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Product Design

Subject: R&D Monthly Highlights

Date: 30 Sep 1991
Length: 12 pages
507795487-507795498
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Abstract

Consists of company-wide progress report on current research and development projects, focusing on status, significance, and next steps, along with responsible company research group. Includes sections on: Winston KS; Camel Lt. 83 Box; XB 2 mg Product; XA FFLT 85 NM Focus Groups; Mainstream smoke solanesol; Value tobacco usage; REST applications - Controlled tobacco solubles; Casting/extrusion processes; Paper technology; Cigarettes beetles; and Whitaker Park & Tobacco Processing Sensory Panels. Includes 8 page addendum listing and prioritizing projects not included in the report categorized by topic: brand; advanced technology products; biochemical/behavioral; materials development; process technology & development; technical support; and administrative, ag[ricultural] science, and avoca.

Fields

Notes

Operation/Project: Project AT, Project LF, Project XA, Project XDU, Project XD Brand: Winston Lt 83 CPB, BLS, Salem RH/RQ, Salem Plus, Camel QQ Smoke Constituent: Acetonitrile, alpha-Borneol Glucoside, Polyphenols, Carbonyls, Solanesol Named Organization: Nuway-Microflake Additive: Alginate

Author
DiMarco, Gabriel Robert, Ph.D. (RJR Senior VP R&D; CTR Board)
Senior Vice President of Research and Development at R.J. Reynolds; on Council for Tobacco Research (CTR) Board of Directors
Recipient
Dahne, Wolfgang D. (RJR International R&D VP 1991-92)
Senior Vice President of Research & Development for RJR Tobacco International Inc. in 1987 and Vice President of Research & Development for RJR Tobacco International Inc. 1991-1992. (Source: R. J. Reynolds Summary - RJR Liability Notebook)
Ford, Yancey W., Jr. (RJR Field Sales Sr. VP, 1988, Sales Exec. VP 1989+)
Yancey W. Ford, Jr. was Senior Vice President of Field Sales for RJR Sales Co. in 1988, was a Director for RJR Tobacco Co., Executive Vice President of Sales, and Executive Vice President & General Manager for RJR Sales Co. in 1989, and in 1990, 1992, and 1994 was Executive Vice President of Sales. (Source: R. J. Reynolds Summary - RJR Liability Notebook). Yancey W. Ford, Jr. worked for RJR Tobacco Co. as a Sales Rep. in 1962; Assistant Director of Sales Manager 1965; Administrative Assistant to Manager of Sales, Training & Development 1967; Director of Sales Manager 1968; Assistant Regulator of Sales Manager 1970; National Vending Manager 1972; Assistant Zone Sales Manager 1974; Zone Sales Manager 1974; Director of Sales Planning 1978; Director of S. Atlantic Sales Area 1979; Group Director of Sales Operations 1982; Vice President of Sales Operations 1983. (Source: RJR Who's Who NMLRP)
Iauco, David Nicholas (Senior VP of Marketing at RJR from 1989-2003)
David N. Iauco was Senior Vice President of Marketing for RJR Tobacco Development Co. 1988-1989, Senior Vice President of Marketing in 1992, 1994, and Senior Vice President of Worldwide Business Development in 1995. (Source: R. J. Reynolds Summary - RJR Liability Notebook). Senior vice president for marketing, R.J. Reynolds Tobacco Co. in 1994 (NYT 5/13/94. Iauco says that RJR had actually reached the market with a cigarette that carried less health risks than Premier; but the company was constrained in the claims it could make about the product (NYT 5/13/96). He was used as an expert in the Mississippi case.
Isbister, David K. (RJR VP of Tech, Leaf, Tobacco Processing)
Defense
*Johnston, J. W. (use Johnston, James Wesley)
Chairman & CEO
Juchatz, Wayne W. (RJR, Senior VP, Secretary and Counsel, 1993)
Wayne W. Juchatz served as Director in for RJR Tobacco Co. 1987, 1990-1995, Vice President in 1986, General Counsel & Secretary in 1986, 1988-1995, Senior Vice President & General Counsel for RJR Tobacco Development Company in 1987, Senior Vice President 1988-1994, and Executive Vice President in 1995. (Source: R. J. Reynolds Summary - RJR Liability Notebook). Wayne Juchatz was Assistant Secretary in 1984. (Source: RJR Who's Who NMLRP)
Myers, Grover M.
