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THE INTERNATIONAL CENTER FOR A SCIENTIFIC ECOLOGY The Center has been created at the beginning of 1993 under the French law for no~-profit ocgani?.ations, The pur~se ~s to answer the request from a number of the Heidelberg Appeal signatories in view to extend its impact in examining actual issues the scientific community is confronted with. The purpose of the Center is expressed in the by-laws : "The purpose of the Assodarion is to promote and facilitate exchange of sdentific ~<nowledge. based On sdentif'~c da~a. regarding the protectiOn of mankind, other living species, sites and the resources of the planet. The Association thus proposes lo provide the most relevant sdentiFtc laces to ~he authorizes responsible for developing enviro~menta! protection policies, to the Society whfdr~ under the principle of transpamnOjo is called upon to express i~s poioc of view. as w~ll as to all sodo-e¢onomical partn~s who want to contribute in both the conservation of the Earth and the ~ong-term deve!oprnent of its populations." The Board of the Center includes in parbcular: - Mr Pierre Joly, President of the Association Frar~aise pour la Recherche Th~rapeutique : former President of the International Federation of Pharmaceutical Manufacturers Association ; o Mr Constant Burg. honorary rnern~e; of the State Council honorary managing director of INSERM : President of the Institut Cude: - Mr Gilbert Rutman. chief mining engineer: President of the Conseil National des lngdnt~rs et des Scientifiques de France : - ~rof. $. Fred Singer, Doctor of Physical Sden.ce ; President of the Science & Environmental Poticy Project : former Director Weather Satellite Program : Dean of the School of Environmental Sciences. University of Miami : Deputy Assistant Administrator of US Environmental Protection Ageno~ (EPA) : - Mr Gary Nash. Secretary General of the International Council on Metals and the Environment (IEME) : former Director General in the Canada Department of Energy. Mines and Resources - Dr. Michel Salomon, coordinator of the Heidelberg Appeal former science jouma|ist : m~gazi~e editor. International Center for a Scientific Ecology Centre International pour une Ecologie Scientifique Is the concept of linear relationship between dose and effect still a .valid model for assessing risk related to low doses of carcinogens ? An international scientific seminar organized by the International Center for a Scientific Ecology May 10, 1993 - Paris (France) (Hilton Hotel. 18. Avenue de SuffTen. 7~)t5 Paris) Under the patronage of the following Associations : • The Science and EnVlronment~l Policy Project • Enb-eprises pour I'Envlronnement Consell National des Ing~nleurs et Sclentlflques de France The Seminar devoted to the Ilne~l" dose/mspoctse relationship Is the fl~t event Initiated by the International Center for a Scientific Eco|og~. Int~rnatlonal Center for a Sdentlflc Ecolooj 10, avenue de Messlne. 75008 Paris. F~ance Phone : 33 1 45 62 20 03, Fax : 33 1 42 89 O0 59 0 BATCo document for Mayo Clinic 27 March 2002

AGENDA Mon(~J' M~ 10o 835/8~ ~m. • ~e ~ by ~ ~, ~n of ~ Initial 10.~/I0.~ a.m. • ~e ~la~ amendment con~c~ ~ the ~edcan ~ulaU~. 10.20/10~ a.m. * ~e b~ak. IO.~IN~ ~ ~ ~i~: P~i~s and ~. (~ ~ief D~. of R~a~ In~. S~n-~ng, ~). (Ep~iologi~. and L~ ~., ~on, - ~e ~ ~ ~inHne a~ de~ p~ Coundl of Wn~ Manu~. ~. Belgium). -~e (Ph.D., m~l~i~, of mo~i~ - ~ (Un~ o~ Pi~d~ ). Moon/1Z30 p.m. 17_.~)/2 p~n. 213 p.m. 3/4,30 p,m. 430/5 p.m. 5/6 p.m. End of Seminar. 6/7 p.m. • Special meeting with intemaUonal scientific press for Q/A and inten~ws, Participants to the sdentlflc Panel invitations have been sent to a n,mber of distinguished IntemaUenal scientists. We expect twenty to thirty sdentist~ to attend. Audience A number of personalities from indust~ and admlnlsttations W~II attend the Seminar as observe~ Their flnandal ¢on~butione making the meeting possible. Organization The Seminar is organised by the International Center for a Scientific Ecology (see Introductlon to ~ Center in eov~r page). The scientific w~rk is organlsed by.Dr Michel Selomon. Coordinator of the Heidelberg Appeal. 11-anslatlon lectures and comments may be eithe~ In English or FrendL Simultaneous eranslation will be provided in both languages thmughout the Seminar. Press Conference International scientificJoumalkts are asked to register if they wish to attend the sessions A press conference will be held by the members of the sclenUlic panel at 6 p.m. on May 10. 1993. RATC~n dnm=m~.nf f~lr M~Ivn Clinin ~7 M~rch ~f~l:)