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R: REDACTED MATERIAL CURRICULI1Af V1TAIi. Ronald Olcun, 1t. D. Da(e-of f3irth; Marital S?atus: Sucial SecuriCy: ED 11 CA.T.InN 516 University of C'atifornia, Los AatGeles, Cali,fornia 1930-190, I3. A. tinircusity of California, Sin Frnnciscoy Californi'a- 19G4-1953 School of :Ordicine 1953 RL D. Pharmacolo•U,v 1955 1<'!. S. T RA I,~'1:CG• Teachin ; Assist:mt,, L•nicersi0yy of Califo:-iia Feb 1953-Jutc-- 1^53 San Franci:aco, California Intern, Genera), lbedical &. Sut-wal Hs7spital 195s-193s VeLeviins At)nrinistration I•)'os, ital . Los Aa;uclcs, C'aliformia Itevieltnt, Vt;tcro.cs A:Jnair.i:.trr.Lion 1losi:ital 1959-1061 T.os AngcTcs, CaLi,'rrrtia Fc(k sv, Clittics.l Pharmacolo„;v„ Johns IToPlcins Iiospit: l 1861-1JC3- 13:31timore, .llnryl¢nd PRESENT :1PA'n1\T Mf:1TS llirec6o r, Clinical Pharmacology, Ceclmrs-Sittai Medical Center Los Angelcs, California . July 19,33-Presc^t Assi;t:u t Pnofessor of Pharmacrology (iu Rcsi(7cncc). / Univarsity of Cali:fnrnia, Los An;eles, California _ Assistant Professor of \Iedicine . . UitivcrsiGy of California, Los AngeCcs, Califoania Associrde I'rofc:sso.r Sirciicine & 3fedicali Phernmrolofw &Thenapcutics Sept 1963-Presc.a Sept I9G3-June 1:^?0 Ju1y 1970-Presc>'. University of C'alifoi•nia, Irvine-Califoraia Colltrl;cof i.;ealcinc Resetercli l?hcn•r.incoloc;ist,. VeLerans Adntiesi::ttation flonpital Sepulvecia, California Const+ltant in Ph;nrniac„ibt;p . Slate of Cvlifornia, IJcparttnent of Public Health A[ICatdin„ Physirian in C:urdinliogy, t'aC<arans AdminG;tr:;tiott llospital 19G4 - 1971 , ItSG9 - 1971 1969 - Presen. LosAn;;elos, C'u1i{onei:c zo1so4s1zs

517 CCIIRRICULU1i VIQiAE Ronald Oi;lur, M. D. - PR1;SENTAf'I?C7';°I'\ilf.*T1'S fcontinucd y Scienlifi~c Advisor to lhe P,oatYt of I)irectors, Cerfa~rs Sinai~ "~Icelical Cemter 1,9G9- Prosent AssociaPe B)tlilor oL 'utinual ]t®ciow of Marmccol'opy,1970 Attending Staff in InFoxmal, `Ictflci-rse (?:cllhiolc,,i) 1970 CCounty of Los :kn2;eldbu'Ihor G.r,~,.a~rad' flo;hiGnl Los Jii^.;clc:;, California I'clbovr, AmcaricsnC'cslicr.e of C'liauca] P}iarnmctalcy;y Juna R, 1974 3-'ROF7`S.`~[O L SOCIP'TF Sigma Xi .. ' . 19JS . Amcrica n Federn'ibn for Clinical[ Ilc-earch~ 1961, Amcric..ui Association for Adn•ancc.-nenG of Science 19G1 New i'arl; .hcnd'erny of Sciences - 1961 Ame:ric;cnFnciehfor Phars aco1o<<; & 1:xlTCri:ncntal 'Ul:ernpcnitPc.s 1968 An)~erie. n-u,f C'1'eica!']"o ir 1968 Amcrican `;`ociw.}'firu Ciir,W T'hcrtapcutins 1971 SPI1;,CL1L AVt',XItI7S P,;}1O.NORS LcUge Prrreintire Mcrolicine r1aatY1 Petr June 195S I Universitp of California Medical Cender

