Date: 10 Jun 1975
Length: 3 pages
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Length: 3 pages
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Compiles and summarizes the status of May, 1975 projects.
- Dunn, William L., Jr., Ph.D. (PM Smoker Psychology Principal Scientist 1970s-80s)Principal scientist at PM during the 1970s and 1980s, nicknamed the "Nicotine Kid." Supervised Victor DeNoble, Paul Mele, Carolyn Levy and others. Led "smoker psychology" programs for PM.
- Behavior TargetingCigarette's effect of enhancing/mitigating specific behaviors
- Inhalation ProfileAre cigarettes designed to cater to individual inhalation profiles?
- Measuring human smoking behaviorMeasuring the effects of changes in human smoking behavior on intake of nicotine and smoke constituents.
- Nicotine transport, transfer, and uptakeDesign changes which alter nicotine delivery or effect how the product causes and maintains dependence, including transfer of nicotine from tobacco to smoke, and uptake into the body.
- Smoke constituent testingDevelopment of methods for measurement of gas and particulate yields in mainstream and sidestream smoke.
- Smoking psychology and behavior
- Sensory targetingTargeting of smokers through changes in sensory characteristics
- Behavioral effects (Behavioral pharmacology)Addiction behavior, withdrawal, and measured nicotine effects
- Consumer acceptability (Consumer preference)
- Human testing
- Impact (Throat grab)
- Low delivery (Reduced delivery)
- Nicotine delivery (Smoke nicotine or nicotine yield)
- Per puff deliveryPer puff tar, per puff nicotine, and per puff CO
- Psychological effects (Experimental psychology)Perception patterns, inhalation patterns, and effect on delivery
- Puff pressure
- Puffing behavior (Human puff parameters)
- Smoker behavior (Human smoking behavior)Puff parameters, daily intake, etc.
- Smoke Constituent
- Total particulate matter
- Design Component
- Pressure drop (PD, Resistance to draw (RTD), Flow rate or Draft)
- Named Organization
- Product Opinion Lab (industry-funded)
- Marlboro (PM)
- Blends (Design)
- Effects—Smoking Behavior (Effects)
- Low Yield Cigarettes (Products)
- Menthol (Additives)
- nicotine technology
- Puff Parameters (Measures)
- Sensory Effects—Taste (Effects)
- T/N Ratios (Measures)
- Tar (Measures)
- Test/Consumer Preference (Testing)
- Test/Smoke Condensate (Testing)
- Test/Smoke Constituents (Testing)
- Test/Smoking Behavior (Testing)
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I I 1 1 4 1 I I I I I I I 1 w CHARGE NU'MBER': 1600 PROGRAM TITLE: Smoker Psycho1ogy PROJECT LEA'DER: W. L. Dunn, Jr. PERIOD COVERED: May 1-31, 1975 DATE OF REPORT: June 10, 1975 Project Title: Prodiuct-testing Methods Study Writteniby: W. L. Dunn and P. G. Martin 1) Methods in Field-testiing - A Study of Cigarettes and 2) The Infliuence of Tar Delivery and' RTD upon Subjective Ratilngs of Cigarettes. Report in preparation. Project Title: Cigarette Acceptability Monitoring Written by: F. J. Ryan, Cigarette samplies have beenimade and anal!yzed. The four lower cigarettes seem fine, the highest was too low. Rather than miistrust our ability toldesign a 20 mg cigarette, we have doubts about the analysiis and have requested it be resmoked. Projiect Title: Personallity and Stimulus Deprivation Written by: R'. L. Lieser and F. J. Ryan, Work on instrumentation coniti nu!es . A memo d'escri bi ng procedure in full was sent to Dr. Dunn. Project Title: Mixed Pack Study Written by: F. J. Ryan Bal l ots are blei ngi cod'ed and keypunchedi. POL report is due in mid-June. Project Title: Smoke Deprivation Written by: F. J. Ryan and R. L. Liieser Data gathering is complete ainid analysis is underway. Project Title: Puff Volume Work Written by: R. J. Ryan and R. L. Lieser Pilot subjects are being run to see whether smokers cani,, voluntarily adjust volumes to maintain constant tar per puff' across different delivery cigarettes.
