International Cancer Congress Seattle, Wash., 820908

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International Cancer Congress Seattle, Wash., 820908 - 820915

Date: 25 Aug 1982
Length: 8 pages
03734971-03734978
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Area: LEGAL DEPT FILE ROOM
Type: MEMO, MEMORANDUM; AGEN, AGENDA
Alias: 03734971/03734978
Site: N14
Copied: Stevens, A.J.
Request: R1-004; R1-041; R1-071; R1-073; R1-093
Named Person: Amacher, D.; Ames, B.; Archer, M.; Auerbach, O.; Baird, W.; Bartsch, H.; Bedwani, R.; Bekesi, J.; Bjelke, E.; Blair, W.; Blot, W.; Boyle, P.; Busbee, D.; Cartwright, R.; Castonguay, A.; Clarke, E.; Cleton, F.; Connelly, R.; Croft, W.; Curnen, M.M.; Czaja, R.; Damber, L.; Daube, M.; Dean, J.; Devesa, S.; Dewar, R.; Digiovanni, J.; Dimauro, J.; Eckert, D.; Enstrom, J.; Evans, R.; Fliessbach, J.; Fraumeni, J.; Fujimoto, I.; Furst, A.; Garfinkel, L.; Geddes, M.; Gray, N.; Green, L.; Gritz, E.; Grunberg, N.; Hammond, E.C.; Hansonpainton, O.; Harada, T.; Harnden, D.; Harvey, G.; Hecker, E.; Henderson, M.M.; Hengst, J.; Henry, C.; Herrara, C.; Hinds, M.; Hirayama, T.; Hirono, I.; Hodgson; Hose, J.; Hsu, I.; Janis, J.; Jansson, B.; Jean, T.; Jonas, A.; Khanduja, K.; Knudson, A.G.; Koller, L.; Kouri, R.; Kupper, L.; Kuroki, T.; Kvale, G.; Leibovici, J.; Lewtas, J.; Li, J.Y.; Locke, S.; Magee, P.; Mathe, G.; Mclemore, T.; Mills, P.; Mittman, C.; Mommsen, S.; Mori, W.; Mountain, C.; Muir, C.; Mulvihill, J.J.; Nagao, M.; Namekata, T.; Newell, G.; Nostbakken, D.; Nunezcortes, J.; Oconor, G.; Pastorino, U.; Paterson, M.; Pendergrass, T.; Perk, K.; Petersson, B.; Pike, M.C.; Prentice, R.; Preussmann, R.; Radford, E.; Rajewsky, M.; Ramanathan, J.; Rapp, F.; Rasmussen, R.; Reimer, R.; Richters, A.; Rimer, I.; Rogan, E.; Rosin, M.; Russell, Mah; Saccomanno, G.; Sandberg, A.; Schottenfeld, D.; Schroeder, T.; Selikoff, I.; Shanmugaratnam, K.; Sherif, O.; Silber, W.; Slaga, T.; Steinfeld, J.; Stich, H.; Sugimura, T.; Trell, E.; Trichopoulos, D.; Tsuchiya, E.; Upton, A.C.; Vandenberghe, H.; Vannevel, J.P.; Wattenberg, L.; Weinstein, I.B.; Weisburger, J.; Wilkinson, G.; Wynder, E.; Yang, S.
Document File: 03734507/03735036/S and H Re Smoking and Health General Volume 9 820800.
Date Loaded: 05 Jun 1998
Litigation: Stmn/Produced
Author (Organization): Leonard Zahn + Associates
Named Organization: American Cancer Society; Cancer Inst Hospital; Comite Francais Deducation Pour La; Ctr, Council for Tobacco Research; Lutheran Brotherhood
Master ID: 03734507/5036
UCSF Legacy ID: wsy61e00

