Lorillard
Clinical Record Tissue Examination Dog 5097
Fields
- Author
- Auerbach, O.
- Type
- FORM, FORM
- Area
- SPEARS/EVPOR
- Alias
- 01423003/01423022
- Litigation
- Flag/Trial Exhibit 6989
- Stmn/Produced
- Txag/Trial Exhibit 6989
- Request
- R1-132
- R1-004
- R1-042
- R1-045
- R1-046
- R1-053
- R1-061
- R1-068
- Site
- G65
- Author (Organization)
- Va Hospital
- Date Loaded
- 05 Jun 1998
- Document File
- 01422934/01423110/Inhalation Studies Dogs Pmo Bioassays Related Material Enviro Control 75
- UCSF Legacy ID
- jtl88d00
Document Images
NtoitQlirtl Forwl b1111
1(cv. Jau. 19311
rronlLLll;LLtt>tl
By Iftm-aworthe lludKetClrcuier A-3!
I-
CLINICAL RECORD ~ TISSUE EXAMINATION
Dog 5097
SPECIMEN SUBMITTED BY
SPECI M EN
e-
eATE OBTA I NED
BRIEF CLINICAL HISTORY(lndnde duraliono/ltrion and rapidity o(prmofD, if a ntopiasrnl
PREOPERATIVE DIAGNOSIS
OPERATIVE FINDINGS
POSTOPERATIVE DIAGNOSIS
«:1~-,~1--8U3/-1
I SIGNATURE AND TITLE
PATHOLOGICAL REPORT
NAMEOP LABORATORY Laboratory of Senior Medical ACCESSION NO(5). --
Investigator, VA Hospital, East Orange, NJ Dog 5097
(Qross desaiption, Itiitodoqib aamination and diapna ra) Tongue
.
The mucous membrane is intact. The tissue cuts with~usual resistance and on section
the muscle is firm and brown.
Larynx
The mucous meitnbrane of the epiglottis, true an&false vocal cords, aryepiglottic
folds andinfraglottic region is smooth and grey in appearancea
Trachea
Lying in the anterior wall of the trachea approximately 6cm. from the vocal cords
is an oval opening which measures 7mm. by 6mm. The edge of the opening is grey-
white in appearance. The remainder of the trachea, major bronchi and branch bronchi
is lined by a smooth grey surface.
(Continue on reverse side)
SIONATURE OF PATHOLOOIST
AGE SEX RACE
PATIENT'SIDENTIFICATION (For typed or written entries Qive:Name-last. Arst.
middle; arade; dete: hospitaior medical /aoility)
Dog 5097
REGISTER NO.
I CSATE
i
IOENTIFICATION NO.
WARD NO.
TISSUE EXAMINATION
lituntlurA h'ortu315
I
iN

Stendsrd fenn S03
Rev. Au9ust 11934
Surevu otthe Oudget
Grculbr A-32
CLINICAL RECORD
i
DATE OF ADMISSION - 1: DATE OF DI5CHAFlGE
U.S. conlI-c,rvr ryiNnnGtFrraa ,1: t" L7y'. I -' : Ol.
NARRATIVE SU1H1MARX
(SiIIn and dataat and of narratire)
nn(' 5;)~,7
'VUMBEROF DAYS HOSPITALIZED
2_-
Tracheobronchial Lymph Nodes
The left superior tracheobronchCal lymph nodes measure 1ern., cut with slioiltly
increased resistance and on section are brey-brown in appearance.
The right superiortracheobronchial ~ymph nodes cneasure 1-1/2cm., cut with
slightly increased resistance and are grey-brown in appearance.
The right inferior tracheobronchial lymph nodes measure 1-1/2cm., cut with
usual resistance and on section are grey-brown -i appearance.
The left-apical lobe measures"9-1/2cm..in its greatesc apicobasal direct:,:on.
1'heiissue cuts with increased resistance and on section shows the presence of
,firm brown areas. These firm, brown areas measure l-1/2cm. in its greatest
diameter.-- The-remainder of the-lung parenchyma is firm and brown-in appearance.
Lungs
Vie_,left cardiac lobe tneasures 7cm. in its greatest apicobasal direction. The"
. . ,
t#-nue -cuts with increased -resistance and on sectioc-~ the parenchyma-is--tirm-and -
brown in appearance. No definite masses are seen within this lobe.
tissue cuts with increased resistance and on section the lung parenchyma is firm
and red. There are firmer areas within the lobe which measure appro::imately 5mm.
to 1cm. In other regions, the tis-sue ."; brown and has lost much of its res i t i ency.
