Philip Morris
Response to Aubort
Fields
- Area
- REIF,HELMUT/OFFICE
- Type
- REPT, REPORT, OTHER
- Document File
- 2028397492/2028397799/Missing
- Named Organization
- Tc126
- Tno
- Wg6
- Tno
- Request
- Stmn/R1-071
- Stmn/R2-038
- Master ID
- 2028397493/7798
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- 2028397797-7798 Barclays
- Litigation
- Stmn/Produced
- Site
- E5
- Named Person
- Aubort
- Etournaud
- Fine, L.
- Etournaud
- Date Loaded
- 05 Jun 1998
- Brand
- Barclay
- UCSF Legacy ID
- kal56e00
Document Images
TC126/WG6 N58
'.
RESPONSE TO AUBORT
The essential argument of the paper by Aubort and Etournaud is that
smokers of BARCLAY obtain more smoke than smokers of other brands of
nominally 1mg delivery. This is basediupon a.technique of sampling
from the mouthsof smokers immediately following a puff.
Aubort's mouth sampling experiments were undertakeni without the benefit
of knowingihow smoke is actually dispersed'in the human mouth. As has
a7ready been described in the Introduction, there are major diifferencess
in the smoke dispersion between BARCLAY and conventionally ventilated
cigarettes. These in vitro differences have been confirmed in vivo by
Dr Louis Fine using fibre optic viewing. Video tapes of this are
available.
There are several fundamental errors in the approach adopted by Aubort
andlthese are set out in some detail initwo critiques (N59 and N60)..
Atnong the objections to the Aubort mouth-sampling technique is the
failure to appreciate the crucial importance of sampling position.
It is also important to note that Dr Aubort does not differentiate
between cigarettes with a nominal delivery of 7-16 mg tar.
Experiments performed inde~pendentlyby,TNA1,Apelidoorn (N61), show thatt
sampling position critically affects estimated tar intakes. The data
is shown by anialternative graphical presentation (N62).
Aubort's laboratory experiments cannot represent everyday smoking,
dependingias they do on interventi'onwith the~subject.