Defense
Schindler, Andrew J. (RJR, President and CEO (1994-present))
Andrew J. Schindler was President & Chief Operating Officer-USA of RJR. (N.M. Tobacco Companies Personnel List)
Hypothesis
Behavior Targeting
Cigarette's effect of enhancing/mitigating specific behaviors
Introduction of new/unconventional products
Research and development of novel nicotine delivery devices and experimental tobacco designs.
Sidestream constituent yields
Modification of selected sidestream smoke constituents in response to health concerns.
Smoke constituent testing
Development of methods for measurement of gas and particulate yields in mainstream and sidestream smoke.
Use of filters, paper, and ventilation
Modification of tobacco products through use of filters, paper, and ventilation, and measuring effects on dependence, behavior, and toxicity.
Use of tobacco processing/ blends
Modification of tobacco products through changes in tobacco processing and use of blends, and measuring effects on dependence, behavior, and toxicity.
Keyword
Cotinine
Brand Specifications
Consumer acceptability (Consumer preference)
Flavor/ Taste (Attribute measure)
Smoothness/Harshness (Attribute measure)
Smoke Constituent
Benzene
Nitrosamines (N-nitrosamines)
Toluene
Nicotine
Design Component
Reconstituted tobacco
Burley tobacco
G7 (RJR @reconstituted_tobacco)
Operation/Project
Project XC
Project XB
Named Organization
Kimberly-Clark Corp. (Specializes in the tobacco reconstitution process)
Specializes in the tobacco reconstitution process and in helping the tobacco companies control their nicotine
Ecusta (major cigarette paper supplier)
Occupational Safety and Health Administration (Held hearings in 1994 to ban smoking in workplaces)
OSHA opened hearings in September 1994 on a proposal that amounts to a virtual ban on smoking in every workplace in the nation
*Department of Health and Human Services
Brand
Camel (RJR)
CAMEL ULTRA LIGHTS 85
Camel Ultra Lights Box 80
Carlton (ATC)
Marlboro (PM)
Now (RJR)
NOW 85
Salem (RJR)
Sterling
Vantage (RJR)
Winston (RJR)
Winston 100
Winston 85
Winston Ultra Lights 85
Subject
Blends (Design)
Pharmacology (Effects)
Receptors (Effects)
secondhand smoke/health effects
Sensory Effects—Impact (Effects)
Sensory Effects—Taste (Effects)
Smoke Nicotine (Measures)
Smoothness/Harshness (Effects)
Test/Reverse Engineering (Testing)

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September 30, 1991 To: Mr. J. W. Johnston Subject: R&D Monthly Highlights WINSTON KS (Brands) Status: The WINSTON KS Impact Perceptions Test results indicate that current WINSTON KS is su erior to Marlboro KS among both prime prospect and franchise smoker groups. Significance: Among 21-49 year old Marlboro smokers (prime prospect), WKS scored superior to Marlboro on %70+ acceptance, purchase interest, strength, harshness (at ideal), tobacco taste, mildness, and burn rate (slower); Marlboro KS had no advantages versus current WKS. Among franchise, WKS also scored superior to Marlboro on %70+, mean thermometer, purchase interest measures, strength, bad aftertaste, and burn rate; disadvantages for WKS were draw (too easy) and smoothness (too smooth). An additional prototype, developed from early QD 'smoothness' learning, tested at parity to Marlboro among both smoker groups with advantages of ideal smoothness, slower burn rate but disadvantages of too little strength/tobacco taste. In-market perceptions of WKS were of a strong, harsh, not smooth or mild product (among both prime prospect and franchise smokers). However, upon receipt of identified product, acceptance ratings and attribute scores improved significantly. Sixty-two percent of the prime prospect smokers felt that WKS performed 'somewhat to much better' than expected; fifty-eight percent of the franchise felt the same. Next Steps: Continue internal developments to address pack aroma. Conduct further analyses using current WKS to examine the effect of APET versus polypropylene on headspace components over time. CAMEL Lt. 83 Box (Brands) Status: Preliminary results have been received from a consumer test (PGT) that examined four CAMEL Lt. 83 Box prototypes with prime prospect 18-24 yr. old competitive male smokers. Variables were: CarboWax filters, increased tobacco rod density, MTT flavor system, G7-25, and low stalk blend. Based on acceptance and attribute performance, the G7-25 prototype was identified as the best opportunity for improving CAMEL Lt. 83 Box. Compared to current CAMEL Lt. 83, this prototype had a superior mean thermometer score, strong parity (59-vs-54) 70+ score, and had significant key attribute advantages in smoothness, harshness, mildness, strength, and tobacco taste. Although this prototype remains inferior to Marlboro Lt. on acceptance scores and harshness, it achieved parity smoothness, mildness, strength and tobacco