...._R_ . ~ ~; .-., .~ ~ .... , _ -.. , . _ _ . . .y. d ~ ..
=_r «.-. ._.~ .. . - . -- ... ~ : .._"-. : . ~.:.~~~i. . :. '_. . .- - ~ ._. " ..__
Thexi~ht cardiac lobe measures 6cm. in its a i.cob
greatest p asal direction. The
a- ~ -. . . _ . .
P_
. . ._
y. ~ ~. , i
- - -.. - - . ,.. c,.. .: .. 4. ~ ' ~= Y .. .
~
T'he right apical lobe measures 10cm. in~its oreatest apicobasal direction. The
L~sst~e,,cuts with slightly increased resistance and on section shows the presence
b~f occasional firm, red zones which measure approximately lcm. in diamecer. In
xhe.remainder of the.lobe, the parenchyma is-bXown and has.loSt,l7ruchqf its resilien-
lobeis broraq and slightly firmer than normal.
fclr' s
,The left diaphragmatic lobe measures 11-1/Zcm. in its greatest apicobasal directicn.
he ti,ssue cuts with increased resistance and on section shows the presence of a
wedge shaped focus . The base of the wedge lies toward the diaphram and the
ex toward the.hilum. Within this zone, which is iirm and brown, are man~! small
L -
~sulmonary arteries whose lumens are fi11;9~d with red thrombi. The remainder of the
L5A': %
~_r .. _~ {Uae pdditional afleets of thialorm (Staadard Fo_rm 501) if more space is required)
SIGNATURE OF PHYSICIAN ,
I DATE
IDENTtF1CATION NO.fORGANIZATION -.. - . . -.. ~ . .. _
PATtENT'S IDENTIFIGATTON (For. typed or wtitten erttriea ~ive: Nnarte-laat, first;;
DOG 5097miadle; grada; date; l+oapda7or melticaLfacility)
NARRATiYE Sl1MMARY
c:;~- :~. ~.~ -. - - --- - - - ._..___----- ~ -- -- -
O suindsrti Forrni`sos
~
C4

3tondo.d Form 502
Re.. AUgwl 19S/'
BureauoElhoBudget~
Crcalas A-32
CL1NiCAL RECORD i
ATE OF ADNtiI551ON' ~+r. I 'c vr v-- .r..+......
Y.:. 4J-.4.1.~~~.:T,rM1. /I
. c:. I.. .. , a:.. . a. .
NARRATIVE SUMMARY
_ OC . ,- ' ,
i NV.118ER.OFDAYS MOSP:TALIZED
(Sign and date at end of'narrati~+e)
The right intermediate lobe measures 4cm. in i~s ;rea'c~>sL apico~asai d.rec_::.~1.
The tissue'cuts with slio:ltly increased resistanct' an,?' s:io:-is ::'Ze preseace t_
firm, brown parenchyma.
The ridht diaphragmatic lobe measu es 7'-1/2e~n, in :ts~ ;;reatest apico:--asal tlirection.
The tissue cuts with slightly incr ased resistance and on-sect;.oz tite parelzca.rlaa
has lost 8ome of its resiliency an is brown ;n appearance. -
ft
I ...
Heart
The heart weighs 92.4gms.. The vis~eral surface of the parietal pericardiuil and
the parietal surface of the visceran pericardium are smooth and shiny and tl,e
pleural space is patent. There is the usual amount of clear fluid presen=
within the pericardial cavity. There is th,.! usual amo,lnt of subepi carc: ;al rnL
present.
The wall of the right atrium measures lmm. in thicicness. The lumen of the
auricular appendage is patent. No visible thrombi are present. The tricuGpi~:d
valve measures 8-1/2cm. in circumference. The free edge is sliohtly beaded. The
chordae tendineae are fused. They are not thickened and not shortened.
The wall of the right ventricle measures from 2mm. to 3mm. in'chic!''-ness. The
apex is greatly rounded. The trabeculae carneae and papillary muscles are, f_ac.
The pulmonic value measures 3-1/2cm. in circumference. 'ilte ,)ulmoa_;.c cusps are
not shortened, not thickened and are not fused.
