Product Design
Nicotinic Acid
Fields
- Author
- P, HB <PARMELE, HB>
- Recipient
- RIEFNER, A
- Named Organization
- UNIV OF WI
- Subject
- acids (additives)
- nicotine technology
- Brand
- Old Gold (LOR)
Document Images
P R E C I S I O N- T"DE wARK M I-C R O S T A T uG, u. i P-T OF+ M 1 C R O F I L
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1 2'
Oeteber i. 19i1
I
Mr. A. Riefner. BeoretatT
Co.aittet on 1lamtaeture
t. [orillard Ooaparp
~ i.. Torlc. f. T.
p.ar Sirs 'enbjeete lieotinio Aeil
d
1tef.rring to the .ubseot of niootinio seid, or the anti-pe11a6Ta
titaain, in oigaretts .agb, paiit us to state that M have heard ilras the
Qaiverdtr of risoonsin. snd arr r1esaPd to report t1+at they hav. Bonfirmed
enr findinaa in every respect. In other rords, in an apu.ous solution of tAa
swty froa ten ordinary Old 9o1ds thcr find .e uilligraa of niootinio aai.,
.fhil+s in a sinilar solution of the enok+ Srom ten enrirl»d oij;aretts thq
find 12.5 nillifrvu of the vitasdn in qasstlon. Theee fiC.aw oan be b+tb.r
appreoiatmd, if we repw4 that 10 to 16 ailligsas of niootinie said are t!e
8aiy requireaeate of an avaragp san.
Ia view of the above and t.ls data subnitted by aw.elvee in pr..ieae
earnespaadenoe, we feel oonfidoat in olaiains that the amoos fTw ordinart
Old Oolds oorrtains a tr+aoe of the aotirpellagra viter.in. Rathersroreo tLe
sawnt of t1e latter oen be GreatlT increased by addins nlootinie aeid to the
tobaeoo during the oourse of its nanut>,oture. In addition, we have previously
shown that a good proportion of the vitamin is absorbed by tfe saliva in a
moolesr's nouth, and subepuant.]y sstillorsd.
Me belie.o that tho abo.e stateoexts oor2plotely cover tle stcrT in
*estlon, nnd, in our opinion, thero is nothinG rore to be told. In other
.ords, w feel sure thnt niootinio aoid h_ae no direct soothing effect an
lrratated reioow maobranees, nor .i11 its pr.senoe in oi;,arette suob Lavn
ary appfeoiabls neuttalisirti; effect an the nbseotiornble aaaozila or tar alo
ezistlnp in the srwla. 'fheoe are t+ie ideas broudht rortfi by Yr. lseet, tut it
is our fYeerk opiai~n that thoy ere tasrorthy of atQ ezhau.tive invatlnatlon.
In other wordr, we feel that there cro other thinrs wore .ertlp of our effbrte
than the aba... .

ROLL Np.
l
c
Mr. A Riellset. 6aerehrr
Co4.ittae on 1Maut1«twe 4. Oetob.r i. 1941
1Ie should atata that the anriohad eifyrettaa aiotioeel in para6rayY
10. 1 wre esda by addinC a ona peroent applioatioa of aiootinia soid to the
tobaeoo ewployed. This additi.oa ereatos anoufh .itwtia in the ssoloa to baw
real potential therapentie effeota. So*..er, it 1a too nuoh to ba praotioal ft460
the standpoint of oost au w11 aa the supply of niootinie asid Awilable for we.
lhus, w.ovld probably aeed to be aatistYad with a.OQK additiea. This .aild
oa],y doubla ti* quantity of aiaotiaie aeid ortdiaarily pr.a.nts but would aoab]
ar aEants to adv.rti.a that "soorthing aw had been addaC". In brief& ye+ oaa
readily appfroiata that eipLretto smldn6 ean hardly be t+ada an effieieart q
of obtaining on.fa oo.plete daily supply of the aati-pellagrs .itaain. Ho.e.rsrg
it does offar a possibla subjeot for adwrtisinC saterials prot'idiny the latter
eaa "dresaed up" in an attraoti.e sna.r.
In olosinE w belie.* t?at it ><ight be a Ccod idea to patent the
addition o.' aiootinie aoid to tobaooo, partieularly if our ad.ertimin6 people
have ar.a the rsoteat Idea of nainR the aaterial for future oolq. Ifs after
the above ooor.eats, they baid* that the subjeet att.r is of ea valua,.thsa
we believe that we nir;ht be qi..n perniasion to publish our ftadinas, in order
~
. .
to blook a patopt by sos future party.
wu are vonderist; if you would think it ad+iL.ble to study oth.er
poaaible .itarflns in cigarette wiobs, so tiat our advertieir4; people wl,,ht
nentiially be able to speak of .itanins in the plural instead of sint,ular.
We will be intereated in reeei.in6 your ooaeat and arw deoisions ie
the metter .4.io`, yni Aqg tender. Plathernore, we will be fjad to study any aa6lea
ef the probloa ahSdt you artiy oara to su Ceat.
~
i
~ Very truly yourss
I
Chaad at
IQi*'LY.TOIrti 8RtW[
T.1M11JI1tU CCiYRY!
.
1
j HR7
