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Philip Morris

Cancer Produced in Mice by Smog Breath Quickness Is Caused in Guinea Pigs, Study Finds

Date: 19620417/P
Length: 1 page
1003537668
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Author
Sullivan, W.
Area
JOHN-WARE,JUDY/SHB FILE ROOM
Type
NEWS, NEWSPAPER ARTICLE
Site
R22
Request
Stmn/R1-037
Named Organization
Division of Air Pollution
US Public Health Service
Named Person
Kotin, P.
Prindle, R.A.
Document File
1003537539/1003537961/620000 TI and TIRC Editorial Comments Informational Memorandum Releases
Litigation
Stmn/Produced
Author (Organization)
Ny Times
Master ID
1003537539/7961

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EXTR, EXTRA
Date Loaded
24 May 1999
UCSF Legacy ID
wnb91a00

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Page 1: wnb91a00
C ',1rtiath Qulcknsss IsCausNd ::;In1Cuinea Pip, Study iFinds ;-' Dy WALTER SL7d.IVATf : lVnog, has produced I cancer In This was mixed' with strln- tbelw and!pulckaeas of breath In gastly' purlfied Siz to provide, ~ y~ "aaog" with no foreign sub- Thta waa, reportedi yesterday stances apart from the exhaust by Dr. Richard A: Prlhdle, meda p~,~ b~ bat~hedoia larti- kal director of the Division of, ~~ .~g~ Other gui6ea .. ~~Air ~ PAllution . 'of the ~ tfnited'' pip ~~ were ; given ~~ a ~ similar ~~ at• . ftates Pubdt Health Service. 'raoaphere to breathe, without h t. orted on studies oar-j~ to such lig Sa re p : >eMd out In recent years at a, -"" 'mpaitment of lung ttme- ~~~e ~p0rted was a~ ' aumber of'l>.boratories 1n an ef, tnarkedly more severa, where Lort to pin down 1 the health ef. t,hefumes bad' been exposed to fects of Increasing air pollution artificial sunlight. The evidence In our dtka He noted that the therefqre suggests, he said, that lung cancer rate had doubled In stinligtit alters smog to produce each of the past few decades. more I:rttating acids. The 1m- pdrment ended when the smogThe tndllettoe of'emphyae&a, was replaced by fresh aie, if' ba added, bas riYen about'seven- the exposure was for only' told In the, past decade-lblk 1d 'two, to four hours. a disease marked by enlarge- Dr. Prindle spoke to the mmt'.of':the.lungs and thetroom• Jo1nt Annual . Conferencee on i . . e1t ~brculoeis and other Respira- p~mta, He stressed that ' tory Diseases,.held at,the Hotel - pollution waa not aecessarily tbe Statler Hilton under, the aus- ~ oQalyfactor involved, and . he pieea" of various organtzatlons ~. cited ~ the evidence ~ put forth to ~. ooncerced with ~ tuberculosis.~ He _ aupporta~linkbetween~smoking~ noted that~vehicle~,exhaust was~~. betng rob'1 othens lem one ~ , p , y :. aad cancer of the lungs. . htdustrlal smoke and the chfin, ;, To,Bepost'mLahauatAct neys of'pdvate homw. A full report on research by the Publlc. Health Serviceinthis aroa 1L to be presented to Caagress.inJune,:in.conformity. . _with the Motor. Vebide !F.xhaust'. Act of 1980:. Dr. Prindle cited i the . work of„ Dr. Paul~ Kotin in ~. Los, . Angeles '' In wtiich.his group infeoted mtce with influenza.virus. Those who . survived had a slightly higher . cnncer rate,than , mice , that: had not been infected with the virus. However, those of the : fluu s•.u- 4ivora later exposed to an arti, fidal smog:.of ozonfzed!gasollne. -developed' cancer atat rate many times higher than the . others: He said' this appeared to be the first sucW production of. . .hmgcaneer 1n animals by smog. He noted that thesexratio.wastwenty-n1nemales to ~ nine - fe males, which, he sai4 Is simllar to the lung cancer ratio in hui manbeings.This.n he asserted,, suggests thatthepTeponderance of'the.dlsease.m men is tnt.aresulG of, smoking or occupation. . Laboratory studies of the ef- fect of, automobile exhaust onguInea pigs suggeat.that,"sun+ burntng"' of smog plays an . im M , tant role In making it. in+ous;. Dr. Pttndle said. He described studies that have been tarrled out, usingautomobntg exhaust from a Public HealthService vehtde., CHRONDCL.E All,entovn, Pa. Apri1 21, 1962 ' sbvas sE'NID TRIBUNE South B!end, Inditula N(9;y 11, 1962 Overeatirng 'I"hreat T © p'a Lung Cancer LONIDt)NI (UPi) - Over-eating kills more persona in younger age ,groups than lung cancer, a Brit. lab dbctorJayp: , Dr. A'4n , Akeroyd reported in the British',Medical Journal thatt persons who give up smoking us- ually increase their intake of food. He said that the necent royal eollega of physicians report link- ing, cigarette smoking with lung cancer failed t'Tflat the heavyy smoker as a personality. "lbis type of person ustnlly is tense, anxious, likely to produce a duodenal ulaer, hypertension or coronary thrombosis." he aaid. - Oral Graetioatioa.. "Cigarette amoking is a kind of oral gratification relieving deep uncottscious needs. Following the widespread scare of developing carcinoma of ehe lung from smok- ing, one wonders what will hap; pen to the heavy smoker who mntinues to smoke and Iwith each ciganettefeels frightened and guil- ty; or to the smoker who, gives up smoking and l loses his oral gntifcation.. •.Normally, a: person giving,'up smoking , puts on n:ight because be changeshis gratification from, stnoking to . eating, overtiting . is ; a much more common costnbu- taryfactor todeathina much~ earlier age.group.thanlang can,cer. Smoking I isn't On! yCancer Cause ~ e^lneid ce of emphysema, Th' marked by enlargement of the lungs and t'heir, components, has risen about sevenfold inithe past decade. Ascribing this to smog in cities, Dr: Richard,A. Prindle; medical dtrector of Air Pollu- tton of the U.S. Public Health Service, said that'smog produced!cancer'inmice and, It is more severe when the smog ia exposed to sunlight. Dr. Prindle stressed,that air, pollu- tion Is not necessarily the onlq factor Involved in cancer productlon, citing evitience to support a link between smoking andicancer of'the Itings. How- ever, since the incidence of smog-pro- voked' cancer in mice was 29 males to 9 females, the same ratio as lung oan• cer ratio In human beings, he suggest: edi that the preponderance of the dis- ease in men is not alone the result'of smoking or occupation. Research is slowly revealing, th factors that produce cancer. Eventual 1y, when ail,are identified, It may be , found that several play a part' in this)~, fatal disease.

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