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PUnlac 1i[:nt.'r H GCriVIc:t_ 1'1/.t;rcnNolor:.,UC. ~c•fei ,1U51 ~ ~ IDJ10 Janathan E: _ kiaads, }f. D. hmerican C81Tcer SOciety, Inc. 2 19 Er, st 42nd Street Rew, York 10017 ]'orlcs, ncar Dr. F.hoads : _ ~ Pr.r~tc ~o: t,le hd1•e carefully reviewecl your rcquest th.1t I as Su*r(geon Ceneral establish a cc::::iittee of scientists to conc.uct a formal analysis of the Auerbach-t•r.:;;:.ond study. S)z,p<t}hetic a:. l:e are to f:lie reasons trtiicll have lec to t}iis request, t,e do not t':elieve sl:cii a foi,~al- .=e~,~._._. ~ ..._. _. 1rel=.iC:c' i6 ilC.ce: Gc'.ry in ordc'_I' to C.tc i~:'Si1 0le\'Ct)jali1_4y of the Stu"Cl}'. study in detail, a.ad, thGt- the ophorthnity corztiniies for revieay b). otl;rcr personc, anc)_uding scientiit.s ieprescl7ti_iiS the t~:bacco :industr)r. . I1Ltz-bCr of --ciel:tists outsiziC the Cove;::l,tent h.tvL also gone over the ~%uaa:::iG~;tt:L ]:rC'1 tnr' VetC:r?_ilP3 17:tGe1";,`tr.I1d t}mt a to the laborctorv :...aterial :rc Dr. John 11. L: r- t, c hr:;u'holozist iro`:~ the Ni1i.7_Ga:?aa' Cancer I:..:i..'lt.(2te LS'i(i Dr: t?ra,' sL~t~es _ ~. . _. . .:..~~. t.~ithlieJ_d. Amo:i- the qur_lifiieci Pe_-sont: uirio already n-lrldc thei•a- XC j>; coT2trFi):-y to 1'act 'th•'it sc:1'_elltifi::s 11a,Ve bCC;1 prevented f1:o.t ze`=ic~,1-nlg the ~aucrbach-};r caond etur,y orr t':4t u.:ta 1a4ve been iilk'estfg`tors l?llo have t^t:de \'«IuF,ble colltl'i}hlttio1:5 in tbejJ' rCSOective believe ijiineceseaiT. Dr£.:. t'.uerJac}1 ,:I1d 11'.:::moi'J6 i:.Ze quc.i.-'fied - There is 110 sc3.etzti.ffc study -,:,hi_cti casinot- benefit by the :-evietY off other scientists; it is the j.natit-uti.ona]., "j'llry" rev;cu l:•l:ich we :fields over ap:aciod of ra,ny years. T},cy h::ve c<.rried' on tiic, pres•ent -Btu4y uiider the i:,ost eminent r,l>onsorshil), ;:hat of your Socie'ty <+nd of: the Veteraais hdr:a.l:istration. T7le proce:lur.e& tlre.y h'-ave fo).1cw'e1 i9uvc been full_y descri_L:.Q in t31e lit:er3turc; they Il lye Tf ClI( C~ l9~lc?t" il )`)Ciir~:. ~.~-..,r,..,-.•. .»..~...._.,..~.,...vl.,,,,,..,.~ to be en ade-ow:te re~~ort c~f t}rc?i:~ z~tu ";., cu~ci ti~e~ 1)ave ou^ned Lhei~r ---.- ~,,.,.,,....~...r....,,~..,,. ~~~. . ,.,._~..~, ». a. ....~, ~- : dat:i to t}~e inst~cctto:~ of o..,ier sc:iencJj.:;t~.. l;e, do not lalow tYi3azt ilotc Ca il for be e):pc.cted of iAivesti ;atorr, especirlly tliosc t?i_th t]ie N ~ ):cpt~t~~tica~s O c:xcel3.eiice and probity enjoyed 1)3, })ru. I;uei-br~eh r.nd }'lasmmoiao3~. .- •

