Tobacco Documents Online

Stories on Dr. Eembtlrger'''e paper were noted in t'hese'two newspapers, and several papers receiving the Herald-Tribune news service. `- i THE WASHINGTON PO6 t' ~, 6 ~ 'UJashi'ngt'on,on, D.C. Apri''1 18. 1962 °ohacco Industry Ntudy 1+'i'nds Lancer Agent khe tii1at 'to itbp vitua ittTeo-'pvi-7ound th~ d t man coo1C meohenis ^th j-- a m l r Dr. Freddy Hmburger, med- N~'I' Y(~RI4 1~LD T RIBURE, muller„ and a research as- ioai researcher, of Boston, to Nev Yprk, New York sociate, Charles E; Buekler: ; The report of the confirma, ' Drs. Samuel Baron~ Robert M. tions was given' here today by Friedman and Robert I. Stlen- ' o productit that iriduce akin,yuce tu an~iv~TTprop-"erEles'fec ion without the help of the damage oceurs- tancers. in mice. were first discovered and' iti~ys n ommia l protective • Reporting the research were dhstry has oonfirmed long"chemioal laboratortea: 1 ehallbnged' re rts that cig Shterferon has been the sub••used' to tatmunize ht unans, feron~, Injeoted early after pO against smallpox. Then,, they known exposure;, may abort arette smoking can produce ject of Intensified research' rted:•th sto ed'that Im. virus diseases before body. ~' a`DOtit ensea can be mustered Zm-. In their research; the Be.' th'at virus., AELAN4IC CITY, April 1~portance of the findlhgs ~s'thesda investigators purposely Significaaoe of the feat' is .- Coatly. _ research finanaedithat thg blood product, Inter-{infected test rats with vac- that the results d'how that entieely by the tobacco in ¢eron, can be produced in .cinia, the live virus vaccine ehemically-concocted I n t e r- a y , e re attve y, By 'Nate Ha'selUne s beimgther_ body de,'mai;e it' ehemicall}. slow. buildltp ~ of antibodies to o e 1 painting of smoke conden- e Dnesence At the pnd of twe years, be- years, e aad• .'.. sates: perdodieally on thee skin. Causing anbstaneea 1n tobacco tween 45 per cent and 65 per "Butt yaureally can't mat'~e of mice canProdVtcen cancers;, tar has beenconflrmed by a new' c.ntof the Painted animals . tkila]umpJ'Dr: Hamburger aaid.- ~-but also . that . they produce studyy mvolvmg 1.000 mice. . • came dpwn ~~ with tumors, one- "We paidt a spot on ~~ the skinThe results showed pipe to- third of them canoers: The ev1= the size of, a postage stampi them to about the same de- baceo produced more tumors' dence appears to support tn ~ when you inhale eitarette` greeh d incidence as Dr: Wyn• than dgar tobaeea and ctgar to- detail I similar experiments ear- ' amoke. you spread' it over rt d d Homburger's experiments. - A.rLANTICCCIY: . mice twicee aweeka withh tar a man wu the equivalentof:a not only confirmed that the from one cigarette. pack of cigarettes a day, for 50 anar-h Th f 1959 by Dn Ernest Wynder, . tute;,a private research labora- evoke the cancers. If he took nowof'. Sloan-K~ettering. Insti- By Earl Ubell'toryfn Cambridge, Mass..They' Uttoaecountttie relatite: siustue for Cancer Res,earch. Science Editor tnvolved painting the skin of of'manandlmouse. the dose:fore a varietyof, sclenttstshad,re- by Dr. PTed.HOmburger, a well thetar. Dr. Homburgersatd, it!. ported.d they could notdupli• ~,+t & ~1~ ~ known, cancer researcher who teokabout'1U0 eigarettesto;, cate the results reported ia +~ K 1"lie~• beads the BIO-Research Insti- Produce the tar aufficient to of the Federation of A'mer- Tar & ~?LLl~~i / ican Societies for Espexi- (~; 1R with the field studies of human the males, although thediffer- mental Biology. - • , -being,whichaasociate eigarette'~ ence was not,more thanafewThe research was,instiWteds a smokdngwitheancer: per cent„Dr. Homburger said:, .Dr. Homburger saidj because ~ Cance~.