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THEME 95. SESSION' 37 COHORT STUDY 1141 li( i A( I f 1N`il 11(' Ifl i'A'a:1I VI 'i^1111t I lY{i I II G`flli'('U11`~ I II Ali 1 I1 nO l rllrtl S' Aii ~1IIIH N111-I)AY AI)1!t Nl 1~ 1''i IN' i']11i II (11iN(A. larrE•r,cr I f3u#' It:r Adventi: t 4iE•:alt',h Dcp:mluwul, N(l Itox 14, (:nrckorn, Now `'>tnrFhr WAIe;;:, 2072 Aust.ralia The relaiti'on,hilr nf p~tssive smnkCny tu ttT r: incidcrrac ul r•anccrrs, fatal irrchemic hcart. disease and a1l nutural causa mcrrii among, Cal'ifinrrrian, SFVenth-dey Advc`ntia:, wnt; invcatigirtGd in 1'7F1Fi. frum lhC 3~ 1" ~ yJbjpctu nC 1he Arlvorrl ir:l Nr:rl ll,i SturiY rcahnrl ( 15t7fi-1c)f3Z) r lwq sr:b-clruu;rs werr. :;cJr-rtcd In c:vulu:rtr Ghe rn:;car'cnc tlur••,:l iurrn. Onc, the spouse pair5 rutrnr!', rrurr.i:a.rc{ crf 11,i mrrrrrc:cl crrulrlTttic .r.rnrrd was rr r}rnup of 6,467, ::rrbjrct::;, rcli tcr ;r;c the AttEiM0f1 c-rrhronl, whn, wcrr, inv»lvr.d in rr r.urarrtrrrr:nt :rir prrlIul rnrr ::tr,rty. fullnw-ulr f'ut :fsf:crt;riruocnt nt cruuct:r jut•jdi:nrr. .rnd n,ur'ii was, trrurr 1976 to 1982. Passive smoking exhu::urc for the "spouse pairn"' was based on the hu.:,band's srnoking stalus in marriaye. For the AHSMOE cohort Environmental Tohacrc, Smnkr (I'15) exposure wa:r based on the number of yeary livecl with and the rnunber of ycars worked with a smoker. f or nUn-mmnk iii fcmilliP.i nf 1•fhQ fijlflllSC palr:i tiVhVI'tr age-adjustedl rete raticr.m arie] (9'a % C.1.1 For each nulrcrnre reprc.r.nt those fcmalc5 married ln a smuker rnmlparvd to those VrmAler, married tto a non-smoker. l rmrl ranrr•.r• ItH : Z'.111' ( n. 39-H . 7`I ), a l l :;mok f rrq rrlated cancers iM = 1.22 (F1.G1-2.A4); enrvi'craal c:rncc~r fiit _ 4.f3A ('1i.33-17.6f,) srnct t+l l rrK•iclr~nt c:rrrt•cr!: {t!i _ 1.21) (f1.')G-1.'j4). I nr !'nrralr:•:; marrir:d Lu c•r,rrrul :rmrrkrrr:r I lrr.rr w:r:r itrrrcarc:r:cd r isk for fJCal 1H0, RR = 1.411 (t1.51-5.84). Nh efFect wu:: ubserved fvr all natrrral' cause mortality. tior the AtISMOG cohort the results were less consis- tent by type of exposore mr.;isure and outcome. The small number nf cane; for some oirtrnmes and' the probable misr.3assification of pas:;ive smoking exposure limili the ability to achievc conclusive results. However, the rssults indicate on adverse effect for F1S r.xposure and are consi'stent with uthcr reported results. C1~~s~~~1 ~~ ~1\ ~--~-ti l 6 1G u C C C C, Vi~ \A p(-tVL--,