Tobacco Documents Online

:'f t+ ;A, rB :: ~ ci~.~' ,.j y4ie .Y~, : FbR P.M RELRASE THURSiIAY,- OCTOBER 18, 1962 `4 ~~~??+ser' SIX-MAN P~SEARCH'TEA2d CITES V~IRIOUS FACTORS fi, ~ ~: ,: IN NEED OF STUDY IN LUNO CANCEEi CAUSATION ; . rrrr ,~ rr Y. s s _ s +a . +&` Washin ~,~ * gtoa The atmosphere of every cou~unity contains a range of s}{, r :~ FrYr -1`~t, cancer-causiing substances, which depend on liocal conditions, according to a ` s3x man scientific team in a report summarizeditoday in Tobacco and Health, r i z~ptx re~v..iew of research reports issued regularly by The T~o,tbacco'Ins~tyyi~tute, Inc, .Y~•.F~ ~`}~m M These~local conditions, tyh,e~seientists said, include indusCtrial r~tsY, y,~~P~~~; refi4 u t as y ~~ activities, traffia, climate, the i1amouat of sunshine anri genlogic conditions r They cited a need for further study of the reLatiive role and importance of suehfsctors (N t : h a ' t; o e e lead T uthor of the,article is Dr. Wilhelm C. Hueper,,head ~ ~of the Environmental Section, of the National Cancer Institute who shared in : , an award of $10,000 presented October 11 by the Unitedi Nations General Assembly ~F for outstanding scientific research work in the causes and control of r' ; x" "cancerous diseases "t) 1 v'~ F'r nn '# ,`~.C,, 1 l A a,..'" i'P ±`t They article, wh~.ch appeared in Archives of Pathology, a journal of the A~ America;~n Medical Association, discusses various factors under study, ineludi-ig 'g? ''R•~' f! trt,'.!-' fr yr.-s•- hr,~.UaT w?vS.:r+Y TST,w'1 °k at ?~,{ 1 "4 ~rtµ •-Flt + 4...r ~rCq~.}y'S; ~~~` their appraisal of the cigarette theory of lung cancer eausation ~ ~i °;lr' ~S ~~~~ h~ t n~~~,i r tiir3~~ a y G r k y~.7v wr, ~ e A. T r b ba~~y~ YrJ fi w L~3 ~ Six reasons why the cigarette theory is not "of' such ove .rhelming ~rV ls F Ymportance as alleged by many investigators" were outlined by the scientists ''^_ I~„i i 1?r~t rr ,}. ru'G~+N~'~i R rC '~Q;.t a4~i r_1 The increase in lung cancer frequency started in Europe uefore ;„+ t cigarette, smoking assumedi sigai°icant proportions ther .-„ ,~, '~~~,'~~''~ ~ I r Y~rJ ~ Fr~~ .Gx; r.{--:* t 91 r: s , rw . 43t~r~ } y R'~ :; 4J, ~2 The 'marked irregularity of lung cancer death rates, and sex ~4 f~ distribution, in different countries, different regions, andi different metropolitan areas of the same country - "w { '4i~~°~ s !~ , ,5 *S~.TI~'~r R.' ~yt., 1'~ti ~`.r~rS~11S}~r [S• 3 a 2he consisteat discrepancy between high urban Lung;~caneen rates against low rural rates observed in, several countries ". r~ M~'.~ ~k 1 !t ~ S yj ~ ijz a..:rF 5, r:, I,f.,:r=.v ir Yl \yr IC , /; 'Definite differences in rates between native andi immigrant whites ~ yty" ~4 ; ~~observed i N r . n ew South AfY•cad Ohi dit"Y ~ i~ Zealand,L, anioespe presumably ,.7w i~'' •JTf°2A ~ similar smoking habits.. r~ ~ Z,5 "Absence of s ppsitive statistical relation of ci arette smoki to ,~ ~~+°~~i~~ i cancers of the hands andi lips... " ~ ~~ ,,4 r~SSr r ~~1gM s~ 9 .-.Ys f. r._ .. . . . .- . , .._ .,.~.._.. . . . , t .. . - .. . ., k ...^. x_,,.. ..:-,.._ ...sr kt~l~' ~ " .~, ~,.•~- ~. ~,r'.~. ~~t +" TSE TOBACCO INSTITUTL INC " 808 17. th St N W:. Washb on 6 D C.- <,_ .... , . s , ~ y ~r- i L

