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R: REDACTED MATERIAL Larrv R. Glass, Ph.D.. M.P.H. REDACTED SUMMARY OF QUALIFICATIONS: • Experience in domestic and international regulatory toxicology and health issues • Career reflects progressively increasing levels of responsibility in areas of regulatory toxicology, product safety, environmental quality, and occupational health • Well-defined personal and professional standards and ethics; career reflects hard work, loyalty, and professional competence • Doctoral education in Toxicology and Risk Assessment. Post-graduate experience in analysis and interpretation of complex data-sets PROFESSIONAL EXPERIENCE 1 994-present Product Stewardship Scientist Occidental Chemical Company Niagara Falls, New York Develop strategy for product assessment, including the assessment of the potential hazards and development of risk management options. Serve as contract officer for conduct of product testing at outside facilities-review protocol, monitor study, interpret results, ensure timely communication of health research results of testing to businesses. Represent the company on committees at trade associations, regulatory hearings, inter-industry scientific committees, panels, and task forces.

Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 2 1990-1994 Manager, Health and Environmental Sciences The Carborundum Company Niagara Falls, New York Managed company-wide health sciences programs to minimize potential harm arising from the manufacture, distribution, sale, or use of company products. Managed company-wide compliance with HAZCOM, TSCA, Canadian Chemical Control Act, Hazardous Materials Transportation Act, and other pertinent regulations. Participated in the strategic planning and management of a worldwide Health and Regulatory Compliance Program (Product Stewardship Program) for Refractory Ceramic Fiber. Represented strategic company interests internationally in scientific forums, regulatory hearings, inter-industry scientific committees, trade organizations, interactions with customers, panels, and task forces. Participated in the management and oversight of multidisciplinary health effects research programs. 1989-90 Toxicologist, USEPA Environmental Criteria Assessment Office (ECAO) Cincinnati, Ohio Coordinated risk assessments of environmental contaminants as directed by CERCLA, SARA, RCRA, and other relevant statutes Reviewed quality of toxicologic and environmental studies for incorporation into risk assessments. Reviewed risk assessments to ensure their technical accuracy.

Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 3 Supervised the calculation of RQ's, RfD's, unit risks, and other determinations pertinent to the application of toxicologic and epidemiologic data. Managed the preparation and review of technical reports 1988-89 Postdoctoral Fellow Appointment to U.S. Department of Energy Postgraduate Research Program Oak Ridge, TN Toxicologist for a multidisciplinary team (expertise included epidemiology, ecology, statistics, mathematics, and health physics). Research efforts focused on the development of methods to evaluate the potential for adverse health consequences following "low-level exposures" to environmental agents. 1986-88 Joint Appointment: Visiting Scientist Oak Ridge National Laboratory (Health Effects and Epidemiology Group) Faculty Associate The University of Texas at Houston, School of Public Health (Epidemiologic Research Unit) Houston, TX Responsibilities same as the previous position.

Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 4 1986 Visiting Faculty University of Utah, Rocky Mountain Center for Occupational and Environmental Health Salt Lake City, UT Participated in the development and teaching of a "short course" on environmental epidemiology, toxicology, and risk assessment. 1984 University of Texas Health Science Center, Office of Environmental Health Houston, TX 982-83 Developed database to inventory hazardous materials on the campus. Project ensured compliance with "Right-to-Know" legislation. Senior Research Assistant 978-79 University of Texas School of Public Health Houston, TX Participated in the design and implementation of a research project to assess the in vivo and in vitro toxicity of formaldehyde. Chemist Philadelphia Electric Company/United Engineers Philadelphia, PA Responsible for chemical analysis of flu-gas to ensure compliance with Clean Air Act. ~ c~

Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 5 1977-78 Research Technician Albert Einstein Hospital Philadelphia, PA Participated in a research effort to develop a non-invasive method for the detection of thromboemboli. EDUCATION 1984-88 Ph.D., Toxicology/Risk Assessment. The University of Texas Health Science Center at Houston, School of Public Health (minors: Epidemiology and Statistics), Houston, TX. 1981-84 M.P.H., Occupational Health. The University of Texas Health Science Center at Houston, School of Public Health (minor: Industrial Hygiene), Houston, TX. 1979-81 Graduate Program in Pharmacology. Wayne State University, College of Pharmacy and Allied Health Professions, Detroit, MI. 1972-76 B.S., Biology (minor: Chemistry). George Washington University, Washington, DC. APPOINTMENTS/AWARDS 1991 Corporate Merit Award for Outstanding Contributions in Health, Safety and Environment 1990 Sustained Superior Performance Award, Office of Health and Environmental Assessment, Environmental ProtectionAgency Z\D 1987-89 Postdoctoral Fellowship, U.S. Department of Energy <= ~ Postgraduate Research Participation Program administered by c~ Oak Ridge Associated Universities '~ c,P 00 0 ~ 0

