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PHILIP MORRIS U.S.A. RESEARCH CENTER, RICHMOND, VIRGINIA 23261-6583 RICHARD A. CARCHMAN, PHD VICE PRESIDENT SCIENTIFIC AFFAIRS James E. Enstrom, Ph.D., M.P.H. School of Public Health University of California 10833 Le Conte Avenue Los Angeles, CA 90095-1772 January 30, 1998 P.O. Box 26583 (804) 274-5794 Fex: (804) 274-3982 Reference: Principal Investigator James E. Enstrom, Ph.D., M.P.H. Dear _ Grant Title: "Relationship of Low Levels of Active Smoking to Mortality" 12--- . Philip Morris is pleased to enclose the second installment in the amount of $75,000 for a grant totaling $150,000 which was presented to you in support of your proposal entitled: "Relationship of Low Levels of Active Smoking to Mortality". The granting period is for two years. This installment is for the second year, 1998. We desire to fund quality scientific research and to promote the independent investigation of the issues described in the proposal. We request that we be kept informed of the progress of the research via periodic progress reports and by an annual presentation of the research findings to the Philip Morris Research and Development Community. Most importantly, we request that the results of the completed studies be published in peer-reviewed journals. Please keep me informed of the progress of your research. If the research contemplated by the proposal is completed and the total funds requested for this grant have not been expended, we expect a refund of the appropriate amount. We wish you the best of luck in your work. Additionally, we look forward to the results of the proposed studies. Very truly yours. Richard A. Carchman, Ph.D. Vice President, Scientific Affairs Enclosure cc: Dr. C. Ellis Dr. G. Nixon