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INFOR'MATIONAL MEMCANDUK SUBJECT: International Cancer Congress Seattle, Wash., Sept. 8-15, 1982 Au&-st 25, 1982 I've obtained a copy of the programifor this meeting; it has. 28'3 pages and numerous presentations on different aspects of tobacco anid health. Here is a rundown of the relevant items (P = poster presentation): "Cellular targets and~host genes involved inichemical carcinogenesis" -- I.B. Weinsteiny N.Y. "DNA modification and repair in relation to carcinogenesis" Rajewsky, Essen, W. Germany. "Induction of tumors by viral information" -- F. Rapp, Hershey, Pa. "' "Mechanisms of tumor promotion: evidence for the multistage nature of tumor promotion" -- T. Slaga, Oak Ridge, Tenn. "Inhibition of chemical carcinogenesis" -- Lee Wattenberg, Minneapolis. "Cancer prevention -- overview" -- R. Bedwani, Alexandria, Egypt. "Social psychology applied to deterrence of cigarette smoking in adolescents: some promising results and' possibilities as a model in camcer prevention" -- Richard~Evans, Houston. "The controversies inicancer prevention and screening" -- M.M. Henderson, Seattle. "Classification and prognosis of lung cancer" -- C. Mountain, Houston. (Part of a postgraduate course.) "Detection of precancerous bronchus metaplasia in heavy smokers and its regression following retinoid treatment"' -- G. Mathe et al, France. "A surveillance study of asymptomatic black males from a high risk area" -- W. Silber, Cape Town, S. Africa. "Mutagenicity and carcinogenicity of environmental combustion and comparative sources" -- J. Lewtas, Triangle Park, NI.C. emissions from Research "Binding of environmental carcinogens to asbestos and mineral fibers" -- G. Harvey, Quebec. _ "Comparison of nickel and cadmium carcinogenicity -- Arthur Furst, San Francisco. eonar°d n PUBUlB RELATIONS COUNSEL Associates,InG in the same ra6t- (P. 0. BOX 223)' 13' LINCOLN ROAD GREAT NECK, N:Y, 11021 (212)', 895-7445

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2. "Effect of cigarette smoke on the covalent binding of benzo(a)pyren~e with DNA of rat trachea in vitamin A deficiency" -- K. Khanduja, Chandigarth, India. "The effect o'f exposure to whole cigarette smoke on short-term endpoints in BC3'F11/Cum mice" -- Carol Henry et al, including R. Rasmussen, and R. Kouri, Bethesda, Md. (P)(This is a CTR-supported study). "Effect of metals on cigarette smoke-induced genotoxicity: . a study of multiple risk factors" -- M. Rosin et al, including H. Stich, Vancouver. "The effect of lifetime exposure to whole cigarette smoke in BC3F1/Cum mice" -- Carol Henry et al. (P) (CTR support.) "Multistage tumor development in the esophagus -- the first complete experimental analysis of an etiologic modell situation involving cocarcinogens as environmental risk factors of cancer in man," -- E. Hecker et al, Heidelberg, WE. Germany and Coral Gables, Fla. ,+The workplace as a cause of cancer -- the importance of epidemiolog,, ~n assessing risks" -- David Schottenfeld~, New York. "The changing cigarette: its influence on mortality rates" -- Lawrence Garfinkel, New York (American Cancer Society). The next nine papers will be given at a session titled "Tobacco Chewing and Smoking iniCancer Causation"' that will be cochaired by E. Cuyler Hammond and Ernst Wynder: 1. "Genotoxicity in the saliva of betel nut and tobacco chewers as a predictive tool" -- H. Stich, Vancouver. 2. "Chewers mucosa, a potentiall oral precancerous condition An Sri Lanka?" -- J. Ramanathan, Sri Lanka. 3. "Cigarette smoking related cancers in Scotl'and~, 19111!-1978" -- P. Boyle, Glasgow. 4. "Cancer mortality and smoking cessatioo among California physicians" -- J. Enstrom, I.os Anigeles. 5. "Chronological analysis of the relation between lung cancer and cigarette smoking" -- W. Mori, Tokyo. 6. "Smoking,, AHH inducit:ility and respiratory tract neoplasia: a prospective study in m1iddle-agt-d' men" -- E. T'rell et al, Sweden. 7. "Determinationiof smoking-specific lung cancer rates ir e:pidemzologic studies" -- E. Radiford, Pittsburgh,. 8. "Cigarette smoking and radiation exposure in relation to cancer