The wall of the left atrium measures 2,pm. in thicl':ness. The enclocardial suriace is
smooth. ThY auricular appendage is paZent. The mitral valve measures ~cm. in
circumference. The chordae tendineae are in areas Zused, they are not th~.c_.ened
and not shortened.
The wall of the left ventricle measures 1cm. in thickness. The ape:c is sLarp.
The muscle is firm and brown as is the muscle of the interventricular septum.
The trabeculae carneae and papillary muscles are rounde&. The aortic valve
measures 2-1/2cm. in circumference. The aortic cusps are not thic'-ened, not shortened
and not fused.
(Use additional sheets of this form (Sta,ndard Form 502) if more space is required)
yellow atheromatous plaques.
The coronary arteries are patent thrcag:zout their entire course and contain no
The coronary arteries arise in their usual location. The coronary ostia are patent.
SIGNATURE OF PMYSICfAN
( DATE i IDENTIFICATION NO. I ORGANIZATION.
PATIENT'S IDENTIFICATION(For type d or wpften entties Bive:lYaate-last, ftst, ( REGISTER NO.
middlo: grade; datet hospita'd or atDdiuiLtagjlity)
DOG 5097 '
WARD NO.
i
NARRATIVE SQMMARY ~
9tiaadarQ Form aot
5a.-111-

~ .` Sfandard tene 502
* t Rev: AuqOSI 1934
6weou of th. ludget
Ckculor A-32
DATE OF ADMISSION , -.. . I DATE OF DISCHARGE.
CIUNICAL _RECpRD ~ NARRATIVE SUMMARY
. . Jp`' 5
; NUMBER.OF 3AY5. HO3P1T%t_IZD
~
~ ifd~'e i
I I
- - -
(Srgn and det'e+aterrd-v}~aeSt_-"°'
.
_--- _°-_ .-_
Aorta
~; - - - .
The :aorta. retains its res.i_liency.
-
along
the;course.
Veins
Liver
plaques
present
.Qnly-.smalL,sections of.the veins are present'.'"It`appears hiiat'some of these
contain.thrombi and this will be ascertained on microscopiic examination.
prominently.
_._d , _
sharpe The tissue cuts with usual resistance and on'section sinusoids stand out
e~_ver we
T
._4 s .6ms. T e capsu e is smoot`I and brown. The liver edl,e :.s
Li >:. h 437 2 n 1 f
h
i
"
`
measures 1inm. iii thi..c'rness.
The
lumen is patent and
The cystic,~hepatic and common bile d,ucts:are. patent.
The
The
There are no yellow a t;ierornatous
capsule--~'_f the slAleen is sliohtly .,rri.nkled and
tissue cuts with usual resistance and on secLion
the splenic corpuscles stand
Spleen
IThe spleen weighs 39.1gm.
slate-grey in appearance.
Ga],lbladder
-
The ia.al1. ,of the gallbladder
containstclear,s green bile.
No adrenals were submitted.
Kidne s
Adr_._ena.Is - -
~
The lef tka ~gsdy a~diFi~nha! aheet9mof.thisTloeni (~tande d Forrri 30:) i(mora c ~ ieqpred)s~
SJGNATURE OR Pl'iY51C19AN DATE 70ENTIflCAT10N,N0 =.ORGAMZATION- °
.. a ts- .- . .. _. . . . _ . . , ... ... . ' .
The ripht kidney weighs 4G,5gus. _ The capsule stri ps with ease"LGavin, a smoocn'
surface 0.TLhe.;t:i,ssue ,cuts-:with usual- resistance a'nd'"on SectLo;R t-1e:`cortexx stancs
out prominently.from the medulla.,. The normal arch'itecture i1s maiiitained'. i,:ere
is congestion at the cort.comedullary junction. The cortex and medulla toetltier
measure 13mm. The cortex alone measures ~imm. The mucous melnbrane oz tne cahces,
pelvis. and, ureter is smooth.' S
rAT1ENT'8 IDENTIFICATION (For typed or wul ten en tnea qire:Nama-laat Brat, ,
middla `ra_de date~.doapil.lcr rAppbtJ! facility)
DOG 5097
_ L FtEGISTER NO.
,{ i
- `
surface.
-- _ ---
NARRATIYE SUMMARY
J
,-s
6GAildBPd 1'OrIII d0:
x.e.,.s.
out prominently.
