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Product Design

GR&DC Research Programme & Resource Allocation 1984-1986

Date: Nov 1983
Length: 95 pages
517001044-517001138
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Abstract

States the Group Research & Development Center budget has been approved and says research objectives will be assigned differently. Lists budget allocations and organizational staffing charts. Describes and details the stategic objectives of: biological research, smoke research, smoker behavior, flavor research, process research, analysis and test method development.

Fields

Recipient
Ayres, C. Ian (BATCO Group Research & Dev. Centre, UK)
Research Manager, BATCO GR&DC, United Kingdom,
Binns, Richard (BATCO GR&DC Dept. Head )
R. Binns was a BATCO Dept. Head. (N.M. Tobacco Companies Personnel List)
Blackman, Lionel C.F., Ph.D. (BATCo Executive Dir., GR&DC Dir. )
Lionel C.F. Blackman was a BATCO Executive Director, and director of Group Research and Development Center in Southampton, England. (N.M. Tobacco Companies Personnel List)
*Bruell, Edward Alfred Albert (use Bruell, Eric Alfred Albert) (BATCo Chairman, BAT Industries Board of Dir.)
Defense
Davis, N.
de Siqueira, C.J.P. (Scientist at BAT 1975-76)
Scientist at British-American Tobacco Co. Ltd.(?)in 1975-76.
Denton, P.M.
Dunn, Patrick J. (ITC R&D, Montreal, Canada, c 1985-6)
Manager, Analytical Services and Director of Smoking Behavior Research at Imperial Tobacco, Canada. Went by "Pat" or P.J."
Gannaway, Paul H. (BATCo R&D Planning)
Defense
Hardwick, Michael J. (BATCo GR&DC)
Defense
Heard, Alan L. (BAT GR & DC Programs Worldwide Coordinator)
Worldwide coordinator for British American Tobacco's Group Research and Development programmes, around the mid 1980s. BAT Group R&D Manager, Southampton, 1984.
Heath, A.M. (BAT Marketing Director)
BATCo Exec. Director/Marketi
Heywood, D.G. (BAT Finance Exec. Director)
Defense
Hughes, Ivor Wallace, Dr. (CEO Brown & Williamson, TI Executive Committee)
Ivor Wallace Hughes was The Chief Executive Officer of Brown & Williamson Tobacco Company in 1983, also served on the Tobacco Institute Executive Committee in 1983 and was CTR Director 1/28/83.
Kellagher, J.A.B.
Defense
Kohnhorst, Earl E. (BW President of US Business)
Earl E. Kohnhorst was the Director of Research for Brown & Williamson. (PMI's Introduction to Privilege Log and Glossary of Names, Estate of Burl Butler v. PMI, et al, April 19, 1996). In 1994, Kohnhorst was Executive vice president and chief operating officer of Brown & Williamson Tobacco Corp. (LAT 8/2/94). He was also vice president for research, development and engineering, BWT in 1985. (LAT 8/2/94). In a 1/17/85 memo, BWT Corporate Counsel J. Kendrick Wells said he had advised Earl Kornhorst, BWT's VP for research, development and engineering, on the need to prune scientific reports from his files. Wells marked certain reports with an X to designate those that were Deadwood in the behavioral and biological studies area. The Janus studies, secret program of biological research on the effects of smoking which showed tumor growth in animals, should be treated as deadwood. These documents should be segregated, boxed and put in the basement for possible shipment to BAT Industries in England, but no one should make any notes, memos or lists of the documents (LAT 8/2/94). Kohnhorst wrote a 4/26/85 letter re: carbon monoxide . It mentions development of Fact cigarette prototype which was designed to deliver low carbon monoxide. It describes shredded dried stems process which results in carbon monoxide reduction (E. Kohnhorst LT 4/26/85).
Nicholls, R.G., Esq. (BAT Attorney 1975-76)
Nicholls was a attorney for British-American Tobacco Co. Ltd. in 1975-76. R. G. Nicholls, Esq. received copy of "Project Wheat-Part 1 dated 7/10/75 and Project Wheat-Part 2 dated 1/30/76 (Project Wheat 1&2).
