Tobacco Documents Online

R: REDACTED MATERIAL Larrv R. Glass, Ph.D.. M.P.H. REDACTED SUMMARY OF QUALIFICATIONS: • Experience in domestic and international regulatory toxicology and health issues • Career reflects progressively increasing levels of responsibility in areas of regulatory toxicology, product safety, environmental quality, and occupational health • Well-defined personal and professional standards and ethics; career reflects hard work, loyalty, and professional competence • Doctoral education in Toxicology and Risk Assessment. Post-graduate experience in analysis and interpretation of complex data-sets PROFESSIONAL EXPERIENCE 1 994-present Product Stewardship Scientist Occidental Chemical Company Niagara Falls, New York Develop strategy for product assessment, including the assessment of the potential hazards and development of risk management options. Serve as contract officer for conduct of product testing at outside facilities-review protocol, monitor study, interpret results, ensure timely communication of health research results of testing to businesses. Represent the company on committees at trade associations, regulatory hearings, inter-industry scientific committees, panels, and task forces.

Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 2 1990-1994 Manager, Health and Environmental Sciences The Carborundum Company Niagara Falls, New York Managed company-wide health sciences programs to minimize potential harm arising from the manufacture, distribution, sale, or use of company products. Managed company-wide compliance with HAZCOM, TSCA, Canadian Chemical Control Act, Hazardous Materials Transportation Act, and other pertinent regulations. Participated in the strategic planning and management of a worldwide Health and Regulatory Compliance Program (Product Stewardship Program) for Refractory Ceramic Fiber. Represented strategic company interests internationally in scientific forums, regulatory hearings, inter-industry scientific committees, trade organizations, interactions with customers, panels, and task forces. Participated in the management and oversight of multidisciplinary health effects research programs. 1989-90 Toxicologist, USEPA Environmental Criteria Assessment Office (ECAO) Cincinnati, Ohio Coordinated risk assessments of environmental contaminants as directed by CERCLA, SARA, RCRA, and other relevant statutes Reviewed quality of toxicologic and environmental studies for incorporation into risk assessments. Reviewed risk assessments to ensure their technical accuracy.

Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 3 Supervised the calculation of RQ's, RfD's, unit risks, and other determinations pertinent to the application of toxicologic and epidemiologic data. Managed the preparation and review of technical reports 1988-89 Postdoctoral Fellow Appointment to U.S. Department of Energy Postgraduate Research Program Oak Ridge, TN Toxicologist for a multidisciplinary team (expertise included epidemiology, ecology, statistics, mathematics, and health physics). Research efforts focused on the development of methods to evaluate the potential for adverse health consequences following "low-level exposures" to environmental agents. 1986-88 Joint Appointment: Visiting Scientist Oak Ridge National Laboratory (Health Effects and Epidemiology Group) Faculty Associate The University of Texas at Houston, School of Public Health (Epidemiologic Research Unit) Houston, TX Responsibilities same as the previous position.

Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 4 1986 Visiting Faculty University of Utah, Rocky Mountain Center for Occupational and Environmental Health Salt Lake City, UT Participated in the development and teaching of a "short course" on environmental epidemiology, toxicology, and risk assessment. 1984 University of Texas Health Science Center, Office of Environmental Health Houston, TX 982-83 Developed database to inventory hazardous materials on the campus. Project ensured compliance with "Right-to-Know" legislation. Senior Research Assistant 978-79 University of Texas School of Public Health Houston, TX Participated in the design and implementation of a research project to assess the in vivo and in vitro toxicity of formaldehyde. Chemist Philadelphia Electric Company/United Engineers Philadelphia, PA Responsible for chemical analysis of flu-gas to ensure compliance with Clean Air Act. ~ c~

Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 5 1977-78 Research Technician Albert Einstein Hospital Philadelphia, PA Participated in a research effort to develop a non-invasive method for the detection of thromboemboli. EDUCATION 1984-88 Ph.D., Toxicology/Risk Assessment. The University of Texas Health Science Center at Houston, School of Public Health (minors: Epidemiology and Statistics), Houston, TX. 1981-84 M.P.H., Occupational Health. The University of Texas Health Science Center at Houston, School of Public Health (minor: Industrial Hygiene), Houston, TX. 1979-81 Graduate Program in Pharmacology. Wayne State University, College of Pharmacy and Allied Health Professions, Detroit, MI. 1972-76 B.S., Biology (minor: Chemistry). George Washington University, Washington, DC. APPOINTMENTS/AWARDS 1991 Corporate Merit Award for Outstanding Contributions in Health, Safety and Environment 1990 Sustained Superior Performance Award, Office of Health and Environmental Assessment, Environmental ProtectionAgency Z\D 1987-89 Postdoctoral Fellowship, U.S. Department of Energy <= ~ Postgraduate Research Participation Program administered by c~ Oak Ridge Associated Universities '~ c,P 00 0 ~ 0

R: REDACTED MATERIAL Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 6 1982-85 NIOSH Scholarship for Study of Occupationally Induced Disease, The University of Texas School of Public Health 1981-82 Graduate Research Assistantship, The University of Texas Graduate School of Biomedical Sciences, Houston, TX 1980-81 Graduate Research Assistantship, Wayne State University, Detroit, MI REFERENCES Available upon request. REDACTED COMMITTEE PARTICIPATION Chemical Industry Institute of Toxicology • Member Representative Chemical Manufacturers Association (1994) • Dioxin Work Group • Endocrine Effects Work Group/Coalition 0 ~ Chemical Industry Institute of Toxicology (1994) a~ ~ cP • Technology Advisory Panel (TAP) on Fibers Research Program 00 0 ~ ~

Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 7 European Ceramic Fiber Industry Association (ECFIA) (1 993-present) • Industry Technical Sub-Committee on Regulation Refractory Ceramic Fiber Coalition (RCFC) (1 992-present) • Proposition 65 Task Force • Medical/Scientific Committee Thermal Insulation Manufacturers Association (TIMA) (1990-1992) • Toxicology Committee ® Medicai/Scientific Committee RESEARCH PROJECTS Longitudinal Respiratory Health Study of Employees in the Refractory Ceramic Fiber Industry: Five-Year Continuation Study of Pulmonary Morbidity and Mortality (1994-present) Role: Project management, oversight, and reporting of results Principal Investigator: James Lockey, M.D., University of Cincinnati Proposed Budget: $2,100,000 Sub-chronic Inhalation Studies of Respirable Man-Made Vitreous Fibers in Rats (1993-present) Role: Study design, project management and oversight, and reporting of results Principal Investigator: Research and Consulting Company (RCC), AG, Geneva, Switzerland. Cost: $500,000

Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 8 Pulmonary Surveillance Study of Workers Exposed to Refractory Ceramic Fibers (RCF) (1990-1993) Role: Project management, oversight, and reporting of results Principal Investigator: James Lockey, M.D., University of Cincinnati Cost: $750,000 Epidemiology Study of Workers Exposed to Refractory Ceramic Fibers (RCF) (1990-1993) Role: Project management, oversight, and reporting of results Principal Investigator: James Lockey, M.D., University of Cincinnati Cost: $2,500,000 Nested Case-Control Study of Workers Exposed to Refractory Ceramic Fibers (RCF) (1992-1993) Role: Project management, oversight, and reporting results Principal Investigator: James Lockey, M.D., University of Cincinnati Cost: $175,000 Lifetime Inhalation Studies of Refractory Ceramic Fibers (RCF) in Rats and Hamsters (1990-1993) Role: Interpretation and results reporting, project management and oversight Principal Investigator: Research and Consulting Company (RCC), AG, Geneva, Switzerland Cost: $7,400,000

Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 9 Lifetime Multiple Dose Inhalation Study of RCF in the Rat (1990-1993) Role: Interpretation and results reporting, project management and oversight Principal Investigator: Research and Consulting (RCC), AG, Geneva, Switzerland Cost: $2,500,000 Computer Modeling and Assessment of the Deposition, Clearance, and Retention of Refractory Ceramic Fibers (RCF) in the Lungs of Rats and Hamsters (1992-present) Role: Project management and oversight Principal Investigator: M.J. Utell, M.D., University of Rochester Cost: $80,000 Worksite and Job Task Exposure in Humans Exposed to Refractory Ceramic Fibers (RCF) (1990-1992) Role: Project oversight Principal Investigator: Morton Corn, Ph.D., Johns Hopkins University Cost: $2,500,000 RESEARCH PUBLICATIONS Yu, C. P., L. Zhang, B. Oberdoerster, R. W. Mast, L. R. Glass, and M. J. Utell (1993). Deposition modeling of refractory ceramic fibers in the rat lung. Journal of Aerosol Science. In press. Yu, C. P., L. Zhang, G. Oberdoerster, R. W. Mast, L. R. Glass, and M. J. Utelf (1993). Clearance of refractory ceramic fibers (RCF) from the rat lung: Development of a model. Environmental Research. In press.

Larry R. Glass, Ph.D., M.P.H. October 21, 1994 Page 1 0 Yu, C. P., J. Ding, L. Zhang, G. Oberdoerster, R. W. Mast, L. R. Glass, and M. J. Utell (1993). Deposition and clearance modeling of inhaled kaolin refractory ceramic fibers (RCF) in hamsters-comparison with rat's results. Submitted for publication. Mast, R. W., E. E. McConnell, R. Anderson, J. Chevalier, P. Kotin, D. M. Bernstein, P. Thevenaz, L. R. Glass, W. C. Miller, and T. W. Hesterberg (1993). Studies on the chronic toxicity (inhalation) of four types of refractory ceramic fibers (RCFs) in male fischer 344 rats. Submitted for publication. McConnell, E. E., R. W. Mast, T. W. Hesterberg, J. Chevalier, P. Kotin, D. M. Bernstein, P. Thevenaz, L. R. Glass, and R. Anderson (1993). Chronic inhalation toxicity of a kaolin based refractory ceramic fiber (RCF) in syrian golden hamsters. Submitted for publication. Mast, R. W., E. E. McConnell, T. W. Hesterberg, J. Chevalier, P. Kotin, D. M. Bernstein, P. Thevenaz, L. R. Glass, W. C. Miller, and R. Anderson (1993). A multiple dose chronic inhalation toxicity study of size-separate kaolin refractory ceramic fiber (RCF) in male fischer 344 rats. Submitted for publication. Glass, L_ R., C. E. Easterly, T. D. Jones, and P. J. Walsh (1991). Ranking of carcinogenic potencies using a relative potency framework. Arch. Environ. Contam. Toxico% 21: 169-176. Glass L. R. and C. E. Easterly. Evaluation of the carcinogenic potency of polynuclear aromatic hydrocarbons. Submitted to Journal of Po/ycyclic Aromatic Compounds. Glass, L. R., T. D. Jones, C. E. Easterly, P. J. Wajs', (1991). Use of short-term test systems for the prediction of the hazard repr.rsented by potential chemical carcinogens. Environmenta/ Auditor, Vol. 2 No. 3: 103-169. Glass, L. R., T. H. Connor, J. C. Theiss, C. E. Dallas, and T. S. Matney (1986). Genotoxic evaluation of the offgassing products of particle board. Toxicology Letters 31: 75-83.