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R: REDACTED MATERIAL . WILLIAM H. BEERS REDACTED Administrative Experience 1991 - Present Senior Vice President, The Scriups Research Institute Secretary and Member, Board of Trustees 1990 - 1991 Senior Vice President for Research. Scripps Clinic and Research Foundation 1987 - 1991 Associate Director, Research Institute of Scrinps Clinic Responsible for day-to-day operations of the Institute which has a staff of approximately 1,300 employees, 500 of which hold advanced degrees. Coordinate and plan construction, renovation and installation of major equipment. Maintain coordination of activities with the parent organization, Scripps Clinic and Resea--ch Foundation. Supervise institutional support services, and have administrative responsibility for Animal Resources. Coordinate and negotiate various arrangements with industry and other institutions. Oversee budget and expenditures. 1983 - 1987 Director of Undergraduate Studies, Department of Biology, New York University Was responsible for the academic, curricular and advisement components of the undergraduate program in biology. 1978 - 1980 Chairman, Department of Biolomr, New York University Directed the Department of Biology which is composed of 21 full- time faculty, 45 non-faculty staff, and more than 1,000 students. Negotiated and administered a Departmental budget of $1.6 million in fiscal year 1980. Responsible for the planning and implementation of a five-year development plan to substantially upgrade the Department of Biology that included- 1

e 1_ A 65,000 square foot, $12.5 million research complex. This involved the conceptualization of a scheme for an effective research center which would be adopted to future needs, the selection of appropriate architects and consultants, and intense involvement in all aspects of the design work. 2. The recruitment of highly qualified, research oriented faculty members to staff the center. 3'. A complete restructuring of the graduate and undergraduate programs. Conceived and instituted the development of an objective-based, criterion-referenced introductory biology course which relies heavily on interactive video instructional units. Involved in all aspects of program development and production. Redesigned the administrative organization of the Department; instituted procedures to improve support functions of the office and initiated a complete review and revision of Departmental procedures to maximize staff efficiency. Conducted externally- funded research in female reproductive biology and supervised operations of research laboratory. Served on numerous University committees, including the Arts and Science Graduate School Task Force and the University-wide, Presidentially-appointed Research Council. Academic Experience 1991 - Present Member, Denartments of Cel1 Biolocty and Molecular Bio2oav. The Scripps Research Institute 1987 - 1991 Member. Department of Molecular Biolocxv, Research Institute of Scripps Clinic 1978 - 1987 Professor, Degartment of Bioloczy. New York University, Professor. Department of Cell Biology. New York University Medica School Conducted research in female reproductive biology. Maintained external funding. Taught graduate level courses; supervised pre- and post-doctoral students. I 2

R: REDACTED MATERIAL 1973 - 1978 Associate and Assistant Professor of Cell Biology, the Rockefeller University Conducted research on female reproductive physioYogy. Acquired and maintained full external funding. Taught graduate level courses and supervised doctoral dissertations_ 1971 - 1973 Postdoctoral Fellow. Department of Physiology and Biophysics, University of Il15.nois. Champaictn, Illinois Conducted research in female reproduction. Educational Backcxround " Graduate: The Rockefeller University, New York, New York, Ph.D. (Biochemistry and Pharmacology) Conferred June, 1971. Undergraduate: Harvard University, Cambridge, Massachusetts, A.B. (Biochemical Sciences) Conferred June, 1965. Professional Affiriations REDACTED Awa rd s Rockefeller Foundation Special Postdoctoral Fellowship in Reproductive Biology Public Health Service Research Career Development Award Dean's Distinguished Faculty Award (NYU) 3