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mortality in Hiroshima: and~Nagasaki, Japan" -- R. Prentice et al, Seattle and Tokyo. 9. "Smoking and cervical cancer: evidence from a study of.cervical dyspllasia"' -- E. Clarke et al, Toronto. W "Overview and extrapolation from mutagenicity" -- P. Magee, Philadelphia. r"Cancer ecogenetics: genetic susceptibility to carcinogens" -- J'.J. Mulvihill, Bethesda. "Response of chemicals either identified or suspected to be carcinogenic in humans in multiple short-term tests" -- H. Bartsch, Lyon, France. "Interspecies, interindividlual andlintercell-type variations of metabolism of benzo(a)pyrenie inlepidermal and dermal cells" -- T. Kuroki, T'okyo. "Positive correlation between highiA'HHlactivity and primary lung cancer in humans" -- R. Kouri et al, including CTR grantee T. McLemore, Bethesda:, and Houston. "Cancer and total mortality among vitamin supplements users" -- Enstrom,, Los Angeles. "Coffee consumption and cancer: a prospective study" -- E. B j,elke, Bergen,, Norway. "Dietary habits and lung cancer", -- G. Kvale et al, including Bjelke, Bergen and Bethesda. "Dietary factors and lung cancer mortality. The Lutheran Brotherhood Study 1'966-1977"' -- Bjelke et al, Bergen, Bethesda: and Minneapolis. "Dietary cholesterol consumptioniand lung cancer risk in a multiethnic populiation"' -- M. Hinds et al, Honolulu,. "Dietary intake of po:ta:ssium and sodium influences cancer rates" -- B. Ja:nisson, Houston. "Experimental induction and'icharacterization of pulmonary large cell carcinoma"' -- W. Blair, Chicago. "Comparison of experimentally induced carcinoma with human large cell carcinoma of the lung" -- J. DiMa:uro, Chicago (Bliair's coworker ),. "Biological, ultrastructural and biochemical evidence for a retrovirus etiology of pulmonary carcinoma of sheep -- a: model system in comparative oncology" -- K. Perk, Israel. (P)' "The impact of cancer on black and' white females in Metropolitan

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Detroit"' -- D. Eckert, Detroit. "Cancer mortality among immigrants to Canada" -- R. Dewar, Edmonton. (P) "Quality of cancer data obtained by household interviews"' -- R'. Czaja, Chicago. (P) "Time trend data of histological subtypes of lung cancer in Japan: observation at the Cancer Institute Hospital from 1961-1978" -- E. Tsuchiya, Tokyo. (P) "Cancer incidence in Hispanic populations in urban and rural areas" -- P. Mills, Houston (P) - "Relationship between birth cohort effects and falling mortality rates of lung and stomach cancer in Great Britain and other countries" -- J. Jands and L. Kupper, Chapel Hill, N.C. (P) "'Overview: naturally occurring carcinogens in human cancer development" -- J. Weisburger, Valhalla, N.Y. "N-nitroso compounds in the external environment" -- R. Preussmann, Heidelberg, W. Germany. "Formation of N-nitroso compounds in vivo" -- M. Archer, Toronto. "Mutagens and carcinogens inifood produced by cooking and storage" -- M. Nagao et al, including T. Sugimura, Tokyo. "Naturally occurring carcinogens of plant origin" -- I. Hirono, Tokyo. "Radiation (as a natural carcinogen)" -- A.C. Upton, New York. "Geographic epidemiology: overview" -- G.. O'Conor, Bethesda. "Worldwide trends in canicer incidence" -- C. Muir, Lyon, France. "The etiologic cliues from cancer mortality maps in China"' -- JI-Y. Li "Field studies in high risk areas in the U.S." -- W. Blot and J. Fraumeni, Bethesda. "International studies of'breast cancer" -- D. Trichopoulos,Athens, Greece. "Inverse correlationibetween serum cholesterol and fatal neoplasia in middle-aged men" -- B'. Petersson, Sweden. (P') 03734W4 "Effects of agents of environmental concern on the immune response and their possible epigenetic role in carcinogenesis" -- J. Dean, Research Triangle Park.