13I197.10GILM)1fY Ronald Olcun 1. O'r,un, R. , and Elliott, 11. \1', : Acute Pharnnr.c•olo;;ic•rrll Studies of Sonlc New itlorlnliino Derivative.s. J. Pharmcol l:y). & Tlhur. b2-1:225-25D, 1958. 2. O1tun,R.. IJcI,!on, S. C. , and Lasarna, 1,: Thc Gffucts of rtgqragation, Dle•ctri!c Shnckand Adrencri,(ic• Plocl:in~ Drugs on lnhibit'ion of theN'tithing S)'nrlrotne, J. 1'htu•tntiacol. l;xp. &'1'her 193 (i):107-1679, 1903 3. Wilson, Id. , Olam, R,.: The Acoite.llennod1nrnmic 1:ffects of Diar.oxide in 1ian. Circulation 2 :8f1-93', 1,963 4. A1',nlff, F. lV. , P;+rmdc•y„ 1V. AC'. ,AV'hito, K. and Okun, R. : Drug Induced Diabc.t.es. J,S\1A i;~;i:5(Jti-a7-1, 19G3 Wilson, 11`. R. , Ohiun, ld'.. , Tetrcault, L. , and Fa:llils, A.: AieLlflpdopa and Il~drocldor,,'lkiazicle in PrimaTy 1nportcnsion: Controllccl Clinical'I'rial of 1)rug.s., un;n11' and in Con:bination. JAi.L\ ]:iG:~19-F2;i, 1963 518 6. \Yennl,erl,, Ohtcn, R. , Ai rman, F,. J. ,:';orthcutt, R. C. Grielt, P,. J. , and \t~allter,. A1':G.: Rcnali Tor:icit'yy of Oral C•holccystographic IMedia. JA11A, 1fiG'AG1-467, 196:1 7, Okun,lt.,, ilv:sscbl, I?.P.-and\'iil.son, AV„R.: l'r;eofDiar.onidev:ithTricli,lor- tnctl:iaziitn fur Ily;,crtensio;l, Arch ;)iter;i. Mcd 112:SF2-986, 1963 8, Olcun; Ii., Wilson, 11', R., and Gelfa ;d, \l.l).: The 11}perglycein ic Effect of ]il'polrn5icc Mu;s J:. Chron. Dis. 17:31-39, 190 9, CarJinpr, 11. I1. , SchpIlin;, J. , l;usscll, R. P. , Olaut, R, , and D:mis, S1!.: Thiazidc: :incd, . 1'lttalitntidicc Induced 7JyPerF'lycemim in H)Z,ertensive Pnticnts. JA1f.\ 191:535, 1965 10, Okun, R.: Princyples of Clini;cal DTt:e Lt^aLuation. Proc At'est. Pharm, Soc. 6:2(5-32; 19G5 11. \',?inters,' IR'. If., Levy, L. ,'1'h n•nnan, 1tC. , and Ul.1m, R.: Studies on the NIeLabolism nn:6D'istributiiornof Radfoactin•c Angnhetaminu. Proc. of At'est. Pltat'm. Soc. 9:1-3, 19'GG 12. 01ain:, IR, , Itoth, S. 1:. , Gntdon, A., and Niaxwcll, M. I1.: 'fhe Long Term 13ffecll\•cness of -Mrtli_,acl'op:c in Idy{icrtetnniun. Calif. 