Tobacco Documents Online

33 ~ i Vari ous Regi ons of: th&V Jolrld ny of these sembled here and vAll be aee- hot conittmpt{op Tut tpowa, 1S43. With lyzed to aea it any form ot an- Dr- Jmaen aai, that heavy, lish Govern- eer was unusually rnmmon. ~• drinliars (withmt epeclfying :ates for sn A mpt Norweghn a uvey the baveseg¢) tmd mors 9ftm -a_.5UU who`ia which ik,090 men were to de~etop uncer ot ths colon ze being as-lasked to state their daily alco-;or teeWm-

- •, tal TlL... r.d n~"ks been ady because public 4 , tics, inc;uding cancer d.ions, are complete an ilogical information on the .re population iilaLle: ~ i project is be7 tly f-d mced by the na~ :ar.cer~ Institute in the [ Sl tates,l as are several oO ~ 1s of the center-here. The_ center-id-.a W with - the World Health O s_ tion. but, In cuntras@ to ~1 road .- member ship of iIM -_ Ita members are limited - d in- dustrialized natiors._The Sovlet Union is the only,Communist bloc participant .. . - Esophagus Problep . Perhaps the most stubborn puzzle is the extensive occur- rence of cancer of the esopha- i s In certain. regions. Among em are Brittany and Normany in France where apple brandy (calvados) is a favorke drink among men. Soviet researchers and others here proposed severl al years ago that contaminants,l known as nittosamines, migbt' be to blame, particularly in home-made versions of the drink. ' In a snrvey of one county in sritanny, such substances were detected in small quanti- ties, whereas they were not found in American brands of apple brandy. But it was also found from case histories that the strongest predispositfon to cancer of the esophagus lay with those who both drank and smokedheavily, whatever the nature of the beverage. A similar study is now under way in Normandy. The most dramatic local oc-

---