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"Heavy metals: immune system modulation Koller, Moscow, Ida. and carcinogenesis" -- "Facilitation of cancer cell metastasis by inhalation of air pollutants" -~ A. Richters, Los Angeles. "Antitumor cxytoxicity of human pulmonary alveolar macrophages in lung cancer" -- J. Hengst, Los Angeles. (P) "Inihibitory and stimulatory effects of macrophages on tumor growth" -- J. Leibovici, Tel Aviv. (P) "Cancer mortality in physicians and lawyers. A birth cohort study" -- M. McCrea Curnen, New York. (P)' "An occupational cancer mortality study in the Gary-Hammond-East Chicago-SMSA, Indiana" -- T. Namekata, Seattle. (P) "Lung cancer cell types and occupational exposure: case controls and case-case study"' -- M. Geddes, Florence, Italy. (P) "Environmental asbestos and mesothelioma inidairy calves Croft, Madison, Wis. (P). "Cancer mortality among plutonium and other nuclear workers" -- G. Wilkinson, Los Alamos, N.M. (P) "An epid~emiologic case-control study of bladder cancer inia predominantly rural district in Denmark" -- S. Mommsen, Aarhus, Denmark. (P) "Contribution and mechanisms of genetic predisposition to cancer" -- A.G. Knudson,, Jr., Philadelphia. "Chromosomes, cancer genes and carcinog;enesis" -- D. Harnden, Birmingham, England. "Genetic markers of cancer susceptibility" -- F. Cleton, Amsterdam, The Netherlands. "Human heritable disorders linking carcinogen hypersensitivity and DNA repair deficiency with cancer proneness" -- M. Paterson, Ontario. "Cigarette smoking and lung cancer: an overview" -- Oscar Auerbach, East Orange, N.J. "Lung cancer in uranium miners" -- G. Saccomanno, Grand Junction, Colorado. "Pathology of nasopharyngeal cancer - correlations with epidemiology and environmental carcinogens" -- K. Shanimugaratniam, Singapore. 03'7349'75 The following five papers will be given at a session titled

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?, 6 ~. "'Smoking and Cancer: A Comprehensive Approach" andicochaired by Nigel Gray, Australia, and Allan Jonas, Los Angeles. Gray will open withian overview. 1. "The politics of tobacco abuse" -- Jonas. 2. °Obstacles to health promotion` -- M. Daube, Edinburgh. 3. "The role of associations and the Comite Francais d'Ediucation Pour la Sante irn the prevention of smoking in Franice" -- T'. Jean, Paris. .4. "^R'ecent advances in treatment for smokers" -- M.A.H. Russell, London, England. 5. "Prevention of the smoking epidemic in Egypt" -- 0. Shierif,. Cairo. "Time-trends in cancer incidence and mortality in the United States" -- S. Devesa, Bethesda:. "Cancer mortality and life-style among active Mormons" -- J. Enstrom, Los Angeles. "Oral cancer in Scotland, 1911-1978" -- P. Boyle, Glasgow. "Trends of lung cancer incidence and their histological distribution in Osaka` -- I. Fujimoto, Osaka, Japan. "The incidence of mesothelioma in the U.S." -- R. Connelly, Bethesda. "Epidemiology of bladder cancer iniYorkshire, England" -- R. Cartwright, Leeds. "Life-style variables in cancer etiology" -- Wynder. "Assessment of low-level risks" -- M.C. Pike, Los Angeles. "Carciniogens and a:nticarcinogens"' -- B'. Ames, Berkeley, Cal. "Creating positive news for cancer control" -- Irving Rimer, N.Y. (American Cancer Society.) "The performance of mass media in covering hig,h:priority cancer control topics" -- J.P'. Van Nevel, Bethesda. "Braini,, behavior and human immunity" -- S. Locke, Boston,. (P) "Congenital chromosome abnormalities and predisposition to cancer" -- H. Van den Berghe, Leuven, Belg,ium. 03,y34Ws "'Chromosomes and carcinogenesis: public health application"' -- A. Sandberg, Buffalo, N.Y. JL ,. s.