'lcd. 101:•1G-S0, 1906 13. i:lcum:ut., Q'. I2. ,;r,nd Cik crn, liL. ,.+nd' Ileller, It. J. : 'f'ho Rcnnl Rcgu:ation of SoJiGint Pota:aiu:^itl P:++iicnls nith: Chronic R'eenal Fai'luiro tuu] thc 1•:f-'cct of IDi:n-clie°,k en lLscE>:a•ration of tl;esc 1ons. Ann. New York Ac:cdeiaiy Sci. 130:,,:,1,_, o1, 190 201504612g

BI13i.1.OvRr1PiI1' Ronald O~:.ut 14. Sol;o1, A., 13as1:ner, AL l[, , Okwj, R. : A`cphrotic Spnd romeCansed'~ by Probenccid. JAMA 1J9; 13-:1, 1 G7 15. BaDtcs, D. , L•19 i^on, T. , Levy, L. , and O,..m, R'. : Thcllat'aboiic Pa~te of d-Amr'.1ctn~ :inc-iI SciLfat'c. Tleplmrrrncolooist 8:220, ItJGG 16. O1cun, R, ;. Diuretics-U.'.e and Al-rases The \icdi'cal Te]evisi.on 1Cetwo:'k, UC'L:1, Contcr for the I]calUh Scicnces. 19G7 519 17. Olnuo, R. andDllce;:•..,n, C. R.: Ren:zl Diseae Secondary to'SIetabo'.ic Disordcrs or Phvsiollo-,ic_l Dclilcicncy Statos. Calif. Mccl. 107;8-110, IGG7 18. Gerstcin,, i. R. , Olat:a, R. , Goaic::, 11. C. ; G•ilner, IL I. , Kieemznn, C. R, and ivia.; •c11, IL : Protc ncal', Useof:~1e11; ?.nr r.e 11ippuura+:e in Treatment of Urinary Tra~ct In:ection. J. Urol 10D;7G7, 1GS 19. •Siege1, ;,1. , filQison, T. , Silverman, A. C=~ , and Okun, R. ; Tissue Distri%"'ution of dll- ' jii-Aaupl,ctan.ii:e IICl in Tolc•z•miE and N.ontoleranUCats, Proc. yVest, Pharnvacoll. Soc. 11:90-0=1, 19G' 20. DIli:.~on, T. , Sic;;r1,.M,, Silvcrm,~ez, A,C., ami01•zm, Il.: CornpaT^.tive ~ Al(` 1'.ll. Cli C1- _1,~i11;lG.Yyd) J 1.iL ln 1C1(J.~nt'lnC1 CntS. Pi'ac. ?FcsU. Piu.r,r! aco] Soc. 11:75-77, 10Ga 21. SilVC.r]]R^Il, A. G. , a P]r] 0I;u?i, II(. , : Iso])ro(.omnP,l1 and D~oi)alline in tlle Treatnlent of h7elnirob:.mate Overdosa~goc in Cats. Proc. West. Pharmacol Soc. 11:91-98, 1968 22. Olcun, It'. :.l;edilcal Pain R'ol'icf. J. IIosp. Dei.t:1 Prsctice.11:32-36, 1063 23. Ol:urn, It. :, Use and ell'ase of Antib:o'_ics. J. ilcsp. Dental Practice 11:5.-G2, 1'.cJG3 f 24. Silvermrm, A.. G. , Wilncr, II. I. , tu:d Olaui, -11. : A Ccse Report of Gastro- intestinal L'lccdiin- FolloMan; the tisc of Tolr:zolu•:e.Tm: and App1. Pliarnn. 1G:31I8-320, 1970 .' 25. Silvcrm: n, A. G. ,NVilncr, Ii. I. , and Olam, R. , : A C:.se of Accidcntal Parenter^1 Injection of Povan. Tox and Appl. Pharrt. iG:7 r0-7-13, IJ70. , 26. Silverr..an, A,G., and Ol:.tn, R.: ii Loc:'.c at Son:v c•f the Common AdverseDru.- Reactions. J1. Il~ospa'.:LUDent;1 P:;ucLice , April p;,s-L0-5G. 27. Iilliso:, T., kc~ t, I,., Po1o;cr,.-J.. R.: Tl;^ \1etnLolic Faic of - 311-J'::;cOS1!inc in \i; ~~.L.i c,~c^;i JI. Ph^ra colio,,,' I;12L-1-ti~, 1970', 201504612;9