2 ; t
'
_
4 t--
N
p W ,
p ...
r

` 4 Standardform 502
.
- - Rev:.AUgast 1954.
eurreu ef the ludger..
CircVler A-32
I - I a.e 5
(Sitn and dats at en o narrihre j
The tissue cuts with usual resistance and on section normal architecture is maintained.
The cortex and medulla stand out prominently because of congestion at the corticom
medullary junction. The cortex and'~medulla tooether measure l2mm. The cortex
~ 1:; -1,~. 1 .Itl., p3..'
CLINICAL RECORD I NARRATIVE SUMMARY DOG 5007
, DATE OF ADMISSION ' DATEOF DISCHARGE. NUMBER OF DAYS HOSPITAGIZFD
alone measures 7mm. The mucous membrane of the calyces, pelvis and ureter is
and orey. The lumen is patent.
~
Urinary Bladder
The wall of the urinary bladder measures 3mm. Ttie 1_IS,nen :.s narrow. Ti:e
mucous membrane is smooth.
Prostate
.
2 . . .w
.c. ,_
Testes and Epididymides
and on section the normal architecture'is maintained.
is patent.
The prostate measures 3cm. by 3cm. by 2-1/2cm. it cuts ~7ith usual resistance
Y. ',. YHI1:111.: JA/l~t
smooth
The prostatic laarenchyma
The testes and epididymides cut with usual resistance and
architecture to be maintained. The testes string easily.
on~ section show
the normal.
The mucous membrane is smooth and grey. The longitudi:nall folds are prominent.
Stomach
The mucous membrane is intact and is red in appearance. The ruoal pattern is
maintained.
Duodenum
The mucous membrane is intact.
Jejunum
Gastrointestinal Tract
The mucous membrane of the hypopharynx is smooth.
Esophagus
~
(I7se additiona! sheets of this form (St' ndard Form 501), if more apace is required)
SIGNATURE OF PHYSICIAN I DATS IDENTIFICATION NO. I ORGANIZATION
pATIENT'S IDENTIFICATION (For typsd or .,ritten_entlies give: Nams-last; frat;
aniddls; prad.; date:6ospitalor rrtndioaLfaeiGty)
DOG 5097
; WARD NO.
NARRATIVE SUMMARY
ata.naara form so2
St1.-i V

,
.. l
.
I -
-Srenderd ia.on 501
pw. Augvit 1954
=Wreou el fh. Wdgar
Qeeula. A-32
'Cl.1KtCAL RECORD
DAT6 OF ADMISBION
: ISign an~d3ra rca~tffip{ atrrlTatirsy-`
° "SIGNA'RttM O! PKYSlC1AN
'-- (Ua. additional sheets of this form (Standard Fqcrs><` 502) ' if more sppce is required)
( DATE 110 EhkT.Ff1CAT14N NG. ~ ORGANIZqT10N
and
left
w ~_ ' -- - - --- - .
PATIffNT'$ IDENTIFIGTION (For typ.d or writt.n entrie. Aira1VAm.-laat, hrat, l REGISTER NO.
-,~-WARd ~10.' _
_. --atiddi.: ir.d.; d.t...ho.pit.( or mtiiiGpLlwciLtr~ lI {
:.,; NARRATIYE SUMMARY
Dog 5097
~I_ a_. .° . . .
_. ._- fo.?... - - .. - __.. .. . .. -
T,,The villi are prominent. In areas, there
w.membrane. , .. . . _ .
n,:Cecum - , .
' ~ t-!°-.:. k''--..~. 5.~ 1=, . .
an faten'se congestion of the mucous membrane.
~_,l'cn._ =_ - _
P,Ueum =
0.2. . GOY!!1-!'tt 9{ sl ::
.4.i..~~....iil.l:.l ...
_NARRATtVE SUMMARY Dog 5097
{ NUMHEROF DAY3HOSPi'ALIZED
Page 6 _
is an intense congestion of the mucous
,.,-The mucous-membrane is intact. Th villi are prominent. In areas, there is
pffhe -cecum measures 5cm.
-ls intact.
avColon
I DATBOF DISCHARGE
The tissue1cuts with usual resistance. The mucous membrane
The mucous membrane of the ascending colon is intact and brown in appearance.
1'The mucous membrane of the transverse colon is intact and brown in appearance.