R: REDACTED MATERIAL Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 6 1982-85 NIOSH Scholarship for Study of Occupationally Induced Disease, The University of Texas School of Public Health 1981-82 Graduate Research Assistantship, The University of Texas Graduate School of Biomedical Sciences, Houston, TX 1980-81 Graduate Research Assistantship, Wayne State University, Detroit, MI REFERENCES Available upon request. REDACTED COMMITTEE PARTICIPATION Chemical Industry Institute of Toxicology • Member Representative Chemical Manufacturers Association (1994) • Dioxin Work Group • Endocrine Effects Work Group/Coalition 0 ~ Chemical Industry Institute of Toxicology (1994) a~ ~ cP • Technology Advisory Panel (TAP) on Fibers Research Program 00 0 ~ ~

Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 7 European Ceramic Fiber Industry Association (ECFIA) (1 993-present) • Industry Technical Sub-Committee on Regulation Refractory Ceramic Fiber Coalition (RCFC) (1 992-present) • Proposition 65 Task Force • Medical/Scientific Committee Thermal Insulation Manufacturers Association (TIMA) (1990-1992) • Toxicology Committee ® Medicai/Scientific Committee RESEARCH PROJECTS Longitudinal Respiratory Health Study of Employees in the Refractory Ceramic Fiber Industry: Five-Year Continuation Study of Pulmonary Morbidity and Mortality (1994-present) Role: Project management, oversight, and reporting of results Principal Investigator: James Lockey, M.D., University of Cincinnati Proposed Budget: $2,100,000 Sub-chronic Inhalation Studies of Respirable Man-Made Vitreous Fibers in Rats (1993-present) Role: Study design, project management and oversight, and reporting of results Principal Investigator: Research and Consulting Company (RCC), AG, Geneva, Switzerland. Cost: $500,000

Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 8 Pulmonary Surveillance Study of Workers Exposed to Refractory Ceramic Fibers (RCF) (1990-1993) Role: Project management, oversight, and reporting of results Principal Investigator: James Lockey, M.D., University of Cincinnati Cost: $750,000 Epidemiology Study of Workers Exposed to Refractory Ceramic Fibers (RCF) (1990-1993) Role: Project management, oversight, and reporting of results Principal Investigator: James Lockey, M.D., University of Cincinnati Cost: $2,500,000 Nested Case-Control Study of Workers Exposed to Refractory Ceramic Fibers (RCF) (1992-1993) Role: Project management, oversight, and reporting results Principal Investigator: James Lockey, M.D., University of Cincinnati Cost: $175,000 Lifetime Inhalation Studies of Refractory Ceramic Fibers (RCF) in Rats and Hamsters (1990-1993) Role: Interpretation and results reporting, project management and oversight Principal Investigator: Research and Consulting Company (RCC), AG, Geneva, Switzerland Cost: $7,400,000

Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 9 Lifetime Multiple Dose Inhalation Study of RCF in the Rat (1990-1993) Role: Interpretation and results reporting, project management and oversight Principal Investigator: Research and Consulting (RCC), AG, Geneva, Switzerland Cost: $2,500,000 Computer Modeling and Assessment of the Deposition, Clearance, and Retention of Refractory Ceramic Fibers (RCF) in the Lungs of Rats and Hamsters (1992-present) Role: Project management and oversight Principal Investigator: M.J. Utell, M.D., University of Rochester Cost: $80,000 Worksite and Job Task Exposure in Humans Exposed to Refractory Ceramic Fibers (RCF) (1990-1992) Role: Project oversight Principal Investigator: Morton Corn, Ph.D., Johns Hopkins University Cost: $2,500,000 RESEARCH PUBLICATIONS Yu, C. P., L. Zhang, B. Oberdoerster, R. W. Mast, L. R. Glass, and M. J. Utell (1993). Deposition modeling of refractory ceramic fibers in the rat lung. Journal of Aerosol Science. In press. Yu, C. P., L. Zhang, G. Oberdoerster, R. W. Mast, L. R. Glass, and M. J. Utelf (1993). Clearance of refractory ceramic fibers (RCF) from the rat lung: Development of a model. Environmental Research. In press.

Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 1 0 Yu, C. P., J. Ding, L. Zhang, G. Oberdoerster, R. W. Mast, L. R. Glass, and M. J. Utell (1993). Deposition and clearance modeling of inhaled kaolin refractory ceramic fibers (RCF) in hamsters-comparison with rat's results. Submitted for publication. Mast, R. W., E. E. McConnell, R. Anderson, J. Chevalier, P. Kotin, D. M. Bernstein, P. Thevenaz, L. R. Glass, W. C. Miller, and T. W. Hesterberg (1993). Studies on the chronic toxicity (inhalation) of four types of refractory ceramic fibers (RCFs) in male fischer 344 rats. Submitted for publication. McConnell, E. E., R. W. Mast, T. W. Hesterberg, J. Chevalier, P. Kotin, D. M. Bernstein, P. Thevenaz, L. R. Glass, and R. Anderson (1993). Chronic inhalation toxicity of a kaolin based refractory ceramic fiber (RCF) in syrian golden hamsters. Submitted for publication. Mast, R. W., E. E. McConnell, T. W. Hesterberg, J. Chevalier, P. Kotin, D. M. Bernstein, P. Thevenaz, L. R. Glass, W. C. Miller, and R. Anderson (1993). A multiple dose chronic inhalation toxicity study of size-separate kaolin refractory ceramic fiber (RCF) in male fischer 344 rats. Submitted for publication. Glass, L_ R., C. E. Easterly, T. D. Jones, and P. J. Walsh (1991). Ranking of carcinogenic potencies using a relative potency framework. Arch. Environ. Contam. Toxico% 21: 169-176. Glass L. R. and C. E. Easterly. Evaluation of the carcinogenic potency of polynuclear aromatic hydrocarbons. Submitted to Journal of Po/ycyclic Aromatic Compounds. Glass, L. R., T. D. Jones, C. E. Easterly, P. J. Wajs', (1991). Use of short-term test systems for the prediction of the hazard repr.rsented by potential chemical carcinogens. Environmenta/ Auditor, Vol. 2 No. 3: 103-169. Glass, L. R., T. H. Connor, J. C. Theiss, C. E. Dallas, and T. S. Matney (1986). Genotoxic evaluation of the offgassing products of particle board. Toxicology Letters 31: 75-83.

Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 11 PUBLISHED SYMPOSIA Mast, R. W., L. R. Glass, E. E. McConnell, T. W. Hesterberg, J. G. Hadly, D. M. Bernstein, P. Thevenaz, and R. Anderson (1993). "Chronic inhalation, intratracheal, and biopersistence studies on refractory ceramic fibers (RCF)". In Toxic and Carcinogenic Effects of Solid Particles in the Respiratory Tract.- Fourth /nternationallnhalation Symposium. Hanover, Germany. Mast, R. W., T. W. Hesterberg, L. R. Glass, E. E. McConnell, R. Anderson, and D. M. Bernstein (1992). "Chronic Inhalation and Biopersistence of Refractory Ceramic Fiber in Rats and Hamsters". In Biopersistence of Respirable Synthetic Fibers and Minerals-A Workshop. International Agency for Research on Cancer (IARC), Lyon, France. Mast, R. W., L. R. Glass, E. E. McConnell, D. M. Bernstein, G. Lemasters, C. Rice, J. Lockey (1992). "Animal Carcinogenicity and Human Epidemiology Studies on Refractory Ceramic Fibers". In Eighth lnternational Conference on Occupational Lung Diseases. Prague, Czechoslovakia. Mast, R. W. and L. R. Glass (1990). Health effects research on refractory ceramic fiber (RCF)-"Interim results of toxicologic and epidemiologic studies." In Proceedings of the Annual Conference on Fire Safetyand Thermal lnsulation. St. Petersburg, FL. Condie, L. W., C. E. Easterly, and L. R. Glass (1988). "Use of Short-Term Bioassays in Estimating Human Health Hazards of Wastewater Effluents". In Hazardous and Industrial Wastes: Proceedings of the Twentieth Mid Atlantic lnd••strial Waste Conference, M. M. Varma and J. H. Johnson Jr., eds., pp 409-419. Published by the Hazardous Materials Control Research Institute, Silver Spring, MD. Glass, L. R., C. E. Easterly, and T. D. Jones (1987). "Present and projected methods for assessing the hazard represented by complex mixtures". In Proceedings of the Third Annual Oak Ridge Model Conference. Health and Safety, Volume III: 263-273. r

Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 12 Jones, T. D., L. R. Glass, C. E. Easterly, and B. A. Owen (1987). "Rapid screening of hazard (RASH) based on maximum use of biological data and minimum use of extrapolation models." In Proceedings of the ThirdAnnua/Oak Ridge Model Conference. Health and Safety, Volume Ill: 275-284. Glass, L. R. and C. E. Easterly (1987). "Ranking of PAH carcinogenic potencies." In Proceedings of the Eleventh International PAH Symposium. ABSTRACTS/PRESENTATIONS Yu, C. P., Y. J. Ding, L. Zhang, G. Oberdoerster, R. W. Mast, L. R. Glass, and M. J. Utell. "Deposition and clearance modeling of inhaled RCF in hamsters: Comparisons with rat's results." Society of Toxicology Annual Meeting. Dallas, TX. March, 1994. Glass, L. R. "Overview of health effects of natural and man-made vitreous fibers." Presented to the Western New York Occupational Medical Association, Corning, NY. October, 1993. Glass, L. R. "Results of chronic bioassays of RCFs in rodents." American Academy of Industrial Hygiene Annual Meeting, Cincinnati, OH. October, 1993. Yu, C. P., L. Zhang, G. Oberdoerster, R. W. Mast, L. R. Glass, and M. J. Utell (1993). "Deposition and clearance modeling of RCF in the rat lung." ALA/ATS International Conference. San Francisco, CA. May, 1993. Glass, L. R. "Health considerations and safe handling of non-asbestos fibers." Presented to the 57th Annual Western New York Safety Conference. Buffalo, NY. May, 1993. . Yu, C. P., L. Zhang, G. Oberdoerster, R. W. Mast, L. R. Glass, and M. J. Utell (1993). "Clearance of RCF from the rat lung: Development of a model." Ninth Congress of ISAM, Garmisch-Partemkirchen, Germany. April, 1993. Yu, C. P., L. Zhang, G. Oberdoerster, R. W. Mast, L. R. Glass, and M. J. Utell (1993). "Deposition modeling of RCF in the rat lung." Ninth Congress of ISAM. Garmisch-Partemkirchen, Germany. April, 1993.

Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 13 Mast, R. W., E. E. McConnell, L. R. Glass, T. W. Hesterberg. "A Multiple Dose Chronic Inhalation Toxicity Study of Refractory Ceramic Fiber (RCF) in Male Fischer 344 Rats." Society of Toxicology 32nd Annual Meeting, New Orleans, LA. March, 1993. Glass, L. R., R. W. Mast, J. Chevalier, P. Thevenaz, D. M. Bernstein, E. E. McConnell, and T. W. Hesterberg. "Subacute (28 day) Nose Only Study of Size Selected Refractory Ceramic Fiber (RCF) Male Fischer 344 Rats." Society of Toxicology 32nd Annual Meeting, New Orleans, LA. March, 1993. Mast, R. W., E. E. McConnell, L. R. Glass, T. W. Hesterberg, R. Anderson, and D. Bernstein (1992). "Inhalation Oncogenicity Study of Kaolin Refractory Ceramic Fibers (RCF) in Hamsters-Final Results." Society of Toxicology 31 st Annual Meeting, Seattle, WA. Glass, L. R., R. W. Mast, T. Hesterberg, R. Anderson, E. E. McConnell, and D. Bernstein (1992). "Inhalation Oncogenicity Study of Refractory Ceramic Fiber (RCF) in Rats-Final Results." Society of Toxicology 31st Annual Meeting, Seattle, WA. Glass, L. R. "An update of health effects research on refractory ceramic fibers-Review of toxicologic and epidemiologic studies." Presented at the Third International Ceramic Science and Technology Congress and Exposition. San Francisco, CA. November, 1992. Glass, L. R. and R. W. Mast. "Critical research needs for the assessment of the health impact of vitreous fibers." Presented at the Workshop of Chemical and Biological Interactions of Glass. Bethesda, MD. March, 1992. Glass, L. R. "Health, safety, and economic issues associated with the use of refractory ceramic fibers." Presented at the Annual Meeting of the Northern California Section of the American Ceramic Society. Menlo Park, CA. September, 1991. Mast, R. W, and L. R. Glass. "The EPA's Risk Management Program: The Carborundum Experience." Presented at the BP America Annual Health, Safety and Environment Conference. Cincinnati, OH. August, 1991 .

Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 14 DeRosa, C. T., H. Choudhury, L. R. Glass, and W. H. Farland (1989). "An Integrated Exposure/Pharmacokinetic Based Approach to the Assessment of Complex Exposures. Lead: A Case Study." Ninth Oak Ridge National Laboratory Life Sciences Symposium. The Future Challenges of NEPA: Future Directions Based on 20 Years of Experience. Knoxville, TN. Easterly, C. E., L. R. Glass, and T. D. Jones (1988). "Common Scale Proportional Hazard Rating for Toxic Chemicals." Annual Conference of the Society for Occupational and Environmental Health-Toxic Wastes and Public Health: The Impact of the Superfund. Washington, DC. Glass, L. R. and C. E. Easterly (1987). "Ranking of PAH carcinogenic potencies." Eleventh International PAH Symposium. Gaithersburg, MD. Glass, L. R., C. E. Easterly, and T. D. Jones (1987). "Present and projected methods for assessing the hazard represented by complex mixtures." Third Annual Oak Ridge Model Conference. Oak Ridge, TN. Glass, L. R. "Use of short test systems for the prediction of the hazard represented by potential human chemical carcinogens." Presented to the National Toxicology Program at the National Institute of Environmental Health Sciences, Research Triangle Park, NC. September, 1988. Glass, L. R. "Applications of short term test systems to human health hazard assessment." Presented at the Food and Drug Administration, Washington, DC. December, 1987. Glass, L. R. "Novel applications of the Registry of Toxic Effects of Substances of Chemical Substances (RTECS) data base." Presented at the National Institute for Occupational Safety and Health. November, 1987. Glass, L. R. "Use of short test systems for the prediction of the hazard represented by potential human chemical carcinogens." Presented at the Agency for Toxic Substances and Disease Registry, Atlanta, GA. October, 1987.

Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 15 Glass, L. R. "Limitations of toxicologic data for use in human health hazard assessment." Presented at the Agency for Toxic Substances and Disease Registry, Atlanta, GA. October, 1987. Glass, L. R. "Applications of risk assessment to problems in the occupational setting". Presented to the Product Certification Division of the Y-1 2 Munitions Plant, Oak Ridge, TN. June, 1986. TECHNICAL REPORTS Ashley, C., P. Bechmann, P. Boymel, R. C. Brown, C. G. Burley, P. Class, L. R. Glass, L. D. Maxim, R. Waugh (1993). The Relationship Between Airborne Fibre Concentration and Diameter: A Working Paper Prepared by the ]ndustrial Members of the Ad Hoc DGXI Technical Subcommittee. Glass, L. R., T. D. Jones, C. E. Easterly, P. J. Walsh (1989). Use of Short-Term Bioassays for the Prediction of the Hazard Represented by Potential Chemical Carcinogens. ORNL/TM-1413. Easterly, C. E., L. R. Glass, T. D. Jones, B. A. Owen, R. L. Schenley, P. J. Walsh, L. C. Waters (1988). Health Hazard Evaluation of Waste Water Using B'toassays: Preliminary Concepts. EPA Report No.: EPA/600/1-88/003. Condie, L. W., C. E. Easterly, and L. R. Glass (1988). Use of Short-Term Bioassays in Estimating Human Health Hazards of Waste Water Effluents. EPA Report No.: EPA/600/D-88/132. Barnthouse, L. W., J. E. Breck, T. D. Jones, G. W. Suter II, C. E. Easterly, L. R. Glass, B. A. Owen, and A. P. Watson (1987). Relative Toxicity Estimates and Bioaccumulation Factors for the Defense Priority Model. ORNL/TM-6416. co 0