Norsworthy, M.
Pritchard, Raymon J.
Richardson, P.A.
Rittershaus, E.
Sanford, Robert A. (BW RD&E VP, Research Director)
Hypothesis
Design changes over time
Changes in cigarette design over the past half century.
Elasticity and Product Control
Health effects
Design changes which have measurably altered health effects of cigarette smoke, both for smokers and nonsmokers.
Inhalation Profile
Are cigarettes designed to cater to individual inhalation profiles?
Introduction of new/unconventional products
Research and development of novel nicotine delivery devices and experimental tobacco designs.
Low-yield cigarettes
Modification of low yield products to assure that adequate levels of nicotine delivery are maintained, and effects of yield changes on toxicity and dependence.
Mainstream constituent yields
Modification of selected mainstream smoke constituents in response to health concerns.
Measuring human intake
Development of scientifically valid procedures for measuring tar and nicotine levels that more accurately reflect human intake.
Measuring overall toxicity
Development of scientifically valid protocols and methods for testing the health and toxicity effects of changes in product design.
Nicotine transport, transfer, and uptake
Design changes which alter nicotine delivery or effect how the product causes and maintains dependence, including transfer of nicotine from tobacco to smoke, and uptake into the body.
Smoke constituent testing
Development of methods for measurement of gas and particulate yields in mainstream and sidestream smoke.
Neurobiology
Sensory targeting
Targeting of smokers through changes in sensory characteristics
Sensory effects
Technologies used to measure, control, or alter sensory effects
Keyword
Animal testing
Brain activity
Brand differences
Carcinogenic (Cancer-causing)
Cardiovascular system (Heart)
Central nervous system (CNS)
Consumer acceptability (Consumer preference)
Delivery modification
Electrophysiological
Environmental Tobacco Smoke ETS
Human testing
Low delivery (Reduced delivery)
Metabolite
Mutagenic
Neuropharmacology (Electrophysiology)
Receptor, brain, and CNS effects (EEG, trigeminal response, etc.)
Nicotine delivery (Smoke nicotine or nicotine yield)
Patents
Physiological effects
Satisfaction
Sensory response
Tar/Nicotine ratio (Nicotine/Tar Ratio or T/N ratio)
Total particulate matter (TPM or Tar)
toxicology
Trigeminal chemoreception (Trigeminal nerves)
Additive
Eugenol
Smoke Constituent
Aldehydes
Arsenic
Cadmium
Cobalt
Hydrogen cyanide (HCN)
lead
Mercury
Nickel
Nitric oxides
Nitrosamines (N-nitrosamines)
Design Component
Blended leaf (BL)
Bright casing (Flue-cured casing)
Bright tobacco (Flue-cured tobacco)
Burley casing
Burley tobacco
Green leaf
Plasticizer
Selective filtration
Operation/Project
Project RIO
Named Organization
B.A.T. Cigarettenfabriken GmbH (B.A.T. Cigarettenfabriken GmbH)
B.A.T. Cigarettenfabriken GmbH
Birmingham Hospital
British Industrial Biological Research Association
British Standards Institute
British-American Tobacco Co Ltd (British-American Tobacco Co. Ltd.)
British-American Tobacco Company Limited was a operating group under B.A.T. Industries P.L.C. in 1985.
CAC (China-American Cigarette Co - Assoc with RJR)
1994 China-American Cigarette Co - Assoc with RJR
Coresta (Industry-affiliated Int'l scientific/research group)
An international organization whose objective is "to improve cooperation in scientific research and tobacco." Consists of 186 member companies/institute from 54 countries, including tobacco, paper and filter companies, and universities engaged in tobacco research.
