Tobacco Documents Online

~ ; RESEARCH PROJECTS IN 1990, IN VIVO STUDIES PROJECT SPECIFICA TION STA T US Histopa thological effects of the 21-d inhala tion, ra t inhaled MS and SS of cigarettes having different nitrate concen tra tions in the filler Acu te oral toxlci ty of a fla vor oral administra tion, rat Biokinetics and meta bolism of i. v. administra tlon, nicotine ra t Ind uction of SCE and CA 5-d inhala tion,, ra t foll o wing exposure to E 'formaldehyde vapor ' FlowcYtometrlc determination of 1-d and 3-d I ! reacti ve cell prolifera tion in inhala tion, ra t the respira tory tract after in vi vo exposure to formaldehyde , experimen tally finished, under eval ua tion experimen ta11y finished, under eval ua tion experimen ta11y running experimen ta11y running experimen tally running and acrolein vapor SsZBCOMQZ

PROJECT SPECIFICA TION - STA T US ~ Acu te eye irrita tion of a fla vor topical applica tion, start of experimen t rabbit • scheduled for CW 12 Acu te skin irri ta tion of a fla vor topical applica tion, start of experimen t ra bbit sched uled for CW 12 I ~B3stops thalogical effects of the 90-d inhnla tion, ra t start of exper.imen t 'inhaled MS of cigarettes ha vinB sched uled for CW 21 4ifferen t addi tive concen tra tionar in the filler Biological aEti vi ty of 21-d inhala tion, ra t, start for experimen t inhaled fresh and "ETS- scheduled 4th quarter like" S5' ss2s€oEzo9 ~