Philip Morris
Deaths From Lung Cancer and Ischemic Heart Disease Due to Passive Smoking in New Zealand
Fields
- Author
- Lee, P.N.
- Document File
- 2023511660/2023512308/Ets: Heart Disease 930900
- Area
- SCIENTIFIC AFFAIRS/BLACK LATERAL OLD S&T
- Type
- PSCI, PUBLICATION SCIENTIFIC
- BIBL, BIBLIOGRAPHY
- Master ID
- 2023511661/2307
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- Characteristic
- EXTR, EXTRA
- MARG, MARGINALIA
- Named Person
- Jackson
- Kawachi
- Pearce
- Wells
- Kawachi
- Litigation
- Okag/Privilege Withdrawn
- Okag/Produced
- Author (Organization)
- New Zealand Medical Journal
- Pn Lee Statistics + Computing
- Site
- R529
- Date Loaded
- 24 May 1999
- UCSF Legacy ID
- cic02a00
Document Images
NEW ZEALAND MEDICAL JOURNAL
What is of greater concern is the way in which your
ndents have sought to obecttre the message of our paper.
This is that patients in our study were unhappy about
cliar hich had' inflated at 24~+ per annum. No amount of
analysis o total fee: of GST or of general practitioner incomes
wiL change ese facts. Nor will they be altered' by claims that
patients have right to determine what they deem to be a fair
and reasonable c t for medical care.
Further. some o our correspondents imply that the purpose
of our paper wu to c cise general practice and to bring general
practitionen into disre ' te. This is not so. as will be seen from
our provious article (ul on ' topic: The purpoae of the present
article was not to denigrete e efforts of general'~practitioners
but rather to bring to attention curnent public perception of the
cost of their services. We woul hope that this evidence will
contribute positively to policy atte ts to devise a fee structure
which ensures that family doctors ve a fair return for their
efforts while at the same time protecting tients from the current
inflation in patient charges which has large been caused by the
way in which the relationships between the tal fee and GMS
are set.
G2
I
~S 7r >
23 AUGUST 1989'
proportion of smokers as nonsmokers. As argued at iength
elsewhere 16-12~ this biaa can produce an artefactual association
of a similar magnitude to the association ciaime&by Kawachi et
aliftl to be due to passive smoking. Wells 121 correction for this
bias was totally inadequate, failing to allow for the possibility
of miscltssified current typical regular smokers, whereas a recrnt
summary of data from large studies shows an average rate of
about 4% lul.
Although there is virtually no epidemiological data on risk in
relation to workplace exposure to passive smoking. Kawachi et
al (Il present estimates based on unjustified extrapolations from
the spouse smoking estimates. which are themselves hopelessly
biased.
The authors present numbers of deaths with ranges, so giving
the uninformed reader spurious idea of accuracy. When one
considers no major authority has yet concluded passive smoking
causes IHD: it is difficult to see what usefulI meaning one can
attach to the cited lower limits of 39 IHD deaths for spousali
smoking and 62 for workplace exposure.
Peter N' Lee (Mr);.
PN' Lee Statistics and
Computing Ltd.,
Cedar Road.
Sutton,
Surrey' SM2 5DA. UK.
D M Fergusson.
L J Horwood,
F T Shannon., Christc
Developme
Christchurch h Child
Study,
pital.
e", , F
Dy _
i'
Christch h.
1. Fargusan DM. B..uttw AL SAamoo FT. Maveal wud.esaoente pnmrry. Y.Nth
tan NZM.d:J 1e61-9.-291'.a.
Oeaths from lung canc.r and ischaemic heart disaase
due to passive smoking in N.w Z.aland
Kawachi, Pearce and Jackson )l,i estimate that passive smoking
causes 273 deaths per year in New Zealand. 30 from lung cancer
and 243 from ischaemic heart disease (IHDI. Some 65% of'these
deaths are attributed to workplace ezposure, the rest to spousal
smo{dng: Tbae estimates are sdentifically'unjustified. Too much
weight is given to fragile epidemiological data, major sources of
bias being totally underestimated. Too little weight is given to
evidence that nonsmokers have very low exposure to tobacco
smoke coIIStltuents..
The evidence that passive smoking increases risk of IHD is very
unconvincing. The authors t1I'cite a metaanalysis by Wells 1z1ifor
their estimate of risk in relation to spouse smoking. This is based
on 7 studies, maay of which involve unacceptably small numbers
of cases, eg, as low as two deaths in women married to never
smoking husbands 136 The two studies with adequate numbers
are both open to question.
One of these ie the Japanese prospective study hal Walls cited
results from 17 years follow' up (6) which claimed' a ai,gnificant
trend in IHD in relation to spouse smoking, but failed to m.ntioa
that this finding significantly Ip <0.001) 'conflicted with an ear}ier
report, based on 14 years follow up which claimed no association
whatso.ver!
The other is the Maryland prospective study pl Iwhich reported
34% and 24% increases in IHD in men and woman in relation
to spouse smoking. This study has many featurea that we
notawortby. It made no attempt to follow up paopl* moviog
outside Washington County, thus missing large numben of
deaths. It found no doee response relationahip. It failed to collect
data on a whole raagp of possibly relevant confoundiisg factors.