520 13I13LIOGIiAPITY 12ounld Oi:un 28. E111son,'1'., Snyder, F., Bo1Jer, J., and O'.cun, R.: Aictr:bolisrn of Orpltona.drlne Citu»te in Viun. J. Pl:nrm & E.;. '1•horr.p. 1'/6 (2);2or- 295, 1971 29. Ellison„'1'., Olnun, R,, Sil~'erm^t:, A. , sa:dSieg~el, ?`i.rSfetebolic rata of Annt,helurnino In tl,c Cat Dtarfn.g D(,velc):ncnt of Tolertcnce. Arch. Ir.t. PU1rmacc; :}°n 19@:135-149y 11070 30. Sil'r.cr:nsn, A. G. aud, O1a::x, R.: A Dou')1e BL',.d E`•clu.:tion of C::purlde in T.rc.:~ti..; Ilos~ITz_ll~zcd Pr.tYnnt^ Suj:arin;;frc,,x Loss of Sleep. J. Clln. Phsrm. 11 (Sj:215-2D, 1971 31. O1nen, I'1. : Tk:cr-apy of L':.rUlturc:t° Ocerdose. Gerlatrics 30:113, 1971. 32. Sllvermsa:, ~t. e.nd Okun, R.: Tl:o- Uce of an Al:?oat3 S~t.ppressant (Dicth}slproprto:r T?}ciczculorid'e) llu~r:n, Prc,n:,ncy. Cttrr. Thex-ap. Ros. 13: G48-653, Octobcr 1971 33. 8ilvcrm.,u, `.1. nnd' Oi.ua, ]i.: Ox} "'t.rac}telLuu-iitsiiatn In thi Provontion of Cnnoiid~.1 V'aGinit,9s, hnn. Ji. OL'GYl: 111 •".., Oc:oh r 1971 31. Olam; R.: CL'nic^1 Studier. In !,dretia Cortic:l Cc:rcinom.:: Current Studics. Proceediul;s of the Ci,anctF;cx:aiti Co:iercnce on Orlho~Parz'DDD. Ed. IBroder, L. E. and C[:rter S. h.- :;,alo^ci Ca:;icer Institute. Pgs70-79, Nov.1970. 35. Ro:<+s, J. F. , fle., it, 1V: L. , Wnhl, C. W. , O'a n, R. , Sh::piro, B. J. , Slaweon, P. 1?., and S!,ncl'Jman, P. S.: The ir_n€cccment of t!ie PtY:suicidal, Suicidal and Po:st suic!iii;l Pc2iont. liCld+ Corifcrotaco. Anusls of Int.: Llcd. 7L:441, Scptemher 1b"11 36. Paulus, I1.I•:., Sic2c1, M., E., Ol:uu, P., and Calabro, J.J.: Variations of 6; iwlm Conce:,tratoasznd IiaUf-TLlfe of Salbv.y1^to In Patientswith Rhcumnto:'d ArtLritis, Arthritis & R;:eum, tism 14:52'l, 1971 37. Okun, R. : Princ•iples of Treatmcrt: ')tctc3boiism Dnd' ExcrcCion of Toxic substances. Cl'ux. '1'o~rtcolo,ry ll.:]]etin °(5),:9-1•., 11971 38. Kaufman, J.J., Alnxv.c11, , Craven, J.1)., and Olaan; R,: UCLA ConScri•.ncc. Ilyp: rlmnsion- Primary and Sec:oadary.. Ann. Int. Mcd. 75:7G1- 770, 1971. 2015046130