'The- mracous. membrane of the descending colon is intact and brown in appearance as is
T9he-.si&=idcolon.e j~he mucous membrane of;the rectum is.intact. The mucous
:--membrane of the anus is intact an&grey in appearance. " :
G_<i°ancreas -- _
..,...---- _---- :
the lobular architecture is maintained.
DIrM05E S ~'
~.
~. : ~:.._.. . ._ .~ . . ,,. , . .
T~,The,pancreas weighs 22.4gms. The tissue cuts with usual resistance and on section
- 1. Emboli in branches of the pulmonary artery of the left diaphragmatic
ci;apical lobes.
.fcs:'rF=
recent, left apical and left diaphragmatic.lobes.
3. Questionable thrombi in branches of the veins
-"k: "Pass3ve congestion of the lungs, advanced
5. Passive congestion of the viscera, moderate
7-2..-Pulmonarp infarct,
d

S
Steederd form 502
[ev. AoOua 1954
6ureauotThe Budg.r.
V.:.~:OVI!+':[vfifR 1471VU.0tci.1
. {)". .f"1: ; 4., ..r ,
Clreular A- 32CLINICAL RECORD (' NARRATIVE SUMMARY Dog 5097
DATE OF ADMiSS1ON'.
(Sign and dae at end ot narrative)
..
Sections Taken
Bottle A -two sections left apical lobe
Bottle B-two sections heft-cardiac lobe
Bottle C-two sections left diaphraLatic lobe
Bottle D-two sections right apical lobe
Bottle E-two sections right cardiac lobe
Bottle F-two sections right intermediate lobe
Bottle G-two sections right diaphragmatic lobe
I NVMBER OF DAYS IiO5P1TALIZED
I` Page 7
ILA1 & 1LA2 & LA6 & LAMLEFT APICAL LOBE
The capillaries of the interstitial tissue are moderately dilated and filled with
blood. In some areas within the subpleural zones the wa1Ls of the alveolar septa
are slightly thickened by an increase of connective tissue. The pulmonary
arterioles are of average thickness. The pulmonary arteries are of average thickness.
The bronchi are lined by columnar epithelial cells and show a very slight increase in
the number of basal cells. Lying in the lumens of some of the pulmonary arterioles
are thrombi compose&of red blood~cells chiefly, with occasional neutrophils
and mononuclear cells. Lying in the lumens of the alveoli are accumulations of
red blood cells, a few neutrophils and.mononuclear cells. In some alveoli there is
a prepondergnce of neutrophils. In thi alveolar spaces, particularly in Slide 1LA2,
are accumulations of neutrophils with occasional red blood ce1Ls and small amounts
of serum. In areas within the lung, particularly in Slide 1LA2, the alveoli contain
accumulations of serum, a few red blood cells and alveolar phagocytes. In Slide LA6
is a focus which is red granular in ap^earance and in this region are nuclear
fragments and the ghost forms of red blood cells. The alveolar septa are granular
in appearance and contain nuclear fragments. In the areas beyon&these the alveoli
contain serum, red blood cells and alveolar phagocyteso The overlying pleura is '
slightly thickened by an increase of_connective tissue. In Slide LA1~0 there is
a slight thickening of the walls of the alveolar septa and a rupture of the septa
beyond these to leave slightly enlarged air sacs.
(Use additional aheets of this form (Standard Form 502) if more apace is requirad)
SIGNATURE OF PkiYSICTAN
I DATE OF DISCNARGE
I DATE
I
ORGANIII.IITION
IDENTIFICATION NO.
~
PATIENT'S IDENTIFICATION (For typ.d or.utten,.erljFiea ~(irq;.lyaroe-leat, AraF
middle; /rad.; drte..Aoedit.L or rundi.aal:f.ta.GtY)
Dog 5097
NARRATIVE SUMMARY
O etanaaro Form 4502
~..~ ws-to-
~

.
The elastica van Gieson stain shows the elastic fibers intact at the pleuropulmonary
junction. ~The overlying pleura is slightly thickened by an increase of connective
tissue. The internal elastic lamina of the arteries is intact. The walls are of
ave"~age'thfckness:"'Fhe'elastic-°fram` aork' of the lung parenchyma is maintained.
