Tobacco Documents Online

17/10 '96 13:42 FAX 41 38 32 77 76 S&T Neuchatel "> CARCHMAN R _ PM Q004/009 ~ UNIVERSITA' DEGLI STUDI Df MQDE6NA DIPARTIMENTO D[ SCIENZE SIQMEDtCHE Sezione di Farmacologia . l6 41100 Modena, ? 'e7 via Carnvi. 287 . Tal. (059) 36_4Z4'r Sir, I have been working for many years in the field of neurclendocrine and behavioral pharmacology, including behavioral toxicology and teratology, with interesting results (a lisc of a few representative references is appended) _ Some time ago T studied the iafluence of prenatal exposure to cigarette smoke on the offspring of rats, and found that the rate of avoidance acquisition was -significantty betEer in the offspring of dams exposed to cigarette smoke than in controls (ltiteuroUehav. Toxicol. Teratol. 4,545-548;1982). More recently. I demonstrated that nicotine, intravenously injected, is extcemely porenr and effective ut reversing a condition of severe hemorrhagic shock in rats (Naunyn-Schmiedeberg's, Aseh_ Pharmacol_ 343,4?7-d.30:19'91). At present, I am trying to start a research pro;ram concerning the effect of r.ricotinc on learnina and memory, sexual behavior, behavior in depression-generating models, and sensory-motor performance of aging rats, because several neurobiochernical data would suggest beneficial effects of nicotine in these conditions. But I can't find any financial support from Public organisuas for such a research. So, T arn asking whether it might he possible to submit a detailed research project for a grant. 1 look forward to receive a reply to this letter, and I thank you very muchh for your actcntion_ My best regards. Sincerely_ zfl0 ~ -UOs S-DIQd 6Zt96_9 9 6CiQ, lC:tr 96. 60/0C