Tobacco Documents Online

NEW YORK TIMES' New York, New York April 17, 1962' 100"C10 ( CANCER PRODUCED IN MICE BY SM4G, Breath Quickness Is Caused ..In Guinea Pigs, Study Finds The incidence of emphysema, be added, has risen about seven- fold in the past decade. This is a disease marked by enlarge- ment of the lungs and their com- ponents. He stressed that air pollution was not necessarily the only factor involved, and he cited the evidence put forth t'o support a link between smoking and cancer of the lungs. To Report on Exhaust Act ; By WALTER SULLIVAN Smog has produced cancer in This was mixed with strin- ,knlce and quickness of breath in gently purified air to provide guinea pigs. "smog" with no foreign sub- This was. reported yesterday stances apart from the exhaust. by Dr. Richard A. Prindle, med* Part of this was piped to guinea pigs after being bathed in arti- fcal director of the Divisi= of; ficlal sunlighG. Other guinea Air Pollution 'of the United'I pigs were given a similar at- States Pubdc Health Service. i mosphere to breathe, without He reported on studies car-. exposure to such light. ried out in recent years at a•- The impairment of lung func- nwnber of laboratories in an ef- Hon Dr. Prtndle reported,, was fort to pin down the health ef• markedly more severe where the fumes had been exposed to fects of increasing air pollution artificial sunlight. The evidence in our cities. He noted that the thereYqre suggests, he said, that lung cancer rate had doubled in sunlight alters smog to produce each of the past few decadea.more irritat'ing acids. The im- airmnt ded h th e w e A full report on research by the Public Health Service in this area is to be presented to Congress in June, in conformity .with the Motor Vehicle Exhaust Act of 1960. Dr. Prin?!e cited the work of, Dr. Paul Kotin~ In Los Angeles in which his group infected mice with~ intluenza virus. Those who survi ved had a slightly higher caneer rate than mice that hadt ne} been infected with; the virus. However. those of the flu s:ar- vivors later exposei to an arti- ficial smog of ozonized: gasoline developed cancer at a rate many times higher than the others. He said'~ this appeared to be the first such production of lung cancer in animals by smog. He noted that the sex ratio was twenty-nine males to nine fe- males, which, he said, is similar to the lung cancer ratio 1n hu- man beings. This, he asserted, suggests that the preponderance of the disease in men is not a result of smoking or occupation. ! Laboratory studies of the ef- !` fect of automobile exhaust on auinea pigs suggest that "sun- burning"' of smog plays an im- rtant role in making it in- urious, Dr. Prindle said. He described studiesthaG have been carried out, using automobile exhaust from a Public Health Service vehicle. p en n e smog was replaced by fresh air, if the exposure was for only two to four hours. Dr. Prindle spoke to the Joint Annual Conference on Tubrculosis and other Respira- tory Diseases, held at the Hotel Statler Hilton under the aus- pices of various organizations concerned with tuberculosis. He noted that vehicle exhaust was only one problem, others being fndustrialsmoke and the chim- . neys of private homnq CHRONICLE' Allentown, Pa:. Api~il 2l, 19Fx^ SOUTH BEND TRIBUNE South Bend, Indiana May 11, 1962 /o0 Overeating ~vy Threat T ®p s yy~ . Lung Cancer LONDON (UPI) - Over-eating kills more persons in younger age .groups thait lung cancer, a Brit- ish doctor4ays. Dr. Alan Akeroyd reported in the British Medical Journal that persons who give up smoking us- ually increase their intake of food. He said that' the recent royal college of physicians report link- ing cigarette smoking with lung cancer failed to'Treat the heavy smoker as a personality. "This type of persom usually, is tense, anxious, likely to produce a duodenal ulcer, hypertension or coronary thrombosis," he said. Oral Gratification. "Cigarette smoking is a kind of orali gratification relieving deep unconscious needs. Following the widespread scare of developing carcinoma of the lung from smok- ing, one wonders what will hap- pen to the heavy smoker who continues to smoke and with each cigarette feels frightened and guil- ty;, or to the smoker who gives up smoking and loses his oral ,gratification. "Normally, a person giving 'up smoking puts on weight because he changes his gratification from smoking to eating. Over-eating is a much more common contribu- tary factor to death in a much earlier age group than lung can, cer. Smoking Isn't Only Cancer'Cause 10.-'o .. .. ,.. The incid ce of emphysema, marked by enlargement of the lungs and their components, has risen about sevenfold in the past decade. Ascribing this to smog in cities, Dr. Richard A. Prindle; medical director of Air Pollu- tion of the U.S: Public Health Service, said that smog produced cancer in mice and it Is more severe when the smog is exposed to sunlight. Dr. Prindle stressed that air pollu- tion Is not necessarily the only factor involved in cancer productlon, citing evidence to support a link between smoking and cancer of the lungs. How- ever, since the incidence of smog-pro- voked cancer in mice was 29 males to 9 females, the same ratio as lung can- cer ratio in human beings, he suggest- ed that the preponderance of the dis- ease in men~is not alone the result of smoking or occupatiom Research Is slowly revealing th factors that produce cancer. Eventual ly, when all are identified, it may be found that several play a part in this ) fatal disease.