Group Research and Development Center (Research center for BATco in Southampton, England)
Imperial College
ITL, Canada
Papworth Hospital
Rubber and Plastics Research Association
Shirley Institute
Surrey University
Tobacco Advisory Council (TAC) (International industry advisory council)
Tobacco Advisory Council
Subject
Blends (Design)
Cancer (Health Effects)
Cardiovascular Effects (Health Effects)
CNS/Brain (Effects)
Filters (Design)
health effects
Low Yield Cigarettes (Products)
Metabolites (Measures)
Novel Cigarette Devices (Products)
Pharmacology (Effects)
Pressure Drop (Design)
secondhand smoke
Sensory Effects—Taste (Effects)
Smoke Nicotine (Measures)
T/N Ratios (Measures)
Test/Animal Subject (Testing)
Test/Consumer Preference (Testing)
Test/Inhalation (Testing)
Test/Smoke Condensate (Testing)
Test/Toxicity (Testing)
Transfer to Smoke (Measures)
Ventilation (Design)

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Page 1: 0000009608
BRITISH-AMERI CAN TOBACCO COMPANY lIMITED IR&DC RESEARCH PROGRAMME & RESOURCE ALLOCATION 1984-1986 :(a) GROUP R&D PROGRAMME ,~,,,-~:~ ' :i:(b) PRODUCT TECHNOLOGY AND TECHNICAL SERVICES :;i,,:!: ,~.-. :>:(SUMMARY ONLY) ," , :. ,;:i'.:i,/ D I STR i BUTi ON: • 6. A.M. Heath/j.A.B. Kellagher • t . , 1" E.A.A. Bruell • R.J. Pritchard !i~. 4. ~':D.G. Heywood/P.A. Richardson ~- L.C.F. Blackman 8. , N. Davis - ::9 .... J.P. Sikkel 10. M. Norsworthy 11. 12. 13. 14. 15.- R.A. Sanford E.E. Kohnhorst P.J. Dunn E. Rittershaus F. Seehofer 16. C.J.P. de Siqueira 17. P.M. Denton 18. R.G. Nicholls 19. A.L. Heard 20. C.I. Ayres 21. M.J. Hardwick 22. R. Binns 23. P.H. Gannaway RESTRICTED November 1983. MAY BE OPENED AND SEEN ONLY BY THE ADDRESSEE AND PERSONS AUTHORISED BY THE ADDRESSEE
Page 2: 0000009608
CONTENTS FOREWORD SUMMARY OF RESOURCES ALLOCATED TO THE GROUP R&D PROGRAMME AND TO PRODUCT TECHNOLOGY AND TECHNICAL SERVICES TOTAL GR&DC STAFF ALLOCATION (1984) ORGANISATION • GR&DC PROFESSIONAL STAFF PAGE i ii iii iv v&vi GROUP R&D PROGRAMME 01 Biological Research 02 Smoke Research 03 Smoker Behaviour 04 Flavour Research 05 Process Research: - Physical Properties of Tobacco - Chemistry of Processing & Expansion Studies - Novel Cigarette Technology 06 Analysis and Test Method Development 1 11 23 35 45 53 59 67 Specialist Resources Appendix I PRODUCT TECHNOLOGY & TECHNICAL SERVICES Financial Sugary Appendix II CA :D F.w CA
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FOREWORD The GR&DC get proposals were the BATCO Board in November, !98: kis docume a year ago, .:with the major differences that_project organograms are shown against ~ork area and the bar-charts are aced by descriptions of tasks and timescales. Programme has been formul in the light of discussions the Research Conference in August, 1983. iMajor agreed changes to current1983-85 Work Programme are:;!:~!,i~i~ii.~i:~:~,i~:,~it:~i?~r,;.~:c,!~,,/,:,.:'~ Iter~Nitrosamines;Sidestreamand Combustion research are In a new Work Area 02, Smoke Research .... c~,,. g;smok'e"xero£Gi:;P~{;iogical"andPharmacoibgical ;/!: are now a new Work Area 03, Smoker Behaviour. md Biotechnology Expansion, and Novel Cigarette Technology research are now )ed within Work Area 05, Process Research ...... Control and Physical Test Method Development is removed tom the,Work Programme. Any future activities on physical test methods will probably be incorporated into Work Area 06, Analysis and Test Method Development. aCtivitie'sare~piit between Product Technology ,(application) and Group R&D Programme (research). Psychology • esearch is included in Work Area 02, Smoke Research, and in Area 03, Smoker Behaviour.