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Product Design

Vapor Phase Removal and Nicotine Augmentation with All Air Dilution Cigarettes

Date: 04 Apr 1977
Length: 15 pages
00778476-00889490 Exhibit 101
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youth 2920

Abstract

Study describing use of air dilution as an alternative to the addition of nicotine for low tar cigarettes with enhanced nicotine (as part of the nicotine augmentation project). Lists removal efficiencies for smoke constituents using an all air dilution cigarette with no cellulose acetate filter plug. Other findings include increase in nicotine to tar ratio and increase in smoke pH, indicating potential use for all air dilution cigarette for low gas phase delivery. However, at tar levels below 6 mg, difficulties in pressure drop and lighting occur.

Fields

Author
Skladanowski, M A
Hypothesis
Mainstream constituent yields
Modification of selected mainstream smoke constituents in response to health concerns.
Nicotine transport, transfer, and uptake
Design changes which alter nicotine delivery or effect how the product causes and maintains dependence, including transfer of nicotine from tobacco to smoke, and uptake into the body.
Use of filters, paper, and ventilation
Modification of tobacco products through use of filters, paper, and ventilation, and measuring effects on dependence, behavior, and toxicity.
Free Nicotine
Smoking psychology and behavior
Smoke Control
Keyword
Alkalinity (High pH, Basic)
Ciliatoxic
Free nicotine (Unprotonated or unionized nicotine)
Nicotine augmentation
Tar/Nicotine ratio (Nicotine/Tar Ratio or T/N ratio)
Vapor phase removal
Additive
Volatile acids
Ammonia
see also: Ammonium bicarbonate, Ammonium carbonate, Ammonium chloride, Ammonium hydroxide, Ammonium sulfide, Diammonium phosphate, and Urea
Smoke Constituent
Hydrogen cyanide (HCN)
Nicotine
Nicotine
Carbon monoxide
acrolein
Isoprene
2-Methyl Furan
Acetone
Acetonitrile
Toluene
Nitric oxides
Methyl ethyl ketone
Design Component
Filter ventilation (Filter vents, air vents)
Cellulose acetate filter (CA filter, Conventional filter)
Charcoal filter
Tipping paper
Filter ventilation (Filter vents, air vents)
Air dilution
Brand
Kent (Lorillard)
True (Lor)
Subject
Filters (Design)
Test/Smoke Constituents (Testing)
Smoke Nicotine (Measures)
Smoke pH (Measures)
T/N Ratios (Measures)
Tar (Measures)
Ventilation (Design)
Smoke Delivery/Transport (Measures)

