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Philip Morris

Predicting Rodent Carcinogenicity From Mutagenic Potency Measured in the Ames Salmonella Assay

Date: 19970000/P
Length: 11 pages
2063633488-2063633498
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Fields

Author
Fetterman, B.A.
Kim, B.S.
Margolin, B.H.
Schildcrout, J.S.
Smith, M.G.
Wagner, S.M.
Zeiger, E.
Type
PSCI, PUBLICATION SCIENTIFIC
BIBL, BIBLIOGRAPHY
Area
CARCHMAN,RICHARD/OFFICE
Litigation
Iwoh/Produced
Characteristic
EXTR, EXTRA
MARG, MARGINALIA
Site
R530
Named Organization
Univ of Ca
Korea Research Foundation
Niehs, National Institute of Environmental Health Services/Sciences
Unc Ch
Univ of NC
Author (Organization)
Environmental Toxicology Program
Niehs, National Institute of Environmental Health Services/Sciences
Univ of NC
Wiley Liss
Yonsei Univ
Named Person
Bernstein, L.
Gold, L.
Kim, B.S.
Margolin, B.H.
Tindall, K.R.
Master ID
2063633486/4072
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07 Jun 1999

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Page 11: 2063633498 Log in for more options!
322 Fetterman et al. ity assays: An evaluation of 114 chemicals studied by the N~- tional Toxicology Program. J Am Stat Assoc 85:964-971. Hatch FT, Knize MG, Moore DH II, Felton JS (1992): Quantitative correlation of mutagenic and carcinogenic potencies for betero- cyclic amines from cooked foods and additional aromatic amines. Murat Res 271:269-287. Margolin BH, Kaplan N, Zeiger E (1981): Statistical analysis of the Ames Salmonella/microsome test. Proc Nat[ Acad Sci USA 78:3779 -3783. Margolin BH, Kim BS, Risko KJ (1989): The Ames Salmonella~micro- some mutagenicity assay: Issues of inference and validation. J Am Stat Assoc 84:651-661. Margolin .BH, Kim BS, Smith MG, Fetterman BA, Piegorsch WW, Zeiger E (1994): Some comments on potency measures in muta- genicity research. Environ Health Perspect 102(Suppt 1):91-94. Margolin BH, Risko ICI (1988): The statistical analysis of in vivo geno- toxicity data: Case studies of the rat hepatocyte UDS and mouse bone marrow micronucleus assays. In Ashby J, de Serres FJ. Shelby MD, Margolin BH, Ishidate M Jr, Becking, GC (eds): "Evaluation of Short-Term Tests for Carcinogens: Report of the International Programme on Chemical Safety's Collaborative Study on In Vivo Assays." Cambridge University Press, pp 1.31 - 1.42. McCann J, Choi E, Yamasaki E, Ames BN ( 1975): Detection of carcino- gens as mutagens in Salmonella microsome test: Assay of 300 chemicals. Proe Natl Acad Sci USA 72:5135-5139. McCann J, Gold LS, Horn L, McGill R, Graedel TE, Kaldor J (1988): Statistical analysis of Salmonella test data and comparison to results of animal cancer tests. Murat Res 205:183-195. Meselson M, Russell K (1977): Comparisons of carcinogenic and muta- genie potency. In Hiatt HH, Watson JD, Winsten JA (eds): "'Ori- gins of Human Cancer. Book C: Human Risk Assessment." Cold Spring Harbor, NY: Cold Spring Harbor Press, pp 1473-1481. Parodi S, Taningher M, Romano P, Grilli S, Santi L (1990): Mutagenic and carcinogenic potency indices and their correlation. Teratogen Carcinogen Mutagenen 10:177-197. Piegorsch WW, Hoel DG (19881: Exploring relationships between mum- genie and carcinogenic potencies. Mutat Res 196:161 - 175. Purchase IFH, Longstaff E, Ashby J, Styles JA, Anderson D, Lefevre PA, Westwood FR (I 976~: Evaluation of six short term tests for detecting organic chemical carcinogens and recommendations for their use. Nature 264:624-627. Sugimura T, Sato S, Nagao M. Yahagi T, Matsushima T, Seino Y, Takeuchi M, Kawachi T t 1976): Overlapping of carcinogens and mutagens. In Magee. PN, Takayama S, Sugimura, T, Matsu- shima, T (eds): "Fundamentals of Cancer Prevention." Balti- more: University Park Press, pp 191-215. Tennant RW, Margolin BH. Shelby MD, Zeiger E, Haseman JK, Spal- ding J, Caspary W, Resnick M, Stasiewicz S, Anderson B, Minor R (1987): Prediction of chemical carcinogenicity in rodents from in vitro genetic toxicit), assays. Science 236:933-941. Zeiger E (1987): Carcinogenicity of mutagens: Predictive capability of the Salmonella mutagenesis assay for rodent carcinogenicity. Cancer Res 47:1287-1296. Zeiger E, Haseman JK, Shelby MD, Margolin BH, Tennant RW ( t990): Evaluation of four in ~itro genetic toxicity tests for predicting rodent carcinogenicity: Confirmation of earlier results with 41 additional chemicals. Environ Mol Mutagen 16(Suppl 18): 1 - 14. Zeiger E, Risko KJ, Margolin BH (1985): Strategies to reduce the cost of mutagenicity screening with the Salmonella assay. Environ Mutagen 7:901-911. Zeiger E, Tennant RW (1986): Mutagenesis, clastogenesis, carcinogene- sis: Expectations, correlations, and relations. In Ramel C, Lam- bert B, Magnusson J (eds): "Genetic Toxicology of Environmen- tal Chemicals. Part B: Genetic Effects and Applied Mutagene- sis." New York: Wile.~. pp 75-84. Accepted K. R. Tindall

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