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V 2 Projiect Title: Smoking and Verbal Learning, Written by: F. J. Ryan and R. L. Liieser A study is proposed to repil!icate Anderssoni's finding that smoking one nicotine containing cigarette interfered with performance improvement onia serial learning task but that after smoking a second cigarette the performance deficit was wipediout. No such effect was observed with nii,cotiine-free Bravos. We criticize this study because nicotilne dose was uncontrolled!, very light smokers were used, the design was incomplete, the observa- tioniperiiod wasni't long enough, etc. Our design will correct some of these flaws. This study, and one as yet to be determined, will be conducted in conjunction with the Personality and Depriva- tion investigation mentioned above, and subjiects will participate in all:three sequentially, instead of simultaneously as has often been done before. Project Titlie: Smokiing and Work Rate Written by: B. W. Jones A technical report has been completed. Project Titlie: The Effect of Smoking on Risk-taki1ng in a Simu ate Driyinig Task Written by: B. W. Jones Mood and personality data have beenianalyzed and a technica] report is being written. Project Title: Menthol Cigarette Preferences of Blacks Written by: P. G. Martin and B. W. Jones A technical report is being written. Projiect Title: The Inf1uence of Nicotine on Aggression in Bett& Fish Written by: P. G. Martin and B. W. Jones Two series of tests have been run in what has been referredl to as the "toxicity study" part of this investi,gati,on. It has beeni determined that the LC (Lethial Concentration) is greater than 10 ppm solution of disi0illed nicotine base at 27°C ±10and less than or eq,ual to 100 ppm. Solutions of 1 ppm and .5 ppm both appeared to result in avoidance of display to a mirror stimulus and main- tenance of normal air gulping, and swim pattern. Incholosing the two levels of nicotine to:be used in the effects study, it is important that the decrease in aggressive behavior be accompanied by observations that other behavior have remained normaT. Another series will be run with 1.0, 01.5, 0.1, and 0.05 ppm solutions before deciding which solutions will be used in the effects study.
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1 3 1 I I I 1 1 I I I I Project Tiitle: Low Delivery Cigarettes - The Influence of Delivery Ilnformation on Suibjective Evaluations (II) Written by: P. G. Martin an T B. W1. Jones Cigarettes have beenimai1ed out to a NatiionaI POL panel and many of the ballots have been returned. Project Title: A' LowiDelivery Cigarette with Impiact and Flavor Wriitten by: B. W. Jones and P. G. Martin This is the first study in the 5-6 mg tar delivery program being carried out in collaboration with Paul Gauvin, Barbro Goodman, and Willie Houck. The purpose-is to evaluate the relative influences of blend (Standard Marlboro blend vs. 50% burley blien&), burley spray (100% vs. 50%), and filter system (cellulose acetate filter vs. papier/celluil!ose acetate filter) on smoke impact and acceptabil.ity of cigarettes inithe 5 to 6 mg tar range. The eight experimental cigarettes and a Marlboro control shou]id go out shortly to 400 RP'3 smokers. Project Title: Smoking and Aggression Written by: B. W. Jones The simulated driving task used in the rilsk-taking study has been modified so that a college student may receive inaccurate feedback regard1ing his performance on the task. It is expected that a stud!ent who is being paid~for successful passing will respond aggressively if his successful passes are incorrectly recorded as crashes. There will be 30 subjects tested in each of the three smoking conditions (nonsmoker, smoker-deprived and smoker). AN subjiects wi l l have a 10-mi niute practice session before begi nniiing two 20-minlute trials. The first trial will be with accurate feedback so that baseline measurements may be obtained before_ inaccurate feedback is introduced. The smoker-deprived grouip wil'l be given a third trial with inaccurate fe'edba:ck. The group will be divided, with half of the subjects remaininigideprived and the other half being permitted to smoke. Subjects will be observed throulgh a one-way miirror, verbal behavior will be codedi, and the force with which they push the response buttons will be recorded. Equipment is on order for modificationis in the response buttons. College student pi,lot subjects will soon be brought in so that observational techniques can be perfected. N, j h _ . 1 4 /~~ Ca J