Lorillard
Methods for Environmental Tobacco Smoke Measurement
Fields
- Alias
- 01335452/01335453
- Area
- SPEARS/OFFICE
- Type
- SREP, SCIENTIFIC RESEARCH PROPOSAL
- Date Loaded
- 05 Jun 1998
- Document File
- 01335447/01335469/Missing. Dr Melvin First Harvard
- Request
- R1-004
- R1-034
- R1-132
- Named Person
- Grubner, O.
- Hinds, W.
- Site
- G65
- Litigation
- Stmn/Produced
- Master ID
- 01335452/5459
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Methods for
Environmental Tobacco Smoke Measurement
The use of carbon monoxide (CO) and total particulate matter as
markers for estimating levels of tobacco smoke in public places has received
much attention in the current literature on environmental tobacco smoke.
Although measurements of CO and particulate matter provide useful information
for assessing indoor air quality, they are ill-defined surrogates for tobacco
smoke. Measurements using CO or total particulate matter are likely to
overestimate contributions of tobacco smoke to indoor environments, because
neither is specific to tobacco smoke. Nicotine, on the other hand, is specific
to tobacco smoke and, as my colleague William Hinds and I showed in 1975
(attached), can be measured in public places and used as a marker for tobacco
smoke.
In order to critically assess studies which have used surrogate
indices for measuring environmental tobacco smoke, I propose a pilot project
designed to define the relationship among the several methods that have been
used to measure tobacco smoke in indoor environments. Of particular interest
-will be the methods which have employed carbon monoxide, total suspended
particulate matter, and nicotine for measurement standards.
Specifically, the proposal consists of two parts:
A. Baseline comparative data for carbon monoxide, total particulate matter,
and nicotine will be determined initially in controlled room studies. A

direct reading, oscillating crystal instrument will be used to monitor total
suspended particulate (TSP); a direct reading Ecolyzer (with and without an
activated charcoal trap to remove organic vapors) will be used to measure
carbon monoxide; and a filter sample (with appropriate treatment) will be
employed for nicotine collection. Nicotine samples will be analyzed by gas
chromatography using a method described by Dr. Otto Grubner and myself in an
1980 publication (attached). -
B. The most important part of this pilot study will involve simultaneous
measurements of CO, nicotine, and TSP's in various public places, e.g., offices,
restaurants, recreational and travel locations. Using nicotine measurements
as principal standards, data on the relative amounts of airborne tobacco smoke
indicated by each sampler (for CO and TSPs) will be obtained. Parameters such
as room volumes, the number of persons present, the number of active smokers
and cigarettes smoked, background levels of C0, nicotine, and TSP's, sampling
times, and locations of samplers will be noted. It is expected that the
results of these experiments will permit an evaluation of the actual level of
tobacco smoke reported in studies which were conducted using CO or total
suspended particulate matter as markers for environmental tobacco smoke.
~;~.
