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Patents Cetus Corporation is active in obtaining-patent protection for its significance. In many of these cases, discretion precludes specific binant DNA discoveries, and specific processes of definite industrial developments, where appropriate. Coverage is expected in a wide number of technological areas, including cloning techniques, fusion and recom- description ~ J ' . a,.;,) ... . e~ . . •, In the area of recombinant DNA there has been much recent discussion of dictates dealing with particular companies. implying that involvement in the commercialization of this technology the confused patent scene. Many outlandish assertions are being made, actively challenge the validity of certain patents,`if issued, when it - Cetus Corporation firmly believes such claims to be",ridiculous, and will private profit. Jc~ ` o~ O4~ certain arrangements in which public funds were`used as leverage for seems appropriate to do so. We may also challenge;the legitimacy of mental technology without which~there couid not have been accomplished of one of its employees and his co=w'orkers,.who developed the funda- More to the point, Cetus has applied.for 'patent protection on the work and by the Gilbert group of rat insuliri. the successful expression in bacteria by the Boyer group of somatostatin, laboratory in~the world, will probably be even more important in the long run. G ZY ,~ a,©.,~{,~ a~~. • . .c,~., ~a ~w .. . . . which, to our knowledge, we are building more quickly than any private capability, reflected in'facilities, know-how, and in-house skills, believe we have a broadly-based technological lead, and intend to main- tain it. Patents will_be part of the picture, but only part. Overall : There is much excitement ahead, and many new discoveries waiting to be made. A number ofthemwill_'doubtless be patented, some by Cetus. We presently carrying this~work forward in Cetus laboratories). V Further, the patent for the'chemicalymethods used by the Boyer group to construct synthetic genes•lis held-by Dr. Saran A. Narang, a member of the Cetus Board of Scientific Advisors, and co-workers (one of whom is

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