521 BIBLIOGRAPIII Ronald O'::m II., and: Gates, T.:Acute Acncif:cm, Druption.Seconda;ry to MK-672. Arch Denu. I04:=E3, Nov. 1971, 40. harpman, II'. L., and O.nm; R. : The Plac.e of V3so ,i!'._!:or Drugs ia Periplron:l VascuiarDiscase. Ocriatri,csIIi PRESS 41. Champion, O.D. , Paulus, DI. L. , Bloui;:-.n, 1;'. , 0:z.un, 'L't. , Pen.r~on,. C. :d. ; Tl.el:ffect. crf !t~2,-Ar;n on 5': rttm Lidearc~°:Laci~n. C)d_. P1'.arnrF'fherap. IN PRESS 42. Oh1m, 1,.: TrcJment of S~~~a:,tive Dru; Overntose. CIi,.. Tox. IId PRESS

522 BfBLIOGR:1P lIY Ronald Okun Ch 1zCcrs in a ]3r,u{; Ol uta, R'.:IDevclop7icnt of tie+v llnu•,,. CLnptor in F.€scrati:~~lc of Pl.nrmncolo-; v Editor: J!o1n A. Iiesan. Publisher llocber Mcdicali Division, Il:urpcr C ltow; 19 69 , pp. 2) (1- 35. Vlrirm,icolr~; Olant,R.: 1'harnr..c~nlc,i;1 0[ PiaeeUos, Clanplcr in I'ssc,atitls of EclLfoc: A. ilt~~au~. Pubiishc:• Hocl;cr:,lcdicnl DiVision, Il:,rpcr C liaM' 1`iG9 pp 33--I2. Ohuny R.: Drul, Dc;icnr?cncc. Ch:pLCr in 1?s=cn?ials of ~>ti:lrmacolr,«v, Editor: Jolni A. 13'cvan. PtALNi iicr Ilucbcr `tc~l~ilcal lli~i~sion, 11at1~cr G I;o~,~' 1`lC'~ pp ~~J`p`)-11 Olaut, R. :Acute Drcg Poi ;oniug. Chapt.cr in Essetai:?.ls af Phru•mnvol=. Lditor: John A.Becan. PubLshcr 1ioJ)er "Mcdictl, Division, Llarpar tlKols; 1969 pp i3-~=. Ohun, R. ; Pslahu,:harinacc]or;ic A,;'c::~ts. Ch::pCCr in 1'sseatinls of PharmlcolowTd;for: Pub1isl;erlivebcr\tadicsl Divisiou, II;aJ:cr l• 11ow, 19G9, Pp 1q7..?12. 04.un, 1J.: Alcohs:l (i'tiranolland~'1'ePractl,,;lhirnann DSisuifid'e. ClrnpLOr in E::s_cntl; Is of P'ha~nnncolo:>) '. 1'.ditor: Jiol:m.r1. Bevan. 1'ublisher Hocber VICOlical Divi,aions HarpcrE• 1"ow; l`i~G'.) , pp 59'P-599. 012tni, ]R.: Antillilpid Agents. Clvpter in F.~ <:r.tials of 1'7 ^rm.lcolol~c Editor• John A. ]ievan. Ptd;lishco- 1{oebcr MCdical Divi;ioa,, ]farl~er f: I:b%c, 1969, }np 600-603. Ol;un, 1t.: Geneira~1 Principlcs of Clinical 1'h<armacole,;,}', and PsSichoph¢,rmacolorzr and Early Clinical 13l-lt,Ecalu:tions. Ch::p!crin P;-ircir,'c ~,'c~ of Ps~r.lo~hrarmaccl~ Editors: 11'.G,Clarlc and J. dol Ciatdicc, PublishcrAc;denic Press, N6W York, 1.e\+ York, 1970p, 3'1-39U. Okun, I(, : L'sC of Diurclics in the \dan: ; mont of Ilp:pcrtcnsion. Chaptor in Diuretics in the Atna~enai ut of Fluid RetcrGtens 1:cirlo~' 14cnrY(>.. ilcincmanoi, Al. D, , in i,loJ!crn 1r t;riinc.lt, A'oiu:1rc 7, Nu nhcr ", `..•rrch 1970, Publisher Ilocbcr 1lc:dical ~ G!1 Silvernaany A,G.,, and O;curo, ]fl.: 1lcpre;;:,nt 11rcil; C)ve:tlosc. ('h:eplcr in`('urtn,em% ~ I Imt .jr, ll`tiI ~ccti ,n Iir, In.,;c+ 7i'1-7i ;. Yi.blishar 11'.13. ~~.wnclcrsC'ompan}~ ~ PC.In. ',';VRnla. ~ W . N