~, The tests were carrriedi out If he ealeulated the dose of'f , • cnrt•ent 46th annual meeting a scientific session of the 'April 18 1~2 er.r a repo e • bacco morettutneigarettea:e ried outt ettlt, yearaago~ at thou+and+of.s saWaree feet of Neither report, of course, However, tumors teclinically m-W,ashingtonUniversity,. InSt. tissue .ln..the lung..Thatreducea' ptoves.that cigarette smoking~cludeg both bentin' and malig- Louis, bythelatcDr., Evsrts the local dose enormously." _- eauses lungeaneer in humans nant; growths. When only can- ptaham, hmiself a victim~ of ' Pipe and Clgar---tliough they lend some sup•. cers were counted, all! the to lung cancer, and' Dr. Ernest 2f thePtpe,and cigar tobseooa porYto.thatclaim:-baceosproducedaboutttieaame Wynder,.now at the 6loan-producedmore.tumors,whyare • Homburgerr reported todaynumbery ef:ancerous anlmalE: KetteringInstaute:Dr,. Wynder theyassociateN with lessean-- ~ can- that . h'eused three kinds . of 20 perr cent of I each group of has since followed up this study oer inthestatisticaln studiess of tobacco„ cig$retted pipeand! ~te. inattempting. to isolate thee man? '14m,research~reportedyester- Dr. Homburger aatfll it eigacAil weree prepared for day.fcrthefirsttime, had been part't°i'tlarcancer-eausmgagent! ,mghtbe' that the cigar and smokdngg in cigarette form oo i fl„anced byy a three-year aranG 7emrrrature. I~portant P:De smok- is,so. heav,ythat it a mectianicall smoker. Their of t86•250.fromthe Tobacco In. IIp to tliiseurrenttest; other is difficult't to inhale it: into the smokeeondensates(tars) were duatry. Research Committee. researchers havee had dimculty lungs:. Thishas; been the rea- separatelyeollected: ; Dr,, Cl'arence. CookeLbttle, tn igetting the same consistent son given by other researcfers. Surprisingly,, there was -ehairmann off thee industryeffeetawhich.Dr. Wynderob- Dr..HOmburger said.he.un, :very little difference between ;group's Seienpfic Advisory tained: Dr. Homburger,reported dertook the study for'thc To- -the tobaccoss and the number Board, said his board never had that the temperature at which baccoCommtttee. underare- of'.tumorsthat developedl This-any4outit:thattobaceo tarscon- the tobacco is smoked is critiealV fully eontrolled, circumstaneea. contrasts to the' Cancer So- talned~.cancer-p,rovokers•: known Too get histar, Dr., Hom- For example, he paintedsomed ciety study: which found that sctemiflcally as carcinogens. burger asked the Acoustiea of'the mice with a solution of only cigarette smokers greatly.- Mice.Yes; Men-T. Paper Co., ofOlihIndustries, acetone: the solvent ln which, outnumb'ered non-smokers in Reached by telephone at: his's to~ use aa special' cigarette- the tar was dissolvedifor, thelung.cancer incidence:, Pipe. -home inBar.Harbor„Me..,Dr.. amoking: tar-cotleeting ma• othermice, These acetone- and cigar smokerss showed Littlee was ~asked: chine. This machine smoked. Painted mice . developed no tu- only a slight inereasee over "Would you.say this research, citcarette. Pipee and cigar tobac- mors. A'lso• he, didn't know-non-smokers: Provesthattobaccotarcontainsi cas, fabricated asidentieal whichtarwaswhich;they'were - The newest research, still earcinogens?" cigarettes. The temperature coded by number and the code underway' after two years. "For,mice?^xas1,600degrees Fahrenheit. was:kept lAckedlupbythe Na- was. financed by a three-year "Ye+1"the sametemperaturee used by tionalilnstitutcs.of.Health.The grant of. E28,750 a, yearfrom"Absolutelyyesll Without Dr. Wynder. Other researeherscigarette-smoktng machinevas ~~ theTobacco. IndustryRe- Westion'!" had employedl lowertempera, approved bytheTobaceoCom- seareh Committee. However. Dr. Little was more tures. mittee as we11J, Four medical investigators oharywhenitcame,toextending Dn Homburger said the What Ls the Tobacco Com• fromthe.Nataor.ai!.Institutes of thrdindings to man. Hcsaid~he higher'temperature was the.onee mltteee going to cb . now? Dr. `Hcalttr,Beth2sda. Md., report- wanted to study thee findings, he believed existed in theburn-Lfttk said It,wlq study, the re• presentedlto thcannuallmeeting tngtnd of cigarettesas.smoked' port very' wrefully' and eon- 'ed thatt a normally weak anti-' of the. Federation of' American by human beings. tinue to support research In the. -yiral, component' of blood ha:Societiea for Ezperimental. 81+ Female,m3ce ,.2iad consistently fle', , . - _alogy, and tryy too square. them hiRher numbers oCcaneers than.~ "