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BRITISH AMERICAN TOBACCO Copy Request Form Request Number: 32 Organization: Physicians for a smoke free Canada I Request Details Request Date: .... ./.=.~...~-- .............................. ~)7 ................ o c File Number: .......... ~. .... Box Number: ...................... Page Range: First Page ~ 0 // / O ~" ~ ~" ~" Last Page ~ D ] / ~ ~ ~ ~ ~7 Requested By: (Print Name) Details below will be filled in by Depository Staff Only II Copy Details Copied By:..~~.....~.~ ......................... Date: .... ~.A~./....~... ............ Time: .../.~, ~..~..~ .......... Copy Checked By: ................................. • •me • ••coo•coo•e• •cooed •e Date: .................................... Time: ................. Do•* eee ooe • • III Delivery Details Checked By: ............................. • . .. . . .Date: .............. ..... . Sent By: ........................................ • . Date: ..................... BATCo document for PFSFC 1 March 1999

~tlon of ~ R&D Visit to n~rial Tobacco Ca~da 2~t-2m~ June, ~990 Aims= I. To agree a satisfacto~ h~e for Canad/an partic/pati~ in the Gro~ F=r~ntal ~ ~ra=e. 2. To agree with J-L Mercier the aims and format of the research priorities. 3. To review ITL Project Day. 4. To d/sores strategic ~ to be resolved at technical level in the m~ m~ting in october. i. G~up Resear~ ~ ~L m~e the following ~ ~ating ~ ~ztici~ti~ the Group Fundamental Research ~, largely because of their accountability to other shareholders and to tax authorities. (±) Imperial mint participate in the decisiu~dng process leafing to the programme. (ii) Imper/al mmt be free to opt out of certain projects and be free to apDly the knowledge r~ting ~= ~oj~-~ s~mr~d. Ia~erial, at the time of approval of the ResearCh programme, must be provided with a total budget with b~ by project. (iv) ~ be provided with and approve the formula to share costs between participating countries. These item~ were ~. 0 CD L~ L~ BATCo document for PFSFC 1 March 1999

Grip ~ Rssearc~ ~ ~e decision-maki~ p=ress for ~ ¢~e G~ has ~y ~ prdblems in vi~ of ICL's particular ~-iorities that in =any instances do not re/lect pr~zlties of other CAC c~/es (~or ~ comer~ is generally acb/evahle). A =utoally satisfactory ~ was acjreed based cn ~ t~ Gzo~ ~r~ma ~th an ~cs, ~ w~c~ ~ wish to suppo~. ~e nmdi~ ~ by ~¢L illustrated by a Table teat AL~ bad pregared in advarce based cn the currer¢ ~ Rssean~ CerCre's ~ogr-amme (althco~ ~ only to ill--re the System, ZTL felt that it fairly reflects thsir ~). Pro~ect Title Effort % of Canada Canada ~n Total sumort sumo= Years) Pro- FacCcr for __ ~ Pro~ects (=an yea=) Additives; tz~co dish. 7.2 15.7 - - Other ]IcNae 4.9 10.7 0.8 4.00 Ultl-a-low tar - reed. nic. (~. ~~) 7.8 !~.0 - 0.60 E~S 3.0 6.6 0.2 0.56 ~ow s~ 2.8 6.0 0.2 0.26 Reduced ignition 1.3 2.9 0.2 0.26 New bloassays 3.8 8.3 0.6 2.28 C~=ceensory research 9.7 21.2 - - Novel maC~-ials 5.3 11.6 0.2 1.06 loo.o 8.76 (~) ~e balance of resozrce at FRC i.e. (56.6-45.8) = 10.8 man years is t~dmical services/adm/n, to he spread across all projects. CD CD ta~ ta< C~ BATCo document for PFSFC 1 March 1999