The allegation that a higher lung cancer rate in England than the U.S. is due to "the English habit of smoking cigarettes down to a very small butt...i's based on uns~iitable and, therefore, incorrectly interpreted statistical data." The scientists said that "The far reaching contentions made in favor of' the cigarette theory of lung,cancer causation readirather convincingly as long as one either does not know or conveniently neglects to consider critically the indeed large and reliable amount of'evidence that is in disagreement with such concepts offered oftenias facts and proof." i,: While the scientists said it is "quite likely" that cigarette smoking plays a role, "'The voluminous reports on this subject published during,recent years give, n general,, scant consideration to the influences which nontobacco factors may have exerted on the causation andithe rise in freqluency of lung cancer, which, started before cigarette-smoking became generally popular-.":..!- 1~ Tobacco and Health, which summarizes published research relevant to tobacco use and health, includes a speciall report on the recent Eighth International Cancer Congress; also articles on the statistical correlation between marital status and disease, andion emotion and heart diseasie.. L •...: ..; . } r :• 1 t ..... , : . . .. , Briefs fromTpBACCb AND HEALTH, ~; Lung Cancer in Canada Near Peak? ~. #Al . . . . ...... .5' .. , ' y.. . . '. .... , ., (' .+~. _ •.~. !•L Canadian statis.tics indicate that male lur.g cs,ncer death rates may be , nearing a peak, reports an official of Canada's Department of'National Health , • . . . and Welfare. Dr. E.Wi.R. Best said "The rates show'some._tendency`toi-stabilizeT" and notedi that "This is consistent with the hypothssis that the male lung cancer ~ ~ r /f• .. . ~r . . ' . . . ...' - . 3 . ~ . L mortality rates are near a peak." Three scientists of'the U.S..Nationsl Cancer - •. _. 1 ...... ~C . . .. .. . .. .. ..r. _ .. . Institute had earlier reported a steady decline in the rate of.increase in lung.. . rd. J. .. . . . . cancer deaths in the U.S. since-1930: TYiey, predictedi that if the trend continues. lunig cancer deaths "will reach a peak among the white male population in the,,~ foreseeable future and then start to decline." CmVre.,. , r `,J.'7^ . ~ ;

Marriage, Divorce and Cancer according,to a new review by Dr. Joseph Berkson, chief medical statistician Statistical correlations show that annual death rates from lung cancer andiheart disease are higher among divorced persons thanthose who are married,n of the Mayo Clinic. The same correlation exists between marital status and most other diseases regardless of sex, he said. Dr. Berkson saidithis shows r the "fallacy" of relying on such, correlations to determine the significance of environmental factors in the causation of disease. Dr. Berkson said "Unless we understand the physical basis of the relation 0 ~ . . . ,;.; - a factor to disease in general,~ it i's hazardous to speculate: about its causal relation to a particular disease.`A Study of U.S. vital statistics indicates "a definite, but complex X'.S. -. Data Links Suicide, Cancer relationship" between death rates from suicide and from cancer, reports Dr. Lawrence LeShan, of the Institute of Applied Biology, of New York City. If'this link does exist, he said, "it-would, at the very least, markedly strengthen the case for the importance of psychological factors in cancer mortality." ; . .,,.., , . ;_ . . ._ .: _ . Viruses and Cancer ; ~More than 50`papersydiscussing viruses and cancer were presented at, ... _ ~. .. _ ~.~~~ Mouse Inheritance? the recent Eighth International Cancer Congress, reports T'obacco and Health. Four years ago at the 1958 Congress, there were only four papers on viruses.. . .. , . s ,. . _ -.- . . . . _ . . -- -- "' °" Two National Cancer Institute scientists report that Pri lun. ~Y ~~ •- , - cancer.may be the most frequent form of tumor foundlin wild house mice.. They n..;:1. bel3.eve the,,reason,lieq„iin,hereditary factors=.~n,_the mice.; T;- :. .. .. ; _ . - f g°- ~ ... .. .... . . . . .~. ..~~;i~ 1F; r ,e T-.,a , i.r_, E?s. ;. W ,.