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"Structural factors that enhance or attentuate the carcin~ogenicity of polycyclic aromatic hydrocarbons" -- S. Yang, Bethesda. "High~degree of immune dysfunction among asbestos workers at high risk of developing neopl'asia" -- J. Bekesi et al, including Irving. Selikoff, New York. "Regional variations in lung cancer reporting in the U.S. The centralized cancer patient data system" -- R. Reimer, Seattle. "3H-Benzo(a:)pyrene metabolism in lungs of naphithallene-treated mice" -- CTR grantee R. Rasmussen, Irvine, Cal. (P) "Synicarcinogenic effect of the environmental pollutants cyclopenta(cd)pyrene and benzo(a)pyrene in mouse skin" -- E. Rogan, Omaha. (P) "Comparative metabol'ism of benzo(a)pyrene in primary cultures of mouse and hamster epidermal cells" -- J. DiGiovanni, Philadelphia. (P) "Effects of the cocarcinogen benzo(e)pyrene on the binding,of thee carcinogen b:enzo(a:)pyrene to DNA' in hamster embryo cell cultures" -- W. Baird!, West Lafayette, Ind. (P) "Benzo(a)pyrene transport into human cells via lipoprotein carrier" -- CTR'grantee D. Busbee, Den~ton, Tex. (P) "Thie effect of carrier protein on the oxidation products of benzo(aYpyrene of microsomal cytochrome P-450" -- 0. Hanson-Painiton, Oklahoma City. (P) "Developmental effects of the environmental carcinogen benzo(a)lpyrene" -- J. Hose, Los Angeles. (P) "Economic costs of cancer in the U.S." -- T. Hodgson, Hyattsville, Md. "Food additives and coffee as risk factors" -- G.Newell, Houston. "Parental exposures in cancer risk in offspring: epidemiologic approaches" -- T. P'end'ergrass, Seattle. "Inibornisusceptibility synidromes" -- T. Schroeder, Heidelberg, W. Germany. "Cell transformation by some Ames negative chemicals in Syrian ` hamster embryo cells"' -- D. Amacher, Groton, Conni. "An assay for mutagenic activities in human saliva: smokers vs. nonsmokers" -- J. Fliessbach, N.Y. . 03'7349'7'7 "Human hepatocytes and pulmonary alveolar macrophages mediated mutagenesis of chemical carcinogens" -- I-C. Hsu, Bethesda.

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"CEA and sputum cytology in a population risk" -- C. Mittman, Duarte, Cal. (P) with a: high lung cancer "Cigarette smoking and appetitive behaviors: implications for cancer" -- N.3 Grunberg, Bethesda:. (P) "Environmental mutagens, carcinogens and tumor promoters" -- T. Sugimura, Tokyo. The next five papers will be given at a session titled "Smoking, Chewing and Cancer" cochaired by C. Hierrara, Argentina, and Jesse Steinfeld, U.S. 1. "Lung cancer prevention: why, where and how the UICC has tried to assist this political andicultural process" -- Nigel Gray; Melbourne, Australia. 2. "The woman smoker: current trends in behavior and biomedicine" -- E. Gritz, Los Angeles. 3. "Smoking and chewing in the developing world'. the epidemiological approach" -- T. Hirayama, Tokyo. 4. "Health behavior change: an overview" -- L. Green, Houston. 5. "The prevention of smoking among teenagers" -- D. Nostbakken, Toronto. "Proportion of lung cancer cases attributable to occupational exposure and!cigarette smoking" -- U. Pastorino, Milan, Italy. "Male lung,cancer in northern Sweden. A descriptive and analytical epidemiologic study" -- L. Damber, Sweden. "Fate of the tobacco-specific carcinogen NKK inimice, rats and hamsters" -- A. Castonguay, Valhalla, N1.Y. "Alpha-l-antitrypsin.as a biologic marker of malignancies" -- J. Nunez-Cortes, Madrid. "Effects of vitamin C on cigarette smoke inhalation toxicity in Syrian golden hamsters" -- T. H'araida, Tokyo. (P'), Not included in th~is memo are those sessions covering the efforts of voluntary agencies in combating cancer and smoking. Also omitted were most papers dealing withiantismoking programs aimed at young people. SN9A31S r. b coiw NJ m (.T21 AI~~~2I

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