~ m~=~, c~a will ~ a mmu~ in~ ~ ~my are the majority ~ but will not be involved in It.s ~ that if FRC failed to mintain t~ f~r the "Cmmdi~" proJ~es, XTL ~ z~a~t f~ ~m~ati~ Ci.e. ~). Finally it ~s ~ by AIH that despite this innu~tian in ta~ ~ ~ p~j~ts, V2m p~m~le t~at ~ul~s of it ~as agreed that we wmuld seek tm establlsh a f~mlla based on a "c/ub membership" fixed cmmpcrmnt plus a variable el~ ralated to turnover of the individual =m~%ies. ~he aim w~uld be to establish a formula generating ~cr~ cl~e to ~ of 1990 but which wuuld be defensible against ~x a~h=ity ~=y. An a~diticnal item of ~ priarity to ITL ~ to be fizmly of the view that all formal z~Ets fr~ BAT are ~mir m~rty. the ~i~ of zu=tenticm policy ZTL will ex~ore the ~:easibiZ.i.ty ~ (a) ~ a.U. R~seazc~ ~ infinitmm since they have ev/der, ze of heavy usage of su¢~ mterial; ~n) destruying all other documents i.e. ~, ~, after say 5 years (st~bJect to risht to ~ at the He~ of P~D ~~). 2. Markstin= Dir~e~r' s m~tin= was ~ with J-L Me~-ier and Bill Sanders who has A draft briefing note for parT/c/pants by J-L Meruier was modified to lay stress an the fact that whilst CAC's were agreed c~Zfniticm to exclude sim~e Line extensicms and a_~J~ to ide~ oo~ that weze re~ he~ t~ ~-~ ~. zt was aZ.~ acg-eed ~t ~ wou~d format so that Bill Sanders cmn cc~llete a pro-fcrma sheet ea~. ~ w~ld include the c~ny's ~n ~ of priority. At a later stag~ of the meeting the Group ranking • ~ld be ~blish~. ALH will introduce the rationale behind the current FRC projects and give an cutllne of their ~. ~ also ~d be given an ore_--all Group ranking by the m~eting. An ~enda for the me~dng was draft~ '~d all inflation wi~z he ~-patc~d to re~pients next week by J-L ~exv/~. CD 0 BATCo document for PFSFC 1 March 1999

/ 3. pr~-t ~7 A f==~ review of ~ ~ had already b~n a==~U f=W. Temysm, Dan B~n and hls ~ ~ a~ ALff had been im~ted ~ partlc~pate. (or c/asses of ~mds) ~haC R~/~lat=~ ~~ies have hknT.ified as ur~sirahle in smoke. ITL also seek to achieve rea~,:r~ in biological activity of snnke. extl'act/cn cr emzymic trma~Ent of tmbacco e.g. tm~ effective in these treatments it suffers the ~ of ~ar~ in these ~ can be achieved, it is rather • mbtfUl that su~ drastic treatments will ever be truly feasible. Work cn alternative filters cm the other hand, aimed at ~ co anu ~e~r ~ ~, is iooki~ pr~isi~ anU c=z%d be feasible. I ~ the Eoll~ing ~: (i) the ~=k wnl be ver~ ~ rm~/Lng and wnl not give useable results. the ~ ~ m~lificat/nns to d~mical ~m~x~/~/~ is ~ and wiU m~bZy c~mmezuia/ly applicable in time. (i~) c=~=~s~, the w~k ~ bio1~/iual activity currently u~nfined to Am~s test is without f~ticn (other than as a simple screen). e~ems/s m~t await i~nti~icati~n of a m~/ngful battery of bioassays (currently being devalc~ed) beZor~ any useful purpose can be served by the project. 4: strateaic Issues (or RPG meet/zm S//X~ ITL has, for the most part, only a da~st~c there are fewer issues ~ztrlng Grip ~ t~n for ether CAC cm~m~lies. ~se that are impcrtan~ are of a strictly technical nature linked to ~ and ~SO. ~mse will be sent to AIH. c.c. Messrs. B.D. Br-umley N.B. Carmar ALU./SC 27.6.90 CD CD Co BATCo document for PFSFC 1 March 1999