3onLtht~ti~ I:. I'~lror:dU, tS.A. :'cizr 2~ - : Dr. IScr~, har told ur~ iahr,t i:n lir_s no douht' but th;:t the rrol;res:;jvc chanl;c~i: 1~m tltir. t.ironcl~,~ir .~ir~ titsc:ucr3 of tl,e c:i~ rslt~ t~t:uc?icd ~~ere as Dr, l.ueLbacl, has dcscri.hcd thc~, aald thnt ~-;us~~, othcr eo~~d'itions ={,c.1116 vcrc e,!rly invasive squanous cell c<<cinoma in the bronchiPl i-i".ncs of vvo of the do~s. T.~f the qucstion at i_scue is whc~ther hunr,na- ciF,arette sr.:olce, then thc answer is yes, in the view of a Public ,, Iicalth Sci-v.'.-ce Pathologict with special cc-zpctencc in cancer. 1'h is lung canccrr has been discovered in tl:e luns;s of' do-,s exposed to pathoLo&ist;. who have reviewed the mutcrial. . -- icE also the view, we ti:uider.et4nd, of Da'. fe.:rler and of the other that ciS;arette st:,ot.i-ng causes lung cancer in }tumr,l beings. There was -.cnough evid'cncc si.x yer.rs a-o to causc the Sur-con General's AdvJ:sor.y Co~-,mittce on Se:ol:xng'r.nd l.ealth to co;ne to this conclusion, and this It 3_c not necessary to go to this study to support tlie conclusion -~-- - - - - -.~....a.....~.......... . . $Lll(~iy addr; onCG' nore e]emi`Tlt of cerra;*!,ilt" tJ a coacll3;io:1 \!hlc{l the evidence has been str.criStiiened in the ;}cars since, ' 7`he liucrhach-Net,,mon:3 .~.~.~ .~ ,~h02id's t:a-Clicai a11a tlez.l~:th c:unorit:ieS ;aready cons;ider certains r~ ~-= Tl1C' StUC3~' jS G1~~*j!Ol7SS r 5~~~,P~f'Cint O 1 C?S 'd ~7~UrSr~ "CO: . xt appears tC:' an l'_L•]pJrti=ni• n-1w research tool, an ul;?ltla! .''.-yn tC:1 on which Llodif.LCat1ons - rlcopJ.esta.c and non--neoplra,tic and f:Ltlie ::o=e, it ;,; y provide us ;c{ th provide us vith new 3•n` 1`;h~.t ? i,t0 CinSe-I ~l~ Cd }Tialm.iJntt1T}' char:Zes, 1)otll _~~e the ciF;?_rCi~:tC cG.`t be tested. and The I'u')llc jieratll Servicc: ha s the str:twt_=,~, .. responsibility of r.eportir.~-, -Ct t-Ln (`nc.c~:-C+c . -4',t regular 1i1 'CrVF.1S G n t:a ' 11:'_cnliifl co'_"t:ieCliucnces of c~-- ~ AIS G 1, r1te VS s~[ 1,r1teVS t11u i -world' . sczeirti f ic literature on s,n;o?ang "d iical:.h Z:nd evaluates i tth the htlp of esLinc_nt scientists, select-cc~ :_e:; both those outsiee the = Gorcrn.-neni: as 4rell as those in the Sc:~'j.ce itself, =,•The next revi e;a of the health consen,arences of -sr.:o?:in ;wilJ1 be rePortcld at the end of the calendar year. ihe A ucrh`ch-1'ii~:r.::.o,,-, 3 st udy' Frill be Si.ve n ' ` forr:.aZ,re:~ieti1 at this .t:ir.te •in its- Propc:r; contc;:t, ._w one of r~on}s resec=cn :• ntu:Iic:s shcddin& laS;ht 'on -a difficult ru1.: i,_portr_:.L' hcal th problem: I ' _ lt a.t: ~~ill n_'ot-'-e r.o ::-_ _:fccl cccrtain fro;i ve atrcnc'v l:rtol:? of `hc! s;t-iadv tl:z ~._ - - -~-_-_._... . ' - be arl co;rtritauvi o;i to our uilc .erstanciinS of the -sr..ol:i ng n.zd •.