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NAME: ADDRESS: SOCIAL SECURITY DATE & PLACE OF BIRTH: CITIZENSHIP:. MARITAL STATUS: EDUCATION: 1973-1976 1976 1976-1978 1978 1981-1986 1986- pres. RESEARCH POSITIONS: 1978-1980 AWARDS/SOCIETIE~ 1986 1986-pres. CURRICULUM VITAE Michal Baniyash 251 Rollins Avenue Rockville, N~D 28052 (wk) (301) 496-5216/(hm) (301) 770-4704 216-I 1-8540 04102/54 Haifa, Israel Israel Single Biology studied at Tel-Aviv University B.S. in Biology Studied for the M.S. degree in Microbiology, Tel-Aviv University, under the supervision of Professor I.P. Witz Thesis Topic: "Immunological and Biological Properties of the Variants FI and FI0 in Mouse BI6 Melanoma Model" M.S. in Microbiology, with distinction Ph.D. Student at the Department of Chemical Immunology, Weizmann Institute of Science, under the supervision of Dr. Z. Eshhar Thesis Topic: "Immunological Characterization of the Interaction Between Immunoglobuline E and its Receptor" Post doctoral studies at the Cell Biology and Metabolism Branch, National Institutes of Health, Bethesda, under the supervision of Dr. R.D. Klausner Primary Research Topic: "Structure and Function of the T Cell Antigen Receptor" Research assistant at the Department of Microbiology, Tei-Aviv University Distinction Prize for Ph.D. students of the Feinberg Graduate School of the Weizmann Institute of Science Member, American Association of Immunologists 40000304

LIST OF PUBLICATIONS Baniyash, M., Netanel, T., and Witz, I.P.: Differences in cell density associated with differences in lung-colonizing ability of B16 melanoma cells. Cancer Res. 41: 433, 1981. Baniyash, M., Smorodiusky, I4.1., Yaakuboviez, M., and Witz, I.P: Serologieally- detectable MHC and tumor associated antigens on BI6 melanoma variants and humeral immunity in mice bearing these tumors. J. lmmunol. 129: 1318, 1982. 3. Baniyash, M., Waks, T., and Eshhar, Z.: Suppression of lgE production by anti-isotypie antibodies. Israel J. Med. Sei., 1982. o Ballin, A., Aid join, M., Baniyash, M., Boiehis, H., Barzilay, Z., Gal, R., and Witz, I.P.: The effect of Lithium Chloride in tumor appearance and survival of melanoma bearing mice. Br. J. Cancer 48:83, 1983. Baniyash, M., and Eshhar, Z.: Monoelonal antibodies to murine IgE inhibit IgB binding to rat basophilic leukemia cells. Eur. J. Immunoi. 14:799, 1984. o Baniyash, M., Eshhar, Z., and Rivnay, B.: Interrelation between antigenic sites on lgE recognized by monoelonal anti-IgE antibodies and the mast cell receptor. L Immunol. 136:588, 1986. Baniyash, M., Alkalay, I., and Eshhar, Z.: Monoclonal antibodies specific to the alpha- chain of mast ceils Fe-opsilon-R block lgE binding and trigger histamine release. Immunol. 138:2999, 1987. Baniyash, M., and Eshhar, Z.: Anti-anti-IgE idiotypie antibodies mim|e lgE in its binding to the Fe-epsilon receptor. Eur. J. Immunol. 17:1337-1341, 1987. o Baniyash, M., Eshhar, Z., and Khery, M.: Anti-IgE monoelonal antibodies directed at the Fe-epsilon-reeeptor binding site. Mol. lmmunol. 25:705-711, 1988. 10. Weissman, A.M., Baniyazh, M., Hou, D., Samelson, L.E., Burgess, W.H., and Klausner, R.D.: Molecular cloning of the zeta chain of the T cell antigen receptor. Science 239:1018-1021, 1988. 11. Baniyash, M., Gareia-Morales, P., Bonifacino, J,S., Samelson, L.E., and Klausner, R.D.: Disulfide linkage of the zeta and eta chains of the T cell receptor:. Possible identification of two structural classes of receptors. J. Biol. Chem. 263:9874-9878, 1988. 12. Baniyash, M., Garcia-Morales, P., Luong, E., Samelson, L.E., and Klausner, R.D.: The T cell antigen receptor zeta chain is tyrosine phosphorylated upon activation. J. Biol. Chem. 263:18225-18230, 1988. 13. Sharon, M., Gnarra, J.R., Baniyash, M., and Leonard, W.J.: Possible association between IL2 receptors and class I HLA molecules on T cells. J. tmmunol. 141:3512-3515, 1988. 14. Klausner, R.D., Weissman, A.M., Baniyash, M., Bonifacino, J.S. and Samelson, L.E. The role of tho ~" chain in expression, structure and function of the T cell receptor. In "Mechanisms of Lymphocyte Aetlvation and Immunoregulation" (S. Gupta, ed.) Plenum Publishing Co., New York, NY, Vol. 2, in press, 1989. 40000305

15. Baniyash, M., Hsu, V.W., Seldin, M.I=., and Klausner, R.D. The isolation and characterization of tho routine T cell antigen receptor zeta chain gene. Submitted to J. Biol. Chem., in press, 1989. 40000308