- , , .... i~!,~,~ii~,,::/~!,~I~ ~arate resources areailocated to Future Technologies, Special Projects, Smoking Issues and International and Specialist Committees. ~se activities are summarised in Appendix I. ~ ~:~./:C~! /~i!~ ::.,-.,~::;~: balance of the GR&DC Work Programme i.e. that which is not funded by Group companies on an 'allocation - formula' basis, is shown in in the sister document entitled "Product Technology and Technical ~::~i Services - Programme and Resource Allocation 1984". This was approved ~;~.,~In content by the~i~n~J~be~and a summary of the budget -:- is given in Appendix FI. '- November, 1983 1. Ob
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SUMMARY OF RESOURCES ALLOCATED TO THE GROUP R&D PROGRAMME AND TO PRODUCT TECHNOLOGY AND TECHNICAL SERVICES Group R&D Programme Biological Research Smoke Research Smoker Behaviour Flavour Research Process Research: Physical Properties of Tobacco Chemistry of Processing & Expansion Studies Novel Cigarette Technology Analysis & Test Method Development Specialist Resources Totals Product Technology & Technical Services+ Total++ Direct Effort* Graduate Assistant Years Years 3 14 6 12 7 9 8 13 S 5 5 3 I 5 2 6 4 41 67 '12 12 • 53 79y' Total Revenue** ( 000) 1984 1985 1986 869 11224 1152 1112 616 731 433 407 539 76~0 7083 7200 7200 I.:Z-~ 1 2151 2100 2100 9234 9300 9300 I All revenue figures are in 1984 terms. ~'~ NOTES: *These figures show the number of man-years specifically allocated to the Work Programmes. Seconded Personnel, Administration and Technical Support Staff are excluded. **In addition to the cost of Direct Effort, the Total Revenue includes both specific costs (e.g. Contracts, Leaf, Travel) and an allocation of Administration, Site Services, Depreciation, etc. +Details in sister document. ++Staff numbers for the Group R&D Programme do not necessarily correspond with the names given on pages v and vi - because in some cases fractional staff effort has been allocated from or to Product Technology & Technical Services. © t983 British American Tobacco Co. Ltd. This rnus¢ not be copied or sllnwn to un2uthofised persons. Ul h.w ¢=
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• Technical Supporl ::.Management Support Hon-Technical Supportc (Allocated) chnology & Technical Services Effort 71 . 208 ~AND TOTAL NOTES: 1. ; i-.....~ .. 279 Man Years -.. . . Technical Support provided by Ceni~ral Analytical Service, Statistics & Computing and Sample Manufacture. Non-Technical Support from Accounts, Administration, Engineering/ Workshops, Catering, Security, Stores and Library/Information.
Page 6: 0000009608
