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. t e} , NffRROR NEWS Los Angeles, California March 25, 1960 , .~ y THE GREENSBORO RECORD Greensboro, North Carolina March 25, 196Q I The New York Cardiovascular Conference was covered by local newspapers `and~ the press wires. ~4.3.;~. , NEW YORK, Mapch 25 tNr- Smoking may give you a lift byy triggering release of a perk-up• chemical deep in the brain, a British scientist sugeeated too- day- This chemical' may, in part, be responsible for the "pleas- ure of smoking,"'said Dr. J. H, Burn of Oxford University. Nicotine from tobacco smoke enters the bk:od stream and it could unloc'r- stores of ths chemical, c a l 1 e d norepine- phrinc. Bur., saidl in a talk pre- pared for a syrnpcsium partly sponsored by the Tobacco Inr dustry Resenrch Committee. Norepincp:irine is a chemical cousin to :ho hormone adren- alin which makc; your heart race wh^.n you'ne in 1`OBACCC7 MAY .. PERiC U P SMOKERS s -.. : . r~ ;. .,. ; ';NEW YORK, March 25 1M likely that the pleasure of Smoking may give you a lift smoking is in part derived by triggering release of a from the release of norPpine- perk-up chemieal deep in the phrine from its store in the brain; a Briuish scientist sug gesled t,,dav, ;;: brain by nicotine, the release This chemical mav, in part, he responsible for the "pleas- ure of, smoking." said' Dr. J. H. Burn of Oxford 1:!niver- sity. ,, 0„ Cheering Stuff ' Nicotine f r o m tobacco ~`e smoke enters t h e blood ~,. stream~ and it could unlock w stores of the chemical, ca.lledl ?"*~'~' norPpinephrine, Burn said. Burn explain?ri: '.' 1t seem.5 to me exl remely, . of cheerfulness and a sense of relief, from fatigue." Nicotine f r o m smoking also speeds up the heart, he said, probably by releasing gi~.irig an increased feelingJthis same chemiaal from spe ciaT storage units in the heart. ,. " In the heart, this action could aggravate the condi- tion in which heart rhythm >: is irregular, and it' could pro- :•.duce a more rapid heart beat. In sensitive persons, Burn 3aid, Burn explained: "It seems to me extremelyy likely that the pleasure of smoking is in part derived from the release of norepine- phrine from its store in the brain by nicotine, the release giving an increased feeling of cheerfulness and a sense of re- lief from fatigue." Norepinephrine a I s o has other actions in the body when unleashed' from~ its various storage p l a c e s by nicotine, Bur:a told the symposium on nicotine and smoking. Nicotine from smoking speeds up .the heart, he said, probably by releasing this same chemical from special storage units in the heart. This- same chemical, liber- ated by nicotine, may be re- sponsible for the sharp fall in skin temperatures caused by smoking cigarettes, he said. In one dramatic experiment, nic•,,t;ne was injected into a cat's tail and it made the cat's hair stand' on end. In an- otl+r r •~xperiment nicotine made the blood vcssels in a rabbit's ear constrict. Burn felt both actions were due to the liberation of nopine- phrine by nicotine. In the heart, this action could aggravate the condition in which heart rhythm~ is ir- regular, and it could produce a more rapid heart beat in sensitive persons, Burn said. The symposium, held by the New York Academy of Sci- ences, was in part' financed by funds from the Tobacco Indus- try Research Committee, a spokesman for the committee said. Perhaps half of the scientific reports made in the symposium had been supported at leas6 in part by funds from the to- bacco industry's com.mittee in- vestigating smoking and health, the spokesman added. Burn's work was not sup- ported by the committee's grants which has never sup- ported scientists outside of the United States, the spokesman explained.