Lorillard
Fields
- Alias
- 00037862/00037865
- Area
- MINNEMEYER/OFFICE
- Type
- LIST, LIST
- Master ID
- 00037860/7865
Related Documents: - Date Loaded
- 27 Feb 1998
- Document File
- 00037700/00037868/Res Proposals
- Request
- R1-039
- R1-045
- R1-046
- R1-004
- R1-045
- Litigation
- Flag/Trial Exhibit 2388
- Morm/Trial Exhibit 1502
- Stmn/Produced
- Stmn/Selected
- Txag/Trial Exhibit 2388
- Morm/Trial Exhibit 1502
- Site
- G46
- UCSF Legacy ID
- sun99d00
Document Images
Health - Present data indicates need to measure non-volatile
~ and/or high mol. wt. components ( liped content) of both, leaf
and smoke. Liquidichromatography may be best available
approach. These may apply to both Health & Flavor a'reas.
Health - Continue studies aimed'at correlating smoke composition
with observed biological effects.
Health - Develop short term bioassay for smoke & smoke fractions.
Health - Removal of Isoprene precursors from tobacco (via solventt
extraction) and evaluation of resulting product inichemical and
bioassay tests.
Flavor - Continue investigation of smoke components associated
with sensory strength characteristics. This most likely
involves nitrogen containing compounds and will involve a,
study of amino acid content of leaf.
Flavor - Continue and expand study of'turkish characteris!tics
related to formic acid fraction. Identify specific compounds.
and investigate possibility of'synthe izing appropriate additives.
Flavor - Reconstituted tobacco extension and modification with
inorganic or organic additives.. This may include volume and/or
flavor enhancement.
Flavor - Developlanalytical capability of measuring extent of
desirable Browning Reactions during processing and smoking.
This will allow enhancement of desirable reactions and/or
supression of others..
Flavor - Investigate correlation of leaf composition with flavor
characteristics.
QC-Mfg. Support - Investigate relationship between leaf physical
properties ('processability), chemical properties (leaf grades),
and trace metal contents with a view toward modiifying our
present leaf'analysis measurements.
QC'-Mfg. Support - Analysis of expanded tobacco for FC-11 residues
and analysis of incoming F'C-11 for impurities.
QC-Mfg. Support - Development of particle size test method for
production quality control use.
QC-Mfg,. Support - Monitor environmental conditions in and around
processing,facilities.
. OQC-Mfg. Support - Investigate and/or develop methods for auto- O
mated moisture control in plant processes. C~
4.1
QC-Mfg. Support - Monitor tobacco filling values and develop 00
methods for control and optimization. ~,
QC-Mfg;. Support - Investigate methods of controlling the rate
of cigarette burn to allow the use of minimum cigarette weight.

QC-Mfg. Support - Review incoming material and product
specifications and testing methods to insure that the
specifications meaningfully reflect our minimum requirements
and that the measurements used are reliable. .
QC'-Mfg. Support - Continue development of an efficient and'
effective insect control program for storage and processing
areas.
QC-Mfg. Support - Improve methods and techniques for the
analysis of tar and nicotine yield to minimize the manpower
and cost required.
W

QC-Mfg. Support - Continue development of C C-Mass Spec capability for
use as a general analytical tool
QC-Mfg. Support - Improve blend component tracer techniques to be used
in periodic checks of manufacturing,processes.
Health - Inhalation experiments to determine the fate of indiividual
chemical smoke costituents and their rate of'clearence from animal
lungs.
Health - Investigate physiological effects of physiologically active
..components of added flavoring,materials withia view toward enhancing
these effects if desirable.
QC-Mfg. Support - Investigate automated! cigarette inspection system
(loose-ends, pressure drop, circumference)
QC-Mfg. Support - Analysis of'composite grade samples (volume, smoking,
Leaf Anallysis,, moisture hysteresis, etc.) to give average characteristic
for each crop year.
Flavor - Investigate composition of natural flavoring materials to
determine possibility using synthetics.
-Vew Product --Develope both high tar and low tar products to hold
in reserve for future introduction quickly if market conditions warrant.
New Product - Investigate physical filter configurations to alter tar
nicotine rati'o.
New Product - Develop filter to be compatable with a PMO'product..
New Product - Continue development of PMO as tobacco aaditive.
Health - Develope animal test system to screen effects on respiratory
system,
QC-Mfg. Support -
S'EED'-LEAF TOBACCO FERMENTATION.
Learn basic information regarding the fermentation processes
useful to Lorillard to remain competitive and improve quality.
An objective is to automate and accelerate the process, obtain
a more uniform product, shorten storage times. Investigate
possibility of innoculations with a specific organism to obtain
specific result.

COMPUTER ASSISTED TOBACCO FLAVOR PROFILE'
Gas chromatographic breakdown of flavor or compositional constituents
assisted by completely automated integration and computer analysis.
TOXICOLOGY OF TOBACCO ADDITIVES'
Investiigate tof.icology of tobacco or flavor additives used by
Lorillard,,or unique to Lorillard, with view to finding anything
unfavorable before someone else does, or demonstrating absence of
any harmful effects.
MARIJUANA
Obtain background information in this area by.surveying and
monitoring,the literature. Investigate possibility of making,
Marijuana cigarettes on government contract for investigative
purposes, and contract for investigating same. Project
objective would be to be in advantageous position in the event
Marijuana were leagallized and Lorillard wished entry into the
f ield .
