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R.J.Reynoids T' ~cac;crD n9n October 21, 1987 Dr., A. W'. Spears LoriTl'ard Research Center 4201Engll i sh Street Greensboro, NC'2742p Dear Alex: As you know, it is hoped that the CIAR'(Center for Indoor Air Riesearch)i, onceitisoperational,wi'1111 su~p~erviseai strategic plan for the effilcilentt allocation of resources for research on the envi'ronment 1 tobacco smoke problem. Once selected, the Executive Dilrector wi'll be absorbed wilth start-up ad'ministrative matters, revilew of the scilence rellatilve to, indoor ailr qual ity and becomi'ng familliar with the issues. Iniorder to assist in developilmgi a strategic pllan,, we at Reynolds suggest that a group of scientists wilth legal counsel gather to consider a strategic plani(',taki'ng, intolaccount short-, medium-, and long-range research needs) for all''~ocating resources to scientific research. Before thils meeti ng, eachiparti!cipant shoul d' be fami li ar at l east wi th the Introductions and chapter he~adi'ng&ofboth the National Academy of Sciences" 1986 publication on environmental tobacco, smoke and the 19861Surgeon General"s Report. A revilew of those dbcuments will focus attention on what claims are being made about ETS and what research, is said to support those claims. At the meeting,iwe might begilniby briefly reviewiing past and currentl'y sponsored'.research from the perspective of'how that research speaks to those claims. Then the particip~ants~should bepre~pared toadldhess the fol1owiing, questions: 1. What are the specific areas tni which the most damaging claims are being made? 2. What research iis necessary to, speak to those cllaims?, a. What iis the probablle. co~st and duration of suchiresearch? b. What Instituti'ons or researchers are available to conduct such research?

3'.. What research woul dl be benefi ci al i n the general area of indoor ai r qualIty?. a. cost and duration; b, availabi1iity of researchers. 41. Can we antiici!pate future claims that may be made about ETS and~begin research in those areas? 5. Are we presently devoting!resources to:research that has a minimal probabilliityofadvanci'ng scientific knowled'ge!in keyareaso~f c~oncern?IWe believe that withsome advance thought, the participants can develop: the out'l i ne of a researchiprogramithat wi l l be nat oniiy a useful tool to the. CIAR' andl its Executive Di'rector, but may provid'e assistance to the indiividuall companies in assessi'ng, their commitment to support research on i,ndoor air qwal ity. Dr. Fred Seitz of Rockefeller Uhiversilty has agreed to host a meeting for this purpose. Y'ou should hear from hi'mi shortiy, with details about the time and place. We hope you wilUl' be able to attend., Stnicerely, George D."W6wton Deputy Generall Counsel - Liti'gation RJR Nabisco, Inc. tNary E. r Associate Counsel - R&D R. Ji. Reynolld's Tobacco Company :Urh