Product Design
Nicotine Neurochemistry
Abstract
Presentation on the general neurochemistry, neuropharmacology, receptor structure, regional receptor localization, and function of nicotine. Identifies nicotine as exogenous, effecting the Acetylcholine systems. Illustrates chemical transmission at a gap junction. Summarizes that nicotine receptors in the brain are regionally located, divisible into as yet unknown subtypes, which might have different functions. Suggests that nicotine might have different effects on different parts of the brain.
Fields
- Hypothesis
- Smoking psychology and behavior
- Neurobiology
- Keyword
- Brain activity
- Subject
- nicotine technology
Document Images
2023450271
Presentation
1. Introduction
2. General Neurochemistry
3. Neu ropharmalcology
4. Receptor Structum
5. Regional Receptor Localization
6. Function
7. Summary
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Presentation
1. Introduction
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3. General Neurochemistry
4. Neuropharmacology
5. Receptor Stru
cture
6. Regional Receptor Locallization
7. Function
8. Summary
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Introduction
Nicotine is~ exogenous
Nicotine effects Acetylcholline systems
Regional
localization
Multiple Receptors
Complex Interactions
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General Neurochernistry
Choline AcetWltransferase (CAT)
W Crude Mitochon~drial/Syna~ptosornal Fraction
Sotuble/P'articu
late
~ 66-70 kDa Km = 75G uM Choline
10 u M Acetyl-CoA
0 Highest Activity in Interpeduncular Nucleus
nhibited by Sulfhyd
ryl Reagents
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