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Mayo Clinic

REVIEW 439

Date: 20 Aug 1988
Length: 2 pages
300507144-300507145
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mayo_sep02 20280416-20280417

Abstract

Reviews paper titled "Cigarette Smoking and the Acquired Immunodeficiency Syndrome". Reports on paper's position that smoking affects immunoresponse thereby increasing risk of "mainfesting an AIDS-related condition." Opines that "it is likely that there is a positive association between smoking and AIDS because smokers may more often get into a position [drug use and sexual activity] where they are exposed to the virus."

Fields

Type
Report
Company
British American Tobacco Co.
Site
Guildford Depository
Author
Lee, Peter N. (TAC Biostatistician)
Frequently funded by the tobacco industry to criticize and discount published and epidemiological studies that linked between tobacco smoking and health damage.
Named Person
Berger, I.R.
Named Organization
Annals of Internal Medicine
Thesaurus Term
Industry Consultants
Research Studies
Smoking
Acquired Immune Deficiency Syndrome

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Page 1: 20280416
TK1726 REVIEW 439 CONFIDENTIAL Sublect ref. "Clgaret=e Smoking and the Acquired Immunodeficiency Syndrome" L.R. Berger Annals of Internal Medicine (1988), 108, 638 This is the first Indication I have seen in the medical literature that smoking may increase the risk of AIDS. The suggested mechanism is by smoking affecting the immune response so increesing the chance of manifesting an AIDS-related condition. While ~ am unable to comment on the validity of the cited evidence relating smokin~ to the Intmune response or how this would affect the chance of getting AIDS, I feel that it £s likely tha~ there is a positive association between smoking and AIDS because smokers may more often geC into a poslClen where they are exposed to the virus. Smoking is linked with both drug-taking and increased sexual activity and ~U would not at all surprise me if a study found that AIDS sufferers are more often smokers than average. Because of this ~t would need a very careful study =o test the theory postulated 0 BATCh dncllrn~.nt fnr Mgvn Clinic l& l~c~.mh~.r ~NN1
Page 2: 20280417
-2- by Berger. There is an obvious danger, however, that a less than careful study will in due course be published purporting =o show that smoking increases the risk of AIDS. This could have big media impact. P.N. Lee 20.8.88 BATCo document for Mayo Clinic 14 December 2001

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