, Minneapolis, Minn. Dept. of Virology and Immunology, , Yale Univ New Haven Conn Medicine FRANCIS H. RUDDLE, Ph.D., Vice-Chrmn. Kline Biology Tower Yale Univ St. Jude Children's Research Hospital, Tenn Memphis ., , . , UTTAM L. RAJBHANDARY, Ph.D. , ., New Haven Corut , . GUIDO GUIDOTTI Ph D Dept. of Biology, Massachusetts Institute , . , . . of Technology Carnbridge Mass ELIJAH ADAMS, M.D. Biological Laboratories, Harvard Univ., , , . D Dept. of Biochemistry, School of Medicine, Cambridge, Mass. BRIAN R. REID, Ph. . D i li i Bi h i C U Univ of Maryland Baltirnore Md LEONARD HAYFLICK Ph D v. of forn a, ept. of oc em stry, n a . , , . STEPHEN BAUM M D , . . Dept of Microbiology Stanford Univ Riverside, Calif. , . . Dept. of Medicine and Cell Biology, . , . School of Medicine, Stanford, Calif. CHARLES C. RICHARDSON, M.D. Dept. of Biological Chemistry Harvard Albert Einstein College of Medicine, JOHN J. HOLLAND, Ph.D. , Medical School Boston Mass Yeshiva Univ., Bronx, N.Y. Dept. of Biology, Univ. of California at , , . JOAN A STEITZ Ph D DANE R BOGGS M D San Diego La Jolla Calif , . . . . . . , Univ. of Pittsburgh School of Medicine, , , . KARL G. LARK, Ph.D. Dept. of Molecular Biophysics and Biochemistry Yale Univ. Pittsburgh, Pa. Dept. of Biology, Univ. of Utah, , , New Haven Conn HERMAN N EISEN M D Salt Lake City Ut , . . , . . Center for Cancer Research , . ORLANDO J. MILLER M.D. IRA G. WOOL, M.D., Ph.D. , , Dept. of Biochemistry, Univ. of Chicago Massachusetts Institute of Technology, College of Physicians and Surgeons, , Chicago lll. Cambridge, Mass. Columbia Univ., New York, N.Y. , E. PETER GEIDUSCHEK, Ph.D. GISELA MOSIG, Ph.D. ~ Dept. of Biology, Univ. of California at Dept. of Molecular Biol ogy San Diego, La Jolla, Calif. Vanderbilt Univ., Nashville, Tenn. VINCENT P. }IOLLANDER, M.D., Ph.D. BRUCE NICKLAS, Ph.D. Research Institute for Skeleto-Muscular Dept. of Zoology, Duke Univ., Diseases, Hospital for Joint-Diseases and Durham, N.C. Medical Center, New York, N.}'. KEITH R. PORTER, Ph.D. I. ROBERT LEHMAN, Ph.D. Dept. of Molecular, Cellular and 31

Ir0l1mteC'1.`s for Public E duCation Evcry year tlie Society re aches a largcr purtion of the American public with lifesaving information on the prevention, early detection and treatment of cancer. This past year's public education effort rcached three million more people than in 1975, for a total of 22'.': million. This increase reflects more programs for major national induslrics and Federal agencies such as the U.S. Department of Agriculture and the Social Security Administration. The key to this kind of effective communication is the corps of ACS volunteers, who in 1976 were given a greatly expanded rolee in public education. Now the goal is to double the number of ACS volunteers engaged in public education activities from 100,000 to 200,000 and to focus on involving skilled specializcd voluntcers-nurses, teachers and other professionals. They will lead specific ACS public education projects being expanded through- out the country. Several years ago the Society widened its approach to public education to include "action" efforts directed at changing behavior, so people can protect themselves against cancer. The current drive is to find volunteers best suited to run these four priority programs: 0 Quit smoking clinics need leaders who are ex- smokers with an understanding of group dynamics.  Colorectal programs need coordinators with some medical background and good rapport with popula- tion groups considered at high risk for colon and rectum cancer. 4 0 Classes in breast self-examination (BSE) are best taught by specially trained registered nurses.  The new "Early Start to Good Health" program for kindergarten through third grade students needs the input of professional teachers able to relate well to children. Two major nursing groups-the American Nurses Association and the American Association of In- dustrial Nurses-already have agreed to work closely with the Society in helping teach BSE at the com- munity level. 0

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