Tobacco Documents Online

Shimizu, H., Morishita, M., Mizuno, K., Masuda, T., Ogura, Y., Santo, M., Nishimura, M., Kunishima, K., Karasawa, K., Nishiwaki, K., Yamamoto, M., Hisamichi, S. and Tominaga, S., "A Case-Control Study of Lung Cancer in Nonsmoking Women," Tohoku Journal of Experimental Medicine 154: 389-397, 1988. This case-control study of women in Nagoya, Japan (90 nonsmoking cases and 90 age-and hospital-matched controls) was conducted to investigate the significance of "'passive smoking"' and other factors in relation to lung cancer etiology. Elevated RRs were reported for smoking by case's mother or husband's father living with the case (RR = 4.0, p < 0.05 and RR = 3.2, p < 0.05, respectively) [CIs were not given]i. No association was reported for lung cancer risk and husband's smoking (RR = 1.1) or for ETS exposure at work (RR = 1.2). A RR of 4.8 (p < 0.05) was reported for occupational exposure to iron or other metals; an elevated, statistically nonsignificant RR of 3.3 was reported for occupational exposure to coal, stone, cement, asbestos, or ceramics. The authors stated that no appreciable differences in food intake were observed between cases and controls, although the assessment of dietary differences was not detailed. The authors also present calculations for statistically nonsignificant elevated risks associated with the use of kerosene (RR = 1.6) and coal (,RR = 1.7) in the household heating system. An elevated RR of 2.0, which was not statistically significant, was reported for personal history of silicosis.