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HARVARD MEDICAL SCHOOL DIVISION O/ RESPIRATORY DISEASES GARY L. HUBER, M.D., CHIHP William Shinn, Esquire Shook, Hardy & Bacon Mercantile Bank Tower 1101 Walnut Kansas City, Missouri Dear Bill, 64106 Mail'rng Address: BETH ISRAEL HOSPITAL ,30. BROOKLINE AVENUE BOSTON, MASSACHUSETTS 02219 - (d17) 733-2391 As we discussed on the telephone, I am enclosing a list of proposed modi- fications to our Charlesgate West animal inhalation facility. This list of recommendations was developed by Dr. First, working in conjunction with Dr. Trum areas, all of which need further clarification and better understanding. these recommendations. Both Dr. First and I have the highest regard and respect for Mr. Kennedy. When we hear from him, I will forward all of the information to you in the hopes that we can at that time ask the tobacco industry sponsors of our program for help regarding these matters. I belive, and I think I am speaking for all of our investigators, that our research program has reached a critical point of achievement and momentum, and I hope we can do everything pos- sible to keep that momentum going forward in a positive direction. We have identified, in some instances unexpectedly, critical new information in several and Dy: L-age, who are the two veterinarians at Harvard Medical School responsible overall for facilities of this nature within the University system. I have asked Mr. John Kennedy, of Walsh Brothers Construction Company, who has worked closely with us in the past on the initial innovation and on the development of facilities for the pigeon program, to give us his best estimate of the cost of implementing ~ I appreciate your help and concern in this matter, and please do not hesi- tate to call me directly if I can further clarify any of these matters. My warmest personal regards and highest respect, Sincerely yours, Gary L. Huber, M. D. , Chief Division of Respiratory Diseases BETH ISRAEL HOSPITAL