Lorillard
Narrative Summary Dog 6022
Fields
- Author
- Auerbach, O.
- Alias
- 01396831/01396832
- Site
- G65
- Master ID
- 01396810/6832
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- Type
- SCRT, SCIENTIFIC REPORT
- FORM, FORM
- Date Loaded
- 05 Jun 1998
- Request
- R1-004
- R1-041
- R1-046
- R1-047
- R1-053
- R1-068
- R1-132
- R1-041
- Document File
- 01396726/01396834/Enviro Control 80
- Area
- SPEARS/EVPOR
- Litigation
- Flag/Trial Exhibit 6988
- Stmn/Produced
- Txag/Trial Exhibit 6988
- Stmn/Produced
- UCSF Legacy ID
- esl88d00
Document Images
6.
Ui';1!CNL PECOZD !'
. lal.,I l i. ' t):.1 1 I1 r,,.~..
3. Pulmonary fibrosis and e,nuhy;e;na, slinNrt, illll lnh+. ,I `i;" .l,-fli
4. Acute bronchitis, all lobes of the lu!nq
5. Bronchopneumonia, recent, all lohes of the luriq
6. 3ronchopneumonia with abscess formation, right dia;)%irrramitic lo!b(r
i'. Basal cell hyperpliasia, sl'ight to moderat:e, all1 lo?)es of the liunq
8. Pulmonary edema, right apical and riignt cardiac lobes
9. Cranuloma, right cardiac lobe
1''0. Fibrous thickening, of the pleura, sliaint, bilateral
11. Squamous metaplasia of the trachea
12. Lymphoid, and reticulum celll hyperpla:sia of the tracheobronchial lymph nodes.
13. Coronary arteriolosclerosis, slight
14. Fatty infilltration of the myocardium
15. Passive congestilon of the liver, spl'een, pancreas and adrenals, slil~.y~~t
COMMENT
This is a dogifromithe PMO Study. The dog died duMing an emergency trearmer, in the
veterinary clinic. At the time of his death the dog ha6 smoked forll:3 days with a
total of 1140 ciioarettes smolced. The smoking began on /;pr; 1~', 1977. He smoked untiilr
October 18, 1977. The f i ndi ngs of thi s dog are those of a throm5us oF recerltori c i n
in the right auricular appendage. From here, showers of emboli were qiv'en o=t an!rl
landed i n branches -of the pullmonary arteries and arTeri ol es i n s i x of Llre severn
lo.bes. Following, thiis, pulmonary infarcts developed in six of the sev'e- ln!;~;. ".lo
- ~ ..
pulmonary infarcts were of recent origin an& in tne areas around zones of bronchopneumonia, a
frequent complication of pulmonary
infarcr.ii;~~. w:
interesting complication was the presence of a aul!.monar7y abscc;s in, ;ne r,~-jir,n the
infarct in the right d'iapfhragrnatic lobe. The changes in the trachpohrnnc,ii,~l' er)itiieliu*r,
were those of basalic~l 1 nypernlasia, more than one wmulu expect wi th a -ota l sojoki'nr-1Cl~r
oe,Rlws~C~nN i't)I: --. --.-- -:--- - -- -----
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Dog 5022

~ c.uneu.d forn+50'.
r . ~.k1V c1~tir d^.',~.
ccf:7~C~A--I
CLINICAL RECQRD
DA[L OF ADt1651VN
i DATfl 01 UI6CYiAItc,t'
N.at^n`,T1GC riV(','~..,iR ( 00C 602"1
PAGE 22
(S+Qn and'dsce ntrnJi nnrrwt ,r -
of 6 months as was present in this case. There was also evidence of early fibrosis
and emphysema in all lobes of the lunq. Granuloma, probably secondary to a worrn was
present in the right diaphragmatic lobe.
This is another dog in the PMO'series with thrombosis of the right auricular appendage
and~emboli to branches of the pulmonary arteries and arterioles tirilth resulting
infarction, secondary pneumonia and death.
gSUP. AlIEkDACH, M. Q.
Senior Medica7 1'nv9Stirle(1r
(Use nddifional shecls of this fonni !Sland.trrf Forrtt ii ra,nrr spnrn i. r~r; :i;. i`
SJGNATUNE OF PNYSICfAN DATE I0CNTItI'::\T:UrI'iU: C.Rf:ANIL..T1Of:
PATIENT'S IOENTIFICATION (Far typedon arrchnwntc a gnr-N..r»a- bt.r: fiY,t. firrl" , t'RP.O:, -- -
cnidd:e:Qrnde; dnte:hoeplteformrdre.+IYac :Itv
\VtRD.NO.
t{~~?1.ilYi SU4'YARY
.,:7t. :U.