BIBLIOGRAPIIY ChsCters in a Book Ronald Ol;un , 523 Silverman, A. G., and ol:un, R. : Depressant nrug Oveiylose. Ch.lpter in Current Thcrapv 1972, Sect'ion 15, pages 838-83G„ Publi:a:er t"'. B. Saur:dcrs Company, Philadelphia, .Pennsylvania

524 BdBLtOGIt.SPIIY Ron::ld O:uu ABS'I'RACTS', 1, SfegeT, ~1. , Aaon;;aai, r. , (1.-un, R., Cr:1:alDro, J. J. and Paulus, 11. I:. : The Self-Su~tinin„ ;mrvit°; 1 of Ii't,;h 5): ntntSolicyLat'e LevoUs inP::Cicnts M1H ltl:cur;^.^)icl :1rthriC'ur;. Artl'w:Us an& Rheumniti.:;m, p, 607, Dec.. 1000 2. Paulus, Il. t;, ,.ocd O;:u±:, 11. , and Cv,',a,wro, J. J. : G nanulocytc Itesponse toPrcdniigore.,..,' I"Giu^h^l::;o:ones ClinaP.es. 1'3:1;2,. 1~070. 3. Paul'us, PL 1•J. , Ol,on, R. , nncl Calabro, J, J:.: llepression of L'one Marrow GranulocyLC~ 1?cser;ms iln;;yVr_rmic Lui,:.s ErytLonnaCos'us PL1:). Arthritis and R9:Own:,'.i. m. 1'{a):"11,, May 10'i0 4. Patilus, 11. P:. ,\1or.; any E. S. , Siegel,, W, Oktmw P,; , and Pearson, C. 11: Per;istcncc n.r Sorann S:1'icy9nte Levra's inPatieuts mithChronic Rh.?wnatloid' Art!iritis. The P}sa:mtccologist 1&(: ); ?.92, Balli 191'0,. 5. Cloampioin. 5t , ASonj:vs, 1:. , Paulus, T'I. SarLis. ian, 1:. , Olcun, P,_, and Pcarsou, C. :Mctuf Coacairent _pirin (A=ic) .1cTmmis±rraSou on Soi,in]. Cor^entratic:;s of L.clomeilsocin (1). :+st!tmitis . Aifliritis °ililmiuiantism. 11:375, 1971 G'. Kai1in an, lI. L. ,vutd 0=.:an, R. :Vsisoel'ilating /+;;ents in the Preventiota of Acute T.IIoc.uiJial Ltfai:ct.ions. Cardib-Waseular llcscarch, 4: 182, Sept.19'70

525 B1I3LIOGRAP!IY Ronald Olcun Articlcs in Prc.)arntioii har})mvi, }iI.L., am(l Okiin, I?.: The Place of Vasodiln'.orl)rugs in Pcriphcral Vaseular 1)iscusc aniS O!au„R.:ArlliO~21i Vs P:ac-c1>o in the TreatmenL of C}audlicntion Kcrt, m. S,'I'arr, l,. W. , Frnn!.)in, S. , Gold, Olcuns R. , Diaxva-11, ",t~. and }deeman, C.: F...pr:~i<ncoo v~it13 t::a L-~ of ::^i /,ld'c:sUeroaie :bntai, onilst. in 3electrJ' IJa•pc~itcnsi~e Patic~;ts.