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Page 11: 2920 Log in for more options!
Table 3. Results of the smoke analyses of sample AD70-8-True 85 a all air dilution cigarettes. #3 #9 #5 #7 Column Cap 9 holes 9 holes 8 holes none Plastic Section yes yes yes none Vent Holes 4 5 4 none Pressure Drop mm/cig 94.7~7.9 Nicotine mg/cig 0.77~.06 Corrected Part Mat mg/cig 7.8~.73 Puff Count 6.1~.14 % Nicotine Removal 31% % CPM Removal 57% Nicotine/CPM 0.i0 89.9~3.3 I07.5~7.5 63.1~4.5 0.69±.04 0~63±.0S l.~It, os 6.8+.27 6.3+.64 18.3+i.1 6.3+.25 6.2+.17 5.1+.15 38% 43% 63% 66% 0.10 0.i0 0.06 a. Diagram showing ADT0-8 True 85 (new True) m Z z 0 O
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Table 4. Results of smoke analysis of sample ADT0-40 Kent 85a all air dilution cigarette Pressure Drop mm/cig Dry Part Mat mg/cig Nicotine mg/cig Corrected Part Mat. mg/cig Puff Count Percent Nicotine Removal Percent CPM Ren~val N~cotine /CPM a. Diagram showing AD-70-40 Kent 85. 6 Air Vents 8 Air Vents Control 121.4 161.4 75.7 12.5 10.5 27.0 0.90 .73 1.32 11.6 9.7 25.7 9.4 9~0 7.9 32% 45% 54% 62% 0.078 0.075 0.051 0
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Table 5. Results of the smoke analyses of sample AD-70-8-True 85 (design #5} b and AD-70-8-All Puffed Blend a (design #5) (20) Sample Control Sample Control Column Cap 8 holes none 8 none Plastic Section yes none yes none Vent Holes 4 none 4 none Blend True 85 True 85 All Puffed All Puffed Weight mg/cig .877 Pressure Drop mm/cig 108 Dry Part Mat mg/cig 7.0 Nicotine mg/cig 0.63 Corrected Part Mat mg/cig 6.3 Puff Count 6.2 Nicotine/CPM 10.0 % CPM Removal 66 % Nicotine Removal 43 .680 .662 .462 63 112 68 19.4 7.5 19,8 1.11 0.80 1.33 18.3 6.7 18.4 5.1 4.7 3.8 6.1 11.9 7.2 64 40 a. 40% puffed flue cured plus 60% puffed burley treated with 2% (NH4)2HPO4• b. Diagram showing AD-70-8-design #5. m z r- Z z m
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REFERENCES: (1) (2) (3) (4) (5} (6) (7) {8) (9) (10) (ll) (13) (14) (15) (16) (17) (18) H. J. Minnemeyer, Nicotine Augmentation Project (NAP), Lorillard Memorandum, May 4, 1976. Gibson, James, et.al, U.S. Patent 3,878,850, April 22, 1975. J. D. Heck and N. S. Tong, "The Acute Toxicity of Nicotine Applied Dermally to Rats and Mice", Lorillard Report No. 969, Feb. 21, 1977. V. Norman, Beitr. zur Tabakforsch, 7(5):282, 1974. A. P. Miller, U.S. Patent No. 3,260,266, July 12, 1966. A. P. Miller, U.S. Patent No. 3,240,213, March 15, 1966. A. P. Miller, U.S. Patent No. 3,260,266, July 12, 1966. A. P. Miller, U. S. Patent No. 3,172,410, March 9, 1965. A. P. Miller, U. S. Patent No. 3,323,525, June 6, 1967. M O. Schur, U. S. Patent No. 2,988,088, Aug. I0, 1954. Sammel Atkins, U.S. Patent No. 3,058,476, Oct. 16, 1962. P. Bugge, U. S. Patent No. 3,057,360, Oct. 9, 1962. Elio Grassi, U. S. Patent NO. 3,394,708, July 30, 1968. Vello Norman, U. S. Patent No. 3,789,855, Feb. 15, 1974. Thomas Summers, U. S. Patent No. 3,695,274, Oct. 3, 1972. W. E. Routh, "Ammonia Treatment of Tobacco", Lorillard Research Report, Accession Number 968, Feb. 17, 1977. Winston Barnes, "Air Diluted, Red-Tipped True 85's", Lorillard Memorandum, Feb. 8, 1977. M. A. Skladanowski, "Effect of Air Dilution Filtration on Nicotine Delivery to the Mainstream Smoke", Lorillard Memorandum, April 23, 1976. (19) M. A. Skladanowski, "Air Dilution as a Filtration Technique to Increase Nicotine to Tar Ratios in the Mainstream Smoke of Cigarettes", Lorillard Memorandum, July 27, 1976. (20) M. A. Skladanowski, "Air Dilution Filtration of Cigarette ~ Smoke without a Cellulose Acetate Plug", Lorillard ~ Research Report, Accession Number 908, Nov. 4, 1976. ~ (21) Walter S. Ross, "Poison Gas in Your Cigarettes: Carbon ~ Monoxide", Reader's Digest, October, 1976, p. 114.
Page 15: 2920 Log in for more options!
(22) Walter S. Ross, "Poison Gases in your Cigarettes: Part II: Hydrogen Cyanide and Nitrogen Oxides", Reader's Digest, December, 1976, p. 92. (23) R. F. Davies, D. L. Topping and D. M. Turner, Atheroschlerosis, 24, 527-536, 1976. (24) Wynder and Hoffman, "Tobacco and Tobacco Smoke", Academi6 Press, New York, 1967. (25) M. A. Skladanowski, "Air Dilution Cigarette with Puffed Tobacco Blend," Lorillard Memorandum, December 15, 1976. O O

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