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D1076 1,3 ~~x~c ~BLZS eam c.GE IN RELATION TO PULMONARY I CHANGES: RUPTURE OF ALVEOLAR SEPTUMS, FIBROSIS AND THICKENING OF WALLS OF SMALL ARTERIES AND TERIOLES Eng J Med 269(20):1045-1054, 1963 '~UERBACH, 0./STOUT, A. P., HAMMOND, E. C., GARFINKLE, L./JOHNSON, H., WALKER, L. J. Lung specimens obtained from 1,592 consecutive patient autopsies were compared on the basis of smoking history for histologic evidence of fibrosis, rupture of alveolar septa, and thicken- ing of small arteries and arterioles. All of these changes were found to be greater in smokers than in matched non-smokers, and greater in heavy smokers than in light smokers. Racial and occupational factors did not appear to be significant. . NEW YORK MED COLL, NY, VA HOSP, EAST ORANGE, NJ/ VA HOSP, EAST ORANGE, NJ, AMER CANCER SOCIETY, NEW YORK, NY Autopsy study, Male-female data, Lung histology, Ten thousand, Alveolar fibrosis, Lung arteriosclerosis, Lung arteriolosclerosis, Alveolar rupture, Cigarette smoking, Smoking habits/Occupational factors, Race factors, Negro data, Exsmokers, Pipe smoking, Cigar smoking, Age factors, Smoking amount, Death causes, Lung cancer, Lung fibrosis, Lung hysema, Cor pulmonale, Bronchus histology// residence, East Orange NJ residence, English 3anguage, Grantor Amer Cancer Soc,-Coal miners, Asbestos workers, Chemical workers, White-collar workers, Factory workers, Laborers, Blue collar workers, Firemen, Gas station attendants, Bus drivers, Hot-metal workers