Tobacco Documents Online

Garfinkel, L., Auerbach, O. and Jouert, L., "Involuntary Smoking and Lung Cancer: A Case-Control Study," Journal of the National Cancer Institute 75(3): 463-469, 1985. This case-control study, conducted in New Jersey and Ohio, included 134 cases and 402 age- and hospital-matched controls. Lung cancer cases were ascertained using hospital records and cancer registries. Controls had been diagnosed with colon-rectum cancer. All cases were histologically confirmed. Some proxy interviews were conducted, usually with spouse or children. One table shows the variation in ORs related to respondent type; for instance, based on questions about husband's smoking habit, an OR when the case responded was 0. 83 ; when the husband, 0. 77 ; and when the case' s child, 3.57. Exposure questions were asked regarding husband's smoking, smoking by others in the home, smoking in the workplace and smoking by others during childhood. ORs were calculated for four methods of classifying,smoke exposure: "exposed to smoke over last 5 year," OR = 1.28 (95% CI 0.96-1.70); "exposed to smoke over last 25 year," OR = 1.13 (95% CI 0.60-2.14)~; "husband smoked,'° OR = 1.22 (95% CI 0.97-1.71); and "husband smoked at home," OR = 1.31 (95% CI 0.94-1.83). Additionally, for women whose husbands smoked -40 cigarettes/day, an OR of 1.99 (95% CI 1.13-3.50) was calculated. For those whose husbands smoked ?20 cigarettes/day, the reported OR was 2.11 (95% CI 1.13-3.95). For exposure in the workplace, ORs less than 1.0 were reported. Exposure during childhood was associated with a statistically nonsignificant OR of 0.91.