Dog,5097
DATE OF ADMISSION ~ DA.TE OF D15CHARGE NUMHER.OF DAYS HOSPITALIZED
11 Page 8
(S; fci and datrat end of nasrat ic. {
ffARdartd Fpih 302
'
RiR. Al1§OR 1954
1a[tOC OI tha !<YdQd V.S..OORAaeCVi ta1RTCMC Op1Sa N'5-16-810u-1 60G-O.iO
QFtOtar A-32
CLINICAL RECORD ~ NARRATIVE SUMMARY
DIAGNOSES
1 ,. ~ .
1. ~-Pulmonary fibrosis and emphysema, slight
2. _Edema and congestion of the lungsl
i
3. '=:Pulmonary -emboli, recent `
4. .Infarct,-recent
i
arter-ioles.are,thrombi composed of-red bloo&cells predominately, a4ew neutrophils
and a.few mononuclear cells. The pulmonary arteries are of average thickness, In
Slidez =60 is .a.n alveaiar }f~illing process.. _.Here the alveoli contairi serum, 'red blood
cells, -neutrophils :and alveolar -phagocytes. '- The neutrophils 'predomiriate: -In focal
areajs within,the _lung the.alveoli contain accumulations of red'blood cells, some of
which have undergone neerosis. In_these areas the walls of the alveolar septa -
although intact qonta~n,nuClear fragLlents. In the regions beyond these the alveoli
contain serum, red blood cells and'alveolar phagocytes. The neutrophils predominate.
5. -:Acute bronchitis
6.. - Bronchopneumonia, xecent - -= .
7. Basal cell hyperplasia, slight to moderate
8. --Fibrous_thickening of.the, pleura, slight-
2LC1 & 2LC2 & LC1 & LC60 LEFT CARDIAC LOBE
1'he`capillaries of the-interstitiai..tiasue, are_moderatrely_dilated and filled'with
blood. Lying in the~lumens of some of thdi alveoli are accumulations of serum, red
blood cells and occasional alveolar phagocytes. The bronchi are-lined by tall
colunmar;..Aells ;and ,.show,.a, sli,ght;:izjcrease -iz:_the.. number of :basal cQ1Is. =--The
-gulmonary
arterioles are of average thickness. Lying-Yn the lumens of some of;the pulmonary ~
(Use additionaf sAeets of this form (Standard Form 107)' if rnora apaee is required, )
.
SIGNATURE aR PnfslclArr ;;
r 1DENTFFlCAT10N tJO. ORG VJIZA710K
PATIENT'S 1DENTtF'ICATIQN (Far t>p. doi xritte+~ entriae aive: Nem.-lsat, hrat, REGl5TER NO. __
middtr, (r.ds; d.tb: hospitvl or mediCaltacilJty) '
Dog 5097
i WARD NO.

Staaderi Ferm 302
Rar. Avyrop 1954
iweeP of The BedQet
0tt,ler A-32
V. :v ~ ,r~+, ..i tir.w ofnc. .13 ! (,, h1oSS-t wa Oy,
CLINICAL RECORD I NARRATIVE SUMMARY Dog 5097
DATE OF ADMISSION
I;NVM9ER OF DAYS HOSP{TALl2ED
I Page 9
DATE OFDIBCHARGE
(SiQn and date at end of narrat ve)
I
The lumens of the bronchi and bronchioles in these areas contain~accumulations of
neutrophils, desquamated epithelial cells and red bloo&cells. The walls of the
alveolar septa in the subpleural region are slightly thickened by an increase of
connective tissue. In the regions beyond these the alveolar septa are torn to
leave slightly enlarged air sacs. InXlide LC1 there is a slightly greater
thickening of the alveolar septa and so a tearing of a slightly greater degree
of the walls of the alveolar septa. The overlyingpleura is very slightly thickened
by an increase of connective tissue. ,
The elastica van Gieson stain shows the elastic fibers intact at the pleuropulmonary
junction. The overlying pleura is sli$11htly thicken-~d by an increase of connective
tissue. The internal elastic lamina of the arteries is intact. The walls are of
average thickness. The elastic framework of the lung parenchyma is intact.