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taste versus Marlboro Lt. Box. Efforts are underway to implement this improved product on CAMEL Lt. 83 Box and evaluate it for CAMEL Lt. 85 as quickly as possible. Significance: This is the first time that CAMEL Lt. 83 Box has obtained parity smoothness, mildness, strength and tobacco taste to Marlboro Lt. with a cork tipped product in blind PGT testing. The G7-25 prototype also greatly reduced the harshness deficiency of the current product versus Marlboro Lt. Next Steps: Evaluate the results of another consumer test mailed 9/23. The product is being tested blind and identified among competitive smokers and identified among franchise smokers. XB 2 mg Product: (Advanced Technology Products). Status: Results from an XB 2 mg "tar" PGT have been received. This test was conducted among 300 category 3 - 6 mg "tar" ULT non-menthol 85mm, 25+ male and female, RJR and competitive full-priced smokers (excluding NOW and Carlton). The 2x2 test design had 2 controls and 4 XB 85 mm products; XB used these technologies: . Filter: STT CAWeb . Blend: G7-1 with KDN (G7/KDN) G71 0 with heated extract and KDN (G7DAP/KDN) Products with CAWeb and/or G7DAP/KDN scored significantly higher in the %70+ measure than the NOW control or the product containing G7-1 with KDN and STT filter: NOW G7/KDN G7DAP/KDN G7/KDN G7DAP/KDN VULT STT STT CAWeb CAWeb %70+ 29.09 33.18 39.57 42.79 44.49 57.18 Significance: XB technologies show significant improvements over NOW 85 with 3 products superior to NOW for acceptance primarily due to strength, tobacco taste, and draw advantages. CAWeb had taste and aftertaste advantages, while STT had the advantage of more strength. Next steps: Investigate technologies to immediately address the disadvantage of draw seen in all four XB products. Continue product development on both a 1 mg and 2 mg product and further investigate opportunities in the marketplace for low T/N products. XB products, along with NOW concepts, will be consumer tested in mid-October. XA FFLT 85 NM Focus Groups (Advanced Technology Products) Status: WINSTON Futures focus groups were held in Albuquerque on 9/4 & 5/91. Three XA prototypes (having variables consisting of different flavor systems and blends) were evaluated on a one-cigarette basis by FF/FFLT 85mm and 100mm smokers. Prototypes made with the XA/XB flavor system (0.035%) performed exceptionally well. Favorable comments were received on both strength and taste. Prototypes made with the XA209 blend were also well received. Prototypes made with the CM117 flavor system did not perform well; these cigarettes were too harsh and stale. Next Steps: Prototypes using the XA/XB flavor system and the XA 209 blend will be made in the Pilot Plant and evaluated in the 11 /11 /91 FFLT CPGT. 2
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Mainstream Smoke Solanesol (Biochemical/Biobehavioral) Status: Mainstream smoke samples of the 50 leading U.S. cigarette brand styles (64% of total market) were analyzed for solanesol content as part of a study aimed at calculating "cigarette equivalent" exposure to ETS based on a particulate-phase tracer. Mainstream concentrations ranged from a high of 0.63 mg/cigt for CAMEL 70NF to 0.08 mg/cigt for Carlton 100. Sales-weighted average concentrations were: 0.46 mg/cigt for FF, 0.28 mg/cigt for FFLT, 0.16 mg/cigt for ULT, and 0.37 mg/cigt average overall. Significance: "Cigarette equivalent" exposure based on solanesol is expected to yield estimates significantly lower than the same calculation based on nicotine. These data will be used to argue that nicotine (and thus cotinine) overestimates ETS exposure. In addition, the exposure magnitude of smokers to solanesol is needed for upcoming experiments aimed at studying potential body burden and 'tar' uptake in smokers and the