Tobacco Documents Online

0 'C.1NICit! RECOkC ..•- ~ I)1.1i Vf~ t.!I:•l.!Ir1,•:(yL rvh'2i'r.-" '!= S'JMrli.'',ryY Don ~ 5 3 M31 P(lnn' ?I (;SiQn:~nd'uato.~fcndnf t...,. 15. Browni pi qmentat.i on and fatty i nfi lltrati on of the trachonbronchiial l vmn'rj nodes. 16. Lymphoid reticulium cell hynernlasia of the tracheobronchial llvmnh nodes. 17. Coronary arteriolosclerosis, sliqht. 18. Fatty infiltration of the myocardlium. CO"''ENT TV i s a dog i n the Envi ro Control Seri es . The don had smoked i n th- "r-t() t;routi, (67 . Durind the period of 432 days of smokiinq, he had consumed 5,3LO cinrrrettes. Tho ,hanqes present iini thiis doq are those of thrornbi of recent ori n;i n wi ;-:hiin, the veiins of tPle extremi ti!es and' t~ioth~ auri cul ar apoendanes. As a resrul t' of the thrt)mhn' in Lrae right auricular appendaqe, emboli were showered i'nto al i lohes of tlie lunq. The embold were prel;o.nt in the pulmont3rv arteriolle; and pul!vlonarv arteries of all lobes of the lunn. This resulted in pulmnn,irv infarct-. nY recent origin in all seven lobes. Secondary to the pulmonary infarction, an acute bronchitis and a bronchopneumoniia of recent oriqin developed. In four of the seven lobes the areas of Dneumonia underwent liquefactiion and iibscess formation. As far as the cirect chanqes secondary to cigarette smoking, they were of sliahtt to moderate degree. These were present in the form of a oulmonary fiibrosiis and, emphysema of a slight to moderate degree and'1 also a basal cell hyoerolasia of a sl i Qht to mod'erate degree with slli'qht to moderate atypi sm. When the changes i'inithese doqs are compared wiith those of the fi r;t study that werr• ki l l ed between. 421 and 423 days of smoki nq,, the riind'.i nns i n thi s doo art, far less than ±'',ose whiich we observed! in our first swoi..inq stu'liv.. , OS(,~~RJ Ai'i1l'Z1,ri('.?~;" t~. D. Di'sti n(1,ui shr(ll PhySi ci an ! o1,rroary 9, 1')71) OA:Ih (U§e uddit:r.nnl shctets of this form (SfAnd.lyd Forrn 501) if rnorn 3pNr n i'o r..qulrnrf)! SlGtl;.".fURE OF PI1t'S.IC12.t1 ---~ ' D•1TC _--/ IU~IFICaiT.IOM NU:.I ORGANILA7i6UN' t1 (l PATn. rIT•5~ IUUNTiiF1CATIUN (For~ typo:d~or n-nitt.>n e.ntrir.e Nnme-l.ie(. firat, midJPn; s+rede;,dstr: ~hoapitnl or~trtrdicnl f'uutitp)~ RF.GI6~TER~ NL)i. I Y.' A R,7 .`.0. 1 NAFRAT!lYE SUMMAh1, Ht.utdnnl t'orrn ';.,_ f:c:nrrali $etsmrs tA-mt:*a•'cn, on! '.. .rrn¢v'Camm.ttee on ht~dr:ll et3-tb-•n•r'-_ ar o