Tobacco Documents Online

An Assesment of Twenty-Four Brands of Cigarette from the Swiss Market with Regard to the Retention of Particulate Matter and Nicotine in the Human Respiratory System

Abstract

Evaluates the retention of total particulate matter [TPM] and nicotine in a human subject and states the objective is to determine which design parameters minimize TPM deposition in the respiratory tract. Finds some humectants increase TPM retention, states ventilation decreases TPM retention and says additional research on the effects of humectants is necessary.

Fields

Notes

N.B.: Test was performed using a single human subject.

Hypothesis

Inhalation Profile

Are cigarettes designed to cater to individual inhalation profiles?

Low-yield cigarettes

Modification of low yield products to assure that adequate levels of nicotine delivery are maintained, and effects of yield changes on toxicity and dependence.

Measuring human intake

Development of scientifically valid procedures for measuring tar and nicotine levels that more accurately reflect human intake.

Smoking psychology and behavior

Use of tobacco processing/ blends

Modification of tobacco products through changes in tobacco processing and use of blends, and measuring effects on dependence, behavior, and toxicity.

Keyword

Brand differences

Human testing

Lower respiratory tract (Lungs, bronchial tubes)

Lung deposition (Respiratory deposition)

Nicotine delivery (Smoke nicotine or nicotine yield)

Per puff delivery

Per puff tar, per puff nicotine, and per puff CO

Puff parameters

Smoke particles

Total particulate matter (TPM or Tar)

Additive

glycerin

Propylene glycol

Smoke Constituent

Nicotine

Total particulate matter

Design Component

Humectant

Filter ventilation (Filter vents, air vents)

Named Organization

*British American Tobacco Company Limited BAT (See British-American Tobacco Co.)

Defense

Group Research and Development Center (Research center for BATco in Southampton, England)

Subject

Humectants (Additives to maintain moisture)

Test/Inhalation (Testing)

Smoke Constituents

Smoke Nicotine (Measures)

Tobacco Type (Design)

aerosol (technology)

Blends (Design)