feasibility of using solanesol (or some metabolite) as an indicator of ETS exposure in nonsmokers. Value Tobacco Usage (Materials Development~, Status: Plans for "Value" tobacco usage were developed. Current and future Value product blends were adjusted to ensure total G7 usage for RJRT and RJRTI of between 112 and 115 MM lbs. G7 levels in generic and sub-generic products will be increased to approximately 33% and 40%, respectively. Significance: With increased levels of G7, plus maximization of offshore tobacco usage in the Value blends, the utility of flue-cured Stab and burley Pool Value tobaccos has been extended: Stab depletion - 2093; Pool depletion - 3Q93. Next Steps: Modify MSS CKPL blend to reflect needed grade changes, dependent on product quality, inventory constraints and business needs. All Value products will adopt the TB5 oriental blend 2Q92. REST Applications - Controlled Tobacco Solubles (Process Technology & Dev.) Status: High filling capacity tobacco, incorporating depleted solubles lamina and extracted burley stems containing lamina solubles, were evaluated against a G13-23 control at 15% inclusion in WINSTON Ultra prototypes. Internal and focus group sessions perceived the test materials to be at least equal to the control, with indications that smooth/ mild smoking character could be impacted positively. Significance: Opportunities in reducing leaf purchases or replacing current expanded tobaccos by using high filling value REST materials are evident. Process cost and quality benefits might also be realized. The ability to simultaneously perform other treatments, e.g. G7-25 processing, could enhance quality further. Next Steps: Formulate plans with Brands to further optimize prototypes within the current concept for Savings and ULT products. Casting/Extrusion Processes (Process Technology & Development) Status: Approximately 2000 pounds of cast sheet were produced from stemmery dust at Nuway-Microflake. In spite of the high sand variability and after slight formulation changes, all sheets were produced under the "pectin-release" format and conditions. Significance: The cost of Savings products can be reduced by replacing expensive Part II strip with cast sheet made from stemmery dust. At a projected cost of $0.86 per pound, the savings should be substantial. 3
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Next Steps: Complete all necessary evaluations associated with the introduction of a new blend component to include weight/firmness testing, aging studies, toxicological measurements, and primary processing assessments. Paper Technology (Process TechnoloQy & Development) Status: G7-25 has been implemented in all savings products as well as CAMEL Ultra Lights and CAMEL Light Box. Production capability exists at No. 603 and will be available at No. 90 in November. An Engineering study is underway for No. 92 Processing, with possible implementation in the second half of 1992. Significance: G7-25 reduces harshness and improves smoothness, making it an acceptable sheet for a large number of brand styles. Even though further improvements will be made, G7-25 has been developed to a stage where it is beneficial in many brands. Next Steps: Complete testing in other major brands. Complete process optimization and specification studies. Further enhance sensory characteristics through the work of the Rich Group. Cigarette Beetles (Admin/ Aca Science/ Avoca) Status: This summer, cigarette beetle outbreaks occurred in both storage and production facilities. A large number of control measures were implemented in storage, processing, and M&P areas. The massive infestation has now subsided. Significance: Cigarette beetle damage decreases the quality of the tobacco and can result in cigarettes containing beetles. Next Steps: Discontinue fumigations of RJRTI products and reduce monitoring and methoprene fogging frequencies to appropriate levels. Whitaker Park & Tobacco Processing Sensory Panels (Technical Support) Status: Employee acceptance panels are being established at WP and Tobacco Processing. A computerized directory has been developed for selecting participants based on brand and style. Contact personnel, responsible for scheduling and conducting tests, have been designated at each testing location. Significance: These employee acceptance panels are being established to address product developers' need for quick results and product acceptance measures. These panels will be used primarily for screening purposes, but will also be available for unique testing such as focus groups. Panels will be used initially for WINSTON Futures development. Next Steps: Conduct orientations on testing procedures for all participants by mid- October followed by methodology verification testing. G. R. Di Marco ~ C J Distribution: Mr. W. D. Dahne Mr. W. W. Juchatz Mr. Y. W. Ford, Jr. Mr. G. M. Myers Mr. D. N. lauco Mr. A. J. Schindler Mr. D. K. Isbister 4
