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C -.- MD, Medical Newsmagazine November, 1960 VIROLOGY__ Cancer Clue Discovery by five Sloan-Kettering researchers of a virus associated with human cancer lends added weight to the growing evidence that viruses play , some role in human carcinogenesis. A unique property of the recently re- ported virus is that it produced a new disease in laboratory animals. Drs. Helene.. W.._ Toolan, _ .S",ilbert . Dalldorf, Marion Barclay, Satish Chandra and Alice E. Moore have found the virus in the tissues of pa- 710AN-RETTtRING INSTITUTE FOR,CANCER RESEARCN DEFORMED HAMSTER Virus from Cancer Patients ~- : .NE'~V YORK JQURNAL-AR'IERZCAN New York, New York October 27, 1960 , By BOB CUNSIDINE NOW THAT one automobile concern has come up with~ a guarantee on the life of its muffler and exhaust pipe It would seem to be In the wind for next year's models to go one step far- ther and etluip each new. model, with, a n.nia-r..z: filtef.: has not been detected in the carcinoma itself nor in the tissues of normal in- dividuals. Tissues of rats bearing trans- planted human cancers contain the virus; tissues of normal rodents do not. Inoculated' into newborn hamsters, the virus produces a deformity charac-' terized by small size, flattened foreface or microcephalic domed head, pro- truding eyes and tongue, absent or abnormal teeth and fragile bone struc- ture. Grown in human sera, tissue cul- tures from spleen cells of the infected hamsters contain the virus; no virus is found when the hamster cells are grown~ in horse or calf sera. Suggested is that horse or calf' sera may neu- tralize the virus. Particles thought to be the virus have been visualized in the electron microscope; they do not resemble the known animal tumor viruses. Infectiv- ity of the agent iss rapidly destroyed by ultraviolet radiation or heat, but not by prolonged cold. with cancer; to date, the virus That s not as far- fetched' as It sounds. A device named Mon- oxit, made by a couple of firms from Paw- "tueket, R. I., and Chi- cago, 'Fe,mbodies a unique combination of direct flame aft'er- f burner and catalytia converter In a compact, easy-to-install unit, no larger than three CONSIDINB Inches in its major dimension, which Is Ingeniously attached directly to the exhaust manifold under the hood of an automobile." `--It promises to take care of what certain cancer authorities believe Is one of the major causes of the rising Inci- dence of lung cancer in the U.S. If so, It, or something like it, should' be made as much a required part of a car as, let's say, brakes; In the Los Angeles area alone, the populace now breathes the gaseous -refuse and particles from the exhaust pipes of 2,600,000 cars. Will'we In time have mentholated filters on cars? Will the fumes become so well treated or toasted or twisted that she will, sigh, "blow some carbon monoxide my way?" * ~k *