Mayo Clinic
Subject: Effect of Passive Smoking on Respiratory Function - F. Kauffmann and S. Perdrizet Eur. Journal Resp. Dis. 62 (Supp. 113)1981
Abstract
Comments on Kauffmann study on effect of ETS on respiratory function of nonsmokers. Compares to findings of previous White-Froeb study, noting that neither claims an increased incidence of respiratory disease or symptoms. Reports that Kauffmann study demonstrated an effect of ETS on FEF25-75% parameter [see Comments] only on data standardized for educational levels of male subjects, implying that FEF25-75% values are influenced by socioeconomic factors. Criticizes Kauffmann study for failing to account for confounders (occupational and household pollution, presence of pulmonary disease, wife's educational level), and for technical flaws in data. Concludes that "because of the numerous shortcomings in this study, the conclusions of the authors are not warranted."
Fields
- Notes
FEF 25% - 75% (Forced Expiratory Flow Rate); spirometry parameter; gives an indication of what is happening in the lower airways; can act as an early warning sign of disease (see http://www.priory.com/med/spiromet.htm#Q.%20What%20does%20spirometry%20measure?)
- Type
- Memorandum
- Company
- RJ Reynolds Tobacco Co.
- Site
- MN Depository
- Author
- Orloff, Ken (RJR Biochemist)Biochemist and Nystrom's assistant in 1982. (Source: RJR Who's Who NMLRP)
- Nystrom, Charles W. (RJR Biochemist, Microbiology Section Head '76)Biochemist employed by RJR in 1954, Head of the Microbiology Section of the Analytical Research Division in 1976. He was F. Colby's assistant and worked with additives in 1983.
- Recipient
- Colby, Frank G.
- Copied
- JAG
- AR
- Named Person
- White-Froeb
- Kauffmann, F.
- Morris, James F.
- Koski, Arthur
- Johnson, Lavon C.
- Named Organization
- New England Journal of Medicine (pub)
- Thesaurus Term
- Research Studies
- Environmental Tobacco Smoke
- Industry Response
- Data Analysis
- Respiratory Diseases
- Educational Level
- Spousal Studies
- Males
- Confounders
- Socioeconomic Status
- Pollution
- Keyword
- FEF25-75%
- Spirometry
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