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Addendum Because of space limitations, the vast majority of R&D projects do not get reported beyond the individual R&D group highlights. If anyone would like a status report for any "updated but not reported" project, please contact Harold Threatt (4040). For September, these are: Brands: . Brands Development - WINSTON 100 - WINSTON Lt 83 CPB - FFLT Development (Smoothness/ Harshness) - WINSTON Lt 83 Box - STERLING - BLS - Project LF - SALEM RH/RQ - SALEM PLUS - Project AT - G7-25 - CAMEL QQ - CAMEL Ultra Lights . Product Transition and Implementation - Blend Change for Sub-generic Brands - YSL Export Start-up Advanced Technology Products: (* Indicates Priority Items) . New Business Development - General: - Qualitative and Quantitative Headspace Analysis of Heat-Treated G-7 Extracts - Project LF Filters - Burn Rate Study - EVG Papers - Inner/Outer Wrap Reversal - Top-Dressing Evaluation - Inner Wrap Mill Trial (MTR 2260) - Machinability of Kimberly-Clark Inner Wrap P-3284-14 - Ecusta LSS Paper Trial , . - Extract Evaluation - Evaluation of Kimberly-Clark's Alginate-Treated LSS Outer Wrap - Evaluation of Alginate-Treated Outer Wrap from 8/91 Mill Trial - Pack Moisture Study - Test Product Production i
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. Project XA: - Aroma Precursors * - Blends - Filter Flavors - Vapor Flavor - G7/KDN Filter Segment - STT Filters * - XA FFLT 85 NM Focus Groups * - XA FFLT NM 100mm Consumer Testing - XA FFLT Menthol 100mm Consumer Testing - XA FFLT Menthol 100mm Bxtended Use Testing - XA Presentation to Dr. Bernard Wagner - XA Full Flavor Development - Qualification of XA Outer Wraps - Sidestream Smoke And Prototype Improvement Efforts -- Evaluation of the Effect of Extract Application to Reconstituted Sheet used as an Alternate Filler in the Blend -- Evaluation of Alginate Single-Wrap Prototypes * -- Ecusta Carbon Inner Wrap Exploratory . Project XB: - Nicotine Volatility/Sensory Response Research - Levulinic Acid Aging - Contract Research: Human Studies on the Effect of Acids on Nicotine Perception - STT Filters Stability Study * - XB 85mm - 6 mg Product - XB 100mm - 6 mg Product - XB 85mm - 2 mg PGT Test - XB 100mm - 2 mg Product * - XB Genetic Toxicology Evaluations - Other XB Blends * - XB Process . Project XC: - Carbon Filter - Effect of Paper Porosity - Carbon Filter - Phenol Removal - Carbon Filter - Uniformity - High Ventilation - Manganese Dioxide Catalyst - Flue-Cured "Tar" Composition - Burley "Tar" Composition Study . Project XDU: - Heat Source Development * - Heat Source Performance Measurement - Heat Source Flavor Development 11
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- Glass Development . Paper Development: - Insulator Paper - Laminate Sheet (Paper + Foil) * - Barrier Papers * - Sandwich Papers . Mouth-end Piece Development . * Substrate Development . Cigarette Ignition Propensity: * - External Issues - LIP Prototypes - Packing Density Study - Flow-Through Method . Operations Development: * - Project XA - Double-Wrap Maker - Project XB Support - G7 Materials with KDN Extract; Spray-Dried Tobacco Extracts - Project XC Wood Pulp Paper Filter Test; Carbon Paper Filter Test * - Project XDU - Paper Substrate * - Project XDU - Heat Source - Project XDU CA Filter Tests - Project XDU Tobacco Paper Filter Tests - Project XDU Mouth End Piece Tests - Project XDU Insulator Rod Tests - Project XDU Poly Filter Test 1097 - PT&D Support - G7 Dust Extract - Hand Fabrication Lab - Inventory Control . Asset Management Programs: * - Equipment * - Material Inventory Biochemical/Biobehavioral: (* Indicates Priority Items) Cellular/Molecular Biology Division - . Ames Testing - New Materials Development - Leaf Management - Growth/Improvement of Existing Business - Product Understanding -XA . Biological Activity Assessment of ETS - DNA Adduct Assay - Acute Inflammation - Cytogenetics m