Publications See attached listing References Furnished upon request 4

WILLIAM H. BEERS Research Publications W.H. Beers, A. Cerami, and E. Reich. An Experimental Model for Internal Denaturation of Linear DNA Molecules. Proc. Natl. Acad. Sci. 58:1624 (1967). W.H. Beers and E. Reich. isolation and Characterization of clostridium botulinum Type B. Toxin. J. Biol. Chem. 244:4473 (1969). W.H. Beers and E. Reich. Structure and Activity of Acetylcholine. Nature 288:917 (1970). W.H. Beers and E. Reich. Structure and Acetylcholine - Reply to Chothia and Pauling.. Nature 232:422 (1971). W.H. Beers. Follicular Plasminogen and Plasminogen Activator and the Effect of Plasmin on Ovarian Follicle Wall. Cell 6:379 (1975). W.H. Beers, S. Strickland, and E. Reich. Ovarian Plasminogen Activator: Relationship to Ovulation and Hormonal Regulation. Cell 6:387 (1975). S. Strickland and W.H. Beers. Studies on the Role of Plasminogen Activator in Ovulationl In Vitro Responses of Granulosa Cells to Gonadotropins, Cyclic Nucleotides and Prostaglandins. J. Biol. Chem. 251:5694 (1976). W.H. Beers and S. Strickland. Involvement of Plasminogen Activator in Ovulation. In Novel Aspects of Reproductive Physiology; 7th Brook Lodge Workshop on Problems of Reproductive Biology. (Spillman, C.H. and Wilkes, J.W., eds.) pp. 13-26, Spectrum Publications, New York. (1978). T.S. Lawrence, W.H. Beers, and N.B. Gilula. The Transmission of Hormonal Stimulation via Cell to Cell Communication. Nature 272:501 (1978). W.H. Beers and S. Strickland. A Cell Culture Assay for Follicle Stimulating Hormone. J. Biol. Chem. 253:3877 (1978). N.B. Gilula, M.L. Epstein, and W.H. Beers. Cell Communication and Ovulation: A Study of the Cumulus-Oocyte Complex. J. Cell Biol. 78:58 (1978). N. Dekel and W.H. Beers_ Rat oocyte Maturation In Vitro: Relief of Cyclic AMP Inhibition by Gonadotropins. Proc. Natl. Acad.. Sci. 75:4369 (1978). 5

T.S. Lawrence, R.D. Ginzberg, N.B. Gilula, and W.H. Beers. An Analysis of Hormonally Induced Morphological Changes in Cultured Rat Ovarian Granulosa Cells. J. Cell Biol. 80:21 (1979). S. Strickland and W.H. Beers. Studies of the Enzymatic Basis and Hormonal Control of Ovulation. In Ovarian Follicular Development and Function. (A.R. Midgley, Jr. and W.A. Sadler, eds.) pp. 143- 153, Raven Press, New York (1979). W.H. Beers. The Transmission of Hormonal Stimulation by a Cell Contact Dependent Mechanism. In Vitro Studies and Implications for Hormone Action In Vivo. In Hormones and Cell Culture, Cold Spring Harbor Conferences on Cell Proliferation, Vol. 6 (G. Sato and R. Ross, eds.) pp. 611-621, Cold Spring Harbor Press, Cold Spring Harbor, New York (1979). N. Dekel and W.H. Beers. Development of the Rat Oocyte In Vitro: Inhibition and Induction of Maturation in the Presence or Absence of the Cumulus Oophorus. Dev. Biol. 75:247 (1980). T.S. Lawrence, N. Dekel, and W.H. Beers. Binding of HCG to, Rat Cumuli Oophori and Granulosa Cells: A Comparative Study. Endocrinology. 106:1114 (1980). W.H. Beers and N. Dekel. Intercellular Communication and the Control of Oocyte Maturation. I_}r Dynamics of Ovarian Function. (N. Schwartz and M. Hunzicker-Dunn, eds.) pp. 95-104, Raven Press, New York (1981). N. Dekel, T.S. Lawrence, N.B. Gilula, and W.H. Beers. Modulation of Cell-to-Cell Communication in the Cumulus-Oocyte Complex and the Regulation of Oocyte Maturation by LH. Dev. Biol. 86:356 (1981). P.J. Olsiewski and W.H. Beers. cAMP Synthesis in the Rat Oocyte. Dev. Biol. 100:287 (1983). W.H. Beers and P.J. Olsiewski. Junctional Communication and Oocyte Maturation. In Gap Junctions (M. Bennett and D. Spray, eds.) pp. 307-314, Cold Spring Harbor Press (1985). H.M. Lacker, W.H. Beers, L.E. Meuli, and E. Akin. A Theory of Follicle Selection: I. Hypotheses and Examples. Biol. Reprod. 37:570 (1987). H.M. Lacker, W.H. Beers, L.E. Meuli, and E. Akin. A Theory of Follicle Selection: II. Computer Simuiation of Estradiol Administration in the Primate. Biol. Reprod. 32:581 (1987). AIV 6

N.Dekel, D. Galiani, and W.H. Beers. Induction of Maturation in Follicle-Enclosed oocytes: The Response to Gonadotropins at Different Stages of Follicular Development. Biol. Reprod. 38•517 (1988). 7