DIAGNOSES
I. Pulmonary emboli, recent '
2. Infarcts, recent
3. Edema and congestion
4. Acute bronchitis
5. Bronchopneumonia, recent
6. Pulmonary fibrosis and emphysema, slio
7. Basal cell hyperplasia, slight
8. Fibrous thickening of the pleura, slight
3LD1 & 3LD2 & LD22 & LD28 & LD45 & LD275 & LD281 LEFT DIAPHRAG*ATIC LOBE
blood. Lying in some of the alveoli are accumulations of red bloo&cells, neutrophils
and alveolar phagocytes. Present in Slide 3LD1 are large red granular zones of
necrosis. Within this area the former structure of an alveolar filling process and
the underlying lung parenchyma is still discernible. Lying within the alveoli are red
The capillaries of the interstitial tissue are moderately dilated and filled with
(Use additional sheets of this form (Standard Form 502) if more spaco is required)
SIGNATURE-0F PHYSICTAN
I DATE
IDENTIFICATIONNO. I ORGANIZATION
PATIENT'S IDERTiFTCATtON (For typed or written entriealire; Name-last.Brat, I REGISTER NO. i WARD
NO.middle; /rade; date; hoapital or medicaf faciGty)
Dog 5097
t,ra;.w ,~a #e~ ~: ~.
NARRATIVE SUMMARY
atanaarn 1"orm so.
w_-l,r

N
--f,
t
3faeiaW rem 302
Rar. AaqoO 19SI
Mutrof t[t/ Rud9t
GiC01ar A-]2
`CLINICAL RECORD I
OATE OFADMISSION 1DATE OF OISCHARGE
vOT'~.t:y~~'a'IViGS145~,41f1'_. .4:L.V. vIC1L.. :. IC.'.,/li.
: NARRATIVE StJMMARY Dog 5097
NUMBER.OF pAYS HOSPlTALfZED
Page 10
- >~..>r - - ---- - - -
r': :(Sifn aad datr.at ettd oL natcarire ) ~
-,:blood cells and many nuclear fragr.Tents. The ghost forms of red blood.cells are
n~,.also discernible. These elements are also present within the lumens of some of the
w__bronehi.and bronchioles within this zone. Within this zone are branches of the pulmonary
cG&rtexiales';and arteries whose lumenscontain.accumulations o'f.red blood cells with a
..~ ._ --- ~'
few neutrophils and mononuclear cell . In the regions beyond these the alveoli
:contain accumulations of neutrophilst red blood cells and serum. The lumens of some
0_-of_.the bronchi in this region also contain accumulations of neutrophils with desquamated
z5:epithelial cells. A similar red'granular zone is`present in LD22, LD28, LD275 and LD281.
1.'£he-elastica van Gieson stain shows the elastic fibers intact within the lung
parenchyma. The elastic framework of the lung parenchyma is intact and also in the
,.areas__of_the infarct. The internal elastic lamina of the arteries is intact and the
walls are of average thickness. The elastic fibers are intact at the pleuropulmonary
_:,junction. The overlying pleura is slightly thickened by an increase of connective
tissue.
,ju_thickness:._The overlying pleura is 4ery slightly thickened by an increase of connective
z;.tissue.,;..In areas of intact lung par~nchyma the walls of the alveolar septa just
a--beneatl3 the pleura are slightly thickened by.an increase of connective tissue and in
the regions beyond these the alveolar septa are torn to leave slightly enlarged air
Disacs.
The bronchi are lined by columnar epithelial cells and show a slight increase in
>_the number of basal cells. The pulmonary arterioles and arteries are of average
DIAGNOSES
r
1. ETnboli, recent, branches of the pulmonary arterioles and arteries
C . r . ~-..__. -- ,_ ....
2. Znfarctsx recent
3. Acute bronchitis
C . 1 __ __ _ _
4. Bronchopneumonia, recent
_ -. ~ . .,.".._ ~
5. Edema and congestion
A ...~ t- ...._ .._.. ~. ~. _~. . . . ._ . ~~.- .-,- . .. '
Pulmonary fibrosis and emphysema, slight
,.
;°f'ibrous thickening of the pleura, &light
th°^ ...
(Use edditlonal shaets of this fosm (Standikrd Forirf 502) il more space ie .re-quired).
!~IW.f"3IGNATURE OF t1iYS[CtAN
+ DATE
aDENT1tr1G+TtON NO. k0lt6AN12ATiON
I
PATIENT'S TDENTIPICqTTOhf (For typ.d or writTSn.ntriea flrs: Nama-lest, firot, REGISTER ST;ER NO
_:aniddf.; erads; da.: hoapital or madiasl lec.lier)
°-;Dog 5097
r- WARD NO.
:..itURRATIYE SUMMARY
,~,= Ytaa4ara ~'orai sQ:
~ ~ iti,7-:5U_-TU'