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- Cell Proliferation - Red Blood Cell and Mononuclear Blood Cell Collection . Cytotoxicity Testing - Project XC . Method Validation - Acute Inflammation . Microbiological Services - Potassium Sorbate Study - Mold Counts - Sorbic Acid - Mold & Yeast Counts Pharmacology Research Division - . Literature Review - Smoking and Alzheimer's Disease . * Literature Update - Neuropharmacology Article . Nicotine Receptor Pharmacology - CONAR - Monograph - PB-PK Model for Nicotine - Nicotine Receptor Function - Neurotransmitter Release - Receptor Function . Nicotine Uptake and Metabolism - Development of Thermospray LC/MS Method - ELISA - Isolation of Cotinine Glucuronide from a Smoker's Urine - NMR of a Protected Nicotine Glucuronide - Seminar on Cotinine Glucuronide . Product Support - Skin Painting Studies . Pharmacology - Scientific Abstracts Biobehavioral Research Division - .* Anti-Tobacco Meeting - ASAM 4th Annual Conf. on Nicotine Dependence . Basic Sensory Research . Nicotine Research - Four-Cities Study - New HMSM - Nicotine RSM -- Blood Nicotine Study -- Puff Profile Analysis -- Smoking Replications -- Reports and Documentation - Support to Analytical Services . Product Understanding iv
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- Role of the Trigeminal Nerve in Odor Perception - Support to APT - Implementation of Radioimmunoassay (RIA) for Nicotine and Cotinine . Psychophysiology of Smoking - 1989 Smoking/EEG Study . Support to ETS - Response to OSHA's Draft RFI/ANPR . Scientific Affairs Division . Ingredients/Processes - Vantage Brand Family - - SALEM Brand family erimental Top Dressing - Litigation Support - Project XD - REST/Controlled Nicotine Process - Tobacco Additives HHS Report = - Flavor Approval - Solanesol Evaluation . Internal Domestic Status File . International Tobacco Additives - Indonesia . Manufacturing - Material Evaluation Program - Inks and Packaging . Material Safety Data Sheets . Occupational Health - DIET Process Nicotine Exposure - Sound Level Survey at Tobaccoville - Safety Glasses - Health and Safety Training - Confined Space Entry - Eyewash Stations and Showers - Freon 11 Sampling at Plant 63 - Job Safety Analysis - Hearing Van - Respiratory Protection at Tobaccoville - Respiratory Protection at Plant 200 - Varsol at Plant 200 - Propylene Oxide and N-Propyl Acetate at Plant 200 - Propylene Oxide and 1,4-dioxane at Plant 604 - Carbon Tetrachloride Survey at Plant 604 - Carbon Tetrachloride, Heptane, N-Propyl Acetate and Toluene at Plant 604 - Valspar Heat Seal Coating - Welding Fumes - Contaminated Soil Sample v
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. Planters LifeSavers' Quarterly Safety Meeting . Pesticides - Bulker MH Residues - Offshore Dealer Tobaccos - RJR Institutional Biosafety Committee (IBC) . Radiological Health - Radioactive Material Shipment - Radiological Health Safety Committee Meeting - Area Wipe Tests Survey - Radiation Safety Orientation at Whitaker Park - Health Physics Society Executive Council Meeting - VDT Survey - Radon Screen - Leak Tests - Hauni Gauge - Radium-226 Sealed Sources - Flow Gauge Area Survey - September Film Badges and Rings . Unknown Material in Oriental Tobacco Shipping Case Environmental Tobacco Smoke Division - . Collaborative Study for Polyphenols . Determination of Smoke Component Distribution . "Distance-from-Smoker" Study . ETS Anions . ETS Chamber Studies . ETS Literature Database . Fourier Transform Infrared Spectroscopy . Indoor Air Quality Studies - Analyses of RSP, Ultraviolet Particulate Matter, and Fluorescent Particulate Matter for TITUS Study - ASHRAE Ventilation Test - Plaza Building Indoor Air Quality Study - Smoking Lounge Study - Spouse Pairs ETS Study . Nitrosamine Analysis - Blend That Contains Burley Stem - BLS Cigarette Containing Burley Stems - Project XA - Menthol XA Product . Official ETS Nicotine Method . Primary Aromatic Amines . Product Support/Project XA . Project XA - Analysis of Nicotine,for Product Characterization Program . Sidestream Smoke Carbonyls vi

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