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Lorillard

Date: 1972 (est.)
Length: 4 pages
00037862-00037865
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Alias
00037862/00037865
Area
MINNEMEYER/OFFICE
Type
LIST, LIST
Master ID
00037860/7865
Related Documents:
Date Loaded
27 Feb 1998
Document File
00037700/00037868/Res Proposals
Request
R1-039
R1-045
R1-046
R1-004
Litigation
Flag/Trial Exhibit 2388
Morm/Trial Exhibit 1502
Stmn/Produced
Stmn/Selected
Txag/Trial Exhibit 2388
Site
G46
UCSF Legacy ID
sun99d00

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Health - Present data indicates need to measure non-volatile ~ and/or high mol. wt. components ( liped content) of both, leaf and smoke. Liquidichromatography may be best available approach. These may apply to both Health & Flavor a'reas. Health - Continue studies aimed'at correlating smoke composition with observed biological effects. Health - Develop short term bioassay for smoke & smoke fractions. Health - Removal of Isoprene precursors from tobacco (via solventt extraction) and evaluation of resulting product inichemical and bioassay tests. Flavor - Continue investigation of smoke components associated with sensory strength characteristics. This most likely involves nitrogen containing compounds and will involve a, study of amino acid content of leaf. Flavor - Continue and expand study of'turkish characteris!tics related to formic acid fraction. Identify specific compounds. and investigate possibility of'synthe izing appropriate additives. Flavor - Reconstituted tobacco extension and modification with inorganic or organic additives.. This may include volume and/or flavor enhancement. Flavor - Developlanalytical capability of measuring extent of desirable Browning Reactions during processing and smoking. This will allow enhancement of desirable reactions and/or supression of others.. Flavor - Investigate correlation of leaf composition with flavor characteristics. QC-Mfg. Support - Investigate relationship between leaf physical properties ('processability), chemical properties (leaf grades), and trace metal contents with a view toward modiifying our present leaf'analysis measurements. QC'-Mfg. Support - Analysis of expanded tobacco for FC-11 residues and analysis of incoming F'C-11 for impurities. QC-Mfg. Support - Development of particle size test method for production quality control use. QC-Mfg,. Support - Monitor environmental conditions in and around processing,facilities. . OQC-Mfg. Support - Investigate and/or develop methods for auto- O mated moisture control in plant processes. C~ 4.1 QC-Mfg. Support - Monitor tobacco filling values and develop 00 methods for control and optimization. ~, QC-Mfg;. Support - Investigate methods of controlling the rate of cigarette burn to allow the use of minimum cigarette weight.
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QC-Mfg. Support - Review incoming material and product specifications and testing methods to insure that the specifications meaningfully reflect our minimum requirements and that the measurements used are reliable. . QC'-Mfg. Support - Continue development of an efficient and' effective insect control program for storage and processing areas. QC-Mfg. Support - Improve methods and techniques for the analysis of tar and nicotine yield to minimize the manpower and cost required. W
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QC-Mfg. Support - Continue development of C C-Mass Spec capability for use as a general analytical tool QC-Mfg. Support - Improve blend component tracer techniques to be used in periodic checks of manufacturing,processes. Health - Inhalation experiments to determine the fate of indiividual chemical smoke costituents and their rate of'clearence from animal lungs. Health - Investigate physiological effects of physiologically active ..components of added flavoring,materials withia view toward enhancing these effects if desirable. QC-Mfg. Support - Investigate automated! cigarette inspection system (loose-ends, pressure drop, circumference) QC-Mfg. Support - Analysis of'composite grade samples (volume, smoking, Leaf Anallysis,, moisture hysteresis, etc.) to give average characteristic for each crop year. Flavor - Investigate composition of natural flavoring materials to determine possibility using synthetics. -•Vew Product --Develope both high tar and low tar products to hold in reserve for future introduction quickly if market conditions warrant. New Product - Investigate physical filter configurations to alter tar nicotine rati'o. New Product - Develop filter to be compatable with a PMO'product.. New Product - Continue development of PMO as tobacco aaditive. Health - Develope animal test system to screen effects on respiratory system, QC-Mfg. Support - S'EED'-LEAF TOBACCO FERMENTATION. Learn basic information regarding the fermentation processes useful to Lorillard to remain competitive and improve quality. An objective is to automate and accelerate the process, obtain a more uniform product, shorten storage times. Investigate possibility of innoculations with a specific organism to obtain specific result.
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COMPUTER ASSISTED TOBACCO FLAVOR PROFILE' Gas chromatographic breakdown of flavor or compositional constituents assisted by completely automated integration and computer analysis. TOXICOLOGY OF TOBACCO ADDITIVES' Investiigate tof.icology of tobacco or flavor additives used by Lorillard,,or unique to Lorillard, with view to finding anything unfavorable before someone else does, or demonstrating absence of any harmful effects. MARIJUANA Obtain background information in this area by.surveying and monitoring,the literature. Investigate possibility of making, Marijuana cigarettes on government contract for investigative purposes, and contract for investigating same. Project objective would be to be in advantageous position in the event Marijuana were leagallized and Lorillard wished entry into the f ield .

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