"4." ~Patents ',=~ ..... ~,: Planning - " " K.J.H. P.H. Gannaway ,6. ~nith RESEARC"I R.R. Baker .~:~ BEHAV TOUR Read " • :"'T '-'*'~;~f~ - ...."" ':~'~ RESEARCH R.A. Crei ]in Future Technologtes :K.D. Kilburn Spect al Projects H,G, Horsewel 1 - -. -:::~;. -. ..... -Physics R.G. llook -Chemistry -Expansion R.W. Hedge ~(~:?~-~ ,. . -tiovel Cigarette Technolog) O.A. Luke "Secondary --,Automation R.G. Bryant SCIENTIFIC SUPPORT .. R. Binns , --, , • r . o DEVE I.OPHEIIT .II.F.D. D~mond I Library and --Information F. Marsh __Computing D.B. Mullen r, - SI[E AD~INISTRAT ION ~,J. Hardwick Admi ni st rati on JEngineering -'-R. Smurthwa!te iPersonnel --M.S.R. Douglas sample " " " . . .. --Manufacture J.F.K. McCreadie Statistics "--E.B. Wilkes Sensory --Testing B.C. Harding Flavour Manufacture PRODUCT I TECHNOLOGY J & TECHN ICA[J SERV ICES 'J Product . --Development T, Hirji ".: Psychology ' -'-R,P, Ferris Sidestreaml --Special ,~, Projects ~ W.D.E. Irwi
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GR&DC PROFESSIONAL STAFF <- , , - : > SPECIALIST RESOURCES '.:. Future Technologies:-- Dr. K.D. Kilburn .'~ .:.,::-.:!~ .. ::..~_~..~--.... /.. .... Special Projects: :,.~,.~-~,-~. H.G. Horsewell "o A.G. Barnes* Dr. P.C. Bevan Dr. G.A. Few "Dr. J.D. Green T.G. Mitchell Dr. P.S. Stewart Dr. T.W. Tolman A.N. Other .,,,; :,~. ... - .. PRODUCT"TECHNOLOGY MANAGER: ~!~:-...~<t~:~:~,i~ A.L. Heard Manager: .,4-~-:~:~,Dr. T. Hirji • ~:~"'~°,-~,-~,.~-~."~-- '~ ~':;~- E. Alty • ~:~,' .. "- -!~,'-. :;': ;-,,: ~ .... ' ..... " N. Bruce-Miller "~~:~#:y~L~ " ":: " D.E. Creighton ..... - " ur. C.C. Greig • Dr. C.R. Jenkins A.G. Stephenson .< Psychology** Manager: R.P. Ferris Dr. L. Miller Dr. L. Sumiga Sidestream Manager: W.D.E. Irwin SPECIALIST RESOURCES (see also above) International and Specialist- Committees Smoking issues Patents Dr. S.R. Evelyn Dr. R.E. Thornton K.J.H. MacL~an Planning P.H. Gannaway .,% .._.~ .:",.v ~ ~" ........ ,on return from secondment overseas. ,,~. **A significant proportion of staff time will be allocated to_research, in close , . ~ "~'~'~:: r :" association with Smoke Research (Work Area 02) and Smoker Behaviour (Work Area"(~ •, ~:~.: .... ...-. ~. :.. i ':!, ~,~.~ ... _~, ~,~
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6R&DC PROFESSIONAL STAFF (CONTD.) . . -..>,:,>.~-..~ ..... . ...... . . . . ..... ,~e.~,aa >- ,: ~,-,~ "~"' : SUPPORT PROCESS RESEARCH ~.o,,ee~,-~....~5.~,,:.,- SCIENTIFIC RESEARCH MANAGER: Dr. M.J. Hardwick .~-e RESEARCH MANAGER: Dr. R. Binns ANALYSIS & TEST METHOD DEVELOPMENT .=, . . -.- Group Leader: ... H.F.D. D~mond .... :' :"~ C.L. Proctor ':-#' , .... '", W.J. Roles Statistics -',- E.B. Wilkes ,Computin9 .i: D.B. Mullen .- ,. ---~- B.M. Watts " Hhrarv & "..~ " ~'- :' Information . Dr. F. Marsh • .; ° Flavour Manufacture :- J.F.K. McCreadie • .. .. " .._ • °-'• i
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Z !. D L g~O'l;OO&l;~ _.-. .. • .°
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i WORK AREA 01 BIOLOGICAL RESEARCH GROUP LEADER: G. SMITH f 80% I 01 PARAMETERS AFFECTING THE BIOLOGICAL ACT IV ITY OF SMOKE (PROJECT RIO) 60% [Ol(a) |Cigarette --|composition |and [construction .15% lOt(b) _ Activity of smoke components -02 5% lot(c) ) --|Smo k i n g EPattern I " 15% I DEVELOPMENTi OF SHORT TERM TESTS 10% TOTAL STAFF: 3 Graduates 14 Assistants EXTERNAL CONTRACTS: £91,000 (1984) FO2(a) IMutageni city -lof whole smoke Land vapour phase 5% 02(b) Enzyme induction model related to cancer ' I 5% I 04 CONSULTANTSi 03 HUMAN i STUDIES FO3(a) "I -|Smoking ano Lbodyweight 103(b) } --I Lung Ipermeabi I i ty o3(c) Development -- of athero- [sclerosis _[04 ( a ) ] IMutageni city [Prof. B- Bridges [04(b) _ --IHistopathology [Mr. D. Walker cn ~b c~

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