Tboae it did adjust for (Ylge, marital statua, ye.n of school, qualityy
of housing) had' an enormous effect on rdative risk. changins
estimates from 1.17 to 131 in - and fiam 066 to 1.24 m wnmed
emphasising the fragility of the results.
The evidence relating passive smoking to lunt eancer is mon
extensive than for IHD. being based on 27 published studiea, not
13 as Kawachi et aI sutt!' WhiL there is an asaooatioo of spouse
smoking to lung cancer risk that cannot plausibly be a:plai6ed
by ixtblicatian bias. it cannot be reliably inferted this results from
a causal effect of pusive smoking. In the first place, exposure
of nonsmokars to smoke constituents is very low. Thus typical
nonsmokers retain only about 0.01-0.029G of the amount of
smoking related particuiates retained by a smoker (Tl.
Furthermora, there are various sources of persistent bias in the
epidemiology, a major one caused by misc1~--ificstioo of a
1. Kaw.e)u.1. Peoro NE. J.aiam RT Douhs bam hieg ueor and umwnc A..rtatrn dn" tcp..ev. amobea mliw
7r1.e4 tiZM.tl J 1969 102337-.0
2W.ti. AJ An.rum.u of aAutt.mortaAkty.te tb Uaet.dStatw fiompaaav..motu6
Eevvaom.nv Idt.rnauod.l 11il6. 1.. 24945
3. G.Aaad C. B.r..uCmnm E. Su.~ L.t.1 Eftactu of pe.n- soaot-
hrn dlr. mart.lny m om®oY~a Lvts. atL .moY.n. Am JEqd.md 1966. ,121..
y4}50
4 Hln.yama T Veo-.mdom~ -w of,hrry..aa4,s h.r..hu~r n.kof liusa cmt-
a ttutlyhom Jipan Br M.dJ 1961.2a2..1156S. Hu.yama T l.un6 csner m Jap.n.ff.ee. of nutruon .ad
p..u...mot'.- . Ic MiWI i
M. Ca.n.. P: .d.. Luee c.eer ala aedm p.wretm K.. Yort V.r4y Cl.ar
laam_, 1964 .: 17S%
6. Hdan. KJ. S.ndl. DP: Gem.meY C W. Ch. E. Howes mar mmn.a4ty to L+we ac6 ueatrs. Am J Epm.omi 19M.
1Zf:.l1SYJ.
7~ Arupdd A. St.Ata6 T. W.ekam J Y~ makam, IaY( cm~ naku flem .ayo.ttn to
prrtuulitw tobaQO ®a4a. EortemmrIwmre.ue..l.1tQ7, 13. Mi26B. Lsa PN, P..arv. ®oktn6.ed 4w6 ~
Aam.cm a rwrlt of bu.'.Hua.a Tos.ea/'
1967. 6~ 51724
9. La PN. MisJS6raum of~y.haMt. mdPrv. aabo.. A.i.vrA of td.
.vdaon. tntre.t+mal AucEUw of OantFamd'rd H.NthSuyp+.mst: H.GaOrr
Sprmrrv+rla.., 1tie6:
10; lr PH An altarnaav- mcp----pmfor the uevaaG raY of ptn6 o.eet m na4mauYrs
marrrE to amoi'as. !c Prry R. Itnt P'W. d. In6av aed .mtirt.r yu.4ty tsOm
S.lar. 1 YlB. 1 YP56.
11. Laa Ph'. Pa...w ~a6. F.et or6cum' Prpe }r.ammmud .tCaLf.m oa Pe~et
and Funue of ls6es Au Qw{ttr A.ad mBrvairLm Feen.ry It16. 1909
.
12 ~ 1- PN . Probi.m. mmtrpr.ueg pd.mroiopeal d&ta P.P.r Pe..mmaud at Ca1~
oaArrmant of IeAa~~y- H..ed. 6.Id mH~ v Fetiru.ry1YY1: IM9.
iled vasectomy
A t ACC appeal case was published 'm the Otago Daily Timn
and I it vary disturbing Isee Medicoiegal p 4531: This couple
was a ca6apeosatioc aft,er the alleged fa0urs of a va..ctomy
part t Om-^' Hoepital in 1979. A.her this operation it
took nine ths befon the sperm count was sero. Nearly five
years later appellants wife fall pregnant. Tseee happanings
can be eaaily lained in that tb. vasectomy was performed
correctJy but the count took a long time to reach zero
because the patiemt as alow to ej aculat. all the aperm from his
body. Ttis u qufte seen. 'Ib pregnancy resulted from
recanaalisation of tbe v dafeens and can occur once in about
every 500 vasectomies.. Y 'te the above asplanaoaaa, anme
other surgeon has stated it is standard medical practice to
recommend a rapeat v after three or at the most four
positive sperm tests after a v y. Judge Middletan has
accepted this surYeoa..vid.ooe as and this psaad.d th.
judge to allow the c-1aiia If the facta case an as I reed thtm
in the Otago Daily T'uaee tben,then a clear miscartiage
of justice.
Compensation has bean wrmgfy awarded a docttr wrongly
accused of negligenee. This case may set a f Qrec.deat. Tbe
Accident Compansation Corpontion abould not allowed to
accept this appeal dewion and' this case should a higher
court
.ar. -rr
